Construct: sgRNA BRDN0001145097
Construct Description:
- Construct Type:
- sgRNA
- Other Identifiers:
- n/a
- DNA Barcode:
- AGAGGGTCATCACACACAAG
Original Target:
- Taxon:
-
Homo sapiens (human)
- Gene:
- CD2 (914)
- Gene Description:
- n/a
- CRISPR Mechanism
- CRISPRko
Vector Information:
- Vector Backbone:
- pXPR_003
- Pol II Cassette 1:
- EF1A-PuroR
- Pol II Cassette 2:
- n/a
- Selection Marker:
- PuroR
- Visible Reporter:
- n/a
- Epitope Tag:
- n/a
Additional Information:
- Addgene ID:
- 75825
Gene matches for this target sequence (CRISPRko, PAM=NGG, human):
| Reference Sequence |
Chromosome |
Cut Position |
Match Strand |
Match Gene |
Match Sequence |
PAM Seq. |
Mismatches[?]Genomic matches are found by querying with a reduced sequence corresponding to the final 17mer of the 20mer guide target sequence, combined with the `GG` of the PAM sequence. Mismatches are assessed within this set of bases only, for a total of 19 possible matching bases. |
CFD Score[?]Off target matches are assesed via a Cutting Frequency Determination, or CFD score. This value provides an estimate of how specific mismatches affect the likelihood that an sgRNA will cut a given target sequence. For more information, see Doench, Fusi et al., Nature Biotechnology 2016. |
Match Tier[?]For a description of CRISPR match tiers, see How the sgRNA Designer Works. |
1 |
NC_000001.11 |
1 |
116760542 |
+ |
CD2 |
NNNGGGTCATCACACACAAG |
NGG |
0 |
1.0 |
Tier I |
2 |
NC_000016.10 |
16 |
1210404 |
+ |
CACNA1H |
NNNAGGTCATCACACACAAG |
NTG |
2 |
0.0351 |
Tier I |
3 |
NC_000017.11 |
17 |
32538937 |
+ |
MYO1D |
NNNGGAACATCACACACAAG |
NGG |
2 |
0.875 |
Tier II |
4 |
NC_000003.12 |
3 |
29696865 |
+ |
RBMS3 |
NNNGAGTCATCATACACAAG |
NGG |
2 |
0.6067 |
Tier II |
5 |
NC_000002.12 |
2 |
171146374 |
+ |
TLK1 |
NNNGGGTGCTCACACACAAG |
NGG |
2 |
0.3673 |
Tier II |
6 |
NC_000011.10 |
11 |
61949878 |
+ |
BEST1 |
NNNGGGTCACCACACACAGG |
NGG |
2 |
0.2 |
Tier II |
7 |
NC_000017.11 |
17 |
66860413 |
+ |
CACNG5 |
NNNGGTTCATCACACACAAG |
NGA |
2 |
0.0463 |
Tier II |
8 |
NC_000002.12 |
2 |
72431823 |
- |
EXOC6B |
NNNGGGTCATCACACACCAG |
NGC |
2 |
0.0042 |
Tier II |
9 |
NC_000023.11 |
X |
50583433 |
- |
SHROOM4 |
NNNGGGCCATCACACTCAAG |
NGG |
2 |
0.0 |
Tier II |
10 |
NC_000002.12 |
2 |
171146374 |
+ |
LOC124906168 |
NNNGGGTGCTCACACACAAG |
NGG |
2 |
0.3673 |
Tier III |
11 |
NC_000004.12 |
4 |
71643691 |
- |
LOC105377271 |
NNNGGGTCATAACACACAAC |
NGG |
2 |
0.3214 |
Tier III |
12 |
NC_000001.11 |
1 |
238399808 |
+ |
LOC105373220 |
NNNGGGTCATCAAACACAAG |
NGA |
2 |
0.0267 |
Tier III |
13 |
NC_000007.14 |
7 |
136109080 |
- |
LOC105375523 |
NNNGGGTCATCACACACCAG |
NGC |
2 |
0.0042 |
Tier III |
Gene matches for this target sequence (CRISPRko, PAM=NGG, mouse):
| Reference Sequence |
Chromosome |
Cut Position |
Match Strand |
Match Gene |
Match Sequence |
PAM Seq. |
Mismatches[?]Genomic matches are found by querying with a reduced sequence corresponding to the final 17mer of the 20mer guide target sequence, combined with the `GG` of the PAM sequence. Mismatches are assessed within this set of bases only, for a total of 19 possible matching bases. |
