pEpi32 program activity among Epithelial cells

Activation of pEpi32
pEpi32 gene program activation in Epithelial cells. (Top) Activation of program across all epithelial cells. (Bottom) Activation in MMRd (left), MMRp (middle), and normal epithelial cells (right).

Epithelial cell compositional overview

Overview of epithelial cell composition
Overview of epithelial cell composition. A tSNE plot colored by: (left) MMR status of epithelial cells, (middle) specimen, (righ) epithelial cell sub-type.
Gene program activation of pEpi32 by different cell subtypes
pEpi32 gene program activation among cells of different subtypes (Epithelial cells).

pEpi32 top program genes

Top genes of pEpi32 program
Bar plots showing the top genes for each gene program, ranked by (left) unique weights, (right) raw weights.

pEpi32 gene-set enrichment of top program genes (using g-profiler)

GSEA wth gene profiler of pEpi32
pEpi32 gene-set enrichment summary using g-profiler webtool.
Source termID Name Padj Tsize Qsize Overlap Precision Recall
CORUM CORUM:10 Condensin I complex 3.60536678076356e-06 5 136 5 0.0367647058823529 1
CORUM CORUM:157 Condensin I complex 3.60536678076356e-06 5 136 5 0.0367647058823529 1
CORUM CORUM:167 Condensin I complex 3.60536678076356e-06 5 136 5 0.0367647058823529 1
CORUM CORUM:7479 Astrin-kinastrin complex 3.60536678076356e-06 5 109 5 0.0458715596330275 1
CORUM CORUM:159 Condensin I-PARP-1-XRCC1 complex 5.69751846526526e-05 7 136 5 0.0367647058823529 0.714285714285714
CORUM CORUM:7439 ECT2-KIF23-RACGAP1 complex 0.00019687822534523 3 69 3 0.0434782608695652 1
CORUM CORUM:2582 Chromosomal passenger complex CPC (CDCA8, AURKB, BIRC5) 0.00019687822534523 3 68 3 0.0441176470588235 1
CORUM CORUM:310 Cell cycle kinase complex CDC2 0.000385977399161867 6 34 3 0.0882352941176471 0.5
CORUM CORUM:1118 Chromosomal passenger complex CPC (INCENP, CDCA8, BIRC5, AURKB) 0.000520198132140761 4 68 3 0.0441176470588235 0.75
CORUM CORUM:1119 Chromosomal passenger complex CPC (INCENP, CDCA8, BIRC5, AURKB) 0.000520198132140761 4 68 3 0.0441176470588235 0.75
CORUM CORUM:127 NDC80 kinetochore complex 0.00088188828227429 4 86 3 0.0348837209302326 0.75
CORUM CORUM:190 Mitotic checkpoint complex (MCC) 0.00165400070781326 4 119 3 0.0252100840336134 0.75
CORUM CORUM:1005 RC complex during G2/M-phase of cell cycle 0.00234516788026808 13 34 3 0.0882352941176471 0.230769230769231
CORUM CORUM:49 DNMT3B complex 0.004680333463125 7 103 3 0.029126213592233 0.428571428571429
CORUM CORUM:7388 CENP-A nucleosomal complex 0.0277244577134956 14 101 3 0.0297029702970297 0.214285714285714
GO:BP GO:0051301 cell division 4.86448101977827e-79 622 122 77 0.631147540983607 0.12379421221865
GO:BP GO:0000278 mitotic cell cycle 1.03705374146302e-70 1059 121 83 0.685950413223141 0.0783758262511804
GO:BP GO:0007049 cell cycle 1.80162360749319e-68 1902 123 97 0.788617886178862 0.0509989484752892
GO:BP GO:1903047 mitotic cell cycle process 6.43240461757051e-67 911 121 77 0.636363636363636 0.0845225027442371
GO:BP GO:0007059 chromosome segregation 2.50112202521771e-62 334 122 56 0.459016393442623 0.167664670658683
GO:BP GO:0140014 mitotic nuclear division 9.40297102506223e-62 302 121 54 0.446280991735537 0.178807947019868
GO:BP GO:0022402 cell cycle process 1.11523507772253e-60 1439 123 84 0.682926829268293 0.0583738707435719
GO:BP GO:0000280 nuclear division 1.79957303788617e-58 448 121 58 0.479338842975207 0.129464285714286
GO:BP GO:0048285 organelle fission 8.24032719581246e-56 497 121 58 0.479338842975207 0.116700201207243
GO:BP GO:0000819 sister chromatid segregation 8.82293925983742e-51 193 121 42 0.347107438016529 0.217616580310881
