Construct: sgRNA BRDN0001145821
Construct Description:
- Construct Type:
- sgRNA
- Other Identifiers:
- n/a
- DNA Barcode:
- AGGCTGACACATTAAAGGAG
Original Target:
- Taxon:
-
Homo sapiens (human)
- Gene:
- CSNK1G3 (1456)
- Gene Description:
- n/a
- CRISPR Mechanism
- CRISPRko
Vector Information:
- Vector Backbone:
- pXPR_003
- Pol II Cassette 1:
- EF1A-PuroR
- Pol II Cassette 2:
- n/a
- Selection Marker:
- PuroR
- Visible Reporter:
- n/a
- Epitope Tag:
- n/a
Additional Information:
- Addgene ID:
- 77361
Gene matches for this target sequence (CRISPRko, PAM=NGG, human):
| Reference Sequence |
Chromosome |
Cut Position |
Match Strand |
Match Gene |
Match Sequence |
PAM Seq. |
Mismatches[?]Genomic matches are found by querying with a reduced sequence corresponding to the final 17mer of the 20mer guide target sequence, combined with the `GG` of the PAM sequence. Mismatches are assessed within this set of bases only, for a total of 19 possible matching bases. |
CFD Score[?]Off target matches are assesed via a Cutting Frequency Determination, or CFD score. This value provides an estimate of how specific mismatches affect the likelihood that an sgRNA will cut a given target sequence. For more information, see Doench, Fusi et al., Nature Biotechnology 2016. |
Match Tier[?]For a description of CRISPR match tiers, see How the sgRNA Designer Works. |
1 |
NC_000005.10 |
5 |
123588442 |
+ |
CSNK1G3 |
NNNCTGACACATTAAAGGAG |
NGG |
0 |
1.0 |
Tier I |
2 |
NC_000015.10 |
15 |
64204935 |
- |
CSNK1G1 |
NNNCTGACACATTAAAAGAG |
NGA |
2 |
0.0648 |
Tier I |
3 |
NC_000003.12 |
3 |
4092467 |
- |
SUMF1 |
NNNCTGACACATTAAAATAG |
NGG |
2 |
0.6222 |
Tier II |
4 |
NC_000001.11 |
1 |
156976059 |
+ |
ARHGEF11 |
NNNCTAACTCATTAAAGGAG |
NGG |
2 |
0.6 |
Tier II |
5 |
NC_000001.11 |
1 |
240452332 |
- |
FMN2 |
NNNCTGACTAATTAAAGGAG |
NGG |
2 |
0.52 |
Tier II |
6 |
NC_000013.11 |
13 |
39454836 |
+ |
LHFPL6 |
NNNCTGATACATTTAAGGAG |
NGG |
2 |
0.4667 |
Tier II |
7 |
NC_000003.12 |
3 |
123802418 |
+ |
MYLK |
NNNAAGACACATTAAAGGAG |
NGG |
2 |
0.4211 |
Tier II |
8 |
NC_000008.11 |
8 |
3397890 |
- |
CSMD1 |
NNNCTGACACCTTAAAGGAT |
NGG |
2 |
0.28 |
Tier II |
9 |
NC_000018.10 |
18 |
36773239 |
+ |
FHOD3 |
NNNCTGACACATTAAAGAGG |
NGG |
2 |
0.2596 |
Tier II |
10 |
NC_000023.11 |
X |
31403206 |
- |
DMD |
NNNCTGACACATTACAAGAG |
NGG |
2 |
0.2545 |
Tier II |
11 |
NC_000020.11 |
20 |
6080215 |
+ |
FERMT1 |
NNNCTGACACAGTGAAGGAG |
NGG |
2 |
0.2333 |
Tier II |
12 |
NC_000009.12 |
9 |
114906166 |
- |
TNFSF8 |
NNNCTGACACATTATAGGAA |
