Construct: sgRNA BRDN0001487130
Construct Description:
- Construct Type:
- sgRNA
- Other Identifiers:
- n/a
- DNA Barcode:
- CCAGTTGCTCTGGGGGAACA
Original Target:
- Taxon:
-
Homo sapiens (human)
- Gene:
- NO_SITE control
- CRISPR Mechanism
- CRISPRko
Vector Information:
- Vector Backbone:
- pXPR_003
- Pol II Cassette 1:
- EF1A-PuroR
- Pol II Cassette 2:
- n/a
- Selection Marker:
- PuroR
- Visible Reporter:
- n/a
- Epitope Tag:
- n/a
Additional Information:
- Addgene ID:
- 80262
Gene matches for this target sequence (CRISPRko, PAM=NGG, human):
Gene matches for this target sequence (CRISPRko, PAM=NGG, mouse):
| Reference Sequence |
Chromosome |
Cut Position |
Match Strand |
Match Gene |
Match Sequence |
PAM Seq. |
Mismatches[?]Genomic matches are found by querying with a reduced sequence corresponding to the final 17mer of the 20mer guide target sequence, combined with the `GG` of the PAM sequence. Mismatches are assessed within this set of bases only, for a total of 19 possible matching bases. |
CFD Score[?]Off target matches are assesed via a Cutting Frequency Determination, or CFD score. This value provides an estimate of how specific mismatches affect the likelihood that an sgRNA will cut a given target sequence. For more information, see Doench, Fusi et al., Nature Biotechnology 2016. |
Match Tier[?]For a description of CRISPR match tiers, see How the sgRNA Designer Works. |
1 |
NC_000084.6 |
18 |
24660026 |
- |
Mocos |
NNNCTGGCTCTGGGGGAACA |
NGG |
2 |
0.3025 |
Tier I |
2 |
NC_000075.6 |
9 |
59603532 |
- |
Celf6 |
NNNGTTGCTCTGGGGGGTCA |
NGG |
2 |
0.0882 |
Tier I |
3 |
NC_000071.6 |
5 |
51819811 |
- |
Ppargc1a |
NNNGTTGCCCAGGGGGAACA |
NGG |
2 |
0.6923 |
Tier II |
4 |
NC_000075.6 |
9 |
63954776 |
- |
Smad6 |
NNNGTTCTTCTGGGGGAACA |
NGG |
2 |
0.6016 |
Tier II |
5 |
NC_000085.6 |
19 |
46041842 |
- |
Ldb1 |
NNNGCTGCTCTGGGGGAACT |
NGG |
2 |
0.6 |
Tier II |
6 |
NC_000075.6 |
9 |
42454032 |
- |
Tbcel |
NNNGGTCCTCTGGGGGAACA |
NGG |
2 |
0.44 |
Tier II |
7 |
NC_000078.6 |
12 |
28809409 |
- |
Eipr1 |
NNNGTTTCTCTGGAGGAACA |
NGG |
2 |
0.4286 |
Tier II |
8 |
NC_000075.6 |
9 |
86829038 |
- |
Snap91 |
NNNATTGCTCTGGGGGAGCA |
NGG |
2 |
0.36 |
Tier II |
9 |
NC_000078.6 |
12 |
66984003 |
- |
Mdga2 |
NNNTTTGCTCTGGGAGAACA |
NGG |
2 |
0.3422 |
Tier II |
10 |
NC_000071.6 |
5 |
140037858 |
- |
Mad1l1 |
NNNCTTGCTCTGGGGGATCA |
NGG |
2 |
0.2647 |
Tier II |
11 |
NC_000083.6 |
17 |
47904226 |
+ |
Foxp4 |
NNNGCTGCTCTGGGGGAACA |
NAG |
2 |
