Construct: sgRNA BRDN0001147566
Construct Description:
- Construct Type:
- sgRNA
- Other Identifiers:
- n/a
- DNA Barcode:
- TCCCACCATAAGAACCCCAG
Original Target:
- Taxon:
- Homo sapiens (human)
- Gene:
- CSNK1G1 (53944)
- Gene Description:
- n/a
- CRISPR Mechanism
- CRISPRko
Gene matches for this target sequence (CRISPRko, PAM=NGG, human):
Reference Sequence | Chromosome | Cut Position | Match Strand | Match Gene | Match Sequence | PAM Seq. | Mismatches[?]Genomic matches are found by querying with a reduced sequence corresponding to the final 17mer of the 20mer guide target sequence, combined with the `GG` of the PAM sequence. Mismatches are assessed within this set of bases only, for a total of 19 possible matching bases. | CFD Score[?]Off target matches are assesed via a Cutting Frequency Determination, or CFD score. This value provides an estimate of how specific mismatches affect the likelihood that an sgRNA will cut a given target sequence. For more information, see Doench, Fusi et al., Nature Biotechnology 2016. | Match Tier[?]For a description of CRISPR match tiers, see How the sgRNA Designer Works. | |
---|---|---|---|---|---|---|---|---|---|---|
1 | NC_000015.10 | 15 | 64300394 | + | CSNK1G1 | NNNCACCATAAGAACCCCAG | NGG | 0 | 1.0 | Tier I |
2 | NC_000017.11 | 17 | 74930724 | + | OTOP2 | NNNCACCATAAGAACCCCAC | NCG | 2 | 0.0459 | Tier I |
3 | NC_000017.11 | 17 | 7292686 | + | YBX2 | NNNTATCATAAGAACCCCAG | NGG | 2 | 0.7429 | Tier II |
4 | NC_000004.12 | 4 | 53110290 | + | SCFD2 | NNNCACCATAAAAACCCTAG | NGG | 2 | 0.6 | Tier II |
5 | NC_000017.11 | 17 | 50102767 | - | PDK2 | NNNCTCCACAAGAACCCCAG | NGG | 2 | 0.3357 | Tier II |
6 | NC_000001.11 | 1 | 44270735 | + | ERI3 | NNNCACTATAAGAACTCCAG | NGG | 2 | 0.25 | Tier II |
7 | NC_000017.11 | 17 | 79590196 | + | RBFOX3 | NNNCAGGATAAGAACCCCAG | NGG | 2 | 0.2353 | Tier II |
8 | NC_000010.11 | 10 | 87544388 | - | MINPP1 | NNNCTCCATAAGAACCCAAG | NGG | 2 | 0.1958 | Tier II |
9 | NC_000017.11 | 17 | 3692472 | - | P2RX5 | NNNCACCATCACAACCCCAG | NGG | 2 | 0.1765 | Tier II |
10 | NC_000002.12 | 2 | 182202640 | + | PDE1A | NNNCATCATAAGAACCCCAG | NGA | 2 | 0.0645 | Tier II |
11 | NC_000019.10 | 19 | 45342936 | - | KLC3 | NNNCACCATAAGCAGCCCAG | NGG | 2 | 0.0105 | Tier II |
12 | NC_000019.10 | 19 | 47438192 | - | SLC8A2 | NNNCACCATACGAACCCCAG | NGC | 2 | 0.0089 | Tier II |
13 | NC_000001.11 | 1 | 204456488 | + | PIK3C2B | NNNCACCATAAGAATCCCAG | NGA | 2 | 0.0046 | Tier II |
14 | NC_000006.12 | 6 | 74437525 | - | LOC101928516 | NNNCACCATAAAAACCCTAG | NGG | 2 | 0.6 | Tier III |
15 | NC_000017.11 | 17 | 3692472 | - | P2RX5-TAX1BP3 | NNNCACCATCACAACCCCAG | NGG | 2 | 0.1765 | Tier III |
16 | NC_000015.10 | 15 | 66935381 | - | SMASR | NNNCACTATAAGAAGCCCAG | NGG | 2 | 0.0406 | Tier III |
