pB01 program activity among B cells

Activation of pB01
pB01 gene program activation in B cells.
Gene program activation of pB01 by different cell subtypes
pB01 gene program activation among cells of different subtypes (B cells).

pB01 top program genes

Top genes of pB01 program
Bar plots showing the top genes for each gene program, ranked by (left) unique weights, (right) raw weights.

pB01 gene-set enrichment of top program genes (using g-profiler)

GSEA wth gene profiler of pB01
pB01 gene-set enrichment summary using g-profiler webtool.
Source termID Name Padj Tsize Qsize Overlap Precision Recall
GO:BP GO:0006955 immune response 1.6250001307297e-15 2311 143 61 0.426573426573427 0.0263954997836434
GO:BP GO:0002376 immune system process 1.19300449185999e-14 3278 143 71 0.496503496503497 0.0216595485051861
GO:BP GO:0036230 granulocyte activation 8.41444035567175e-10 504 141 24 0.170212765957447 0.0476190476190476
GO:BP GO:0042119 neutrophil activation 8.41444035567175e-10 498 141 24 0.170212765957447 0.0481927710843374
GO:BP GO:0045321 leukocyte activation 3.47060557362704e-09 1332 141 37 0.26241134751773 0.0277777777777778
GO:BP GO:0019221 cytokine-mediated signaling pathway 9.06384821185034e-09 810 139 28 0.201438848920863 0.0345679012345679
GO:BP GO:0002283 neutrophil activation involved in immune response 9.39368541878984e-09 485 141 22 0.156028368794326 0.045360824742268
GO:BP GO:0043312 neutrophil degranulation 9.39368541878984e-09 482 141 22 0.156028368794326 0.045643153526971
GO:BP GO:0043299 leukocyte degranulation 9.39368541878984e-09 535 141 23 0.163120567375887 0.0429906542056075
GO:BP GO:0001775 cell activation 1.17655639776552e-08 1495 141 38 0.269503546099291 0.0254180602006689
GO:BP GO:0002446 neutrophil mediated immunity 1.23268565695143e-08 497 141 22 0.156028368794326 0.0442655935613682
GO:BP GO:0002444 myeloid leukocyte mediated immunity 1.25732736195955e-08 551 141 23 0.163120567375887 0.0417422867513612
GO:BP GO:0002274 myeloid leukocyte activation 1.5051282874795e-08 667 141 25 0.177304964539007 0.0374812593703148
GO:BP GO:0002252 immune effector process 1.55478989653864e-08 1309 141 35 0.24822695035461 0.0267379679144385
GO:BP GO:0002443 leukocyte mediated immunity 3.27335379409366e-08 877 141 28 0.198581560283688 0.031927023945268
GO:BP GO:0002366 leukocyte activation involved in immune response 5.268447313606e-08 717 141 25 0.177304964539007 0.0348675034867503
GO:BP GO:0002275 myeloid cell activation involved in immune response 5.268447313606e-08 547 141 22 0.156028368794326 0.0402193784277879
GO:BP GO:0002263 cell activation involved in immune response 5.29354300448482e-08 721 141 25 0.177304964539007 0.0346740638002774
GO:BP GO:0006887 exocytosis 5.29354300448482e-08 904 141 28 0.198581560283688 0.0309734513274336
GO:BP GO:0045055 regulated exocytosis 5.65127463673291e-08 785 141 26 0.184397163120567 0.0331210191082803
GO:BP GO:0071345 cellular response to cytokine stimulus 2.76474008771041e-07 1132 139 30 0.215827338129496 0.0265017667844523
GO:BP GO:0044419 biological process involved in interspecies interaction between organisms 1.44544002280001e-06 2255 121 39 0.322314049586777 0.0172949002217295
GO:BP GO:0034097 response to cytokine 1.59420520516799e-06 1226 139 30 0.215827338129496 0.0244698205546493
GO:BP GO:0002682 regulation of immune system process 1.64164650850014e-06 1617 139 35 0.251798561151079 0.0216450216450216
GO:BP GO:0060337 type I interferon signaling pathway 6.35319042334465e-06 95 139 9 0.0647482014388489 0.0947368421052632
GO:BP GO:0071357 cellular response to type I interferon 6.69730259002311e-06 96 139 9 0.0647482014388489 0.09375
GO:BP GO:0034340 response to type I interferon 1.00569773190287e-05 101 139 9 0.0647482014388489 0.0891089108910891
GO:BP GO:0050776 regulation of immune response 1.67824325189196e-05 996 139 25 0.179856115107914 0.0251004016064257
GO:BP GO:0006915 apoptotic process 2.54872104988323e-05 1990 128 35 0.2734375 0.0175879396984925
GO:BP GO:0034341 response to interferon-gamma 3.72909507255144e-05 196 139 11 0.079136690647482 0.0561224489795918
GO:BP GO:0070887 cellular response to chemical stimulus 4.04969067613963e-05 3393 142 52 0.366197183098592 0.0153256704980843
GO:BP GO:0006952 defense response 4.84217633474221e-05 1818 113 30 0.265486725663717 0.0165016501650165
GO:BP GO:0044403 biological process involved in symbiotic interaction 4.9565897095381e-05 1001 128 23 0.1796875 0.022977022977023
GO:BP GO:0032940 secretion by cell 5.52282159949773e-05 1364 141 29 0.205673758865248 0.0212609970674487
GO:BP GO:0016032 viral process 6.55078766029922e-05 942 128 22 0.171875 0.0233545647558386
GO:BP GO:0071310 cellular response to organic substance 8.07991091054697e-05 2776 121 40 0.330578512396694 0.0144092219020173
GO:BP GO:0071346 cellular response to interferon-gamma 8.958001144746e-05 175 139 10 0.0719424460431655 0.0571428571428571
GO:BP GO:0016192 vesicle-mediated transport 9.25342091981462e-05 2180 141 38 0.269503546099291 0.0174311926605505
GO:BP GO:0097190 apoptotic signaling pathway 9.33722439420486e-05 600 114 16 0.140350877192982 0.0266666666666667
GO:BP GO:0140352 export from cell 0.00010371368253704 1418 141 29 0.205673758865248 0.0204513399153738
GO:BP GO:0012501 programmed cell death 0.000105268244199665 2143 128 35 0.2734375 0.0163322445170322
GO:BP GO:0007166 cell surface receptor signaling pathway 0.000126936276909331 3210 120 43 0.358333333333333 0.0133956386292835
GO:BP GO:0008219 cell death 0.000169528299960401 2292 128 36 0.28125 0.0157068062827225
GO:BP GO:0042981 regulation of apoptotic process 0.000221711698715493 1549 128 28 0.21875 0.0180761781794706
GO:BP GO:0046903 secretion 0.000286605032741254 1501 141 29 0.205673758865248 0.0193204530313125
GO:BP GO:0043067 regulation of programmed cell death 0.000318274221504191 1582 128 28 0.21875 0.0176991150442478
GO:BP GO:0060333 interferon-gamma-mediated signaling pathway 0.000353230093570072 88 139 7 0.0503597122302158 0.0795454545454545
GO:BP GO:0072678 T cell migration 0.000353230093570072 67 119 6 0.0504201680672269 0.0895522388059701
GO:BP GO:0045087 innate immune response 0.000371378802705603 998 107 19 0.177570093457944 0.0190380761523046
GO:BP GO:0071356 cellular response to tumor necrosis factor 0.000402412183926975 306 120 11 0.0916666666666667 0.0359477124183007
GO:BP GO:0098542 defense response to other organism 0.000495993302805911 1218 107 21 0.196261682242991 0.0172413793103448
GO:BP GO:0052547 regulation of peptidase activity 0.000613137593987406 467 134 14 0.104477611940299 0.0299785867237687
GO:BP GO:0030162 regulation of proteolysis 0.000687014743174156 752 134 18 0.134328358208955 0.023936170212766
GO:BP GO:2000116 regulation of cysteine-type endopeptidase activity 0.000766094016554255 240 107 9 0.0841121495327103 0.0375
GO:BP GO:0034612 response to tumor necrosis factor 0.000766094016554255 331 120 11 0.0916666666666667 0.0332326283987915
GO:BP GO:0033209 tumor necrosis factor-mediated signaling pathway 0.000960980061326995 177 114 8 0.0701754385964912 0.0451977401129944
GO:BP GO:0010941 regulation of cell death 0.00112300260028344 1720 141 30 0.212765957446809 0.0174418604651163
GO:BP GO:0097193 intrinsic apoptotic signaling pathway 0.00113425563338111 294 52 7 0.134615384615385 0.0238095238095238
GO:BP GO:0052548 regulation of endopeptidase activity 0.0012190346705178 437 134 13 0.0970149253731343 0.0297482837528604
GO:BP GO:0046649 lymphocyte activation 0.00136234953964365 771 139 18 0.129496402877698 0.0233463035019455
GO:BP GO:0010033 response to organic substance 0.00136234953964365 3412 121 42 0.347107438016529 0.0123094958968347
GO:BP GO:0007165 signal transduction 0.00146076420389775 6309 132 69 0.522727272727273 0.0109367570137898
GO:BP GO:0043207 response to external biotic stimulus 0.00153981478596043 1594 71 18 0.253521126760563 0.0112923462986198
GO:BP GO:1902533 positive regulation of intracellular signal transduction 0.00153981478596043 1037 37 10 0.27027027027027 0.00964320154291225
GO:BP GO:0051707 response to other organism 0.00153981478596043 1592 71 18 0.253521126760563 0.0113065326633166
GO:BP GO:0019882 antigen processing and presentation 0.00157986826102724 234 95 8 0.0842105263157895 0.0341880341880342
GO:BP GO:0009607 response to biotic stimulus 0.00194691001840299 1626 71 18 0.253521126760563 0.011070110701107
GO:BP GO:0033627 cell adhesion mediated by integrin 0.00261618944134609 73 101 5 0.0495049504950495 0.0684931506849315
GO:BP GO:0002684 positive regulation of immune system process 0.00294168865303457 1065 139 21 0.151079136690647 0.0197183098591549
GO:BP GO:0007249 I-kappaB kinase/NF-kappaB signaling 0.00311320608209718 291 85 8 0.0941176470588235 0.0274914089347079
GO:BP GO:0048002 antigen processing and presentation of peptide antigen 0.00313198965193737 192 95 7 0.0736842105263158 0.0364583333333333
GO:BP GO:0002250 adaptive immune response 0.00356099618982378 689 139 16 0.115107913669065 0.02322206095791
GO:BP GO:0030335 positive regulation of cell migration 0.00356099618982378 567 134 14 0.104477611940299 0.0246913580246914
GO:BP GO:0043065 positive regulation of apoptotic process 0.00356099618982378 604 126 14 0.111111111111111 0.0231788079470199
GO:BP GO:0071901 negative regulation of protein serine/threonine kinase activity 0.00433496940839953 150 56 5 0.0892857142857143 0.0333333333333333
GO:BP GO:0009967 positive regulation of signal transduction 0.00451741846075222 1598 91 20 0.21978021978022 0.0125156445556946
GO:BP GO:0002456 T cell mediated immunity 0.00451741846075222 98 139 6 0.0431654676258993 0.0612244897959184
GO:BP GO:0043068 positive regulation of programmed cell death 0.00451741846075222 621 126 14 0.111111111111111 0.0225442834138486
GO:BP GO:0006508 proteolysis 0.00451741846075222 1836 138 29 0.210144927536232 0.0157952069716776
GO:BP GO:0048525 negative regulation of viral process 0.00454119263790583 94 91 5 0.0549450549450549 0.0531914893617021
GO:BP GO:0072676 lymphocyte migration 0.00479741403905451 117 119 6 0.0504201680672269 0.0512820512820513
GO:BP GO:0050896 response to stimulus 0.00479741403905451 9407 134 91 0.67910447761194 0.00967364728393749
GO:BP GO:0046718 viral entry into host cell 0.00479741403905451 141 141 7 0.049645390070922 0.049645390070922
GO:BP GO:0006954 inflammatory response 0.00479741403905451 794 113 15 0.132743362831858 0.0188916876574307
GO:BP GO:2000147 positive regulation of cell motility 0.0048061528630671 591 134 14 0.104477611940299 0.0236886632825719
GO:BP GO:0043122 regulation of I-kappaB kinase/NF-kappaB signaling 0.0050613994071829 251 138 9 0.0652173913043478 0.0358565737051793
GO:BP GO:0008630 intrinsic apoptotic signaling pathway in response to DNA damage 0.0050640402724834 103 46 4 0.0869565217391304 0.0388349514563107
