Construct: sgRNA BRDN0001145419
Construct Description:
- Construct Type:
- sgRNA
- Other Identifiers:
- n/a
- DNA Barcode:
- CTAGTTGGTGAGGATAGCCA
Original Target:
- Taxon:
-
Homo sapiens (human)
- Gene:
- CSNK2A1 (1457)
- Gene Description:
- n/a
- CRISPR Mechanism
- CRISPRko
Vector Information:
- Vector Backbone:
- pXPR_003
- Pol II Cassette 1:
- EF1A-PuroR
- Pol II Cassette 2:
- n/a
- Selection Marker:
- PuroR
- Visible Reporter:
- n/a
- Epitope Tag:
- n/a
Additional Information:
- Addgene ID:
- 76673
Gene matches for this target sequence (CRISPRko, PAM=NGG, human):
| Reference Sequence |
Chromosome |
Cut Position |
Match Strand |
Match Gene |
Match Sequence |
PAM Seq. |
Mismatches[?]Genomic matches are found by querying with a reduced sequence corresponding to the final 17mer of the 20mer guide target sequence, combined with the `GG` of the PAM sequence. Mismatches are assessed within this set of bases only, for a total of 19 possible matching bases. |
CFD Score[?]Off target matches are assesed via a Cutting Frequency Determination, or CFD score. This value provides an estimate of how specific mismatches affect the likelihood that an sgRNA will cut a given target sequence. For more information, see Doench, Fusi et al., Nature Biotechnology 2016. |
Match Tier[?]For a description of CRISPR match tiers, see How the sgRNA Designer Works. |
1 |
NC_000020.11 |
20 |
488766 |
- |
CSNK2A1 |
NNNGTTGGTGAGGATAGCCA |
NGG |
0 |
1.0 |
Tier I |
2 |
NC_000016.10 |
16 |
89198819 |
+ |
SLC22A31 |
NNNGTTGGTGAGGATGCCCA |
NGG |
2 |
0.0452 |
Tier I |
3 |
NC_000011.10 |
11 |
11352384 |
- |
CSNK2A3 |
NNNGTTGGTGAGGATAGCCA |
NGT |
1 |
0.0161 |
Tier I |
4 |
NC_000020.11 |
20 |
8238192 |
+ |
PLCB1 |
NNNGTTGGTGGGAATAGCCA |
NGG |
2 |
0.6 |
Tier II |
5 |
NC_000013.11 |
13 |
99206489 |
- |
UBAC2 |
NNNGCTGGTGAGCATAGCCA |
NGG |
2 |
0.4211 |
Tier II |
6 |
NC_000012.12 |
12 |
1416481 |
- |
ERC1 |
NNNGTGGGTGGGGATAGCCA |
NGG |
2 |
0.3714 |
Tier II |
7 |
NC_000010.11 |
10 |
75603897 |
+ |
LRMDA |
NNNGTTGATGAGGACAGCCA |
NGG |
2 |
0.2727 |
Tier II |
8 |
NC_000007.14 |
7 |
123971025 |
- |
SPAM1 |
NNNGTTGGTGATGATAGTCA |
NGG |
2 |
0.2473 |
Tier II |
9 |
NC_000003.12 |
3 |
123955347 |
- |
CCDC14 |
NNNGGTGGTGAGTATAGCCA |
NGG |
2 |
0.192 |
Tier II |
10 |
NC_000006.12 |
6 |
52421864 |
+ |
EFHC1 |
NNNGTTGGTGAGTATAGACA |
NGG |
2 |
0.1615 |
Tier II |
11 |
NC_000003.12 |
3 |
46901994 |
- |
PTH1R |
NNNGTGGGTGAGGACAGCCA |
NGG |
2 |
0.1558 |
Tier II |
12 |
NC_000002.12 |
2 |
3200850 |
+ |
EIPR1 |
NNNCTTGGTGAGGACAGCCA |
NGG |
2 |
0.1444 |
Tier II |
13 |
NC_000019.10 |
19 |
44867719 |
+ |
NECTIN2 |
NNNGCTGGTGAGGATAGGCA |
NGG |
2 |
0.1333 |
Tier II |
14 |
NC_000015.10 |
15 |
28948910 |
+ |
