Construct: sgRNA BRDN0001146878
Construct Description:
- Construct Type:
- sgRNA
- Other Identifiers:
- n/a
- DNA Barcode:
- AGAATATAGAGAATGACACC
Original Target:
- Taxon:
-
Homo sapiens (human)
- Gene:
- CAMK2D (817)
- Gene Description:
- n/a
- CRISPR Mechanism
- CRISPRko
Vector Information:
- Vector Backbone:
- pXPR_003
- Pol II Cassette 1:
- EF1A-PuroR
- Pol II Cassette 2:
- n/a
- Selection Marker:
- PuroR
- Visible Reporter:
- n/a
- Epitope Tag:
- n/a
Additional Information:
- Addgene ID:
- 77186
Gene matches for this target sequence (CRISPRko, PAM=NGG, human):
Gene matches for this target sequence (CRISPRko, PAM=NGG, mouse):
| Reference Sequence |
Chromosome |
Cut Position |
Match Strand |
Match Gene |
Match Sequence |
PAM Seq. |
Mismatches[?]Genomic matches are found by querying with a reduced sequence corresponding to the final 17mer of the 20mer guide target sequence, combined with the `GG` of the PAM sequence. Mismatches are assessed within this set of bases only, for a total of 19 possible matching bases. |
CFD Score[?]Off target matches are assesed via a Cutting Frequency Determination, or CFD score. This value provides an estimate of how specific mismatches affect the likelihood that an sgRNA will cut a given target sequence. For more information, see Doench, Fusi et al., Nature Biotechnology 2016. |
Match Tier[?]For a description of CRISPR match tiers, see How the sgRNA Designer Works. |
1 |
NC_000084.6 |
18 |
20107697 |
- |
Dsc1 |
NNNACATAGAGAAAGACACC |
NGG |
2 |
0.619 |
Tier I |
2 |
NC_000067.6 |
1 |
128134521 |
+ |
R3hdm1 |
NNNACTTAGAGAATGACACC |
NGG |
2 |
0.7143 |
Tier II |
3 |
NC_000086.7 |
X |
100367025 |
- |
Eda |
NNNATGTAGAGAATAACACC |
NGG |
2 |
0.6723 |
Tier II |
4 |
NC_000082.6 |
16 |
12011514 |
+ |
Shisa9 |
NNNATATAGAGAATGACTCC |
NGG |
1 |
0.5 |
Tier II |
5 |
NC_000079.6 |
13 |
38215066 |
- |
Snrnp48 |
NNNATGCAGAGAATGACACC |
NGG |
2 |
0.4911 |
Tier II |
6 |
NC_000072.6 |
6 |
145156822 |
- |
Lrmp |
NNNATAAAGGGAATGACACC |
NGG |
2 |
0.4861 |
Tier II |
7 |
NC_000074.6 |
8 |
20900597 |
+ |
Gm15056 |
NNNATAAAGAGAATGACACA |
NGG |
2 |
0.4375 |
Tier II |
8 |
NC_000071.6 |
5 |
103973414 |
- |
Hsd17b13 |
NNNGGATAGAGAATGACACC |
NGG |
2 |
0.4 |
Tier II |
9 |
NC_000081.6 |
15 |
32401195 |
- |
Sema5a |
NNNATACAGAGAATGACAAC |
NGG |
2 |
0.2946 |
Tier II |
10 |
NC_000081.6 |
15 |
73518158 |
+ |
Dennd3 |
NNNAAAGAGAGAATGACACC |