0.2593 |
Tier II |
12 |
NC_000077.6 |
11 |
97832534 |
+ |
Lasp1 |
NNNTTTCCTCTGGGGGAACA |
NGG |
2 |
0.25 |
Tier II |
13 |
NC_000071.6 |
5 |
113776286 |
+ |
Iscu |
NNNCTTGCTCTGGGGGAAAA |
NGG |
2 |
0.2269 |
Tier II |
14 |
NC_000068.7 |
2 |
132061167 |
- |
Slc23a2 |
NNNGTTGCTCTGAGGGAACC |
NGG |
2 |
0.2098 |
Tier II |
15 |
NC_000077.6 |
11 |
70012698 |
+ |
Acadvl |
NNNGTTGCTGTGGGGGAAAA |
NGG |
2 |
0.1667 |
Tier II |
16 |
NC_000082.6 |
16 |
59495262 |
- |
Crybg3 |
NNNGATGCTCTGGGGGAACA |
NAG |
2 |
0.1296 |
Tier II |
17 |
NC_000070.6 |
4 |
19922311 |
- |
Atp6v0d2 |
NNNGTTGCTCTGGGGAAAGA |
NGG |
2 |
0.125 |
Tier II |
18 |
NC_000077.6 |
11 |
69617966 |
+ |
Shbg |
NNNGTTGCTCTGGGGGAAGA |
NGG |
1 |
0.125 |
Tier II |
19 |
NC_000079.6 |
13 |
91051742 |
+ |
Atg10 |
NNNTTTGCTCTGGTGGAACA |
NGG |
2 |
0.097 |
Tier II |
20 |
NC_000068.7 |
2 |
143793998 |
- |
Pcsk2 |
NNNGTTGCTCTGGAGGAAGA |
NGG |
2 |
0.0938 |
Tier II |
21 |
NC_000070.6 |
4 |
47402435 |
- |
Tgfbr1 |
NNNGTTGCTCTGGAGGAAGA |
NGG |
2 |
0.0938 |
Tier II |
22 |
NC_000068.7 |
2 |
152756491 |
- |
Cox4i2 |
NNNGTTCCTCTGGGGGAAGA |
NGG |
2 |
0.0859 |
Tier II |
23 |
NC_000074.6 |
8 |
47350165 |
- |
Stox2 |
NNNGTTTCTCTGGGTGAACA |
NGG |
2 |
0.0816 |
Tier II |
24 |
NC_000078.6 |
12 |
100428330 |
+ |
Ttc7b |
NNNGGTGCTCTGGGGGAAGA |
NGG |
2 |
0.08 |
Tier II |
25 |
NC_000077.6 |
11 |
5967540 |
+ |
Ykt6 |
NNNGTTGCTCTGGGGGTACT |
NGG |
2 |
0.08 |
Tier II |
26 |
NC_000082.6 |
16 |
37795208 |
+ |
Fstl1 |
NNNGCTGCTCTGGGGGAACA |
NTG |
2 |
0.039 |
Tier II |
27 |
NC_000075.6 |
9 |
69385231 |
- |
Rora |
NNNGTTGTTCTGGGGGAACA |
NTG |
2 |
0.0341 |
Tier II |
28 |
NC_000078.6 |
12 |
102969962 |
- |
Unc79 |
NNNGTTGCTTTGGGGGAACA |
NGT |
2 |
0.0152 |
Tier II |
29 |
NC_000071.6 |
5 |
140802408 |
- |
Gna12 |
NNNGTTGCTCTGGGGTAAAA |
NGG |
2 |
0.0 |
Tier II |
30 |
NC_000067.6 |
1 |
180933273 |
+ |
Gm39715 |
NNNGATGCTCTGGGAGAACA |
NGG |
2 |
0.4706 |
Tier III |
31 |
NC_000075.6 |
9 |
86998352 |
+ |
Gm36539 |
NNNGTTGCTCTGGGAGATCA |
NGG |
2 |
0.4706 |
Tier III |
32 |
NC_000085.6 |
19 |
30352761 |
+ |
Gm36006 |
NNNGTGGATCTGGGGGAACA |
NGG |
2 |
0.3714 |
Tier III |
33 |
NC_000078.6 |
12 |
15049026 |
- |
4930448C13Rik |
NNNGTTGCTCTGGAGGGACA |
NGG |
2 |
0.1324 |
Tier III |
34 |
NC_000076.6 |
10 |
3512182 |
- |
Gm30033 |
NNNGTTCCTCTGGGGGTACA |
NGG |
2 |
0.0917 |
Tier III |
35 |
NC_000068.7 |
2 |
152756491 |
- |
Gm32057 |
NNNGTTCCTCTGGGGGAAGA |
NGG |
2 |
0.0859 |
Tier III |
Other clones with same target sequence:
(none)