Construct: sgRNA BRDN0001146403
Construct Description:
- Construct Type:
- sgRNA
- Other Identifiers:
- n/a
- DNA Barcode:
- GTACCTCTGAAGATACTCCA
Original Target:
- Taxon:
-
Homo sapiens (human)
- Gene:
- STK32B (55351)
- Gene Description:
- n/a
- CRISPR Mechanism
- CRISPRko
Vector Information:
- Vector Backbone:
- pXPR_003
- Pol II Cassette 1:
- EF1A-PuroR
- Pol II Cassette 2:
- n/a
- Selection Marker:
- PuroR
- Visible Reporter:
- n/a
- Epitope Tag:
- n/a
Additional Information:
- Addgene ID:
- 76373
Gene matches for this target sequence (CRISPRko, PAM=NGG, human):
| Reference Sequence |
Chromosome |
Cut Position |
Match Strand |
Match Gene |
Match Sequence |
PAM Seq. |
Mismatches[?]Genomic matches are found by querying with a reduced sequence corresponding to the final 17mer of the 20mer guide target sequence, combined with the `GG` of the PAM sequence. Mismatches are assessed within this set of bases only, for a total of 19 possible matching bases. |
CFD Score[?]Off target matches are assesed via a Cutting Frequency Determination, or CFD score. This value provides an estimate of how specific mismatches affect the likelihood that an sgRNA will cut a given target sequence. For more information, see Doench, Fusi et al., Nature Biotechnology 2016. |
Match Tier[?]For a description of CRISPR match tiers, see How the sgRNA Designer Works. |
1 |
NC_000004.12 |
4 |
5331363 |
- |
STK32B |
NNNCCTCTGAAGATACTCCA |
NGG |
0 |
1.0 |
Tier I |
2 |
NC_000002.12 |
2 |
233139871 |
- |
INPP5D |
NNNCCTCTGCAGAGACTCCA |
NGG |
2 |
0.0 |
Tier I |
3 |
NC_000015.10 |
15 |
31693946 |
+ |
OTUD7A |
NNNCCTCTGAAGATGCTCCA |
NGG |
1 |
0.65 |
Tier II |
4 |
NC_000010.11 |
10 |
104813712 |
+ |
SORCS3 |
NNNCCACTGAAGATGCTCCA |
NGG |
2 |
0.5633 |
Tier II |
5 |
NC_000015.10 |
15 |
74333378 |
+ |
CCDC33 |
NNNCCTCTGAAGATGCTTCA |
NGG |
2 |
0.4179 |
Tier II |
6 |
NC_000001.11 |
1 |
156194513 |
- |
SLC25A44 |
NNNCCTCTCAAGATACTCCG |
NGG |
2 |
0.4118 |
Tier II |
7 |
NC_000008.11 |
8 |
31645926 |
+ |
NRG1 |
NNNCCTATGAAGATACTACA |
NGG |
2 |
0.4038 |
Tier II |
8 |
NC_000003.12 |
3 |
68012893 |
+ |
TAFA1 |
NNNCTTCTGAAGATACTCCT |
NGG |
2 |
0.3818 |
Tier II |
9 |
NC_000009.12 |
9 |
28889044 |
- |
LINGO2 |
NNNCTGCTGAAGATACTCCA |
NGG |
2 |
0.3636 |
Tier II |
10 |
NC_000005.10 |
5 |
15792240 |
- |
FBXL7 |
NNNCCTGGGAAGATACTCCA |
NGG |
2 |
0.3451 |
Tier II |
11 |
NC_000001.11 |
1 |
241296036 |
- |
RGS7 |
NNNCTTCTCAAGATACTCCA |
NGG |
2 |
0.3427 |
Tier II |
12 |
NC_000002.12 |
2 |
226789245 |
- |
IRS1 |
NNNCCTCTTAAGAAACTCCA |
NGG |
