Construct: sgRNA BRDN0001145935
Construct Description:
- Construct Type:
- sgRNA
- Other Identifiers:
- n/a
- DNA Barcode:
- TCAGGCCCATATGAACAGAG
Original Target:
- Taxon:
-
Homo sapiens (human)
- Gene:
- ATP23 (91419)
- Gene Description:
- n/a
- CRISPR Mechanism
- CRISPRko
Vector Information:
- Vector Backbone:
- pXPR_003
- Pol II Cassette 1:
- EF1A-PuroR
- Pol II Cassette 2:
- n/a
- Selection Marker:
- PuroR
- Visible Reporter:
- n/a
- Epitope Tag:
- n/a
Additional Information:
- Addgene ID:
- 77435
Gene matches for this target sequence (CRISPRko, PAM=NGG, human):
| Reference Sequence |
Chromosome |
Cut Position |
Match Strand |
Match Gene |
Match Sequence |
PAM Seq. |
Mismatches[?]Genomic matches are found by querying with a reduced sequence corresponding to the final 17mer of the 20mer guide target sequence, combined with the `GG` of the PAM sequence. Mismatches are assessed within this set of bases only, for a total of 19 possible matching bases. |
CFD Score[?]Off target matches are assesed via a Cutting Frequency Determination, or CFD score. This value provides an estimate of how specific mismatches affect the likelihood that an sgRNA will cut a given target sequence. For more information, see Doench, Fusi et al., Nature Biotechnology 2016. |
Match Tier[?]For a description of CRISPR match tiers, see How the sgRNA Designer Works. |
1 |
NC_000012.12 |
12 |
57951804 |
+ |
ATP23 |
NNNGGCCCATATGAACAGAG |
NGG |
0 |
1.0 |
Tier I |
2 |
NC_000008.11 |
8 |
22920320 |
+ |
PEBP4 |
NNNGGCCCCTATGAAGAGAG |
NGG |
2 |
0.0879 |
Tier I |
3 |
NC_000022.11 |
22 |
39099876 |
+ |
APOBEC3H |
NNNGGCCCAAATGAACAGAA |
NGG |
2 |
0.8036 |
Tier II |
4 |
NC_000011.10 |
11 |
72016559 |
+ |
NUMA1 |
NNNGACCCATGTGAACAGAG |
NGG |
2 |
0.5633 |
Tier II |
5 |
NC_000014.9 |
14 |
32769600 |
- |
AKAP6 |
NNNGGCCAATATGAACAAAG |
NGG |
2 |
0.45 |
Tier II |
6 |
NC_000013.11 |
13 |
46556293 |
+ |
LRCH1 |
NNNAGCCCATCTGAACAGAG |
NGG |
2 |
0.36 |
Tier II |
7 |
NC_000002.12 |
2 |
153680719 |
- |
GALNT13 |
NNNGGGCCATATGGACAGAG |
NGG |
2 |
0.2333 |
Tier II |
8 |
NC_000015.10 |
15 |
25859479 |
+ |
ATP10A |
NNNGGTCCATATGATCAGAG |
NGG |
2 |
0.1857 |
Tier II |
9 |
NC_000004.12 |
4 |
147800368 |
+ |
ARHGAP10 |
NNNGGCCCATGTGACCAGAG |
NGG |
2 |
0.1773 |
Tier II |
10 |
NC_000015.10 |
15 |
43257441 |
+ |
TGM5 |
NNNTGCCCATATGAACAGAG |
NGT |
2 |
0.0059 |
Tier II |
11 |
NC_000011.10 |
11 |
72016559 |
+ |
LOC100128494 |
NNNGACCCATGTGAACAGAG |
NGG |
2 |
0.5633 |
Tier III |
12 |
NC_000023.11 |
X |
39798234 |
+ |
LOC105373177 |
NNNGGACCATAGGAACAGAG |
NGG |
2 |
0.4643 |
Tier III |
13 |
NC_000002.12 |
2 |
95007286 |
- |
MAL-AS1 |
NNNGGCCAATCTGAACAGAG |
NGG |
2 |
0.26 |
Tier III |
Gene matches for this target sequence (CRISPRko, PAM=NGG, mouse):
| Reference Sequence |
Chromosome |
Cut Position |
Match Strand |
Match Gene |
Match Sequence |
PAM Seq. |
