Transcript: Human NM_139021.3

Homo sapiens mitogen-activated protein kinase 15 (MAPK15), mRNA.

Source:
NCBI, updated 2019-05-02
Taxon:
Homo sapiens (human)
Gene:
MAPK15 (225689)
Length:
1871
CDS:
30..1664

Additional Resources:

NCBI RefSeq record:
NM_139021.3
NBCI Gene record:
MAPK15 (225689)

shRNA constructs matching this transcript with 100% SDR[?] match

This list includes all shRNAs that have a perfect SDR[?] match to Human NM_139021.3, regardless of what transcript they were originally designed to target. For example, this list can include shRNAs that were originally designed to target: (i) a different isoform or obsolete version of this transcript (as annotated by NCBI), (ii) a transcript of an orthologous gene (in this collection, generally human-to-mouse or mouse-to-human), or (iii) a transcript of a different gene (from the same or different taxon).

Clone ID Target Seq Vector Match Position Match Region[?] SDR Match %[?] Intrinsic Score[?] Adjusted Score[?] Matches Other Human Gene?[?] Orig. Target Gene[?] Addgene[?]
1 TRCN0000002214 AGAGAACGACAGGGACATTTA pLKO.1 275 CDS 100% 13.200 18.480 N MAPK15 n/a
2 TRCN0000199135 CACTGACCTGAACGCAGTCAT pLKO.1 317 CDS 100% 4.950 6.930 N MAPK15 n/a
3 TRCN0000344522 CACTGACCTGAACGCAGTCAT pLKO_005 317 CDS 100% 4.950 6.930 N MAPK15 n/a
4 TRCN0000199687 GCCGCGTCTATCAGATGATCC pLKO.1 1039 CDS 100% 1.350 1.890 N MAPK15 n/a
5 TRCN0000344587 GCCGCGTCTATCAGATGATCC pLKO_005 1039 CDS 100% 1.350 1.890 N MAPK15 n/a
6 TRCN0000199159 CCTACGGGACTGTCTGCCACT pLKO.1 1600 CDS 100% 0.000 0.000 N MAPK15 n/a
7 TRCN0000038659 CCAGAGAACATTCCGGGAAAT pLKO.1 191 CDS 100% 10.800 14.040 N MAPK15 n/a
8 TRCN0000002213 CCACTGACTTCCTCCAATAAA pLKO.1 1834 3UTR 100% 15.000 12.000 N MAPK15 n/a
9 TRCN0000038662 CCGTCCAATGTGCTCCTGGAT pLKO.1 447 CDS 100% 0.880 0.704 N MAPK15 n/a
10 TRCN0000332982 CCGTCCAATGTGCTCCTGGAT pLKO_005 447 CDS 100% 0.880 0.704 N MAPK15 n/a
11 TRCN0000344589 TTACCTGGTGTTTGAGTTTAT pLKO_005 293 CDS 100% 13.200 9.240 N MAPK15 n/a
12 TRCN0000344588 ACAGATGCCCAGAGAACATTC pLKO_005 183 CDS 100% 10.800 7.560 N MAPK15 n/a
13 TRCN0000038660 AGGGACATTTACCTGGTGTTT pLKO.1 285 CDS 100% 4.950 3.465 N MAPK15 n/a
14 TRCN0000002212 ATAAGACAGATGCCCAGAGAA pLKO.1 178 CDS 100% 4.950 3.465 N MAPK15 n/a
15 TRCN0000038663 GCAGAGAACGACAGGGACATT pLKO.1 273 CDS 100% 4.950 3.465 N MAPK15 n/a
16 TRCN0000199134 CAAACTGCTCTCCTAGGGAAT pLKO.1 1287 CDS 100% 4.050 2.835 N MAPK15 n/a
17 TRCN0000199957 GCCTATGGCATTGTGTGGAAG pLKO.1 96 CDS 100% 4.050 2.835 N MAPK15 n/a
18 TRCN0000038661 GCTGCTCTCTTCGCACCGATA pLKO.1 593 CDS 100% 1.350 0.945 N MAPK15 n/a
19 TRCN0000199073 CCGGAGGATGTTCAGCACCTC pLKO.1 1523 CDS 100% 0.000 0.000 N MAPK15 n/a
Download CSV

shRNA constructs with at least a near match to this transcript

This list includes shRNAs that have at least a >84% (16 of 19 bases) SDR[?] match to the transcript NM_139021.3, regardless of what transcript they were originally designed to target. For example, this list can include shRNAs that were originally designed to target: (i) a different isoform or obsolete version of this transcript (as annotated by NCBI), (ii) a transcript of an orthologous gene (in this collection, generally human-to-mouse or mouse-to-human), or (iii) a transcript of a different gene (from the same or different taxon). NOTE: this download is a superset of the above result set.