GO:BP GO:0002833 positive regulation of response to biotic stimulus 0.00507244157254145 250 139 9 0.0647482014388489 0.036
GO:BP GO:0045088 regulation of innate immune response 0.00510625894289203 309 139 10 0.0719424460431655 0.0323624595469256
GO:BP GO:0023056 positive regulation of signaling 0.00514478213575493 1782 37 12 0.324324324324324 0.00673400673400673
GO:BP GO:0010952 positive regulation of peptidase activity 0.00522949024861655 205 134 8 0.0597014925373134 0.0390243902439024
GO:BP GO:0010977 negative regulation of neuron projection development 0.00552448211503399 140 104 6 0.0576923076923077 0.0428571428571429
GO:BP GO:0051272 positive regulation of cellular component movement 0.00552448211503399 604 134 14 0.104477611940299 0.0231788079470199
GO:BP GO:0040017 positive regulation of locomotion 0.00564734555912608 606 134 14 0.104477611940299 0.0231023102310231
GO:BP GO:0043281 regulation of cysteine-type endopeptidase activity involved in apoptotic process 0.00606056477177829 217 98 7 0.0714285714285714 0.032258064516129
GO:BP GO:0051716 cellular response to stimulus 0.00627250123975629 7781 133 78 0.586466165413534 0.0100244184552114
GO:BP GO:0032963 collagen metabolic process 0.00680004626964577 114 134 6 0.0447761194029851 0.0526315789473684
GO:BP GO:0044409 entry into host 0.00680004626964577 154 141 7 0.049645390070922 0.0454545454545455
GO:BP GO:0007155 cell adhesion 0.00738788835128265 1492 134 24 0.17910447761194 0.0160857908847185
GO:BP GO:0072659 protein localization to plasma membrane 0.00738788835128265 283 104 8 0.0769230769230769 0.0282685512367491
GO:BP GO:0007154 cell communication 0.00738788835128265 6829 132 70 0.53030303030303 0.0102504026943916
GO:BP GO:0051092 positive regulation of NF-kappaB transcription factor activity 0.00766065536457904 162 138 7 0.0507246376811594 0.0432098765432099
GO:BP GO:0072673 lamellipodium morphogenesis 0.00766065536457904 16 142 3 0.0211267605633803 0.1875
GO:BP GO:0022610 biological adhesion 0.00766065536457904 1499 134 24 0.17910447761194 0.0160106737825217
GO:BP GO:0070371 ERK1 and ERK2 cascade 0.00769360009244958 329 91 8 0.0879120879120879 0.0243161094224924
GO:BP GO:0002694 regulation of leukocyte activation 0.00774657278425314 610 139 14 0.100719424460432 0.0229508196721311
GO:BP GO:0001816 cytokine production 0.00778821029396183 844 139 17 0.122302158273381 0.0201421800947867
GO:BP GO:1902532 negative regulation of intracellular signal transduction 0.0079895086692065 549 56 8 0.142857142857143 0.0145719489981785
GO:BP GO:0071674 mononuclear cell migration 0.0079895086692065 191 119 7 0.0588235294117647 0.0366492146596859
GO:BP GO:0002479 antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent 0.008176379882193 75 139 5 0.0359712230215827 0.0666666666666667
GO:BP GO:0150076 neuroinflammatory response 0.00835553195474864 51 113 4 0.0353982300884956 0.0784313725490196
GO:BP GO:0031329 regulation of cellular catabolic process 0.00843029752908378 866 37 8 0.216216216216216 0.0092378752886836
GO:BP GO:0010942 positive regulation of cell death 0.00843029752908378 684 126 14 0.111111111111111 0.0204678362573099
GO:BP GO:0001913 T cell mediated cytotoxicity 0.00843029752908378 42 139 4 0.0287769784172662 0.0952380952380952
GO:BP GO:0002478 antigen processing and presentation of exogenous peptide antigen 0.00856679995879853 174 95 6 0.0631578947368421 0.0344827586206897
GO:BP GO:0002819 regulation of adaptive immune response 0.00856679995879853 167 139 7 0.0503597122302158 0.0419161676646707
GO:BP GO:2001056 positive regulation of cysteine-type endopeptidase activity 0.00856679995879853 154 107 6 0.0560747663551402 0.038961038961039
GO:BP GO:0050670 regulation of lymphocyte proliferation 0.00861923416165498 230 134 8 0.0597014925373134 0.0347826086956522
GO:BP GO:0001959 regulation of cytokine-mediated signaling pathway 0.00882564441396247 184 128 7 0.0546875 0.0380434782608696
GO:BP GO:0032944 regulation of mononuclear cell proliferation 0.00882564441396247 232 134 8 0.0597014925373134 0.0344827586206897
GO:BP GO:0042129 regulation of T cell proliferation 0.00882564441396247 176 134 7 0.0522388059701493 0.0397727272727273
GO:BP GO:0051649 establishment of localization in cell 0.00882564441396247 2813 141 38 0.269503546099291 0.0135087095627444
GO:BP GO:0002483 antigen processing and presentation of endogenous peptide antigen 0.0090211173385269 19 139 3 0.0215827338129496 0.157894736842105
GO:BP GO:0051641 cellular localization 0.0090211173385269 3541 142 45 0.316901408450704 0.0127082744987292
GO:BP GO:0045785 positive regulation of cell adhesion 0.0090211173385269 437 134 11 0.082089552238806 0.0251716247139588
GO:BP GO:0002520 immune system development 0.0090211173385269 1020 143 19 0.132867132867133 0.0186274509803922
GO:BP GO:0007229 integrin-mediated signaling pathway 0.0090211173385269 111 101 5 0.0495049504950495 0.045045045045045
GO:BP GO:0030574 collagen catabolic process 0.0090211173385269 47 134 4 0.0298507462686567 0.0851063829787234
GO:BP GO:0042590 antigen processing and presentation of exogenous peptide antigen via MHC class I 0.0090211173385269 80 139 5 0.0359712230215827 0.0625
GO:BP GO:0019884 antigen processing and presentation of exogenous antigen 0.0090211173385269 182 95 6 0.0631578947368421 0.032967032967033
GO:BP GO:0046596 regulation of viral entry into host cell 0.0090211173385269 43 60 3 0.05 0.0697674418604651
GO:BP GO:0048584 positive regulation of response to stimulus 0.0090211173385269 2344 91 24 0.263736263736264 0.0102389078498294
GO:BP GO:0048585 negative regulation of response to stimulus 0.0090211173385269 1733 48 13 0.270833333333333 0.00750144258511252
GO:BP GO:0023052 signaling 0.0090211173385269 6810 132 69 0.522727272727273 0.0101321585903084
GO:BP GO:0043066 negative regulation of apoptotic process 0.0090211173385269 921 98 14 0.142857142857143 0.0152008686210641
GO:BP GO:0030097 hemopoiesis 0.0090211173385269 928 143 18 0.125874125874126 0.0193965517241379
GO:BP GO:0050792 regulation of viral process 0.0090211173385269 192 91 6 0.0659340659340659 0.03125
GO:BP GO:0010647 positive regulation of cell communication 0.0090211173385269 1777 91 20 0.21978021978022 0.0112549240292628
GO:BP GO:0009605 response to external stimulus 0.0090211173385269 2944 132 37 0.28030303030303 0.0125679347826087
GO:BP GO:0002831 regulation of response to biotic stimulus 0.0090211173385269 415 139 11 0.079136690647482 0.0265060240963855
GO:BP GO:0050900 leukocyte migration 0.0090211173385269 511 132 12 0.0909090909090909 0.0234833659491194
GO:BP GO:0060548 negative regulation of cell death 0.0090211173385269 1038 141 19 0.134751773049645 0.0183044315992293
GO:BP GO:2001242 regulation of intrinsic apoptotic signaling pathway 0.0090211173385269 167 37 4 0.108108108108108 0.0239520958083832
GO:BP GO:1903039 positive regulation of leukocyte cell-cell adhesion 0.0090211173385269 241 134 8 0.0597014925373134 0.033195020746888
GO:BP GO:0045639 positive regulation of myeloid cell differentiation 0.00906516222060847 103 112 5 0.0446428571428571 0.0485436893203883
GO:BP GO:0030036 actin cytoskeleton organization 0.00919306393504187 709 142 15 0.105633802816901 0.0211565585331453
GO:BP GO:0001817 regulation of cytokine production 0.00927810825594542 806 139 16 0.115107913669065 0.0198511166253102
GO:BP GO:0052126 movement in host environment 0.00942859932319134 177 141 7 0.049645390070922 0.0395480225988701
GO:BP GO:0007159 leukocyte cell-cell adhesion 0.00942859932319134 375 134 10 0.0746268656716418 0.0266666666666667
GO:BP GO:2001233 regulation of apoptotic signaling pathway 0.00942859932319134 363 114 9 0.0789473684210526 0.0247933884297521
GO:BP GO:0043280 positive regulation of cysteine-type endopeptidase activity involved in apoptotic process 0.00942859932319134 138 85 5 0.0588235294117647 0.036231884057971
GO:BP GO:0010950 positive regulation of endopeptidase activity 0.00946903379827578 187 134 7 0.0522388059701493 0.0374331550802139
GO:BP GO:0002460 adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains 0.00964383846706977 363 139 10 0.0719424460431655 0.0275482093663912
GO:BP GO:0060759 regulation of response to cytokine stimulus 0.00970189317838148 197 128 7 0.0546875 0.0355329949238579
GO:BP GO:0045862 positive regulation of proteolysis 0.00978034288259817 378 134 10 0.0746268656716418 0.0264550264550265
GO:BP GO:0050865 regulation of cell activation 0.00984910756066395 655 139 14 0.100719424460432 0.0213740458015267
GO:BP GO:0097191 extrinsic apoptotic signaling pathway 0.00995153192423887 223 114 7 0.0614035087719298 0.031390134529148
GO:BP GO:0043069 negative regulation of programmed cell death 0.0100892143174404 943 98 14 0.142857142857143 0.0148462354188759
GO:BP GO:0043123 positive regulation of I-kappaB kinase/NF-kappaB signaling 0.0101764672106487 185 138 7 0.0507246376811594 0.0378378378378378
GO:BP GO:0043903 regulation of biological process involved in symbiotic interaction 0.0102798496246055 203 91 6 0.0659340659340659 0.0295566502463054
GO:BP GO:0051336 regulation of hydrolase activity 0.0102798496246055 1321 141 22 0.156028368794326 0.0166540499621499
GO:BP GO:0070663 regulation of leukocyte proliferation 0.0103796224243684 251 134 8 0.0597014925373134 0.0318725099601594
GO:BP GO:0010712 regulation of collagen metabolic process 0.0106413574920918 52 134 4 0.0298507462686567 0.0769230769230769
GO:BP GO:0052372 modulation by symbiont of entry into host 0.0106413574920918 50 60 3 0.05 0.06
GO:BP GO:0032103 positive regulation of response to external stimulus 0.0106413574920918 513 139 12 0.0863309352517986 0.0233918128654971
GO:BP GO:0048534 hematopoietic or lymphoid organ development 0.0106413574920918 966 143 18 0.125874125874126 0.0186335403726708
GO:BP GO:0030029 actin filament-based process 0.0106413574920918 808 142 16 0.112676056338028 0.0198019801980198
GO:BP GO:0051607 defense response to virus 0.0107770119552748 267 128 8 0.0625 0.0299625468164794
GO:BP GO:0140546 defense response to symbiont 0.0107770119552748 267 128 8 0.0625 0.0299625468164794
GO:BP GO:0097435 supramolecular fiber organization 0.0111553721910977 734 142 15 0.105633802816901 0.0204359673024523
GO:BP GO:0051249 regulation of lymphocyte activation 0.0111553721910977 518 139 12 0.0863309352517986 0.0231660231660232
GO:BP GO:0097066 response to thyroid hormone 0.0114741507276258 26 121 3 0.0247933884297521 0.115384615384615
GO:BP GO:0048519 negative regulation of biological process 0.0115931116592274 5757 71 36 0.507042253521127 0.00625325690463783
GO:BP GO:0051345 positive regulation of hydrolase activity 0.0115931116592274 783 134 15 0.111940298507463 0.0191570881226054
