Construct: sgRNA BRDN0001146864
Construct Description:
- Construct Type:
- sgRNA
- Other Identifiers:
- n/a
- DNA Barcode:
- GTGCCACAAAGACCATCAAG
Original Target:
- Taxon:
-
Homo sapiens (human)
- Gene:
- CD2 (914)
- Gene Description:
- n/a
- CRISPR Mechanism
- CRISPRko
Vector Information:
- Vector Backbone:
- pXPR_003
- Pol II Cassette 1:
- EF1A-PuroR
- Pol II Cassette 2:
- n/a
- Selection Marker:
- PuroR
- Visible Reporter:
- n/a
- Epitope Tag:
- n/a
Additional Information:
- Addgene ID:
- 75827
Gene matches for this target sequence (CRISPRko, PAM=NGG, human):
| Reference Sequence |
Chromosome |
Cut Position |
Match Strand |
Match Gene |
Match Sequence |
PAM Seq. |
Mismatches[?]Genomic matches are found by querying with a reduced sequence corresponding to the final 17mer of the 20mer guide target sequence, combined with the `GG` of the PAM sequence. Mismatches are assessed within this set of bases only, for a total of 19 possible matching bases. |
CFD Score[?]Off target matches are assesed via a Cutting Frequency Determination, or CFD score. This value provides an estimate of how specific mismatches affect the likelihood that an sgRNA will cut a given target sequence. For more information, see Doench, Fusi et al., Nature Biotechnology 2016. |
Match Tier[?]For a description of CRISPR match tiers, see How the sgRNA Designer Works. |
1 |
NC_000001.11 |
1 |
116764539 |
- |
CD2 |
NNNCCACAAAGACCATCAAG |
NGG |
0 |
1.0 |
Tier I |
2 |
NC_000001.11 |
1 |
36137884 |
+ |
TRAPPC3 |
NNNCCACAAAGTCCACCAAG |
NGG |
2 |
0.2222 |
Tier I |
3 |
NC_000010.11 |
10 |
101404654 |
- |
BTRC |
NNNCCACAATGGCCATCAAG |
NGG |
2 |
0.6373 |
Tier II |
4 |
NC_000017.11 |
17 |
19907741 |
- |
AKAP10 |
NNNAGACAAAGACCATCAAG |
NGG |
2 |
0.5053 |
Tier II |
5 |
NC_000011.10 |
11 |
131625295 |
- |
NTM |
NNNCCATAAAGACCATCATG |
NGG |
2 |
0.4375 |
Tier II |
6 |
NC_000020.11 |
20 |
8631688 |
- |
PLCB1 |
NNNCCACAATGACCATTAAG |
NGG |
2 |
0.4118 |
Tier II |
7 |
NC_000001.11 |
1 |
210791272 |
+ |
KCNH1 |
NNNCCACAAAAAACATCAAG |
NGG |
2 |
0.3846 |
Tier II |
8 |
NC_000001.11 |
1 |
162157927 |
- |
NOS1AP |
NNNTCAGAAAGACCATCAAG |
NGG |
2 |
0.3765 |
Tier II |
9 |
NC_000013.11 |
13 |
31228043 |
- |
B3GLCT |
NNNCCACAAAGACCATCAGA |
NGG |
2 |
0.3516 |
Tier II |
10 |
NC_000020.11 |
20 |
41141148 |
- |
PLCG1 |
NNNCCACAAAGACCCTCAAA |
NGG |
2 |
0.2557 |
Tier II |
11 |
NC_000007.14 |
7 |
117210306 |
- |
ST7 |
NNNCCACAAAGGCCATCAAG |
NAG |
2 |
0.1872 |
Tier II |
12 |
NC_000017.11 |
17 |
9363162 |
+ |
STX8 |
NNNCCTCAAAGACCATCCAG |
NGG |
2 |
0.1361 |
Tier II |
13 |
NC_000021.9 |
21 |
31249505 |
+ |
TIAM1 |
NNNCCAGAAAGACCCTCAAG |
NGG |
2 |
0.1283 |
Tier II |
14 |
NC_000003.12 |
3 |
123307885 |
+ |
ADCY5 |
NNNCCACAAGGACCATCCAG |
NGG |
2 |
0.1058 |
Tier II |
15 |
NC_000011.10 |
11 |
95120150 |
- |
ENDOD1 |
NNNCCACAGAGAGCATCAAG |
NGG |
2 |
0.0909 |
Tier II |
16 |
NC_000019.10 |
19 |
7147893 |
+ |
INSR |
NNNCCAAAAAGACCATGAAG |
NGG |
2 |
0.0441 |
Tier II |
17 |
NC_000009.12 |