NGG |
2 |
0.1875 |
Tier II |
13 |
NC_000006.12 |
6 |
43361244 |
- |
ZNF318 |
NNNCTGACAGATTGAAGGAG |
NGG |
2 |
0.1815 |
Tier II |
14 |
NC_000003.12 |
3 |
138593975 |
+ |
CEP70 |
NNNCTGAGACATTAAAGGAG |
NAG |
2 |
0.1667 |
Tier II |
15 |
NC_000016.10 |
16 |
27873981 |
- |
GSG1L |
NNNTTGACACATTAAGGGAG |
NGG |
2 |
0.1538 |
Tier II |
16 |
NC_000002.12 |
2 |
214326085 |
- |
SPAG16 |
NNNCTGACACATTATAGGAT |
NGG |
2 |
0.14 |
Tier II |
17 |
NC_000011.10 |
11 |
92311845 |
- |
FAT3 |
NNNCTGACACATTAAACCAG |
NGG |
2 |
0.112 |
Tier II |
18 |
NC_000008.11 |
8 |
120547656 |
+ |
SNTB1 |
NNNCTGACACATTAAATGAC |
NGG |
2 |
0.1071 |
Tier II |
19 |
NC_000022.11 |
22 |
33637500 |
- |
LARGE1 |
NNNCTGACACAGTATAGGAG |
NGG |
2 |
0.1 |
Tier II |
20 |
NC_000004.12 |
4 |
72344818 |
+ |
ADAMTS3 |
NNNCTGACACTTTAAAGGAG |
NGT |
2 |
0.005 |
Tier II |
21 |
NC_000023.11 |
X |
128331583 |
- |
LOC107985698 |
NNNCTCACACATTAAAAGAG |
NGG |
2 |
0.6364 |
Tier III |
22 |
NC_000009.12 |
9 |
21535950 |
- |
MIR31HG |
NNNCTGACAGATAAAAGGAG |
NGG |
2 |
0.2692 |
Tier III |
23 |
NC_000014.9 |
14 |
95334652 |
- |
LINC02292 |
NNNGTGACACCTTAAAGGAG |
NGG |
2 |
0.2 |
Tier III |
24 |
NC_000014.9 |
14 |
95334652 |
- |
LOC124903371 |
NNNGTGACACCTTAAAGGAG |
NGG |
2 |
0.2 |
Tier III |
Gene matches for this target sequence (CRISPRko, PAM=NGG, mouse):
| Reference Sequence |
Chromosome |
Cut Position |
Match Strand |
Match Gene |
Match Sequence |
PAM Seq. |
Mismatches[?]Genomic matches are found by querying with a reduced sequence corresponding to the final 17mer of the 20mer guide target sequence, combined with the `GG` of the PAM sequence. Mismatches are assessed within this set of bases only, for a total of 19 possible matching bases. |
CFD Score[?]Off target matches are assesed via a Cutting Frequency Determination, or CFD score. This value provides an estimate of how specific mismatches affect the likelihood that an sgRNA will cut a given target sequence. For more information, see Doench, Fusi et al., Nature Biotechnology 2016. |
Match Tier[?]For a description of CRISPR match tiers, see How the sgRNA Designer Works. |
1 |
NC_000084.6 |
18 |
53930293 |
+ |
Csnk1g3 |
NNNCTGACACATTAAAAGAG |
NGG |
1 |
0.9333 |
Tier I |
2 |
NC_000069.6 |
3 |
136872942 |
- |
Ppp3ca |
NNNCTGGCACATTAAAGGAA |
NGG |
2 |
0.6618 |
Tier II |
3 |
NC_000074.6 |
8 |
77176975 |
- |
Nr3c2 |
NNNCTGACGCATTAAAAGAG |
NGG |
2 |
0.6222 |
Tier II |
4 |
NC_000078.6 |
12 |
71313537 |
- |
Dact1 |
NNNCTGACACATCAAAGAAG |
NGG |
2 |
0.5466 |
Tier II |
5 |
NC_000071.6 |