GO:BP GO:0071677 positive regulation of mononuclear cell migration 0.0117300094294396 65 112 4 0.0357142857142857 0.0615384615384615
GO:BP GO:0035456 response to interferon-beta 0.0120557276497565 30 107 3 0.0280373831775701 0.1
GO:BP GO:1990778 protein localization to cell periphery 0.0121925020595777 338 104 8 0.0769230769230769 0.0236686390532544
GO:BP GO:0007015 actin filament organization 0.0127128683337818 445 142 11 0.0774647887323944 0.0247191011235955
GO:BP GO:0031345 negative regulation of cell projection organization 0.0127128683337818 189 104 6 0.0576923076923077 0.0317460317460317
GO:BP GO:0002521 leukocyte differentiation 0.0129820329107785 550 134 12 0.0895522388059701 0.0218181818181818
GO:BP GO:0042098 T cell proliferation 0.0134798460956828 205 134 7 0.0522388059701493 0.0341463414634146
GO:BP GO:0042221 response to chemical 0.0134798460956828 4781 142 55 0.387323943661972 0.0115038694833717
GO:BP GO:0031638 zymogen activation 0.0138660020263518 58 134 4 0.0298507462686567 0.0689655172413793
GO:BP GO:0050790 regulation of catalytic activity 0.0144119327099563 2545 141 34 0.24113475177305 0.0133595284872299
GO:BP GO:0070372 regulation of ERK1 and ERK2 cascade 0.0144119327099563 309 91 7 0.0769230769230769 0.0226537216828479
GO:BP GO:0002230 positive regulation of defense response to virus by host 0.0146010767311315 33 107 3 0.0280373831775701 0.0909090909090909
GO:BP GO:0034109 homotypic cell-cell adhesion 0.0146010767311315 87 91 4 0.043956043956044 0.0459770114942529
GO:BP GO:0098609 cell-cell adhesion 0.0146010767311315 894 33 7 0.212121212121212 0.00782997762863535
GO:BP GO:0009894 regulation of catabolic process 0.0146010767311315 1033 37 8 0.216216216216216 0.00774443368828654
GO:BP GO:0031647 regulation of protein stability 0.0146155306077962 300 122 8 0.0655737704918033 0.0266666666666667
GO:BP GO:0001933 negative regulation of protein phosphorylation 0.0146270367846623 373 56 6 0.107142857142857 0.0160857908847185
GO:BP GO:0002474 antigen processing and presentation of peptide antigen via MHC class I 0.0146270367846623 99 139 5 0.0359712230215827 0.0505050505050505
GO:BP GO:0006950 response to stress 0.0146270367846623 4170 120 43 0.358333333333333 0.0103117505995204
GO:BP GO:0019883 antigen processing and presentation of endogenous antigen 0.014747362674757 26 139 3 0.0215827338129496 0.115384615384615
GO:BP GO:0042110 T cell activation 0.0149823988431307 489 134 11 0.082089552238806 0.0224948875255624
GO:BP GO:1903900 regulation of viral life cycle 0.0151120998497142 153 91 5 0.0549450549450549 0.0326797385620915
GO:BP GO:0006469 negative regulation of protein kinase activity 0.0151839175409934 251 56 5 0.0892857142857143 0.0199203187250996
GO:BP GO:0031589 cell-substrate adhesion 0.0153725783758589 367 126 9 0.0714285714285714 0.0245231607629428
GO:BP GO:2001243 negative regulation of intrinsic apoptotic signaling pathway 0.0156773441413268 100 37 3 0.0810810810810811 0.03
GO:BP GO:0010714 positive regulation of collagen metabolic process 0.0159060598904118 28 134 3 0.0223880597014925 0.107142857142857
GO:BP GO:0009615 response to virus 0.0159060598904118 364 128 9 0.0703125 0.0247252747252747
GO:BP GO:1903078 positive regulation of protein localization to plasma membrane 0.0159579201414451 63 132 4 0.0303030303030303 0.0634920634920635
GO:BP GO:0048583 regulation of response to stimulus 0.0161169637815753 4278 142 50 0.352112676056338 0.0116877045348294
GO:BP GO:0050870 positive regulation of T cell activation 0.0169235983371917 219 134 7 0.0522388059701493 0.0319634703196347
GO:BP GO:0022409 positive regulation of cell-cell adhesion 0.0171869022114374 284 134 8 0.0597014925373134 0.028169014084507
GO:BP GO:0002696 positive regulation of leukocyte activation 0.0177876063650793 412 139 10 0.0719424460431655 0.0242718446601942
GO:BP GO:2001235 positive regulation of apoptotic signaling pathway 0.0178919026433425 129 114 5 0.043859649122807 0.0387596899224806
GO:BP GO:0048523 negative regulation of cellular process 0.0182302155536126 5139 38 20 0.526315789473684 0.00389180774469741
GO:BP GO:2000404 regulation of T cell migration 0.0183393689188204 44 91 3 0.032967032967033 0.0681818181818182
GO:BP GO:0045089 positive regulation of innate immune response 0.0183401995029212 216 139 7 0.0503597122302158 0.0324074074074074
GO:BP GO:0032269 negative regulation of cellular protein metabolic process 0.0185951397211903 1082 56 10 0.178571428571429 0.00924214417744917
GO:BP GO:0071222 cellular response to lipopolysaccharide 0.0185951397211903 200 113 6 0.0530973451327434 0.03
GO:BP GO:0065008 regulation of biological quality 0.0185951397211903 4131 34 16 0.470588235294118 0.00387315419995159
GO:BP GO:0032101 regulation of response to external stimulus 0.0185951397211903 1051 142 18 0.126760563380282 0.0171265461465271
GO:BP GO:0050867 positive regulation of cell activation 0.0185951397211903 424 139 10 0.0719424460431655 0.0235849056603774
GO:BP GO:0032943 mononuclear cell proliferation 0.0185951397211903 297 134 8 0.0597014925373134 0.0269360269360269
GO:BP GO:0051248 negative regulation of protein metabolic process 0.0185951397211903 1151 100 15 0.15 0.0130321459600348
GO:BP GO:0023051 regulation of signaling 0.0185951397211903 3578 56 21 0.375 0.00586920067076579
GO:BP GO:0033673 negative regulation of kinase activity 0.0185951397211903 275 56 5 0.0892857142857143 0.0181818181818182
GO:BP GO:0002687 positive regulation of leukocyte migration 0.0185951397211903 137 112 5 0.0446428571428571 0.0364963503649635
GO:BP GO:0046651 lymphocyte proliferation 0.0185951397211903 294 134 8 0.0597014925373134 0.0272108843537415
GO:BP GO:0002449 lymphocyte mediated immunity 0.0185951397211903 354 139 9 0.0647482014388489 0.0254237288135593
GO:BP GO:0002576 platelet degranulation 0.0185951397211903 126 71 4 0.0563380281690141 0.0317460317460317
GO:BP GO:0120035 regulation of plasma membrane bounded cell projection organization 0.0185951397211903 638 142 13 0.0915492957746479 0.0203761755485893
GO:BP GO:0043112 receptor metabolic process 0.0186095872224119 174 89 5 0.0561797752808989 0.028735632183908
GO:BP GO:1904377 positive regulation of protein localization to cell periphery 0.0188329813765506 70 132 4 0.0303030303030303 0.0571428571428571
GO:BP GO:0051701 biological process involved in interaction with host 0.0191567622510681 221 141 7 0.049645390070922 0.0316742081447964
GO:BP GO:0044093 positive regulation of molecular function 0.0194300853278348 1771 138 25 0.181159420289855 0.0141163184641446
GO:BP GO:0019058 viral life cycle 0.0194300853278348 353 141 9 0.0638297872340425 0.0254957507082153
GO:BP GO:0042326 negative regulation of phosphorylation 0.019688903351623 420 56 6 0.107142857142857 0.0142857142857143
GO:BP GO:0016485 protein processing 0.0197713788578732 235 134 7 0.0522388059701493 0.0297872340425532
GO:BP GO:0009057 macromolecule catabolic process 0.0199352780759799 1468 122 20 0.163934426229508 0.0136239782016349
GO:BP GO:0042102 positive regulation of T cell proliferation 0.0199352780759799 104 91 4 0.043956043956044 0.0384615384615385
GO:BP GO:0031349 positive regulation of defense response 0.0204981784875782 362 139 9 0.0647482014388489 0.0248618784530387
GO:BP GO:0031400 negative regulation of protein modification process 0.0205139822548731 578 56 7 0.125 0.0121107266435986
GO:BP GO:0031344 regulation of cell projection organization 0.0207167459262582 656 142 13 0.0915492957746479 0.0198170731707317
GO:BP GO:0051604 protein maturation 0.0208675961391313 306 134 8 0.0597014925373134 0.0261437908496732
GO:BP GO:0051251 positive regulation of lymphocyte activation 0.0210722325886049 365 139 9 0.0647482014388489 0.0246575342465753
GO:BP GO:0050691 regulation of defense response to virus by host 0.0213305364608843 43 107 3 0.0280373831775701 0.0697674418604651
GO:BP GO:0006909 phagocytosis 0.0216355720480254 387 132 9 0.0681818181818182 0.0232558139534884
GO:BP GO:0006968 cellular defense response 0.0224812290923447 53 89 3 0.0337078651685393 0.0566037735849057
GO:BP GO:0071219 cellular response to molecule of bacterial origin 0.0224812290923447 214 113 6 0.0530973451327434 0.0280373831775701
GO:BP GO:0048522 positive regulation of cellular process 0.0227538794849182 5757 38 21 0.552631578947368 0.00364773319437207
GO:BP GO:0030163 protein catabolic process 0.0228122475175542 974 122 15 0.122950819672131 0.0154004106776181
GO:BP GO:0032479 regulation of type I interferon production 0.0228381127626996 130 128 5 0.0390625 0.0384615384615385
GO:BP GO:0033628 regulation of cell adhesion mediated by integrin 0.0232218215220482 48 100 3 0.03 0.0625
GO:BP GO:0065009 regulation of molecular function 0.0232417241222042 3221 141 39 0.276595744680851 0.0121080409810618
GO:BP GO:0032606 type I interferon production 0.0232417241222042 131 128 5 0.0390625 0.0381679389312977
GO:BP GO:0032956 regulation of actin cytoskeleton organization 0.0232417241222042 366 142 9 0.0633802816901408 0.0245901639344262
GO:BP GO:0043085 positive regulation of catalytic activity 0.0234982873378301 1418 138 21 0.152173913043478 0.0148095909732017
GO:BP GO:0045071 negative regulation of viral genome replication 0.0241096400097273 54 91 3 0.032967032967033 0.0555555555555556
GO:BP GO:0008284 positive regulation of cell population proliferation 0.024852542977683 982 99 13 0.131313131313131 0.0132382892057026
GO:BP GO:0042113 B cell activation 0.024852542977683 330 130 8 0.0615384615384615 0.0242424242424242
GO:BP GO:0051348 negative regulation of transferase activity 0.0248630508077886 310 56 5 0.0892857142857143 0.0161290322580645
GO:BP GO:0045637 regulation of myeloid cell differentiation 0.0249247509841609 263 128 7 0.0546875 0.026615969581749
GO:BP GO:1905477 positive regulation of protein localization to membrane 0.0253241020310808 131 132 5 0.0378787878787879 0.0381679389312977
GO:BP GO:0031641 regulation of myelination 0.0257012538799775 45 113 3 0.0265486725663717 0.0666666666666667
GO:BP GO:0010975 regulation of neuron projection development 0.0260286957039541 451 141 10 0.0709219858156028 0.0221729490022173
GO:BP GO:0070661 leukocyte proliferation 0.0267349802804697 325 134 8 0.0597014925373134 0.0246153846153846
GO:BP GO:0031347 regulation of defense response 0.0275133373650624 704 139 13 0.0935251798561151 0.0184659090909091
GO:BP GO:0070266 necroptotic process 0.0275957437887802 46 114 3 0.0263157894736842 0.0652173913043478
GO:BP GO:0022604 regulation of cell morphogenesis 0.0276259471662101 309 142 8 0.0563380281690141 0.0258899676375405
GO:BP GO:1901653 cellular response to peptide 0.0276259471662101 408 85 7 0.0823529411764706 0.017156862745098
GO:BP GO:1902531 regulation of intracellular signal transduction 0.027697291580076 1842 37 10 0.27027027027027 0.00542888165038002
