Transcript: Human XM_011510375.3

PREDICTED: Homo sapiens ADAM metallopeptidase domain 17 (ADAM17), transcript variant X1, mRNA.

Source:
NCBI, updated 2019-09-08
Taxon:
Homo sapiens (human)
Gene:
ADAM17 (6868)
Length:
4400
CDS:
328..2709

Additional Resources:

NCBI RefSeq record:
XM_011510375.3
NBCI Gene record:
ADAM17 (6868)

sgRNA constructs matching this transcript (CRISPRko, NGG PAM)

This list includes CRISPRko constructs with 100% (20mer + NGG) sequence match to the coding regions of this transcript.

No results found.

shRNA constructs matching this transcript with 100% SDR[?] match

This list includes all shRNAs that have a perfect SDR[?] match to Human XM_011510375.3, regardless of what transcript they were originally designed to target. For example, this list can include shRNAs that were originally designed to target: (i) a different isoform or obsolete version of this transcript (as annotated by NCBI), (ii) a transcript of an orthologous gene (in this collection, generally human-to-mouse or mouse-to-human), or (iii) a transcript of a different gene (from the same or different taxon).

Clone ID Target Seq Vector Match Position Match Region[?] SDR Match %[?] Intrinsic Score[?] Adjusted Score[?] Matches Other Human Gene?[?] Orig. Target Gene[?] Addgene[?]
1 TRCN0000052170 CCCATGAAGAACACGTGTAAA pLKO.1 892 CDS 100% 13.200 18.480 N ADAM17 n/a
2 TRCN0000052172 CCTATGTCGATGCTGAACAAA pLKO.1 2072 CDS 100% 5.625 7.875 N ADAM17 n/a
3 TRCN0000286913 CCTATGTCGATGCTGAACAAA pLKO_005 2072 CDS 100% 5.625 7.875 N ADAM17 n/a
4 TRCN0000087375 TCAAGTCTCCACAAGAGGTAA pLKO.1 1088 CDS 100% 4.950 6.930 N LOC436104 n/a
5 TRCN0000294262 GAAGGTGAATCTAGCTTATTT pLKO_005 2897 3UTR 100% 15.000 10.500 N ADAM17 n/a
6 TRCN0000294261 GTTTGTCCAAAGGCTTATTAT pLKO_005 1324 CDS 100% 15.000 10.500 N ADAM17 n/a
7 TRCN0000087373 GATATGGGAACTCTTGGATTA pLKO.1 1264 CDS 100% 10.800 7.560 N LOC436104 n/a
8 TRCN0000052168 CCAGCAGCATTCGGTAAGAAA pLKO.1 384 CDS 100% 5.625 3.938 N ADAM17 n/a
9 TRCN0000311680 CCAGCAGCATTCGGTAAGAAA pLKO_005 384 CDS 100% 5.625 3.938 N ADAM17 n/a
10 TRCN0000052171 CCTGGTTACAACTCATGAATT pLKO.1 1434 CDS 100% 0.000 0.000 N ADAM17 n/a
11 TRCN0000286912 CCTGGTTACAACTCATGAATT pLKO_005 1434 CDS 100% 0.000 0.000 N ADAM17 n/a
12 TRCN0000052169 GCAGCGTCAGAATCGTGTTAA pLKO.1 2667 CDS 100% 13.200 18.480 N ADAM17 n/a
13 TRCN0000078113 GCCTGTAATCCCAGCACTTTA pLKO.1 3524 3UTR 100% 13.200 6.600 Y LIAS n/a
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shRNA constructs with at least a near match to this transcript

This list includes shRNAs that have at least a >84% (16 of 19 bases) SDR[?] match to the transcript XM_011510375.3, regardless of what transcript they were originally designed to target. For example, this list can include shRNAs that were originally designed to target: (i) a different isoform or obsolete version of this transcript (as annotated by NCBI), (ii) a transcript of an orthologous gene (in this collection, generally human-to-mouse or mouse-to-human), or (iii) a transcript of a different gene (from the same or different taxon). NOTE: this download is a superset of the above result set.

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All ORF constructs matching this transcript

Clone ID DNA Barcode Vector Sequenced %[?] Nuc. Match %[?] Prot. Match %[?] Epitope Tag Match Diffs[?] Addgene[?]
1 ccsbBroadEn_11169 pDONR223 100% 21.6% 20.9% None (many diffs) n/a
2 ccsbBroad304_11169 pLX_304 91.3% 21.6% 20.9% V5 (many diffs) n/a
3 TRCN0000467718 CTCCGACATGGTCATCACCCGGCA pLX_317 68.4% 21.6% 20.9% V5 (many diffs) n/a
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