Construct: sgRNA BRDN0001146002
Construct Description:
- Construct Type:
- sgRNA
- Other Identifiers:
- n/a
- DNA Barcode:
- CTTATGTCAGGTTATTCACA
Original Target:
- Taxon:
-
Homo sapiens (human)
- Gene:
- MAPK9 (5601)
- Gene Description:
- n/a
- CRISPR Mechanism
- CRISPRko
Vector Information:
- Vector Backbone:
- pXPR_003
- Pol II Cassette 1:
- EF1A-PuroR
- Pol II Cassette 2:
- n/a
- Selection Marker:
- PuroR
- Visible Reporter:
- n/a
- Epitope Tag:
- n/a
Additional Information:
- Addgene ID:
- 76719
Gene matches for this target sequence (CRISPRko, PAM=NGG, human):
Gene matches for this target sequence (CRISPRko, PAM=NGG, mouse):
| Reference Sequence |
Chromosome |
Cut Position |
Match Strand |
Match Gene |
Match Sequence |
PAM Seq. |
Mismatches[?]Genomic matches are found by querying with a reduced sequence corresponding to the final 17mer of the 20mer guide target sequence, combined with the `GG` of the PAM sequence. Mismatches are assessed within this set of bases only, for a total of 19 possible matching bases. |
CFD Score[?]Off target matches are assesed via a Cutting Frequency Determination, or CFD score. This value provides an estimate of how specific mismatches affect the likelihood that an sgRNA will cut a given target sequence. For more information, see Doench, Fusi et al., Nature Biotechnology 2016. |
Match Tier[?]For a description of CRISPR match tiers, see How the sgRNA Designer Works. |
1 |
NC_000077.6 |
11 |
49869219 |
+ |
Mapk9 |
NNNATGTCAGGTTATTCATA |
NGG |
1 |
0.4615 |
Tier I |
2 |
NC_000075.6 |
9 |
105259065 |
- |
Nek11 |
NNNATGTTAGGTTATACACA |
NGG |
2 |
0.7955 |
Tier II |
3 |
NC_000075.6 |
9 |
59410790 |
+ |
Arih1 |
NNNATGTGAGATTATTCACA |
NGG |
2 |
0.6429 |
Tier II |
4 |
NC_000081.6 |
15 |
31269236 |
- |
Dap |
NNNATCTCAGGATATTCACA |
NGG |
2 |
0.5455 |
Tier II |
5 |
NC_000067.6 |
1 |
126184450 |
+ |
Nckap5 |
NNNATATCAGGTTATTCAAA |
NGG |
2 |
0.4286 |
Tier II |
6 |
NC_000068.7 |
2 |
69007010 |
- |
Cers6 |
NNNATGTCAGGATTTTCACA |
NGG |
2 |
0.4267 |
Tier II |
7 |
NC_000072.6 |
6 |
28301833 |
+ |
Zfp800 |
NNNATGTCATGGTATTCACA |
NGG |
2 |
0.4063 |
Tier II |
8 |
NC_000082.6 |
16 |
74726841 |
+ |
Robo2 |
NNNATGTCATGTTATTTACA |
NGG |
2 |
0.3792 |
Tier II |
9 |
NC_000067.6 |
1 |
21456889 |
+ |
Kcnq5 |
NNNATTTCAGGTTATTCTCA |
NGG |
2 |
0.3333 |
Tier II |
10 |
NC_000077.6 |
11 |
52769767 |
- |
Fstl4 |
NNNATGTCATTTTATTCACA |
NGG |
2 |
0.3125 |
Tier II |
11 |
NC_000067.6 |
1 |
191732842 |
+ |
Lpgat1 |
NNNATGTCAGGGTAATCACA |
NGG |
2 |
0.2895 |
Tier II |
12 |
NC_000074.6 |
8 |
36237325 |
- |
Lonrf1 |
NNNATGTCTGGTTATTCAAA |
NGG |
2 |
0.2571 |
Tier II |
13 |
NC_000085.6 |
19 |
6073805 |
+ |
Vps51 |
NNNATGTCATGTTACTCACA |
NGG |
2 |
0.2216 |
Tier II |
14 |
NC_000074.6 |
8 |
104172258 |
- |
Bean1 |
NNNATGTCAGGAGATTCACA |
NGG |
2 |
0.2087 |
Tier II |
15 |
NC_000086.7 |
X |
162524304 |
- |
Reps2 |
NNNATGTCAGGTGTTTCACA |
NGG |
2 |
0.1391 |
Tier II |
16 |
NC_000081.6 |
15 |
30561852 |
+ |
Ctnnd2 |
NNNATGCCAGGTTATTGACA |
NGG |
2 |
0.0404 |
Tier II |
17 |
NC_000081.6 |
15 |
36559989 |
- |
Snx31 |
NNNATCTCAGGTTATTGACA |
NGG |
2 |
0.0401 |
Tier II |
18 |
NC_000079.6 |
13 |
9579054 |
- |
Dip2c |
NNNATGTCAGGTTATTCAGA |
NAG |
2 |
0.0324 |
Tier II |
19 |
NC_000067.6 |
1 |
100332485 |
+ |
Cntnap5b |
NNNATGTCAGGTCATTCACA |
NTG |
2 |
0.0308 |
Tier II |
20 |
NC_000085.6 |
19 |
47781828 |
+ |
Cfap43 |
NNNATGTCACGTTATTGACA |
NGG |
2 |
0.0235 |
Tier II |
21 |
NC_000073.6 |
7 |
97217192 |
+ |
Gab2 |
NNNATGTCAGGTTATTTACA |
NTG |
2 |
0.0182 |
Tier II |
22 |
NC_000067.6 |
1 |
174223166 |
- |
Spta1 |
NNNATGTCAGGTTATTCATA |
NGC |
2 |
0.0103 |
Tier II |
23 |
NC_000081.6 |
15 |
79625125 |
+ |
Fam227a |
NNNATGTCAGGTGATTCACA |
NTG |
2 |
0.0102 |
Tier II |
24 |
NC_000085.6 |
19 |
43377906 |
- |
Hpse2 |
NNNCTGTCAGGTTATTCACA |
NGT |
2 |
0.0057 |
Tier II |
25 |
NC_000069.6 |
3 |
76645808 |
+ |
Fstl5 |
NNNATGTCAGGTTATTCACA |
NTT |
2 |
0.0 |
Tier II |
26 |
NC_000068.7 |
2 |
132216977 |
- |
Gm14051 |
NNNTTGTCAGGTTATTCACT |
NGG |
2 |
0.3818 |
Tier III |
Other clones with same target sequence:
(none)