GO:BP GO:1900026 positive regulation of substrate adhesion-dependent cell spreading 0.0277681964295017 42 126 3 0.0238095238095238 0.0714285714285714
GO:BP GO:0051493 regulation of cytoskeleton organization 0.0279285702671097 531 142 11 0.0774647887323944 0.0207156308851224
GO:BP GO:0150077 regulation of neuroinflammatory response 0.0280126924346667 47 113 3 0.0265486725663717 0.0638297872340425
GO:BP GO:0043086 negative regulation of catalytic activity 0.028050117721212 851 42 7 0.166666666666667 0.0082256169212691
GO:BP GO:1903037 regulation of leukocyte cell-cell adhesion 0.0281398702148809 338 33 4 0.121212121212121 0.0118343195266272
GO:BP GO:0050764 regulation of phagocytosis 0.0281439677693153 98 112 4 0.0357142857142857 0.0408163265306122
GO:BP GO:0032088 negative regulation of NF-kappaB transcription factor activity 0.0283643248022682 97 114 4 0.0350877192982456 0.0412371134020619
GO:BP GO:0002695 negative regulation of leukocyte activation 0.0283643248022682 188 139 6 0.0431654676258993 0.0319148936170213
GO:BP GO:2001236 regulation of extrinsic apoptotic signaling pathway 0.028365590698347 159 114 5 0.043859649122807 0.0314465408805031
GO:BP GO:0048518 positive regulation of biological process 0.0288906941351959 6363 38 22 0.578947368421053 0.00345748860600346
GO:BP GO:0010646 regulation of cell communication 0.0288997225405159 3543 56 20 0.357142857142857 0.00564493367202935
GO:BP GO:0010506 regulation of autophagy 0.029094803376046 336 34 4 0.117647058823529 0.0119047619047619
GO:BP GO:0050863 regulation of T cell activation 0.02992699591546 337 134 8 0.0597014925373134 0.0237388724035608
GO:BP GO:0016601 Rac protein signal transduction 0.0302933117849219 40 141 3 0.0212765957446809 0.075
GO:BP GO:0080135 regulation of cellular response to stress 0.0303472170261957 725 38 6 0.157894736842105 0.00827586206896552
GO:BP GO:0071216 cellular response to biotic stimulus 0.030568158661208 238 113 6 0.0530973451327434 0.0252100840336134
GO:BP GO:0048678 response to axon injury 0.0306354569632584 80 71 3 0.0422535211267606 0.0375
GO:BP GO:0009617 response to bacterium 0.0306354569632584 743 120 12 0.1 0.0161507402422611
GO:BP GO:1901701 cellular response to oxygen-containing compound 0.0309513124645101 1227 113 16 0.141592920353982 0.013039934800326
GO:BP GO:0010634 positive regulation of epithelial cell migration 0.0309513124645101 181 104 5 0.0480769230769231 0.0276243093922652
GO:BP GO:2000401 regulation of lymphocyte migration 0.0309754699742846 63 91 3 0.032967032967033 0.0476190476190476
GO:BP GO:0044092 negative regulation of molecular function 0.0312962853784633 1219 114 16 0.140350877192982 0.0131255127153404
GO:BP GO:0043525 positive regulation of neuron apoptotic process 0.0321521516014376 59 99 3 0.0303030303030303 0.0508474576271186
GO:BP GO:0002685 regulation of leukocyte migration 0.0343365707832657 211 132 6 0.0454545454545455 0.028436018957346
GO:BP GO:0043113 receptor clustering 0.0343710091944159 54 112 3 0.0267857142857143 0.0555555555555556
GO:BP GO:0043410 positive regulation of MAPK cascade 0.0343710091944159 539 37 5 0.135135135135135 0.00927643784786642
GO:BP GO:0070374 positive regulation of ERK1 and ERK2 cascade 0.03454536834776 215 91 5 0.0549450549450549 0.0232558139534884
GO:BP GO:0016477 cell migration 0.0349967603030313 1649 142 23 0.161971830985915 0.0139478471801092
GO:BP GO:0051091 positive regulation of DNA-binding transcription factor activity 0.0351508174566551 270 138 7 0.0507246376811594 0.0259259259259259
GO:BP GO:1903131 mononuclear cell differentiation 0.0353299437297273 430 134 9 0.0671641791044776 0.0209302325581395
GO:BP GO:0032970 regulation of actin filament-based process 0.0354293562505319 406 142 9 0.0633802816901408 0.0221674876847291
GO:BP GO:0097300 programmed necrotic cell death 0.0354293562505319 54 114 3 0.0263157894736842 0.0555555555555556
GO:BP GO:0032869 cellular response to insulin stimulus 0.0362595653182941 235 85 5 0.0588235294117647 0.0212765957446809
GO:BP GO:0034113 heterotypic cell-cell adhesion 0.0364413340659832 62 101 3 0.0297029702970297 0.0483870967741935
GO:BP GO:1902903 regulation of supramolecular fiber organization 0.037217936728704 387 33 4 0.121212121212121 0.0103359173126615
GO:BP GO:0030334 regulation of cell migration 0.0373024627694201 999 142 16 0.112676056338028 0.016016016016016
GO:BP GO:0071675 regulation of mononuclear cell migration 0.0379897954600528 113 112 4 0.0357142857142857 0.0353982300884956
GO:BP GO:0080134 regulation of response to stress 0.0379897954600528 1443 91 15 0.164835164835165 0.0103950103950104
GO:BP GO:0030099 myeloid cell differentiation 0.0380913932695834 428 48 5 0.104166666666667 0.0116822429906542
GO:BP GO:0009968 negative regulation of signal transduction 0.0387304841383631 1364 37 8 0.216216216216216 0.00586510263929619
GO:BP GO:0009966 regulation of signal transduction 0.0388384059215712 3165 56 18 0.321428571428571 0.00568720379146919
GO:BP GO:0050671 positive regulation of lymphocyte proliferation 0.0392115088439131 141 91 4 0.043956043956044 0.0283687943262411
GO:BP GO:0032946 positive regulation of mononuclear cell proliferation 0.0396922256257913 142 91 4 0.043956043956044 0.028169014084507
GO:BP GO:0097581 lamellipodium organization 0.0396922256257913 91 142 4 0.028169014084507 0.043956043956044
GO:BP GO:0044248 cellular catabolic process 0.0397504903243572 2347 37 11 0.297297297297297 0.00468683425649766
GO:BP GO:1903036 positive regulation of response to wounding 0.0399131049958677 74 89 3 0.0337078651685393 0.0405405405405405
GO:BP GO:0050866 negative regulation of cell activation 0.0399535473230922 211 139 6 0.0431654676258993 0.028436018957346
GO:BP GO:0048731 system development 0.0399954873110054 5052 12 8 0.666666666666667 0.00158353127474268
GO:BP GO:0002763 positive regulation of myeloid leukocyte differentiation 0.0399954873110054 59 112 3 0.0267857142857143 0.0508474576271186
GO:BP GO:0009892 negative regulation of metabolic process 0.0410367243717186 3479 48 17 0.354166666666667 0.00488646162690428
GO:BP GO:0030030 cell projection organization 0.0414029809738505 1609 26 7 0.269230769230769 0.00435052827843381
GO:BP GO:0030155 regulation of cell adhesion 0.041694989189971 748 143 13 0.0909090909090909 0.017379679144385
GO:BP GO:0009056 catabolic process 0.0417527974050172 2744 37 12 0.324324324324324 0.0043731778425656
GO:BP GO:0010563 negative regulation of phosphorus metabolic process 0.0417527974050172 544 56 6 0.107142857142857 0.0110294117647059
GO:BP GO:0032760 positive regulation of tumor necrosis factor production 0.0417527974050172 88 78 3 0.0384615384615385 0.0340909090909091
GO:BP GO:0045936 negative regulation of phosphate metabolic process 0.0417527974050172 543 56 6 0.107142857142857 0.0110497237569061
GO:BP GO:0050766 positive regulation of phagocytosis 0.0417527974050172 67 102 3 0.0294117647058824 0.0447761194029851
GO:BP GO:0043433 negative regulation of DNA-binding transcription factor activity 0.0417527974050172 187 114 5 0.043859649122807 0.0267379679144385
GO:BP GO:0042306 regulation of protein import into nucleus 0.0420192049748938 62 112 3 0.0267857142857143 0.0483870967741935
GO:BP GO:0030098 lymphocyte differentiation 0.0430341249923735 376 134 8 0.0597014925373134 0.0212765957446809
GO:BP GO:0070997 neuron death 0.0432196774168642 365 38 4 0.105263157894737 0.010958904109589
GO:BP GO:0045123 cellular extravasation 0.043485445784432 70 101 3 0.0297029702970297 0.0428571428571429
GO:BP GO:0040011 locomotion 0.0435338571339685 2028 134 25 0.186567164179104 0.01232741617357
GO:BP GO:0034446 substrate adhesion-dependent cell spreading 0.0435394709344473 109 126 4 0.0317460317460317 0.036697247706422
GO:BP GO:0051250 negative regulation of lymphocyte activation 0.0435394709344473 156 139 5 0.0359712230215827 0.032051282051282
GO:BP GO:1903557 positive regulation of tumor necrosis factor superfamily cytokine production 0.0435777421730362 91 78 3 0.0384615384615385 0.032967032967033
GO:BP GO:0034655 nucleobase-containing compound catabolic process 0.0435777421730362 567 25 4 0.16 0.00705467372134039
GO:BP GO:0006301 postreplication repair 0.0439076459196404 52 138 3 0.0217391304347826 0.0576923076923077
GO:BP GO:0035556 intracellular signal transduction 0.0439076459196404 2772 141 33 0.234042553191489 0.0119047619047619
GO:BP GO:0050777 negative regulation of immune response 0.0439076459196404 157 139 5 0.0359712230215827 0.0318471337579618
GO:BP GO:1903076 regulation of protein localization to plasma membrane 0.0439730166510065 105 132 4 0.0303030303030303 0.0380952380952381
GO:BP GO:0010803 regulation of tumor necrosis factor-mediated signaling pathway 0.0439731875727089 63 114 3 0.0263157894736842 0.0476190476190476
GO:BP GO:0006749 glutathione metabolic process 0.0446194517784538 63 115 3 0.0260869565217391 0.0476190476190476
GO:BP GO:0030100 regulation of endocytosis 0.0447440534668873 212 104 5 0.0480769230769231 0.0235849056603774
GO:BP GO:1904589 regulation of protein import 0.044994374893681 65 112 3 0.0267857142857143 0.0461538461538462
GO:BP GO:0000165 MAPK cascade 0.0450715676062092 935 56 8 0.142857142857143 0.00855614973262032
GO:BP GO:0007010 cytoskeleton organization 0.0450715676062092 1423 142 20 0.140845070422535 0.0140548137737175
GO:BP GO:1900024 regulation of substrate adhesion-dependent cell spreading 0.0450715676062092 58 126 3 0.0238095238095238 0.0517241379310345
GO:BP GO:0051246 regulation of protein metabolic process 0.0451341258146921 2704 113 27 0.238938053097345 0.00998520710059172
GO:BP GO:0070665 positive regulation of leukocyte proliferation 0.0451341258146921 155 91 4 0.043956043956044 0.0258064516129032
GO:BP GO:0045807 positive regulation of endocytosis 0.0464364957898181 101 74 3 0.0405405405405405 0.0297029702970297
GO:BP GO:0051090 regulation of DNA-binding transcription factor activity 0.0464364957898181 456 114 8 0.0701754385964912 0.0175438596491228
GO:BP GO:0001906 cell killing 0.0464364957898181 175 82 4 0.0487804878048781 0.0228571428571429
GO:BP GO:0072657 protein localization to membrane 0.0464364957898181 665 112 10 0.0892857142857143 0.0150375939849624
GO:BP GO:0001819 positive regulation of cytokine production 0.0464364957898181 452 139 9 0.0647482014388489 0.0199115044247788
GO:BP GO:0022407 regulation of cell-cell adhesion 0.0464933409323835 445 33 4 0.121212121212121 0.00898876404494382
GO:BP GO:0042775 mitochondrial ATP synthesis coupled electron transport 0.0464933409323835 99 76 3 0.0394736842105263 0.0303030303030303
GO:BP GO:0010648 negative regulation of cell communication 0.0465246902035411 1468 37 8 0.216216216216216 0.00544959128065395
