Construct: sgRNA BRDN0001148335
Construct Description:
- Construct Type:
- sgRNA
- Other Identifiers:
- n/a
- DNA Barcode:
- AGCCCCATAGGAAAACATCA
Original Target:
- Taxon:
-
Homo sapiens (human)
- Gene:
- PIK3C2G (5288)
- Gene Description:
- n/a
- CRISPR Mechanism
- CRISPRko
Vector Information:
- Vector Backbone:
- pXPR_003
- Pol II Cassette 1:
- EF1A-PuroR
- Pol II Cassette 2:
- n/a
- Selection Marker:
- PuroR
- Visible Reporter:
- n/a
- Epitope Tag:
- n/a
Additional Information:
- Addgene ID:
- 75740
Gene matches for this target sequence (CRISPRko, PAM=NGG, human):
Gene matches for this target sequence (CRISPRko, PAM=NGG, mouse):
| Reference Sequence |
Chromosome |
Cut Position |
Match Strand |
Match Gene |
Match Sequence |
PAM Seq. |
Mismatches[?]Genomic matches are found by querying with a reduced sequence corresponding to the final 17mer of the 20mer guide target sequence, combined with the `GG` of the PAM sequence. Mismatches are assessed within this set of bases only, for a total of 19 possible matching bases. |
CFD Score[?]Off target matches are assesed via a Cutting Frequency Determination, or CFD score. This value provides an estimate of how specific mismatches affect the likelihood that an sgRNA will cut a given target sequence. For more information, see Doench, Fusi et al., Nature Biotechnology 2016. |
Match Tier[?]For a description of CRISPR match tiers, see How the sgRNA Designer Works. |
1 |
NC_000068.7 |
2 |
26222336 |
- |
Qsox2 |
NNNTCCATATGAAAACATCA |
NGG |
2 |
0.65 |
Tier I |
2 |
NC_000080.6 |
14 |
96280209 |
- |
Klhl1 |
NNNCCCACAGGAAAACATAA |
NGG |
2 |
0.4286 |
Tier I |
3 |
NC_000072.6 |
6 |
13193119 |
+ |
Vwde |
NNNCCCACAGGAAAACATCA |
NTG |
2 |
0.039 |
Tier I |
4 |
NC_000076.6 |
10 |
30673776 |
- |
Ncoa7 |
NNNCCAATAGGAAAACATCA |
NGG |
1 |
0.9286 |
Tier II |
5 |
NC_000078.6 |
12 |
102625009 |
+ |
Itpk1 |
NNNCCAATAAGAAAACATCA |
NGG |
2 |
0.8667 |
Tier II |
6 |
NC_000068.7 |
2 |
20022440 |
- |
Etl4 |
NNNCCTAAAGGAAAACATCA |
NGG |
2 |
0.7429 |
Tier II |
7 |
NC_000072.6 |
6 |
142402764 |
- |
Golt1b |
NNNCCGACAGGAAAACATCA |
NGG |
2 |
0.5 |
Tier II |
8 |
NC_000072.6 |
6 |
48571272 |
- |
Rarres2 |
NNNCCCATATGAAAACATCT |
NGG |
2 |
0.4875 |
Tier II |
9 |
NC_000068.7 |
2 |
120752571 |
+ |
Ttbk2 |
NNNCCCACAGCAAAACATCA |
NGG |
2 |
0.4286 |
Tier II |
10 |
NC_000077.6 |
11 |
110287231 |
- |
Abca5 |
NNNCCCACAGGAAAACATAA |
NGG |
2 |
0.4286 |
Tier II |
11 |
NC_000077.6 |
11 |
93304052 |
+ |
Car10 |
NNNCCCATAGAAAAACACCA |
NGG |
2 |
0.4286 |
Tier II |
12 |
NC_000067.6 |
1 |
12767012 |
- |
Sulf1 |
NNNCTCATAGGAAAACAACA |
NGG |
2 |
0.4242 |
Tier II |
13 |
NC_000067.6 |
1 |
115788650 |
- |
Cntnap5a |
NNNCTCATAGGAAAACATCT |
NGG |
2 |
0.3818 |
Tier II |
14 |
NC_000075.6 |
9 |
8586559 |
- |
Trpc6 |
NNNCCCCTGGGAAAACATCA |
NGG |
2 |
0.2917 |
Tier II |
15 |
NC_000075.6 |
9 |
79988182 |
- |
Filip1 |
NNNCCAATAGGAAAACATCA |
NAG |
2 |
0.2407 |
Tier II |
16 |
NC_000084.6 |
18 |
58011498 |
- |
Fbn2 |
NNNCCCATAGCAAAACATTA |
NGG |
2 |
0.1978 |
Tier II |
17 |
NC_000076.6 |
10 |
120192524 |
+ |
Irak3 |
NNNCCCATAGGAAAACACAA |
NGG |
2 |
0.1837 |
Tier II |
18 |
NC_000075.6 |
9 |
55156996 |
- |
Ube2q2 |
NNNCCTATAGGAAAACTTCA |
NGG |
2 |
0.1238 |
Tier II |
19 |
NC_000070.6 |
4 |
32419510 |
- |
Bach2 |
NNNCCCATAGCCAAACATCA |
NGG |
2 |
0.1128 |
Tier II |
20 |
NC_000077.6 |
11 |
3329823 |
- |
Pik3ip1 |
NNNGCCATAGGAAAACTTCA |
NGG |
2 |
0.0667 |
Tier II |
21 |
NC_000075.6 |
9 |
121474117 |
+ |
Trak1 |
NNNCCCATAGGAAAAGATCA |
NAG |
2 |
0.0399 |
Tier II |
22 |
NC_000070.6 |
4 |
118221702 |
+ |
Ptprf |
NNNCCCATAGGACAACCTCA |
NGG |
2 |
0.0372 |
Tier II |
23 |
NC_000086.7 |
X |
53259733 |
- |
Fam122b |
NNNCCCATAGGAAAAGCTCA |
NGG |
2 |
0.0271 |
Tier II |
24 |
NC_000074.6 |
8 |
28921567 |
- |
Unc5d |
NNNCCCATAGGAAAACATGA |
NTG |
2 |
0.0049 |
Tier II |
25 |
NC_000085.6 |
19 |
20439242 |
+ |
Gm41816 |
NNNCCTATAGGAAAATATCA |
NGG |
2 |
0.2857 |
Tier III |
26 |
NC_000083.6 |
17 |
31750163 |
- |
Gm30316 |
NNNCCCATAGCAAGACATCA |
NGG |
2 |
0.2 |
Tier III |
27 |
NC_000076.6 |
10 |
120192524 |
+ |
Gm40781 |
NNNCCCATAGGAAAACACAA |
NGG |
2 |
0.1837 |
Tier III |
28 |
NC_000077.6 |
11 |
3329823 |
- |
Gm12592 |
NNNGCCATAGGAAAACTTCA |
NGG |
2 |
0.0667 |
Tier III |
29 |
NC_000073.6 |
7 |
119615522 |
- |
Gm39079 |
NNNCCCATAGGAAGACATCA |
NTG |
2 |
0.0182 |
Tier III |
Other clones with same target sequence:
(none)