Construct: sgRNA BRDN0001147742
Construct Description:
- Construct Type:
- sgRNA
- Other Identifiers:
- n/a
- DNA Barcode:
- TATACCGAAGAAGTCAGACA
Original Target:
- Taxon:
-
Homo sapiens (human)
- Gene:
- NTPCR (84284)
- Gene Description:
- n/a
- CRISPR Mechanism
- CRISPRko
Vector Information:
- Vector Backbone:
- pXPR_003
- Pol II Cassette 1:
- EF1A-PuroR
- Pol II Cassette 2:
- n/a
- Selection Marker:
- PuroR
- Visible Reporter:
- n/a
- Epitope Tag:
- n/a
Additional Information:
- Addgene ID:
- 76877
Gene matches for this target sequence (CRISPRko, PAM=NGG, human):
| Reference Sequence |
Chromosome |
Cut Position |
Match Strand |
Match Gene |
Match Sequence |
PAM Seq. |
Mismatches[?]Genomic matches are found by querying with a reduced sequence corresponding to the final 17mer of the 20mer guide target sequence, combined with the `GG` of the PAM sequence. Mismatches are assessed within this set of bases only, for a total of 19 possible matching bases. |
CFD Score[?]Off target matches are assesed via a Cutting Frequency Determination, or CFD score. This value provides an estimate of how specific mismatches affect the likelihood that an sgRNA will cut a given target sequence. For more information, see Doench, Fusi et al., Nature Biotechnology 2016. |
Match Tier[?]For a description of CRISPR match tiers, see How the sgRNA Designer Works. |
1 |
NC_000001.11 |
1 |
232955648 |
+ |
NTPCR |
NNNACCGAAGAAGTCAGACA |
NGG |
0 |
1.0 |
Tier I |
2 |
NC_000006.12 |
6 |
130175898 |
- |
SAMD3 |
NNNACCGAAGAGGCCAGACA |
NGG |
2 |
0.2063 |
Tier I |
3 |
NC_000009.12 |
9 |
96818523 |
- |
ZNF782 |
NNNACCGAAGAACTCACACA |
NGG |
2 |
0.0991 |
Tier I |
4 |
NC_000014.9 |
14 |
76480919 |
- |
ESRRB |
NNNACACAAGAAGTCAGACA |
NGG |
2 |
0.6384 |
Tier II |
5 |
NC_000008.11 |
8 |
120598513 |
+ |
SNTB1 |
NNNAGTGAAGAAGTCAGACA |
NGG |
2 |
0.5571 |
Tier II |
6 |
NC_000015.10 |
15 |
74570364 |
- |
ARID3B |
NNNACCTAAAAAGTCAGACA |
NGG |
2 |
0.5333 |
Tier II |
7 |
NC_000007.14 |
7 |
114176652 |
- |
FOXP2 |
NNNACCTAAGAAATCAGACA |
NGG |
2 |
0.5275 |
Tier II |
8 |
NC_000012.12 |
12 |
100239973 |
- |
DEPDC4 |
NNNAACTAAGAAGTCAGACA |
NGG |
2 |
0.3265 |
Tier II |
9 |
NC_000011.10 |
11 |
20119591 |
- |
NAV2 |
NNNACCGAAGAGGTCAGGCA |
NGG |
2 |
0.2889 |
Tier II |
10 |
NC_000009.12 |
9 |
5768720 |
- |
RIC1 |
NNNACAGAAGAAGTCAGACC |
NGG |
2 |
0.211 |
Tier II |
11 |
NC_000004.12 |
4 |
13873048 |
- |
LINC01182 |
NNNACTAAAGAAGTCAGACA |
NGG |
2 |
0.9286 |
Tier III |
12 |
NC_000004.12 |
4 |
13873048 |
- |
LOC107986182 |
NNNACTAAAGAAGTCAGACA |
NGG |
2 |
0.9286 |
Tier III |
13 |
NC_000009.12 |
9 |
14931344 |
+ |
LOC124902122 |
NNNACAGTAGAAGTCAGACA |
NGG |
2 |
0.398 |
Tier III |
14 |
NC_000011.10 |
11 |
20119591 |
- |
LOC107984418 |
NNNACCGAAGAGGTCAGGCA |
NGG |
2 |
0.2889 |
Tier III |
15 |
NC_000014.9 |
14 |
49084416 |
- |
LOC105378178 |
NNNACAGAAGAAGTCAGAGA |
NGG |
2 |
0.1161 |
Tier III |
16 |
NC_000008.11 |
8 |
23745536 |
- |
LOC107986930 |
