Construct: sgRNA BRDN0001145662
Construct Description:
- Construct Type:
- sgRNA
- Other Identifiers:
- n/a
- DNA Barcode:
- CGAAGTCTTTCTTAGATGGT
Original Target:
- Taxon:
-
Homo sapiens (human)
- Gene:
- NO_SITE control
- CRISPR Mechanism
- CRISPRko
Vector Information:
- Vector Backbone:
- pXPR_003
- Pol II Cassette 1:
- EF1A-PuroR
- Pol II Cassette 2:
- n/a
- Selection Marker:
- PuroR
- Visible Reporter:
- n/a
- Epitope Tag:
- n/a
Additional Information:
- Addgene ID:
- 80233
Gene matches for this target sequence (CRISPRko, PAM=NGG, human):
| Reference Sequence |
Chromosome |
Cut Position |
Match Strand |
Match Gene |
Match Sequence |
PAM Seq. |
Mismatches[?]Genomic matches are found by querying with a reduced sequence corresponding to the final 17mer of the 20mer guide target sequence, combined with the `GG` of the PAM sequence. Mismatches are assessed within this set of bases only, for a total of 19 possible matching bases. |
CFD Score[?]Off target matches are assesed via a Cutting Frequency Determination, or CFD score. This value provides an estimate of how specific mismatches affect the likelihood that an sgRNA will cut a given target sequence. For more information, see Doench, Fusi et al., Nature Biotechnology 2016. |
Match Tier[?]For a description of CRISPR match tiers, see How the sgRNA Designer Works. |
1 |
NC_000014.9 |
14 |
50916831 |
- |
PYGL |
NNNAGTCTTTCATAGAAGGT |
NGG |
2 |
0.4267 |
Tier II |
2 |
NC_000002.12 |
2 |
154002009 |
+ |
GALNT13 |
NNNAGTCTTTCTTGGAAGGT |
NGG |
2 |
0.2489 |
Tier II |
3 |
NC_000003.12 |
3 |
52730732 |
+ |
NEK4 |
NNNTTTCTTTCTTAGATGGT |
NGG |
2 |
0.1909 |
Tier II |
4 |
NC_000004.12 |
4 |
146423947 |
- |
SLC10A7 |
NNNGGTCTTTCTTACATGGT |
NGG |
2 |
0.1705 |
Tier II |
5 |
NC_000015.10 |
15 |
27235374 |
+ |
GABRG3 |
NNNAGGCTTTCTTAGATGGT |
NAG |
2 |
0.1481 |
Tier II |
6 |
NC_000014.9 |
14 |
37443579 |
- |
MIPOL1 |
NNNTGTCTTTCTTATATGGT |
NGG |
2 |
0.0909 |
Tier II |
7 |
NC_000010.11 |
10 |
119815307 |
+ |
INPP5F |
NNNATTCTTTCTTAGATGGT |
NAG |
2 |
0.0778 |
Tier II |
8 |
NC_000018.10 |
18 |
36894986 |
- |
KIAA1328 |
NNNAGTCTTTCTTAGCTGGT |
NTG |
2 |
0.0 |
Tier II |
9 |
NC_000001.11 |
1 |
15952889 |
- |
ZBTB17 |
NNNAGTCTTTCTTAGTTGGA |
NGG |
2 |
0.0 |
Tier II |
10 |
NC_000018.10 |
18 |
32914582 |
+ |
LOC105372058 |
NNNAGTCATTCTTAAATGGT |
NGG |
2 |