GO:BP GO:0042773 ATP synthesis coupled electron transport 0.0465246902035411 100 76 3 0.0394736842105263 0.03
GO:BP GO:0023057 negative regulation of signaling 0.0465246902035411 1471 37 8 0.216216216216216 0.00543847722637661
GO:BP GO:0050688 regulation of defense response to virus 0.0465246902035411 71 107 3 0.0280373831775701 0.0422535211267606
GO:BP GO:0045069 regulation of viral genome replication 0.0470239940513026 84 91 3 0.032967032967033 0.0357142857142857
GO:BP GO:0046700 heterocycle catabolic process 0.0471370453970468 602 25 4 0.16 0.00664451827242525
GO:BP GO:0051128 regulation of cellular component organization 0.0471370453970468 2412 38 11 0.289473684210526 0.00456053067993367
GO:BP GO:2000145 regulation of cell motility 0.0481866010374646 1061 142 16 0.112676056338028 0.0150801131008483
GO:BP GO:0010951 negative regulation of endopeptidase activity 0.0481866010374646 253 31 3 0.0967741935483871 0.0118577075098814
GO:BP GO:0044270 cellular nitrogen compound catabolic process 0.0481866010374646 608 25 4 0.16 0.00657894736842105
GO:BP GO:0070265 necrotic cell death 0.0481866010374646 68 114 3 0.0263157894736842 0.0441176470588235
GO:BP GO:2001234 negative regulation of apoptotic signaling pathway 0.0484905175341699 236 98 5 0.0510204081632653 0.0211864406779661
GO:BP GO:0006919 activation of cysteine-type endopeptidase activity involved in apoptotic process 0.0487138094875369 92 85 3 0.0352941176470588 0.0326086956521739
GO:BP GO:0001818 negative regulation of cytokine production 0.0487138094875369 381 139 8 0.0575539568345324 0.020997375328084
GO:BP GO:0001909 leukocyte mediated cytotoxicity 0.0487630646099818 107 139 4 0.0287769784172662 0.0373831775700935
GO:BP GO:0051129 negative regulation of cellular component organization 0.0489324325736787 759 11 3 0.272727272727273 0.00395256916996047
GO:BP GO:0070098 chemokine-mediated signaling pathway 0.0492743827911473 87 91 3 0.032967032967033 0.0344827586206897
GO:BP GO:1901565 organonitrogen compound catabolic process 0.0492743827911473 1358 122 17 0.139344262295082 0.0125184094256259
GO:BP GO:1903034 regulation of response to wounding 0.0494490754216648 169 89 4 0.0449438202247191 0.0236686390532544
GO:BP GO:0031529 ruffle organization 0.0494490754216648 56 142 3 0.0211267605633803 0.0535714285714286
GO:BP GO:0014812 muscle cell migration 0.049531574034709 106 142 4 0.028169014084507 0.0377358490566038
GO:BP GO:0001525 angiogenesis 0.0499735714005053 617 54 6 0.111111111111111 0.00972447325769854
GO:CC GO:0031982 vesicle 4.70111916817679e-13 4055 143 74 0.517482517482518 0.018249075215783
GO:CC GO:0070062 extracellular exosome 1.34826514006277e-09 2176 142 47 0.330985915492958 0.0215992647058824
GO:CC GO:0097708 intracellular vesicle 2.09865573355504e-09 2428 143 49 0.342657342657343 0.0201812191103789
GO:CC GO:0043230 extracellular organelle 2.09865573355504e-09 2263 142 47 0.330985915492958 0.0207688908528502
GO:CC GO:1903561 extracellular vesicle 2.09865573355504e-09 2261 142 47 0.330985915492958 0.0207872622733304
GO:CC GO:0031410 cytoplasmic vesicle 2.09865573355504e-09 2424 143 49 0.342657342657343 0.0202145214521452
GO:CC GO:0005615 extracellular space 6.7281525179098e-07 3594 11 11 1 0.00306065664997218
GO:CC GO:0030141 secretory granule 8.88874752130578e-07 851 141 24 0.170212765957447 0.0282021151586369
GO:CC GO:0001726 ruffle 2.47573109377823e-06 179 104 10 0.0961538461538462 0.0558659217877095
GO:CC GO:0031983 vesicle lumen 4.70832667314943e-06 326 141 14 0.099290780141844 0.0429447852760736
GO:CC GO:0034774 secretory granule lumen 4.70832667314943e-06 320 141 14 0.099290780141844 0.04375
GO:CC GO:0005576 extracellular region 4.70832667314943e-06 4567 11 11 1 0.00240858331508649
GO:CC GO:0060205 cytoplasmic vesicle lumen 4.70832667314943e-06 324 141 14 0.099290780141844 0.0432098765432099
GO:CC GO:0099503 secretory vesicle 4.70832667314943e-06 1020 141 25 0.177304964539007 0.0245098039215686
GO:CC GO:0031252 cell leading edge 1.85422120426624e-05 422 142 15 0.105633802816901 0.0355450236966825
GO:CC GO:0071944 cell periphery 1.9465243074395e-05 6169 106 59 0.556603773584906 0.00956394877613876
GO:CC GO:0005768 endosome 3.27909163423325e-05 987 143 23 0.160839160839161 0.0233029381965552
GO:CC GO:0097169 AIM2 inflammasome complex 3.65977164601708e-05 5 107 3 0.0280373831775701 0.6
GO:CC GO:0005764 lysosome 3.65977164601708e-05 712 143 19 0.132867132867133 0.026685393258427
GO:CC GO:0000323 lytic vacuole 3.65977164601708e-05 712 143 19 0.132867132867133 0.026685393258427
GO:CC GO:0005773 vacuole 5.93975152057884e-05 810 143 20 0.13986013986014 0.0246913580246914
GO:CC GO:0005886 plasma membrane 7.93707874547838e-05 5681 106 54 0.509433962264151 0.00950536877310333
GO:CC GO:0005766 primary lysosome 7.93707874547838e-05 154 82 7 0.0853658536585366 0.0454545454545455
GO:CC GO:0042470 melanosome 7.93707874547838e-05 105 121 7 0.0578512396694215 0.0666666666666667
GO:CC GO:0042582 azurophil granule 7.93707874547838e-05 154 82 7 0.0853658536585366 0.0454545454545455
GO:CC GO:0048770 pigment granule 7.93707874547838e-05 105 121 7 0.0578512396694215 0.0666666666666667
GO:CC GO:0045335 phagocytic vesicle 8.92735029797608e-05 137 95 7 0.0736842105263158 0.0510948905109489
GO:CC GO:0010008 endosome membrane 9.84466631372884e-05 505 143 15 0.104895104895105 0.0297029702970297
GO:CC GO:0012505 endomembrane system 0.000218660807904228 4640 143 58 0.405594405594406 0.0125
GO:CC GO:0005775 vacuolar lumen 0.000237343612940027 174 122 8 0.0655737704918033 0.0459770114942529
GO:CC GO:0035578 azurophil granule lumen 0.000362558078888153 91 122 6 0.0491803278688525 0.0659340659340659
GO:CC GO:1904813 ficolin-1-rich granule lumen 0.000518707917004623 124 141 7 0.049645390070922 0.0564516129032258
GO:CC GO:0062023 collagen-containing extracellular matrix 0.000532914630053598 421 133 12 0.0902255639097744 0.0285035629453682
GO:CC GO:0098588 bounding membrane of organelle 0.00064035583781391 2158 143 33 0.230769230769231 0.015291936978684
GO:CC GO:0101002 ficolin-1-rich granule 0.000831925525727598 184 141 8 0.0567375886524823 0.0434782608695652
GO:CC GO:0061702 inflammasome complex 0.00105298687598861 16 107 3 0.0280373831775701 0.1875
GO:CC GO:0031090 organelle membrane 0.00134965664207286 3612 143 46 0.321678321678322 0.0127353266888151
GO:CC GO:0030027 lamellipodium 0.0014407444417568 200 142 8 0.0563380281690141 0.04
GO:CC GO:0009986 cell surface 0.00201159163760973 899 121 16 0.132231404958678 0.017797552836485
GO:CC GO:0030670 phagocytic vesicle membrane 0.00245589636763865 76 139 5 0.0359712230215827 0.0657894736842105
GO:CC GO:0030139 endocytic vesicle 0.00276403219729569 306 104 8 0.0769230769230769 0.0261437908496732
GO:CC GO:0005938 cell cortex 0.00301142711754229 311 104 8 0.0769230769230769 0.0257234726688103
GO:CC GO:0005925 focal adhesion 0.0030646554140081 420 142 11 0.0774647887323944 0.0261904761904762
GO:CC GO:0055038 recycling endosome membrane 0.00334686601456451 84 139 5 0.0359712230215827 0.0595238095238095
GO:CC GO:0120025 plasma membrane bounded cell projection 0.00334686601456451 2229 7 5 0.714285714285714 0.00224315836698071
GO:CC GO:0030055 cell-substrate junction 0.00334686601456451 427 142 11 0.0774647887323944 0.0257611241217799
GO:CC GO:0005737 cytoplasm 0.0036195000205204 11911 143 109 0.762237762237762 0.0091512047687012
GO:CC GO:0043233 organelle lumen 0.00387919483037336 5565 11 9 0.818181818181818 0.00161725067385445
GO:CC GO:0042995 cell projection 0.00387919483037336 2330 7 5 0.714285714285714 0.00214592274678112
GO:CC GO:0031974 membrane-enclosed lumen 0.00387919483037336 5565 11 9 0.818181818181818 0.00161725067385445
GO:CC GO:0005774 vacuolar membrane 0.00416046619085021 441 143 11 0.0769230769230769 0.0249433106575964
GO:CC GO:0098562 cytoplasmic side of membrane 0.00419127091160472 194 37 4 0.108108108108108 0.0206185567010309
GO:CC GO:0016020 membrane 0.00431927471694751 9838 111 75 0.675675675675676 0.00762350071152673
GO:CC GO:0031012 extracellular matrix 0.00452955622117578 562 133 12 0.0902255639097744 0.0213523131672598
GO:CC GO:0030312 external encapsulating structure 0.00452955622117578 563 133 12 0.0902255639097744 0.0213143872113677
GO:CC GO:0098852 lytic vacuole membrane 0.00473204443325551 383 143 10 0.0699300699300699 0.0261096605744125
GO:CC GO:0005765 lysosomal membrane 0.00473204443325551 383 143 10 0.0699300699300699 0.0261096605744125
GO:CC GO:0005634 nucleus 0.00517326742664166 7592 11 10 0.909090909090909 0.00131717597471022
GO:CC GO:0012506 vesicle membrane 0.00544336020037368 800 139 15 0.107913669064748 0.01875
GO:CC GO:0031256 leading edge membrane 0.00563969336722245 175 119 6 0.0504201680672269 0.0342857142857143
GO:CC GO:0090543 Flemming body 0.00615738523708897 35 104 3 0.0288461538461538 0.0857142857142857
GO:CC GO:0005770 late endosome 0.00718994802600379 275 54 5 0.0925925925925926 0.0181818181818182
GO:CC GO:0031901 early endosome membrane 0.00734002147727558 159 139 6 0.0431654676258993 0.0377358490566038
GO:CC GO:0048471 perinuclear region of cytoplasm 0.00778101868774876 735 126 13 0.103174603174603 0.017687074829932
GO:CC GO:0030667 secretory granule membrane 0.0084891393323519 303 133 8 0.0601503759398496 0.0264026402640264
GO:CC GO:0031904 endosome lumen 0.0088300490963461 35 121 3 0.0247933884297521 0.0857142857142857
GO:CC GO:0032587 ruffle membrane 0.010016734333931 96 100 4 0.04 0.0416666666666667
GO:CC GO:0009898 cytoplasmic side of plasma membrane 0.0101124478575268 168 27 3 0.111111111111111 0.0178571428571429
GO:CC GO:0030659 cytoplasmic vesicle membrane 0.0102998364021536 779 139 14 0.100719424460432 0.0179717586649551
GO:CC GO:0098576 lumenal side of membrane 0.0103040299834706 33 139 3 0.0215827338129496 0.0909090909090909
GO:CC GO:0005769 early endosome 0.0108295158323323 378 139 9 0.0647482014388489 0.0238095238095238
GO:CC GO:0098552 side of membrane 0.011354742636516 619 139 12 0.0863309352517986 0.0193861066235864
GO:CC GO:0055037 recycling endosome 0.0136517517614316 188 139 6 0.0431654676258993 0.0319148936170213
GO:CC GO:0098858 actin-based cell projection 0.0136517517614316 220 119 6 0.0504201680672269 0.0272727272727273
GO:CC GO:0019897 extrinsic component of plasma membrane 0.0136517517614316 176 30 3 0.1 0.0170454545454545
GO:CC GO:0032154 cleavage furrow 0.0156713027513419 54 104 3 0.0288461538461538 0.0555555555555556
GO:CC GO:0043231 intracellular membrane-bounded organelle 0.0159904727054077 11296 11 11 1 0.000973796033994334
GO:CC GO:0043202 lysosomal lumen 0.0168332383037891 97 122 4 0.0327868852459016 0.0412371134020619
GO:CC GO:0030666 endocytic vesicle membrane 0.0195445931396799 159 78 4 0.0512820512820513 0.0251572327044025