APBA2 |
NNNGTTGGTGAGGATAGGCA |
NGG |
1 |
0.1333 |
Tier II |
15 |
NC_000020.11 |
20 |
32195343 |
- |
PLAGL2 |
NNNGTTGGTGTGGATAGCAA |
NGG |
2 |
0.1319 |
Tier II |
16 |
NC_000003.12 |
3 |
131851606 |
+ |
CPNE4 |
NNNGTTGGTGATGATAGCGA |
NGG |
2 |
0.0481 |
Tier II |
17 |
NC_000011.10 |
11 |
11352384 |
- |
GALNT18 |
NNNGTTGGTGAGGATAGCCA |
NGT |
1 |
0.0161 |
Tier II |
18 |
NC_000001.11 |
1 |
151513894 |
+ |
CGN |
NNNGTTGGTGAGGAGAGCCC |
NGG |
2 |
0.0114 |
Tier II |
19 |
NC_000012.12 |
12 |
7860426 |
+ |
SLC2A14 |
NNNGTTGGTCAGGATAGCCA |
NGC |
2 |
0.0089 |
Tier II |
20 |
NC_000012.12 |
12 |
56082817 |
+ |
ERBB3 |
NNNGTGGGTGAGGATTGCCA |
NGG |
2 |
0.0 |
Tier II |
21 |
NC_000016.10 |
16 |
20855663 |
- |
DCUN1D3 |
NNNGTTGGTGAGGATCGGCA |
NGG |
2 |
0.0 |
Tier II |
22 |
NC_000014.9 |
14 |
29118385 |
+ |
LOC107984685 |
NNNGTTAGTGAGGATAGCCA |
NAG |
2 |
0.2593 |
Tier III |
23 |
NC_000007.14 |
7 |
141516199 |
- |
AGK-DT |
NNNGTTGGGGAGGACAGCCA |
NGG |
2 |
0.1688 |
Tier III |
24 |
NC_000015.10 |
15 |
39513911 |
+ |
LOC105370784 |
NNNGTTGATGAGGATAGCCA |
NGA |
2 |
0.0694 |
Tier III |
25 |
NC_000003.12 |
3 |
88282718 |
+ |
LOC105377202 |
NNNGTTGGTGAGGATAGGAA |
NGG |
2 |
0.0571 |
Tier III |
26 |
NC_000003.12 |
3 |
131851606 |
+ |
LOC105374113 |
NNNGTTGGTGATGATAGCGA |
NGG |
2 |
0.0481 |
Tier III |
Gene matches for this target sequence (CRISPRko, PAM=NGG, mouse):
| Reference Sequence |
Chromosome |
Cut Position |
Match Strand |
Match Gene |
Match Sequence |
PAM Seq. |
Mismatches[?]Genomic matches are found by querying with a reduced sequence corresponding to the final 17mer of the 20mer guide target sequence, combined with the `GG` of the PAM sequence. Mismatches are assessed within this set of bases only, for a total of 19 possible matching bases. |
CFD Score[?]Off target matches are assesed via a Cutting Frequency Determination, or CFD score. This value provides an estimate of how specific mismatches affect the likelihood that an sgRNA will cut a given target sequence. For more information, see Doench, Fusi et al., Nature Biotechnology 2016. |
Match Tier[?]For a description of CRISPR match tiers, see How the sgRNA Designer Works. |
1 |
NC_000068.7 |
2 |
152274106 |
+ |
Csnk2a1 |
NNNGTTGGTGAGGATAGCCA |
NGG |
0 |
1.0 |
Tier I |
2 |
NC_000068.7 |
2 |
66090950 |
- |
Galnt3 |
NNNGTTGGTGAGAATAACCA |
NGG |
2 |
0.8615 |
Tier I |
3 |
NC_000073.6 |
7 |
127786036 |
- |
Setd1a |
NNNGGTGGGGAGGATAGCCA |
NGG |
2 |
0.3962 |
Tier I |
4 |
NC_000077.6 |
11 |
120110972 |
- |
Slc38a10 |
NNNGTTGCTGAGGATAGCCA |
NGA |
2 |
0.0427 |
Tier I |
5 |
NC_000076.6 |
10 |
64345451 |
+ |
Ctnna3 |
NNNGTTGCTGAAGATAGCCA |
NGG |
2 |
0.5744 |
Tier II |
6 |
NC_000079.6 |
13 |
94263178 |
- |
Scamp1 |