GO:BP GO:0000070 mitotic sister chromatid segregation 2.1228839803497e-50 164 121 40 0.330578512396694 0.24390243902439
GO:BP GO:0098813 nuclear chromosome segregation 2.2591713669966e-47 272 121 44 0.363636363636364 0.161764705882353
GO:BP GO:1902850 microtubule cytoskeleton organization involved in mitosis 3.46558137622209e-40 149 116 33 0.28448275862069 0.221476510067114
GO:BP GO:0000226 microtubule cytoskeleton organization 4.64481034029779e-38 613 121 49 0.40495867768595 0.0799347471451876
GO:BP GO:0007017 microtubule-based process 9.50638331218902e-38 881 121 55 0.454545454545455 0.0624290578887628
GO:BP GO:0007051 spindle organization 6.40115296209223e-36 187 110 32 0.290909090909091 0.171122994652406
GO:BP GO:0007052 mitotic spindle organization 5.10623113588408e-35 122 110 28 0.254545454545455 0.229508196721311
GO:BP GO:0051726 regulation of cell cycle 8.62041219770599e-35 1236 120 59 0.491666666666667 0.0477346278317152
GO:BP GO:0051276 chromosome organization 3.21346900731895e-34 1258 125 60 0.48 0.0476947535771065
GO:BP GO:0006996 organelle organization 1.24561765167882e-33 4104 121 92 0.760330578512397 0.0224171539961014
GO:BP GO:0010564 regulation of cell cycle process 1.13320007594075e-32 809 120 49 0.408333333333333 0.0605686032138443
GO:BP GO:0044772 mitotic cell cycle phase transition 4.57407305523316e-26 609 120 39 0.325 0.0640394088669951
GO:BP GO:0044770 cell cycle phase transition 5.6688180659406e-26 658 120 40 0.333333333333333 0.060790273556231
GO:BP GO:0007346 regulation of mitotic cell cycle 1.10407910680157e-24 619 120 38 0.316666666666667 0.061389337641357
GO:BP GO:0007010 cytoskeleton organization 3.24713939040771e-23 1423 121 51 0.421487603305785 0.0358397751229796
GO:BP GO:0051983 regulation of chromosome segregation 2.41586472374266e-22 86 119 19 0.159663865546218 0.22093023255814
GO:BP GO:0007088 regulation of mitotic nuclear division 1.11545503477732e-21 111 119 20 0.168067226890756 0.18018018018018
GO:BP GO:0010965 regulation of mitotic sister chromatid separation 1.47328169445067e-21 63 119 17 0.142857142857143 0.26984126984127
GO:BP GO:0051304 chromosome separation 2.11265664425334e-21 96 119 19 0.159663865546218 0.197916666666667
GO:BP GO:0051306 mitotic sister chromatid separation 2.50861429426376e-21 65 119 17 0.142857142857143 0.261538461538462
GO:BP GO:1901987 regulation of cell cycle phase transition 3.183565427543e-21 493 120 32 0.266666666666667 0.0649087221095335
GO:BP GO:1905818 regulation of chromosome separation 9.36465530722309e-21 70 119 17 0.142857142857143 0.242857142857143
GO:BP GO:0033045 regulation of sister chromatid segregation 9.36465530722309e-21 70 119 17 0.142857142857143 0.242857142857143
GO:BP GO:1901990 regulation of mitotic cell cycle phase transition 3.81751933679796e-20 451 130 31 0.238461538461538 0.0687361419068736
GO:BP GO:0051640 organelle localization 3.81751933679796e-20 668 130 36 0.276923076923077 0.0538922155688623
GO:BP GO:0007091 metaphase/anaphase transition of mitotic cell cycle 4.04718789045531e-20 61 119 16 0.134453781512605 0.262295081967213
GO:BP GO:0051783 regulation of nuclear division 6.87737518456176e-20 137 119 20 0.168067226890756 0.145985401459854
GO:BP GO:0044784 metaphase/anaphase transition of cell cycle 9.08825274658999e-20 64 119 16 0.134453781512605 0.25
GO:BP GO:0051310 metaphase plate congression 1.54560674915134e-19 65 121 16 0.132231404958678 0.246153846153846
GO:BP GO:0051303 establishment of chromosome localization 2.00643207347134e-19 82 121 17 0.140495867768595 0.207317073170732
GO:BP GO:0050000 chromosome localization 3.05282538616486e-19 84 121 17 0.140495867768595 0.202380952380952
