Construct: sgRNA BRDN0001149130
Construct Description:
- Construct Type:
- sgRNA
- Other Identifiers:
- n/a
- DNA Barcode:
- GCTTCTTGCTCCAATCAACA
Original Target:
- Taxon:
-
Homo sapiens (human)
- Gene:
- BLK (640)
- Gene Description:
- n/a
- CRISPR Mechanism
- CRISPRko
Vector Information:
- Vector Backbone:
- pXPR_003
- Pol II Cassette 1:
- EF1A-PuroR
- Pol II Cassette 2:
- n/a
- Selection Marker:
- PuroR
- Visible Reporter:
- n/a
- Epitope Tag:
- n/a
Additional Information:
- Addgene ID:
- 75751
Gene matches for this target sequence (CRISPRko, PAM=NGG, human):
Gene matches for this target sequence (CRISPRko, PAM=NGG, mouse):
| Reference Sequence |
Chromosome |
Cut Position |
Match Strand |
Match Gene |
Match Sequence |
PAM Seq. |
Mismatches[?]Genomic matches are found by querying with a reduced sequence corresponding to the final 17mer of the 20mer guide target sequence, combined with the `GG` of the PAM sequence. Mismatches are assessed within this set of bases only, for a total of 19 possible matching bases. |
CFD Score[?]Off target matches are assesed via a Cutting Frequency Determination, or CFD score. This value provides an estimate of how specific mismatches affect the likelihood that an sgRNA will cut a given target sequence. For more information, see Doench, Fusi et al., Nature Biotechnology 2016. |
Match Tier[?]For a description of CRISPR match tiers, see How the sgRNA Designer Works. |
1 |
NC_000081.6 |
15 |
30658777 |
+ |
Ctnnd2 |
NNNTCTTAATCCAATCAACA |
NGG |
2 |
0.8571 |
Tier II |
2 |
NC_000074.6 |
8 |
122431578 |
- |
Cyba |
NNNTCTAGGTCCAATCAACA |
NGG |
2 |
0.5417 |
Tier II |
3 |
NC_000077.6 |
11 |
64024199 |
- |
Cox10 |
NNNTCTTGCTCCATTCAACA |
NGG |
1 |
0.5333 |
Tier II |
4 |
NC_000082.6 |
16 |
45179500 |
- |
Atg3 |
NNNTGTTCCTCCAATCAACA |
NGG |
2 |
0.3692 |
Tier II |
5 |
NC_000074.6 |
8 |
28975796 |
+ |
Unc5d |
NNNTCTAGCTCCAATCAGCA |
NGG |
2 |
0.35 |
Tier II |
6 |
NC_000078.6 |
12 |
51755256 |
- |
Hectd1 |
NNNTCTTACTCCAACCAACA |
NGG |
2 |
0.2727 |
Tier II |
7 |
NC_000077.6 |
11 |
22072853 |
+ |
Ehbp1 |
NNNTCTTGCTCCAATAAACA |
NAG |
2 |
0.2593 |
Tier II |
8 |
NC_000078.6 |
12 |
110478896 |
+ |
Ppp2r5c |
NNNACTTGCTCGAATCAACA |
NGG |
2 |
0.2116 |
Tier II |
9 |
NC_000083.6 |
17 |
35963080 |
+ |
Abcf1 |
NNNTCTTGCTCCAGTCAGCA |
NGG |
2 |
0.1867 |
Tier II |
10 |
NC_000071.6 |
5 |
27593434 |
+ |
Dpp6 |
NNNTCTTGCTTCAATCAAAA |
NGG |
2 |
0.1319 |
Tier II |
11 |
NC_000073.6 |
7 |
92125788 |
- |
Dlg2 |
NNNTCTTTCTCCAATCAACA |
NTG |
2 |
0.0244 |
Tier II |
12 |
NC_000084.6 |
18 |
65730993 |
+ |
Oacyl |
NNNTGTTGCTCCAATCAACA |
NGT |
2 |
0.0097 |
Tier II |
13 |
NC_000070.6 |
4 |
10702966 |
+ |
1700123O12Rik |
NNNTTTTGCTCCAATCAACA |
NGG |
1 |
0.6364 |
Tier III |
14 |
NC_000070.6 |
4 |
128922070 |
+ |
Gm33901 |
NNNTCTTTCTCCAAACAACA |
NGG |
2 |
0.3618 |
Tier III |
15 |
NC_000073.6 |
7 |
100169116 |
+ |
Gm39057 |
NNNTCTTGCTCCATTCAAAA |
NGG |
2 |
0.2286 |
Tier III |
16 |
NC_000078.6 |
12 |
110478896 |
+ |
Gm19605 |
NNNACTTGCTCGAATCAACA |
NGG |
2 |
0.2116 |
Tier III |
17 |
NC_000078.6 |
12 |
73506989 |
+ |
Gm34016 |
NNNTCTTGCTCCATTCAACA |
NAG |
2 |
0.1383 |
Tier III |
18 |
NC_000084.6 |
18 |
55424440 |
- |
Gm34233 |
NNNACTTGCTCCAATGAACA |
NGG |
2 |
0.0733 |
Tier III |
19 |
NC_000076.6 |
10 |
117414022 |
+ |
Gm40770 |
NNNTCTTGCTCCAACCCACA |
NGG |
2 |
0.0481 |
Tier III |
Other clones with same target sequence:
(none)