Download CSV

All ORF constructs matching this transcript

Clone ID DNA Barcode Vector Sequenced %[?] Nuc. Match %[?] Prot. Match %[?] Epitope Tag Match Diffs[?] Addgene[?]
1 TRCN0000488616 GCTGCGAAAACTGGTTGGAGTGAT pLX_317 15% 100% 100% V5 n/a
2 TRCN0000489042 TAACCAACGAGCTATTCGTATTTG pLX_317 18.7% 100% 100% V5 (not translated due to prior stop codon) n/a
3 ccsbBroadEn_13442 pDONR223 100% 46.2% 46.3% None 285_286ins51;498C>T;781_1632del n/a
4 ccsbBroad304_13442 pLX_304 0% 46.2% 46.3% V5 285_286ins51;498C>T;781_1632del n/a
5 TRCN0000472496 GTTTGCACAACACTACCCAGAAGC pLX_317 50.1% 46.2% 46.3% V5 285_286ins51;498C>T;781_1632del n/a
6 ccsbBroadEn_15292 pDONR223 0% 46.2% 46.3% None 285_286ins51;498C>T;781_1632del n/a
7 ccsbBroad304_15292 pLX_304 0% 46.2% 46.3% V5 285_286ins51;498C>T;781_1632del n/a
8 TRCN0000466886 AGCTTAAAAACTGCCTTGGATCCA pLX_317 49.4% 46.2% 46.3% V5 285_286ins51;498C>T;781_1632del n/a
9 TRCN0000487795 GTTGGATCTCCTAGATTATTCGTA pLX_317 30% 46.2% 46.3% V5 (not translated due to prior stop codon) 285_286ins51;498C>T;781_1632del n/a
Download CSV

GPP Web Portal Terms of Service

Effective Date: December 8, 2025
By using this site, you agree to our terms and conditions below.

Overview of Terms

The data made available on this website were generated for research purposes and are not intended for clinical or commercial uses. Commercial use (or other use for profit-making purposes) of the GPP Web Portal and its tools, is not permitted under these terms and may require a separate license agreement from Broad or its contributors. For more information, please contact partnering@broadinstitute.org.

The original data may be subject to rights claimed by third parties, including but not limited to, patent, copyright, other intellectual property rights, biodiversity-related access and benefit-sharing rights. It is the responsibility of users of Broad Institute services to ensure that their use of the data does not infringe any of the rights of such third parties.

Any questions or comments concerning these Terms of Use can be addressed to: legal@broadinstitute.org.

By accessing and viewing this GPP Web Portal, you agree to the following terms and conditions:

Attribution

You agree to acknowledge the Broad Institute (e.g., in publications, services or products) for any of your use of its online services, databases or software in accordance with good scientific practice. You agree to use the acknowledgment wording provided for the relevant tools as indicated on the FAQ for each tool.

Updating the Terms of Use

We reserve the right to update these Terms of Use at any time. When alterations are inevitable, we will attempt to give reasonable notice of any changes by placing a notice on our website, but you may wish to check each time you use the website. The date of the most recent revision will appear on this, the "GPP Web Portal Terms of Use" page. If you do not agree to these changes, please do not continue to use our online services. We will also make available an archived copy of the previous Terms of Use for comparison.

Indemnification and Disclaimer of Warranties

You are using this GPP Web Portal at your own risk, and you hereby agree to hold Broad and its contributors and their trustees, directors, officers, employees, and affiliated investigators harmless for any third party claims which may arise from your use of the GPP Web Portal, the tools available therein, or any portion thereof. Further, you agree to indemnify Broad, its contributors, and its and their trustees, directors, officers, employees, affiliated investigators, students, and affiliates for any loss, costs, claims, damages, or other liabilities arising from any unpermitted commercial or profit-making use you make of the GPP Web Portal. The GPP Web Portal is a research tool and is provided "as is". Broad does not represent that the GPP Web Portal is free of errors or bugs or suitable for any particular tasks.

ANY EXPRESS OR IMPLIED WARRANTIES, INCLUDING, BUT NOT LIMITED TO, THE IMPLIED WARRANTIES OF MERCHANTABILITY, FITNESS FOR A PARTICULAR PURPOSE, NONINFRINGEMENT, OR THE ABSENCE OF LATENT OR OTHER DEFECTS ARE DISCLAIMED. IN NO EVENT SHALL BROAD OR ITS CONTRIBUTORS BE LIABLE FOR ANY DIRECT, INDIRECT, INCIDENTAL, SPECIAL, EXEMPLARY, OR CONSEQUENTIAL DAMAGES HOWEVER CAUSED AND ON ANY THEORY OF LIABILITY, WHETHER IN CONTRACT, STRICT LIABILITY, OR TORT (INCLUDING NEGLIGENCE OR OTHERWISE) ARISING IN ANY WAY OUT OF THE USE OF THE GPP WEB PORTAL, EVEN IF ADVISED OF THE POSSIBILITY OF SUCH DAMAGE.

Governing Law

The terms and conditions herein shall be construed, governed, interpreted, and applied in accordance with the internal laws of the Commonwealth of Massachusetts, U.S.A. Furthermore, by accessing, downloading, or using the Database, You consent to the personal jurisdiction of, and venue in, the state and federal courts within Massachusetts with respect to Your download or use of the Database.