GO:BP GO:0051225 spindle assembly 6.20829575143544e-19 117 110 18 0.163636363636364 0.153846153846154
GO:BP GO:0030071 regulation of mitotic metaphase/anaphase transition 1.16489270734064e-18 59 119 15 0.126050420168067 0.254237288135593
GO:BP GO:0033043 regulation of organelle organization 1.76894571618856e-18 1203 125 43 0.344 0.0357439733998337
GO:BP GO:0008608 attachment of spindle microtubules to kinetochore 2.12426052308712e-18 36 119 13 0.109243697478992 0.361111111111111
GO:BP GO:1902099 regulation of metaphase/anaphase transition of cell cycle 2.49893503833816e-18 62 119 15 0.126050420168067 0.241935483870968
GO:BP GO:0016043 cellular component organization 3.27094642511827e-18 6566 121 93 0.768595041322314 0.0141638745050259
GO:BP GO:0000910 cytokinesis 3.47793306786254e-18 174 98 19 0.193877551020408 0.109195402298851
GO:BP GO:0045787 positive regulation of cell cycle 1.20463465907992e-17 403 114 26 0.228070175438596 0.0645161290322581
GO:BP GO:2000816 negative regulation of mitotic sister chromatid separation 1.96472325595086e-17 42 119 13 0.109243697478992 0.30952380952381
GO:BP GO:0033048 negative regulation of mitotic sister chromatid segregation 1.96472325595086e-17 42 119 13 0.109243697478992 0.30952380952381
GO:BP GO:0033046 negative regulation of sister chromatid segregation 1.96472325595086e-17 42 119 13 0.109243697478992 0.30952380952381
GO:BP GO:0071840 cellular component organization or biogenesis 2.78371824628402e-17 6760 121 93 0.768595041322314 0.0137573964497041
GO:BP GO:0051985 negative regulation of chromosome segregation 3.73802075684612e-17 44 119 13 0.109243697478992 0.295454545454545
GO:BP GO:1905819 negative regulation of chromosome separation 3.73802075684612e-17 44 119 13 0.109243697478992 0.295454545454545
GO:BP GO:0033047 regulation of mitotic sister chromatid segregation 5.13463489187883e-17 45 119 13 0.109243697478992 0.288888888888889
GO:BP GO:0033044 regulation of chromosome organization 5.77967361193014e-17 279 125 23 0.184 0.0824372759856631
GO:BP GO:0051321 meiotic cell cycle 5.77967361193014e-17 254 121 22 0.181818181818182 0.0866141732283465
GO:BP GO:0090068 positive regulation of cell cycle process 6.29849100615259e-17 309 114 23 0.201754385964912 0.0744336569579288
GO:BP GO:1903046 meiotic cell cycle process 8.05514783872044e-17 195 121 20 0.165289256198347 0.102564102564103
GO:BP GO:0044839 cell cycle G2/M phase transition 1.89902645771859e-16 283 130 23 0.176923076923077 0.0812720848056537
GO:BP GO:0061640 cytoskeleton-dependent cytokinesis 2.70214846897464e-16 102 98 15 0.153061224489796 0.147058823529412
GO:BP GO:0007080 mitotic metaphase plate congression 2.70214846897464e-16 50 121 13 0.107438016528926 0.26
GO:BP GO:0045841 negative regulation of mitotic metaphase/anaphase transition 5.94285139221762e-16 40 119 12 0.100840336134454 0.3
GO:BP GO:0000086 G2/M transition of mitotic cell cycle 6.38102756147999e-16 265 130 22 0.169230769230769 0.0830188679245283
GO:BP GO:0051383 kinetochore organization 7.99230069326538e-16 23 103 10 0.0970873786407767 0.434782608695652
GO:BP GO:2001251 negative regulation of chromosome organization 1.02697919922188e-15 92 119 15 0.126050420168067 0.16304347826087
GO:BP GO:1902100 negative regulation of metaphase/anaphase transition of cell cycle 1.0950297354734e-15 42 119 12 0.100840336134454 0.285714285714286
GO:BP GO:0000281 mitotic cytokinesis 3.74834047666498e-15 74 98 13 0.13265306122449 0.175675675675676
GO:BP GO:1902749 regulation of cell cycle G2/M phase transition 4.26340791187707e-15 223 130 20 0.153846153846154 0.0896860986547085
GO:BP GO:0051656 establishment of organelle localization 5.3093290876338e-15 445 121 25 0.206611570247934 0.0561797752808989
