Transcript: Human NM_001130823.3

Homo sapiens DNA methyltransferase 1 (DNMT1), transcript variant 1, mRNA.

Source:
NCBI, updated 2019-09-10
Taxon:
Homo sapiens (human)
Gene:
DNMT1 (1786)
Length:
5274
CDS:
55..4953

Additional Resources:

NCBI RefSeq record:
NM_001130823.3
NBCI Gene record:
DNMT1 (1786)

sgRNA constructs matching this transcript (CRISPRko, NGG PAM)

This list includes CRISPRko constructs with 100% (20mer + NGG) sequence match to the coding regions of this transcript.

No results found.

shRNA constructs matching this transcript with 100% SDR[?] match

This list includes all shRNAs that have a perfect SDR[?] match to Human NM_001130823.3, regardless of what transcript they were originally designed to target. For example, this list can include shRNAs that were originally designed to target: (i) a different isoform or obsolete version of this transcript (as annotated by NCBI), (ii) a transcript of an orthologous gene (in this collection, generally human-to-mouse or mouse-to-human), or (iii) a transcript of a different gene (from the same or different taxon).

Clone ID Target Seq Vector Match Position Match Region[?] SDR Match %[?] Intrinsic Score[?] Adjusted Score[?] Matches Other Human Gene?[?] Orig. Target Gene[?] Addgene[?]
1 TRCN0000232748 CCCGAGTATGCGCCCATATTT pLKO_005 1579 CDS 100% 15.000 21.000 N DNMT1 n/a
2 TRCN0000232751 GAGGTTCGCTTATCAACTAAT pLKO_005 5094 3UTR 100% 13.200 18.480 N DNMT1 n/a
3 TRCN0000232750 ACCGAATTGGCCGGATCAAAG pLKO_005 3074 CDS 100% 10.800 15.120 N DNMT1 n/a
4 TRCN0000021892 CGAGAAGAATATCGAACTCTT pLKO.1 1383 CDS 100% 4.950 6.930 N DNMT1 n/a
5 TRCN0000021891 GCCCAATGAGACTGACATCAA pLKO.1 3126 CDS 100% 4.950 6.930 N DNMT1 n/a
6 TRCN0000021890 GCCGAATACATTCTGATGGAT pLKO.1 1552 CDS 100% 3.000 4.200 N DNMT1 n/a
7 TRCN0000364177 GACGACCCTGACCTCAAATAT pLKO_005 1183 CDS 100% 15.000 10.500 N DNMT1 n/a
8 TRCN0000232749 CGATGAGGAAGTCGATGATAA pLKO_005 2205 CDS 100% 13.200 9.240 N DNMT1 n/a
9 TRCN0000232747 TTGAATCTCTTGCACGAATTT pLKO_005 190 CDS 100% 13.200 9.240 N DNMT1 n/a
10 TRCN0000364187 ATCAAATTGTGCAGTACTTTG pLKO_005 5124 3UTR 100% 10.800 7.560 N DNMT1 n/a
11 TRCN0000364186 GATCAAGACTACGCGAGATTC pLKO_005 2710 CDS 100% 10.800 7.560 N DNMT1 n/a
12 TRCN0000021893 CGACTACATCAAAGGCAGCAA pLKO.1 3033 CDS 100% 2.640 1.848 N DNMT1 n/a
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shRNA constructs with at least a near match to this transcript

This list includes shRNAs that have at least a >84% (16 of 19 bases) SDR[?] match to the transcript NM_001130823.3, regardless of what transcript they were originally designed to target. For example, this list can include shRNAs that were originally designed to target: (i) a different isoform or obsolete version of this transcript (as annotated by NCBI), (ii) a transcript of an orthologous gene (in this collection, generally human-to-mouse or mouse-to-human), or (iii) a transcript of a different gene (from the same or different taxon). NOTE: this download is a superset of the above result set.

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All ORF constructs matching this transcript

No results found.