Transcript: Human NM_004945.3

Homo sapiens dynamin 2 (DNM2), transcript variant 3, mRNA.

Source:
NCBI, updated 2019-09-25
Taxon:
Homo sapiens (human)
Gene:
DNM2 (1785)
Length:
3672
CDS:
191..2791

Additional Resources:

NCBI RefSeq record:
NM_004945.3
NBCI Gene record:
DNM2 (1785)

sgRNA constructs matching this transcript (CRISPRko, NGG PAM)

This list includes CRISPRko constructs with 100% (20mer + NGG) sequence match to the coding regions of this transcript.

No results found.

shRNA constructs matching this transcript with 100% SDR[?] match

This list includes all shRNAs that have a perfect SDR[?] match to Human NM_004945.3, regardless of what transcript they were originally designed to target. For example, this list can include shRNAs that were originally designed to target: (i) a different isoform or obsolete version of this transcript (as annotated by NCBI), (ii) a transcript of an orthologous gene (in this collection, generally human-to-mouse or mouse-to-human), or (iii) a transcript of a different gene (from the same or different taxon).

Clone ID Target Seq Vector Match Position Match Region[?] SDR Match %[?] Intrinsic Score[?] Adjusted Score[?] Matches Other Human Gene?[?] Orig. Target Gene[?] Addgene[?]
1 TRCN0000380880 GAGCGAATCGTCACCACTTAC pLKO_005 1559 CDS 100% 10.800 15.120 N DNM2 n/a
2 TRCN0000273534 GTTAGGCAGTGTACCAGTAAG pLKO_005 1505 CDS 100% 10.800 15.120 N DNM2 n/a
3 TRCN0000006650 GCGAATCGTCACCACTTACAT pLKO.1 1561 CDS 100% 5.625 7.875 N DNM2 n/a
4 TRCN0000006651 CCCGTTGAGAAGAGGCTACAT pLKO.1 865 CDS 100% 4.950 6.930 N DNM2 n/a
5 TRCN0000273535 CCCGTTGAGAAGAGGCTACAT pLKO_005 865 CDS 100% 4.950 6.930 N DNM2 n/a
6 TRCN0000006648 CCTGAGGTGTACATAGTCCTT pLKO.1 3288 3UTR 100% 2.640 3.696 N DNM2 n/a
7 TRCN0000006649 GCAGTCCTACATCAACACGAA pLKO.1 1636 CDS 100% 2.640 3.696 N DNM2 n/a
8 TRCN0000273537 GCAGTCCTACATCAACACGAA pLKO_005 1636 CDS 100% 2.640 3.696 N DNM2 n/a
9 TRCN0000381256 TGATCCCGCTGGTCAACAAAC pLKO_005 216 CDS 100% 10.800 8.640 N DNM2 n/a
10 TRCN0000273597 ATGTAGGGCAGGCCTTCTATA pLKO_005 3138 3UTR 100% 13.200 9.240 N DNM2 n/a
11 TRCN0000273595 ATCTGCAGAAGACGCTGAATC pLKO_005 1017 CDS 100% 10.800 7.560 N DNM2 n/a
12 TRCN0000380963 TTCCACGAGCGGTTCCCATTT pLKO_005 1286 CDS 100% 10.800 7.560 N DNM2 n/a
13 TRCN0000379640 TTCTTCTGCTGATCGACATTG pLKO_005 1614 CDS 100% 10.800 7.560 N DNM2 n/a
14 TRCN0000006652 GACAACCTCAAGATCCGTGAT pLKO.1 1880 CDS 100% 4.050 2.835 N DNM2 n/a
Download CSV

shRNA constructs with at least a near match to this transcript

This list includes shRNAs that have at least a >84% (16 of 19 bases) SDR[?] match to the transcript NM_004945.3, regardless of what transcript they were originally designed to target. For example, this list can include shRNAs that were originally designed to target: (i) a different isoform or obsolete version of this transcript (as annotated by NCBI), (ii) a transcript of an orthologous gene (in this collection, generally human-to-mouse or mouse-to-human), or (iii) a transcript of a different gene (from the same or different taxon). NOTE: this download is a superset of the above result set.

Download CSV

All ORF constructs matching this transcript

Clone ID DNA Barcode Vector Sequenced %[?] Nuc. Match %[?] Prot. Match %[?] Epitope Tag Match Diffs[?] Addgene[?]
1 ccsbBroadEn_06113 pDONR223 100% 99.5% 99.5% None 1544_1545insGGGGGAGATCCT;2127T>C n/a
2 ccsbBroad304_06113 pLX_304 0% 99.5% 99.5% V5 1544_1545insGGGGGAGATCCT;2127T>C n/a
3 TRCN0000477226 CCTTTCAAGCTCTGCTGCCATAGT pLX_317 16.5% 99.5% 99.5% V5 1544_1545insGGGGGAGATCCT;2127T>C n/a
Download CSV