GO:BP GO:0090307 mitotic spindle assembly 5.3093290876338e-15 68 110 13 0.118181818181818 0.191176470588235
GO:BP GO:0140013 meiotic nuclear division 5.32876731852126e-15 179 121 18 0.148760330578512 0.100558659217877
GO:BP GO:0045839 negative regulation of mitotic nuclear division 6.134735531655e-15 48 119 12 0.100840336134454 0.25
GO:BP GO:0070925 organelle assembly 1.43203061897825e-14 895 130 34 0.261538461538462 0.0379888268156425
GO:BP GO:0010389 regulation of G2/M transition of mitotic cell cycle 1.55291392710549e-14 207 130 19 0.146153846153846 0.0917874396135266
GO:BP GO:0007094 mitotic spindle assembly checkpoint 1.74741675559215e-14 38 119 11 0.092436974789916 0.289473684210526
GO:BP GO:0071174 mitotic spindle checkpoint 1.74741675559215e-14 38 119 11 0.092436974789916 0.289473684210526
GO:BP GO:0071173 spindle assembly checkpoint 1.74741675559215e-14 38 119 11 0.092436974789916 0.289473684210526
GO:BP GO:0031577 spindle checkpoint 2.3903321110025e-14 39 119 11 0.092436974789916 0.282051282051282
GO:BP GO:0051784 negative regulation of nuclear division 3.39673092570298e-14 55 119 12 0.100840336134454 0.218181818181818
GO:BP GO:0007093 mitotic cell cycle checkpoint 3.09164652336312e-13 164 119 16 0.134453781512605 0.0975609756097561
GO:BP GO:0031145 anaphase-promoting complex-dependent catabolic process 8.9023747415333e-13 85 34 9 0.264705882352941 0.105882352941176
GO:BP GO:0051988 regulation of attachment of spindle microtubules to kinetochore 2.01469222474795e-11 14 109 7 0.0642201834862385 0.5
GO:BP GO:0000075 cell cycle checkpoint 2.2254212886473e-11 216 119 16 0.134453781512605 0.0740740740740741
GO:BP GO:0032465 regulation of cytokinesis 2.66297420756108e-11 89 94 11 0.117021276595745 0.123595505617978
GO:BP GO:0045132 meiotic chromosome segregation 7.98258124157327e-11 93 72 10 0.138888888888889 0.10752688172043
GO:BP GO:0045786 negative regulation of cell cycle 1.35562555925753e-10 647 64 18 0.28125 0.0278207109737249
GO:BP GO:1901991 negative regulation of mitotic cell cycle phase transition 4.02955881797049e-10 262 119 16 0.134453781512605 0.0610687022900763
GO:BP GO:0051641 cellular localization 4.09272386929955e-10 3541 133 60 0.451127819548872 0.0169443659983056
GO:BP GO:0006323 DNA packaging 4.88870681532324e-10 241 111 15 0.135135135135135 0.0622406639004149
GO:BP GO:0010948 negative regulation of cell cycle process 5.22689191665069e-10 372 62 14 0.225806451612903 0.0376344086021505
GO:BP GO:0051128 regulation of cellular component organization 6.40251526377913e-10 2412 125 46 0.368 0.0190713101160862
GO:BP GO:0032506 cytokinetic process 6.79494235231596e-10 39 98 8 0.0816326530612245 0.205128205128205
GO:BP GO:0051256 mitotic spindle midzone assembly 9.46029375718603e-10 8 70 5 0.0714285714285714 0.625
GO:BP GO:1901988 negative regulation of cell cycle phase transition 1.06700929563222e-09 281 119 16 0.134453781512605 0.0569395017793594
GO:BP GO:1904666 regulation of ubiquitin protein ligase activity 1.11965393821747e-09 25 20 5 0.25 0.2
GO:BP GO:0030261 chromosome condensation 1.11965393821747e-09 46 136 9 0.0661764705882353 0.195652173913043
GO:BP GO:0034508 centromere complex assembly 1.13566568185379e-09 56 111 9 0.0810810810810811 0.160714285714286
GO:BP GO:0051382 kinetochore assembly 1.13566568185379e-09 18 71 6 0.0845070422535211 0.333333333333333
GO:BP GO:0040001 establishment of mitotic spindle localization 1.24128536052337e-09 36 116 8 0.0689655172413793 0.222222222222222
GO:BP GO:0045930 negative regulation of mitotic cell cycle 1.32328934828531e-09 333 119 17 0.142857142857143 0.0510510510510511
