pTNI01 program activity among T/NK/ILC cells

Activation of pTNI01
pTNI01 gene program activation in T/NK/ILC cells.
Gene program activation of pTNI01 by different cell subtypes
pTNI01 gene program activation among cells of different subtypes (T/NK/ILC cells).

pTNI01 top program genes

Top genes of pTNI01 program
Bar plots showing the top genes for each gene program, ranked by (left) unique weights, (right) raw weights.

pTNI01 gene-set enrichment of top program genes (using g-profiler)

GSEA wth gene profiler of pTNI01
pTNI01 gene-set enrichment summary using g-profiler webtool.
Source termID Name Padj Tsize Qsize Overlap Precision Recall
GO:BP GO:0045944 positive regulation of transcription by RNA polymerase II 6.66609592975549e-07 1197 29 14 0.482758620689655 0.0116959064327485
GO:BP GO:0006366 transcription by RNA polymerase II 6.66609592975549e-07 2723 29 19 0.655172413793103 0.00697759823723834
GO:BP GO:0051254 positive regulation of RNA metabolic process 6.66609592975549e-07 1714 29 16 0.551724137931034 0.00933488914819136
GO:BP GO:0006357 regulation of transcription by RNA polymerase II 1.41187278233714e-06 2555 29 18 0.620689655172414 0.00704500978473581
GO:BP GO:0045935 positive regulation of nucleobase-containing compound metabolic process 1.41187278233714e-06 1887 29 16 0.551724137931034 0.00847906730259671
GO:BP GO:0034654 nucleobase-containing compound biosynthetic process 4.25696215776759e-06 4199 29 21 0.724137931034483 0.00500119075970469
GO:BP GO:0097659 nucleic acid-templated transcription 4.25696215776759e-06 3715 29 20 0.689655172413793 0.0053835800807537
GO:BP GO:0006351 transcription, DNA-templated 4.25696215776759e-06 3714 29 20 0.689655172413793 0.0053850296176629
GO:BP GO:0035914 skeletal muscle cell differentiation 4.25696215776759e-06 68 46 6 0.130434782608696 0.0882352941176471
GO:BP GO:0010556 regulation of macromolecule biosynthetic process 4.25696215776759e-06 4102 29 21 0.724137931034483 0.00511945392491468
GO:BP GO:0010557 positive regulation of macromolecule biosynthetic process 4.25696215776759e-06 1851 29 15 0.517241379310345 0.00810372771474878
GO:BP GO:0032774 RNA biosynthetic process 4.25696215776759e-06 3731 29 20 0.689655172413793 0.00536049316537121
GO:BP GO:2000112 regulation of cellular macromolecule biosynthetic process 4.25696215776759e-06 4071 29 21 0.724137931034483 0.0051584377302874
GO:BP GO:0031326 regulation of cellular biosynthetic process 4.61462117684036e-06 4273 29 21 0.724137931034483 0.00491457992043061
GO:BP GO:0018130 heterocycle biosynthetic process 4.61462117684036e-06 4269 29 21 0.724137931034483 0.00491918482080112
GO:BP GO:0045893 positive regulation of transcription, DNA-templated 4.61462117684036e-06 1617 29 14 0.482758620689655 0.00865800865800866
GO:BP GO:1902680 positive regulation of RNA biosynthetic process 4.61462117684036e-06 1618 29 14 0.482758620689655 0.00865265760197775
GO:BP GO:0019438 aromatic compound biosynthetic process 4.61462117684036e-06 4278 29 21 0.724137931034483 0.00490883590462833
GO:BP GO:1903508 positive regulation of nucleic acid-templated transcription 4.61462117684036e-06 1617 29 14 0.482758620689655 0.00865800865800866
GO:BP GO:0010467 gene expression 4.69780267309818e-06 6179 48 35 0.729166666666667 0.00566434698171225
GO:BP GO:0009889 regulation of biosynthetic process 5.35548058853324e-06 4361 29 21 0.724137931034483 0.00481540930979133
GO:BP GO:0031328 positive regulation of cellular biosynthetic process 5.494854808623e-06 1967 29 15 0.517241379310345 0.00762582613116421
GO:BP GO:1901362 organic cyclic compound biosynthetic process 6.26103950036097e-06 4439 29 21 0.724137931034483 0.00473079522414958
GO:BP GO:0009891 positive regulation of biosynthetic process 6.26103950036097e-06 2004 29 15 0.517241379310345 0.00748502994011976
GO:BP GO:0051173 positive regulation of nitrogen compound metabolic process 6.26103950036097e-06 3083 29 18 0.620689655172414 0.00583846902367824
GO:BP GO:0006355 regulation of transcription, DNA-templated 6.36558290935939e-06 3534 29 19 0.655172413793103 0.00537634408602151
GO:BP GO:2001141 regulation of RNA biosynthetic process 6.36558290935939e-06 3540 29 19 0.655172413793103 0.00536723163841808
GO:BP GO:1903506 regulation of nucleic acid-templated transcription 6.36558290935939e-06 3535 29 19 0.655172413793103 0.00537482319660538
GO:BP GO:0044271 cellular nitrogen compound biosynthetic process 6.95555511308987e-06 5017 29 22 0.758620689655172 0.0043850906916484
GO:BP GO:0034645 cellular macromolecule biosynthetic process 7.67158311503777e-06 5051 29 22 0.758620689655172 0.00435557315383092
GO:BP GO:0019219 regulation of nucleobase-containing compound metabolic process 8.88070635309093e-06 4091 29 20 0.689655172413793 0.00488878024932779
GO:BP GO:0051384 response to glucocorticoid 8.88070635309093e-06 146 7 4 0.571428571428571 0.0273972602739726
GO:BP GO:0009059 macromolecule biosynthetic process 8.88070635309093e-06 5114 29 22 0.758620689655172 0.00430191630817364
GO:BP GO:0051592 response to calcium ion 9.86938081384539e-06 151 7 4 0.571428571428571 0.0264900662251656
GO:BP GO:0031325 positive regulation of cellular metabolic process 1.09176937091055e-05 3274 29 18 0.620689655172414 0.00549786194257789
GO:BP GO:0010468 regulation of gene expression 1.10907880953216e-05 5196 29 22 0.758620689655172 0.00423402617397998
GO:BP GO:0006915 apoptotic process 1.14195093969179e-05 1990 43 18 0.418604651162791 0.00904522613065327
GO:BP GO:0009612 response to mechanical stimulus 1.14195093969179e-05 218 36 7 0.194444444444444 0.0321100917431193
GO:BP GO:0090304 nucleic acid metabolic process 1.14476088086868e-05 5226 29 22 0.758620689655172 0.00420972062763108
GO:BP GO:0031960 response to corticosteroid 1.16866079330891e-05 165 7 4 0.571428571428571 0.0242424242424242
GO:BP GO:0016070 RNA metabolic process 1.16866079330891e-05 4710 29 21 0.724137931034483 0.00445859872611465
GO:BP GO:0051252 regulation of RNA metabolic process 1.52308683142521e-05 3822 29 19 0.655172413793103 0.00497121925693354
GO:BP GO:0008219 cell death 1.53704939479175e-05 2292 43 19 0.441860465116279 0.00828970331588133
GO:BP GO:0010941 regulation of cell death 2.22742487122257e-05 1720 28 13 0.464285714285714 0.00755813953488372
GO:BP GO:0010604 positive regulation of macromolecule metabolic process 2.24395856706486e-05 3483 29 18 0.620689655172414 0.00516795865633075
GO:BP GO:0012501 programmed cell death 2.85618681954446e-05 2143 43 18 0.418604651162791 0.00839944003733084
GO:BP GO:0033554 cellular response to stress 2.9851259491123e-05 2111 28 14 0.5 0.00663192799621033
GO:BP GO:0031323 regulation of cellular metabolic process 4.60737789577506e-05 6269 29 23 0.793103448275862 0.00366884670601372
GO:BP GO:0042981 regulation of apoptotic process 5.01531713425151e-05 1549 59 18 0.305084745762712 0.0116204002582311
GO:BP GO:0009628 response to abiotic stimulus 5.33528590906216e-05 1261 28 11 0.392857142857143 0.00872323552735924
GO:BP GO:0006139 nucleobase-containing compound metabolic process 5.41438007012059e-05 5746 29 22 0.758620689655172 0.00382875043508528
GO:BP GO:0048522 positive regulation of cellular process 5.50688000278414e-05 5757 29 22 0.758620689655172 0.00382143477505645
GO:BP GO:0002520 immune system development 5.94323972297557e-05 1020 17 8 0.470588235294118 0.00784313725490196
GO:BP GO:0043067 regulation of programmed cell death 5.94323972297557e-05 1582 28 12 0.428571428571429 0.00758533501896334
GO:BP GO:0014070 response to organic cyclic compound 6.27995270313719e-05 967 9 6 0.666666666666667 0.0062047569803516
GO:BP GO:0010033 response to organic substance 6.27995270313719e-05 3412 16 12 0.75 0.00351699882766706
GO:BP GO:0009893 positive regulation of metabolic process 6.36822808094337e-05 3783 29 18 0.620689655172414 0.00475812846946868
GO:BP GO:0051171 regulation of nitrogen compound metabolic process 6.63587887166986e-05 5848 29 22 0.758620689655172 0.00376196990424077
GO:BP GO:0071345 cellular response to cytokine stimulus 6.63587887166986e-05 1132 16 8 0.5 0.00706713780918728
GO:BP GO:0046483 heterocycle metabolic process 7.60150554431049e-05 5904 29 22 0.758620689655172 0.00372628726287263
GO:BP GO:0019222 regulation of metabolic process 7.60150554431049e-05 7148 29 24 0.827586206896552 0.00335758254057079
GO:BP GO:0034641 cellular nitrogen compound metabolic process 8.77037724753296e-05 6563 29 23 0.793103448275862 0.003504494895627
GO:BP GO:0006725 cellular aromatic compound metabolic process 8.77037724753296e-05 5956 29 22 0.758620689655172 0.00369375419744795
GO:BP GO:0007519 skeletal muscle tissue development 9.50500163263405e-05 160 46 6 0.130434782608696 0.0375
GO:BP GO:0060255 regulation of macromolecule metabolic process 9.50500163263405e-05 6603 29 23 0.793103448275862 0.00348326518249281
GO:BP GO:0002521 leukocyte differentiation 9.50500163263405e-05 550 41 9 0.219512195121951 0.0163636363636364
GO:BP GO:0033993 response to lipid 9.50500163263405e-05 918 10 6 0.6 0.0065359477124183
GO:BP GO:0071277 cellular response to calcium ion 0.000102938953130758 84 7 3 0.428571428571429 0.0357142857142857
GO:BP GO:0034097 response to cytokine 0.000103506701671885 1226 16 8 0.5 0.0065252854812398
GO:BP GO:0080090 regulation of primary metabolic process 0.000105489032532205 6053 29 22 0.758620689655172 0.00363456137452503
GO:BP GO:0060538 skeletal muscle organ development 0.000125568003769599 170 46 6 0.130434782608696 0.0352941176470588
GO:BP GO:0048545 response to steroid hormone 0.000130686612758931 349 7 4 0.571428571428571 0.0114613180515759
GO:BP GO:0030097 hemopoiesis 0.000131013314913761 928 41 11 0.268292682926829 0.0118534482758621
GO:BP GO:0044249 cellular biosynthetic process 0.000134247996994825 6154 29 22 0.758620689655172 0.00357491062723432
GO:BP GO:0051591 response to cAMP 0.00014221080129102 97 7 3 0.428571428571429 0.0309278350515464
GO:BP GO:1901360 organic cyclic compound metabolic process 0.000150728871594399 6201 29 22 0.758620689655172 0.00354781486856959
GO:BP GO:0010038 response to metal ion 0.000155888618923702 371 7 4 0.571428571428571 0.0107816711590297
GO:BP GO:1901576 organic substance biosynthetic process 0.000165905528623332 6248 29 22 0.758620689655172 0.00352112676056338
GO:BP GO:0009725 response to hormone 0.000165905528623332 921 28 9 0.321428571428571 0.00977198697068404
GO:BP GO:0043066 negative regulation of apoptotic process 0.000165905528623332 921 59 13 0.220338983050847 0.0141150922909881
GO:BP GO:0070887 cellular response to chemical stimulus 0.000171468110195028 3393 28 16 0.571428571428571 0.00471559092248747
GO:BP GO:0048534 hematopoietic or lymphoid organ development 0.000171468110195028 966 41 11 0.268292682926829 0.0113871635610766
