Construct: sgRNA BRDN0001145436
Construct Description:
- Construct Type:
- sgRNA
- Other Identifiers:
- n/a
- DNA Barcode:
- ACTTGTGGCCAATATGCTGT
Original Target:
- Taxon:
-
Homo sapiens (human)
- Gene:
- PRPS2 (5634)
- Gene Description:
- n/a
- CRISPR Mechanism
- CRISPRko
Vector Information:
- Vector Backbone:
- pXPR_003
- Pol II Cassette 1:
- EF1A-PuroR
- Pol II Cassette 2:
- n/a
- Selection Marker:
- PuroR
- Visible Reporter:
- n/a
- Epitope Tag:
- n/a
Additional Information:
- Addgene ID:
- 78008
Gene matches for this target sequence (CRISPRko, PAM=NGG, human):
Gene matches for this target sequence (CRISPRko, PAM=NGG, mouse):
| Reference Sequence |
Chromosome |
Cut Position |
Match Strand |
Match Gene |
Match Sequence |
PAM Seq. |
Mismatches[?]Genomic matches are found by querying with a reduced sequence corresponding to the final 17mer of the 20mer guide target sequence, combined with the `GG` of the PAM sequence. Mismatches are assessed within this set of bases only, for a total of 19 possible matching bases. |
CFD Score[?]Off target matches are assesed via a Cutting Frequency Determination, or CFD score. This value provides an estimate of how specific mismatches affect the likelihood that an sgRNA will cut a given target sequence. For more information, see Doench, Fusi et al., Nature Biotechnology 2016. |
Match Tier[?]For a description of CRISPR match tiers, see How the sgRNA Designer Works. |
1 |
NC_000083.6 |
17 |
22146483 |
+ |
Zfp947 |
NNNTGTGGATAATATGCTGT |
NGG |
2 |
0.8067 |
Tier I |
2 |
NC_000083.6 |
17 |
21881043 |
+ |
Zfp995 |
NNNCGTGGACAATATGCTGT |
NGG |
2 |
0.5546 |
Tier I |
3 |
NC_000086.7 |
X |
167365178 |
- |
Prps2 |
NNNTGTGGCCAATATGCTGT |
NAG |
1 |
0.2593 |
Tier I |
4 |
NC_000080.6 |
14 |
103154900 |
- |
Mycbp2 |
NNNTGTGGCCGATATGCTGG |
NGG |
2 |
0.1147 |
Tier I |
5 |
NC_000069.6 |
3 |
15514536 |
- |
Sirpb1b |
NNNTGTGGACAATATGCTGT |
NGG |
1 |
0.8571 |
Tier II |
6 |
NC_000071.6 |
5 |
9462741 |
+ |
Elapor2 |
NNNTGAGGCAAATATGCTGT |
NGG |
2 |
0.7511 |
Tier II |
7 |
NC_000079.6 |
13 |
20422361 |
+ |
Elmo1 |
NNNTGTGGAAAATATGCTGT |
NGG |
2 |
0.7429 |
Tier II |
8 |
NC_000072.6 |
6 |
5131129 |
+ |
Ppp1r9a |
NNNTGTGGGCAATGTGCTGT |
NGG |
2 |
0.2889 |
Tier II |
9 |
NC_000075.6 |
9 |
80110162 |
- |
Senp6 |
NNNTGTTGCCAATATGCTGT |
NAG |
2 |
0.1481 |
Tier II |
10 |
NC_000076.6 |
10 |
64793478 |
- |
Ctnna3 |
NNNTTTGGCCAATGTGCTGT |
NGG |
2 |
0.14 |
Tier II |
11 |
NC_000077.6 |
11 |
107625249 |
- |
Helz |
NNNTGTGGCCAATCTGATGT |
NGG |
2 |
0.1 |
Tier II |
12 |
NC_000076.6 |
10 |
82680332 |
+ |
Glt8d2 |
NNNTGTGGCCAATATGATGT |
NTG |
2 |
0.0182 |
Tier II |
13 |
NC_000067.6 |
1 |
84523829 |
- |
Dner |
NNNTGTGGCCAACATGCTGT |
NGT |
2 |
0.0127 |
Tier II |
14 |
NC_000069.6 |
3 |
15514536 |
- |
Gm21014 |
NNNTGTGGACAATATGCTGT |
NGG |
1 |
0.8571 |
Tier III |
15 |
NC_000083.6 |
17 |
22068850 |
+ |
Gm7818 |
NNNTGTGGACAATATGTTGT |
NGG |
2 |
0.4 |
Tier III |
16 |
NC_000072.6 |
6 |
116798729 |
- |
Gm36873 |
NNNTATGGCCAAGATGCTGT |
NGG |
2 |
0.2261 |
Tier III |
17 |
NC_000077.6 |
11 |
51200166 |
- |
Platr20 |
NNNTGTGGCCAATAGGCTGA |
NGG |
2 |
0.0281 |
Tier III |
18 |
NC_000069.6 |
3 |
87966762 |
+ |
Gm3745 |
NNNTGTGGCCCATATGCTGT |
NTG |
2 |
0.0156 |
Tier III |
19 |
NC_000068.7 |
2 |
48433591 |
+ |
Gm13481 |
NNNTGTTGCCAATATGCTGT |
NGC |
2 |
0.0127 |
Tier III |
Other clones with same target sequence:
(none)