2 |
0.3302 |
Tier II |
13 |
NC_000006.12 |
6 |
147517716 |
- |
SAMD5 |
NNNCCACTGAAGATACTCCA |
NAG |
2 |
0.2247 |
Tier II |
14 |
NC_000003.12 |
3 |
188679045 |
- |
LPP |
NNNCCTCTGAAGATACCCCA |
NAG |
2 |
0.183 |
Tier II |
15 |
NC_000002.12 |
2 |
219334299 |
- |
RESP18 |
NNNCCTCTGAAGATACTTCA |
NAG |
2 |
0.1667 |
Tier II |
16 |
NC_000004.12 |
4 |
99918636 |
+ |
DNAJB14 |
NNNCCTCTGAAGACACTCAA |
NGG |
2 |
0.1224 |
Tier II |
17 |
NC_000020.11 |
20 |
24634840 |
- |
SYNDIG1 |
NNNCCACTGAAGATACTCCA |
NGA |
2 |
0.0602 |
Tier II |
18 |
NC_000007.14 |
7 |
855345 |
- |
SUN1 |
NNNCCTCTGAAGACACTGCA |
NGG |
2 |
0.0381 |
Tier II |
19 |
NC_000015.10 |
15 |
30711754 |
- |
LOC100288637 |
NNNCCTCTGAAGATGCTCCA |
NGG |
1 |
0.65 |
Tier III |
20 |
NC_000001.11 |
1 |
193834233 |
+ |
LOC124904475 |
NNNCCTCTGAAGAAACTCCA |
NGG |
1 |
0.619 |
Tier III |
21 |
NC_000005.10 |
5 |
135320918 |
+ |
PITX1-AS1 |
NNNCGTCTGAAGATGCTCCA |
NGG |
2 |
0.39 |
Tier III |
22 |
NC_000017.11 |
17 |
52460822 |
- |
LINC01982 |
NNNCCTTTGAAGATACTGCA |
NGG |
2 |
0.1083 |
Tier III |
23 |
NC_000004.12 |
4 |
96674978 |
+ |
LINC02267 |
NNNCCTCTGAAGATCCTCCA |
NAG |
2 |
0.0707 |
Tier III |
24 |
NC_000015.10 |
15 |
61555202 |
+ |
LOC107984782 |
NNNCCTTTGAAGAGACTCCA |
NGG |
2 |
0.0 |
Tier III |
Gene matches for this target sequence (CRISPRko, PAM=NGG, mouse):
| Reference Sequence |
Chromosome |
Cut Position |
Match Strand |
Match Gene |
Match Sequence |
PAM Seq. |
Mismatches[?]Genomic matches are found by querying with a reduced sequence corresponding to the final 17mer of the 20mer guide target sequence, combined with the `GG` of the PAM sequence. Mismatches are assessed within this set of bases only, for a total of 19 possible matching bases. |
CFD Score[?]Off target matches are assesed via a Cutting Frequency Determination, or CFD score. This value provides an estimate of how specific mismatches affect the likelihood that an sgRNA will cut a given target sequence. For more information, see Doench, Fusi et al., Nature Biotechnology 2016. |
Match Tier[?]For a description of CRISPR match tiers, see How the sgRNA Designer Works. |
1 |
NC_000067.6 |
1 |
87676312 |
- |
Inpp5d |
NNNCCTCTGCAGAGACTCCA |
NGG |
2 |
0.0 |
Tier I |
2 |
NC_000077.6 |
11 |
81428459 |
- |
Asic2 |
NNNCCACAGAAGATACTCCA |
NGG |
2 |
0.6933 |
Tier II |
3 |
NC_000068.7 |
2 |
40813690 |
- |
Lrp1b |
NNNACTTTGAAGATACTCCA |
NGG |
2 |
0.6842 |
Tier II |
4 |
NC_000072.6 |
6 |
136747670 |
- |
Gucy2c |
NNNCCTCAGGAGATACTCCA |
NGG |
2 |
0.4444 |
Tier II |
5 |
NC_000072.6 |
6 |