CFD Score[?]Off target matches are assesed via a Cutting Frequency Determination, or CFD score. This value provides an estimate of how specific mismatches affect the likelihood that an sgRNA will cut a given target sequence. For more information, see Doench, Fusi et al., Nature Biotechnology 2016. |
Match Tier[?]For a description of CRISPR match tiers, see How the sgRNA Designer Works. |
1 |
NC_000077.6 |
11 |
58702264 |
- |
Olfr319 |
NNNGTGTCTTCACACACAAG |
NGG |
2 |
0.18 |
Tier I |
2 |
NC_000079.6 |
13 |
81459820 |
+ |
Adgrv1 |
NNNGGGTCATCAGACAAAAG |
NGG |
2 |
0.0636 |
Tier I |
3 |
NC_000073.6 |
7 |
43784891 |
- |
Klk10 |
NNNGTGTCATCACACACCAG |
NGG |
2 |
0.0571 |
Tier I |
4 |
NC_000075.6 |
9 |
64948265 |
- |
Slc24a1 |
NNNGAGTCATCACACACAAG |
NTG |
2 |
0.0338 |
Tier I |
5 |
NC_000071.6 |
5 |
32341865 |
- |
Plb1 |
NNNGGGTCATCACTCACATG |
NGG |
2 |
0.2872 |
Tier II |
6 |
NC_000077.6 |
11 |
121077813 |
+ |
Sectm1a |
NNNGTGTCATCACACACAAA |
NGG |
2 |
0.2813 |
Tier II |
7 |
NC_000070.6 |
4 |
152179018 |
+ |
Acot7 |
NNNGGGTCATCTCACACAAT |
NGG |
2 |
0.2333 |
Tier II |
8 |
NC_000075.6 |
9 |
88770128 |
- |
Gm10634 |
NNNGTGTCATAACACACAAG |
NGG |
2 |
0.225 |
Tier II |
9 |
NC_000075.6 |
9 |
88918184 |
+ |
Gm2396 |
NNNGTGTCATAACACACAAG |
NGG |
2 |
0.225 |
Tier II |
10 |
NC_000074.6 |
8 |
122330823 |
+ |
Zfpm1 |
NNNTGGGCATCACACACAAG |
NGG |
2 |
0.2139 |
Tier II |
11 |
NC_000077.6 |
11 |
82435286 |
+ |
Tmem132e |
NNNGGGTCATCTCACAAAAG |
NGG |
2 |
0.1556 |
Tier II |
12 |
NC_000081.6 |
15 |
83141919 |
+ |
Poldip3 |
NNNGGGTCGTCACAAACAAG |
NGG |
2 |
0.1481 |
Tier II |
13 |
NC_000083.6 |
17 |
26428684 |
- |
Neurl1b |
NNNGGGTCAGCACACACAAG |
NAG |
2 |
0.1296 |
Tier II |
14 |
NC_000075.6 |
9 |
49397374 |
- |
Drd2 |
NNNGGGTCCTCACAAACAAG |
NGG |
2 |
0.127 |
Tier II |
15 |
NC_000067.6 |
1 |
64927906 |
+ |
Plekhm3 |
NNNAGGTCATCAGACACAAG |
NGG |
2 |
0.1227 |
Tier II |
16 |
NC_000067.6 |
1 |
78547875 |
+ |
Mogat1 |
NNNGGGTCATCACCCACAGG |
NGG |
2 |
0.0804 |
Tier II |
17 |
NC_000073.6 |
7 |
50828021 |
+ |
Nell1 |
NNNGAGTCATCACACACAAG |
NGA |
2 |
0.0602 |
Tier II |
18 |
NC_000068.7 |
2 |
15806677 |
+ |
Malrd1 |
NNNGGGTTATCACACAGAAG |
NGG |
2 |
0.0515 |
Tier II |
19 |
NC_000076.6 |
10 |
73327815 |
+ |
Pcdh15 |
NNNGGGTCACCACACACAAG |
NTG |
2 |
0.0208 |
Tier II |
20 |
NC_000085.6 |
19 |
42748225 |
+ |
Pyroxd2 |
NNNGGGTCATCACCCACAAG |
NTG |
2 |
0.0083 |
Tier II |
21 |
NC_000071.6 |
5 |
32341865 |
- |
Gm36840 |
NNNGGGTCATCACTCACATG |
NGG |
2 |
0.2872 |
Tier III |
22 |
NC_000071.6 |
5 |
147747658 |
- |
Gm35541 |
NNNGTGTCATCATACACAAG |
NGG |
2 |
0.21 |
Tier III |
23 |
NC_000068.7 |
2 |
144466412 |
+ |
Gm38402 |
NNNGGCTCATCAGACACAAG |
NGG |
2 |
0.093 |
Tier III |
24 |
NC_000068.7 |
2 |
144466412 |
+ |
Zfp133-ps |
NNNGGCTCATCAGACACAAG |
NGG |
2 |
0.093 |
Tier III |
25 |
NC_000080.6 |
14 |
22015189 |
- |
Gm41106 |
NNNGGGTCAGCACACACAAG |
NGC |
2 |
0.0111 |
Tier III |
26 |
NC_000085.6 |
19 |
42748225 |
+ |
Gm19437 |
NNNGGGTCATCACCCACAAG |
NTG |
2 |
0.0083 |
Tier III |
Other clones with same target sequence:
(none)