Construct: sgRNA BRDN0001146112
Construct Description:
- Construct Type:
- sgRNA
- Other Identifiers:
- n/a
- DNA Barcode:
- AAAAAGCTTTCTGCTAGGGG
Original Target:
- Taxon:
-
Homo sapiens (human)
- Gene:
- CAMK2D (817)
- Gene Description:
- n/a
- CRISPR Mechanism
- CRISPRko
Vector Information:
- Vector Backbone:
- pXPR_003
- Pol II Cassette 1:
- EF1A-PuroR
- Pol II Cassette 2:
- n/a
- Selection Marker:
- PuroR
- Visible Reporter:
- n/a
- Epitope Tag:
- n/a
Additional Information:
- Addgene ID:
- 77185
Gene matches for this target sequence (CRISPRko, PAM=NGG, human):
Gene matches for this target sequence (CRISPRko, PAM=NGG, mouse):
| Reference Sequence |
Chromosome |
Cut Position |
Match Strand |
Match Gene |
Match Sequence |
PAM Seq. |
Mismatches[?]Genomic matches are found by querying with a reduced sequence corresponding to the final 17mer of the 20mer guide target sequence, combined with the `GG` of the PAM sequence. Mismatches are assessed within this set of bases only, for a total of 19 possible matching bases. |
CFD Score[?]Off target matches are assesed via a Cutting Frequency Determination, or CFD score. This value provides an estimate of how specific mismatches affect the likelihood that an sgRNA will cut a given target sequence. For more information, see Doench, Fusi et al., Nature Biotechnology 2016. |
Match Tier[?]For a description of CRISPR match tiers, see How the sgRNA Designer Works. |
1 |
NC_000069.6 |
3 |
126599159 |
+ |
Camk2d |
NNNAAGCTTTCTGCTAGGGG |
NGG |
0 |
1.0 |
Tier I |
2 |
NC_000080.6 |
14 |
24135574 |
+ |
Dlg5 |
NNNGAGCTTTCTGCTAGGGT |
NGG |
2 |
0.4375 |
Tier I |
3 |
NC_000077.6 |
11 |
67598745 |
- |
Gas7 |
NNNAAGCTTCCTGCTAGGGG |
NGG |
1 |
0.5333 |
Tier II |
4 |
NC_000083.6 |
17 |
47151829 |
+ |
Trerf1 |
NNNAAGCTCTCGGCTAGGGG |
NGG |
2 |
0.4615 |
Tier II |
5 |
NC_000083.6 |
17 |
46506923 |
- |
Cul9 |
NNNAGGCTGTCTGCTAGGGG |
NGG |
2 |
0.4457 |
Tier II |
6 |
NC_000077.6 |
11 |
95267008 |
- |
Tac4 |
NNNAAGCTGTCTGCTAGGGT |
NGG |
2 |
0.4333 |
Tier II |
7 |
NC_000076.6 |
10 |
80261447 |
+ |
Dazap1 |
NNNCAGCCTTCTGCTAGGGG |
NGG |
2 |
0.3529 |
Tier II |
8 |
NC_000073.6 |
7 |
18482084 |
- |
Psg26 |
NNNAAGCTTTGTGCTAGGGG |
NGG |
1 |
0.25 |
Tier II |
9 |
NC_000067.6 |
1 |
87478809 |
+ |
Ngef |
NNNAAGCTTCCTCCTAGGGG |
NGG |
2 |
0.2246 |
Tier II |
10 |
NC_000082.6 |
16 |
34383466 |
- |
Kalrn |
NNNAAGATTTCTGCTGGGGG |
NGG |
2 |
0.1442 |
Tier II |
11 |
NC_000072.6 |
6 |
23500278 |
+ |
Cadps2 |
NNNAAGGTTTGTGCTAGGGG |
NGG |
2 |
0.1176 |
Tier II |
12 |
NC_000073.6 |
7 |
18352900 |
- |
Psg18 |
NNNAAGCTTTGTGCTAGGGC |
NGG |
2 |
0.1071 |
Tier II |
13 |
NC_000073.6 |
7 |
18429966 |
- |
Psg28 |
NNNAAGCTTTGTGCTAGGGC |
NGG |
2 |
0.1071 |
Tier II |
14 |
NC_000075.6 |
9 |
58107939 |
+ |
Stra6 |
NNNAAGCTTTCTTCTGGGGG |
NGG |
2 |
0.0577 |
Tier II |
15 |
NC_000075.6 |
9 |
58107939 |
+ |
Ccdc33 |
NNNAAGCTTTCTTCTGGGGG |
NGG |
2 |
0.0577 |
Tier II |
16 |
NC_000083.6 |
17 |
67142724 |
- |
Ptprm |
NNNAAGCTTTCTGCTGTGGG |
NGG |
2 |
0.0481 |
Tier II |
17 |
NC_000068.7 |
2 |
6799966 |
- |
Celf2 |
NNNAAGCCTTCTGCTAGGGG |
NTG |
2 |
0.039 |
Tier II |
18 |
NC_000083.6 |
17 |
24857331 |
- |
Hagh |
NNNATGCTTTCTGCTAGGGG |
NTG |
2 |
0.0142 |
Tier II |
19 |
NC_000070.6 |
4 |
132649415 |
- |
Eya3 |
NNNAAGCTTTCTGCTGGGGG |
NTG |
2 |
0.0075 |
Tier II |
20 |
NC_000070.6 |
4 |
119851869 |
+ |
Hivep3 |
NNNAAGATTTCTGCTTGGGG |
NGG |
2 |
0.0 |
Tier II |
21 |
NC_000071.6 |
5 |
128064142 |
- |
Tmem132d |
NNNAAGCTTTCTGCTTGGGA |
NGG |
2 |
0.0 |
Tier II |
22 |
NC_000073.6 |
7 |
101993060 |
+ |
Numa1 |
NNNAAGCTTTCTGGTAGGGG |
NAG |
2 |
0.0 |
Tier II |
23 |
NC_000078.6 |
12 |
37940514 |
- |
Dgkb |
NNNAAGCTTTCTGTTTGGGG |
NGG |
2 |
0.0 |
Tier II |
24 |
NC_000073.6 |
7 |
138588223 |
- |
Gm30751 |
NNNAATCTTTCTGCTAGGGT |
NGG |
2 |
0.4667 |
Tier III |
25 |
NC_000079.6 |
13 |
23153536 |
- |
Vmn1r-ps129 |
NNNAAGCTTTCTCCAAGGGG |
NGG |
2 |
0.2438 |
Tier III |
26 |
NC_000085.6 |
19 |
38316401 |
- |
Gm9886 |
NNNAAGCTTTCTGCTGGGAG |
NGG |
2 |
0.1374 |
Tier III |
27 |
NC_000081.6 |
15 |
87127581 |
- |
A930027H12Rik |
NNNATGCTTTCTGCTGGGGG |
NGG |
2 |
0.0699 |
Tier III |
28 |
NC_000075.6 |
9 |
21154029 |
- |
Gm35977 |
NNNAAGCTTTCTGCTCTGGG |
NGG |
2 |
0.0 |
Tier III |
Other clones with same target sequence:
(none)