17 | NC_000019.10 | 19 | 31839132 | + | LINC01837 | NNNCACCATATGAATCCCAG | NGG | 2 | 0.0205 | Tier III |
Gene matches for this target sequence (CRISPRko, PAM=NGG, mouse):
Reference Sequence | Chromosome | Cut Position | Match Strand | Match Gene | Match Sequence | PAM Seq. | Mismatches[?]Genomic matches are found by querying with a reduced sequence corresponding to the final 17mer of the 20mer guide target sequence, combined with the `GG` of the PAM sequence. Mismatches are assessed within this set of bases only, for a total of 19 possible matching bases. | CFD Score[?]Off target matches are assesed via a Cutting Frequency Determination, or CFD score. This value provides an estimate of how specific mismatches affect the likelihood that an sgRNA will cut a given target sequence. For more information, see Doench, Fusi et al., Nature Biotechnology 2016. | Match Tier[?]For a description of CRISPR match tiers, see How the sgRNA Designer Works. | |
---|---|---|---|---|---|---|---|---|---|---|
1 | NC_000075.6 | 9 | 65958647 | - | Csnk1g1 | NNNCACCATGAGAACCCCAG | NGG | 1 | 0.5556 | Tier I |
2 | NC_000083.6 | 17 | 78224952 | - | Crim1 | NNNCACCATTAGAACCCCAG | NGG | 1 | 0.8824 | Tier II |
3 | NC_000080.6 | 14 | 4047348 | + | Gm32966 | NNNCACCATAACAACCCCAG | NGG | 1 | 0.5294 | Tier II |
4 | NC_000080.6 | 14 | 4139157 | + | Gm32966 | NNNCACCATAACAACCCCAG | NGG | 1 | 0.5294 | Tier II |
5 | NC_000080.6 | 14 | 4676973 | + | Gm3239 | NNNCACCATAACAACCCCAG | NGG | 1 | 0.5294 | Tier II |
6 | NC_000080.6 | 14 | 4753588 | + | Gm26650 | NNNCACCATAACAACCCCAG | NGG | 1 | 0.5294 | Tier II |
7 | NC_000080.6 | 14 | 4790784 | + | Gm26650 | NNNCACCATAACAACCCCAG | NGG | 1 | 0.5294 | Tier II |
8 | NC_000080.6 | 14 | 4882995 | + | Gm26650 | NNNCACCATAACAACCCCAG | NGG | 1 | 0.5294 | Tier II |
9 | NC_000080.6 | 14 | 5432088 | - | Gm3194 | NNNCACCATAACAACCCCAG | NGG | 1 | 0.5294 | Tier II |
10 | NC_000080.6 | 14 | 5933181 | - | Gm3248 | NNNCACCATAACAACCCCAG | NGG | 1 | 0.5294 | Tier II |
11 | NC_000080.6 | 14 | 6011531 | - | LOC115488283 | NNNCACCATAACAACCCCAG | NGG | 1 | 0.5294 | Tier II |
12 | NC_000080.6 | 14 | 6522841 | - | LOC108168187 | NNNCACCATAACAACCCCAG | NGG | 1 | 0.5294 | Tier II |
13 | NC_000080.6 | 14 | 7077219 | - | Gm3696 | NNNCACCATAACAACCCCAG | NGG | 1 | 0.5294 | Tier II |
14 | NC_000080.6 | 14 | 7077219 | - | Gm31035 | NNNCACCATAACAACCCCAG | NGG | 1 | 0.5294 | Tier II |
15 | NC_000085.6 | 19 | 31054496 | + | Prkg1 | NNNCACCATAAGAGCACCAG | NGG | 2 | 0.4667 | Tier II |
16 | NC_000074.6 | 8 | 27089320 | + | Adgra2 | NNNCACCAGAAGGACCCCAG | NGG | 2 | 0.4037 | Tier II |
17 | NC_000079.6 | 13 | 19092086 | - | Amph | NNNAACCATAAGAACCACAG | NGG | 2 | 0.393 | Tier II |
