Construct: sgRNA BRDN0001148856
Construct Description:
- Construct Type:
- sgRNA
- Other Identifiers:
- n/a
- DNA Barcode:
- GACTGTAGCCAAGCTCACAT
Original Target:
- Taxon:
-
Homo sapiens (human)
- Gene:
- STK38L (23012)
- Gene Description:
- n/a
- CRISPR Mechanism
- CRISPRko
Vector Information:
- Vector Backbone:
- pXPR_003
- Pol II Cassette 1:
- EF1A-PuroR
- Pol II Cassette 2:
- n/a
- Selection Marker:
- PuroR
- Visible Reporter:
- n/a
- Epitope Tag:
- n/a
Additional Information:
- Addgene ID:
- 76628
Gene matches for this target sequence (CRISPRko, PAM=NGG, human):
| Reference Sequence |
Chromosome |
Cut Position |
Match Strand |
Match Gene |
Match Sequence |
PAM Seq. |
Mismatches[?]Genomic matches are found by querying with a reduced sequence corresponding to the final 17mer of the 20mer guide target sequence, combined with the `GG` of the PAM sequence. Mismatches are assessed within this set of bases only, for a total of 19 possible matching bases. |
CFD Score[?]Off target matches are assesed via a Cutting Frequency Determination, or CFD score. This value provides an estimate of how specific mismatches affect the likelihood that an sgRNA will cut a given target sequence. For more information, see Doench, Fusi et al., Nature Biotechnology 2016. |
Match Tier[?]For a description of CRISPR match tiers, see How the sgRNA Designer Works. |
1 |
NC_000012.12 |
12 |
27297800 |
+ |
STK38L |
NNNTGTAGCCAAGCTCACAT |
NGG |
0 |
1.0 |
Tier I |
2 |
NC_000005.10 |
5 |
138290638 |
+ |
CDC25C |
NNNTGTAGCCAAACTCACCT |
NGG |
2 |
0.191 |
Tier I |
3 |
NC_000020.11 |
20 |
36207987 |
- |
EPB41L1 |
NNNTGTGGCCAAGCTAACAT |
NGG |
2 |
0.7059 |
Tier II |
4 |
NC_000010.11 |
10 |
110783738 |
+ |
RBM20 |
NNNTGTAGTCAAGTTCACAT |
NGG |
2 |
0.6417 |
Tier II |
5 |
NC_000006.12 |
6 |
36892826 |
+ |
C6orf89 |
NNNTGTAGCAAAGCTCACTT |
NGG |
2 |
0.4667 |
Tier II |
6 |
NC_000016.10 |
16 |
28616742 |
- |
SULT1A1 |
NNNTGTAGCCAAGTTCACAT |
NAG |
2 |
0.1901 |
Tier II |
7 |
NC_000018.10 |
18 |
59345899 |
- |
LMAN1 |
NNNTGTAGCAAAGCTGACAT |
NGG |
2 |
0.1333 |
Tier II |
8 |
NC_000017.11 |
17 |
51634623 |
+ |
CA10 |
NNNTGTAGCCAAGCTCACAC |
NGG |
1 |
0.0909 |
Tier II |
9 |
NC_000007.14 |
7 |
50611913 |
+ |
GRB10 |
NNNTTTAGCCAAGCTCACCT |
NGG |
2 |
0.0621 |
Tier II |
10 |
NC_000009.12 |
9 |
81683475 |
- |
TLE1 |
NNNTGTAGCCAAGCTCAAAT |
NGA |
2 |
0.0374 |
Tier II |
11 |
NC_000007.14 |
7 |
49940029 |
- |
ZPBP |
NNNTGTAGCCAAGCTCTGAT |
NGG |
2 |
0.0178 |
Tier II |
12 |
NC_000004.12 |
4 |
7684225 |
- |
SORCS2 |
NNNTGTAGCCAAGATCACAT |
NGT |
2 |
0.0056 |
Tier II |
13 |
NC_000002.12 |
2 |
134502170 |
+ |
TMEM163 |
NNNTGTAGCCAAGCTCACAT |
NAA |
2 |
0.0 |
Tier II |
14 |
NC_000001.11 |
1 |
243956501 |
- |
LINC02774 |
NNNTGTATCCAAGCTCACAT |
NGG |
1 |
0.625 |
Tier III |
15 |
NC_000002.12 |
2 |
14330495 |
- |
LINC00276 |
NNNTCTGGCCAAGCTCACAT |
NGG |
2 |
0.5546 |
Tier III |
16 |
NC_000010.11 |
10 |
89925720 |
+ |
LINC01375 |
NNNTGTAGCAAAGCTTACAT |
NGG |
2 |
0.2667 |
Tier III |
17 |
NC_000016.10 |
16 |
28616742 |
- |
LOC107984835 |
NNNTGTAGCCAAGTTCACAT |
NAG |
2 |
0.1901 |
Tier III |
Gene matches for this target sequence (CRISPRko, PAM=NGG, mouse):
