Construct: sgRNA BRDN0001148069
Construct Description:
- Construct Type:
- sgRNA
- Other Identifiers:
- n/a
- DNA Barcode:
- CATGATCTCAGATTAGAGAG
Original Target:
- Taxon:
-
Homo sapiens (human)
- Gene:
- TEC (7006)
- Gene Description:
- n/a
- CRISPR Mechanism
- CRISPRko
Vector Information:
- Vector Backbone:
- pXPR_003
- Pol II Cassette 1:
- EF1A-PuroR
- Pol II Cassette 2:
- n/a
- Selection Marker:
- PuroR
- Visible Reporter:
- n/a
- Epitope Tag:
- n/a
Additional Information:
- Addgene ID:
- 77024
Gene matches for this target sequence (CRISPRko, PAM=NGG, human):
| Reference Sequence |
Chromosome |
Cut Position |
Match Strand |
Match Gene |
Match Sequence |
PAM Seq. |
Mismatches[?]Genomic matches are found by querying with a reduced sequence corresponding to the final 17mer of the 20mer guide target sequence, combined with the `GG` of the PAM sequence. Mismatches are assessed within this set of bases only, for a total of 19 possible matching bases. |
CFD Score[?]Off target matches are assesed via a Cutting Frequency Determination, or CFD score. This value provides an estimate of how specific mismatches affect the likelihood that an sgRNA will cut a given target sequence. For more information, see Doench, Fusi et al., Nature Biotechnology 2016. |
Match Tier[?]For a description of CRISPR match tiers, see How the sgRNA Designer Works. |
1 |
NC_000004.12 |
4 |
48167847 |
- |
TEC |
NNNGATCTCAGATTAGAGAG |
NGG |
0 |
1.0 |
Tier I |
2 |
NC_000008.11 |
8 |
68172638 |
- |
PREX2 |
NNNGATCTCAGATTAAAGAT |
NGG |
2 |
0.7 |
Tier II |
3 |
NC_000009.12 |
9 |
2049912 |
+ |
SMARCA2 |
NNNGATCAAAGATTAGAGAG |
NGG |
2 |
0.6857 |
Tier II |
4 |
NC_000019.10 |
19 |
50976461 |
- |
KLK7 |
NNNGATCTAAGATTGGAGAG |
NGG |
2 |
0.5571 |
Tier II |
5 |
NC_000010.11 |
10 |
128074022 |
- |
PTPRE |
NNNGATCACAGATTAGATAG |
NGG |
2 |
0.5333 |
Tier II |
6 |
NC_000013.11 |
13 |
25716392 |
- |
ATP8A2 |
NNNGATCTCAGATTAGACAA |
NGG |
2 |
0.4464 |
Tier II |
7 |
NC_000015.10 |
15 |
83712916 |
- |
ADAMTSL3 |
NNNGGTCTGAGATTAGAGAG |
NGG |
2 |
0.4457 |
Tier II |
8 |
NC_000021.9 |
21 |
25956939 |
- |
APP |
NNNGATCTCACATTAAAGAG |
NGG |
2 |
0.4286 |
Tier II |
9 |
NC_000002.12 |
2 |
30807371 |
+ |
CAPN13 |
NNNGCTCTCAGGTTAGAGAG |
NGG |
2 |
0.3611 |
Tier II |
10 |
NC_000002.12 |
2 |
172699945 |
+ |
PDK1 |
NNNTACCTCAGATTAGAGAG |
NGG |
2 |
0.3306 |
Tier II |
11 |
NC_000012.12 |
12 |
56770112 |
+ |
HSD17B6 |
NNNGCTCTCAGATTGGAGAG |
NGG |
2 |
0.325 |
Tier II |
12 |
NC_000011.10 |
11 |
70774677 |
+ |
SHANK2 |
NNNGCTCTGAGATTAGAGAG |
NGG |
