Construct: sgRNA BRDN0001147061
Construct Description:
- Construct Type:
- sgRNA
- Other Identifiers:
- n/a
- DNA Barcode:
- TGCAGAGCGTGGGAAAACAC
Original Target:
- Taxon:
-
Homo sapiens (human)
- Gene:
- PRKCD (5580)
- Gene Description:
- n/a
- CRISPR Mechanism
- CRISPRko
Vector Information:
- Vector Backbone:
- pXPR_003
- Pol II Cassette 1:
- EF1A-PuroR
- Pol II Cassette 2:
- n/a
- Selection Marker:
- PuroR
- Visible Reporter:
- n/a
- Epitope Tag:
- n/a
Additional Information:
- Addgene ID:
- 76004
Gene matches for this target sequence (CRISPRko, PAM=NGG, human):
Gene matches for this target sequence (CRISPRko, PAM=NGG, mouse):
| Reference Sequence |
Chromosome |
Cut Position |
Match Strand |
Match Gene |
Match Sequence |
PAM Seq. |
Mismatches[?]Genomic matches are found by querying with a reduced sequence corresponding to the final 17mer of the 20mer guide target sequence, combined with the `GG` of the PAM sequence. Mismatches are assessed within this set of bases only, for a total of 19 possible matching bases. |
CFD Score[?]Off target matches are assesed via a Cutting Frequency Determination, or CFD score. This value provides an estimate of how specific mismatches affect the likelihood that an sgRNA will cut a given target sequence. For more information, see Doench, Fusi et al., Nature Biotechnology 2016. |
Match Tier[?]For a description of CRISPR match tiers, see How the sgRNA Designer Works. |
1 |
NC_000080.6 |
14 |
30609290 |
- |
Prkcd |
NNNAGAGCGAGGGAAGACAC |
NGG |
2 |
0.1648 |
Tier I |
2 |
NC_000070.6 |
4 |
20449633 |
- |
Nkain3 |
NNNAGACCGTGGGAAAACAC |
NGG |
1 |
0.6875 |
Tier II |
3 |
NC_000071.6 |
5 |
124215877 |
+ |
Pitpnm2 |
NNNAGAGCCTGAGAAAACAC |
NGG |
2 |
0.5026 |
Tier II |
4 |
NC_000068.7 |
2 |
130633846 |
+ |
Lzts3 |
NNNAGATCGAGGGAAAACAC |
NGG |
2 |
0.4898 |
Tier II |
5 |
NC_000077.6 |
11 |
105984740 |
+ |
Ace |
NNNAGCACGTGGGAAAACAC |
NGG |
2 |
0.4545 |
Tier II |
6 |
NC_000082.6 |
16 |
13577120 |
+ |
Parn |
NNNAGACCATGGGAAAACAC |
NGG |
2 |
0.442 |
Tier II |
7 |
NC_000067.6 |
1 |
88096948 |
- |
Ugt1a10 |
NNNTGAGAGTGGGAAAACAC |
NGG |
2 |
0.4136 |
Tier II |
8 |
NC_000067.6 |
1 |
88096948 |
- |
Ugt1a7c |
NNNTGAGAGTGGGAAAACAC |
NGG |
2 |
0.4136 |
Tier II |
9 |
NC_000067.6 |
1 |
88096948 |
- |
Ugt1a9 |
NNNTGAGAGTGGGAAAACAC |
NGG |
2 |
0.4136 |
Tier II |
10 |
NC_000067.6 |
1 |
88096948 |
- |
Ugt1a8 |
NNNTGAGAGTGGGAAAACAC |
NGG |
2 |
0.4136 |
Tier II |
11 |
NC_000067.6 |
1 |
88128392 |
- |
Ugt1a10 |
NNNTGAGAGTGGGAAAACAC |
NGG |
2 |
0.4136 |
Tier II |
12 |
NC_000067.6 |
1 |
88128392 |
- |
Ugt1a7c |
NNNTGAGAGTGGGAAAACAC |
NGG |
2 |
0.4136 |
Tier II |
13 |
