Transcript: Human NM_001301198.1

Homo sapiens leucine rich repeat and Ig domain containing 1 (LINGO1), transcript variant 10, mRNA.

Source:
NCBI, updated 2019-09-22
Taxon:
Homo sapiens (human)
Gene:
LINGO1 (84894)
Length:
3091
CDS:
213..2057

Additional Resources:

NCBI RefSeq record:
NM_001301198.1
NBCI Gene record:
LINGO1 (84894)

sgRNA constructs matching this transcript (CRISPRko, NGG PAM)

This list includes CRISPRko constructs with 100% (20mer + NGG) sequence match to the coding regions of this transcript.

No results found.

shRNA constructs matching this transcript with 100% SDR[?] match

This list includes all shRNAs that have a perfect SDR[?] match to Human NM_001301198.1, regardless of what transcript they were originally designed to target. For example, this list can include shRNAs that were originally designed to target: (i) a different isoform or obsolete version of this transcript (as annotated by NCBI), (ii) a transcript of an orthologous gene (in this collection, generally human-to-mouse or mouse-to-human), or (iii) a transcript of a different gene (from the same or different taxon).

Clone ID Target Seq Vector Match Position Match Region[?] SDR Match %[?] Intrinsic Score[?] Adjusted Score[?] Matches Other Human Gene?[?] Orig. Target Gene[?] Addgene[?]
1 TRCN0000420812 ACACGCGGCAGAGTCAATAAT pLKO_005 2317 3UTR 100% 15.000 21.000 N LINGO1 n/a
2 TRCN0000434195 ACAACATCGAGATCGAGTATG pLKO_005 1966 CDS 100% 10.800 15.120 N LINGO1 n/a
3 TRCN0000174355 CGGCAGAGTCAATAATTCAAT pLKO.1 2322 3UTR 100% 5.625 7.875 N Lingo1 n/a
4 TRCN0000278640 CGGCAGAGTCAATAATTCAAT pLKO_005 2322 3UTR 100% 5.625 7.875 N Lingo1 n/a
5 TRCN0000157817 CGACAATGACCTCGTCTACAT pLKO.1 719 CDS 100% 4.950 6.930 N LINGO1 n/a
6 TRCN0000155383 CGTTATCCTACTGGACTACAT pLKO.1 659 CDS 100% 4.950 6.930 N LINGO1 n/a
7 TRCN0000426186 TGTAACTTGGGTTTCAATAAT pLKO_005 2364 3UTR 100% 15.000 10.500 N LINGO1 n/a
8 TRCN0000155707 CAGCGAGAACAAGATCGTTAT pLKO.1 644 CDS 100% 10.800 7.560 N LINGO1 n/a
9 TRCN0000435129 GCCCTCTTCCAACTCAGTTTC pLKO_005 2483 3UTR 100% 10.800 7.560 N LINGO1 n/a
10 TRCN0000175194 CTCTGTAACTTGGGTTTCAAT pLKO.1 2361 3UTR 100% 5.625 3.938 N Lingo1 n/a
11 TRCN0000297207 CTCTGTAACTTGGGTTTCAAT pLKO_005 2361 3UTR 100% 5.625 3.938 N Lingo1 n/a
12 TRCN0000157744 CAAGGGCAACACAAAGCACAA pLKO.1 1949 CDS 100% 4.050 2.835 N LINGO1 n/a
13 TRCN0000157960 CTTCGCTTTCATCTCCAACCA pLKO.1 1778 CDS 100% 2.640 1.848 N LINGO1 n/a
14 TRCN0000157197 GAAATGCAACCTGACCTCCAT pLKO.1 791 CDS 100% 2.640 1.848 N LINGO1 n/a
15 TRCN0000155622 CCGCAAGTTCAACATGAAGAT pLKO.1 2030 CDS 100% 4.950 2.970 N LINGO1 n/a
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shRNA constructs with at least a near match to this transcript

This list includes shRNAs that have at least a >84% (16 of 19 bases) SDR[?] match to the transcript NM_001301198.1, regardless of what transcript they were originally designed to target. For example, this list can include shRNAs that were originally designed to target: (i) a different isoform or obsolete version of this transcript (as annotated by NCBI), (ii) a transcript of an orthologous gene (in this collection, generally human-to-mouse or mouse-to-human), or (iii) a transcript of a different gene (from the same or different taxon). NOTE: this download is a superset of the above result set.

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All ORF constructs matching this transcript

Clone ID DNA Barcode Vector Sequenced %[?] Nuc. Match %[?] Prot. Match %[?] Epitope Tag Match Diffs[?] Addgene[?]
1 ccsbBroadEn_12871 pDONR223 100% 100% 100% None n/a
2 ccsbBroad304_12871 pLX_304 0% 100% 100% V5 n/a
3 TRCN0000469832 AATGATGTAGTCCGTCATCCTCAA pLX_317 22.8% 100% 100% V5 n/a
4 ccsbBroadEn_12872 pDONR223 100% 99.7% 99.5% None (many diffs) n/a
5 ccsbBroad304_12872 pLX_304 0% 99.7% 99.5% V5 (many diffs) n/a
6 TRCN0000469736 CAGGGCGGACAGGCGCGGCTATTC pLX_317 22.8% 99.7% 99.5% V5 (many diffs) n/a
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