Construct: sgRNA BRDN0001148036
Construct Description:
- Construct Type:
- sgRNA
- Other Identifiers:
- n/a
- DNA Barcode:
- TAATACTCACAGGTGTAAGG
Original Target:
- Taxon:
-
Homo sapiens (human)
- Gene:
- FPGT-TNNI3K (100526835)
- Gene Description:
- n/a
- CRISPR Mechanism
- CRISPRko
Vector Information:
- Vector Backbone:
- pXPR_003
- Pol II Cassette 1:
- EF1A-PuroR
- Pol II Cassette 2:
- n/a
- Selection Marker:
- PuroR
- Visible Reporter:
- n/a
- Epitope Tag:
- n/a
Additional Information:
- Addgene ID:
- 75905
Gene matches for this target sequence (CRISPRko, PAM=NGG, human):
Gene matches for this target sequence (CRISPRko, PAM=NGG, mouse):
| Reference Sequence |
Chromosome |
Cut Position |
Match Strand |
Match Gene |
Match Sequence |
PAM Seq. |
Mismatches[?]Genomic matches are found by querying with a reduced sequence corresponding to the final 17mer of the 20mer guide target sequence, combined with the `GG` of the PAM sequence. Mismatches are assessed within this set of bases only, for a total of 19 possible matching bases. |
CFD Score[?]Off target matches are assesed via a Cutting Frequency Determination, or CFD score. This value provides an estimate of how specific mismatches affect the likelihood that an sgRNA will cut a given target sequence. For more information, see Doench, Fusi et al., Nature Biotechnology 2016. |
Match Tier[?]For a description of CRISPR match tiers, see How the sgRNA Designer Works. |
1 |
NC_000074.6 |
8 |
24711307 |
+ |
Adam3 |
NNNTACTCACAGGAGTAAGT |
NGG |
2 |
0.4333 |
Tier I |
2 |
NC_000084.6 |
18 |
63245578 |
+ |
Piezo2 |
NNNTACTCACAGTTGTAAGC |
NGG |
2 |
0.1286 |
Tier I |
3 |
NC_000067.6 |
1 |
191350836 |
+ |
Pacc1 |
NNNTACTCACAGGTATAAGG |
NGG |
1 |
0.9412 |
Tier II |
4 |
NC_000071.6 |
5 |
105096952 |
- |
Gbp9 |
NNNTACTGACAGGTGTAAGA |
NGG |
2 |
0.6027 |
Tier II |
5 |
NC_000069.6 |
3 |
139303907 |
- |
Stpg2 |
NNNTACTGACAGGTGAAAGG |
NGG |
2 |
0.5844 |
Tier II |
6 |
NC_000079.6 |
13 |
44868936 |
+ |
Jarid2 |
NNNTACACACAGGAGTAAGG |
NGG |
2 |
0.5417 |
Tier II |
7 |
NC_000067.6 |
1 |
175139160 |
+ |
Rgs7 |
NNNTACTCAAAGGAGTAAGG |
NGG |
2 |
0.5365 |
Tier II |
8 |
NC_000069.6 |
3 |
67339902 |
- |
Rsrc1 |
NNNTACTCACAGGTGCAAAG |
NGG |
2 |
0.4762 |
Tier II |
9 |
NC_000079.6 |
13 |
100085421 |
+ |
Bdp1 |
NNNTACTCACAGGAGTAAGT |
NGG |
2 |
0.4333 |
Tier II |
10 |
NC_000069.6 |
3 |
29999722 |
- |
Mecom |
NNNAACTCAAAGGTGTAAGG |
NGG |
2 |
0.4127 |
Tier II |
11 |
NC_000075.6 |
9 |
86665621 |
- |
Me1 |
NNNAACTGACAGGTGTAAGG |
NGG |
2 |
0.3061 |
Tier II |
12 |
NC_000083.6 |
17 |
55991782 |
+ |
Fsd1 |
NNNTACTCTCAGGTGTATGG |
NGG |
2 |
0.3 |
Tier II |
13 |
NC_000067.6 |
1 |
119753102 |
+ |
Ptpn4 |
NNNTTCTGACAGGTGTAAGG |
NGG |
2 |
0.2338 |
Tier II |
14 |
NC_000068.7 |
2 |
67863268 |
- |
B3galt1 |
NNNTTCTGACAGGTGTAAGG |
NGG |
2 |
0.2338 |
Tier II |
15 |
NC_000072.6 |
6 |
70780803 |
- |
Rpia |
NNNTTCTGACAGGTGTAAGG |
NGG |
2 |
0.2338 |
Tier II |
16 |
NC_000077.6 |
11 |
108565103 |
+ |
Cep112 |
NNNTTCTGACAGGTGTAAGG |
NGG |
2 |