2 |
0.3095 |
Tier II |
13 |
NC_000011.10 |
11 |
33411232 |
- |
KIAA1549L |
NNNCATCTCAGATTAGAGGG |
NGG |
2 |
0.1985 |
Tier II |
14 |
NC_000003.12 |
3 |
30612443 |
+ |
TGFBR2 |
NNNGATATCAGATTTGAGAG |
NGG |
2 |
0.15 |
Tier II |
15 |
NC_000003.12 |
3 |
134985618 |
- |
EPHB1 |
NNNGATCTCATTTTAGAGAG |
NGG |
2 |
0.1282 |
Tier II |
16 |
NC_000009.12 |
9 |
72749015 |
- |
TMC1 |
NNNGTTCTCAGATTTGAGAG |
NGG |
2 |
0.0727 |
Tier II |
17 |
NC_000005.10 |
5 |
72153278 |
+ |
MAP1B |
NNNGATCTCACATGAGAGAG |
NGG |
2 |
0.0 |
Tier II |
18 |
NC_000014.9 |
14 |
59349680 |
+ |
DAAM1 |
NNNGATCTCAGATGAGAGAG |
NGA |
2 |
0.0 |
Tier II |
19 |
NC_000005.10 |
5 |
164488199 |
+ |
LOC102546299 |
NNNGACCTCAGATAAGAGAG |
NGG |
2 |
0.5628 |
Tier III |
20 |
NC_000005.10 |
5 |
164488199 |
+ |
LINC03000 |
NNNGACCTCAGATAAGAGAG |
NGG |
2 |
0.5628 |
Tier III |
21 |
NC_000011.10 |
11 |
109764615 |
+ |
LINC02715 |
NNNGCTCTGAGATTAGAGAG |
NGG |
2 |
0.3095 |
Tier III |
22 |
NC_000016.10 |
16 |
80841901 |
+ |
ARLNC1 |
NNNGATCTCACCTTAGAGAG |
NGG |
2 |
0.1128 |
Tier III |
23 |
NC_000021.9 |
21 |
18577777 |
- |
MIR548XHG |
NNNGATCTCAGTGTAGAGAG |
NGG |
2 |
0.087 |
Tier III |
24 |
NC_000004.12 |
4 |
18743200 |
- |
LOC105374510 |
NNNGATTTCAGATTAGAGAG |
NTG |
2 |
0.0317 |
Tier III |
25 |
NC_000014.9 |
14 |
29187863 |
+ |
LOC107984685 |
NNNGTTCTCAGATTAGAGAG |
NGA |
2 |
0.0253 |
Tier III |
26 |
NC_000005.10 |
5 |
147187263 |
+ |
STK32A-AS1 |
NNNGATCTCAGATTACAGAG |
NGA |
2 |
0.0 |
Tier III |
Gene matches for this target sequence (CRISPRko, PAM=NGG, mouse):
| Reference Sequence |
Chromosome |
Cut Position |
Match Strand |
Match Gene |
Match Sequence |
PAM Seq. |
Mismatches[?]Genomic matches are found by querying with a reduced sequence corresponding to the final 17mer of the 20mer guide target sequence, combined with the `GG` of the PAM sequence. Mismatches are assessed within this set of bases only, for a total of 19 possible matching bases. |
CFD Score[?]Off target matches are assesed via a Cutting Frequency Determination, or CFD score. This value provides an estimate of how specific mismatches affect the likelihood that an sgRNA will cut a given target sequence. For more information, see Doench, Fusi et al., Nature Biotechnology 2016. |
Match Tier[?]For a description of CRISPR match tiers, see How the sgRNA Designer Works. |
1 |
NC_000071.6 |
5 |
72782072 |
- |
Tec |
NNNGACCTCAGGTTAGAGAG |
NGG |
2 |
0.6566 |
Tier I |
2 |
NC_000077.6 |
11 |
77274159 |
+ |
Ssh2 |
NNNGACCTCAAATTAGAGAG |
NGG |
2 |
0.9091 |
Tier II |
3 |
NC_000075.6 |
