Construct: sgRNA BRDN0001145988
Construct Description:
- Construct Type:
- sgRNA
- Other Identifiers:
- n/a
- DNA Barcode:
- GAAGGGCAAGTGTCTCCTAG
Original Target:
- Taxon:
-
Homo sapiens (human)
- Gene:
- TAF1L (138474)
- Gene Description:
- n/a
- CRISPR Mechanism
- CRISPRko
Vector Information:
- Vector Backbone:
- pXPR_003
- Pol II Cassette 1:
- EF1A-PuroR
- Pol II Cassette 2:
- n/a
- Selection Marker:
- PuroR
- Visible Reporter:
- n/a
- Epitope Tag:
- n/a
Additional Information:
- Addgene ID:
- 77120
Gene matches for this target sequence (CRISPRko, PAM=NGG, human):
| Reference Sequence |
Chromosome |
Cut Position |
Match Strand |
Match Gene |
Match Sequence |
PAM Seq. |
Mismatches[?]Genomic matches are found by querying with a reduced sequence corresponding to the final 17mer of the 20mer guide target sequence, combined with the `GG` of the PAM sequence. Mismatches are assessed within this set of bases only, for a total of 19 possible matching bases. |
CFD Score[?]Off target matches are assesed via a Cutting Frequency Determination, or CFD score. This value provides an estimate of how specific mismatches affect the likelihood that an sgRNA will cut a given target sequence. For more information, see Doench, Fusi et al., Nature Biotechnology 2016. |
Match Tier[?]For a description of CRISPR match tiers, see How the sgRNA Designer Works. |
1 |
NC_000009.12 |
9 |
32632681 |
- |
TAF1L |
NNNGGGCAAGTGTCTCCTAG |
NGG |
0 |
1.0 |
Tier I |
2 |
NC_000023.11 |
X |
71392633 |
+ |
TAF1 |
NNNGGGCAAGTGTCTGCTAG |
NGG |
1 |
0.1538 |
Tier I |
3 |
NC_000010.11 |
10 |
18002244 |
- |
SLC39A12 |
NNNGGGCAAGCGTTTCCTAG |
NGG |
2 |
0.4889 |
Tier II |
4 |
NC_000019.10 |
19 |
17083533 |
+ |
MYO9B |
NNNGGCCAAGTGTCTCCTGG |
NGG |
2 |
0.2557 |
Tier II |
5 |
NC_000022.11 |
22 |
46526624 |
- |
CELSR1 |
NNNGGGCGAGTGTCTCCGAG |
NGG |
2 |
0.2444 |
Tier II |
6 |
NC_000001.11 |
1 |
44339800 |
- |
ERI3 |
NNNGGGCAAATGGCTCCTAG |
NGG |
2 |
0.2435 |
Tier II |
7 |
NC_000003.12 |
3 |
183151308 |
+ |
LAMP3 |
NNNGGGCAAGTCTCTCCCAG |
NGG |
2 |
0.2269 |
Tier II |
8 |
NC_000008.11 |
8 |
103206743 |
+ |
BAALC |
NNNGTGCAAGTGACTCCTAG |
NGG |
2 |
0.2077 |
Tier II |
9 |
NC_000017.11 |
17 |
80029438 |
- |
TBC1D16 |
NNNGGCCAAGTGGCTCCTAG |
NGG |
2 |
0.1779 |
Tier II |
10 |
NC_000018.10 |
18 |
28115498 |
+ |
CDH2 |
NNNGGGCAACTGTCTCCTAC |
NGG |
2 |
0.1714 |
Tier II |
11 |
NC_000023.11 |
X |
153960995 |
- |
HCFC1 |
NNNGTGCAAGTGTATCCTAG |
NGG |
2 |
0.105 |
Tier II |
12 |
NC_000020.11 |
20 |
59630042 |
+ |
PHACTR3 |
NNNGGGCAAGTGTGTCCTGG |
NGG |
2 |
0.0 |
Tier II |
13 |
NC_000010.11 |
10 |
18002244 |
- |
SLC39A12-AS1 |
NNNGGGCAAGCGTTTCCTAG |
NGG |
2 |
0.4889 |
Tier III |
14 |
NC_000002.12 |
2 |
15717616 |
+ |
LINC01804 |
NNNGGGCAAGTGTCTCCCAT |
NGG |
2 |
0.3 |
Tier III |
Gene matches for this target sequence (CRISPRko, PAM=NGG, mouse):
| Reference Sequence |
Chromosome |
Cut Position |
Match Strand |
Match Gene |
Match Sequence |
PAM Seq. |
Mismatches[?]Genomic matches are found by querying with a reduced sequence corresponding to the final 17mer of the 20mer guide target sequence, combined with the `GG` of the PAM sequence. Mismatches are assessed within this set of bases only, for a total of 19 possible matching bases. |
