Transcript: Human XM_024449913.1

PREDICTED: Homo sapiens insulin like growth factor 1 receptor (IGF1R), transcript variant X5, mRNA.

Source:
NCBI, updated 2019-09-08
Taxon:
Homo sapiens (human)
Gene:
IGF1R (3480)
Length:
4712
CDS:
434..3628

Additional Resources:

NCBI RefSeq record:
XM_024449913.1
NBCI Gene record:
IGF1R (3480)

shRNA constructs matching this transcript with 100% SDR[?] match

This list includes all shRNAs that have a perfect SDR[?] match to Human XM_024449913.1, regardless of what transcript they were originally designed to target. For example, this list can include shRNAs that were originally designed to target: (i) a different isoform or obsolete version of this transcript (as annotated by NCBI), (ii) a transcript of an orthologous gene (in this collection, generally human-to-mouse or mouse-to-human), or (iii) a transcript of a different gene (from the same or different taxon).

Clone ID Target Seq Vector Match Position Match Region[?] SDR Match %[?] Intrinsic Score[?] Adjusted Score[?] Matches Other Human Gene?[?] Orig. Target Gene[?] Addgene[?]
1 TRCN0000121196 GCTGTACGTCTTCCATAGAAA pLKO.1 2386 CDS 100% 5.625 7.875 N IGF1R n/a
2 TRCN0000039674 CGGCACAATTACTGCTCCAAA pLKO.1 1499 CDS 100% 4.950 6.930 N IGF1R n/a
3 TRCN0000000424 GCTGATGTGTACGTTCCTGAT pLKO.1 2474 CDS 100% 4.050 5.670 N IGF1R n/a
4 TRCN0000121297 CCTCTCTGCTTCATAACGGAA pLKO.1 3963 3UTR 100% 2.640 3.696 N IGF1R n/a
5 TRCN0000039677 GCCTTTCACATTGTACCGCAT pLKO.1 1906 CDS 100% 2.160 3.024 N IGF1R n/a
6 TRCN0000121192 CCTGAATCTGTGCAAACAGTA pLKO.1 3638 3UTR 100% 4.950 3.960 N IGF1R n/a
7 TRCN0000121298 CGACAGACACTCAGGACACAA pLKO.1 3475 CDS 100% 4.950 3.960 N IGF1R n/a
8 TRCN0000121301 CGGCAACCTGAGTTACTACAT pLKO.1 1438 CDS 100% 4.950 3.960 N IGF1R n/a
9 TRCN0000195002 CAACACTTAATAGCAACAGAG pLKO.1 3883 3UTR 100% 4.050 3.240 N IGF1R n/a
10 TRCN0000018331 CATGTACTGCATCCCTTGTGA pLKO.1 478 CDS 100% 3.000 2.400 N IGF1R n/a
11 TRCN0000121134 CAAGGGCAATTTGCTCATTAA pLKO.1 592 CDS 100% 13.200 9.240 N IGF1R n/a
12 TRCN0000199517 GCGCATGTGCTGGCAGTATAA pLKO.1 3259 CDS 100% 13.200 9.240 N IGF1R n/a
13 TRCN0000000423 GCTACCTTTACCGGCACAATT pLKO.1 1488 CDS 100% 13.200 9.240 N IGF1R n/a
14 TRCN0000121195 GTCTTCCATAGAAAGAGAAAT pLKO.1 2393 CDS 100% 13.200 9.240 N IGF1R n/a
15 TRCN0000000426 CCAAGCCTGAGCAAGATGATT pLKO.1 2843 CDS 100% 5.625 3.938 N IGF1R n/a
16 TRCN0000121132 CCTTTATCTTTCACCTTTCTA pLKO.1 4127 3UTR 100% 5.625 3.938 N IGF1R n/a
17 TRCN0000121135 GAGACAGAGTACCCTTTCTTT pLKO.1 1838 CDS 100% 5.625 3.938 N IGF1R n/a
18 TRCN0000121136 CCAAGGATGCACCATCTTCAA pLKO.1 574 CDS 100% 4.950 3.465 N IGF1R n/a
19 TRCN0000039675 GCCGAAGATTTCACAGTCAAA pLKO.1 2954 CDS 100% 4.950 3.465 N IGF1R n/a
20 TRCN0000039676 CCAAATTATGTGTTTCCGAAA pLKO.1 879 CDS 100% 4.050 2.835 N IGF1R n/a
21 TRCN0000000422 CCTTAACTGACATGGGCCTTT pLKO.1 3848 3UTR 100% 4.050 2.835 N IGF1R n/a
22 TRCN0000121299 CTTCTACTACAGCGAGGAGAA pLKO.1 3358 CDS 100% 4.050 2.835 N IGF1R n/a
23 TRCN0000000425 CCTTGGACGTTCTTTCAGCAT pLKO.1 1365 CDS 100% 2.640 1.848 N IGF1R n/a
24 TRCN0000010361 AAACACATTTGGGATGTTCCT pLKO.1 3787 3UTR 100% 0.000 0.000 N IGF1R n/a
25 TRCN0000039673 AACACATTTGGGATGTTCCTC pLKO.1 3788 3UTR 100% 0.000 0.000 N IGF1R n/a
Download CSV

shRNA constructs with at least a near match to this transcript

This list includes shRNAs that have at least a >84% (16 of 19 bases) SDR[?] match to the transcript XM_024449913.1, regardless of what transcript they were originally designed to target. For example, this list can include shRNAs that were originally designed to target: (i) a different isoform or obsolete version of this transcript (as annotated by NCBI), (ii) a transcript of an orthologous gene (in this collection, generally human-to-mouse or mouse-to-human), or (iii) a transcript of a different gene (from the same or different taxon). NOTE: this download is a superset of the above result set.