NC_000067.6 |
1 |
88128392 |
- |
Ugt1a9 |
NNNTGAGAGTGGGAAAACAC |
NGG |
2 |
0.4136 |
Tier II |
14 |
NC_000067.6 |
1 |
88128392 |
- |
Ugt1a6b |
NNNTGAGAGTGGGAAAACAC |
NGG |
2 |
0.4136 |
Tier II |
15 |
NC_000067.6 |
1 |
88128392 |
- |
Ugt1a8 |
NNNTGAGAGTGGGAAAACAC |
NGG |
2 |
0.4136 |
Tier II |
16 |
NC_000067.6 |
1 |
21456452 |
+ |
Kcnq5 |
NNNAGGGCCTGGGAAAACAC |
NGG |
2 |
0.3846 |
Tier II |
17 |
NC_000076.6 |
10 |
75108534 |
- |
Bcr |
NNNAGAGGGTGGGAAAACAA |
NGG |
2 |
0.3214 |
Tier II |
18 |
NC_000074.6 |
8 |
47339413 |
+ |
Stox2 |
NNNAGAGCATCGGAAAACAC |
NGG |
2 |
0.2755 |
Tier II |
19 |
NC_000080.6 |
14 |
67865402 |
- |
Dock5 |
NNNAGAGCTGGGGAAAACAC |
NGG |
2 |
0.2667 |
Tier II |
20 |
NC_000070.6 |
4 |
24567437 |
- |
Mms22l |
NNNAGAGCATTGGAAAACAC |
NGG |
2 |
0.2473 |
Tier II |
21 |
NC_000084.6 |
18 |
61161491 |
+ |
Hmgxb3 |
NNNAAAGCGTGGGAAAACAC |
NAG |
2 |
0.2247 |
Tier II |
22 |
NC_000076.6 |
10 |
71064433 |
+ |
Bicc1 |
NNNAGAGCCTTGGAAAACAC |
NGG |
2 |
0.2071 |
Tier II |
23 |
NC_000073.6 |
7 |
43799884 |
- |
Klk8 |
NNNAGAGCGTGGGAAAAAGC |
NGG |
2 |
0.2019 |
Tier II |
24 |
NC_000069.6 |
3 |
86857673 |
+ |
Dclk2 |
NNNAGAGAGTGGGAAAACCC |
NGG |
2 |
0.1345 |
Tier II |
25 |
NC_000074.6 |
8 |
124743868 |
- |
Fam89a |
NNNAGAGGGTGGGAAACCAC |
NGG |
2 |
0.1134 |
Tier II |
26 |
NC_000076.6 |
10 |
7658848 |
- |
Pcmt1 |
NNNAGGGCGTGGGAAAAGAC |
NGG |
2 |
0.0952 |
Tier II |
27 |
NC_000068.7 |
2 |
27418790 |
+ |
Vav2 |
NNNAGAGCCTGGGAAAGCAC |
NGG |
2 |
0.095 |
Tier II |
28 |
NC_000079.6 |
13 |
103052433 |
- |
Mast4 |
NNNAGAGAGTGGGAAATCAC |
NGG |
2 |
0.0867 |
Tier II |
29 |
NC_000082.6 |
16 |
36455189 |
- |
Stfa3 |
NNNAGAGTGTGGGAAAACAC |
NGA |
2 |
0.0608 |
Tier II |
30 |
NC_000068.7 |
2 |
121565324 |
- |
Frmd5 |
NNNAGACCGTGGGAAAACAC |
NGA |
2 |
0.0477 |
Tier II |
31 |
NC_000071.6 |
5 |
125141960 |
- |
Ncor2 |
NNNAGACCGTGGGAAAACAC |
NGA |
2 |
0.0477 |
Tier II |
32 |
NC_000073.6 |
7 |
58714715 |
- |
Atp10a |
NNNAGAGTGTGGGAAAACAC |
NGT |
2 |
0.0141 |
Tier II |
33 |
NC_000068.7 |
2 |
141053844 |
+ |
Macrod2 |
NNNAGACCGTGGGAATACAC |
NGG |
2 |
0.0 |
Tier II |
34 |
NC_000068.7 |
2 |
3195105 |
- |
Fam171a1 |
NNNAGAGAGTGGGAACACAC |
NGG |
2 |
0.0 |
Tier II |
35 |
NC_000080.6 |
14 |
32454431 |
- |
Chat |
NNNAGAGGGTGGGAACACAC |
NGG |
2 |
0.0 |
Tier II |
36 |
NC_000077.6 |
11 |
105984740 |
+ |
Gm11651 |
NNNAGCACGTGGGAAAACAC |
NGG |
2 |
0.4545 |
Tier III |
37 |
NC_000069.6 |
3 |
9179314 |
+ |
Gm33018 |
NNNAGACCATGGGAAAACAC |
NGG |
2 |
0.442 |
Tier III |
38 |
NC_000073.6 |
7 |
58714715 |
- |
Gm39019 |
NNNAGAGTGTGGGAAAACAC |
NGT |
2 |
0.0141 |
Tier III |
Other clones with same target sequence:
(none)