Transcript: Human XM_017008581.2

PREDICTED: Homo sapiens TXK tyrosine kinase (TXK), transcript variant X3, mRNA.

Source:
NCBI, updated 2019-09-08
Taxon:
Homo sapiens (human)
Gene:
TXK (7294)
Length:
6814
CDS:
1173..2681

Additional Resources:

NCBI RefSeq record:
XM_017008581.2
NBCI Gene record:
TXK (7294)

shRNA constructs matching this transcript with 100% SDR[?] match

This list includes all shRNAs that have a perfect SDR[?] match to Human XM_017008581.2, regardless of what transcript they were originally designed to target. For example, this list can include shRNAs that were originally designed to target: (i) a different isoform or obsolete version of this transcript (as annotated by NCBI), (ii) a transcript of an orthologous gene (in this collection, generally human-to-mouse or mouse-to-human), or (iii) a transcript of a different gene (from the same or different taxon).

Clone ID Target Seq Vector Match Position Match Region[?] SDR Match %[?] Intrinsic Score[?] Adjusted Score[?] Matches Other Human Gene?[?] Orig. Target Gene[?] Addgene[?]
1 TRCN0000121108 CCTACACAATTTCCGTATTTA pLKO.1 1645 CDS 100% 15.000 21.000 N TXK n/a
2 TRCN0000121181 GAGTCTAAAGAAGGTGCATTT pLKO.1 1596 CDS 100% 10.800 15.120 N TXK n/a
3 TRCN0000121180 GCACCAATGTCCATATATGAA pLKO.1 2568 CDS 100% 5.625 7.875 N TXK n/a
4 TRCN0000195084 CAAGGAATTGTTTGGTCAGTT pLKO.1 2275 CDS 100% 4.950 6.930 N TXK n/a
5 TRCN0000009998 CCGTATTTATGGGAGCTAGAA pLKO.1 1657 CDS 100% 4.950 6.930 N TXK n/a
6 TRCN0000055429 CCGTATTTATGGGAGCTAGAA pLKO.1 1657 CDS 100% 4.950 6.930 N TXK n/a
7 TRCN0000121111 CCTTTACATTGTGACAGAGTT pLKO.1 2111 CDS 100% 4.950 6.930 N TXK n/a
8 TRCN0000009999 GACACGCCTTTCAATCAATCC pLKO.1 1750 CDS 100% 4.050 5.670 N TXK n/a
9 TRCN0000196957 GCAAGTCGTGGAAGCTATTTC pLKO.1 2516 CDS 100% 13.200 10.560 N TXK n/a
10 TRCN0000121110 GCCCAGAGAACCCTGTAATTT pLKO.1 1379 CDS 100% 15.000 10.500 N TXK n/a
11 TRCN0000196460 GCTCAGCCAATTGTCAAATAA pLKO.1 1244 CDS 100% 15.000 10.500 N TXK n/a
12 TRCN0000194951 CAGTGATCCATGCATAGAATA pLKO.1 3061 3UTR 100% 13.200 9.240 N TXK n/a
13 TRCN0000194938 CAGTTCAACATGCATAGTAAA pLKO.1 2291 CDS 100% 13.200 9.240 N TXK n/a
14 TRCN0000314836 CAGTTCAACATGCATAGTAAA pLKO_005 2291 CDS 100% 13.200 9.240 N TXK n/a
15 TRCN0000121107 CCCTTGAAGAATTTCATGTTT pLKO.1 3121 3UTR 100% 5.625 3.938 N TXK n/a
16 TRCN0000194674 CCTGAGTTAATCTGGTATCAC pLKO.1 1770 CDS 100% 4.950 3.465 N TXK n/a
17 TRCN0000196365 GCACCTTTATAAATCACATGA pLKO.1 3170 3UTR 100% 4.950 3.465 N TXK n/a
