Construct: sgRNA BRDN0001145652
Construct Description:
- Construct Type:
- sgRNA
- Other Identifiers:
- n/a
- DNA Barcode:
- ATATGACACTGCAATTTGGG
Original Target:
- Taxon:
-
Homo sapiens (human)
- Gene:
- NMRK1 (54981)
- Gene Description:
- n/a
- CRISPR Mechanism
- CRISPRko
Vector Information:
- Vector Backbone:
- pXPR_003
- Pol II Cassette 1:
- EF1A-PuroR
- Pol II Cassette 2:
- n/a
- Selection Marker:
- PuroR
- Visible Reporter:
- n/a
- Epitope Tag:
- n/a
Additional Information:
- Addgene ID:
- 75830
Gene matches for this target sequence (CRISPRko, PAM=NGG, human):
| Reference Sequence |
Chromosome |
Cut Position |
Match Strand |
Match Gene |
Match Sequence |
PAM Seq. |
Mismatches[?]Genomic matches are found by querying with a reduced sequence corresponding to the final 17mer of the 20mer guide target sequence, combined with the `GG` of the PAM sequence. Mismatches are assessed within this set of bases only, for a total of 19 possible matching bases. |
CFD Score[?]Off target matches are assesed via a Cutting Frequency Determination, or CFD score. This value provides an estimate of how specific mismatches affect the likelihood that an sgRNA will cut a given target sequence. For more information, see Doench, Fusi et al., Nature Biotechnology 2016. |
Match Tier[?]For a description of CRISPR match tiers, see How the sgRNA Designer Works. |
1 |
NC_000009.12 |
9 |
75077527 |
+ |
NMRK1 |
NNNTGACACTGCAATTTGGG |
NGG |
0 |
1.0 |
Tier I |
2 |
NC_000012.12 |
12 |
56120832 |
- |
ZC3H10 |
NNNTGAAACGGCAATTTGGG |
NGG |
2 |
0.375 |
Tier I |
3 |
NC_000010.11 |
10 |
48777643 |
+ |
WDFY4 |
NNNTAATACTGCAATTTGGG |
NGG |
2 |
0.7042 |
Tier II |
4 |
NC_000013.11 |
13 |
45712092 |
+ |
CBY2 |
NNNGGACACAGCAATTTGGG |
NGG |
2 |
0.5357 |
Tier II |
5 |
NC_000004.12 |
4 |
87217749 |
- |
KLHL8 |
NNNTGTAACTGCAATTTGGG |
NGG |
2 |
0.5357 |
Tier II |
6 |
NC_000021.9 |
21 |
44682763 |
- |
TSPEAR |
NNNTGACACTGCATTTTGGA |
NGG |
2 |
0.5 |
Tier II |
7 |
NC_000020.11 |
20 |
16363840 |
+ |
KIF16B |
NNNTGCCACTGAAATTTGGG |
NGG |
2 |
0.3247 |
Tier II |
8 |
NC_000014.9 |
14 |
99545315 |
+ |
CCDC85C |
NNNTGACACTGCAATGTGGA |
NGG |
2 |
0.3245 |
Tier II |
9 |
NC_000001.11 |
1 |
11204166 |
- |
MTOR |
NNNTGAATCTGCAATTTGGG |
NGG |
2 |
0.3214 |
Tier II |
10 |
NC_000020.11 |
20 |
51800408 |
- |
SALL4 |
NNNTGCCACTGCGATTTGGG |
NGG |
2 |
0.2964 |
Tier II |
11 |
NC_000014.9 |
14 |
103050810 |
+ |
CDC42BPB |
NNNTGACTCTGCAATTTTGG |
NGG |
2 |
0.2857 |
Tier II |
12 |
NC_000003.12 |
3 |
56430546 |
+ |
ERC2 |
NNNTAACACTGCACTTTGGG |
NGG |
2 |
0.1857 |
