Transcript: Human NM_022457.7

Homo sapiens COP1 E3 ubiquitin ligase (COP1), transcript variant 1, mRNA.

Source:
NCBI, updated 2019-09-16
Taxon:
Homo sapiens (human)
Gene:
COP1 (64326)
Length:
2826
CDS:
309..2504

Additional Resources:

NCBI RefSeq record:
NM_022457.7
NBCI Gene record:
COP1 (64326)

sgRNA constructs matching this transcript (CRISPRko, NGG PAM)

This list includes CRISPRko constructs with 100% (20mer + NGG) sequence match to the coding regions of this transcript.

No results found.

shRNA constructs matching this transcript with 100% SDR[?] match

This list includes all shRNAs that have a perfect SDR[?] match to Human NM_022457.7, regardless of what transcript they were originally designed to target. For example, this list can include shRNAs that were originally designed to target: (i) a different isoform or obsolete version of this transcript (as annotated by NCBI), (ii) a transcript of an orthologous gene (in this collection, generally human-to-mouse or mouse-to-human), or (iii) a transcript of a different gene (from the same or different taxon).

Clone ID Target Seq Vector Match Position Match Region[?] SDR Match %[?] Intrinsic Score[?] Adjusted Score[?] Matches Other Human Gene?[?] Orig. Target Gene[?] Addgene[?]
1 TRCN0000029721 GCTAACAGTCAGGGTACAATT pLKO.1 2463 CDS 100% 13.200 18.480 N COP1 n/a
2 TRCN0000343404 GCTAACAGTCAGGGTACAATT pLKO_005 2463 CDS 100% 13.200 18.480 N COP1 n/a
3 TRCN0000029720 CCTTGGTATAATAGCACGTTA pLKO.1 1347 CDS 100% 4.950 6.930 N COP1 n/a
4 TRCN0000343444 CCTTGGTATAATAGCACGTTA pLKO_005 1347 CDS 100% 4.950 6.930 N COP1 n/a
5 TRCN0000041086 GCTGTATCAGTTGGAGTAGTT pLKO.1 1729 CDS 100% 4.950 3.960 N Rfwd2 n/a
6 TRCN0000363790 GCTGTATCAGTTGGAGTAGTT pLKO_005 1729 CDS 100% 4.950 3.960 N Rfwd2 n/a
7 TRCN0000029719 CCACCATCAATGTAACTCCAT pLKO.1 2703 3UTR 100% 2.640 2.112 N COP1 n/a
8 TRCN0000343446 CCACCATCAATGTAACTCCAT pLKO_005 2703 3UTR 100% 2.640 2.112 N COP1 n/a
9 TRCN0000235227 CAGAGTTTGGAGGACAATAAT pLKO_005 792 CDS 100% 15.000 10.500 N EG667784 n/a
10 TRCN0000029722 GCAGCCCAACTACAGATTCTT pLKO.1 1080 CDS 100% 5.625 3.938 N COP1 n/a
11 TRCN0000029723 GCTGGAGTTACAAAGAAGATT pLKO.1 1623 CDS 100% 5.625 3.938 N COP1 n/a
12 TRCN0000343445 GCTGGAGTTACAAAGAAGATT pLKO_005 1623 CDS 100% 5.625 3.938 N COP1 n/a
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shRNA constructs with at least a near match to this transcript

This list includes shRNAs that have at least a >84% (16 of 19 bases) SDR[?] match to the transcript NM_022457.7, regardless of what transcript they were originally designed to target. For example, this list can include shRNAs that were originally designed to target: (i) a different isoform or obsolete version of this transcript (as annotated by NCBI), (ii) a transcript of an orthologous gene (in this collection, generally human-to-mouse or mouse-to-human), or (iii) a transcript of a different gene (from the same or different taxon). NOTE: this download is a superset of the above result set.

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All ORF constructs matching this transcript

Clone ID DNA Barcode Vector Sequenced %[?] Nuc. Match %[?] Prot. Match %[?] Epitope Tag Match Diffs[?] Addgene[?]
1 ccsbBroadEn_03940 pDONR223 100% 100% 100% None n/a
2 ccsbBroad304_03940 pLX_304 0% 100% 100% V5 n/a
3 TRCN0000477822 GATACAACGGCCTAGATGTACCAA pLX_317 18.3% 100% 100% V5 n/a
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