18 TRCN0000314838 GCACCTTTATAAATCACATGA pLKO_005 3170 3UTR 100% 4.950 3.465 N TXK n/a
19 TRCN0000121177 GCCAACCCAAAGAGTCATCTT pLKO.1 2695 3UTR 100% 4.950 3.465 N TXK n/a
20 TRCN0000314784 GCCAACCCAAAGAGTCATCTT pLKO_005 2695 3UTR 100% 4.950 3.465 N TXK n/a
21 TRCN0000121288 GTCCATATATGAAGTCATGTA pLKO.1 2576 CDS 100% 4.950 3.465 N TXK n/a
22 TRCN0000001577 GAAACAGAATGCCAACCCAAA pLKO.1 2685 3UTR 100% 4.050 2.835 N TXK n/a
23 TRCN0000314837 GAAACAGAATGCCAACCCAAA pLKO_005 2685 3UTR 100% 4.050 2.835 N TXK n/a
24 TRCN0000121109 GCTTAACTATCTCAGGGAGAA pLKO.1 2150 CDS 100% 4.050 2.835 N TXK n/a
25 TRCN0000121291 TGCTGGCATGAGAAACCTGAA pLKO.1 2601 CDS 100% 4.050 2.835 N TXK n/a
26 TRCN0000001580 GCTGCCTGCTTAACTATCTCA pLKO.1 2143 CDS 100% 3.000 2.100 N TXK n/a
27 TRCN0000314783 GCTGCCTGCTTAACTATCTCA pLKO_005 2143 CDS 100% 3.000 2.100 N TXK n/a
28 TRCN0000121290 GTCAAATAAGAAGCAATCCAA pLKO.1 1256 CDS 100% 3.000 2.100 N TXK n/a
29 TRCN0000121179 GCTGTCACAGAGATTGCGGAA pLKO.1 2652 CDS 100% 2.160 1.512 N TXK n/a
30 TRCN0000009997 TACCTGATACTGGAGAAATAC pLKO.1 1422 CDS 100% 0.000 0.000 N TXK n/a
31 TRCN0000121178 CCAGGATATATGTGAAGGAAT pLKO.1 2210 CDS 100% 4.950 2.970 N TXK n/a
32 TRCN0000121287 CCCAAATGTGAAGAAGTGAAA pLKO.1 2919 3UTR 100% 4.950 2.970 N TXK n/a
33 TRCN0000001579 GAATACCTGATACTGGAGAAA pLKO.1 1419 CDS 100% 4.950 2.970 N TXK n/a
34 TRCN0000196461 GAAGAGAAGATCCAAGTCAAG pLKO.1 1341 CDS 100% 4.050 2.430 N TXK n/a
35 TRCN0000121289 GAGTGGTACCATAGAAACATT pLKO.1 1542 CDS 100% 0.000 0.000 N TXK n/a
36 TRCN0000166201 CATGGTGAAACCCTGTCTCTA pLKO.1 5037 3UTR 100% 4.950 2.475 Y ORAI2 n/a
37 TRCN0000256748 GGCAGGAGAATTGCTTGAATC pLKO_005 5126 3UTR 100% 10.800 5.400 Y SMIM11A n/a
38 TRCN0000179120 CAACATGGTGAAACCCTGTTT pLKO.1 5034 3UTR 100% 4.950 2.475 Y LOC339059 n/a
Download CSV

shRNA constructs with at least a near match to this transcript

This list includes shRNAs that have at least a >84% (16 of 19 bases) SDR[?] match to the transcript XM_017008581.2, regardless of what transcript they were originally designed to target. For example, this list can include shRNAs that were originally designed to target: (i) a different isoform or obsolete version of this transcript (as annotated by NCBI), (ii) a transcript of an orthologous gene (in this collection, generally human-to-mouse or mouse-to-human), or (iii) a transcript of a different gene (from the same or different taxon). NOTE: this download is a superset of the above result set.