5 |
150581957 |
+ |
N4bp2l1 |
NNNTTGAAACATTAAAGGAG |
NGG |
2 |
0.52 |
Tier II |
6 |
NC_000071.6 |
5 |
131614073 |
+ |
Auts2 |
NNNCTGAAACATCAAAGGAG |
NGG |
2 |
0.5132 |
Tier II |
7 |
NC_000073.6 |
7 |
3430310 |
- |
Cacng6 |
NNNCTGACACATAAGAGGAG |
NGG |
2 |
0.45 |
Tier II |
8 |
NC_000080.6 |
14 |
59523476 |
- |
Cab39l |
NNNCTGACAGATTAAAGGAA |
NGG |
2 |
0.3646 |
Tier II |
9 |
NC_000069.6 |
3 |
58687176 |
+ |
Siah2 |
NNNCTGACACTTTAAAGGAG |
NGG |
1 |
0.3077 |
Tier II |
10 |
NC_000067.6 |
1 |
73933305 |
- |
Tns1 |
NNNCTGACTCAGTAAAGGAG |
NGG |
2 |
0.3 |
Tier II |
11 |
NC_000067.6 |
1 |
58062955 |
- |
Aox1 |
NNNCTGACTCATTAAAGCAG |
NGG |
2 |
0.2857 |
Tier II |
12 |
NC_000071.6 |
5 |
98388175 |
- |
Cfap299 |
NNNCTGACACATCACAGGAG |
NGG |
2 |
0.2153 |
Tier II |
13 |
NC_000085.6 |
19 |
15979180 |
+ |
Cep78 |
NNNCTGTCACATTAAAGGAC |
NGG |
2 |
0.1875 |
Tier II |
14 |
NC_000083.6 |
17 |
13133109 |
- |
Unc93a |
NNNCTGGCACATGAAAGGAG |
NGG |
2 |
0.1841 |
Tier II |
15 |
NC_000070.6 |
4 |
84453693 |
+ |
Bnc2 |
NNNCTGTCACTTTAAAGGAG |
NGG |
2 |
0.1346 |
Tier II |
16 |
NC_000079.6 |
13 |
81254873 |
+ |
Adgrv1 |
NNNCTGACACATAAAGGGAG |
NGG |
2 |
0.1331 |
Tier II |
17 |
NC_000074.6 |
8 |
70112357 |
+ |
Ncan |
NNNCTGACACTTTCAAGGAG |
NGG |
2 |
0.0659 |
Tier II |
18 |
NC_000082.6 |
16 |
41773394 |
+ |
Lsamp |
NNNCTGACACATTAAAGAAG |
NTG |
2 |
0.027 |
Tier II |
19 |
NC_000068.7 |
2 |
40940893 |
+ |
Lrp1b |
NNNCTGACACATTAAAGGAG |
NAA |
2 |
0.0 |
Tier II |
20 |
NC_000083.6 |
17 |
49812022 |
+ |
Kif6 |
NNNCTGACACATTAAAGGAG |
NTT |
2 |
0.0 |
Tier II |
21 |
NC_000086.7 |
X |
53418781 |
+ |
Gm14584 |
NNNCTGACACATTAAAAGAG |
NGG |
1 |
0.9333 |
Tier III |
22 |
NC_000076.6 |
10 |
99634827 |
- |
Gm20110 |
NNNCTGACACATCAAAAGAG |
NGG |
2 |
0.7368 |
Tier III |
23 |
NC_000068.7 |
2 |
172976302 |
+ |
Gm52538 |
NNNCTGACTCACTAAAGGAG |
NGG |
2 |
0.5684 |
Tier III |
24 |
NC_000070.6 |
4 |
24887946 |
- |
Gm46848 |
NNNGTGACACATCAAAGGAG |
NGG |
2 |
0.3947 |
Tier III |
25 |
NC_000070.6 |
4 |
24893096 |
- |
Gm46848 |
NNNGTGACACATCAAAGGAG |
NGG |
2 |
0.3947 |
Tier III |
26 |
NC_000082.6 |
16 |
93628930 |
+ |
Gm5678 |
NNNCTTCCACATTAAAGGAG |
NGG |
2 |
0.2917 |
Tier III |
27 |
NC_000083.6 |
17 |
13133109 |
- |
Gm36277 |
NNNCTGGCACATGAAAGGAG |
NGG |
2 |
0.1841 |
Tier III |
28 |
NC_000079.6 |
13 |
9032366 |
- |
Gm36264 |
NNNCTGACACATGCAAGGAG |
NGG |
2 |
0.0559 |
Tier III |
29 |
NC_000079.6 |
13 |
44024857 |
+ |
Gm33489 |
NNNCTGACACATTAAAGGAG |
NTA |
2 |
0.0 |
Tier III |
Other clones with same target sequence:
(none)