GO:BP GO:1901700 response to oxygen-containing compound 0.000172116630442566 1739 10 7 0.7 0.00402530189764232
GO:BP GO:0010035 response to inorganic substance 0.000173301993316039 575 10 5 0.5 0.00869565217391304
GO:BP GO:0010243 response to organonitrogen compound 0.000187962943798083 1085 10 6 0.6 0.00552995391705069
GO:BP GO:0043069 negative regulation of programmed cell death 0.000196970747030965 943 59 13 0.220338983050847 0.0137857900318134
GO:BP GO:0009058 biosynthetic process 0.000196970747030965 6340 29 22 0.758620689655172 0.00347003154574133
GO:BP GO:0048518 positive regulation of biological process 0.000208305945715881 6363 29 22 0.758620689655172 0.00345748860600346
GO:BP GO:1901698 response to nitrogen compound 0.000277786835858372 1172 10 6 0.6 0.00511945392491468
GO:BP GO:0007050 cell cycle arrest 0.000310185154208278 241 40 6 0.15 0.024896265560166
GO:BP GO:0046683 response to organophosphorus 0.000324755743141808 137 7 3 0.428571428571429 0.0218978102189781
GO:BP GO:0014074 response to purine-containing compound 0.000438728243887326 152 7 3 0.428571428571429 0.0197368421052632
GO:BP GO:0014706 striated muscle tissue development 0.000458071826975536 380 28 6 0.214285714285714 0.0157894736842105
GO:BP GO:0060548 negative regulation of cell death 0.000474897528483634 1038 43 11 0.255813953488372 0.010597302504817
GO:BP GO:0032496 response to lipopolysaccharide 0.000490830448570946 338 10 4 0.4 0.0118343195266272
GO:BP GO:0071310 cellular response to organic substance 0.000490830448570946 2776 16 10 0.625 0.00360230547550432
GO:BP GO:0060537 muscle tissue development 0.000573011310420698 399 28 6 0.214285714285714 0.0150375939849624
GO:BP GO:0042221 response to chemical 0.000588284369885456 4781 28 18 0.642857142857143 0.00376490274001255
GO:BP GO:0002237 response to molecule of bacterial origin 0.000606023557487856 361 10 4 0.4 0.0110803324099723
GO:BP GO:0030154 cell differentiation 0.000678616737508988 4350 38 21 0.552631578947368 0.00482758620689655
GO:BP GO:0048585 negative regulation of response to stimulus 0.000681232612368937 1733 24 10 0.416666666666667 0.00577034045008656
GO:BP GO:0009968 negative regulation of signal transduction 0.000681232612368937 1364 24 9 0.375 0.00659824046920821
GO:BP GO:0030099 myeloid cell differentiation 0.000681232612368937 428 9 4 0.444444444444444 0.00934579439252336
GO:BP GO:0002376 immune system process 0.000685384062338732 3278 20 12 0.6 0.0036607687614399
GO:BP GO:0071248 cellular response to metal ion 0.000754882227093236 192 7 3 0.428571428571429 0.015625
GO:BP GO:0051726 regulation of cell cycle 0.000782291796336858 1236 53 13 0.245283018867925 0.0105177993527508
GO:BP GO:0006979 response to oxidative stress 0.000782291796336858 466 26 6 0.230769230769231 0.0128755364806867
GO:BP GO:0019221 cytokine-mediated signaling pathway 0.000789430849682419 810 16 6 0.375 0.00740740740740741
GO:BP GO:0007565 female pregnancy 0.00079867351973153 198 7 3 0.428571428571429 0.0151515151515152
GO:BP GO:0048869 cellular developmental process 0.000816452885056663 4428 38 21 0.552631578947368 0.00474254742547425
GO:BP GO:1901654 response to ketone 0.000858098060646204 204 7 3 0.428571428571429 0.0147058823529412
GO:BP GO:0000122 negative regulation of transcription by RNA polymerase II 0.000863546234256101 901 53 11 0.207547169811321 0.0122086570477248
GO:BP GO:0032870 cellular response to hormone stimulus 0.000905749430680849 645 7 4 0.571428571428571 0.0062015503875969
GO:BP GO:1901214 regulation of neuron death 0.000970632398307932 323 24 5 0.208333333333333 0.0154798761609907
GO:BP GO:0071241 cellular response to inorganic substance 0.00101388315416896 220 7 3 0.428571428571429 0.0136363636363636
GO:BP GO:0044260 cellular macromolecule metabolic process 0.00101388315416896 8390 29 24 0.827586206896552 0.00286054827175209
GO:BP GO:0010648 negative regulation of cell communication 0.00104781309638975 1468 24 9 0.375 0.0061307901907357
GO:BP GO:0023057 negative regulation of signaling 0.00105637409305203 1471 24 9 0.375 0.00611828687967369
GO:BP GO:0044706 multi-multicellular organism process 0.00107816674927231 227 7 3 0.428571428571429 0.013215859030837
GO:BP GO:0034599 cellular response to oxidative stress 0.00123455054638803 316 26 5 0.192307692307692 0.0158227848101266
GO:BP GO:1901216 positive regulation of neuron death 0.00131415831916748 98 16 3 0.1875 0.0306122448979592
GO:BP GO:0008283 cell population proliferation 0.00144910617470568 2054 36 13 0.361111111111111 0.00632911392405063
GO:BP GO:0070997 neuron death 0.00156324178046063 365 24 5 0.208333333333333 0.0136986301369863
GO:BP GO:0007517 muscle organ development 0.00156324178046063 333 59 7 0.11864406779661 0.021021021021021
GO:BP GO:0006950 response to stress 0.00157183536840906 4170 28 16 0.571428571428571 0.00383693045563549
GO:BP GO:0048856 anatomical structure development 0.00166737630125033 6106 29 20 0.689655172413793 0.00327546675401245
GO:BP GO:0009888 tissue development 0.00170461998787206 2107 6 5 0.833333333333333 0.00237304224015187
GO:BP GO:0009719 response to endogenous stimulus 0.00178922032141492 1683 7 5 0.714285714285714 0.0029708853238265
GO:BP GO:0007275 multicellular organism development 0.00188959613670054 5613 29 19 0.655172413793103 0.00338499910921076
GO:BP GO:1901652 response to peptide 0.00188959613670054 551 27 6 0.222222222222222 0.0108892921960073
GO:BP GO:0032269 negative regulation of cellular protein metabolic process 0.00198559834861237 1082 15 6 0.4 0.0055452865064695
GO:BP GO:0062197 cellular response to chemical stress 0.00209689031884593 365 26 5 0.192307692307692 0.0136986301369863
GO:BP GO:0071222 cellular response to lipopolysaccharide 0.00209689031884593 200 10 3 0.3 0.015
GO:BP GO:0048513 animal organ development 0.00217875550645723 3672 54 23 0.425925925925926 0.0062636165577342
GO:BP GO:0031324 negative regulation of cellular metabolic process 0.00218390050091271 2719 16 9 0.5625 0.00331004045605002
GO:BP GO:0010942 positive regulation of cell death 0.00224271590102949 684 23 6 0.260869565217391 0.0087719298245614
GO:BP GO:0000302 response to reactive oxygen species 0.00224755869822417 237 40 5 0.125 0.0210970464135021
GO:BP GO:0009605 response to external stimulus 0.00237859344560811 2944 28 13 0.464285714285714 0.00441576086956522
GO:BP GO:2000113 negative regulation of cellular macromolecule biosynthetic process 0.00237859344560811 1628 53 14 0.264150943396226 0.0085995085995086
GO:BP GO:0071219 cellular response to molecule of bacterial origin 0.0024017978041554 214 10 3 0.3 0.014018691588785
GO:BP GO:0002682 regulation of immune system process 0.00242077288073284 1617 20 8 0.4 0.00494743351886209
GO:BP GO:0030098 lymphocyte differentiation 0.00242077288073284 376 41 6 0.146341463414634 0.0159574468085106
GO:BP GO:0010558 negative regulation of macromolecule biosynthetic process 0.0024385167836665 1639 53 14 0.264150943396226 0.00854179377669311
GO:BP GO:0080134 regulation of response to stress 0.0024385167836665 1443 17 7 0.411764705882353 0.00485100485100485
GO:BP GO:0042127 regulation of cell population proliferation 0.00250107700818665 1774 28 10 0.357142857142857 0.0056369785794814
GO:BP GO:0051248 negative regulation of protein metabolic process 0.00250107700818665 1151 15 6 0.4 0.0052128583840139
GO:BP GO:1903706 regulation of hemopoiesis 0.00250107700818665 424 37 6 0.162162162162162 0.0141509433962264
GO:BP GO:1904035 regulation of epithelial cell apoptotic process 0.00250366108575535 105 20 3 0.15 0.0285714285714286
GO:BP GO:0051172 negative regulation of nitrogen compound metabolic process 0.00282424228413918 2518 54 18 0.333333333333333 0.00714853057982526
GO:BP GO:0045597 positive regulation of cell differentiation 0.0028462250986664 879 27 7 0.259259259259259 0.00796359499431172
GO:BP GO:0045637 regulation of myeloid cell differentiation 0.00288506886181234 263 9 3 0.333333333333333 0.0114068441064639
GO:BP GO:0071216 cellular response to biotic stimulus 0.00300552100947493 238 10 3 0.3 0.0126050420168067
GO:BP GO:0022407 regulation of cell-cell adhesion 0.00306362772523814 445 37 6 0.162162162162162 0.0134831460674157
GO:BP GO:0043170 macromolecule metabolic process 0.00313840488078835 9796 29 25 0.862068965517241 0.00255206206614945
GO:BP GO:0006977 DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest 0.00329374923954786 58 40 3 0.075 0.0517241379310345
GO:BP GO:0031327 negative regulation of cellular biosynthetic process 0.00337541540890652 1707 53 14 0.264150943396226 0.00820152314001172
GO:BP GO:1902400 intracellular signal transduction involved in G1 DNA damage checkpoint 0.0034084083379604 59 40 3 0.075 0.0508474576271186
GO:BP GO:0072431 signal transduction involved in mitotic G1 DNA damage checkpoint 0.0034084083379604 59 40 3 0.075 0.0508474576271186
GO:BP GO:1902403 signal transduction involved in mitotic DNA integrity checkpoint 0.00367436225934884 61 40 3 0.075 0.0491803278688525
GO:BP GO:1902402 signal transduction involved in mitotic DNA damage checkpoint 0.00367436225934884 61 40 3 0.075 0.0491803278688525
GO:BP GO:0009890 negative regulation of biosynthetic process 0.00387942238275203 1740 53 14 0.264150943396226 0.00804597701149425
GO:BP GO:0072413 signal transduction involved in mitotic cell cycle checkpoint 0.00390202502593763 63 40 3 0.075 0.0476190476190476
GO:BP GO:0002819 regulation of adaptive immune response 0.00390202502593763 167 37 4 0.108108108108108 0.0239520958083832
GO:BP GO:1904019 epithelial cell apoptotic process 0.00390202502593763 128 20 3 0.15 0.0234375
GO:BP GO:0050727 regulation of inflammatory response 0.00394642142629064 381 17 4 0.235294117647059 0.010498687664042
GO:BP GO:0048583 regulation of response to stimulus 0.00402679266121906 4278 41 20 0.48780487804878 0.00467508181393174
GO:BP GO:1903131 mononuclear cell differentiation 0.00402679266121906 430 41 6 0.146341463414634 0.013953488372093
GO:BP GO:0061061 muscle structure development 0.00402679266121906 645 28 6 0.214285714285714 0.00930232558139535
GO:BP GO:0045892 negative regulation of transcription, DNA-templated 0.00404697601611721 1337 53 12 0.226415094339623 0.00897531787584144
GO:BP GO:1903507 negative regulation of nucleic acid-templated transcription 0.00408227333393366 1339 53 12 0.226415094339623 0.00896191187453323
GO:BP GO:1902679 negative regulation of RNA biosynthetic process 0.00409777898432781 1341 53 12 0.226415094339623 0.00894854586129754
GO:BP GO:0032502 developmental process 0.00409777898432781 6628 29 20 0.689655172413793 0.00301750150875075