Download CSV

All ORF constructs matching this transcript

Clone ID DNA Barcode Vector Sequenced %[?] Nuc. Match %[?] Prot. Match %[?] Epitope Tag Match Diffs[?] Addgene[?]
1 ccsbBroadEn_14671 pDONR223 0% 77.8% 77.8% None 0_1ins909 n/a
2 ccsbBroad304_14671 pLX_304 0% 77.8% 77.8% V5 0_1ins909 n/a
3 TRCN0000473406 AAAATCAGCCCATACACAGGGTTC pLX_317 10.2% 77.8% 77.8% V5 0_1ins909;3075C>T n/a
4 TRCN0000489071 TCACACATTATGCGGGCCCCCCCC pLX_317 7% 77.8% 77.8% V5 (not translated due to prior stop codon) 0_1ins909 n/a
5 TRCN0000489368 CCGATGCCTGTCGCCGTCTGGTGA pLX_317 8.2% 77.8% 77.7% V5 0_1ins909;3192_3193insG n/a
6 TRCN0000489182 GGGCACACGGTCTCTGTGCCATAC pLX_317 33.6% 35.9% .4% V5 (not translated due to prior stop codon) 1_2044del n/a
Download CSV

GPP Web Portal Terms of Service

Effective Date: December 8, 2025
By using this site, you agree to our terms and conditions below.

Overview of Terms

The data made available on this website were generated for research purposes and are not intended for clinical or commercial uses. Commercial use (or other use for profit-making purposes) of the GPP Web Portal and its tools, is not permitted under these terms and may require a separate license agreement from Broad or its contributors. For more information, please contact partnering@broadinstitute.org.

The original data may be subject to rights claimed by third parties, including but not limited to, patent, copyright, other intellectual property rights, biodiversity-related access and benefit-sharing rights. It is the responsibility of users of Broad Institute services to ensure that their use of the data does not infringe any of the rights of such third parties.

Any questions or comments concerning these Terms of Use can be addressed to: legal@broadinstitute.org.

By accessing and viewing this GPP Web Portal, you agree to the following terms and conditions:

Attribution

You agree to acknowledge the Broad Institute (e.g., in publications, services or products) for any of your use of its online services, databases or software in accordance with good scientific practice. You agree to use the acknowledgment wording provided for the relevant tools as indicated on the FAQ for each tool.

Updating the Terms of Use

We reserve the right to update these Terms of Use at any time. When alterations are inevitable, we will attempt to give reasonable notice of any changes by placing a notice on our website, but you may wish to check each time you use the website. The date of the most recent revision will appear on this, the "GPP Web Portal Terms of Use" page. If you do not agree to these changes, please do not continue to use our online services. We will also make available an archived copy of the previous Terms of Use for comparison.

Indemnification and Disclaimer of Warranties

You are using this GPP Web Portal at your own risk, and you hereby agree to hold Broad and its contributors and their trustees, directors, officers, employees, and affiliated investigators harmless for any third party claims which may arise from your use of the GPP Web Portal, the tools available therein, or any portion thereof. Further, you agree to indemnify Broad, its contributors, and its and their trustees, directors, officers, employees, affiliated investigators, students, and affiliates for any loss, costs, claims, damages, or other liabilities arising from any unpermitted commercial or profit-making use you make of the GPP Web Portal. The GPP Web Portal is a research tool and is provided "as is". Broad does not represent that the GPP Web Portal is free of errors or bugs or suitable for any particular tasks.

ANY EXPRESS OR IMPLIED WARRANTIES, INCLUDING, BUT NOT LIMITED TO, THE IMPLIED WARRANTIES OF MERCHANTABILITY, FITNESS FOR A PARTICULAR PURPOSE, NONINFRINGEMENT, OR THE ABSENCE OF LATENT OR OTHER DEFECTS ARE DISCLAIMED. IN NO EVENT SHALL BROAD OR ITS CONTRIBUTORS BE LIABLE FOR ANY DIRECT, INDIRECT, INCIDENTAL, SPECIAL, EXEMPLARY, OR CONSEQUENTIAL DAMAGES HOWEVER CAUSED AND ON ANY THEORY OF LIABILITY, WHETHER IN CONTRACT, STRICT LIABILITY, OR TORT (INCLUDING NEGLIGENCE OR OTHERWISE) ARISING IN ANY WAY OUT OF THE USE OF THE GPP WEB PORTAL, EVEN IF ADVISED OF THE POSSIBILITY OF SUCH DAMAGE.

Governing Law

The terms and conditions herein shall be construed, governed, interpreted, and applied in accordance with the internal laws of the Commonwealth of Massachusetts, U.S.A. Furthermore, by accessing, downloading, or using the Database, You consent to the personal jurisdiction of, and venue in, the state and federal courts within Massachusetts with respect to Your download or use of the Database.