GO:BP GO:0051653 spindle localization 1.64149559678492e-09 56 116 9 0.0775862068965517 0.160714285714286
GO:BP GO:0000022 mitotic spindle elongation 1.9200866482486e-09 9 70 5 0.0714285714285714 0.555555555555556
GO:BP GO:0051231 spindle elongation 1.9200866482486e-09 9 70 5 0.0714285714285714 0.555555555555556
GO:BP GO:0051302 regulation of cell division 2.08188397783686e-09 174 94 12 0.127659574468085 0.0689655172413793
GO:BP GO:0000079 regulation of cyclin-dependent protein serine/threonine kinase activity 2.57015267522963e-09 99 28 7 0.25 0.0707070707070707
GO:BP GO:0071103 DNA conformation change 2.94939181610463e-09 355 118 17 0.144067796610169 0.047887323943662
GO:BP GO:1904029 regulation of cyclin-dependent protein kinase activity 3.34426296993439e-09 103 28 7 0.25 0.0679611650485437
GO:BP GO:0071459 protein localization to chromosome, centromeric region 3.80356281218108e-09 25 119 7 0.0588235294117647 0.28
GO:BP GO:0010639 negative regulation of organelle organization 4.2481538061098e-09 361 62 13 0.209677419354839 0.03601108033241
GO:BP GO:0070507 regulation of microtubule cytoskeleton organization 4.70055668481962e-09 145 121 12 0.0991735537190083 0.0827586206896552
GO:BP GO:0061982 meiosis I cell cycle process 9.47949349195359e-09 128 114 11 0.0964912280701754 0.0859375
GO:BP GO:0051255 spindle midzone assembly 1.10168733694049e-08 12 70 5 0.0714285714285714 0.416666666666667
GO:BP GO:1904668 positive regulation of ubiquitin protein ligase activity 1.16110264843899e-08 13 19 4 0.210526315789474 0.307692307692308
GO:BP GO:0000132 establishment of mitotic spindle orientation 1.24161013206934e-08 30 116 7 0.0603448275862069 0.233333333333333
GO:BP GO:0007127 meiosis I 1.49297629999937e-08 123 94 10 0.106382978723404 0.0813008130081301
GO:BP GO:0034502 protein localization to chromosome 1.55982314861077e-08 93 125 10 0.08 0.10752688172043
GO:BP GO:0051338 regulation of transferase activity 1.91909201552756e-08 1035 44 16 0.363636363636364 0.0154589371980676
GO:BP GO:0032467 positive regulation of cytokinesis 1.96422723253504e-08 39 94 7 0.074468085106383 0.179487179487179
GO:BP GO:0051293 establishment of spindle localization 2.01329525092046e-08 51 116 8 0.0689655172413793 0.156862745098039
GO:BP GO:0050790 regulation of catalytic activity 2.14770127430662e-08 2545 20 15 0.75 0.00589390962671906
GO:BP GO:0007076 mitotic chromosome condensation 2.14770127430662e-08 16 136 6 0.0441176470588235 0.375
GO:BP GO:0007062 sister chromatid cohesion 2.40994903274904e-08 56 108 8 0.0740740740740741 0.142857142857143
GO:BP GO:0097711 ciliary basal body-plasma membrane docking 2.67628884314202e-08 95 130 10 0.0769230769230769 0.105263157894737
GO:BP GO:0019886 antigen processing and presentation of exogenous peptide antigen via MHC class II 2.94592216238549e-08 96 130 10 0.0769230769230769 0.104166666666667
GO:BP GO:0034501 protein localization to kinetochore 3.06472634080298e-08 19 119 6 0.0504201680672269 0.315789473684211
GO:BP GO:0051347 positive regulation of transferase activity 3.47270981941755e-08 689 94 19 0.202127659574468 0.0275761973875181
GO:BP GO:0002495 antigen processing and presentation of peptide antigen via MHC class II 4.31027445482936e-08 100 130 10 0.0769230769230769 0.1
GO:BP GO:0051294 establishment of spindle orientation 4.4013300817206e-08 36 116 7 0.0603448275862069 0.194444444444444
GO:BP GO:0051438 regulation of ubiquitin-protein transferase activity 5.32162375048166e-08 55 20 5 0.25 0.0909090909090909
GO:BP GO:0002504 antigen processing and presentation of peptide or polysaccharide antigen via MHC class II 5.63761781242184e-08 103 130 10 0.0769230769230769 0.0970873786407767