GO:BP GO:0045934 negative regulation of nucleobase-containing compound metabolic process 0.00412384312869907 1548 53 13 0.245283018867925 0.00839793281653747
GO:BP GO:0031571 mitotic G1 DNA damage checkpoint 0.0041921085339094 66 40 3 0.075 0.0454545454545455
GO:BP GO:0044819 mitotic G1/S transition checkpoint 0.00432669709226996 67 40 3 0.075 0.0447761194029851
GO:BP GO:0044783 G1 DNA damage checkpoint 0.00432669709226996 67 40 3 0.075 0.0447761194029851
GO:BP GO:0007093 mitotic cell cycle checkpoint 0.00456274265906335 164 40 4 0.1 0.024390243902439
GO:BP GO:0045786 negative regulation of cell cycle 0.00473715734664052 647 40 7 0.175 0.0108191653786708
GO:BP GO:0009617 response to bacterium 0.00476156232612905 743 10 4 0.4 0.0053835800807537
GO:BP GO:0071356 cellular response to tumor necrosis factor 0.00510981521002806 306 10 3 0.3 0.00980392156862745
GO:BP GO:1902532 negative regulation of intracellular signal transduction 0.0051664273908072 549 23 5 0.217391304347826 0.00910746812386157
GO:BP GO:0051348 negative regulation of transferase activity 0.00519441093211865 310 10 3 0.3 0.00967741935483871
GO:BP GO:0022414 reproductive process 0.0052169658623904 1493 3 3 1 0.00200937709310114
GO:BP GO:0000003 reproduction 0.00521892671307965 1496 3 3 1 0.00200534759358289
GO:BP GO:0048872 homeostasis of number of cells 0.0054365220344566 261 12 3 0.25 0.0114942528735632
GO:BP GO:0072422 signal transduction involved in DNA damage checkpoint 0.00550307727099499 75 40 3 0.075 0.04
GO:BP GO:0072401 signal transduction involved in DNA integrity checkpoint 0.00550307727099499 75 40 3 0.075 0.04
GO:BP GO:0006954 inflammatory response 0.00563065387297894 794 10 4 0.4 0.00503778337531486
GO:BP GO:0048523 negative regulation of cellular process 0.00563065387297894 5139 54 27 0.5 0.00525394045534151
GO:BP GO:2000026 regulation of multicellular organismal development 0.00572919856116014 1447 59 13 0.220338983050847 0.00898410504492052
GO:BP GO:0009892 negative regulation of metabolic process 0.00579016612330165 3479 24 12 0.5 0.00344926703075596
GO:BP GO:0030155 regulation of cell adhesion 0.00579016612330165 748 59 9 0.152542372881356 0.0120320855614973
GO:BP GO:0034612 response to tumor necrosis factor 0.00579016612330165 331 10 3 0.3 0.00906344410876133
GO:BP GO:0032268 regulation of cellular protein metabolic process 0.00579016612330165 2541 16 8 0.5 0.00314836678473042
GO:BP GO:0043618 regulation of transcription from RNA polymerase II promoter in response to stress 0.00579016612330165 111 28 3 0.107142857142857 0.027027027027027
GO:BP GO:0072395 signal transduction involved in cell cycle checkpoint 0.0058657795644161 78 40 3 0.075 0.0384615384615385
GO:BP GO:0035556 intracellular signal transduction 0.00598127715136829 2772 15 8 0.533333333333333 0.00288600288600289
GO:BP GO:0051094 positive regulation of developmental process 0.00612160119889562 1341 28 8 0.285714285714286 0.00596569724086503
GO:BP GO:0043620 regulation of DNA-templated transcription in response to stress 0.00644510527824728 117 28 3 0.107142857142857 0.0256410256410256
GO:BP GO:0051253 negative regulation of RNA metabolic process 0.0065486917606331 1445 53 12 0.226415094339623 0.00830449826989619
GO:BP GO:0045936 negative regulation of phosphate metabolic process 0.00692028133537996 543 15 4 0.266666666666667 0.00736648250460405
GO:BP GO:0010563 negative regulation of phosphorus metabolic process 0.00694089083109488 544 15 4 0.266666666666667 0.00735294117647059
GO:BP GO:0030522 intracellular receptor signaling pathway 0.00732286326925637 284 28 4 0.142857142857143 0.0140845070422535
GO:BP GO:0071158 positive regulation of cell cycle arrest 0.00767154871848866 88 40 3 0.075 0.0340909090909091
GO:BP GO:0097190 apoptotic signaling pathway 0.0077552742547114 600 24 5 0.208333333333333 0.00833333333333333
GO:BP GO:0051246 regulation of protein metabolic process 0.00791497651895923 2704 16 8 0.5 0.0029585798816568
GO:BP GO:0071901 negative regulation of protein serine/threonine kinase activity 0.00799311040557681 150 54 4 0.0740740740740741 0.0266666666666667
GO:BP GO:2001236 regulation of extrinsic apoptotic signaling pathway 0.00799311040557681 159 23 3 0.130434782608696 0.0188679245283019
GO:BP GO:0031400 negative regulation of protein modification process 0.00813257291587812 578 15 4 0.266666666666667 0.0069204152249135
GO:BP GO:0071495 cellular response to endogenous stimulus 0.00825211382123731 1422 7 4 0.571428571428571 0.00281293952180028
GO:BP GO:0031331 positive regulation of cellular catabolic process 0.00825211382123731 393 10 3 0.3 0.00763358778625954
GO:BP GO:0050896 response to stimulus 0.00830503350027164 9407 18 16 0.888888888888889 0.00170086106091209
GO:BP GO:0046634 regulation of alpha-beta T cell activation 0.0086954339835546 102 37 3 0.0810810810810811 0.0294117647058824
GO:BP GO:0032102 negative regulation of response to external stimulus 0.00881855647182406 406 10 3 0.3 0.00738916256157635
GO:BP GO:0071456 cellular response to hypoxia 0.00882630417172649 212 40 4 0.1 0.0188679245283019
GO:BP GO:0001666 response to hypoxia 0.00895717884223074 367 40 5 0.125 0.0136239782016349
GO:BP GO:2001233 regulation of apoptotic signaling pathway 0.00897626538511511 363 24 4 0.166666666666667 0.0110192837465565
GO:BP GO:0042542 response to hydrogen peroxide 0.00914248700031804 150 26 3 0.115384615384615 0.02
GO:BP GO:0000075 cell cycle checkpoint 0.00929401160495163 216 40 4 0.1 0.0185185185185185
GO:BP GO:1901701 cellular response to oxygen-containing compound 0.00970151319705866 1227 26 7 0.269230769230769 0.00570497147514262
GO:BP GO:2000045 regulation of G1/S transition of mitotic cell cycle 0.00973703289185935 182 48 4 0.0833333333333333 0.021978021978022
GO:BP GO:0032501 multicellular organismal process 0.00975498943719581 7946 17 14 0.823529411764706 0.00176189277623962
GO:BP GO:0043414 macromolecule methylation 0.00975498943719581 312 48 5 0.104166666666667 0.016025641025641
GO:BP GO:0051090 regulation of DNA-binding transcription factor activity 0.00985426939435315 456 20 4 0.2 0.0087719298245614
GO:BP GO:0006259 DNA metabolic process 0.00985426939435315 965 5 3 0.6 0.00310880829015544
GO:BP GO:0036294 cellular response to decreased oxygen levels 0.0100052149872594 222 40 4 0.1 0.018018018018018
GO:BP GO:0036293 response to decreased oxygen levels 0.010162816269835 382 40 5 0.125 0.0130890052356021
GO:BP GO:0001775 cell activation 0.0102902539439572 1495 41 10 0.24390243902439 0.00668896321070234
GO:BP GO:0010605 negative regulation of macromolecule metabolic process 0.0102902539439572 3241 24 11 0.458333333333333 0.00339401419315026
GO:BP GO:0045580 regulation of T cell differentiation 0.0104358903979615 152 59 4 0.0677966101694915 0.0263157894736842
GO:BP GO:0045595 regulation of cell differentiation 0.0104384138445814 1679 20 7 0.35 0.00416914830256105
GO:BP GO:0046649 lymphocyte activation 0.0106045506640027 771 41 7 0.170731707317073 0.00907911802853437
GO:BP GO:0030217 T cell differentiation 0.0106045506640027 260 59 5 0.0847457627118644 0.0192307692307692
GO:BP GO:0046632 alpha-beta T cell differentiation 0.010628197000601 113 37 3 0.0810810810810811 0.0265486725663717
GO:BP GO:0044773 mitotic DNA damage checkpoint 0.0108700790211817 106 40 3 0.075 0.0283018867924528
GO:BP GO:1902107 positive regulation of leukocyte differentiation 0.0111325356422803 157 59 4 0.0677966101694915 0.0254777070063694
GO:BP GO:1903708 positive regulation of hemopoiesis 0.0111325356422803 157 59 4 0.0677966101694915 0.0254777070063694
GO:BP GO:0009896 positive regulation of catabolic process 0.0113516882809163 464 10 3 0.3 0.00646551724137931
GO:BP GO:0048731 system development 0.0114208648380208 5052 29 16 0.551724137931034 0.00316706254948535
GO:BP GO:0032101 regulation of response to external stimulus 0.0114208648380208 1051 10 4 0.4 0.00380589914367269
GO:BP GO:0034614 cellular response to reactive oxygen species 0.0114681145389094 170 26 3 0.115384615384615 0.0176470588235294
GO:BP GO:0070373 negative regulation of ERK1 and ERK2 cascade 0.0115063238532207 81 54 3 0.0555555555555556 0.037037037037037
GO:BP GO:0030330 DNA damage response, signal transduction by p53 class mediator 0.0115670321983229 110 40 3 0.075 0.0272727272727273
GO:BP GO:0097191 extrinsic apoptotic signaling pathway 0.0118767550608914 223 43 4 0.0930232558139535 0.0179372197309417
GO:BP GO:0071453 cellular response to oxygen levels 0.0118767550608914 240 40 4 0.1 0.0166666666666667
GO:BP GO:0044774 mitotic DNA integrity checkpoint 0.0120338363032488 112 40 3 0.075 0.0267857142857143
GO:BP GO:0070482 response to oxygen levels 0.0120467586617256 408 40 5 0.125 0.0122549019607843
GO:BP GO:0006807 nitrogen compound metabolic process 0.0122703666427193 10078 29 24 0.827586206896552 0.00238142488589006
GO:BP GO:0007568 aging 0.0123762025256676 329 50 5 0.1 0.0151975683890578
GO:BP GO:0071156 regulation of cell cycle arrest 0.0123762025256676 115 40 3 0.075 0.0260869565217391
GO:BP GO:1902806 regulation of cell cycle G1/S phase transition 0.0126495113581464 206 48 4 0.0833333333333333 0.0194174757281553
GO:BP GO:0044237 cellular metabolic process 0.012681722602658 10871 29 25 0.862068965517241 0.00229969644006991
GO:BP GO:0007049 cell cycle 0.012681722602658 1902 40 11 0.275 0.00578338590956887
GO:BP GO:0007422 peripheral nervous system development 0.012681722602658 79 59 3 0.0508474576271186 0.0379746835443038
GO:BP GO:0007369 gastrulation 0.0130889835227018 185 26 3 0.115384615384615 0.0162162162162162
GO:BP GO:0002683 negative regulation of immune system process 0.0131605808335681 420 12 3 0.25 0.00714285714285714
GO:BP GO:0044092 negative regulation of molecular function 0.0131605808335681 1219 15 5 0.333333333333333 0.00410172272354389
GO:BP GO:0051704 multi-organism process 0.0133634513719486 1135 10 4 0.4 0.00352422907488987
GO:BP GO:1902105 regulation of leukocyte differentiation 0.0136556304508389 288 59 5 0.0847457627118644 0.0173611111111111
GO:BP GO:0045321 leukocyte activation 0.0137591800114454 1332 41 9 0.219512195121951 0.00675675675675676
GO:BP GO:0051716 cellular response to stimulus 0.0137591800114454 7781 30 21 0.7 0.00269888189178769
GO:BP GO:0048519 negative regulation of biological process 0.0139886848824782 5757 16 11 0.6875 0.00191071738752823
GO:BP GO:0031329 regulation of cellular catabolic process 0.0139886848824782 866 13 4 0.307692307692308 0.0046189376443418
GO:BP GO:0001933 negative regulation of protein phosphorylation 0.0140272352917518 373 14 3 0.214285714285714 0.00804289544235925
GO:BP GO:0045444 fat cell differentiation 0.0140729479122371 229 46 4 0.0869565217391304 0.0174672489082969