0.7529 |
Tier III |
11 |
NC_000016.10 |
16 |
65529326 |
- |
LINC00922 |
NNNAGTCTGACTTAGATGGT |
NGG |
2 |
0.5306 |
Tier III |
12 |
NC_000004.12 |
4 |
79856241 |
- |
PCAT4 |
NNNAGTCTTTCTTGGATGGT |
NGG |
1 |
0.4667 |
Tier III |
13 |
NC_000007.14 |
7 |
25349641 |
- |
LOC105375195 |
NNNAGTCTTTTTTAGAAGGT |
NGG |
2 |
0.1641 |
Tier III |
14 |
NC_000010.11 |
10 |
119815307 |
+ |
PHACTR2P1 |
NNNATTCTTTCTTAGATGGT |
NAG |
2 |
0.0778 |
Tier III |
15 |
NC_000010.11 |
10 |
119815307 |
+ |
LOC105378513 |
NNNATTCTTTCTTAGATGGT |
NAG |
2 |
0.0778 |
Tier III |
16 |
NC_000011.10 |
11 |
45520885 |
+ |
LOC105376654 |
NNNAGTCTTTCTGAGATGGG |
NGG |
2 |
0.046 |
Tier III |
17 |
NC_000001.11 |
1 |
15952889 |
- |
LOC124903855 |
NNNAGTCTTTCTTAGTTGGA |
NGG |
2 |
0.0 |
Tier III |
Gene matches for this target sequence (CRISPRko, PAM=NGG, mouse):
| Reference Sequence |
Chromosome |
Cut Position |
Match Strand |
Match Gene |
Match Sequence |
PAM Seq. |
Mismatches[?]Genomic matches are found by querying with a reduced sequence corresponding to the final 17mer of the 20mer guide target sequence, combined with the `GG` of the PAM sequence. Mismatches are assessed within this set of bases only, for a total of 19 possible matching bases. |
CFD Score[?]Off target matches are assesed via a Cutting Frequency Determination, or CFD score. This value provides an estimate of how specific mismatches affect the likelihood that an sgRNA will cut a given target sequence. For more information, see Doench, Fusi et al., Nature Biotechnology 2016. |
Match Tier[?]For a description of CRISPR match tiers, see How the sgRNA Designer Works. |
1 |
NC_000076.6 |
10 |
94079168 |
+ |
Fgd6 |
NNNAGTCTTACTTAGATGGT |
NGG |
1 |
0.8571 |
Tier II |
2 |
NC_000069.6 |
3 |
159502355 |
- |
Depdc1a |
NNNAGTCCTTCTTAGATGGA |
NGG |
2 |
0.5625 |
Tier II |
3 |
NC_000076.6 |
10 |
114439617 |
+ |
Trhde |
NNNAGTCCTTCTTAGAAGGT |
NGG |
2 |
0.5333 |
Tier II |
4 |
NC_000084.6 |
18 |
57587704 |
- |
Ccdc192 |
NNNAGTCTTTCTCAGAAGGT |
NGG |
2 |
0.4211 |
Tier II |
5 |
NC_000083.6 |
17 |
86058639 |
- |
Srbd1 |
NNNAGTGTGTCTTAGATGGT |
NGG |
2 |
0.2913 |
Tier II |
6 |
NC_000079.6 |
13 |
108089101 |
- |
Ndufaf2 |
NNNATTCTTTCTTAGAAGGT |
NGG |
2 |
0.16 |
Tier II |
7 |
NC_000068.7 |
2 |
181692549 |
+ |
Rgs19 |
NNNAGGCTTTCTGAGATGGT |
NGG |
2 |
0.1491 |
Tier II |
8 |
NC_000077.6 |