0.2338 |
Tier II |
17 |
NC_000081.6 |
15 |
28325381 |
+ |
Dnah5 |
NNNTTCTGACAGGTGTAAGG |
NGG |
2 |
0.2338 |
Tier II |
18 |
NC_000086.7 |
X |
105986851 |
- |
Magt1 |
NNNTTCTGACAGGTGTAAGG |
NGG |
2 |
0.2338 |
Tier II |
19 |
NC_000070.6 |
4 |
104530078 |
+ |
Dab1 |
NNNTTCTCACAGGAGTAAGG |
NGG |
2 |
0.2251 |
Tier II |
20 |
NC_000079.6 |
13 |
91070230 |
- |
Atg10 |
NNNTACTGACTGGTGTAAGG |
NGG |
2 |
0.1978 |
Tier II |
21 |
NC_000068.7 |
2 |
28615515 |
- |
Gfi1b |
NNNTATTCACAGGTGTCAGG |
NGG |
2 |
0.1639 |
Tier II |
22 |
NC_000072.6 |
6 |
54608829 |
+ |
Plekha8 |
NNNTTCTCACTGGTGTAAGG |
NGG |
2 |
0.1119 |
Tier II |
23 |
NC_000086.7 |
X |
96445691 |
+ |
Hsf3 |
NNNTTCTCACTGGTGTAAGG |
NGG |
2 |
0.1119 |
Tier II |
24 |
NC_000080.6 |
14 |
29463447 |
- |
Cacna2d3 |
NNNGACTCACAGGTGTGAGG |
NGG |
2 |
0.1103 |
Tier II |
25 |
NC_000072.6 |
6 |
88576212 |
- |
Kbtbd12 |
NNNTACTCACAGGTGTTAGT |
NGG |
2 |
0.0933 |
Tier II |
26 |
NC_000079.6 |
13 |
119740351 |
- |
Nim1k |
NNNTACTCACAGGTATAAGG |
NGA |
2 |
0.0654 |
Tier II |
27 |
NC_000076.6 |
10 |
32080361 |
+ |
Nkain2 |
NNNTTCTCACAGGTGTGAGG |
NGG |
2 |
0.0642 |
Tier II |
28 |
NC_000080.6 |
14 |
87418029 |
+ |
Tdrd3 |
NNNTACTCACAGGTGTAAAG |
NTG |
2 |
0.0278 |
Tier II |
29 |
NC_000073.6 |
7 |
68316007 |
+ |
Fam169b |
NNNTACTCCCAGGTGTAAGG |
NTG |
2 |
0.0223 |
Tier II |
30 |
NC_000069.6 |
3 |
18383753 |
+ |
Gm30667 |
NNNTACTCACAGGTATAAGA |
NGG |
2 |
0.8824 |
Tier III |
31 |
NC_000067.6 |
1 |
74824470 |
- |
Gm32275 |
NNNTACTGACAGATGTAAGG |
NGG |
2 |
0.5934 |
Tier III |
32 |
NC_000069.6 |
3 |
29999722 |
- |
Gm52621 |
NNNAACTCAAAGGTGTAAGG |
NGG |
2 |
0.4127 |
Tier III |
33 |
NC_000072.6 |
6 |
70225563 |
- |
Igk |
NNNTTCTCACAGGTGTAAGA |
NGG |
2 |
0.3409 |
Tier III |
34 |
NC_000086.7 |
X |
11505023 |
+ |
Gm39496 |
NNNTACTCACATGTGTAAGT |
NGG |
2 |
0.2692 |
Tier III |
35 |
NC_000079.6 |
13 |
78552966 |
+ |
Gm32067 |
NNNTTCTGACAGGTGTAAGG |
NGG |
2 |
0.2338 |
Tier III |
36 |
NC_000085.6 |
19 |
39940273 |
- |
Cyp2c71-ps |
NNNTACTGACTGGTGTAAGG |
NGG |
2 |
0.1978 |
Tier III |
37 |
NC_000072.6 |
6 |
60120747 |
- |
Gm5570 |
NNNTACTGACAGGTGTGAGG |
NGG |
2 |
0.1134 |
Tier III |
38 |
NC_000068.7 |
2 |
13563756 |
+ |
Gm9875 |
NNNTTCTCACTGGTGTAAGG |
NGG |
2 |
0.1119 |
Tier III |
39 |
NC_000086.7 |
X |
148058711 |
- |
Gm15110 |
NNNTTCTCACTGGTGTAAGG |
NGG |
2 |
0.1119 |
Tier III |
40 |
NC_000086.7 |
X |
148378024 |
- |
Gm15113 |
NNNTTCTCACTGGTGTAAGG |
NGG |
2 |
0.1119 |
Tier III |
41 |
NC_000086.7 |
X |
148546964 |
- |
Gm15112 |
NNNTTCTCACTGGTGTAAGG |
NGG |
2 |
0.1119 |
Tier III |
42 |
NC_000086.7 |
X |
148729371 |
- |
Gm15126 |
NNNTTCTCACTGGTGTAAGG |
NGG |
2 |
0.1119 |
Tier III |
43 |
NC_000086.7 |
X |
148949985 |
- |
Gm15094 |
NNNTTCTCACTGGTGTAAGG |
NGG |
2 |
0.1119 |
Tier III |
44 |
NC_000086.7 |
X |
149161448 |
- |
Gm15090 |
NNNTTCTCACTGGTGTAAGG |
NGG |
2 |
0.1119 |
Tier III |
45 |
NC_000086.7 |
X |
149330547 |
- |
Gm15089 |
NNNTTCTCACTGGTGTAAGG |
NGG |
2 |
0.1119 |
Tier III |
Other clones with same target sequence:
(none)