NNNGTTGGTGAAGTTAGCCA |
NGG |
2 |
0.4978 |
Tier II |
7 |
NC_000079.6 |
13 |
109506819 |
+ |
Pde4d |
NNNGTTGGTGAGGAAAGCCG |
NGG |
2 |
0.4427 |
Tier II |
8 |
NC_000080.6 |
14 |
32677706 |
+ |
3425401B19Rik |
NNNGTTGGTGGGGATAGCCT |
NGG |
2 |
0.39 |
Tier II |
9 |
NC_000078.6 |
12 |
116428866 |
+ |
Ncapg2 |
NNNGTTGGTGAGGATAGACT |
NGG |
2 |
0.3231 |
Tier II |
10 |
NC_000077.6 |
11 |
69757323 |
- |
Polr2a |
NNNGTGGGTGAGGATAGACA |
NGG |
2 |
0.3077 |
Tier II |
11 |
NC_000076.6 |
10 |
76004064 |
+ |
Gm5134 |
NNNCTTGGTGAGGTTAGCCA |
NGG |
2 |
0.2824 |
Tier II |
12 |
NC_000077.6 |
11 |
106166239 |
- |
Strada |
NNNCTTGGTCAGGATAGCCA |
NGG |
2 |
0.2118 |
Tier II |
13 |
NC_000079.6 |
13 |
54626337 |
+ |
Faf2 |
NNNCTTGGTCAGGATAGCCA |
NGG |
2 |
0.2118 |
Tier II |
14 |
NC_000068.7 |
2 |
27478564 |
- |
Brd3 |
NNNGTTGGTGGGGACAGCCA |
NGG |
2 |
0.1773 |
Tier II |
15 |
NC_000068.7 |
2 |
26059122 |
+ |
Nacc2 |
NNNGGTGGTGAGGACAGCCA |
NGG |
2 |
0.1745 |
Tier II |
16 |
NC_000075.6 |
9 |
45104341 |
+ |
Jaml |
NNNGTTGGGGAGGATACCCA |
NGG |
2 |
0.1457 |
Tier II |
17 |
NC_000072.6 |
6 |
146728352 |
- |
Stk38l |
NNNGTTGGTAAGGATAGGCA |
NGG |
2 |
0.1244 |
Tier II |
18 |
NC_000075.6 |
9 |
36861400 |
+ |
Fez1 |
NNNGTTGGTGATGATAGCCA |
NAG |
2 |
0.0997 |
Tier II |
19 |
NC_000068.7 |
2 |
15910495 |
- |
Malrd1 |
NNNGTTGGTGATGATAGCCC |
NGG |
2 |
0.0874 |
Tier II |
20 |
NC_000073.6 |
7 |
142474684 |
- |
Lsp1 |
NNNGTTGGTGATGCTAGCCA |
NGG |
2 |
0.0824 |
Tier II |
21 |
NC_000073.6 |
7 |
100920621 |
- |
Arhgef17 |
NNNGTTGGTGAGGAAAGGCA |
NGG |
2 |
0.0772 |
Tier II |
22 |
NC_000073.6 |
7 |
16578637 |
- |
Arhgap35 |
NNNGTTGGTAAGGATAGCCA |
NGT |
2 |
0.0151 |
Tier II |
23 |
NC_000068.7 |
2 |
31101534 |
+ |
Fnbp1 |
NNNGTTGGTGAGGAGAGCCC |
NGG |
2 |
0.0114 |
Tier II |
24 |
NC_000067.6 |
1 |
156524967 |
+ |
Csnk2a3 |
NNNGTTGGTGAGGATAGCCA |
NGG |
0 |
1.0 |
Tier III |
25 |
NC_000070.6 |
4 |
75325238 |
+ |
Gm11255 |
NNNGTTGGTGAGGATAGCCA |
NGG |
0 |
1.0 |
Tier III |
26 |
NC_000084.6 |
18 |
81448057 |
+ |
Gm30288 |
NNNGTTGATGAGGATAGCCT |
NGG |
2 |
0.6 |
Tier III |
27 |
NC_000086.7 |
X |
16610992 |
+ |
Csnk2a1-ps |
NNNGTTGGTGAGGAAAGCCA |
NGG |
1 |
0.5789 |
Tier III |
28 |
NC_000074.6 |
8 |
83952164 |
+ |
Gm10644 |
NNNGGTGGTGAGGTTAGCCA |
NGG |
2 |
0.3413 |
Tier III |
29 |
NC_000078.6 |
12 |
113806964 |
- |
Igh |
NNNGTAGGTGAGGACAGCCA |
NGG |
2 |
0.2364 |
Tier III |
30 |
NC_000083.6 |
17 |
40854628 |
- |
Gm20574 |
NNNGTTGGTGTGGATAGCCC |
NGG |
2 |
0.0699 |
Tier III |
31 |
NC_000080.6 |
14 |
14198032 |
+ |
Csnk2a1-ps1 |
NNNGTTGGTGAGGAGAGCCA |
NGG |
1 |
0.05 |
Tier III |
32 |
NC_000074.6 |
8 |
24385413 |
- |
Gm30633 |
NNNGTTGGTGAGGATGGGCA |
NGG |
2 |
0.0256 |
Tier III |
Other clones with same target sequence:
(none)