11 |
4944851 |
+ |
Nefh |
NNNATTCTTTCTTAGATGCT |
NGG |
2 |
0.1345 |
Tier II |
9 |
NC_000071.6 |
5 |
98661771 |
- |
Cfap299 |
NNNAGTCTTGCTGAGATGGT |
NGG |
2 |
0.1304 |
Tier II |
10 |
NC_000079.6 |
13 |
100126765 |
+ |
Smn1 |
NNNAGGCTTTCTTAGGTGGT |
NGG |
2 |
0.1099 |
Tier II |
11 |
NC_000079.6 |
13 |
117629562 |
- |
Hcn1 |
NNNAGTCTTTCTTAGAAGGG |
NGG |
2 |
0.0941 |
Tier II |
12 |
NC_000081.6 |
15 |
35462682 |
- |
Vps13b |
NNNAGTCTTTCTTAGAAGGG |
NGG |
2 |
0.0941 |
Tier II |
13 |
NC_000068.7 |
2 |
26471633 |
- |
Notch1 |
NNNATTCTTTCTGAGATGGT |
NGG |
2 |
0.0783 |
Tier II |
14 |
NC_000068.7 |
2 |
69382791 |
- |
Dhrs9 |
NNNAGTCTTTCTTAGATGGT |
NGA |
1 |
0.0694 |
Tier II |
15 |
NC_000076.6 |
10 |
13711842 |
- |
Aig1 |
NNNAGTCTTTCTTCCATGGT |
NGG |
2 |
0.0584 |
Tier II |
16 |
NC_000067.6 |
1 |
68614232 |
- |
Erbb4 |
NNNAGTCTTTCTTAGAAGGC |
NGG |
2 |
0.0485 |
Tier II |
17 |
NC_000086.7 |
X |
113818256 |
- |
Dach2 |
NNNAGTCTTTCTTAGAAGGT |
NGA |
2 |
0.037 |
Tier II |
18 |
NC_000067.6 |
1 |
61890369 |
- |
Pard3b |
NNNAGTCTTTCTTAGATGCT |
NGA |
2 |
0.0311 |
Tier II |
19 |
NC_000069.6 |
3 |
145806442 |
- |
Ddah1 |
NNNAGACTTTCTTAGATGGT |
NGT |
2 |
0.014 |
Tier II |
20 |
NC_000068.7 |
2 |
5416220 |
+ |
Camk1d |
NNNAGCCTTTCTTAGTTGGT |
NGG |
2 |
0.0 |
Tier II |
21 |
NC_000073.6 |
7 |
142545845 |
+ |
Nctc1 |
NNNAGCCTTTCTTTGATGGT |
NGG |
2 |
0.4848 |
Tier III |
22 |
NC_000081.6 |
15 |
96494866 |
- |
Gm41392 |
NNNAGCCTTTCTGAGATGGT |
NGG |
2 |
0.2372 |
Tier III |
23 |
NC_000072.6 |
6 |
114359171 |
+ |
Gm38875 |
NNNAGTCTTTGTTAGACGGT |
NGG |
2 |
0.1765 |
Tier III |
24 |
NC_000068.7 |
2 |
69382791 |
- |
Gm36393 |
NNNAGTCTTTCTTAGATGGT |
NGA |
1 |
0.0694 |
Tier III |
25 |
NC_000068.7 |
2 |
78989294 |
+ |
Gm37004 |
NNNAGTCTGTCTTAGATGGC |
NGG |
2 |
0.0563 |
Tier III |
26 |
NC_000083.6 |
17 |
94814793 |
+ |
Gm1976 |
NNNAGTCTTACTTAGATGGT |
NGC |
2 |
0.019 |
Tier III |
27 |
NC_000085.6 |
19 |
43640971 |
+ |
Gm4311 |
NNNAGTCTTTATTAGCTGGT |
NGG |
2 |
0.0 |
Tier III |
28 |
NC_000085.6 |
19 |
43640971 |
+ |
Gm34922 |
NNNAGTCTTTATTAGCTGGT |
NGG |
2 |
0.0 |
Tier III |
29 |
NC_000080.6 |
14 |
104659855 |
+ |
D130009I18Rik |
NNNAGTCTTTCTTAGTTGCT |
NGG |
2 |
0.0 |
Tier III |
30 |
NC_000071.6 |
5 |
75683070 |
+ |
Gm32558 |
NNNAGTCTTTGTTAGCTGGT |
NGG |
2 |
0.0 |
Tier III |
Other clones with same target sequence:
(none)