Transcript: Human NM_000372.5

Homo sapiens tyrosinase (TYR), mRNA.

Source:
NCBI, updated 2019-08-22
Taxon:
Homo sapiens (human)
Gene:
TYR (7299)
Length:
2062
CDS:
80..1669

Additional Resources:

NCBI RefSeq record:
NM_000372.5
NBCI Gene record:
TYR (7299)

sgRNA constructs matching this transcript (CRISPRko, NGG PAM)

This list includes CRISPRko constructs with 100% (20mer + NGG) sequence match to the coding regions of this transcript.

No results found.

shRNA constructs matching this transcript with 100% SDR[?] match

This list includes all shRNAs that have a perfect SDR[?] match to Human NM_000372.5, regardless of what transcript they were originally designed to target. For example, this list can include shRNAs that were originally designed to target: (i) a different isoform or obsolete version of this transcript (as annotated by NCBI), (ii) a transcript of an orthologous gene (in this collection, generally human-to-mouse or mouse-to-human), or (iii) a transcript of a different gene (from the same or different taxon).

Clone ID Target Seq Vector Match Position Match Region[?] SDR Match %[?] Intrinsic Score[?] Adjusted Score[?] Matches Other Human Gene?[?] Orig. Target Gene[?] Addgene[?]
1 TRCN0000373834 CTTGTATCAGAGCCATTTATA pLKO_005 1648 CDS 100% 15.000 21.000 N TYR n/a
2 TRCN0000373918 AGACTACATTAAGTCCTATTT pLKO_005 1462 CDS 100% 13.200 9.240 N TYR n/a
3 TRCN0000083538 CCCATGTTTAACGACATCAAT pLKO.1 572 CDS 100% 5.625 3.938 N TYR n/a
4 TRCN0000083541 GCCTTGCACATCTATATGAAT pLKO.1 1172 CDS 100% 5.625 3.938 N TYR n/a
5 TRCN0000083539 GCCTTGGCATAGACTCTTCTT pLKO.1 703 CDS 100% 4.950 3.465 N TYR n/a
6 TRCN0000083540 CCATTGGACATAACCGGGAAT pLKO.1 1329 CDS 100% 4.050 2.835 N TYR n/a
7 TRCN0000083542 CTCTGGCAACTTCATGGGATT pLKO.1 352 CDS 100% 4.050 2.835 N TYR n/a
8 TRCN0000373833 TGCCTGAGTTTGACCCAATAT pLKO_005 1040 CDS 100% 13.200 7.920 N TYR n/a
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shRNA constructs with at least a near match to this transcript

This list includes shRNAs that have at least a >84% (16 of 19 bases) SDR[?] match to the transcript NM_000372.5, regardless of what transcript they were originally designed to target. For example, this list can include shRNAs that were originally designed to target: (i) a different isoform or obsolete version of this transcript (as annotated by NCBI), (ii) a transcript of an orthologous gene (in this collection, generally human-to-mouse or mouse-to-human), or (iii) a transcript of a different gene (from the same or different taxon). NOTE: this download is a superset of the above result set.

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All ORF constructs matching this transcript

Clone ID DNA Barcode Vector Sequenced %[?] Nuc. Match %[?] Prot. Match %[?] Epitope Tag Match Diffs[?] Addgene[?]
1 ccsbBroadEn_13974 pDONR223 100% 68% 65.9% None (many diffs) n/a
2 ccsbBroad304_13974 pLX_304 0% 68% 65.9% V5 (not translated due to frame shift) (many diffs) n/a
3 TRCN0000468742 TAGGCCAGTGGCTAGTGGCCCCAT pLX_317 37.8% 68% 65.9% V5 (not translated due to frame shift) (many diffs) n/a
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