9 |
71091259 |
- |
TRPM3 |
NNNCCACAAAGACCATAAAG |
NGA |
2 |
0.0324 |
Tier II |
18 |
NC_000008.11 |
8 |
21984182 |
+ |
XPO7 |
NNNCCACAAAGCCCATCAAG |
NGT |
2 |
0.0042 |
Tier II |
19 |
NC_000004.12 |
4 |
10536126 |
+ |
CLNK |
NNNCCACAAAGACCATCCAG |
NGT |
2 |
0.0031 |
Tier II |
20 |
NC_000020.11 |
20 |
8631688 |
- |
LOC105372521 |
NNNCCACAATGACCATTAAG |
NGG |
2 |
0.4118 |
Tier III |
21 |
NC_000001.11 |
1 |
162157927 |
- |
LOC105371475 |
NNNTCAGAAAGACCATCAAG |
NGG |
2 |
0.3765 |
Tier III |
22 |
NC_000008.11 |
8 |
127330496 |
+ |
CASC8 |
NNNCCACAAAGAACATCAAA |
NGG |
2 |
0.3606 |
Tier III |
23 |
NC_000008.11 |
8 |
127330496 |
+ |
CASC21 |
NNNCCACAAAGAACATCAAA |
NGG |
2 |
0.3606 |
Tier III |
24 |
NC_000012.12 |
12 |
67351910 |
+ |
MRPL40P1 |
NNNCCACTGAGACCATCAAG |
NGG |
2 |
0.2857 |
Tier III |
25 |
NC_000012.12 |
12 |
67351910 |
+ |
LOC124902957 |
NNNCCACTGAGACCATCAAG |
NGG |
2 |
0.2857 |
Tier III |
26 |
NC_000008.11 |
8 |
88852505 |
- |
LOC105375630 |
NNNTCACAAAGACAATCAAG |
NGG |
2 |
0.28 |
Tier III |
27 |
NC_000005.10 |
5 |
89771894 |
+ |
LINC02161 |
NNNCCTCAAAGACAATCAAG |
NGG |
2 |
0.25 |
Tier III |
Gene matches for this target sequence (CRISPRko, PAM=NGG, mouse):
| Reference Sequence |
Chromosome |
Cut Position |
Match Strand |
Match Gene |
Match Sequence |
PAM Seq. |
Mismatches[?]Genomic matches are found by querying with a reduced sequence corresponding to the final 17mer of the 20mer guide target sequence, combined with the `GG` of the PAM sequence. Mismatches are assessed within this set of bases only, for a total of 19 possible matching bases. |
CFD Score[?]Off target matches are assesed via a Cutting Frequency Determination, or CFD score. This value provides an estimate of how specific mismatches affect the likelihood that an sgRNA will cut a given target sequence. For more information, see Doench, Fusi et al., Nature Biotechnology 2016. |
Match Tier[?]For a description of CRISPR match tiers, see How the sgRNA Designer Works. |
1 |
NC_000077.6 |
11 |
114984268 |
+ |
Cd300ld |
NNNCCACAAAGACCATCAGC |
NGG |
2 |
0.1607 |
Tier I |
2 |
NC_000084.6 |
18 |
77010973 |
- |
Katnal2 |
NNNCCACAAAGACCAGCCAG |
NGG |
2 |
0.0659 |
Tier I |
3 |
NC_000086.7 |
X |
73893231 |
- |
Avpr2 |
NNNCCACAAACACCATCAAG |
NCG |
2 |
0.0459 |
Tier I |
4 |
NC_000071.6 |
5 |
74212336 |
+ |
Scfd2 |
NNNCCACAAAGAGGATCAAG |
NGG |
2 |
0.0 |
Tier I |
5 |
NC_000079.6 |
13 |
40190649 |
- |
Ofcc1 |
NNNTCACAATGACCATCAAG |
NGG |
2 |
0.7059 |
Tier II |
6 |
NC_000084.6 |
18 |
33952746 |
+ |
Epb41l4a |
NNNTCACAGAGACCATCAAG |
NGG |
2 |
0.5333 |
Tier II |
7 |
NC_000076.6 |
10 |
109724854 |
+ |
Nav3 |
NNNCCTCAAAGACCATCAAT |
NGG |
2 |
0.5 |
Tier II |
8 |
NC_000080.6 |
14 |
123742597 |
- |
Itgbl1 |
NNNCCACAGAGGCCATCAAG |
NGG |
2 |
0.4815 |
Tier II |
9 |
NC_000080.6 |
14 |
123850759 |
- |
Itgbl1 |
NNNACACAAAGACCATCAAC |
NGG |
2 |
0.3609 |
Tier II |
10 |
NC_000075.6 |
9 |
46091722 |
- |
Sik3 |
NNNCCACAAAGACCATCAGA |
NGG |
2 |
0.3516 |
Tier II |
