Construct: sgRNA BRDN0001146353
Construct Description:
- Construct Type:
- sgRNA
- Other Identifiers:
- n/a
- DNA Barcode:
- TTTGTGAAAGGTTTATACAG
Original Target:
- Taxon:
-
Homo sapiens (human)
- Gene:
- PPIP5K2 (23262)
- Gene Description:
- n/a
- CRISPR Mechanism
- CRISPRko
Vector Information:
- Vector Backbone:
- pXPR_003
- Pol II Cassette 1:
- EF1A-PuroR
- Pol II Cassette 2:
- n/a
- Selection Marker:
- PuroR
- Visible Reporter:
- n/a
- Epitope Tag:
- n/a
Additional Information:
- Addgene ID:
- 76340
Gene matches for this target sequence (CRISPRko, PAM=NGG, human):
| Reference Sequence |
Chromosome |
Cut Position |
Match Strand |
Match Gene |
Match Sequence |
PAM Seq. |
Mismatches[?]Genomic matches are found by querying with a reduced sequence corresponding to the final 17mer of the 20mer guide target sequence, combined with the `GG` of the PAM sequence. Mismatches are assessed within this set of bases only, for a total of 19 possible matching bases. |
CFD Score[?]Off target matches are assesed via a Cutting Frequency Determination, or CFD score. This value provides an estimate of how specific mismatches affect the likelihood that an sgRNA will cut a given target sequence. For more information, see Doench, Fusi et al., Nature Biotechnology 2016. |
Match Tier[?]For a description of CRISPR match tiers, see How the sgRNA Designer Works. |
1 |
NC_000005.10 |
5 |
103149159 |
+ |
PPIP5K2 |
NNNGTGAAAGGTTTATACAG |
NGG |
0 |
1.0 |
Tier I |
2 |
NC_000020.11 |
20 |
45096758 |
- |
KCNS1 |
NNNGTGAGAGGTTTAAACAG |
NGG |
2 |
0.6667 |
Tier II |
3 |
NC_000004.12 |
4 |
16876849 |
- |
LDB2 |
NNNGTTAAAGGTTTATACAA |
NGG |
2 |
0.625 |
Tier II |
4 |
NC_000013.11 |
13 |
41228727 |
- |
MTRF1 |
NNNGTTAAATGTTTATACAG |
NGG |
2 |
0.5417 |
Tier II |
5 |
NC_000023.11 |
X |
105888029 |
+ |
NRK |
NNNGTGAAAATTTTATACAG |
NGG |
2 |
0.359 |
Tier II |
6 |
NC_000007.14 |
7 |
135383328 |
- |
CNOT4 |
NNNGTGAAAGATTTAGACAG |
NGG |
2 |
0.3462 |
Tier II |
7 |
NC_000010.11 |
10 |
86868061 |
+ |
BMPR1A |
NNNGTGGAAGTTTTATACAG |
NGG |
2 |
0.2715 |
Tier II |
8 |
NC_000001.11 |
1 |
202420412 |
+ |
PPP1R12B |
NNNGTGAAAGGTTTCTACAA |
NGG |
2 |
0.2557 |
Tier II |
9 |
NC_000001.11 |
1 |
51628142 |
+ |
OSBPL9 |
NNNGTGAAAGGTCTATACAG |
NAG |
2 |
0.2047 |
Tier II |
10 |
NC_000008.11 |
8 |
89974654 |
+ |
NBN |
NNNGTGAAAGGTACATACAG |
NGG |
2 |
0.1978 |
Tier II |
11 |
NC_000006.12 |
6 |
65323853 |
- |
EYS |
NNNGTGAAAGGTTTAAGCAG |
NGG |
2 |
0.1604 |
Tier II |
12 |
NC_000001.11 |
1 |
108971709 |
+ |
WDR47 |
NNNTTGAAAGGTTTATACAG |
NGA |
2 |
0.0253 |
Tier II |
13 |
NC_000003.12 |
3 |
42579957 |
+ |
SEC22C |
NNNGAGAAAGGTTTATACAG |
NTG |
2 |
0.0195 |
Tier II |
14 |
NC_000003.12 |
3 |
19489004 |
+ |
KCNH8 |
NNNGTGAAAGGTTGATACAA |
NGG |
2 |
0.0 |
Tier II |
15 |
NC_000001.11 |
1 |
67729547 |
- |
GNG12 |
NNNGTGAAAGGTTGATGCAG |
NGG |
2 |
0.0 |
Tier II |
16 |
NC_000007.14 |
7 |
7891441 |
+ |
LOC124901586 |
NNNGTGAAATGTTTATACAA |
NGG |
2 |
0.7617 |
Tier III |
17 |
NC_000013.11 |