GO:BP GO:0045619 regulation of lymphocyte differentiation 0.0145293821795541 180 59 4 0.0677966101694915 0.0222222222222222
GO:BP GO:2000134 negative regulation of G1/S transition of mitotic cell cycle 0.0145293821795541 128 40 3 0.075 0.0234375
GO:BP GO:0043523 regulation of neuron apoptotic process 0.0145293821795541 216 24 3 0.125 0.0138888888888889
GO:BP GO:0007165 signal transduction 0.0147370350822374 6309 17 12 0.705882352941177 0.0019020446980504
GO:BP GO:0008152 metabolic process 0.0147704567614499 11827 29 26 0.896551724137931 0.00219835968546546
GO:BP GO:0032259 methylation 0.0150829476244148 372 48 5 0.104166666666667 0.0134408602150538
GO:BP GO:0007162 negative regulation of cell adhesion 0.0152344086175307 304 36 4 0.111111111111111 0.0131578947368421
GO:BP GO:0030968 endoplasmic reticulum unfolded protein response 0.0152963111969802 128 41 3 0.0731707317073171 0.0234375
GO:BP GO:0000079 regulation of cyclin-dependent protein serine/threonine kinase activity 0.015377141177728 99 53 3 0.0566037735849057 0.0303030303030303
GO:BP GO:1902807 negative regulation of cell cycle G1/S phase transition 0.0160635132711367 134 40 3 0.075 0.0223880597014925
GO:BP GO:0045582 positive regulation of T cell differentiation 0.0161908808676513 91 59 3 0.0508474576271186 0.032967032967033
GO:BP GO:0042770 signal transduction in response to DNA damage 0.0162106445397881 135 40 3 0.075 0.0222222222222222
GO:BP GO:0071396 cellular response to lipid 0.0162167429776044 578 10 3 0.3 0.00519031141868512
GO:BP GO:1904029 regulation of cyclin-dependent protein kinase activity 0.0165992412156756 103 53 3 0.0566037735849057 0.029126213592233
GO:BP GO:0002822 regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains 0.0172533692435462 152 37 3 0.0810810810810811 0.0197368421052632
GO:BP GO:0031347 regulation of defense response 0.0172533692435462 704 17 4 0.235294117647059 0.00568181818181818
GO:BP GO:2001234 negative regulation of apoptotic signaling pathway 0.0172533692435462 236 24 3 0.125 0.0127118644067797
GO:BP GO:0071496 cellular response to external stimulus 0.017377253739467 322 36 4 0.111111111111111 0.0124223602484472
GO:BP GO:0042326 negative regulation of phosphorylation 0.0174376810000346 420 14 3 0.214285714285714 0.00714285714285714
GO:BP GO:0070848 response to growth factor 0.0174376810000346 759 16 4 0.25 0.00527009222661397
GO:BP GO:0046631 alpha-beta T cell activation 0.0178358654626714 155 37 3 0.0810810810810811 0.0193548387096774
GO:BP GO:0050793 regulation of developmental process 0.0185107908068754 2605 28 10 0.357142857142857 0.00383877159309021
GO:BP GO:0045787 positive regulation of cell cycle 0.0186167687807034 403 48 5 0.104166666666667 0.0124069478908189
GO:BP GO:0031668 cellular response to extracellular stimulus 0.0186167687807034 248 24 3 0.125 0.0120967741935484
GO:BP GO:0051402 neuron apoptotic process 0.0187821274355324 250 24 3 0.125 0.012
GO:BP GO:0009991 response to extracellular stimulus 0.0188485576784647 512 24 4 0.166666666666667 0.0078125
GO:BP GO:0043086 negative regulation of catalytic activity 0.0188991156045866 851 15 4 0.266666666666667 0.00470035252643948
GO:BP GO:0051338 regulation of transferase activity 0.0193253101227472 1035 20 5 0.25 0.00483091787439614
GO:BP GO:0034620 cellular response to unfolded protein 0.019332165562566 149 41 3 0.0731707317073171 0.0201342281879195
GO:BP GO:0043434 response to peptide hormone 0.019332165562566 462 27 4 0.148148148148148 0.00865800865800866
GO:BP GO:0050794 regulation of cellular process 0.019332165562566 11473 17 16 0.941176470588235 0.00139457857578663
GO:BP GO:0006952 defense response 0.0195975138147874 1818 17 6 0.352941176470588 0.0033003300330033
GO:BP GO:0000077 DNA damage checkpoint 0.0195975138147874 154 40 3 0.075 0.0194805194805195
GO:BP GO:0045621 positive regulation of lymphocyte differentiation 0.0195975138147874 104 59 3 0.0508474576271186 0.0288461538461538
GO:BP GO:0071704 organic substance metabolic process 0.0198489752284986 11326 29 25 0.862068965517241 0.00220731061274943
GO:BP GO:0044238 primary metabolic process 0.0199235324449324 10584 29 24 0.827586206896552 0.00226757369614512
GO:BP GO:0051240 positive regulation of multicellular organismal process 0.0199235324449324 1455 49 10 0.204081632653061 0.00687285223367698
GO:BP GO:0009894 regulation of catabolic process 0.0199235324449324 1033 13 4 0.307692307692308 0.00387221684414327
GO:BP GO:0044703 multi-organism reproductive process 0.0215629744720779 1040 7 3 0.428571428571429 0.00288461538461538
GO:BP GO:0031570 DNA integrity checkpoint 0.021693225719521 164 40 3 0.075 0.0182926829268293
GO:BP GO:0023052 signaling 0.022488964881183 6810 17 12 0.705882352941177 0.00176211453744493
GO:BP GO:0006417 regulation of translation 0.0225355676215163 462 15 3 0.2 0.00649350649350649
GO:BP GO:0007154 cell communication 0.022880156051423 6829 17 12 0.705882352941177 0.00175721189046713
GO:BP GO:0035967 cellular response to topologically incorrect protein 0.0238318081558328 168 41 3 0.0731707317073171 0.0178571428571429
GO:BP GO:0000082 G1/S transition of mitotic cell cycle 0.0238318081558328 283 48 4 0.0833333333333333 0.0141342756183746
GO:BP GO:0006469 negative regulation of protein kinase activity 0.0238318081558328 251 54 4 0.0740740740740741 0.0159362549800797
GO:BP GO:0043065 positive regulation of apoptotic process 0.0238318081558328 604 23 4 0.173913043478261 0.00662251655629139
GO:BP GO:0022408 negative regulation of cell-cell adhesion 0.023947817836344 194 36 3 0.0833333333333333 0.0154639175257732
GO:BP GO:0001568 blood vessel development 0.0240190967771335 792 28 5 0.178571428571429 0.00631313131313131
GO:BP GO:0007610 behavior 0.0243692497869017 586 24 4 0.166666666666667 0.0068259385665529
GO:BP GO:0019220 regulation of phosphate metabolic process 0.0245338588075689 1645 20 6 0.3 0.00364741641337386
GO:BP GO:0051174 regulation of phosphorus metabolic process 0.0245338588075689 1645 20 6 0.3 0.00364741641337386
GO:BP GO:0010628 positive regulation of gene expression 0.0245338588075689 1160 36 7 0.194444444444444 0.00603448275862069
GO:BP GO:0043068 positive regulation of programmed cell death 0.0247738092682291 621 23 4 0.173913043478261 0.00644122383252818
GO:BP GO:0034976 response to endoplasmic reticulum stress 0.0251254626173467 298 47 4 0.0851063829787234 0.0134228187919463
GO:BP GO:1903364 positive regulation of cellular protein catabolic process 0.0252208048745408 154 47 3 0.0638297872340425 0.0194805194805195
GO:BP GO:0009966 regulation of signal transduction 0.0255042889133275 3165 41 14 0.341463414634146 0.00442338072669826
GO:BP GO:0031399 regulation of protein modification process 0.0255042889133275 1671 20 6 0.3 0.00359066427289048
GO:BP GO:0021543 pallium development 0.0255855789047262 171 43 3 0.0697674418604651 0.0175438596491228
GO:BP GO:0072331 signal transduction by p53 class mediator 0.0256717170929538 268 53 4 0.0754716981132075 0.0149253731343284
GO:BP GO:0007166 cell surface receptor signaling pathway 0.0262878343156514 3210 29 11 0.379310344827586 0.00342679127725857
GO:BP GO:0001818 negative regulation of cytokine production 0.0263338750871251 381 20 3 0.15 0.0078740157480315
GO:BP GO:0051239 regulation of multicellular organismal process 0.0263338750871251 2861 28 10 0.357142857142857 0.0034952813701503
GO:BP GO:0051707 response to other organism 0.0263338750871251 1592 10 4 0.4 0.00251256281407035
GO:BP GO:0043207 response to external biotic stimulus 0.0264110024203553 1594 10 4 0.4 0.00250941028858218
GO:BP GO:0001944 vasculature development 0.0264122672924348 830 28 5 0.178571428571429 0.00602409638554217
GO:BP GO:0006986 response to unfolded protein 0.0265961330738685 184 41 3 0.0731707317073171 0.016304347826087
GO:BP GO:0043412 macromolecule modification 0.0277256371760403 4257 20 10 0.5 0.00234907211651398
GO:BP GO:0009607 response to biotic stimulus 0.0277256371760403 1626 10 4 0.4 0.002460024600246
GO:BP GO:0072359 circulatory system development 0.0277256371760403 1194 28 6 0.214285714285714 0.0050251256281407
GO:BP GO:0098609 cell-cell adhesion 0.0279517113046493 894 37 6 0.162162162162162 0.00671140939597315
GO:BP GO:0090068 positive regulation of cell cycle process 0.028014828176835 309 48 4 0.0833333333333333 0.0129449838187702
GO:BP GO:0044843 cell cycle G1/S phase transition 0.028014828176835 309 48 4 0.0833333333333333 0.0129449838187702
GO:BP GO:0034248 regulation of cellular amide metabolic process 0.028014828176835 535 15 3 0.2 0.00560747663551402
GO:BP GO:0048646 anatomical structure formation involved in morphogenesis 0.0280251471013826 1202 28 6 0.214285714285714 0.00499168053244592
GO:BP GO:0033673 negative regulation of kinase activity 0.028175013816163 275 54 4 0.0740740740740741 0.0145454545454545
GO:BP GO:0050678 regulation of epithelial cell proliferation 0.0286253379565031 401 20 3 0.15 0.00748129675810474
GO:BP GO:0001932 regulation of protein phosphorylation 0.0294777919964244 1240 20 5 0.25 0.00403225806451613
GO:BP GO:0050789 regulation of biological process 0.0295807422969343 12091 17 16 0.941176470588235 0.00132329832106526
GO:BP GO:1902531 regulation of intracellular signal transduction 0.0297520754410004 1842 14 5 0.357142857142857 0.00271444082519001
GO:BP GO:0001817 regulation of cytokine production 0.0313743927865295 806 20 4 0.2 0.00496277915632754
GO:BP GO:0045859 regulation of protein kinase activity 0.0313769615932082 809 20 4 0.2 0.00494437577255871
GO:BP GO:0035966 response to topologically incorrect protein 0.0319574715211251 205 41 3 0.0731707317073171 0.0146341463414634
GO:BP GO:0006974 cellular response to DNA damage stimulus 0.0331678283951276 888 51 7 0.137254901960784 0.00788288288288288
GO:BP GO:0045785 positive regulation of cell adhesion 0.0332777676954416 437 37 4 0.108108108108108 0.0091533180778032
GO:BP GO:0010646 regulation of cell communication 0.0333902927505658 3543 54 18 0.333333333333333 0.00508044030482642
GO:BP GO:0001816 cytokine production 0.0345470862730517 844 20 4 0.2 0.004739336492891
GO:BP GO:0048598 embryonic morphogenesis 0.0347919084945823 595 28 4 0.142857142857143 0.00672268907563025
GO:BP GO:0030900 forebrain development 0.0354107592441279 385 43 4 0.0930232558139535 0.0103896103896104
GO:BP GO:0023051 regulation of signaling 0.0356755895936475 3578 54 18 0.333333333333333 0.00503074343208496
GO:BP GO:0050673 epithelial cell proliferation 0.0362431882002367 460 20 3 0.15 0.00652173913043478
GO:BP GO:0022409 positive regulation of cell-cell adhesion 0.0367505773342275 284 59 4 0.0677966101694915 0.0140845070422535
GO:BP GO:0065009 regulation of molecular function 0.0377172707659357 3221 16 7 0.4375 0.00217323812480596