| Reference Sequence |
Chromosome |
Cut Position |
Match Strand |
Match Gene |
Match Sequence |
PAM Seq. |
Mismatches[?]Genomic matches are found by querying with a reduced sequence corresponding to the final 17mer of the 20mer guide target sequence, combined with the `GG` of the PAM sequence. Mismatches are assessed within this set of bases only, for a total of 19 possible matching bases. |
CFD Score[?]Off target matches are assesed via a Cutting Frequency Determination, or CFD score. This value provides an estimate of how specific mismatches affect the likelihood that an sgRNA will cut a given target sequence. For more information, see Doench, Fusi et al., Nature Biotechnology 2016. |
Match Tier[?]For a description of CRISPR match tiers, see How the sgRNA Designer Works. |
1 |
NC_000072.6 |
6 |
146758551 |
+ |
Stk38l |
NNNTGTGGCCAAGCTCACAC |
NGG |
2 |
0.0642 |
Tier I |
2 |
NC_000083.6 |
17 |
14329145 |
- |
Smoc2 |
NNNGGTAGCAAAGCTCACAT |
NGG |
2 |
0.5417 |
Tier II |
3 |
NC_000070.6 |
4 |
107022790 |
- |
Ssbp3 |
NNNTGTGGCCAAGCTCACAA |
NGG |
2 |
0.3971 |
Tier II |
4 |
NC_000071.6 |
5 |
19621637 |
+ |
Magi2 |
NNNTGAAGCCAACCTCACAT |
NGG |
2 |
0.3649 |
Tier II |
5 |
NC_000073.6 |
7 |
134140568 |
- |
Adam12 |
NNNTGCAGCCAAGATCACAT |
NGG |
2 |
0.3182 |
Tier II |
6 |
NC_000074.6 |
8 |
16933654 |
+ |
Csmd1 |
NNNGGTTGCCAAGCTCACAT |
NGG |
2 |
0.2734 |
Tier II |
7 |
NC_000082.6 |
16 |
6676499 |
+ |
Rbfox1 |
NNNTGTACCCATGCTCACAT |
NGG |
2 |
0.2051 |
Tier II |
8 |
NC_000067.6 |
1 |
98457847 |
+ |
Slco6d1 |
NNNTGTGGCCAAGCTCACAC |
NGG |
2 |
0.0642 |
Tier II |
9 |
NC_000079.6 |
13 |
41171881 |
- |
Sycp2l |
NNNTCTAGCCAAGCTCACAT |
NGA |
2 |
0.0546 |
Tier II |
10 |
NC_000072.6 |
6 |
39011635 |
+ |
Tbxas1 |
NNNTGTAGCCAAGTGCACAT |
NGG |
2 |
0.0367 |
Tier II |
11 |
NC_000079.6 |
13 |
104390741 |
- |
Adamts6 |
NNNAGTAGCCAAGCTCACAT |
NGA |
2 |
0.0331 |
Tier II |
12 |
NC_000080.6 |
14 |
22795693 |
+ |
Lrmda |
NNNTGTAGCCAAGCTCACAT |
NGC |
1 |
0.0222 |
Tier II |
13 |
NC_000076.6 |
10 |
87926228 |
+ |
Igf1 |
NNNTGTAGCCAAGCTGACAT |
NGT |
2 |
0.0025 |
Tier II |
14 |
NC_000081.6 |
15 |
72718294 |
- |
Trappc9 |
NNNGGTAGCCAAGGTCACAT |
NGG |
2 |
0.0 |
Tier II |
15 |
NC_000080.6 |
14 |
60614465 |
+ |
Spata13 |
NNNTGGAGCCAAGGTCACAT |
NGG |
2 |
0.0 |
Tier II |
16 |
NC_000075.6 |
9 |
42805485 |
- |
Grik4 |
NNNTGTAGCCAAGGTCACAT |
NGT |
2 |
0.0 |
Tier II |
17 |
NC_000067.6 |
1 |
170521701 |
- |
Nos1ap |
NNNTGTAGCCCAGGTCACAT |
NGG |
2 |
0.0 |
Tier II |
18 |
NC_000067.6 |
1 |
82488737 |
+ |
Col4a4 |
NNNTGTAGCCGAGGTCACAT |
NGG |
2 |
0.0 |
Tier II |
19 |
NC_000083.6 |
17 |
31868568 |
- |
Gm30509 |
NNNTGTAGACAAGCTCAAAT |
NGG |
2 |
0.4615 |
Tier III |
20 |
NC_000070.6 |
4 |
107022790 |
- |
Gm12786 |
NNNTGTGGCCAAGCTCACAA |
NGG |
2 |
0.3971 |
Tier III |
21 |
NC_000067.6 |
1 |
98457847 |
+ |
Gm3555 |
NNNTGTGGCCAAGCTCACAC |
NGG |
2 |
0.0642 |
Tier III |
22 |
NC_000074.6 |
8 |
4641544 |
+ |
Gm7451 |
NNNTGTGGCCAAGCTCACAC |
NGG |
2 |
0.0642 |
Tier III |
23 |
NC_000080.6 |
14 |
22795693 |
+ |
Gm30926 |
NNNTGTAGCCAAGCTCACAT |
NGC |
1 |
0.0222 |
Tier III |
Other clones with same target sequence:
(none)