Download CSV

All ORF constructs matching this transcript

Clone ID DNA Barcode Vector Sequenced %[?] Nuc. Match %[?] Prot. Match %[?] Epitope Tag Match Diffs[?] Addgene[?]
1 ccsbBroadEn_14869 pDONR223 0% 95.2% 95.2% None 0_1ins75 n/a
2 ccsbBroad304_14869 pLX_304 0% 95.2% 95.2% V5 0_1ins75 n/a
Download CSV

GPP Web Portal Terms of Service

Effective Date: December 8, 2025
By using this site, you agree to our terms and conditions below.

Overview of Terms

The data made available on this website were generated for research purposes and are not intended for clinical or commercial uses. Commercial use (or other use for profit-making purposes) of the GPP Web Portal and its tools, is not permitted under these terms and may require a separate license agreement from Broad or its contributors. For more information, please contact partnering@broadinstitute.org.

The original data may be subject to rights claimed by third parties, including but not limited to, patent, copyright, other intellectual property rights, biodiversity-related access and benefit-sharing rights. It is the responsibility of users of Broad Institute services to ensure that their use of the data does not infringe any of the rights of such third parties.

Any questions or comments concerning these Terms of Use can be addressed to: legal@broadinstitute.org.

By accessing and viewing this GPP Web Portal, you agree to the following terms and conditions:

Attribution

You agree to acknowledge the Broad Institute (e.g., in publications, services or products) for any of your use of its online services, databases or software in accordance with good scientific practice. You agree to use the acknowledgment wording provided for the relevant tools as indicated on the FAQ for each tool.

Updating the Terms of Use

We reserve the right to update these Terms of Use at any time. When alterations are inevitable, we will attempt to give reasonable notice of any changes by placing a notice on our website, but you may wish to check each time you use the website. The date of the most recent revision will appear on this, the "GPP Web Portal Terms of Use" page. If you do not agree to these changes, please do not continue to use our online services. We will also make available an archived copy of the previous Terms of Use for comparison.

Indemnification and Disclaimer of Warranties

You are using this GPP Web Portal at your own risk, and you hereby agree to hold Broad and its contributors and their trustees, directors, officers, employees, and affiliated investigators harmless for any third party claims which may arise from your use of the GPP Web Portal, the tools available therein, or any portion thereof. Further, you agree to indemnify Broad, its contributors, and its and their trustees, directors, officers, employees, affiliated investigators, students, and affiliates for any loss, costs, claims, damages, or other liabilities arising from any unpermitted commercial or profit-making use you make of the GPP Web Portal. The GPP Web Portal is a research tool and is provided "as is". Broad does not represent that the GPP Web Portal is free of errors or bugs or suitable for any particular tasks.

ANY EXPRESS OR IMPLIED WARRANTIES, INCLUDING, BUT NOT LIMITED TO, THE IMPLIED WARRANTIES OF MERCHANTABILITY, FITNESS FOR A PARTICULAR PURPOSE, NONINFRINGEMENT, OR THE ABSENCE OF LATENT OR OTHER DEFECTS ARE DISCLAIMED. IN NO EVENT SHALL BROAD OR ITS CONTRIBUTORS BE LIABLE FOR ANY DIRECT, INDIRECT, INCIDENTAL, SPECIAL, EXEMPLARY, OR CONSEQUENTIAL DAMAGES HOWEVER CAUSED AND ON ANY THEORY OF LIABILITY, WHETHER IN CONTRACT, STRICT LIABILITY, OR TORT (INCLUDING NEGLIGENCE OR OTHERWISE) ARISING IN ANY WAY OUT OF THE USE OF THE GPP WEB PORTAL, EVEN IF ADVISED OF THE POSSIBILITY OF SUCH DAMAGE.

Governing Law

The terms and conditions herein shall be construed, governed, interpreted, and applied in accordance with the internal laws of the Commonwealth of Massachusetts, U.S.A. Furthermore, by accessing, downloading, or using the Database, You consent to the personal jurisdiction of, and venue in, the state and federal courts within Massachusetts with respect to Your download or use of the Database.