GO:BP GO:0050776 regulation of immune response 0.0384572200589376 996 37 6 0.162162162162162 0.00602409638554217
GO:BP GO:0060322 head development 0.0388197079103289 798 46 6 0.130434782608696 0.0075187969924812
GO:BP GO:0006955 immune response 0.0389386345817743 2311 37 10 0.27027027027027 0.0043271311120727
GO:BP GO:0002252 immune effector process 0.0393313119385378 1309 37 7 0.189189189189189 0.0053475935828877
GO:BP GO:0065008 regulation of biological quality 0.0397273998912124 4131 16 8 0.5 0.00193657709997579
GO:BP GO:0008285 negative regulation of cell population proliferation 0.0397273998912124 790 47 6 0.127659574468085 0.00759493670886076
GO:BP GO:0140014 mitotic nuclear division 0.0399473015774113 302 32 3 0.09375 0.00993377483443709
GO:BP GO:0043549 regulation of kinase activity 0.0414538456874576 921 20 4 0.2 0.00434310532030402
GO:BP GO:0071900 regulation of protein serine/threonine kinase activity 0.0414538456874576 503 54 5 0.0925925925925926 0.0099403578528827
GO:BP GO:0030336 negative regulation of cell migration 0.0414538456874576 353 28 3 0.107142857142857 0.0084985835694051
GO:BP GO:0042110 T cell activation 0.0423061838402943 489 37 4 0.108108108108108 0.0081799591002045
GO:BP GO:0042325 regulation of phosphorylation 0.0427959170304947 1431 20 5 0.25 0.00349406009783368
GO:BP GO:0070727 cellular macromolecule localization 0.0428162068712735 2024 49 11 0.224489795918367 0.00543478260869565
GO:BP GO:0048511 rhythmic process 0.0431338151687632 307 59 4 0.0677966101694915 0.0130293159609121
GO:BP GO:0048870 cell motility 0.0443761877606804 1828 28 7 0.25 0.00382932166301969
GO:BP GO:0051674 localization of cell 0.0443761877606804 1828 28 7 0.25 0.00382932166301969
GO:BP GO:0010629 negative regulation of gene expression 0.0446078030751504 1460 20 5 0.25 0.00342465753424658
GO:BP GO:2000146 negative regulation of cell motility 0.0446078030751504 369 28 3 0.107142857142857 0.00813008130081301
GO:BP GO:0007178 transmembrane receptor protein serine/threonine kinase signaling pathway 0.0446078030751504 369 28 3 0.107142857142857 0.00813008130081301
GO:BP GO:0043409 negative regulation of MAPK cascade 0.0449466078698815 190 54 3 0.0555555555555556 0.0157894736842105
GO:BP GO:0032270 positive regulation of cellular protein metabolic process 0.04606223222311 1477 20 5 0.25 0.003385240352065
GO:BP GO:0051271 negative regulation of cellular component movement 0.0462569570917224 377 28 3 0.107142857142857 0.00795755968169761
GO:BP GO:0036211 protein modification process 0.0466296589531123 4041 20 9 0.45 0.0022271714922049
GO:BP GO:0080135 regulation of cellular response to stress 0.0466296589531123 725 15 3 0.2 0.00413793103448276
GO:BP GO:0006464 cellular protein modification process 0.0466296589531123 4041 20 9 0.45 0.0022271714922049
GO:BP GO:0051249 regulation of lymphocyte activation 0.0474332823377586 518 37 4 0.108108108108108 0.00772200772200772
GO:BP GO:0048584 positive regulation of response to stimulus 0.0495901911326979 2344 28 8 0.285714285714286 0.00341296928327645
GO:BP GO:0065007 biological regulation 0.0496214964814232 12809 17 16 0.941176470588235 0.00124912171129674
GO:CC GO:0035976 transcription factor AP-1 complex 1.65692993273164e-06 4 27 3 0.111111111111111 0.75
GO:CC GO:0005634 nucleus 1.12512955847839e-05 7592 41 33 0.804878048780488 0.00434668071654373
GO:CC GO:0000785 chromatin 5.40203056200536e-05 1526 29 12 0.413793103448276 0.00786369593709043
GO:CC GO:0005694 chromosome 0.000560506545527767 2071 29 12 0.413793103448276 0.00579430226943506
GO:CC GO:0005654 nucleoplasm 0.000560506545527767 4102 40 21 0.525 0.00511945392491468
GO:CC GO:0031981 nuclear lumen 0.000560506545527767 4444 46 24 0.521739130434783 0.0054005400540054
GO:CC GO:0043233 organelle lumen 0.00193524419750452 5565 46 26 0.565217391304348 0.00467205750224618
GO:CC GO:0031974 membrane-enclosed lumen 0.00193524419750452 5565 46 26 0.565217391304348 0.00467205750224618
GO:CC GO:0043232 intracellular non-membrane-bounded organelle 0.0021270140616175 5338 29 18 0.620689655172414 0.00337204945672537
GO:CC GO:0043228 non-membrane-bounded organelle 0.0021270140616175 5346 29 18 0.620689655172414 0.00336700336700337
GO:CC GO:0070013 intracellular organelle lumen 0.00270658416319198 5402 46 25 0.543478260869565 0.0046279155868197
GO:CC GO:0043231 intracellular membrane-bounded organelle 0.00422811925739387 11296 48 40 0.833333333333333 0.00354107648725212
GO:CC GO:0043229 intracellular organelle 0.00738339788803874 12491 29 27 0.931034482758621 0.0021615563205508
GO:CC GO:0043227 membrane-bounded organelle 0.0145278839669277 12858 48 42 0.875 0.00326644890340644
GO:CC GO:0005622 intracellular anatomical structure 0.0164024738941739 14790 43 41 0.953488372093023 0.00277214334009466
GO:CC GO:0043226 organelle 0.0385354598376314 14008 43 39 0.906976744186046 0.0027841233580811
GO:MF GO:0001216 DNA-binding transcription activator activity 1.2700505871375e-06 455 36 10 0.277777777777778 0.021978021978022
GO:MF GO:0001228 DNA-binding transcription activator activity, RNA polymerase II-specific 1.2700505871375e-06 451 36 10 0.277777777777778 0.0221729490022173
GO:MF GO:0140110 transcription regulator activity 0.000184076997911931 1935 29 13 0.448275862068966 0.00671834625322997
GO:MF GO:0000987 cis-regulatory region sequence-specific DNA binding 0.000200732827495721 1209 27 10 0.37037037037037 0.00827129859387924
GO:MF GO:0000978 RNA polymerase II cis-regulatory region sequence-specific DNA binding 0.000200732827495721 1190 27 10 0.37037037037037 0.00840336134453781
GO:MF GO:0003677 DNA binding 0.000216617611626407 2486 29 14 0.482758620689655 0.00563153660498793
GO:MF GO:0003700 DNA-binding transcription factor activity 0.000216617611626407 1441 29 11 0.379310344827586 0.00763358778625954
GO:MF GO:0000977 RNA polymerase II transcription regulatory region sequence-specific DNA binding 0.00048632693337639 1408 27 10 0.37037037037037 0.00710227272727273
GO:MF GO:0000976 transcription regulatory region sequence-specific DNA binding 0.000594301913400699 1507 27 10 0.37037037037037 0.006635700066357
GO:MF GO:0000981 DNA-binding transcription factor activity, RNA polymerase II-specific 0.000594301913400699 1375 29 10 0.344827586206897 0.00727272727272727
GO:MF GO:0001067 regulatory region nucleic acid binding 0.000594301913400699 1509 27 10 0.37037037037037 0.00662690523525514
GO:MF GO:0043565 sequence-specific DNA binding 0.000594301913400699 1673 29 11 0.379310344827586 0.00657501494321578
GO:MF GO:1990837 sequence-specific double-stranded DNA binding 0.000773471337989254 1570 27 10 0.37037037037037 0.00636942675159236
GO:MF GO:0008134 transcription factor binding 0.000906405595407421 676 28 7 0.25 0.0103550295857988
GO:MF GO:0061629 RNA polymerase II-specific DNA-binding transcription factor binding 0.000969186991887399 281 28 5 0.178571428571429 0.0177935943060498
GO:MF GO:0003690 double-stranded DNA binding 0.00103589902161547 1664 27 10 0.37037037037037 0.00600961538461538
GO:MF GO:0046332 SMAD binding 0.00330691628479854 78 28 3 0.107142857142857 0.0384615384615385
GO:MF GO:0001102 RNA polymerase II activating transcription factor binding 0.00337283554007416 49 46 3 0.0652173913043478 0.0612244897959184
GO:MF GO:0140297 DNA-binding transcription factor binding 0.00337283554007416 391 28 5 0.178571428571429 0.0127877237851662
GO:MF GO:0019900 kinase binding 0.00955936170403823 752 20 5 0.25 0.00664893617021277
GO:MF GO:0033613 activating transcription factor binding 0.0101904144184125 83 46 3 0.0652173913043478 0.036144578313253
GO:MF GO:0005515 protein binding 0.0155682013629965 14767 54 51 0.944444444444444 0.00345364664454527
GO:MF GO:0003676 nucleic acid binding 0.018847718997641 4276 29 14 0.482758620689655 0.00327408793264733
GO:MF GO:0019899 enzyme binding 0.018847718997641 2074 28 9 0.321428571428571 0.00433944069431051
GO:MF GO:0003682 chromatin binding 0.0268191922904509 571 50 6 0.12 0.010507880910683
GO:MF GO:0019901 protein kinase binding 0.030095855975298 673 20 4 0.2 0.00594353640416048
GO:MF GO:0008757 S-adenosylmethionine-dependent methyltransferase activity 0.0407845779315002 161 48 3 0.0625 0.0186335403726708
GO:MF GO:0046982 protein heterodimerization activity 0.0417244482171936 357 43 4 0.0930232558139535 0.0112044817927171
KEGG KEGG:04380 Osteoclast differentiation 0.000224415993281117 125 9 4 0.444444444444444 0.032
KEGG KEGG:04668 TNF signaling pathway 0.000224415993281117 112 10 4 0.4 0.0357142857142857
KEGG KEGG:04657 IL-17 signaling pathway 0.000224415993281117 92 10 4 0.4 0.0434782608695652
KEGG KEGG:04928 Parathyroid hormone synthesis, secretion and action 0.00759416629729238 106 27 4 0.148148148148148 0.0377358490566038
KEGG KEGG:05162 Measles 0.00855725765664982 139 10 3 0.3 0.0215827338129496
KEGG KEGG:05166 Human T-cell leukemia virus 1 infection 0.00855725765664982 216 16 4 0.25 0.0185185185185185
KEGG KEGG:04625 C-type lectin receptor signaling pathway 0.00980202258368276 104 59 5 0.0847457627118644 0.0480769230769231
KEGG KEGG:05167 Kaposi sarcoma-associated herpesvirus infection 0.00980202258368276 193 9 3 0.333333333333333 0.0155440414507772
KEGG KEGG:04210 Apoptosis 0.0103630720264608 136 13 3 0.230769230769231 0.0220588235294118
KEGG KEGG:04064 NF-kappa B signaling pathway 0.0250487895371886 102 57 4 0.0701754385964912 0.0392156862745098
MIRNA MIRNA:hsa-miR-29a-3p hsa-miR-29a-3p 0.00077888333815218 264 42 8 0.19047619047619 0.0303030303030303
MIRNA MIRNA:hsa-miR-29c-3p hsa-miR-29c-3p 0.00412547909188284 253 45 7 0.155555555555556 0.0276679841897233
MIRNA MIRNA:hsa-miR-29b-3p hsa-miR-29b-3p 0.00412547909188284 260 42 7 0.166666666666667 0.0269230769230769
MIRNA MIRNA:hsa-miR-101-3p hsa-miR-101-3p 0.00412547909188284 391 13 5 0.384615384615385 0.0127877237851662
MIRNA MIRNA:hsa-miR-5700 hsa-miR-5700 0.00819118356299179 89 11 3 0.272727272727273 0.0337078651685393
MIRNA MIRNA:hsa-miR-663a hsa-miR-663a 0.0128122031807365 143 27 4 0.148148148148148 0.027972027972028
MIRNA MIRNA:hsa-miR-6077 hsa-miR-6077 0.0128122031807365 278 6 3 0.5 0.0107913669064748
MIRNA MIRNA:hsa-miR-139-5p hsa-miR-139-5p 0.0128122031807365 104 13 3 0.230769230769231 0.0288461538461538
MIRNA MIRNA:hsa-miR-3663-3p hsa-miR-3663-3p 0.0163510438191142 56 31 3 0.0967741935483871 0.0535714285714286
MIRNA MIRNA:hsa-miR-588 hsa-miR-588 0.0166276575373955 225 58 6 0.103448275862069 0.0266666666666667
MIRNA MIRNA:hsa-miR-3187-3p hsa-miR-3187-3p 0.0186643097915815 233 58 6 0.103448275862069 0.0257510729613734
MIRNA MIRNA:hsa-miR-4435 hsa-miR-4435 0.0201267670421977 246 58 6 0.103448275862069 0.024390243902439
MIRNA MIRNA:hsa-miR-4701-5p hsa-miR-4701-5p 0.0201267670421977 245 58 6 0.103448275862069 0.0244897959183673
