Construct: sgRNA BRDN0001147171
Construct Description:
- Construct Type:
- sgRNA
- Other Identifiers:
- n/a
- DNA Barcode:
- GCCGGATGATCAGATCCCAA
Original Target:
- Taxon:
-
Homo sapiens (human)
- Gene:
- PFKP (5214)
- Gene Description:
- n/a
- CRISPR Mechanism
- CRISPRko
Vector Information:
- Vector Backbone:
- pXPR_003
- Pol II Cassette 1:
- EF1A-PuroR
- Pol II Cassette 2:
- n/a
- Selection Marker:
- PuroR
- Visible Reporter:
- n/a
- Epitope Tag:
- n/a
Additional Information:
- Addgene ID:
- 77628
Gene matches for this target sequence (CRISPRko, PAM=NGG, human):
| Reference Sequence |
Chromosome |
Cut Position |
Match Strand |
Match Gene |
Match Sequence |
PAM Seq. |
Mismatches[?]Genomic matches are found by querying with a reduced sequence corresponding to the final 17mer of the 20mer guide target sequence, combined with the `GG` of the PAM sequence. Mismatches are assessed within this set of bases only, for a total of 19 possible matching bases. |
CFD Score[?]Off target matches are assesed via a Cutting Frequency Determination, or CFD score. This value provides an estimate of how specific mismatches affect the likelihood that an sgRNA will cut a given target sequence. For more information, see Doench, Fusi et al., Nature Biotechnology 2016. |
Match Tier[?]For a description of CRISPR match tiers, see How the sgRNA Designer Works. |
1 |
NC_000010.11 |
10 |
3113184 |
+ |
PFKP |
NNNGGATGATCAGATCCCAA |
NGG |
0 |
1.0 |
Tier I |
2 |
NC_000023.11 |
X |
65030785 |
- |
ZC4H2 |
NNNGAATGATCAGATACCAA |
NGG |
2 |
0.8667 |
Tier II |
3 |
NC_000002.12 |
2 |
53877640 |
+ |
PSME4 |
NNNGGGTGATCAGATACCAA |
NGG |
2 |
0.7143 |
Tier II |
4 |
NC_000005.10 |
5 |
14820646 |
+ |
ANKH |
NNNGGGTGATCAGATACCAA |
NGG |
2 |
0.7143 |
Tier II |
5 |
NC_000019.10 |
19 |
3467469 |
+ |
NFIC |
NNNGGACAATCAGATCCCAA |
NGG |
2 |
0.6875 |
Tier II |
6 |
NC_000002.12 |
2 |
153817398 |
- |
GALNT13 |
NNNGGATGATCAGATATCAA |
NGG |
2 |
0.4667 |
Tier II |
7 |
NC_000011.10 |
11 |
41038325 |
+ |
LRRC4C |
NNNGGGGGATCAGATCCCAA |
NGG |
2 |
0.4202 |
Tier II |
8 |
NC_000004.12 |
4 |
15530787 |
- |
CC2D2A |
NNNGGCTGATCAGATCCCAG |
NGG |
2 |
0.3476 |
Tier II |
9 |
NC_000007.14 |
7 |
150324989 |
- |
LRRC61 |
NNNGGATGAGCAGATCTCAA |
NGG |
2 |
0.2333 |
Tier II |
10 |
NC_000009.12 |
9 |
68424489 |
- |
PGM5 |
NNNGGGTGATTAGATCCCAA |
NGG |
2 |
0.2198 |
Tier II |
11 |
NC_000002.12 |
2 |
85170105 |
+ |
TCF7L1 |
NNNGGAGGATGAGATCCCAA |
NGG |
2 |
0.1471 |
Tier II |
12 |
NC_000001.11 |
1 |
21521067 |
- |
ALPL |
NNNGGATGATCAGATTACAA |
NGG |
2 |
0.1436 |
Tier II |
13 |
NC_000005.10 |
5 |
133821916 |
+ |
FSTL4 |
NNNGGAGGATCAGATGCCAA |
NGG |
2 |
0.0905 |
Tier II |
14 |
NC_000005.10 |
5 |
107474190 |
+ |
EFNA5 |
NNNGGATGATCAGATGCCAC |
NGG |
2 |
0.035 |
Tier II |
15 |
NC_000011.10 |
11 |
8721194 |
+ |
DENND2B |
NNNGGATTATCAGAGCCCAA |
NGG |
2 |
0.0313 |
Tier II |
16 |
NC_000011.10 |
11 |
36435621 |
+ |
PRR5L |
NNNGGATGATTAGAGCCCAA |
NGG |
2 |
0.0154 |
Tier II |
17 |
NC_000009.12 |
9 |
13917196 |
+ |
LOC101929507 |
NNNGAAAGATCAGATCCCAA |
NGG |
2 |