NGG |
2 |
0.2941 |
Tier II |
11 |
NC_000071.6 |
5 |
141664594 |
- |
Sdk1 |
NNNATATAGACAATGACACA |
NGG |
2 |
0.2143 |
Tier II |
12 |
NC_000073.6 |
7 |
26671536 |
+ |
Cyp2b23 |
NNNATACAGAGAATCACACC |
NGG |
2 |
0.1875 |
Tier II |
13 |
NC_000071.6 |
5 |
87003853 |
+ |
Ugt2b35 |
NNNATGTAGAGAATGACACC |
NAG |
2 |
0.1852 |
Tier II |
14 |
NC_000081.6 |
15 |
98220285 |
+ |
Olfr287 |
NNNATATAGAGAAACACACC |
NGG |
2 |
0.1688 |
Tier II |
15 |
NC_000073.6 |
7 |
65660380 |
- |
Tarsl2 |
NNNATTTAGAGACTGACACC |
NGG |
2 |
0.1504 |
Tier II |
16 |
NC_000070.6 |
4 |
156042924 |
+ |
Ttll10 |
NNNATATAGAAAATTACACC |
NGG |
2 |
0.1429 |
Tier II |
17 |
NC_000068.7 |
2 |
161011825 |
- |
Chd6 |
NNNATATATAGCATGACACC |
NGG |
2 |
0.1404 |
Tier II |
18 |
NC_000085.6 |
19 |
53961376 |
- |
Shoc2 |
NNNATATAGAGAATCACAAC |
NGG |
2 |
0.1169 |
Tier II |
19 |
NC_000075.6 |
9 |
34831188 |
+ |
Kirrel3 |
NNNATATACAGAATGGCACC |
NGG |
2 |
0.1036 |
Tier II |
20 |
NC_000070.6 |
4 |
43351540 |
- |
Atp8b5 |
NNNATATAGAGACTGACAAC |
NGG |
2 |
0.0902 |
Tier II |
21 |
NC_000075.6 |
9 |
117602399 |
- |
Rbms3 |
NNNATATAGAGAAAGACACC |
NGA |
2 |
0.043 |
Tier II |
22 |
NC_000078.6 |
12 |
79458222 |
- |
Rad51b |
NNNATATAGAGAAAGACACC |
NGA |
2 |
0.043 |
Tier II |
23 |
NC_000083.6 |
17 |
25167236 |
+ |
Ccdc154 |
NNNATAGAGAGAATGAGACC |
NGG |
2 |
0.0346 |
Tier II |
24 |
NC_000077.6 |
11 |
116811487 |
+ |
Mxra7 |
NNNAGATAGAGAATGACACC |
NTG |
2 |
0.0249 |
Tier II |
25 |
NC_000080.6 |
14 |
103056003 |
- |
Acod1 |
NNNATATAGAGAATGAAACC |
NTG |
2 |
0.0182 |
Tier II |
26 |
NC_000069.6 |
3 |
67024352 |
- |
Rsrc1 |
NNNATATAGAGAATTACACC |
NGA |
2 |
0.0099 |
Tier II |
27 |
NC_000067.6 |
1 |
128134521 |
+ |
Gm29383 |
NNNACTTAGAGAATGACACC |
NGG |
2 |
0.7143 |
Tier III |
28 |
NC_000076.6 |
10 |
125913279 |
+ |
Gm29944 |
NNNAGATAGAAAATGACACC |
NGG |
2 |
0.64 |
Tier III |
29 |
NC_000069.6 |
3 |
27811135 |
- |
Gm32795 |
NNNATATAGTTAATGACACC |
NGG |
2 |
0.3394 |
Tier III |
30 |
NC_000069.6 |
3 |
27811135 |
- |
Gm42194 |
NNNATATAGTTAATGACACC |
NGG |
2 |
0.3394 |
Tier III |
31 |
NC_000068.7 |
2 |
138659023 |
- |
Gm14061 |
NNNATCTAGAGAAAGACACC |
NGG |
2 |
0.2814 |
Tier III |
32 |
NC_000073.6 |
7 |
136114759 |
- |
Gm51502 |
NNNATATAGAGAGTGACACC |
NAG |
2 |
0.1691 |
Tier III |
33 |
NC_000075.6 |
9 |
34831188 |
+ |
Gm33561 |
NNNATATACAGAATGGCACC |
NGG |
2 |
0.1036 |
Tier III |
Other clones with same target sequence:
(none)