Tier II |
13 |
NC_000002.12 |
2 |
158342290 |
- |
CCDC148 |
NNNTGACACAGCACTTTGGG |
NGG |
2 |
0.1837 |
Tier II |
14 |
NC_000003.12 |
3 |
33545668 |
+ |
CLASP2 |
NNNTCACACTGCACTTTGGG |
NGG |
2 |
0.1684 |
Tier II |
15 |
NC_000004.12 |
4 |
41161786 |
- |
APBB2 |
NNNTTACACTGGAATTTGGG |
NGG |
2 |
0.1333 |
Tier II |
16 |
NC_000004.12 |
4 |
182125900 |
+ |
TENM3 |
NNNTGACAATGCAATTTGGG |
NGA |
2 |
0.0595 |
Tier II |
17 |
NC_000012.12 |
12 |
5493684 |
+ |
NTF3 |
NNNTGACACTGCAATATGGG |
NGC |
2 |
0.0202 |
Tier II |
18 |
NC_000007.14 |
7 |
114570465 |
- |
FOXP2 |
NNNTGACACTGCAATTTTGG |
NGT |
2 |
0.0108 |
Tier II |
19 |
NC_000018.10 |
18 |
39897105 |
+ |
LINC01901 |
NNNTCACACTGCAATTTGGG |
NGG |
1 |
0.7857 |
Tier III |
20 |
NC_000021.9 |
21 |
24944585 |
- |
LINC01692 |
NNNTAATACTGCAATTTGGG |
NGG |
2 |
0.7042 |
Tier III |
21 |
NC_000020.11 |
20 |
45431658 |
- |
LOC105372631 |
NNNTCAGACTGCAATTTGGG |
NGG |
2 |
0.3697 |
Tier III |
22 |
NC_000021.9 |
21 |
16180087 |
+ |
MIR99AHG |
NNNTGACACAGCAATTTGGG |
NAG |
2 |
0.2222 |
Tier III |
23 |
NC_000017.11 |
17 |
14844794 |
+ |
LINC02096 |
NNNCGACACTGCAATTTGGG |
NAG |
2 |
0.1678 |
Tier III |
24 |
NC_000005.10 |
5 |
160469436 |
- |
MIR3142HG |
NNNGGACACTGCACTTTGGG |
NGG |
2 |
0.1339 |
Tier III |
Gene matches for this target sequence (CRISPRko, PAM=NGG, mouse):
| Reference Sequence |
Chromosome |
Cut Position |
Match Strand |
Match Gene |
Match Sequence |
PAM Seq. |
Mismatches[?]Genomic matches are found by querying with a reduced sequence corresponding to the final 17mer of the 20mer guide target sequence, combined with the `GG` of the PAM sequence. Mismatches are assessed within this set of bases only, for a total of 19 possible matching bases. |
CFD Score[?]Off target matches are assesed via a Cutting Frequency Determination, or CFD score. This value provides an estimate of how specific mismatches affect the likelihood that an sgRNA will cut a given target sequence. For more information, see Doench, Fusi et al., Nature Biotechnology 2016. |
Match Tier[?]For a description of CRISPR match tiers, see How the sgRNA Designer Works. |
1 |
NC_000086.7 |
X |
160454131 |
+ |
Adgrg2 |
NNNTGACACTAGAATTTGGG |
NGG |
2 |
0.4444 |
Tier II |
2 |
NC_000070.6 |
4 |
145433227 |
+ |
Gm42346 |
NNNTGTCACTGTAATTTGGG |
NGG |
2 |
0.3846 |
Tier II |
3 |
NC_000070.6 |
4 |
145588447 |
+ |
Gm13212 |
NNNTGTCACTGTAATTTGGG |
NGG |
2 |
0.3846 |
Tier II |
4 |
NC_000070.6 |
4 |
145673737 |
+ |
Zfp980 |
NNNTGTCACTGTAATTTGGG |
NGG |
2 |
0.3846 |
Tier II |
5 |
NC_000070.6 |
4 |
146513793 |