GO:CC GO:0042383 sarcolemma 0.0195445931396799 140 89 4 0.0449438202247191 0.0285714285714286
GO:CC GO:0030134 COPII-coated ER to Golgi transport vesicle 0.0196148760416102 90 139 4 0.0287769784172662 0.0444444444444444
GO:CC GO:0030496 midbody 0.0201813679633821 196 104 5 0.0480769230769231 0.0255102040816327
GO:CC GO:0030175 filopodium 0.0202663547899334 107 119 4 0.0336134453781513 0.0373831775700935
GO:CC GO:0098791 Golgi apparatus subcompartment 0.0247075087134028 885 140 14 0.1 0.015819209039548
GO:CC GO:0031902 late endosome membrane 0.0249266945032206 140 50 3 0.06 0.0214285714285714
GO:CC GO:0070161 anchoring junction 0.0252271633157031 836 104 11 0.105769230769231 0.0131578947368421
GO:CC GO:0031226 intrinsic component of plasma membrane 0.0260101895670736 1726 105 18 0.171428571428571 0.0104287369640788
GO:CC GO:0033116 endoplasmic reticulum-Golgi intermediate compartment membrane 0.0267801665224464 74 99 3 0.0303030303030303 0.0405405405405405
GO:CC GO:0032153 cell division site 0.0277577656957259 72 104 3 0.0288461538461538 0.0416666666666667
GO:CC GO:0070469 respirasome 0.0297454997932553 103 76 3 0.0394736842105263 0.029126213592233
GO:CC GO:0098857 membrane microdomain 0.0305617231185921 335 131 7 0.0534351145038168 0.0208955223880597
GO:CC GO:0045121 membrane raft 0.0305617231185921 335 131 7 0.0534351145038168 0.0208955223880597
GO:CC GO:0043229 intracellular organelle 0.0331964534723729 12491 11 11 1 0.000880634056520695
GO:CC GO:0043227 membrane-bounded organelle 0.0334031440968966 12858 143 110 0.769230769230769 0.00855498522320734
GO:CC GO:0031984 organelle subcompartment 0.0334031440968966 1773 140 22 0.157142857142857 0.0124083474337281
GO:CC GO:0005793 endoplasmic reticulum-Golgi intermediate compartment 0.0334031440968966 131 123 4 0.032520325203252 0.0305343511450382
GO:CC GO:0031253 cell projection membrane 0.0349602432922499 343 104 6 0.0576923076923077 0.0174927113702624
GO:CC GO:0000139 Golgi membrane 0.0354104970911246 771 140 12 0.0857142857142857 0.0155642023346304
GO:CC GO:0030426 growth cone 0.0364645299789201 187 141 5 0.0354609929078014 0.0267379679144385
GO:CC GO:0019898 extrinsic component of membrane 0.0364645299789201 313 30 3 0.1 0.00958466453674121
GO:CC GO:0005829 cytosol 0.0366971584658688 5303 138 51 0.369565217391304 0.00961719781255893
GO:CC GO:0042581 specific granule 0.036845705789294 158 113 4 0.0353982300884956 0.0253164556962025
GO:CC GO:0030427 site of polarized growth 0.036845705789294 193 141 5 0.0354609929078014 0.0259067357512953
GO:CC GO:0005887 integral component of plasma membrane 0.0438580272508133 1645 105 16 0.152380952380952 0.00972644376899696
GO:CC GO:0032432 actin filament bundle 0.0453349534147578 76 142 3 0.0211267605633803 0.0394736842105263
GO:CC GO:0043228 non-membrane-bounded organelle 0.0494337778279497 5346 3 3 1 0.000561167227833895
GO:CC GO:0043232 intracellular non-membrane-bounded organelle 0.0494337778279497 5338 3 3 1 0.000562008242787561
GO:MF GO:0044548 S100 protein binding 0.000669951623095737 14 30 3 0.1 0.214285714285714
GO:MF GO:0048306 calcium-dependent protein binding 0.000702028823347706 82 7 3 0.428571428571429 0.0365853658536585
GO:MF GO:0004197 cysteine-type endopeptidase activity 0.00229103882998562 121 121 7 0.0578512396694215 0.0578512396694215
GO:MF GO:0097153 cysteine-type endopeptidase activity involved in apoptotic process 0.00457968197769721 15 85 3 0.0352941176470588 0.2
GO:MF GO:0045296 cadherin binding 0.00457968197769721 333 94 9 0.0957446808510638 0.027027027027027
GO:MF GO:0005509 calcium ion binding 0.00534572766804772 721 7 4 0.571428571428571 0.00554785020804438
GO:MF GO:0016505 peptidase activator activity involved in apoptotic process 0.00534572766804772 19 82 3 0.0365853658536585 0.157894736842105
GO:MF GO:0008092 cytoskeletal protein binding 0.00688593888763574 996 6 4 0.666666666666667 0.00401606425702811
GO:MF GO:0050839 cell adhesion molecule binding 0.00805775469905236 546 101 11 0.108910891089109 0.0201465201465201
GO:MF GO:0008234 cysteine-type peptidase activity 0.00805775469905236 180 121 7 0.0578512396694215 0.0388888888888889
GO:MF GO:0051015 actin filament binding 0.00879408949265053 212 142 8 0.0563380281690141 0.0377358490566038
GO:MF GO:0016504 peptidase activator activity 0.00879408949265053 42 134 4 0.0298507462686567 0.0952380952380952
GO:MF GO:0003779 actin binding 0.00924272616559677 448 6 3 0.5 0.00669642857142857
GO:MF GO:0042802 identical protein binding 0.00950685251056158 2067 7 5 0.714285714285714 0.00241896468311563
GO:MF GO:0019956 chemokine binding 0.0120335346852814 33 89 3 0.0337078651685393 0.0909090909090909
GO:MF GO:0008047 enzyme activator activity 0.0120335346852814 540 134 12 0.0895522388059701 0.0222222222222222
GO:MF GO:0016787 hydrolase activity 0.0120335346852814 2615 132 33 0.25 0.0126195028680688
GO:MF GO:0098772 molecular function regulator 0.0120570577236937 2363 134 31 0.23134328358209 0.0131189166314008
GO:MF GO:0004175 endopeptidase activity 0.0133631967350161 450 121 10 0.0826446280991736 0.0222222222222222
GO:MF GO:0044877 protein-containing complex binding 0.0146685574621552 1287 124 19 0.153225806451613 0.0147630147630148
GO:MF GO:0042803 protein homodimerization activity 0.0157555176418149 676 100 11 0.11 0.0162721893491124
GO:MF GO:0061134 peptidase regulator activity 0.0167610072514705 224 134 7 0.0522388059701493 0.03125
GO:MF GO:0042605 peptide antigen binding 0.0190297410954736 30 139 3 0.0215827338129496 0.1
GO:MF GO:0019955 cytokine binding 0.0190465991494058 138 113 5 0.0442477876106195 0.036231884057971
GO:MF GO:0019904 protein domain specific binding 0.0190465991494058 710 34 6 0.176470588235294 0.00845070422535211
GO:MF GO:0030234 enzyme regulator activity 0.0190465991494058 1248 134 19 0.141791044776119 0.015224358974359
GO:MF GO:0008233 peptidase activity 0.0191294104500514 646 129 12 0.0930232558139535 0.0185758513931889
GO:MF GO:0050840 extracellular matrix binding 0.0235947974071451 56 89 3 0.0337078651685393 0.0535714285714286
GO:MF GO:0002020 protease binding 0.0237558523533153 133 133 5 0.037593984962406 0.037593984962406
GO:MF GO:0098631 cell adhesion mediator activity 0.0237558523533153 58 89 3 0.0337078651685393 0.0517241379310345
GO:MF GO:0004180 carboxypeptidase activity 0.0254141061337444 43 129 3 0.0232558139534884 0.0697674418604651
GO:MF GO:0008238 exopeptidase activity 0.0272023887496611 95 129 4 0.0310077519379845 0.0421052631578947
GO:MF GO:0046983 protein dimerization activity 0.0284273136342119 1069 100 13 0.13 0.0121608980355472
GO:MF GO:0019899 enzyme binding 0.0292353823088429 2074 138 26 0.188405797101449 0.0125361620057859
GO:MF GO:0005102 signaling receptor binding 0.0292353823088429 1672 112 19 0.169642857142857 0.0113636363636364
GO:MF GO:0019887 protein kinase regulator activity 0.0333698343981757 191 112 5 0.0446428571428571 0.0261780104712042
GO:MF GO:0140375 immune receptor activity 0.0340722495894911 133 102 4 0.0392156862745098 0.0300751879699248
GO:MF GO:0004860 protein kinase inhibitor activity 0.0341200367558156 70 100 3 0.03 0.0428571428571429
GO:MF GO:0019210 kinase inhibitor activity 0.03727333956703 74 100 3 0.03 0.0405405405405405
GO:MF GO:0003823 antigen binding 0.0373497122318522 163 139 5 0.0359712230215827 0.0306748466257669
GO:MF GO:0044389 ubiquitin-like protein ligase binding 0.0401016034446869 314 138 7 0.0507246376811594 0.0222929936305732
GO:MF GO:0003723 RNA binding 0.042155963561076 1943 5 3 0.6 0.00154400411734431
GO:MF GO:0008236 serine-type peptidase activity 0.0433610577496756 189 129 5 0.0387596899224806 0.0264550264550265
GO:MF GO:0019207 kinase regulator activity 0.044126233030066 221 112 5 0.0446428571428571 0.0226244343891403
GO:MF GO:0017171 serine hydrolase activity 0.044126233030066 193 129 5 0.0387596899224806 0.0259067357512953
GO:MF GO:0005518 collagen binding 0.044126233030066 70 121 3 0.0247933884297521 0.0428571428571429
GO:MF GO:0004857 enzyme inhibitor activity 0.044126233030066 385 42 4 0.0952380952380952 0.0103896103896104
GO:MF GO:0005516 calmodulin binding 0.0451724989178865 204 124 5 0.0403225806451613 0.0245098039215686
HPA HPA:0530713 spleen; cells in red pulp[High] 0.0197214602452965 778 8 5 0.625 0.006426735218509
HPA HPA:0530712 spleen; cells in red pulp[≥Medium] 0.0197214602452965 3049 10 9 0.9 0.00295178747130207
HPA HPA:0530711 spleen; cells in red pulp[≥Low] 0.0268064999645178 5195 11 11 1 0.00211742059672762
HPA HPA:0030073 appendix; lymphoid tissue[High] 0.0268064999645178 803 3 3 1 0.0037359900373599
HPA HPA:0060841 bronchus; basal cells[≥Low] 0.0268064999645178 352 31 6 0.193548387096774 0.0170454545454545
HPA HPA:0091021 cerebellum; processes in granular layer[≥Low] 0.0268064999645178 206 7 3 0.428571428571429 0.0145631067961165
HPA HPA:0300413 lung; macrophages[High] 0.0268064999645178 1224 7 5 0.714285714285714 0.00408496732026144
HPA HPA:0030071 appendix; lymphoid tissue[≥Low] 0.0317719069504585 4976 9 9 1 0.00180868167202572
HPA HPA:0310431 lymph node; germinal center cells[≥Low] 0.0317719069504585 4935 9 9 1 0.00182370820668693
HPA HPA:0310443 lymph node; non-germinal center cells[High] 0.0317719069504585 1169 5 4 0.8 0.00342172797262618
HPA HPA:0310442 lymph node; non-germinal center cells[≥Medium] 0.0317719069504585 3875 135 67 0.496296296296296 0.0172903225806452
HPA HPA:0530000 spleen 0.0317719069504585 5756 11 11 1 0.00191104933981932
HPA HPA:0600443 tonsil; non-germinal center cells[High] 0.0317719069504585 1271 5 4 0.8 0.003147128245476
HPA HPA:0040083 bone marrow; hematopoietic cells[High] 0.0345921165468312 1376 5 4 0.8 0.00290697674418605
KEGG KEGG:04142 Lysosome 0.00252043653713149 128 143 11 0.0769230769230769 0.0859375
KEGG KEGG:04621 NOD-like receptor signaling pathway 0.0396915849560154 177 128 10 0.078125 0.0564971751412429
MIRNA MIRNA:hsa-miR-1-3p hsa-miR-1-3p 0.0102500224353639 915 30 10 0.333333333333333 0.0109289617486339
REAC REAC:R-HSA-168256 Immune System 5.45063465541243e-06 2139 141 58 0.411347517730496 0.0271154745208041
REAC REAC:R-HSA-168249 Innate Immune System 3.26418361019516e-05 1073 141 36 0.25531914893617 0.0335507921714818
REAC REAC:R-HSA-913531 Interferon Signaling 3.44356394647363e-05 191 139 14 0.100719424460432 0.0732984293193717
REAC REAC:R-HSA-6798695 Neutrophil degranulation 3.70106697562236e-05 474 141 22 0.156028368794326 0.0464135021097046
REAC REAC:R-HSA-909733 Interferon alpha/beta signaling 0.000225885512331685 66 139 8 0.0575539568345324 0.121212121212121
REAC REAC:R-HSA-1280215 Cytokine Signaling in Immune system 0.00785472136908278 842 139 25 0.179856115107914 0.0296912114014252
REAC REAC:R-HSA-877300 Interferon gamma signaling 0.0103612372513134 87 139 7 0.0503597122302158 0.0804597701149425
