Construct: sgRNA BRDN0001149539
Construct Description:
- Construct Type:
- sgRNA
- Other Identifiers:
- n/a
- DNA Barcode:
- GAAATACCTATTGAAAACCC
Original Target:
- Taxon:
-
Homo sapiens (human)
- Gene:
- PIK3C2G (5288)
- Gene Description:
- n/a
- CRISPR Mechanism
- CRISPRko
Vector Information:
- Vector Backbone:
- pXPR_003
- Pol II Cassette 1:
- EF1A-PuroR
- Pol II Cassette 2:
- n/a
- Selection Marker:
- PuroR
- Visible Reporter:
- n/a
- Epitope Tag:
- n/a
Additional Information:
- Addgene ID:
- 75741
Gene matches for this target sequence (CRISPRko, PAM=NGG, human):
| Reference Sequence |
Chromosome |
Cut Position |
Match Strand |
Match Gene |
Match Sequence |
PAM Seq. |
Mismatches[?]Genomic matches are found by querying with a reduced sequence corresponding to the final 17mer of the 20mer guide target sequence, combined with the `GG` of the PAM sequence. Mismatches are assessed within this set of bases only, for a total of 19 possible matching bases. |
CFD Score[?]Off target matches are assesed via a Cutting Frequency Determination, or CFD score. This value provides an estimate of how specific mismatches affect the likelihood that an sgRNA will cut a given target sequence. For more information, see Doench, Fusi et al., Nature Biotechnology 2016. |
Match Tier[?]For a description of CRISPR match tiers, see How the sgRNA Designer Works. |
1 |
NC_000012.12 |
12 |
18325094 |
+ |
PIK3C2G |
NNNATACCTATTGAAAACCC |
NGG |
0 |
1.0 |
Tier I |
2 |
NC_000007.14 |
7 |
74999470 |
+ |
CASTOR2 |
NNNAGACCCATTGAAAACCC |
NGG |
2 |
0.5908 |
Tier II |
3 |
NC_000005.10 |
5 |
155999195 |
- |
SGCD |
NNNATATCTACTGAAAACCC |
NGG |
2 |
0.5417 |
Tier II |
4 |
NC_000012.12 |
12 |
39962681 |
- |
SLC2A13 |
NNNATATCTATTGAAAAACC |
NGG |
2 |
0.4375 |
Tier II |
5 |
NC_000019.10 |
19 |
45532159 |
+ |
OPA3 |
NNNATCCCTATTAAAAACCC |
NGG |
2 |
0.4196 |
Tier II |
6 |
NC_000003.12 |
3 |
128243595 |
+ |
EEFSEC |
NNNATACAGATTGAAAACCC |
NGG |
2 |
0.4024 |
Tier II |
7 |
NC_000019.10 |
19 |
31221281 |
- |
TSHZ3 |
NNNATATCTATTGGAAACCC |
NGG |
2 |
0.3792 |
Tier II |
8 |
NC_000005.10 |
5 |
94411185 |
+ |
KIAA0825 |
NNNATACATATTGTAAACCC |
NGG |
2 |
0.3467 |
Tier II |
9 |
NC_000017.11 |
17 |
55125465 |
+ |
STXBP4 |
NNNAAACCTATTGTAAACCC |
NGG |
2 |
0.2667 |
Tier II |
10 |
NC_000002.12 |
2 |
227260382 |
+ |
COL4A3 |
NNNCTACATATTGAAAACCC |
NGG |
2 |
0.2294 |
Tier II |
11 |
NC_000001.11 |
1 |
34909473 |
- |
DLGAP3 |
NNNATACCTATTGAAATCCT |
NGG |
2 |
0.04 |
Tier II |
12 |
NC_000017.11 |
17 |
30135036 |
- |
NSRP1 |
NNNATACCCATTGAAAACCC |
NTG |
2 |
0.036 |
Tier II |
13 |
NC_000001.11 |
1 |
202426338 |
- |
PPP1R12B |
NNNATACCTATTAAAAACCC |
NGC |
2 |
0.0205 |
Tier II |
14 |
NC_000016.10 |
16 |
53172550 |
- |
CHD9 |
NNNATACCTATTAAAAACCC |
NGC |
2 |
0.0205 |
Tier II |
15 |
NC_000018.10 |
18 |
9344732 |
+ |
TWSG1 |
NNNATACCTATTGAAAACCA |
NTG |
2 |
0.0195 |
Tier II |
16 |
NC_000005.10 |
5 |
176393490 |
+ |
CLTB |
NNNATACCTATGGAAAACCC |
NGC |
2 |
0.0111 |
Tier II |
17 |
NC_000005.10 |
5 |
176393490 |
+ |
ARL10 |
NNNATACCTATGGAAAACCC |
NGC |
2 |
0.0111 |
Tier II |
18 |
NC_000005.10 |
