Construct: sgRNA BRDN0001146689
Construct Description:
- Construct Type:
- sgRNA
- Other Identifiers:
- n/a
- DNA Barcode:
- GAAGTGCAAACACTTGCTTG
Original Target:
- Taxon:
-
Homo sapiens (human)
- Gene:
- PRKD3 (23683)
- Gene Description:
- n/a
- CRISPR Mechanism
- CRISPRko
Vector Information:
- Vector Backbone:
- pXPR_003
- Pol II Cassette 1:
- EF1A-PuroR
- Pol II Cassette 2:
- n/a
- Selection Marker:
- PuroR
- Visible Reporter:
- n/a
- Epitope Tag:
- n/a
Additional Information:
- Addgene ID:
- 75951
Gene matches for this target sequence (CRISPRko, PAM=NGG, human):
Gene matches for this target sequence (CRISPRko, PAM=NGG, mouse):
| Reference Sequence |
Chromosome |
Cut Position |
Match Strand |
Match Gene |
Match Sequence |
PAM Seq. |
Mismatches[?]Genomic matches are found by querying with a reduced sequence corresponding to the final 17mer of the 20mer guide target sequence, combined with the `GG` of the PAM sequence. Mismatches are assessed within this set of bases only, for a total of 19 possible matching bases. |
CFD Score[?]Off target matches are assesed via a Cutting Frequency Determination, or CFD score. This value provides an estimate of how specific mismatches affect the likelihood that an sgRNA will cut a given target sequence. For more information, see Doench, Fusi et al., Nature Biotechnology 2016. |
Match Tier[?]For a description of CRISPR match tiers, see How the sgRNA Designer Works. |
1 |
NC_000083.6 |
17 |
78966215 |
+ |
Prkd3 |
NNNGTGCAAACACTTGCTTG |
NGG |
0 |
1.0 |
Tier I |
2 |
NC_000076.6 |
10 |
73649090 |
- |
Pcdh15 |
NNNGTATAAACACTTGCTTG |
NGG |
2 |
0.8125 |
Tier II |
3 |
NC_000072.6 |
6 |
90904952 |
- |
Iqsec1 |
NNNGTGTACACACTTGCTTG |
NGG |
2 |
0.4643 |
Tier II |
4 |
NC_000070.6 |
4 |
48069412 |
+ |
Nr4a3 |
NNNGTGCAGACACTAGCTTG |
NGG |
2 |
0.386 |
Tier II |
5 |
NC_000071.6 |
5 |
21209866 |
- |
Gsap |
NNNGTTCAAACACTTGTTTG |
NGG |
2 |
0.3111 |
Tier II |
6 |
NC_000072.6 |
6 |
121454093 |
+ |
Iqsec3 |
NNNGTGCAAACACTTGCTTA |
NAG |
2 |
0.2431 |
Tier II |
7 |
NC_000076.6 |
10 |
13327965 |
+ |
Phactr2 |
NNNTGGCAAACACTTGCTTG |
NGG |
2 |
0.2327 |
Tier II |
8 |
NC_000074.6 |
8 |
12633146 |
- |
Tubgcp3 |
NNNGAGCCAACACTTGCTTG |
NGG |
2 |
0.2143 |
Tier II |
9 |
NC_000077.6 |
11 |
63069530 |
- |
Tekt3 |
NNNGTGCAAACACATGCGTG |
NGG |
2 |
0.2063 |
Tier II |
10 |
NC_000071.6 |
5 |
148241609 |
- |
Mtus2 |
NNNTAGCAAACACTTGCTTG |
NGG |
2 |
0.1818 |
Tier II |
11 |
NC_000071.6 |
5 |
45574837 |
+ |
Fam184b |
NNNGTGCAAAGACTTGCATG |
NGG |
2 |
0.1667 |
Tier II |
12 |
NC_000074.6 |
8 |
119717676 |
+ |
Atp2c2 |
NNNGTGCTAACTCTTGCTTG |
NGG |
2 |
0.1429 |
Tier II |
13 |
NC_000085.6 |
19 |
10098122 |
+ |
Fads2 |
NNNGTGCAAACACTGGCTTG |
NGG |
1 |
0.05 |
Tier II |
14 |
NC_000073.6 |
7 |
38224851 |
+ |
Plekhf1 |
NNNATGCAAACACTTGCTTG |
NGC |
2 |
0.02 |
Tier II |
15 |
NC_000072.6 |
6 |
106454628 |
- |
Cntn4 |
NNNGTGCAAACACTTGCATG |
NGT |
2 |
0.0108 |
Tier II |
16 |
NC_000068.7 |
2 |
148686976 |
- |
Gzf1 |
NNNATGCAAACACTTCCTTG |
NGG |
2 |
0.0 |
Tier II |
17 |
NC_000085.6 |
19 |
32624783 |
+ |
Papss2 |
NNNGTGCAAACACTTTTTTG |
NGG |
2 |
0.0 |
Tier II |
18 |
NC_000074.6 |
8 |
23869289 |
+ |
Zmat4 |
NNNGTGCAAACATGTGCTTG |
NGG |
2 |
0.0 |
Tier II |
19 |
NC_000080.6 |
14 |
25146449 |
- |
Gm32224 |
NNNGTGCATACACTTGCTTT |
NGG |
2 |
0.42 |
Tier III |
20 |
NC_000068.7 |
2 |
71602813 |
- |
Gm36857 |
NNNGTGGAAACACTTGCCTG |
NGG |
2 |
0.2017 |
Tier III |
Other clones with same target sequence:
(none)