TF TF:M11671 Factor: IRF-5; motif: NCGAAACCGAAACY 0.0033129990563798 389 128 13 0.1015625 0.0334190231362468
TF TF:M10073 Factor: PU.1; motif: NRAAAGAGGAAGTGRNN 0.0033129990563798 2416 52 20 0.384615384615385 0.00827814569536424
TF TF:M11685_1 Factor: IRF-8; motif: NCGAAACYGAAACYN; match class: 1 0.0033129990563798 118 128 8 0.0625 0.0677966101694915
TF TF:M10074 Factor: Spi-B; motif: NRAAAGAGGAAGTGARA 0.00361413235999768 1611 52 16 0.307692307692308 0.00993171942892613
TF TF:M10435 Factor: Sp2; motif: GGGGCGGGG 0.00494784762438052 7696 142 82 0.577464788732394 0.0106548856548857
TF TF:M07063 Factor: Sp1; motif: GGGGCGGGGC 0.00494784762438052 7696 142 82 0.577464788732394 0.0106548856548857
TF TF:M10071_1 Factor: Sp1; motif: NGGGGGCGGGGCCNGGGGGGGG; match class: 1 0.00546860483501974 4623 142 57 0.401408450704225 0.0123296560674886
TF TF:M09765_1 Factor: SP1; motif: NRGKGGGCGGGGCN; match class: 1 0.00546860483501974 3318 142 45 0.316901408450704 0.0135623869801085
TF TF:M09970_1 Factor: KLF3; motif: NNNNNNGGGCGGGGCNNGN; match class: 1 0.00546860483501974 3783 142 49 0.345070422535211 0.0129526830557758
TF TF:M00453_1 Factor: IRF-7; motif: TNSGAAWNCGAAANTNNN; match class: 1 0.00546860483501974 332 129 11 0.0852713178294574 0.0331325301204819
TF TF:M04018 Factor: IRF7; motif: NCGAAARYGAAANT 0.00546860483501974 619 128 15 0.1171875 0.024232633279483
TF TF:M11679 Factor: IRF-7; motif: NCGAAANCGAAANYN 0.00546860483501974 622 128 15 0.1171875 0.0241157556270096
TF TF:M04020_1 Factor: IRF8; motif: NCGAAACCGAAACT; match class: 1 0.00546860483501974 45 128 5 0.0390625 0.111111111111111
TF TF:M11685 Factor: IRF-8; motif: NCGAAACYGAAACYN 0.00546860483501974 1617 143 28 0.195804195804196 0.0173160173160173
TF TF:M04015_1 Factor: IRF-4; motif: NCGAAACCGAAACYA; match class: 1 0.00546860483501974 158 128 8 0.0625 0.0506329113924051
TF TF:M02078 Factor: SPI1; motif: NGRGGAAGTN 0.00568857193523842 3506 105 37 0.352380952380952 0.0105533371363377
TF TF:M11673 Factor: IRF-5; motif: NCGAAACCGAAACY 0.00572529872960846 57 108 5 0.0462962962962963 0.087719298245614
TF TF:M11664 Factor: IRF-2; motif: NGAAASYGAAAS 0.00659088571101213 1651 143 28 0.195804195804196 0.0169594185342217
TF TF:M07103 Factor: JunB; motif: NRRTGASTCAK 0.0131693989781259 2383 36 14 0.388888888888889 0.0058749475451112
TF TF:M03866 Factor: c-Fos:c-Jun; motif: NTGACTCAN 0.0134178446129782 1626 57 15 0.263157894736842 0.00922509225092251
TF TF:M09957_1 Factor: IRF-2; motif: NAAANNGAAAGTGAAASTRN; match class: 1 0.014863685566953 22 64 3 0.046875 0.136363636363636
TF TF:M08934 Factor: JUND; motif: NATGAGTCAT 0.0161320150711642 4329 39 20 0.512820512820513 0.00462000462000462
TF TF:M11297_1 Factor: jdp2; motif: NRTGASTCAYN; match class: 1 0.0164299728736365 1667 34 11 0.323529411764706 0.00659868026394721
TF TF:M09924 Factor: c-Fos; motif: NTGAGTCAN 0.0164299728736365 2431 37 14 0.378378378378378 0.00575894693541752
TF TF:M00339_1 Factor: c-Ets-1; motif: RCAGGAAGTGNNTNS; match class: 1 0.0164299728736365 1466 103 20 0.194174757281553 0.0136425648021828
TF TF:M10072_1 Factor: sp4; motif: NNGNARGRGGCGGRGCNNRR; match class: 1 0.0164299728736365 6225 142 67 0.471830985915493 0.0107630522088353
TF TF:M11664_1 Factor: IRF-2; motif: NGAAASYGAAAS; match class: 1 0.0164299728736365 140 98 6 0.0612244897959184 0.0428571428571429
TF TF:M09631 Factor: JunB; motif: NNNTGAGTCAY 0.0164299728736365 1915 51 15 0.294117647058824 0.00783289817232376
TF TF:M04482 Factor: RARA; motif: ARRGGTCANSNGAGGTCA 0.0173908592528322 3852 111 39 0.351351351351351 0.0101246105919003
TF TF:M09658 Factor: Sp2; motif: GGSNNGGGGGCGGGGCCNGNGS 0.0173908592528322 5262 142 59 0.415492957746479 0.0112124667426834
TF TF:M08881 Factor: ETSLIKE; motif: NACTTCCTNN 0.0198352260629447 3140 142 40 0.28169014084507 0.0127388535031847
TF TF:M00971 Factor: Ets; motif: ACTTCCTS 0.0198352260629447 2349 132 31 0.234848484848485 0.0131971051511281
TF TF:M08942 Factor: C-FOS:C-JUN; motif: ATGAGTCAYN 0.0198352260629447 3289 37 16 0.432432432432432 0.00486470051687443
TF TF:M08936 Factor: C-JUN:FOSB; motif: NATGACTCAY 0.0198352260629447 3271 37 16 0.432432432432432 0.00489147049831856
TF TF:M01224 Factor: P50:RELA-P65; motif: GGANTTYCCCWN 0.0198352260629447 2329 23 10 0.434782608695652 0.004293688278231
TF TF:M11297 Factor: jdp2; motif: NRTGASTCAYN 0.0198352260629447 1811 34 11 0.323529411764706 0.00607399226946438
TF TF:M07395 Factor: Sp1; motif: NGGGGCGGGGN 0.0198352260629447 10640 143 99 0.692307692307692 0.00930451127819549
TF TF:M09659 Factor: PU.1; motif: NRAAAGAGGAAGTGARA 0.0198352260629447 2523 61 19 0.311475409836066 0.00753071739992073
TF TF:M03807 Factor: SP2; motif: GNNGGGGGCGGGGSN 0.0198352260629447 8415 143 83 0.58041958041958 0.00986333927510398
TF TF:M07615 Factor: Sp3; motif: GGGGCGGGGSNN 0.0198352260629447 6807 142 71 0.5 0.0104304392537094
TF TF:M00721 Factor: CACCC-binding; motif: CANCCNNWGGGTGDGG 0.0198352260629447 2925 33 14 0.424242424242424 0.00478632478632479
TF TF:M10144_1 Factor: ZNF341; motif: GRGGRRNRGNRGNRGGAASAGC; match class: 1 0.0198352260629447 972 3 3 1 0.00308641975308642
TF TF:M11665 Factor: IRF-2; motif: NGAAASYGAAAS 0.0198352260629447 2396 129 31 0.24031007751938 0.0129382303839733
TF TF:M10530_1 Factor: sp4; motif: NNNGCYCCGCCCCCY; match class: 1 0.0198352260629447 3780 135 44 0.325925925925926 0.0116402116402116
TF TF:M08671 Factor: AP-4:Dlx-3; motif: NCAGCTGNNNNNNGTAATKR 0.0198352260629447 4413 6 6 1 0.00135961930659415
TF TF:M09970 Factor: KLF3; motif: NNNNNNGGGCGGGGCNNGN 0.0198352260629447 7728 143 78 0.545454545454545 0.0100931677018634
TF TF:M07277_1 Factor: BTEB2; motif: RGGGNGKGGN; match class: 1 0.0198352260629447 4149 142 49 0.345070422535211 0.0118100747167992
TF TF:M02242_1 Factor: CTCF; motif: YNRCCASYAGRKGGCRSYN; match class: 1 0.0214668452460294 1253 56 12 0.214285714285714 0.00957701516360734
TF TF:M11265 Factor: c-Jun; motif: NATGACTCATN 0.0214668452460294 4632 6 6 1 0.00129533678756477
TF TF:M00931 Factor: Sp1; motif: GGGGCGGGGC 0.0216342338511686 10281 143 96 0.671328671328671 0.0093376130726583
TF TF:M03807_1 Factor: SP2; motif: GNNGGGGGCGGGGSN; match class: 1 0.0216342338511686 4199 142 49 0.345070422535211 0.0116694451059776
TF TF:M11374 Factor: Spi-B; motif: NAWGRGGAAGTR 0.0216342338511686 2512 131 32 0.244274809160305 0.0127388535031847
TF TF:M11686 Factor: IRF-4; motif: NYGAAASYGAAACYN 0.0216342338511686 3391 129 39 0.302325581395349 0.0115010321439104
TF TF:M09617 Factor: c-Fos; motif: RTGAGTCAYNN 0.0216342338511686 2663 37 14 0.378378378378378 0.00525722868944799
TF TF:M09808 Factor: KLF4; motif: MCACACCCTNN 0.0218833725667164 3799 37 17 0.459459459459459 0.00447486180573835
TF TF:M07460 Factor: KLF3; motif: CCMCRCCCNG 0.0218833725667164 1437 30 9 0.3 0.00626304801670146
TF TF:M00196_1 Factor: Sp1; motif: NGGGGGCGGGGYN; match class: 1 0.0218833725667164 5919 142 63 0.443661971830986 0.0106436898124683
TF TF:M11681 Factor: IRF-9; motif: NCGAAACYGAAACYN 0.0218833725667164 97 108 5 0.0462962962962963 0.0515463917525773
TF TF:M10071 Factor: Sp1; motif: NGGGGGCGGGGCCNGGGGGGGG 0.0227830449815659 8495 143 83 0.58041958041958 0.00977045320776928
TF TF:M00771_1 Factor: Ets; motif: ANNCACTTCCTG; match class: 1 0.0237549117259983 445 92 9 0.0978260869565217 0.0202247191011236
TF TF:M04020 Factor: IRF8; motif: NCGAAACCGAAACT 0.0237549117259983 992 128 17 0.1328125 0.0171370967741935
TF TF:M11387 Factor: elf5; motif: NNNNMGGAAGTN 0.0237549117259983 2598 52 17 0.326923076923077 0.00654349499615089
TF TF:M04015 Factor: IRF-4; motif: NCGAAACCGAAACYA 0.023872037291992 2038 128 27 0.2109375 0.0132482826300294
TF TF:M08962 Factor: PPARGAMMA:RXR-ALPHA; motif: NNRGGTCAAWAGGTCAN 0.0239262323368303 4787 137 52 0.37956204379562 0.0108627532901609
TF TF:M11677 Factor: IRF-3; motif: NGGAAACNGAAACCGAAACN 0.0241720164061273 470 128 11 0.0859375 0.0234042553191489
TF TF:M09765 Factor: SP1; motif: NRGKGGGCGGGGCN 0.0248248895121186 7469 143 75 0.524475524475524 0.0100415048868657
TF TF:M01857_1 Factor: AP-2alpha; motif: NGCCYSNNGSN; match class: 1 0.0248248895121186 4616 142 52 0.366197183098592 0.011265164644714
TF TF:M11388 Factor: elf5; motif: AANRAGGAAGTR 0.0249829223643539 660 51 8 0.156862745098039 0.0121212121212121
TF TF:M00665_1 Factor: Sp3; motif: ASMCTTGGGSRGGG; match class: 1 0.0253284308213787 2293 25 10 0.4 0.00436109899694723
TF TF:M09902 Factor: ESE-1; motif: NNANVAGGAAGTNN 0.025714270920089 3200 139 39 0.280575539568345 0.0121875
TF TF:M00196 Factor: Sp1; motif: NGGGGGCGGGGYN 0.025714270920089 10233 143 95 0.664335664335664 0.0092836900224763
TF TF:M07091 Factor: Fra-1; motif: RRTGASTCAKN 0.025714270920089 1716 57 14 0.245614035087719 0.00815850815850816
TF TF:M08920 Factor: JUNB:FOSB; motif: NRTGASTCAT 0.0258851986045651 3151 37 15 0.405405405405405 0.0047603935258648
TF TF:M12191 Factor: GATA-2; motif: NNGATAASN 0.0258851986045651 1483 81 16 0.197530864197531 0.0107889413351315
TF TF:M07092 Factor: Fra-2; motif: NRRTGASTCAB 0.026008064882095 3156 37 15 0.405405405405405 0.00475285171102662
TF TF:M08887 Factor: IRF; motif: NNGAAANTGAAANN 0.0264165461391262 1267 143 21 0.146853146853147 0.0165745856353591
TF TF:M02111_1 Factor: NR1B2; motif: NTGACCY; match class: 1 0.0264165461391262 3323 117 35 0.299145299145299 0.0105326512187782
TF TF:M04932 Factor: Sp2; motif: AAGGGGCGG 0.0267154019034292 2593 78 22 0.282051282051282 0.0084843810258388
TF TF:M07379 Factor: c-Ets-2; motif: NNCTTCCTNNN 0.0268670696863281 3487 142 42 0.295774647887324 0.0120447375967881
TF TF:M04014 Factor: IRF3; motif: NNRRAANGGAAACCGAAACYR 0.0272706251260314 278 67 6 0.0895522388059701 0.0215827338129496
TF TF:M11684_1 Factor: IRF-8; motif: NYGAAACYGAAACTN; match class: 1 0.0272706251260314 832 129 15 0.116279069767442 0.0180288461538462
TF TF:M00932 Factor: Sp1; motif: NNGGGGCGGGGNN 0.0272706251260314 10419 143 96 0.671328671328671 0.00921393607831846
TF TF:M01220 Factor: STAT3:STAT3; motif: TTKMCGGGAAMTSC 0.0272706251260314 1026 35 8 0.228571428571429 0.00779727095516569
TF TF:M00931_1 Factor: Sp1; motif: GGGGCGGGGC; match class: 1 0.0272706251260314 5905 142 62 0.436619718309859 0.0104995766299746
TF TF:M08940 Factor: C-JUN:FRA-2; motif: NNRTGAGTCAYN 0.0305989363119176 3631 51 20 0.392156862745098 0.00550812448361333
TF TF:M10056_1 Factor: DRRS; motif: GNNGGGWGGG; match class: 1 0.0310491170646959 980 21 6 0.285714285714286 0.00612244897959184
TF TF:M11683 Factor: IRF-8; motif: NCGAAACCGAAACYN 0.0310491170646959 4690 129 48 0.372093023255814 0.0102345415778252
TF TF:M12351_1 Factor: TIEG1; motif: NCCCNSNCCCCGCCCCC; match class: 1 0.0315062158562002 8180 142 79 0.556338028169014 0.00965770171149144
TF TF:M03567 Factor: Sp2; motif: NYSGCCCCGCCCCCY 0.0315062158562002 7710 143 76 0.531468531468531 0.00985732814526589