CFD Score[?]Off target matches are assesed via a Cutting Frequency Determination, or CFD score. This value provides an estimate of how specific mismatches affect the likelihood that an sgRNA will cut a given target sequence. For more information, see Doench, Fusi et al., Nature Biotechnology 2016. |
Match Tier[?]For a description of CRISPR match tiers, see How the sgRNA Designer Works. |
1 |
NC_000084.6 |
18 |
38281306 |
- |
Pcdh12 |
NNNGGCAAAGTGTCTCCTAG |
NGG |
2 |
0.5114 |
Tier I |
2 |
NC_000086.7 |
X |
101556586 |
+ |
Taf1 |
NNNGGGCAAATGTCTCCTGG |
NGG |
2 |
0.35 |
Tier I |
3 |
NC_000078.6 |
12 |
71840413 |
+ |
Daam1 |
NNNAGCCAAGTGTCTCCTAG |
NGG |
2 |
0.6136 |
Tier II |
4 |
NC_000084.6 |
18 |
38281306 |
- |
Rnf14 |
NNNGGCAAAGTGTCTCCTAG |
NGG |
2 |
0.5114 |
Tier II |
5 |
NC_000070.6 |
4 |
85863930 |
- |
Adamtsl1 |
NNNGGGCAAGTCTCTCCTAT |
NGG |
2 |
0.3706 |
Tier II |
6 |
NC_000073.6 |
7 |
127485291 |
+ |
Fbrs |
NNNGGGAAAGTGTCTCCTAC |
NGG |
2 |
0.3214 |
Tier II |
7 |
NC_000070.6 |
4 |
137724011 |
- |
Rap1gap |
NNNGGGCCAGAGTCTCCTAG |
NGG |
2 |
0.3214 |
Tier II |
8 |
NC_000070.6 |
4 |
36014936 |
+ |
Lingo2 |
NNNGGGCAAGTGTTTCCCAG |
NGG |
2 |
0.3143 |
Tier II |
9 |
NC_000071.6 |
5 |
123702257 |
- |
Zcchc8 |
NNNGGGCAGGTGTCTCCCAG |
NGG |
2 |
0.2857 |
Tier II |
10 |
NC_000074.6 |
8 |
121786523 |
- |
Jph3 |
NNNGGGCAAGTGACTCCTGG |
NGG |
2 |
0.2596 |
Tier II |
11 |
NC_000080.6 |
14 |
65390239 |
+ |
Zfp395 |
NNNGGGCAGGTGTCTCCTAG |
NAG |
2 |
0.1728 |
Tier II |
12 |
NC_000076.6 |
10 |
76293053 |
+ |
Dip2a |
NNNGGGCAAGTGTCTCCTAA |
NGA |
2 |
0.0651 |
Tier II |
13 |
NC_000083.6 |
17 |
5720993 |
+ |
Zdhhc14 |
NNNGGGCATGTGTCTCCTAG |
NCG |
2 |
0.0643 |
Tier II |
14 |
NC_000077.6 |
11 |
115234004 |
+ |
Tmem104 |
NNNGGGCAAGAGTCTCCTAG |
NGA |
2 |
0.0521 |
Tier II |
15 |
NC_000068.7 |
2 |
27752467 |
+ |
Rxra |
NNNGGGCAAGTGGCTGCTAG |
NGG |
2 |
0.0401 |
Tier II |
16 |
NC_000076.6 |
10 |
127207339 |
+ |
Pip4k2c |
NNNGGGCAAGTGTCTCCGAG |
NGA |
2 |
0.0231 |
Tier II |
17 |
NC_000068.7 |
2 |
29890453 |
- |
Odf2 |
NNNGGGCAACTGTCTCCTAG |
NTG |
2 |
0.0156 |
Tier II |
18 |
NC_000081.6 |
15 |
89189803 |
- |
Dennd6b |
NNNGGGCAAGTGCCTCCTAG |
NGT |
2 |
0.0127 |
Tier II |
19 |
NC_000077.6 |
11 |
36662177 |
- |
Tenm2 |
NNNGGCCAAGTGTCTCCTAG |
NGT |
2 |
0.011 |
Tier II |
20 |
NC_000077.6 |
11 |
33773005 |
- |
Kcnip1 |
NNNGGGCAAGTGTCTCCTTG |
NGT |
2 |
0.0087 |
Tier II |
21 |
NC_000083.6 |
17 |
14205952 |
+ |
Gm34510 |
NNNGGGCAAGTGTCTCCAAA |
NGG |
2 |
0.625 |
Tier III |
22 |
NC_000080.6 |
14 |
48737198 |
- |
Otx2os1 |
NNNGGGTAAGTGTTTCCTAG |
NGG |
2 |
0.5958 |
Tier III |
23 |
NC_000068.7 |
2 |
122715963 |
- |
4930417H01Rik |
NNNGGGCATGTGCCTCCTAG |
NGG |
2 |
0.4737 |
Tier III |
24 |
NC_000067.6 |
1 |
73724816 |
- |
6030407O03Rik |
NNNGGTCAAGTGTCTCCTAC |
NGG |
2 |
0.2857 |
Tier III |
25 |
NC_000080.6 |
14 |
24865766 |
- |
Gm32008 |
NNNGGGCAGGGGTCTCCTAG |
NGG |
2 |
0.2667 |
Tier III |
Other clones with same target sequence:
(none)