11 |
NC_000068.7 |
2 |
129506313 |
- |
F830045P16Rik |
NNNCCAGGAAGACCATCAAG |
NGG |
2 |
0.3451 |
Tier II |
12 |
NC_000073.6 |
7 |
12846698 |
+ |
Zfp110 |
NNNCAACATAGACCATCAAG |
NGG |
2 |
0.3429 |
Tier II |
13 |
NC_000075.6 |
9 |
76516973 |
- |
Fam83b |
NNNTCACAAAGACCATCAAC |
NGG |
2 |
0.3429 |
Tier II |
14 |
NC_000079.6 |
13 |
49440821 |
+ |
Ippk |
NNNCCACAAAGGCCATAAAG |
NGG |
2 |
0.337 |
Tier II |
15 |
NC_000071.6 |
5 |
124021008 |
+ |
Vps37b |
NNNCCACAGAGACCATAAAG |
NGG |
2 |
0.3111 |
Tier II |
16 |
NC_000070.6 |
4 |
123404096 |
+ |
Macf1 |
NNNCCACAAAGGCCATCAAC |
NGG |
2 |
0.3095 |
Tier II |
17 |
NC_000070.6 |
4 |
123404096 |
+ |
D830031N03Rik |
NNNCCACAAAGGCCATCAAC |
NGG |
2 |
0.3095 |
Tier II |
18 |
NC_000069.6 |
3 |
31218850 |
+ |
Slc7a14 |
NNNACACAAAGACCAGCAAG |
NGG |
2 |
0.2915 |
Tier II |
19 |
NC_000071.6 |
5 |
90302261 |
- |
Ankrd17 |
NNNCCATAAAGACAATCAAG |
NGG |
2 |
0.2844 |
Tier II |
20 |
NC_000068.7 |
2 |
25266732 |
- |
Tprn |
NNNCCAGAAAGACCATCTAG |
NGG |
2 |
0.2353 |
Tier II |
21 |
NC_000075.6 |
9 |
45565328 |
+ |
Dscaml1 |
NNNCCACACAGACCAGCAAG |
NGG |
2 |
0.1978 |
Tier II |
22 |
NC_000073.6 |
7 |
55979958 |
+ |
Nipa1 |
NNNCCCCAAACACCATCAAG |
NGG |
2 |
0.1948 |
Tier II |
23 |
NC_000074.6 |
8 |
111085031 |
- |
Clec18a |
NNNCCAAAAAGACCATCAAG |
NAG |
2 |
0.1944 |
Tier II |
24 |
NC_000070.6 |
4 |
110404036 |
- |
Agbl4 |
NNNCCACAAAGACCATCCAG |
NGG |
1 |
0.1905 |
Tier II |
25 |
NC_000074.6 |
8 |
118486972 |
+ |
Cdh13 |
NNNCCACTAACACCATCAAG |
NGG |
2 |
0.1837 |
Tier II |
26 |
NC_000079.6 |
13 |
109346560 |
- |
Pde4d |
NNNCCACAAAGACCAGAAAG |
NGG |
2 |
0.1615 |
Tier II |
27 |
NC_000080.6 |
14 |
22419755 |
- |
Lrmda |
NNNCCACAACCACCATCAAG |
NGG |
2 |
0.1429 |
Tier II |
28 |
NC_000070.6 |
4 |
98692691 |
+ |
Patj |
NNNGCACAAAGCCCATCAAG |
NGG |
2 |
0.1316 |
Tier II |
29 |
NC_000080.6 |
14 |
27724286 |
+ |
Erc2 |
NNNCCACAAAGACCATCTAG |
NAG |
2 |
0.1296 |
Tier II |
30 |
NC_000076.6 |
10 |
127461357 |
+ |
R3hdm2 |
NNNTCACAAAGAGCATCAAG |
NGG |
2 |
0.1091 |
Tier II |
31 |
NC_000073.6 |
7 |
67146961 |
- |
Adamts17 |
NNNACACAAAGACCATCAAG |
NGA |
2 |
0.0585 |
Tier II |
32 |
NC_000067.6 |
1 |
159253967 |
- |
Cop1 |
NNNCCACAAAGACCACCAAG |
NGA |
2 |
0.0463 |
Tier II |
33 |
NC_000083.6 |
17 |
49686596 |
+ |
Kif6 |
NNNCCACAAAGACCATCATG |
NTG |
2 |
0.021 |
Tier II |
34 |
NC_000067.6 |
1 |
104958534 |
+ |
Cdh20 |
NNNCCACAAAGAACATCAAG |
NGT |
2 |
0.0062 |
Tier II |
35 |
NC_000068.7 |
2 |
130396021 |
+ |
Cpxm1 |
NNNCCACAAAGACGAGCAAG |
NGG |
2 |
0.0 |
Tier II |
36 |
NC_000068.7 |
2 |
129506313 |
- |
Gm14040 |
NNNCCAGGAAGACCATCAAG |
NGG |
2 |
0.3451 |
Tier III |
37 |
NC_000080.6 |
14 |
71680749 |
+ |
Gm34819 |
NNNCCTCCAAGACCATCAAG |
NGG |
2 |
0.3061 |
Tier III |
38 |
NC_000067.6 |
1 |
173714114 |
+ |
Gm7871 |
NNNCCACAAAGGACATCAAG |
NGG |
2 |
0.2778 |
Tier III |
39 |
NC_000073.6 |
7 |
55979958 |
+ |
A230056P14Rik |
NNNCCCCAAACACCATCAAG |
NGG |
2 |
0.1948 |
Tier III |
Other clones with same target sequence:
(none)