Transcript: Human NR_110451.1

Homo sapiens proprotein convertase subtilisin/kexin type 9 (PCSK9), transcript variant 2, non-coding RNA.

Source:
NCBI, updated 2019-09-03
Taxon:
Homo sapiens (human)
Gene:
PCSK9 (255738)
Length:
2976
CDS:
(non-coding)

Additional Resources:

NCBI RefSeq record:
NR_110451.1
NBCI Gene record:
PCSK9 (255738)

sgRNA constructs matching this transcript (CRISPRko, NGG PAM)

This list includes CRISPRko constructs with 100% (20mer + NGG) sequence match to the exonic sequence of this non-coding transcript.

No results found.

shRNA constructs matching this transcript with 100% SDR[?] match

This list includes all shRNAs that have a perfect SDR[?] match to Human NR_110451.1, regardless of what transcript they were originally designed to target. For example, this list can include shRNAs that were originally designed to target: (i) a different isoform or obsolete version of this transcript (as annotated by NCBI), (ii) a transcript of an orthologous gene (in this collection, generally human-to-mouse or mouse-to-human), or (iii) a transcript of a different gene (from the same or different taxon).

Clone ID Target Seq Vector Match Position Match Region[?] SDR Match %[?] Intrinsic Score[?] Adjusted Score[?] Matches Other Human Gene?[?] Orig. Target Gene[?] Addgene[?]
1 TRCN0000415303 GTTCCGTGCCAGGCATTCAAT pLKO_005 2027 3UTR 100% 5.625 7.875 N PCSK9 n/a
2 TRCN0000075236 GCCGTAGACAACACGTGTGTA pLKO.1 1552 3UTR 100% 4.950 3.960 N PCSK9 n/a
3 TRCN0000075235 CGTGCTCAACTGCCAAGGGAA pLKO.1 412 3UTR 100% 0.880 0.704 N PCSK9 n/a
4 TRCN0000417167 ACAGAGTGACCACCGGGAAAT pLKO_005 226 3UTR 100% 10.800 7.560 N PCSK9 n/a
5 TRCN0000435152 ATCCACTTCTCTGCCAAAGAT pLKO_005 905 3UTR 100% 5.625 3.938 N PCSK9 n/a
6 TRCN0000075233 GCCACCTTTACTCTGCTCTAT pLKO.1 2295 3UTR 100% 4.950 3.465 N PCSK9 n/a
7 TRCN0000075237 GCCAGCAAGTGTGACAGTCAT pLKO.1 317 3UTR 100% 4.950 3.465 N PCSK9 n/a
8 TRCN0000075234 GAATGCAAAGTCAAGGAGCAT pLKO.1 1426 3UTR 100% 2.640 1.584 N PCSK9 n/a
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shRNA constructs with at least a near match to this transcript

This list includes shRNAs that have at least a >84% (16 of 19 bases) SDR[?] match to the transcript NR_110451.1, regardless of what transcript they were originally designed to target. For example, this list can include shRNAs that were originally designed to target: (i) a different isoform or obsolete version of this transcript (as annotated by NCBI), (ii) a transcript of an orthologous gene (in this collection, generally human-to-mouse or mouse-to-human), or (iii) a transcript of a different gene (from the same or different taxon). NOTE: this download is a superset of the above result set.

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All ORF constructs matching this transcript

Clone ID DNA Barcode Vector Sequenced %[?] Nuc. Match %[?] Prot. Match %[?] Epitope Tag Match Diffs[?] Addgene[?]
1 TRCN0000488489 CAGATGTTACAGAACTCGCAGTAA pLX_317 14.6% 49.8% V5 (many diffs) n/a
2 TRCN0000489056 CCATAGAGTTGCCGGGGTCTGTTA pLX_317 22.5% 49.8% V5 (not translated due to prior stop codon) (many diffs) n/a
3 TRCN0000488467 CTCGGTTCTCGAAAGGGAATATCG pLX_317 17.8% 48% V5 (many diffs) n/a
4 TRCN0000487887 CGATTGACTCAAATGCGTGCGTAA pLX_317 14.9% 48% V5 (not translated due to prior stop codon) (many diffs) n/a
5 TRCN0000487988 TCACGCTACTACGAAGTGGAATCA pLX_317 34.2% 28.6% V5 (many diffs) n/a
6 TRCN0000488825 ACGCTCAATGAGTGCACGCTCACC pLX_317 34.5% 28.6% V5 (not translated due to prior stop codon) (many diffs) n/a
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