5 |
148129335 |
+ |
SPINK5 |
NNNATACCTATTGAAAACAC |
NGC |
2 |
0.0095 |
Tier II |
19 |
NC_000004.12 |
4 |
84886691 |
- |
WDFY3 |
NNNATACCTATTGAAAAACC |
NGT |
2 |
0.0087 |
Tier II |
20 |
NC_000012.12 |
12 |
89496772 |
- |
POC1B |
NNNATCCCTATTGAAAACCC |
NGT |
2 |
0.0073 |
Tier II |
21 |
NC_000011.10 |
11 |
12842304 |
+ |
TEAD1 |
NNNATACCTATTGAAAACCC |
NTA |
2 |
0.0 |
Tier II |
22 |
NC_000007.14 |
7 |
100242193 |
- |
CASTOR3P |
NNNAGACCCATTGAAAACCC |
NGG |
2 |
0.5908 |
Tier III |
23 |
NC_000017.11 |
17 |
73786788 |
+ |
LINC00469 |
NNNATACATAATGAAAACCC |
NGG |
2 |
0.4875 |
Tier III |
24 |
NC_000002.12 |
2 |
144933723 |
- |
TEX41 |
NNNATACATATTGTAAACCC |
NGG |
2 |
0.3467 |
Tier III |
25 |
NC_000001.11 |
1 |
221065785 |
- |
LOC101929750 |
NNNAGACCTATTGAAAACAC |
NGG |
2 |
0.2743 |
Tier III |
26 |
NC_000002.12 |
2 |
227260382 |
+ |
MFF-DT |
NNNCTACATATTGAAAACCC |
NGG |
2 |
0.2294 |
Tier III |
27 |
NC_000008.11 |
8 |
25669499 |
+ |
LOC107986933 |
NNNATACCTATTGAACACCC |
NGG |
1 |
0.0 |
Tier III |
Gene matches for this target sequence (CRISPRko, PAM=NGG, mouse):
| Reference Sequence |
Chromosome |
Cut Position |
Match Strand |
Match Gene |
Match Sequence |
PAM Seq. |
Mismatches[?]Genomic matches are found by querying with a reduced sequence corresponding to the final 17mer of the 20mer guide target sequence, combined with the `GG` of the PAM sequence. Mismatches are assessed within this set of bases only, for a total of 19 possible matching bases. |
CFD Score[?]Off target matches are assesed via a Cutting Frequency Determination, or CFD score. This value provides an estimate of how specific mismatches affect the likelihood that an sgRNA will cut a given target sequence. For more information, see Doench, Fusi et al., Nature Biotechnology 2016. |
Match Tier[?]For a description of CRISPR match tiers, see How the sgRNA Designer Works. |
1 |
NC_000072.6 |
6 |
113523366 |
- |
Emc3 |
NNNATAACTTTTGAAAACCC |
NGG |
2 |
0.6618 |
Tier II |
2 |
NC_000082.6 |
16 |
37801647 |
+ |
Fstl1 |
NNNCTACCTATTAAAAACCC |
NGG |
2 |
0.3258 |
Tier II |
3 |
NC_000075.6 |
9 |
88807335 |
- |
Gm10634 |
NNNATACCTAGAGAAAACCC |
NGG |
2 |
0.32 |
Tier II |
4 |
NC_000075.6 |
9 |
88876397 |
+ |
Gm2396 |
NNNATACCTAGAGAAAACCC |
NGG |
2 |
0.32 |
Tier II |
5 |
NC_000067.6 |
1 |
188690012 |
- |
Ush2a |
NNNATACCTCATGAAAACCC |
NGG |
2 |
0.25 |
Tier II |
6 |
NC_000069.6 |
3 |
89776905 |
+ |
Ube2q1 |
NNNATAGCTATTGGAAACCC |
NGG |
2 |
0.2196 |
Tier II |
7 |
NC_000072.6 |
6 |
40447181 |
- |
Wee2 |
NNNATACCTAGTGAAAACTC |
NGG |
2 |
0.1846 |
Tier II |
8 |
NC_000077.6 |
11 |
95072642 |
- |
Itga3 |
NNNATACCTACTGAAAAGCC |
NGG |
2 |
0.0889 |
Tier II |
9 |
NC_000075.6 |
9 |
88619337 |
+ |
Gm26567 |
NNNATACCTAGAGAAAACCC |
NGG |
2 |
0.32 |
Tier III |
10 |
NC_000075.6 |
9 |
88619337 |
+ |
Gm29415 |
NNNATACCTAGAGAAAACCC |
NGG |
2 |
0.32 |
Tier III |
11 |
NC_000075.6 |
9 |
88876397 |
+ |
Gm26611 |
NNNATACCTAGAGAAAACCC |
NGG |
2 |
0.32 |
Tier III |
12 |
NC_000075.6 |
9 |
89123154 |
+ |
4930579C12Rik |
NNNATACCTAGAGAAAACCC |
NGG |
2 |
0.32 |
Tier III |
Other clones with same target sequence:
(none)