32147423 |
+ |
Plxna4 |
NNNCCTCTGAACAAACTCCA |
NGG |
2 |
0.3277 |
Tier II |
6 |
NC_000071.6 |
5 |
31691498 |
- |
Rbks |
NNNCGTCTGAAGATACACCA |
NGG |
2 |
0.32 |
Tier II |
7 |
NC_000075.6 |
9 |
58095194 |
- |
Stra6 |
NNNCCTCTGAACATACACCA |
NGG |
2 |
0.2824 |
Tier II |
8 |
NC_000075.6 |
9 |
58095194 |
- |
Ccdc33 |
NNNCCTCTGAACATACACCA |
NGG |
2 |
0.2824 |
Tier II |
9 |
NC_000070.6 |
4 |
151282114 |
- |
Camta1 |
NNNCCTCTGAAGAAACTCAA |
NGG |
2 |
0.2653 |
Tier II |
10 |
NC_000075.6 |
9 |
62783042 |
+ |
Itga11 |
NNNCCTCTGAAGAAACTCAA |
NGG |
2 |
0.2653 |
Tier II |
11 |
NC_000078.6 |
12 |
104748490 |
+ |
Dicer1 |
NNNACTCTGAAGATATTCCA |
NGG |
2 |
0.2591 |
Tier II |
12 |
NC_000077.6 |
11 |
50777306 |
- |
Adamts2 |
NNNCCTCTGCAGATACTACA |
NGG |
2 |
0.1795 |
Tier II |
13 |
NC_000074.6 |
8 |
83185395 |
- |
Tbc1d9 |
NNNCCTCTGTAGATTCTCCA |
NGG |
2 |
0.1765 |
Tier II |
14 |
NC_000080.6 |
14 |
124591401 |
- |
Fgf14 |
NNNCCTCAGAAGATAGTCCA |
NGG |
2 |
0.1231 |
Tier II |
15 |
NC_000073.6 |
7 |
40911903 |
+ |
Vstm2b |
NNNCCTCTGAAGACACTCAA |
NGG |
2 |
0.1224 |
Tier II |
16 |
NC_000072.6 |
6 |
85291045 |
- |
Sfxn5 |
NNNTCTCTGAAGATACTGCA |
NGG |
2 |
0.1067 |
Tier II |
17 |
NC_000077.6 |
11 |
113280960 |
- |
Slc39a11 |
NNNCCTCTGAAGACACGCCA |
NGG |
2 |
0.0336 |
Tier II |
18 |
NC_000082.6 |
16 |
41262517 |
- |
Lsamp |
NNNCCTCTGAAGATAATCCA |
NGC |
2 |
0.0222 |
Tier II |
19 |
NC_000086.7 |
X |
139605295 |
+ |
Rnf128 |
NNNCCTCTGTAGATACTCCA |
NGT |
2 |
0.0142 |
Tier II |
20 |
NC_000071.6 |
5 |
148514529 |
+ |
Ubl3 |
NNNCCTCTGAAGATTCTCCA |
NTG |
2 |
0.0078 |
Tier II |
21 |
NC_000076.6 |
10 |
43978428 |
+ |
Crybg1 |
NNNCCTCTGAAGATACTGCA |
NTG |
2 |
0.0052 |
Tier II |
22 |
NC_000080.6 |
14 |
29285720 |
- |
Cacna2d3 |
NNNCCTCTGAAGAGACTGCA |
NGG |
2 |
0.0 |
Tier II |
23 |
NC_000084.6 |
18 |
62980047 |
- |
Napg |
NNNCCTCTGAGGAGACTCCA |
NGG |
2 |
0.0 |
Tier II |
24 |
NC_000078.6 |
12 |
111231665 |
- |
Traf3 |
NNNGCTCTGAAGAGACTCCA |
NGG |
2 |
0.0 |
Tier II |
25 |
NC_000078.6 |
12 |
11064057 |
- |
7420701I03Rik |
NNNCCTCAGAAGATACTCCA |
NAG |
2 |
0.2074 |
Tier III |
26 |
NC_000077.6 |
11 |
34040452 |
+ |
4930469K13Rik |
NNNCCTCTGATGGTACTCCA |
NGG |
2 |
0.2007 |
Tier III |
27 |
NC_000067.6 |
1 |
51594962 |
+ |
Gm17767 |
NNNGCTCTGAAGATCCTCCA |
NGG |
2 |
0.1364 |
Tier III |
28 |
NC_000081.6 |
15 |
87897519 |
- |
Gm35599 |
NNNCCTCTGCAGATCCTCCA |
NGG |
2 |
0.0909 |
Tier III |
29 |
NC_000076.6 |
10 |
43978428 |
+ |
Gm40636 |
NNNCCTCTGAAGATACTGCA |
NTG |
2 |
0.0052 |
Tier III |
Other clones with same target sequence:
(none)