18 | NC_000073.6 | 7 | 44078529 | - | Klk1b21 | NNNCCCCATAAGAACCCCAT | NGG | 2 | 0.35 | Tier II |
19 | NC_000078.6 | 12 | 24584800 | - | Grhl1 | NNNCAGCATAAGGACCCCAG | NGG | 2 | 0.3261 | Tier II |
20 | NC_000075.6 | 9 | 22436551 | + | 9530077C05Rik | NNNCATCATCAGAACCCCAG | NGG | 2 | 0.3095 | Tier II |
21 | NC_000068.7 | 2 | 7360657 | - | Celf2 | NNNCATCATAAGAAACCCAG | NGG | 2 | 0.2063 | Tier II |
22 | NC_000083.6 | 17 | 6018946 | - | Synj2 | NNNCACCATAGGAACTCCAG | NGG | 2 | 0.2 | Tier II |
23 | NC_000076.6 | 10 | 77835029 | + | Tspear | NNNCACCATCAGAACCACAG | NGG | 2 | 0.1556 | Tier II |
24 | NC_000075.6 | 9 | 31454626 | + | Tmem45b | NNNCACCATGAGCACCCCAG | NGG | 2 | 0.117 | Tier II |
25 | NC_000085.6 | 19 | 37587163 | + | Exoc6 | NNNCACCCTAAGAACCCCCG | NGG | 2 | 0.0887 | Tier II |
26 | NC_000084.6 | 18 | 6628019 | - | 4921524L21Rik | NNNCACCATCAGCACCCCAG | NGG | 2 | 0.0702 | Tier II |
27 | NC_000076.6 | 10 | 70181365 | - | Ccdc6 | NNNCACCATAAGAACACCAG | NTG | 2 | 0.039 | Tier II |
28 | NC_000080.6 | 14 | 122131491 | - | Tm9sf2 | NNNCACCATAAGAAGCCCAT | NGG | 2 | 0.035 | Tier II |
29 | NC_000082.6 | 16 | 63760833 | - | Epha3 | NNNCACCATATGAACCCCAG | NGA | 2 | 0.0214 | Tier II |
30 | NC_000068.7 | 2 | 68266868 | - | Stk39 | NNNCACCATATGAATCCCAG | NGG | 2 | 0.0205 | Tier II |
31 | NC_000080.6 | 14 | 4449433 | + | Gm3164 | NNNCACCATAACAACCCCAG | NGG | 1 | 0.5294 | Tier III |
32 | NC_000080.6 | 14 | 5176392 | + | Gm26552 | NNNCACCATAACAACCCCAG | NGG | 1 | 0.5294 | Tier III |
33 | NC_000080.6 | 14 | 5359812 | - | Gm41087 | NNNCACCATAACAACCCCAG | NGG | 1 | 0.5294 | Tier III |
34 | NC_000080.6 | 14 | 5712354 | - | Gm36476 | NNNCACCATAACAACCCCAG | NGG | 1 | 0.5294 | Tier III |
35 | NC_000080.6 | 14 | 5933181 | - | Gm51421 | NNNCACCATAACAACCCCAG | NGG | 1 | 0.5294 | Tier III |
36 | NC_000080.6 | 14 | 6011531 | - | Gm51421 | NNNCACCATAACAACCCCAG | NGG | 1 | 0.5294 | Tier III |
37 | NC_000080.6 | 14 | 6399734 | - | Gm26630 | NNNCACCATAACAACCCCAG | NGG | 1 | 0.5294 | Tier III |
38 | NC_000080.6 | 14 | 6729628 | - | Gm26680 | NNNCACCATAACAACCCCAG | NGG | 1 | 0.5294 | Tier III |
39 | NC_000080.6 | 14 | 6862393 | - | Gm32041 | NNNCACCATAACAACCCCAG | NGG | 1 | 0.5294 | Tier III |
40 | NC_000080.6 | 14 | 6959425 | - | Gm32041 | NNNCACCATAACAACCCCAG | NGG | 1 | 0.5294 | Tier III |
41 | NC_000074.6 | 8 | 27089320 | + | Gm39151 | NNNCACCAGAAGGACCCCAG | NGG | 2 | 0.4037 | Tier III |
42 | NC_000080.6 | 14 | 6826246 | - | Gm26680 | NNNCACCCTAACAACCCCAG | NGG | 2 | 0.2269 | Tier III |
43 | NC_000079.6 | 13 | 78577183 | + | Gm32067 | NNNCACCATAAGAACCACAG | NAG | 2 | 0.121 | Tier III |
44 | NC_000081.6 | 15 | 8742509 | + | Gm31340 | NNNCACCATAAGACCCTCAG | NGG | 2 | 0.1 | Tier III |