NNNACCCAAGAAGGCAGACA |
NGG |
2 |
0.0 |
Tier III |
Gene matches for this target sequence (CRISPRko, PAM=NGG, mouse):
| Reference Sequence |
Chromosome |
Cut Position |
Match Strand |
Match Gene |
Match Sequence |
PAM Seq. |
Mismatches[?]Genomic matches are found by querying with a reduced sequence corresponding to the final 17mer of the 20mer guide target sequence, combined with the `GG` of the PAM sequence. Mismatches are assessed within this set of bases only, for a total of 19 possible matching bases. |
CFD Score[?]Off target matches are assesed via a Cutting Frequency Determination, or CFD score. This value provides an estimate of how specific mismatches affect the likelihood that an sgRNA will cut a given target sequence. For more information, see Doench, Fusi et al., Nature Biotechnology 2016. |
Match Tier[?]For a description of CRISPR match tiers, see How the sgRNA Designer Works. |
1 |
NC_000072.6 |
6 |
101151450 |
- |
Pdzrn3 |
NNNGCCGGAGAAGTCAGACA |
NGG |
2 |
0.4583 |
Tier I |
2 |
NC_000076.6 |
10 |
26251860 |
+ |
Samd3 |
NNNACCGAAGAGGCCAGACA |
NGG |
2 |
0.2063 |
Tier I |
3 |
NC_000068.7 |
2 |
156038100 |
+ |
Fer1l4 |
NNNACTGAGGAAGTCAGACA |
NGG |
2 |
0.619 |
Tier II |
4 |
NC_000083.6 |
17 |
45534026 |
- |
Tcte1 |
NNNAACGAAGAAATCAGACA |
NGG |
2 |
0.5275 |
Tier II |
5 |
NC_000083.6 |
17 |
65936051 |
+ |
Twsg1 |
NNNTCCGAAGAAGACAGACA |
NGG |
2 |
0.3939 |
Tier II |
6 |
NC_000079.6 |
13 |
92477681 |
+ |
Fam151b |
NNNACTGAAGAAGTCAGGCA |
NGG |
2 |
0.3714 |
Tier II |
7 |
NC_000073.6 |
7 |
49608129 |
- |
Nav2 |
NNNACCGAAGAGGTCAGGCA |
NGG |
2 |
0.2889 |
Tier II |
8 |
NC_000077.6 |
11 |
93249303 |
+ |
Car10 |
NNNAAGGAAGAAGTCAGACA |
NGG |
2 |
0.2857 |
Tier II |
9 |
NC_000079.6 |
13 |
12305172 |
+ |
Actn2 |
NNNCCCCAAGAAGTCAGACA |
NGG |
2 |
0.2426 |
Tier II |
10 |
NC_000067.6 |
1 |
17023558 |
+ |
Jph1 |
NNNACCCAAGATGTCAGACA |
NGG |
2 |
0.2292 |
Tier II |
11 |
NC_000082.6 |
16 |
9589247 |
+ |
Grin2a |
NNNACCCAAGATGTCAGACA |
NGG |
2 |
0.2292 |
Tier II |
12 |
NC_000067.6 |
1 |
180906978 |
- |
Pycr2 |
NNNACGGAAGAACTCAGACA |
NGG |
2 |
0.2105 |
Tier II |
13 |
NC_000086.7 |
X |
83334750 |
- |
Dmd |
NNNACCGCAGAAGTCAGATA |
NGG |
2 |
0.1978 |
Tier II |
14 |
NC_000085.6 |
19 |
53613962 |
+ |
Smc3 |
NNNACCTAAGAAGTCATACA |
NGG |
2 |
0.1429 |
Tier II |
15 |
NC_000071.6 |
5 |
137762364 |
- |
Tsc22d4 |
NNNACCTAAGAAGTAAGACA |
NGG |
2 |
0.127 |
Tier II |
16 |
NC_000072.6 |
6 |
108541492 |
+ |
Itpr1 |
NNNACGGAAGAAGTCAGACC |
NGG |
2 |
0.1136 |
Tier II |
17 |
NC_000071.6 |
5 |
91393405 |
+ |
Btc |
NNNACCAAAGAAGTCAGACA |
NCG |
2 |
0.1071 |
Tier II |
18 |
NC_000072.6 |
6 |
28710145 |
- |
Snd1 |
NNNACCCAAGAAGTCAGACA |
NGT |
2 |
0.0111 |
Tier II |
19 |
NC_000070.6 |
4 |
142358081 |
+ |
Gm46875 |
NNNACAGAAGAATTCAGACA |
NGG |
2 |
0.2786 |
Tier III |
20 |
NC_000080.6 |
14 |
13234848 |
+ |
Gm5087 |
NNNACCTAAGAAGTTAGACA |
NGG |
2 |
0.0381 |
Tier III |
Other clones with same target sequence:
(none)