9 |
84004563 |
+ |
Bckdhb |
NNNGATCTCTAATTAGAGAG |
NGG |
2 |
0.8824 |
Tier II |
4 |
NC_000071.6 |
5 |
31700721 |
+ |
Babam2 |
NNNGACCTTAGATTAGAGAG |
NGG |
2 |
0.7955 |
Tier II |
5 |
NC_000070.6 |
4 |
46003084 |
+ |
Tdrd7 |
NNNGACCTCAGACTAGAGAG |
NGG |
2 |
0.7177 |
Tier II |
6 |
NC_000069.6 |
3 |
83225115 |
- |
Dchs2 |
NNNGATCTAAGGTTAGAGAG |
NGG |
2 |
0.619 |
Tier II |
7 |
NC_000085.6 |
19 |
24731697 |
- |
Pgm5 |
NNNGATCTCAGGCTAGAGAG |
NGG |
2 |
0.5702 |
Tier II |
8 |
NC_000080.6 |
14 |
70479786 |
+ |
Bmp1 |
NNNGAGTTCAGATTAGAGAG |
NGG |
2 |
0.4643 |
Tier II |
9 |
NC_000082.6 |
16 |
40831396 |
+ |
Lsamp |
NNNCATCACAGATTAGAGAG |
NGG |
2 |
0.4235 |
Tier II |
10 |
NC_000084.6 |
18 |
5296235 |
- |
Zfp438 |
NNNGAGCTGAGATTAGAGAG |
NGG |
2 |
0.3537 |
Tier II |
11 |
NC_000067.6 |
1 |
118394264 |
- |
Clasp1 |
NNNGATGTCAGGTTAGAGAG |
NGG |
2 |
0.3399 |
Tier II |
12 |
NC_000071.6 |
5 |
149578900 |
+ |
Wdr95 |
NNNTATTTCAGATTAGAGAG |
NGG |
2 |
0.2955 |
Tier II |
13 |
NC_000081.6 |
15 |
80627248 |
- |
Grap2 |
NNNTATATCAGATTAGAGAG |
NGG |
2 |
0.2727 |
Tier II |
14 |
NC_000067.6 |
1 |
163309705 |
- |
Prrx1 |
NNNGAGCTCAGATTAGAGAC |
NGG |
2 |
0.2449 |
Tier II |
15 |
NC_000069.6 |
3 |
65064457 |
- |
Kcnab1 |
NNNAATCTCAGCTTAGAGAG |
NGG |
2 |
0.2368 |
Tier II |
16 |
NC_000069.6 |
3 |
68580262 |
+ |
Schip1 |
NNNGATCTCAGGGTAGAGAG |
NGG |
2 |
0.1884 |
Tier II |
17 |
NC_000069.6 |
3 |
68580262 |
+ |
Iqschfp |
NNNGATCTCAGGGTAGAGAG |
NGG |
2 |
0.1884 |
Tier II |
18 |
NC_000070.6 |
4 |
117960675 |
- |
St3gal3 |
NNNGGTCTCAGATTAGCGAG |
NGG |
2 |
0.1271 |
Tier II |
19 |
NC_000072.6 |
6 |
135148279 |
- |
Hebp1 |
NNNGATCTCAGAATAGTGAG |
NGG |
2 |
0.0923 |
Tier II |
20 |
NC_000077.6 |
11 |
59175795 |
+ |
Gjc2 |
NNNGATCTCAGCTCAGAGAG |
NGG |
2 |
0.0752 |
Tier II |
21 |
NC_000085.6 |
19 |
46692844 |
+ |
Borcs7 |
NNNGATCTCAGAGCAGAGAG |
NGG |
2 |
0.0745 |
Tier II |
22 |
NC_000073.6 |
7 |
43783905 |
+ |
Klk10 |
NNNGATCTAAGATTAGAGAG |
NTG |
2 |
0.0334 |
Tier II |
23 |
NC_000069.6 |
3 |
109650490 |
+ |
Vav3 |
NNNGATCTGAGATGAGAGAG |
NGG |
2 |
0.0 |
Tier II |
24 |
NC_000075.6 |
9 |
84004563 |
+ |
Gm46124 |
NNNGATCTCTAATTAGAGAG |
NGG |
2 |
0.8824 |
Tier III |
25 |
NC_000071.6 |
5 |
149578900 |
+ |
Gm35763 |
NNNTATTTCAGATTAGAGAG |
NGG |
2 |
0.2955 |
Tier III |
26 |
NC_000086.7 |
X |
5816359 |
+ |
LOC115489152 |
NNNCATCTCAGATTAGAGGG |
NGG |
2 |
0.1985 |
Tier III |
27 |
NC_000080.6 |
14 |
21997277 |
+ |
A330001L22Rik |
NNNGTTCTCAGTTTAGAGAG |
NGG |
2 |
0.1212 |
Tier III |
Other clones with same target sequence:
(none)