MIRNA MIRNA:hsa-miR-4749-3p hsa-miR-4749-3p 0.0201267670421977 67 31 3 0.0967741935483871 0.0447761194029851
MIRNA MIRNA:hsa-miR-3178 hsa-miR-3178 0.0248815547288529 73 33 3 0.0909090909090909 0.0410958904109589
MIRNA MIRNA:hsa-miR-539-5p hsa-miR-539-5p 0.0248815547288529 210 48 5 0.104166666666667 0.0238095238095238
MIRNA MIRNA:hsa-miR-885-3p hsa-miR-885-3p 0.0284604589457868 77 34 3 0.0882352941176471 0.038961038961039
MIRNA MIRNA:hsa-miR-4659b-3p hsa-miR-4659b-3p 0.0304837135727768 228 50 5 0.1 0.0219298245614035
MIRNA MIRNA:hsa-miR-4729 hsa-miR-4729 0.0304837135727768 137 21 3 0.142857142857143 0.0218978102189781
MIRNA MIRNA:hsa-miR-5582-3p hsa-miR-5582-3p 0.0304837135727768 247 45 5 0.111111111111111 0.0202429149797571
MIRNA MIRNA:hsa-miR-193a-3p hsa-miR-193a-3p 0.0304837135727768 128 50 4 0.08 0.03125
MIRNA MIRNA:hsa-miR-4267 hsa-miR-4267 0.0304837135727768 156 42 4 0.0952380952380952 0.0256410256410256
MIRNA MIRNA:hsa-miR-4659a-3p hsa-miR-4659a-3p 0.0304837135727768 228 50 5 0.1 0.0219298245614035
MIRNA MIRNA:hsa-miR-335-5p hsa-miR-335-5p 0.0304837135727768 2571 45 17 0.377777777777778 0.00661221314663555
MIRNA MIRNA:hsa-miR-1207-5p hsa-miR-1207-5p 0.0347089615548488 287 13 3 0.230769230769231 0.0104529616724739
MIRNA MIRNA:hsa-miR-125a-5p hsa-miR-125a-5p 0.0347089615548488 269 13 3 0.230769230769231 0.0111524163568773
MIRNA MIRNA:hsa-miR-4454 hsa-miR-4454 0.0347089615548488 58 58 3 0.0517241379310345 0.0517241379310345
MIRNA MIRNA:hsa-miR-17-5p hsa-miR-17-5p 0.0347089615548488 1174 58 12 0.206896551724138 0.010221465076661
MIRNA MIRNA:hsa-miR-4763-3p hsa-miR-4763-3p 0.0347089615548488 282 13 3 0.230769230769231 0.0106382978723404
MIRNA MIRNA:hsa-miR-4796-3p hsa-miR-4796-3p 0.0347089615548488 285 12 3 0.25 0.0105263157894737
MIRNA MIRNA:hsa-miR-505-5p hsa-miR-505-5p 0.0347089615548488 133 26 3 0.115384615384615 0.0225563909774436
MIRNA MIRNA:hsa-miR-548ae-3p hsa-miR-548ae-3p 0.0347089615548488 291 45 5 0.111111111111111 0.0171821305841924
MIRNA MIRNA:hsa-miR-548ah-3p hsa-miR-548ah-3p 0.0347089615548488 289 45 5 0.111111111111111 0.0173010380622837
MIRNA MIRNA:hsa-miR-548x-3p hsa-miR-548x-3p 0.0347089615548488 291 45 5 0.111111111111111 0.0171821305841924
MIRNA MIRNA:hsa-miR-548s hsa-miR-548s 0.0347089615548488 426 58 7 0.120689655172414 0.0164319248826291
MIRNA MIRNA:hsa-miR-548aj-3p hsa-miR-548aj-3p 0.0347089615548488 291 45 5 0.111111111111111 0.0171821305841924
MIRNA MIRNA:hsa-miR-548am-3p hsa-miR-548am-3p 0.0347089615548488 289 45 5 0.111111111111111 0.0173010380622837
MIRNA MIRNA:hsa-miR-548aq-3p hsa-miR-548aq-3p 0.0347089615548488 291 45 5 0.111111111111111 0.0171821305841924
MIRNA MIRNA:hsa-miR-548j-3p hsa-miR-548j-3p 0.0347089615548488 290 45 5 0.111111111111111 0.0172413793103448
MIRNA MIRNA:hsa-miR-181a-5p hsa-miR-181a-5p 0.0405771732175048 543 16 4 0.25 0.00736648250460405
MIRNA MIRNA:hsa-miR-20a-5p hsa-miR-20a-5p 0.0420593801209575 1064 58 11 0.189655172413793 0.0103383458646617
MIRNA MIRNA:hsa-miR-6804-5p hsa-miR-6804-5p 0.0426989858572975 126 33 3 0.0909090909090909 0.0238095238095238
MIRNA MIRNA:hsa-miR-6836-3p hsa-miR-6836-3p 0.0426989858572975 206 42 4 0.0952380952380952 0.0194174757281553
MIRNA MIRNA:hsa-miR-15a-5p hsa-miR-15a-5p 0.0426989858572975 717 13 4 0.307692307692308 0.00557880055788006
REAC REAC:R-HSA-9031628 NGF-stimulated transcription 1.53759129741672e-07 39 59 7 0.11864406779661 0.179487179487179
REAC REAC:R-HSA-198725 Nuclear Events (kinase and transcription factor activation) 1.53759129741672e-07 61 59 8 0.135593220338983 0.131147540983607
REAC REAC:R-HSA-187037 Signaling by NTRK1 (TRKA) 1.14636225217164e-05 112 59 8 0.135593220338983 0.0714285714285714
REAC REAC:R-HSA-166520 Signaling by NTRKs 2.71677995869112e-05 130 59 8 0.135593220338983 0.0615384615384615
REAC REAC:R-HSA-6804115 TP53 regulates transcription of additional cell cycle genes whose exact role in the p53 pathway remain uncertain 0.00247734834714845 21 40 3 0.075 0.142857142857143
REAC REAC:R-HSA-6785807 Interleukin-4 and Interleukin-13 signaling 0.00942147054933484 110 13 3 0.230769230769231 0.0272727272727273
REAC REAC:R-HSA-1280215 Cytokine Signaling in Immune system 0.0122485777598353 842 3 3 1 0.00356294536817102
REAC REAC:R-HSA-6791312 TP53 Regulates Transcription of Cell Cycle Genes 0.0177130231029075 49 40 3 0.075 0.0612244897959184
REAC REAC:R-HSA-449147 Signaling by Interleukins 0.0189607418721031 446 13 4 0.307692307692308 0.00896860986547085
REAC REAC:R-HSA-9006934 Signaling by Receptor Tyrosine Kinases 0.0189607418721031 485 7 3 0.428571428571429 0.00618556701030928
REAC REAC:R-HSA-168256 Immune System 0.0349988241124253 2139 3 3 1 0.00140252454417952
REAC REAC:R-HSA-212436 Generic Transcription Pathway 0.0404954292525836 1180 5 3 0.6 0.00254237288135593
REAC REAC:R-HSA-2262752 Cellular responses to stress 0.0436812576778532 546 28 5 0.178571428571429 0.00915750915750916
REAC REAC:R-HSA-8953897 Cellular responses to external stimuli 0.0459981853383461 560 28 5 0.178571428571429 0.00892857142857143
REAC REAC:R-HSA-73857 RNA Polymerase II Transcription 0.0466186303421453 1301 5 3 0.6 0.00230591852421214
TF TF:M09592 Factor: ATF-1; motif: NRTGACGTMAN 6.56986044706324e-05 4411 59 33 0.559322033898305 0.00748129675810474
TF TF:M09887_1 Factor: CREB1; motif: NRRTGACGTMA; match class: 1 6.56986044706324e-05 1616 59 20 0.338983050847458 0.0123762376237624
TF TF:M09866 Factor: ATF-1; motif: NNRTGACGYMA 0.000625097154374778 3162 59 26 0.440677966101695 0.00822264389626818
TF TF:M00178_1 Factor: CREB; motif: NSTGACGTMANN; match class: 1 0.000625097154374778 1522 33 13 0.393939393939394 0.00854139290407359
TF TF:M00017_1 Factor: ATF; motif: CNSTGACGTNNNYC; match class: 1 0.000637081023966325 2222 33 15 0.454545454545455 0.00675067506750675
TF TF:M00916_1 Factor: CREB; motif: NNTKACGTCANNNS; match class: 1 0.000637081023966325 1692 52 17 0.326923076923077 0.0100472813238771
TF TF:M00810_1 Factor: SRF; motif: SCCAWATAWGGMNMNNNN; match class: 1 0.000637081023966325 7 59 3 0.0508474576271186 0.428571428571429
TF TF:M00917_1 Factor: CREB; motif: CNNTGACGTMA; match class: 1 0.000637081023966325 1590 33 13 0.393939393939394 0.00817610062893082
TF TF:M00177_1 Factor: CREB; motif: NSTGACGTAANN; match class: 1 0.000821822640400262 1363 52 15 0.288461538461538 0.0110051357300073
TF TF:M09600_1 Factor: CREB1; motif: TKACGTCAYNN; match class: 1 0.000821822640400262 1552 52 16 0.307692307692308 0.0103092783505155
TF TF:M11217 Factor: CREB1; motif: NRTGACGYN 0.0011013834335941 2783 59 23 0.389830508474576 0.00826446280991736
TF TF:M09600 Factor: CREB1; motif: TKACGTCAYNN 0.00110437254831535 5324 59 33 0.559322033898305 0.00619834710743802
TF TF:M09868_1 Factor: ATF-3; motif: GGTSACGTGAN; match class: 1 0.00110437254831535 2116 21 11 0.523809523809524 0.00519848771266541
TF TF:M00179_1 Factor: ATF2; motif: VGTGACGTMACN; match class: 1 0.00110437254831535 1778 33 13 0.393939393939394 0.00731158605174353
TF TF:M00178 Factor: CREB; motif: NSTGACGTMANN 0.00148677573207478 5255 53 30 0.566037735849057 0.00570884871550904
TF TF:M00981_1 Factor: CREB,; motif: NTGACGTNA; match class: 1 0.00149404951133482 2904 59 23 0.389830508474576 0.00792011019283747
TF TF:M11309_1 Factor: ATF-2; motif: NRTGACGTMANN; match class: 1 0.00149404951133482 2293 40 16 0.4 0.00697775839511557
TF TF:M01861_1 Factor: ATF-1; motif: TNACGTCAN; match class: 1 0.00158482796891121 1896 33 13 0.393939393939394 0.00685654008438819
TF TF:M00152_1 Factor: SRF; motif: ATGCCCATATATGGWNNT; match class: 1 0.00158482796891121 12 59 3 0.0508474576271186 0.25
TF TF:M10076_1 Factor: SRF; motif: TTNCCWTWTWTGGNCWNN; match class: 1 0.00158482796891121 12 59 3 0.0508474576271186 0.25
TF TF:M11335_1 Factor: ATF-4; motif: GGATGACGTCATCC; match class: 1 0.0017107342799323 2207 47 17 0.361702127659574 0.00770276393294064
TF TF:M00113 Factor: CREB; motif: NNGNTGACGTNN 0.0017107342799323 4801 53 28 0.528301886792453 0.00583211830868569
TF TF:M00053 Factor: c-Rel; motif: SGGRNTTTCC 0.0017107342799323 3672 37 19 0.513513513513513 0.00517429193899782
TF TF:M00186_1 Factor: SRF; motif: GNCCAWATAWGGMN; match class: 1 0.0017107342799323 13 59 3 0.0508474576271186 0.230769230769231
TF TF:M11285_1 Factor: Fra-1; motif: GRTGACGTCATC; match class: 1 0.0017107342799323 4589 52 27 0.519230769230769 0.00588363477881892
TF TF:M00338_1 Factor: ATF; motif: NTGACGTCANYS; match class: 1 0.00210685354101461 1122 33 10 0.303030303030303 0.0089126559714795
TF TF:M11335 Factor: ATF-4; motif: GGATGACGTCATCC 0.00228693284829387 2292 47 17 0.361702127659574 0.00741710296684119
TF TF:M07034_1 Factor: ATF-1; motif: NNNTGACGTNNN; match class: 1 0.0028192627113039 1179 33 10 0.303030303030303 0.00848176420695505
TF TF:M02281 Factor: SP1; motif: CCCCKCCCCC 0.0028192627113039 6480 13 12 0.923076923076923 0.00185185185185185
TF TF:M00916 Factor: CREB; motif: NNTKACGTCANNNS 0.0028192627113039 5889 53 31 0.584905660377358 0.00526405162166752
TF TF:M00039_1 Factor: CREB; motif: TGACGTMA; match class: 1 0.00318808970262736 1482 33 11 0.333333333333333 0.00742240215924426
TF TF:M01820 Factor: CREM; motif: TGACGTCASYN 0.00340106149824745 6303 53 32 0.60377358490566 0.00507694748532445
TF TF:M10076 Factor: SRF; motif: TTNCCWTWTWTGGNCWNN 0.00341390330242502 187 59 6 0.101694915254237 0.0320855614973262
TF TF:M04025_1 Factor: SRF; motif: TGMCCATATATGGKCA; match class: 1 0.00341390330242502 18 59 3 0.0508474576271186 0.166666666666667
TF TF:M09834_1 Factor: ZNF148; motif: NNNNNNCCNNCCCCTCCCCCACCCN; match class: 1 0.00387483491128531 2869 37 16 0.432432432432432 0.00557685604740328
TF TF:M10112_1 Factor: Miz-1; motif: NNRGGWGGGGGAGGGGMRR; match class: 1 0.00389544553092087 4075 9 8 0.888888888888889 0.00196319018404908
TF TF:M00922_1 Factor: SRF; motif: CCAWATAWGGMNMNG; match class: 1 0.00421563733186478 20 59 3 0.0508474576271186 0.15
TF TF:M07312 Factor: ATF-2; motif: NNTGACGTCAN 0.00421563733186478 3483 59 24 0.406779661016949 0.00689061154177433
TF TF:M01820_1 Factor: CREM; motif: TGACGTCASYN; match class: 1 0.00421563733186478 1879 33 12 0.363636363636364 0.00638637573177222
TF TF:M09834 Factor: ZNF148; motif: NNNNNNCCNNCCCCTCCCCCACCCN 0.00464173165652721 6953 13 12 0.923076923076923 0.00172587372357256
TF TF:M07397 Factor: ZBP89; motif: CCCCKCCCCCNN 0.00603028410774892 7143 13 12 0.923076923076923 0.00167996640067199
TF TF:M00017 Factor: ATF; motif: CNSTGACGTNNNYC 0.00603028410774892 7226 53 34 0.641509433962264 0.00470523110988099
TF TF:M10529 Factor: Sp1; motif: RGGGMGGRGSNGGGG 0.00709161384456497 6891 37 25 0.675675675675676 0.00362792047598317