13 |
41228727 |
- |
KBTBD6-DT |
NNNGTTAAATGTTTATACAG |
NGG |
2 |
0.5417 |
Tier III |
18 |
NC_000001.11 |
1 |
50304541 |
+ |
LINC02808 |
NNNTTGAAAAGTTTATACAG |
NGG |
2 |
0.3394 |
Tier III |
19 |
NC_000008.11 |
8 |
104887179 |
- |
LOC105375694 |
NNNGTGAAATGTTTATTCAG |
NGG |
2 |
0.1083 |
Tier III |
20 |
NC_000020.11 |
20 |
35558760 |
+ |
FER1L4 |
NNNGTGATAGGTTTATTCAG |
NGG |
2 |
0.0571 |
Tier III |
Gene matches for this target sequence (CRISPRko, PAM=NGG, mouse):
| Reference Sequence |
Chromosome |
Cut Position |
Match Strand |
Match Gene |
Match Sequence |
PAM Seq. |
Mismatches[?]Genomic matches are found by querying with a reduced sequence corresponding to the final 17mer of the 20mer guide target sequence, combined with the `GG` of the PAM sequence. Mismatches are assessed within this set of bases only, for a total of 19 possible matching bases. |
CFD Score[?]Off target matches are assesed via a Cutting Frequency Determination, or CFD score. This value provides an estimate of how specific mismatches affect the likelihood that an sgRNA will cut a given target sequence. For more information, see Doench, Fusi et al., Nature Biotechnology 2016. |
Match Tier[?]For a description of CRISPR match tiers, see How the sgRNA Designer Works. |
1 |
NC_000067.6 |
1 |
156078902 |
+ |
Fam163a |
NNNGTGAAAGGATTATACAT |
NGG |
2 |
0.56 |
Tier I |
2 |
NC_000067.6 |
1 |
97750722 |
- |
Ppip5k2 |
NNNATGAAAGGTTTATACCG |
NGG |
2 |
0.1862 |
Tier I |
3 |
NC_000074.6 |
8 |
111170537 |
+ |
Glg1 |
NNNGGGAAAGGTTTATACAA |
NGG |
2 |
0.6 |
Tier II |
4 |
NC_000068.7 |
2 |
76113356 |
- |
Pde11a |
NNNGTGAAAGGATTACACAG |
NGG |
2 |
0.5333 |
Tier II |
5 |
NC_000080.6 |
14 |
21241762 |
+ |
Adk |
NNNGTGTAAGGCTTATACAG |
NGG |
2 |
0.4145 |
Tier II |
6 |
NC_000072.6 |
6 |
46435191 |
- |
Cntnap2 |
NNNATGTAAGGTTTATACAG |
NGG |
2 |
0.3938 |
Tier II |
7 |
NC_000068.7 |
2 |
44740129 |
+ |
Gtdc1 |
NNNGTGAAAGGGTTATACAT |
NGG |
2 |
0.35 |
Tier II |
8 |
NC_000068.7 |
2 |
72184609 |
+ |
Rapgef4 |
NNNGTGAAAGGTTTAGACAT |
NGG |
2 |
0.2423 |
Tier II |
9 |
NC_000069.6 |
3 |
157299261 |
- |
Negr1 |
NNNGTTAAAGGTTTAGACAG |
NGG |
2 |
0.2308 |
Tier II |
10 |
NC_000067.6 |
1 |
64080218 |
- |
Klf7 |
NNNGTGAAAGGTTTATGCTG |
NGG |
2 |
0.095 |
Tier II |
11 |
NC_000081.6 |
15 |
64120539 |
- |
Asap1 |
NNNGTGAAAGGTTTGTACAG |
NGA |
2 |
0.0451 |
Tier II |
12 |
NC_000077.6 |
11 |
32352481 |
+ |
Sh3pxd2b |
NNNGTGAAAGGTTTATACAT |
NTG |
2 |
0.0273 |
Tier II |
13 |
NC_000072.6 |
6 |
98987348 |
- |
Foxp1 |
NNNGAGAAAGGTTTATACAG |
NGC |
2 |
0.0111 |
Tier II |
14 |
NC_000083.6 |
17 |
56981262 |
+ |
Acer1 |
NNNGTGAAAGGTTTCTACAG |
NGT |
2 |
0.0044 |
Tier II |
15 |
NC_000070.6 |
4 |
80587989 |
+ |
Gm32658 |
NNNGAGAAAGGATTATACAG |
NGG |
2 |
0.4 |
Tier III |
16 |
NC_000067.6 |
1 |
64080218 |
- |
Gm13748 |
NNNGTGAAAGGTTTATGCTG |
NGG |
2 |
0.095 |
Tier III |
17 |
NC_000084.6 |
18 |
51565103 |
+ |
Gm41722 |
NNNGTGAAAGCTTTATACAG |
NGA |
2 |
0.0298 |
Tier III |
Other clones with same target sequence:
(none)