0.7583 |
Tier III |
18 |
NC_000014.9 |
14 |
44783609 |
+ |
LINC02302 |
NNNGGATGATCAGATATCAA |
NGG |
2 |
0.4667 |
Tier III |
19 |
NC_000014.9 |
14 |
97776400 |
- |
LOC105370651 |
NNNGGATGATCAGATATCAA |
NGG |
2 |
0.4667 |
Tier III |
20 |
NC_000003.12 |
3 |
104842048 |
+ |
LOC107986108 |
NNNGGATGATCAGATGCCAA |
NGG |
1 |
0.1538 |
Tier III |
21 |
NC_000012.12 |
12 |
15282662 |
- |
LOC105369673 |
NNNGGATGCTCAGATCCCAA |
NCG |
2 |
0.0612 |
Tier III |
Gene matches for this target sequence (CRISPRko, PAM=NGG, mouse):
| Reference Sequence |
Chromosome |
Cut Position |
Match Strand |
Match Gene |
Match Sequence |
PAM Seq. |
Mismatches[?]Genomic matches are found by querying with a reduced sequence corresponding to the final 17mer of the 20mer guide target sequence, combined with the `GG` of the PAM sequence. Mismatches are assessed within this set of bases only, for a total of 19 possible matching bases. |
CFD Score[?]Off target matches are assesed via a Cutting Frequency Determination, or CFD score. This value provides an estimate of how specific mismatches affect the likelihood that an sgRNA will cut a given target sequence. For more information, see Doench, Fusi et al., Nature Biotechnology 2016. |
Match Tier[?]For a description of CRISPR match tiers, see How the sgRNA Designer Works. |
1 |
NC_000071.6 |
5 |
65380030 |
+ |
Klb |
NNNGGATGATCAGATCCGAA |
NGT |
2 |
0.0022 |
Tier I |
2 |
NC_000071.6 |
5 |
92656901 |
+ |
Ccdc158 |
NNNGGGTGAGCAGATCCCAA |
NGG |
2 |
0.3571 |
Tier II |
3 |
NC_000068.7 |
2 |
106402818 |
+ |
Dcdc5 |
NNNGGATGTTCAGATCACAA |
NGG |
2 |
0.28 |
Tier II |
4 |
NC_000081.6 |
15 |
65877041 |
+ |
Oc90 |
NNNGGATGGTTAGATCCCAA |
NGG |
2 |
0.2051 |
Tier II |
5 |
NC_000072.6 |
6 |
116633637 |
- |
Rassf4 |
NNNGGATCATCAGACCCCAA |
NGG |
2 |
0.1678 |
Tier II |
6 |
NC_000069.6 |
3 |
103638156 |
- |
Syt6 |
NNNGGATGCTCAGATCCCAA |
NAG |
2 |
0.1481 |
Tier II |
7 |
NC_000079.6 |
13 |
30808209 |
- |
Exoc2 |
NNNGGCTGATCAGATTCCAA |
NGG |
2 |
0.1399 |
Tier II |
8 |
NC_000077.6 |
11 |
70542501 |
+ |
Pld2 |
NNNGGATCATCAGATCCCCA |
NGG |
2 |
0.1273 |
Tier II |
9 |
NC_000069.6 |
3 |
76263928 |
+ |
Fstl5 |
NNNGGATGATCACATGCCAA |
NGG |
2 |
0.0648 |
Tier II |
10 |
NC_000076.6 |
10 |
90034925 |
+ |
Anks1b |
NNNGGATGATCAGATTCCAA |
NGC |
2 |
0.0068 |
Tier II |
11 |
NC_000070.6 |
4 |
47635681 |
- |
Gm32544 |
NNNGGATGAGCAGATACCAA |
NGG |
2 |
0.5 |
Tier III |
12 |
NC_000082.6 |
16 |
12809591 |
- |
4930414F18Rik |
NNNGCATCATCAGATCCCAA |
NGG |
2 |
0.4835 |
Tier III |
13 |
NC_000072.6 |
6 |
52248894 |
+ |
Hoxa11os |
NNNGGATGCTCAGATCCCTA |
NGG |
2 |
0.3077 |
Tier III |
14 |
NC_000068.7 |
2 |
106402818 |
+ |
Gm46755 |
NNNGGATGTTCAGATCACAA |
NGG |
2 |
0.28 |
Tier III |
15 |
NC_000077.6 |
11 |
54822020 |
+ |
Lyrm7os |
NNNGGATGAGCAGAGCCCAA |
NGG |
2 |
0.025 |
Tier III |
16 |
NC_000068.7 |
2 |
52384372 |
+ |
Gm13522 |
NNNGGAAGATCAGATCCCAA |
NGC |
2 |
0.0194 |
Tier III |
17 |
NC_000078.6 |
12 |
8148267 |
- |
Gm33037 |
NNNGGATGATCAGAGCCCAA |
NAG |
2 |
0.013 |
Tier III |
Other clones with same target sequence:
(none)