TF TF:M11217_1 Factor: CREB1; motif: NRTGACGYN; match class: 1 0.00762503730838687 457 19 5 0.263157894736842 0.0109409190371991
TF TF:M07221_1 Factor: NF-kappaB1; motif: KGGRNTTTCCM; match class: 1 0.0081794893295887 163 10 3 0.3 0.0184049079754601
TF TF:M07034 Factor: ATF-1; motif: NNNTGACGTNNN 0.00830027811609975 4248 52 24 0.461538461538462 0.00564971751412429
TF TF:M09592_1 Factor: ATF-1; motif: NRTGACGTMAN; match class: 1 0.00830027811609975 1255 59 13 0.220338983050847 0.0103585657370518
TF TF:M07294 Factor: KLF8; motif: HMNDGGGTGT 0.00837384622571671 1361 8 5 0.625 0.00367376928728876
TF TF:M09668 Factor: RelA-p65; motif: GGGRNTTTCCM 0.00837384622571671 3576 13 9 0.692307692307692 0.00251677852348993
TF TF:M07248 Factor: CREB1; motif: NNNNTGACGTNANNN 0.00837384622571671 4266 52 24 0.461538461538462 0.00562587904360056
TF TF:M04025 Factor: SRF; motif: TGMCCATATATGGKCA 0.00877281684264365 28 59 3 0.0508474576271186 0.107142857142857
TF TF:M00179 Factor: ATF2; motif: VGTGACGTMACN 0.0090155182762314 6065 53 30 0.566037735849057 0.00494641384995878
TF TF:M00113_1 Factor: CREB; motif: NNGNTGACGTNN; match class: 1 0.0097433430848565 869 53 10 0.188679245283019 0.0115074798619102
TF TF:M09866_1 Factor: ATF-1; motif: NNRTGACGYMA; match class: 1 0.0110923989791068 955 59 11 0.186440677966102 0.0115183246073298
TF TF:M05439 Factor: RREB-1; motif: GGGWCSA 0.0110923989791068 8635 34 26 0.764705882352941 0.00301100173711639
TF TF:M11302 Factor: batf3; motif: GATGAYGTCATN 0.0110923989791068 308 31 5 0.161290322580645 0.0162337662337662
TF TF:M07040 Factor: GKLF; motif: NNRRGRRNGNSNNN 0.0112497190642908 12705 42 38 0.904761904761905 0.0029909484454939
TF TF:M09887 Factor: CREB1; motif: NRRTGACGTMA 0.0112497190642908 5419 59 30 0.508474576271186 0.00553607676693117
TF TF:M03544 Factor: CREB1; motif: NNNNACGTCANN 0.0112497190642908 4101 52 23 0.442307692307692 0.00560838819800049
TF TF:M04109 Factor: RUNX3; motif: NRACCGCAAACCGCAN 0.0112497190642908 9770 39 31 0.794871794871795 0.00317297850562948
TF TF:M11291_1 Factor: ATF-3; motif: NRTGACGTCAYN; match class: 1 0.0112737683298334 4408 52 24 0.461538461538462 0.00544464609800363
TF TF:M03557_1 Factor: P50; motif: GGRRANTCCCNN; match class: 1 0.0112737683298334 1292 38 10 0.263157894736842 0.00773993808049536
TF TF:M00803_1 Factor: E2F; motif: GGCGSG; match class: 1 0.0117375694066477 10230 18 17 0.944444444444444 0.00166177908113392
TF TF:M00981 Factor: CREB,; motif: NTGACGTNA 0.0121428487882109 8345 25 20 0.8 0.00239664469742361
TF TF:M11337_1 Factor: ATF-4; motif: GGATGACGTCATCC; match class: 1 0.0128918305720664 2806 47 17 0.361702127659574 0.00605844618674269
TF TF:M01219 Factor: SP1:SP3; motif: CCSCCCCCYCC 0.0129202483543459 6812 41 26 0.634146341463415 0.00381679389312977
TF TF:M07226_1 Factor: SP1; motif: NCCCCKCCCCC; match class: 1 0.0131887779396455 3915 13 9 0.692307692307692 0.00229885057471264
TF TF:M12057 Factor: ZBP99; motif: GCCCMTCCCCCR 0.0132295082213994 5225 19 13 0.684210526315789 0.00248803827751196
TF TF:M01861 Factor: ATF-1; motif: TNACGTCAN 0.0144549397799689 6294 53 30 0.566037735849057 0.00476644423260248
TF TF:M08930_1 Factor: JUND:FRA-1; motif: RTGACGTMAY; match class: 1 0.0165140784437009 1607 33 10 0.303030303030303 0.00622277535780958
TF TF:M00152 Factor: SRF; motif: ATGCCCATATATGGWNNT 0.016991861579846 182 59 5 0.0847457627118644 0.0274725274725275
TF TF:M03882 Factor: RelB:p50; motif: RGAAANTCCCYNNHGC 0.0171139557704938 4474 59 26 0.440677966101695 0.00581135449262405
TF TF:M04196_1 Factor: USF1; motif: RNCACGTGAY; match class: 1 0.0175842936033882 856 49 9 0.183673469387755 0.0105140186915888
TF TF:M08993_1 Factor: ZNF777; motif: GTCCGYCCCGTCSAACAAT; match class: 1 0.0175842936033882 4112 29 15 0.517241379310345 0.00364785992217899
TF TF:M12057_1 Factor: ZBP99; motif: GCCCMTCCCCCR; match class: 1 0.0175842936033882 1359 39 10 0.256410256410256 0.00735835172921266
TF TF:M11337 Factor: ATF-4; motif: GGATGACGTCATCC 0.0175842936033882 2911 47 17 0.361702127659574 0.00583991755410512
TF TF:M07226 Factor: SP1; motif: NCCCCKCCCCC 0.0178980626903063 8292 13 12 0.923076923076923 0.00144717800289436
TF TF:M09826_1 Factor: BTEB3; motif: CCNNSCCNSCCCCKCCCCC; match class: 1 0.0191170661559629 7508 37 25 0.675675675675676 0.00332978156632925
TF TF:M10112 Factor: Miz-1; motif: NNRGGWGGGGGAGGGGMRR 0.0191444054333314 8711 40 29 0.725 0.00332912409597061
TF TF:M00917 Factor: CREB; motif: CNNTGACGTMA 0.0193268808151485 5578 52 27 0.519230769230769 0.00484044460380065
TF TF:M07350 Factor: BMAL1; motif: AGCCAYKKGA 0.0195944703871913 1392 46 11 0.239130434782609 0.00790229885057471
TF TF:M00800 Factor: AP-2; motif: GSCCSCRGGCNRNRNN 0.0196103465485366 9119 29 23 0.793103448275862 0.00252220638227876
TF TF:M04953_1 Factor: Sp1; motif: GGNDGGRGGCGGGG; match class: 1 0.0200840716828127 4065 11 8 0.727272727272727 0.0019680196801968
TF TF:M07312_1 Factor: ATF-2; motif: NNTGACGTCAN; match class: 1 0.0202628514025826 1070 33 8 0.242424242424242 0.00747663551401869
TF TF:M07618 Factor: SRF; motif: CCTTWTATGGNN 0.0204407308390507 167 16 3 0.1875 0.0179640718562874
TF TF:M00691_1 Factor: ATF-1; motif: CYYTGACGTCA; match class: 1 0.0206225078155315 854 15 5 0.333333333333333 0.00585480093676815
TF TF:M00810 Factor: SRF; motif: SCCAWATAWGGMNMNNNN 0.0206334956888082 109 59 4 0.0677966101694915 0.036697247706422
TF TF:M11220_1 Factor: CREB1; motif: NNTGACGTCANN; match class: 1 0.0219348914857627 1713 33 10 0.303030303030303 0.00583771161704612
TF TF:M07313 Factor: ATF-3; motif: SNTGACGYNATN 0.0220877422199922 2894 53 18 0.339622641509434 0.00621976503109883
TF TF:M01862 Factor: ATF-2; motif: NNNTGACGTNAN 0.0220877422199922 3230 52 19 0.365384615384615 0.00588235294117647
TF TF:M11220 Factor: CREB1; motif: NNTGACGTCANN 0.0222862266822269 1725 33 10 0.303030303030303 0.00579710144927536
TF TF:M00665_1 Factor: Sp3; motif: ASMCTTGGGSRGGG; match class: 1 0.0222862266822269 2293 7 5 0.714285714285714 0.00218054949847362
TF TF:M11303_1 Factor: batf3; motif: GRTGACGTCATC; match class: 1 0.022372719008437 584 33 6 0.181818181818182 0.0102739726027397
TF TF:M11291 Factor: ATF-3; motif: NRTGACGTCAYN 0.0224436667421112 4720 52 24 0.461538461538462 0.00508474576271186
TF TF:M00215_1 Factor: SRF; motif: DCCWTATATGGNCWN; match class: 1 0.0245361744743817 49 59 3 0.0508474576271186 0.0612244897959184
TF TF:M02279_1 Factor: CREB1; motif: TGACGTCA; match class: 1 0.024812927696793 851 33 7 0.212121212121212 0.0082256169212691
TF TF:M01660 Factor: GABP-alpha; motif: CTTCCK 0.0249914525143688 11116 59 46 0.779661016949153 0.00413817920115149
TF TF:M02023 Factor: MAZ; motif: NKGGGAGGGGRGGR 0.0266637337651965 7134 13 11 0.846153846153846 0.00154191197084385
TF TF:M11303 Factor: batf3; motif: GRTGACGTCATC 0.0266637337651965 614 33 6 0.181818181818182 0.00977198697068404
TF TF:M00691 Factor: ATF-1; motif: CYYTGACGTCA 0.0266637337651965 4489 52 23 0.442307692307692 0.00512363555357541
TF TF:M11621 Factor: Sox-14; motif: NCGAACAATG 0.0297946179628367 245 54 5 0.0925925925925926 0.0204081632653061
TF TF:M00208 Factor: NF-kappaB; motif: NGGGACTTTCCA 0.0300987106839745 3757 47 19 0.404255319148936 0.00505722651051371
TF TF:M07246 Factor: ATF-4; motif: NNTKRCRTCANS 0.0300987106839745 2835 47 16 0.340425531914894 0.00564373897707231
TF TF:M09826 Factor: BTEB3; motif: CCNNSCCNSCCCCKCCCCC 0.0300987106839745 11467 38 32 0.842105263157895 0.00279061655184442
TF TF:M01199_1 Factor: RNF96; motif: BCCCGCRGCC; match class: 1 0.0308774962796706 4322 48 21 0.4375 0.0048588616381305
TF TF:M11223 Factor: CREB1; motif: NRTGACGTCANN 0.0308774962796706 2810 52 17 0.326923076923077 0.00604982206405694
TF TF:M11257_1 Factor: AIBZIP; motif: NRTGACGTCAYN; match class: 1 0.0308967816107152 899 33 7 0.212121212121212 0.00778642936596218
TF TF:M00933_1 Factor: Sp1; motif: CCCCGCCCCN; match class: 1 0.0308967816107152 5166 36 19 0.527777777777778 0.00367789392179636
TF TF:M07250_1 Factor: E2F-1; motif: NNNSSCGCSAANN; match class: 1 0.0312215594158127 5515 52 26 0.5 0.00471441523118767
TF TF:M07397_1 Factor: ZBP89; motif: CCCCKCCCCCNN; match class: 1 0.0312930148680163 2951 9 6 0.666666666666667 0.00203320908166723
TF TF:M03544_1 Factor: CREB1; motif: NNNNACGTCANN; match class: 1 0.0316089733626478 1196 33 8 0.242424242424242 0.00668896321070234
TF TF:M09969 Factor: EKLF; motif: NGGGYGKGGCNNGG 0.0317369343143283 4589 37 18 0.486486486486487 0.00392242318587928
TF TF:M00177 Factor: CREB; motif: NSTGACGTAANN 0.0325274753144791 5221 52 25 0.480769230769231 0.00478835472131776
TF TF:M01304 Factor: SRF; motif: NNCCAWAWAAGGV 0.0325274753144791 218 16 3 0.1875 0.0137614678899083
TF TF:M01843 Factor: DEC2; motif: SNTCACGTGS 0.0325274753144791 3788 10 7 0.7 0.00184794086589229
TF TF:M01778 Factor: PLAG1; motif: GRGGCNNHNNNRRGGG 0.0332470243352738 2743 36 13 0.361111111111111 0.004739336492891
TF TF:M07040_1 Factor: GKLF; motif: NNRRGRRNGNSNNN; match class: 1 0.0332470243352738 8156 29 21 0.724137931034483 0.0025747915644924
TF TF:M01864 Factor: ATF-4; motif: KACGTCAKS 0.0332470243352738 4477 16 10 0.625 0.00223363859727496
TF TF:M00915_1 Factor: AP-2; motif: SNNNCCNCAGGCN; match class: 1 0.0332470243352738 4551 29 15 0.517241379310345 0.003295978905735
TF TF:M07248_1 Factor: CREB1; motif: NNNNTGACGTNANNN; match class: 1 0.0332470243352738 1216 33 8 0.242424242424242 0.00657894736842105
TF TF:M11273_1 Factor: JunB; motif: GATGACGTCAYC; match class: 1 0.0332470243352738 6582 52 29 0.557692307692308 0.00440595563658462
TF TF:M00041_1 Factor: ATF2:c-Jun; motif: TGACGTYA; match class: 1 0.0332470243352738 1219 33 8 0.242424242424242 0.00656275635767022
TF TF:M00114 Factor: Tax/CREB; motif: GGGGGTTGACGYANA 0.0332505863231067 6548 41 24 0.585365853658537 0.00366524129505192
TF TF:M11298 Factor: jdp2; motif: NRTGACGTCAYN 0.0332505863231067 1597 52 12 0.230769230769231 0.00751408891671885
TF TF:M11267 Factor: c-Jun; motif: NATGACKCATN 0.0332505863231067 3183 21 10 0.476190476190476 0.00314169022934339
TF TF:M11225 Factor: CREM; motif: NNTGACGTCANN 0.0334952592632837 2710 41 14 0.341463414634146 0.00516605166051661
TF TF:M11531_1 Factor: E2F-2; motif: GCGCGCGCGYW; match class: 1 0.0338136220374641 12351 54 45 0.833333333333333 0.00364342968180714
TF TF:M08930 Factor: JUND:FRA-1; motif: RTGACGTMAY 0.034886158524052 5702 59 29 0.491525423728814 0.00508593475973343
TF TF:M12160_1 Factor: KLF15; motif: RCCMCRCCCMCN; match class: 1 0.0373233409136932 8031 11 10 0.909090909090909 0.00124517494708006
TF TF:M12005_1 Factor: GMEB-1; motif: KNACGTNRNNACGTAN; match class: 1 0.0384576492692067 471 32 5 0.15625 0.0106157112526539
TF TF:M00338 Factor: ATF; motif: NTGACGTCANYS 0.0392715139582171 3798 59 22 0.372881355932203 0.00579252238020011