+ |
Zfp981 |
NNNTGTCACTGTAATTTGGG |
NGG |
2 |
0.3846 |
Tier II |
6 |
NC_000070.6 |
4 |
146513793 |
+ |
Zfp993 |
NNNTGTCACTGTAATTTGGG |
NGG |
2 |
0.3846 |
Tier II |
7 |
NC_000070.6 |
4 |
146614689 |
+ |
Zfp993 |
NNNTGTCACTGTAATTTGGG |
NGG |
2 |
0.3846 |
Tier II |
8 |
NC_000070.6 |
4 |
146974953 |
+ |
Rex2 |
NNNTGTCACTGTAATTTGGG |
NGG |
2 |
0.3846 |
Tier II |
9 |
NC_000070.6 |
4 |
146974953 |
+ |
Zfp993 |
NNNTGTCACTGTAATTTGGG |
NGG |
2 |
0.3846 |
Tier II |
10 |
NC_000070.6 |
4 |
147135751 |
+ |
Zfp991 |
NNNTGTCACTGTAATTTGGG |
NGG |
2 |
0.3846 |
Tier II |
11 |
NC_000070.6 |
4 |
147135751 |
+ |
Zfp978 |
NNNTGTCACTGTAATTTGGG |
NGG |
2 |
0.3846 |
Tier II |
12 |
NC_000070.6 |
4 |
147233360 |
+ |
Zfp978 |
NNNTGTCACTGTAATTTGGG |
NGG |
2 |
0.3846 |
Tier II |
13 |
NC_000070.6 |
4 |
147363817 |
+ |
Zfp978 |
NNNTGTCACTGTAATTTGGG |
NGG |
2 |
0.3846 |
Tier II |
14 |
NC_000070.6 |
4 |
147452723 |
+ |
Zfp982 |
NNNTGTCACTGTAATTTGGG |
NGG |
2 |
0.3846 |
Tier II |
15 |
NC_000070.6 |
4 |
147495389 |
+ |
Zfp982 |
NNNTGTCACTGTAATTTGGG |
NGG |
2 |
0.3846 |
Tier II |
16 |
NC_000070.6 |
4 |
147640000 |
- |
Zfp979 |
NNNTGTCACTGTAATTTGGG |
NGG |
2 |
0.3846 |
Tier II |
17 |
NC_000070.6 |
4 |
147806172 |
- |
Zfp984 |
NNNTGTCACTGTAATTTGGG |
NGG |
2 |
0.3846 |
Tier II |
18 |
NC_000084.6 |
18 |
36048398 |
+ |
Nrg2 |
NNNTGACACTGCAATTTGAC |
NGG |
2 |
0.3061 |
Tier II |
19 |
NC_000069.6 |
3 |
95117272 |
- |
Vps72 |
NNNTGGCACTGCAATTTGGG |
NAG |
2 |
0.1852 |
Tier II |
20 |
NC_000078.6 |
12 |
71169346 |
+ |
2700049A03Rik |
NNNTGACACTGGAATTTGGG |
NAG |
2 |
0.1152 |
Tier II |
21 |
NC_000082.6 |
16 |
41755203 |
- |
Lsamp |
NNNTGACACTGCTATTTGGG |
NAG |
2 |
0.0778 |
Tier II |
22 |
NC_000072.6 |
6 |
92841313 |
- |
Adamts9 |
NNNTGACACTGGAAGTTGGG |
NGG |
2 |
0.0222 |
Tier II |
23 |
NC_000081.6 |
15 |
41503534 |
+ |
Oxr1 |
NNNTGAGACTGCAATTTGGG |
NTG |
2 |
0.0183 |
Tier II |
24 |
NC_000081.6 |
15 |
83865891 |
- |
Gm41372 |
NNNTGACGCTGCATTTTGGG |
NGG |
2 |
0.3911 |
Tier III |
25 |
NC_000070.6 |
4 |
146513793 |
+ |
Vmn2r-ps16 |
NNNTGTCACTGTAATTTGGG |
NGG |
2 |
0.3846 |
Tier III |
26 |
NC_000070.6 |
4 |
146614689 |
+ |
LOC115486238 |
NNNTGTCACTGTAATTTGGG |
NGG |
2 |
0.3846 |
Tier III |
27 |
NC_000071.6 |
5 |
146589275 |
- |
Gm34333 |
NNNTGACACAGGAATTTGGG |
NGG |
2 |
0.381 |
Tier III |
28 |
NC_000067.6 |
1 |
119314807 |
+ |
Gm33388 |
NNNTGACACTGCAATTTGAG |
NGA |
2 |
0.0496 |
Tier III |
29 |
NC_000072.6 |
6 |
92841313 |
- |
A730049H05Rik |
NNNTGACACTGGAAGTTGGG |
NGG |
2 |
0.0222 |
Tier III |
Other clones with same target sequence:
(none)