TF TF:M07129_1 Factor: Sp2; motif: GYCCCGCCYCYNNNN; match class: 1 0.0315062158562002 2422 142 32 0.225352112676056 0.0132122213047069
TF TF:M11682 Factor: IRF-8; motif: NYGAAASYGAAACYN 0.0319305479175761 3795 129 41 0.317829457364341 0.0108036890645586
TF TF:M09725 Factor: DREF; motif: CTYYCWCTTCCY 0.0320561627573245 7519 62 37 0.596774193548387 0.00492086713658731
TF TF:M00933 Factor: Sp1; motif: CCCCGCCCCN 0.0320561627573245 9715 142 90 0.633802816901408 0.00926402470406588
TF TF:M09645 Factor: Pax-5; motif: NNNNRNKCAGCNRAGCGTGAC 0.0322673058654321 2596 85 23 0.270588235294118 0.0088597842835131
TF TF:M00925 Factor: AP-1; motif: NTGACTCAN 0.0322673058654321 2554 37 13 0.351351351351351 0.00509005481597494
TF TF:M07600 Factor: C-Fos; motif: NNTGACTCAN 0.0333875318677067 2834 51 17 0.333333333333333 0.00599858856739591
TF TF:M09903 Factor: elf5; motif: NNNANSAGGAAGTNN 0.0334283425875012 1243 24 7 0.291666666666667 0.00563153660498793
TF TF:M11672 Factor: IRF-5; motif: NCGAAACCGAAACY 0.0334283425875012 120 108 5 0.0462962962962963 0.0416666666666667
TF TF:M08271 Factor: Erm:TBR2; motif: NNGTGNKANNNNNNNNTNNCRSCGGAWGN 0.033476326318003 500 7 3 0.428571428571429 0.006
TF TF:M00083_1 Factor: MZF-1; motif: NGNGGGGA; match class: 1 0.0350048246122465 295 26 4 0.153846153846154 0.0135593220338983
TF TF:M00453 Factor: IRF-7; motif: TNSGAAWNCGAAANTNNN 0.0350048246122465 3082 129 35 0.271317829457364 0.0113562621674238
TF TF:M08295_1 Factor: FOXO1A:Elf-1; motif: NAGAAAACCGAANM; match class: 1 0.0350048246122465 4997 123 48 0.390243902439024 0.00960576345807485
TF TF:M11670 Factor: IRF-5; motif: NYGAAACCGAAACY 0.035310053786512 871 129 15 0.116279069767442 0.0172215843857635
TF TF:M07092_1 Factor: Fra-2; motif: NRRTGASTCAB; match class: 1 0.0356217961812168 1144 34 8 0.235294117647059 0.00699300699300699
TF TF:M11682_1 Factor: IRF-8; motif: NYGAAASYGAAACYN; match class: 1 0.0357471550784298 543 123 11 0.0894308943089431 0.0202578268876611
TF TF:M12313_1 Factor: ZNF460; motif: NNACNCCCCCCNN; match class: 1 0.0357471550784298 2203 132 28 0.212121212121212 0.0127099409895597
TF TF:M12188_1 Factor: KLF17; motif: NGMCMCRCCCTN; match class: 1 0.0358083110264336 588 64 8 0.125 0.0136054421768707
TF TF:M11375 Factor: Spi-B; motif: NAWGCGGAAGTN 0.0358359338460664 2608 51 16 0.313725490196078 0.00613496932515337
TF TF:M04810_1 Factor: USF2; motif: AAGTCACG; match class: 1 0.0368996381658571 987 9 4 0.444444444444444 0.00405268490374873
TF TF:M09591_1 Factor: AP-2gamma; motif: NTGSCCTGRGGSNN; match class: 1 0.0371627081141616 2821 66 20 0.303030303030303 0.00708968450903935
TF TF:M01588_1 Factor: GKLF; motif: GCCMCRCCCNNN; match class: 1 0.0386840824622869 3962 142 45 0.316901408450704 0.0113579000504796
TF TF:M12207 Factor: GATA-4; motif: NNGATAASNN 0.0386840824622869 2844 39 14 0.358974358974359 0.00492264416315049
TF TF:M00932_1 Factor: Sp1; motif: NNGGGGCGGGGNN; match class: 1 0.0386840824622869 6047 142 62 0.436619718309859 0.0102530180254672
TF TF:M08887_1 Factor: IRF; motif: NNGAAANTGAAANN; match class: 1 0.0386840824622869 73 108 4 0.037037037037037 0.0547945205479452
TF TF:M11680 Factor: IRF-9; motif: NYGAAACYGAAACYN 0.0386840824622869 128 108 5 0.0462962962962963 0.0390625
TF TF:M11237 Factor: OASIS; motif: NTGCCACGYGTRCR 0.0387543176378249 70 115 4 0.0347826086956522 0.0571428571428571
TF TF:M00258_1 Factor: ISGF-3; motif: CAGTTTCWCTTTYCC; match class: 1 0.0387543176378249 30 117 3 0.0256410256410256 0.1
TF TF:M00983 Factor: MAF; motif: NGCTGAGTCAN 0.0387543176378249 6031 19 13 0.684210526315789 0.00215552976289173
TF TF:M12173 Factor: GKLF; motif: NNCCMCRCCCN 0.0387543176378249 10023 143 92 0.643356643356643 0.00917888855632046
TF TF:M08922 Factor: JUNB:FRA-1; motif: NNRTGACTCATNN 0.0387543176378249 1834 34 10 0.294117647058824 0.0054525627044711
TF TF:M07461_1 Factor: KLF; motif: GGGNGGGG; match class: 1 0.0387543176378249 3397 30 13 0.433333333333333 0.00382690609361201
TF TF:M01303 Factor: SP1; motif: GGGGYGGGGNS 0.0387543176378249 7898 142 76 0.535211267605634 0.00962268928842745
TF TF:M01203 Factor: SPI1; motif: NNAAWGNGGAASTNNNN 0.0387543176378249 2643 51 16 0.313725490196078 0.006053726825577
TF TF:M09723 Factor: BTEB1; motif: GGGGGCGGGGCNGSGGGNGS 0.0388868252263606 10156 74 52 0.702702702702703 0.0051201260338716
TF TF:M12313 Factor: ZNF460; motif: NNACNCCCCCCNN 0.0391978783726878 5825 128 55 0.4296875 0.00944206008583691
TF TF:M08944 Factor: JUNB:C-JUN; motif: NATGACKCAT 0.0391978783726878 5313 41 21 0.51219512195122 0.00395256916996047
TF TF:M07395_1 Factor: Sp1; motif: NGGGGCGGGGN; match class: 1 0.0391978783726878 6334 142 64 0.450704225352113 0.0101041995579413
TF TF:M00051_1 Factor: NF-kappaB; motif: GGGGATYCCC; match class: 1 0.0391978783726878 2797 92 25 0.271739130434783 0.00893814801573114
TF TF:M11676 Factor: IRF-3; motif: NGGAAANGGAAASNGAAACN 0.0391978783726878 562 143 12 0.0839160839160839 0.0213523131672598
TF TF:M00517_1 Factor: AP-1; motif: NNNTGAGTCAKCN; match class: 1 0.0391978783726878 3227 51 18 0.352941176470588 0.00557793616361946
TF TF:M11686_1 Factor: IRF-4; motif: NYGAAASYGAAACYN; match class: 1 0.04011782734886 452 108 9 0.0833333333333333 0.0199115044247788
TF TF:M07260_1 Factor: Ikaros; motif: TGGGAGN; match class: 1 0.04011782734886 7187 7 7 1 0.000973980798664255
TF TF:M04711 Factor: PU.1; motif: ACTTCCTCT 0.0402301473097685 1712 131 23 0.175572519083969 0.0134345794392523
TF TF:M00431 Factor: E2F-1; motif: TTTSGCGS 0.0403811426943223 7257 72 40 0.555555555555556 0.00551191952597492
TF TF:M11446 Factor: Elf-1; motif: RANSMGGAAGTR 0.0403811426943223 2915 52 17 0.326923076923077 0.00583190394511149
TF TF:M04738 Factor: ER-alpha; motif: AGGTCANMNTGACC 0.0403811426943223 4374 142 48 0.338028169014085 0.0109739368998628
TF TF:M01859 Factor: AP-2; motif: NNGCCTK 0.0403811426943223 7799 38 25 0.657894736842105 0.00320553917168868
TF TF:M08925 Factor: JUNB:C-FOS; motif: NATGAGTCATNN 0.0403811426943223 3490 37 15 0.405405405405405 0.00429799426934097
TF TF:M03552 Factor: JunD; motif: TGACTCAN 0.0403811426943223 936 34 7 0.205882352941176 0.00747863247863248
TF TF:M03538 Factor: AP-1; motif: TGACTCAN 0.0403811426943223 936 34 7 0.205882352941176 0.00747863247863248
TF TF:M11488 Factor: CP2; motif: WACCGGTTNNAACCGGWT 0.0403811426943223 3424 34 14 0.411764705882353 0.00408878504672897
TF TF:M03579 Factor: PEA3; motif: AGGAAGT 0.0403811426943223 6837 133 64 0.481203007518797 0.00936083077373117
TF TF:M01870 Factor: C-ets-1; motif: AGGAAGN 0.0403811426943223 6837 133 64 0.481203007518797 0.00936083077373117
TF TF:M07382 Factor: Fli-1; motif: MGGAAGT 0.0403811426943223 6837 133 64 0.481203007518797 0.00936083077373117
TF TF:M09723_1 Factor: BTEB1; motif: GGGGGCGGGGCNGSGGGNGS; match class: 1 0.0403811426943223 6113 142 62 0.436619718309859 0.0101423196466547
TF TF:M07277 Factor: BTEB2; motif: RGGGNGKGGN 0.0403811426943223 8492 142 80 0.563380281690141 0.00942063118228921
TF TF:M02278 Factor: SPI1; motif: AGGAAGT 0.0403811426943223 6837 133 64 0.481203007518797 0.00936083077373117
TF TF:M04896 Factor: AP-2alpha; motif: NNNGSCCTGRGGSN 0.0403811426943223 5780 121 52 0.429752066115702 0.00899653979238754
TF TF:M00172_1 Factor: AP-1; motif: RSTGACTNMNW; match class: 1 0.0408978475168016 152 57 4 0.0701754385964912 0.0263157894736842
TF TF:M08929 Factor: JUND:FRA-1; motif: NRTGACTCAN 0.0418654850875085 1560 34 9 0.264705882352941 0.00576923076923077
TF TF:M03815 Factor: c-Fos; motif: TGACTCAN 0.0418654850875085 2455 51 15 0.294117647058824 0.00610997963340122
TF TF:M11687_1 Factor: IRF-4; motif: NCGAAACCGAAACYN; match class: 1 0.0433499065146705 474 128 10 0.078125 0.0210970464135021
TF TF:M11792 Factor: NR1B1; motif: NRGGTCANRRGGTCAN 0.0433499065146705 4845 18 11 0.611111111111111 0.0022703818369453
TF TF:M00658_1 Factor: PU.1; motif: WGAGGAAG; match class: 1 0.0434568494923857 638 7 3 0.428571428571429 0.00470219435736677
TF TF:M03810 Factor: RXR:PXR; motif: NNNTGAMCTYNNNTGAMCYN 0.0444397482497194 1360 39 9 0.230769230769231 0.00661764705882353
TF TF:M00444_1 Factor: VDR; motif: GGGKNARNRRGGWSA; match class: 1 0.0462247464466905 4534 33 16 0.484848484848485 0.0035288928098809
TF TF:M01588 Factor: GKLF; motif: GCCMCRCCCNNN 0.0462247464466905 8944 12 11 0.916666666666667 0.0012298747763864
TF TF:M00924 Factor: AP-1; motif: TGACTCANNSKN 0.0462247464466905 2801 37 13 0.351351351351351 0.00464119957158158
TF TF:M00053 Factor: c-Rel; motif: SGGRNTTTCC 0.0466472702094921 3672 58 21 0.362068965517241 0.00571895424836601
TF TF:M11445 Factor: Elf-1; motif: NANCAGGAAGTR 0.0470679934088435 1689 52 12 0.230769230769231 0.00710479573712256
TF TF:M11240 Factor: OASIS; motif: NTGCCACGTGKNCN 0.0470679934088435 42 99 3 0.0303030303030303 0.0714285714285714
TF TF:M00800_1 Factor: AP-2; motif: GSCCSCRGGCNRNRNN; match class: 1 0.0470679934088435 4268 92 33 0.358695652173913 0.0077319587628866
TF TF:M00495 Factor: Bach1; motif: NNSATGAGTCATGNT 0.0478740429230757 478 34 5 0.147058823529412 0.0104602510460251
TF TF:M00933_1 Factor: Sp1; motif: CCCCGCCCCN; match class: 1 0.0478740429230757 5166 142 54 0.380281690140845 0.0104529616724739
TF TF:M09957 Factor: IRF-2; motif: NAAANNGAAAGTGAAASTRN 0.0478740429230757 272 118 7 0.0593220338983051 0.0257352941176471
TF TF:M10008_1 Factor: CSX; motif: NKRAGWGS; match class: 1 0.0478740429230757 3963 13 8 0.615384615384615 0.00201867272268483
TF TF:M09763 Factor: NF1C; motif: WGCCARR 0.0478740429230757 10866 82 59 0.719512195121951 0.00542978096815756
TF TF:M08955 Factor: FXR:RXR-ALPHA; motif: NRGGTCANRGGKN 0.0482410922443838 9729 31 24 0.774193548387097 0.00246685168054271
TF TF:M12352_1 Factor: ZBTB44; motif: MACWGCAGS; match class: 1 0.0482410922443838 1367 128 19 0.1484375 0.013899049012436
TF TF:M11073 Factor: DEC1; motif: GTCACGTGAC 0.0487396139654502 6583 82 41 0.5 0.00622816345131399
TF TF:M05528 Factor: ZAC; motif: KGWTGGGSAT 0.0487396139654502 147 64 4 0.0625 0.0272108843537415
TF TF:M07087_1 Factor: Elf-1; motif: NRANCMGGAAGTG; match class: 1 0.0490241186644404 155 28 3 0.107142857142857 0.0193548387096774
TF TF:M03567_1 Factor: Sp2; motif: NYSGCCCCGCCCCCY; match class: 1 0.049713704970551 3614 142 41 0.288732394366197 0.0113447703375761
WP WP:WP619 Type II interferon signaling (IFNG) 0.0218969499608705 37 98 5 0.0510204081632653 0.135135135135135

pB01 transcription factor target enrichment of top program genes

TF enrichment of pB01
TFs corrosponding to activation of pB01. (Left) pearson correlation of TF expression and gene expression program activatity in B cells, (right) negative log p-value for enrichment of TF binding sites among top uniqueness weighted genes for the gene program. Blue bars indicate significant TFs meeting the following criteria: FDR<0.1, overlap > 2, Corr. R > 0, permutation based p-value < 0.05.