TF TF:M10072 Factor: sp4; motif: NNGNARGRGGCGGRGCNNRR 0.0392715139582171 10494 38 30 0.789473684210526 0.0028587764436821
TF TF:M11307_1 Factor: ATF-2; motif: NNTGACGTMANN; match class: 1 0.03944157626517 1946 33 10 0.303030303030303 0.00513874614594039
TF TF:M01104_1 Factor: MOVO-B; motif: GNGGGGG; match class: 1 0.0394580412413401 5626 37 20 0.540540540540541 0.00355492356914326
TF TF:M08947 Factor: C-FOS; motif: NNNKATGACGTCATNNN 0.0395661223014327 7042 52 30 0.576923076923077 0.00426015336552116
TF TF:M00215 Factor: SRF; motif: DCCWTATATGGNCWN 0.0395661223014327 147 59 4 0.0677966101694915 0.0272108843537415
TF TF:M01007 Factor: SRF; motif: CNKNKCCTTATWTGGNNNN 0.0396916141997298 256 59 5 0.0847457627118644 0.01953125
TF TF:M09723_1 Factor: BTEB1; motif: GGGGGCGGGGCNGSGGGNGS; match class: 1 0.0396916141997298 6113 37 21 0.567567567567568 0.00343530181580239
TF TF:M11257 Factor: AIBZIP; motif: NRTGACGTCAYN 0.0396916141997298 981 33 7 0.212121212121212 0.00713557594291539
TF TF:M11223_1 Factor: CREB1; motif: NRTGACGTCANN; match class: 1 0.0401771557908102 2678 52 16 0.307692307692308 0.00597460791635549
TF TF:M11541_1 Factor: Foxn2; motif: NNGCGTCNNNNNGACGCNN; match class: 1 0.0401771557908102 5493 59 28 0.474576271186441 0.00509739668669215
TF TF:M10071_1 Factor: Sp1; motif: NGGGGGCGGGGCCNGGGGGGGG; match class: 1 0.0401771557908102 4623 38 18 0.473684210526316 0.00389357560025957
TF TF:M11379_1 Factor: ESE-1; motif: ACCCGGAAGTRNNNNNNNNWWWW; match class: 1 0.0402090080542834 396 58 6 0.103448275862069 0.0151515151515152
TF TF:M11219 Factor: CREB1; motif: NRTGACGTR 0.0403415120213726 873 59 9 0.152542372881356 0.0103092783505155
TF TF:M00053_1 Factor: c-Rel; motif: SGGRNTTTCC; match class: 1 0.0403415120213726 426 10 3 0.3 0.00704225352112676
TF TF:M00114_1 Factor: Tax/CREB; motif: GGGGGTTGACGYANA; match class: 1 0.0408830832129117 1564 48 11 0.229166666666667 0.00703324808184143
TF TF:M08952 Factor: NF-KAPPAB1; motif: NGGKRNTTYCCCN 0.0414134711805001 7763 13 11 0.846153846153846 0.00141697797243334
TF TF:M08295 Factor: FOXO1A:Elf-1; motif: NAGAAAACCGAANM 0.0418635506824741 11711 13 13 1 0.00111006745794552
TF TF:M01862_1 Factor: ATF-2; motif: NNNTGACGTNAN; match class: 1 0.0421523843564481 1007 52 9 0.173076923076923 0.00893743793445879
TF TF:M11304_1 Factor: batf3; motif: NRTGAYGTCAYN; match class: 1 0.0423529646392222 730 33 6 0.181818181818182 0.00821917808219178
TF TF:M00051_1 Factor: NF-kappaB; motif: GGGGATYCCC; match class: 1 0.0423529646392222 2797 17 8 0.470588235294118 0.00286020736503396
TF TF:M08891 Factor: NFKAPPAB; motif: NNGGGANTTCCCN 0.0423529646392222 2110 17 7 0.411764705882353 0.0033175355450237
TF TF:M07297_1 Factor: MAZ; motif: CCCTCCCYCYN; match class: 1 0.0423529646392222 685 35 6 0.171428571428571 0.00875912408759124
TF TF:M07611_1 Factor: p54NRB; motif: GRNNNMGGATGRMNNCGGA; match class: 1 0.0424046288555393 1645 11 5 0.454545454545455 0.00303951367781155
TF TF:M12351_1 Factor: TIEG1; motif: NCCCNSNCCCCGCCCCC; match class: 1 0.0424046288555393 8180 37 25 0.675675675675676 0.00305623471882641
TF TF:M11273 Factor: JunB; motif: GATGACGTCAYC 0.0424046288555393 9017 50 34 0.68 0.0037706554286348
TF TF:M11309 Factor: ATF-2; motif: NRTGACGTMANN 0.0424229376534589 6429 52 28 0.538461538461538 0.00435526520454192
TF TF:M02281_1 Factor: SP1; motif: CCCCKCCCCC; match class: 1 0.0424229376534589 2558 11 6 0.545454545454545 0.00234558248631744
TF TF:M11384_1 Factor: ESE-1; motif: ACCCGGAAGTRNNNNNNNWWWWW; match class: 1 0.0424229376534589 408 58 6 0.103448275862069 0.0147058823529412
TF TF:M00933 Factor: Sp1; motif: CCCCGCCCCN 0.0424279912537079 9715 39 29 0.743589743589744 0.00298507462686567
TF TF:M01118_1 Factor: WT1; motif: SMCNCCNSC; match class: 1 0.0427915532335672 2766 25 10 0.4 0.00361532899493854
TF TF:M11254_1 Factor: AIBZIP; motif: GRTGAYGTCAYC; match class: 1 0.0428276495668126 742 33 6 0.181818181818182 0.00808625336927224
TF TF:M01973_1 Factor: PLAG1; motif: CCCCCKWNNNGGSCCC; match class: 1 0.0428276495668126 2398 48 14 0.291666666666667 0.00583819849874896
TF TF:M11313_1 Factor: CREBPA; motif: NRTGACGTMANN; match class: 1 0.0428276495668126 2025 33 10 0.303030303030303 0.00493827160493827
TF TF:M00986_1 Factor: Churchill; motif: CGGGNN; match class: 1 0.0429833930712647 10357 18 16 0.888888888888889 0.00154484889446751
TF TF:M11305 Factor: batf3; motif: NRTGACGTCAYN 0.0429833930712647 745 33 6 0.181818181818182 0.00805369127516779
TF TF:M11305_1 Factor: batf3; motif: NRTGACGTCAYN; match class: 1 0.0429833930712647 745 33 6 0.181818181818182 0.00805369127516779
TF TF:M11601_1 Factor: TCF-1; motif: ACATCGRGRCGCTGW; match class: 1 0.0436305554397168 11053 40 32 0.8 0.00289514159051841
TF TF:M11692_1 Factor: MEF-2C; motif: CCAWATWTRG; match class: 1 0.0451718656968649 162 59 4 0.0677966101694915 0.0246913580246914
TF TF:M00665 Factor: Sp3; motif: ASMCTTGGGSRGGG 0.0451718656968649 7729 10 9 0.9 0.00116444559451417
TF TF:M09989 Factor: MITF; motif: TCACGTGACC 0.0456353892774789 1381 19 6 0.315789473684211 0.00434467776973208
TF TF:M00490 Factor: Bach2; motif: SRTGAGTCANC 0.04605010410942 568 18 4 0.222222222222222 0.00704225352112676
TF TF:M00244_1 Factor: NGFI-C; motif: WTGCGTGGGYGG; match class: 1 0.04605010410942 1772 38 10 0.263157894736842 0.00564334085778781
TF TF:M11304 Factor: batf3; motif: NRTGAYGTCAYN 0.04605010410942 763 33 6 0.181818181818182 0.00786369593709043
TF TF:M11695 Factor: MEF-2D; motif: CCAWATWTRG 0.04605010410942 288 16 3 0.1875 0.0104166666666667
TF TF:M04519_1 Factor: E2F-4; motif: TTTGGCGCCAAA; match class: 1 0.04605010410942 2547 15 7 0.466666666666667 0.0027483313702395
TF TF:M02279 Factor: CREB1; motif: TGACGTCA 0.04605010410942 1731 52 12 0.230769230769231 0.00693240901213172
TF TF:M08472_1 Factor: Fli-1:E2A; motif: NCCGGAWRCASCTGN; match class: 1 0.04605010410942 2240 3 3 1 0.00133928571428571
TF TF:M09658 Factor: Sp2; motif: GGSNNGGGGGCGGGGCCNGNGS 0.04605010410942 5262 54 25 0.462962962962963 0.00475104522995059
TF TF:M11251_1 Factor: Luman; motif: NRTGACGTCAYN; match class: 1 0.0465429309317678 768 33 6 0.181818181818182 0.0078125
TF TF:M04148 Factor: TFAP2A; motif: NGCCCYNNGGGCN 0.0468343316486887 10040 40 30 0.75 0.00298804780876494
TF TF:M04194 Factor: TFEB; motif: RNCACGTGAC 0.0468343316486887 1436 25 7 0.28 0.00487465181058496
TF TF:M08803 Factor: CREM; motif: NNTGACGT 0.0468343316486887 1124 49 9 0.183673469387755 0.00800711743772242
TF TF:M03893_1 Factor: WT1; motif: GNGGGGGCGGGG; match class: 1 0.0468343316486887 3980 48 19 0.395833333333333 0.00477386934673367
TF TF:M00483_1 Factor: ATF6; motif: TGACGTGG; match class: 1 0.0468343316486887 246 19 3 0.157894736842105 0.0121951219512195
TF TF:M11307 Factor: ATF-2; motif: NNTGACGTMANN 0.0468343316486887 2085 33 10 0.303030303030303 0.00479616306954436
TF TF:M00444 Factor: VDR; motif: GGGKNARNRRGGWSA 0.0468343316486887 10308 14 13 0.928571428571429 0.00126115638339154
TF TF:M08692_1 Factor: ERF:pitx1; motif: NNCGGAWGNNNRGNTTA; match class: 1 0.0470458064825208 884 6 3 0.5 0.00339366515837104
TF TF:M11251 Factor: Luman; motif: NRTGACGTCAYN 0.0481048652347018 780 33 6 0.181818181818182 0.00769230769230769
TF TF:M11843 Factor: ER-alpha; motif: NAGGTCACSGTGACCTN 0.0481182794224467 3743 14 8 0.571428571428571 0.00213732300293882
TF TF:M01203_1 Factor: SPI1; motif: NNAAWGNGGAASTNNNN; match class: 1 0.0485303361346193 211 48 4 0.0833333333333333 0.018957345971564
TF TF:M04744_1 Factor: ATF-3; motif: GGCGCSSNSNGRTSACGTSA; match class: 1 0.0485303361346193 4889 52 23 0.442307692307692 0.00470443853548783
TF TF:M00236 Factor: Arnt; motif: NDDNNCACGTGNNNNN 0.0489956421278449 2210 59 15 0.254237288135593 0.00678733031674208
TF TF:M12345_1 Factor: Zbtb37; motif: NYACCGCRNTCACCGCR; match class: 1 0.0489956421278449 1688 34 9 0.264705882352941 0.00533175355450237
TF TF:M00039 Factor: CREB; motif: TGACGTMA 0.0489956421278449 5222 52 24 0.461538461538462 0.00459594025277671
TF TF:M00186 Factor: SRF; motif: GNCCAWATAWGGMN 0.0489956421278449 172 59 4 0.0677966101694915 0.0232558139534884
TF TF:M11531 Factor: E2F-2; motif: GCGCGCGCGYW 0.0498268176610709 13270 42 37 0.880952380952381 0.00278824415975885
TF TF:M11313 Factor: CREBPA; motif: NRTGACGTMANN 0.0498268176610709 3680 52 19 0.365384615384615 0.00516304347826087
TF TF:M11271_1 Factor: JunD; motif: NRTGACGCAYN; match class: 1 0.0498268176610709 1497 53 11 0.207547169811321 0.00734802939211757
TF TF:M09668_1 Factor: RelA-p65; motif: GGGRNTTTCCM; match class: 1 0.0499001783730277 513 10 3 0.3 0.00584795321637427
WP WP:WP2355 Corticotropin-releasing hormone signaling pathway 8.75494544807228e-05 91 27 6 0.222222222222222 0.0659340659340659
WP WP:WP2374 Oncostatin M Signaling Pathway 0.00021349232427779 66 27 5 0.185185185185185 0.0757575757575758
WP WP:WP366 TGF-beta Signaling Pathway 0.000271461003930042 133 27 6 0.222222222222222 0.0451127819548872
WP WP:WP4754 IL-18 signaling pathway 0.00129338442860975 279 57 10 0.175438596491228 0.03584229390681
WP WP:WP2431 Spinal Cord Injury 0.001398556375585 118 6 3 0.5 0.0254237288135593
WP WP:WP3611 Photodynamic therapy-induced AP-1 survival signaling. 0.001398556375585 51 13 3 0.230769230769231 0.0588235294117647
WP WP:WP3527 Preimplantation Embryo 0.00292333914214442 60 16 3 0.1875 0.05
WP WP:WP1772 Apoptosis Modulation and Signaling 0.00447151326779952 93 13 3 0.230769230769231 0.032258064516129
WP WP:WP3613 Photodynamic therapy-induced unfolded protein response 0.00447151326779952 29 41 3 0.0731707317073171 0.103448275862069
WP WP:WP1449 Regulation of toll-like receptor signaling pathway 0.00592088634751232 145 10 3 0.3 0.0206896551724138
WP WP:WP3614 Photodynamic therapy-induced HIF-1 survival signaling 0.00786353376088523 37 43 3 0.0697674418604651 0.0810810810810811
WP WP:WP4659 Gastrin Signaling Pathway 0.00919714398111631 114 16 3 0.1875 0.0263157894736842
WP WP:WP2380 Brain-Derived Neurotrophic Factor (BDNF) signaling pathway 0.0121933491581589 144 16 3 0.1875 0.0208333333333333
WP WP:WP2882 Nuclear Receptors Meta-Pathway 0.0121933491581589 321 35 6 0.171428571428571 0.0186915887850467
WP WP:WP254 Apoptosis 0.0207303366323265 86 36 3 0.0833333333333333 0.0348837209302326

pTNI01 transcription factor target enrichment of top program genes

TF enrichment of pTNI01
TFs corrosponding to activation of pTNI01. (Left) pearson correlation of TF expression and gene expression program activatity in T/NK/ILC cells, (right) negative log p-value for enrichment of TF binding sites among top uniqueness weighted genes for the gene program. Blue bars indicate significant TFs meeting the following criteria: FDR<0.1, overlap > 2, Corr. R > 0, permutation based p-value < 0.05.