Mismatches[?]Genomic matches are found by querying with a reduced sequence corresponding to the final 17mer of the 20mer guide target sequence, combined with the `GG` of the PAM sequence. Mismatches are assessed within this set of bases only, for a total of 19 possible matching bases. |
CFD Score[?]Off target matches are assesed via a Cutting Frequency Determination, or CFD score. This value provides an estimate of how specific mismatches affect the likelihood that an sgRNA will cut a given target sequence. For more information, see Doench, Fusi et al., Nature Biotechnology 2016. |
Match Tier[?]For a description of CRISPR match tiers, see How the sgRNA Designer Works. |
1 |
NC_000076.6 |
10 |
97483425 |
+ |
Dcn |
NNNGGACCATTTGAACAGAG |
NGG |
2 |
0.2857 |
Tier I |
2 |
NC_000085.6 |
19 |
30857565 |
- |
Prkg1 |
NNNGACCCAAATGAACAGAG |
NGG |
2 |
0.7429 |
Tier II |
3 |
NC_000072.6 |
6 |
142147523 |
- |
Slco1a6 |
NNNGGCCAATATGAACAGAG |
NGG |
1 |
0.65 |
Tier II |
4 |
NC_000081.6 |
15 |
95408414 |
- |
Nell2 |
NNNGGCCTATATGAACATAG |
NGG |
2 |
0.5833 |
Tier II |
5 |
NC_000068.7 |
2 |
41603321 |
- |
Lrp1b |
NNNGGCCAATATGAACATAG |
NGG |
2 |
0.4333 |
Tier II |
6 |
NC_000070.6 |
4 |
66210165 |
+ |
Astn2 |
NNNGGCCAATATGAACATAG |
NGG |
2 |
0.4333 |
Tier II |
7 |
NC_000070.6 |
4 |
111277782 |
- |
Agbl4 |
NNNGGCCAATATGAACATAG |
NGG |
2 |
0.4333 |
Tier II |
8 |
NC_000076.6 |
10 |
79526564 |
+ |
Plpp2 |
NNNGGTCCATATGGACAGAG |
NGG |
2 |
0.4333 |
Tier II |
9 |
NC_000072.6 |
6 |
80533928 |
+ |
Lrrtm4 |
NNNGGCCCCTATGAACATAG |
NGG |
2 |
0.381 |
Tier II |
10 |
NC_000086.7 |
X |
129902473 |
+ |
Diaph2 |
NNNGGCCCCTATGAACATAG |
NGG |
2 |
0.381 |
Tier II |
11 |
NC_000079.6 |
13 |
13733320 |
+ |
Lyst |
NNNGGCCACTATGAACAGAG |
NGG |
2 |
0.3714 |
Tier II |
12 |
NC_000082.6 |
16 |
81232105 |
+ |
Ncam2 |
NNNGGCCACTATGAACAGAG |
NGG |
2 |
0.3714 |
Tier II |
13 |
NC_000084.6 |
18 |
7385623 |
- |
Mpp7 |
NNNGGCCACTATGAACAGAG |
NGG |
2 |
0.3714 |
Tier II |
14 |
NC_000075.6 |
9 |
100883966 |
+ |
Stag1 |
NNNGGCCGCTATGAACAGAG |
NGG |
2 |
0.3673 |
Tier II |
15 |
NC_000070.6 |
4 |
155290081 |
- |
Prkcz |
NNNGGCCCATGTGTACAGAG |
NGG |
2 |
0.3467 |
Tier II |
16 |
NC_000073.6 |
7 |
140255865 |
- |
5830411N06Rik |
NNNGGCCAATATGAACACAG |
NGG |
2 |
0.3095 |
Tier II |
17 |
NC_000077.6 |
11 |
43570330 |
+ |
Ccnjl |
NNNGGCCCATAGGAACAGTG |
NGG |
2 |
0.2692 |
Tier II |
18 |
NC_000077.6 |
11 |
103840500 |
- |
Nsf |
NNNGCCCCATATGAACAGAG |
NAG |
2 |
0.2037 |
Tier II |
19 |
NC_000075.6 |
9 |
68716609 |
- |
Rora |
NNNTGCCCATATGTACAGAG |
NGG |
2 |
0.1939 |
Tier II |
20 |
NC_000079.6 |
13 |
51458878 |
- |
Shc3 |
NNNGGCCCATATGAACAGAG |
NTA |
2 |
0.0 |
Tier II |
21 |
NC_000069.6 |
3 |
159205101 |
- |
Gm20752 |
NNNGGCTCCTATGAACAGAG |
NGG |
2 |
0.4643 |
Tier III |
22 |
NC_000067.6 |
1 |
79024393 |
- |
Gm29536 |
NNNGGCCCCTATGAACATAG |
NGG |
2 |
0.381 |
Tier III |
23 |
NC_000071.6 |
5 |
28641061 |
+ |
9530036O11Rik |
NNNTGCCAATATGAACAGAG |
NGG |
2 |
0.2364 |
Tier III |
24 |
NC_000074.6 |
8 |
92003997 |
- |
Gm36843 |
NNNGCCCCATATTAACAGAG |
NGG |
2 |
0.2357 |
Tier III |
Other clones with same target sequence:
(none)