GO:BP GO:0090224 regulation of spindle organization 6.07947154584694e-08 40 109 7 0.0642201834862385 0.175
GO:BP GO:0022607 cellular component assembly 6.75547490865649e-08 3010 71 33 0.464788732394366 0.0109634551495017
GO:BP GO:0051649 establishment of localization in cell 7.488344977329e-08 2813 90 37 0.411111111111111 0.0131532172058301
GO:BP GO:0007077 mitotic nuclear envelope disassembly 8.09510165071017e-08 12 34 4 0.117647058823529 0.333333333333333
GO:BP GO:0007143 female meiotic nuclear division 9.05390402214985e-08 28 94 6 0.0638297872340425 0.214285714285714
GO:BP GO:0051315 attachment of mitotic spindle microtubules to kinetochore 9.76835054920598e-08 15 86 5 0.0581395348837209 0.333333333333333
GO:BP GO:0044085 cellular component biogenesis 1.16980544619167e-07 3257 71 34 0.47887323943662 0.0104390543444888
GO:BP GO:0032886 regulation of microtubule-based process 1.20233181863052e-07 240 121 13 0.107438016528926 0.0541666666666667
GO:BP GO:0000915 actomyosin contractile ring assembly 1.83417224634561e-07 6 98 4 0.0408163265306122 0.666666666666667
GO:BP GO:0000912 assembly of actomyosin apparatus involved in cytokinesis 1.83417224634561e-07 6 98 4 0.0408163265306122 0.666666666666667
GO:BP GO:0030397 membrane disassembly 2.78493419261413e-07 16 34 4 0.117647058823529 0.25
GO:BP GO:0051081 nuclear envelope disassembly 2.78493419261413e-07 16 34 4 0.117647058823529 0.25
GO:BP GO:0032268 regulation of cellular protein metabolic process 2.78493419261413e-07 2541 20 14 0.7 0.00550964187327824
GO:BP GO:0022414 reproductive process 2.78522586158067e-07 1493 125 31 0.248 0.0207635632953784
GO:BP GO:0051642 centrosome localization 2.80863888512114e-07 33 46 5 0.108695652173913 0.151515151515152
GO:BP GO:0000003 reproduction 2.8786702036723e-07 1496 125 31 0.248 0.0207219251336898
GO:BP GO:0065009 regulation of molecular function 2.93254232751085e-07 3221 61 30 0.491803278688525 0.00931387767773983
GO:BP GO:0060236 regulation of mitotic spindle organization 3.18003565508047e-07 36 90 6 0.0666666666666667 0.166666666666667
GO:BP GO:0061842 microtubule organizing center localization 3.19961218771243e-07 34 46 5 0.108695652173913 0.147058823529412
GO:BP GO:0044837 actomyosin contractile ring organization 3.98157868190552e-07 7 98 4 0.0408163265306122 0.571428571428571
GO:BP GO:0043161 proteasome-mediated ubiquitin-dependent protein catabolic process 5.17024980869527e-07 434 23 8 0.347826086956522 0.0184331797235023
GO:BP GO:0051443 positive regulation of ubiquitin-protein transferase activity 5.54611260210528e-07 34 19 4 0.210526315789474 0.117647058823529
GO:BP GO:0007018 microtubule-based movement 5.67189280539632e-07 383 121 15 0.12396694214876 0.0391644908616188
GO:BP GO:0051246 regulation of protein metabolic process 5.84557942453509e-07 2704 20 14 0.7 0.00517751479289941
GO:BP GO:0043085 positive regulation of catalytic activity 1.00078786870641e-06 1418 97 25 0.257731958762887 0.0176304654442877
GO:BP GO:0007135 meiosis II 1.00078786870641e-06 11 72 4 0.0555555555555556 0.363636363636364
GO:BP GO:0045144 meiotic sister chromatid segregation 1.00078786870641e-06 11 72 4 0.0555555555555556 0.363636363636364
GO:BP GO:0061983 meiosis II cell cycle process 1.00078786870641e-06 11 72 4 0.0555555555555556 0.363636363636364
GO:BP GO:0051177 meiotic sister chromatid cohesion 1.00078786870641e-06 11 72 4 0.0555555555555556 0.363636363636364
GO:BP GO:0043486 histone exchange 1.06232056841668e-06 60 111 7 0.0630630630630631 0.116666666666667
GO:BP GO:0043044 ATP-dependent chromatin remodeling 1.14417923705195e-06 91 111 8 0.0720720720720721 0.0879120879120879
GO:BP GO:0016572 histone phosphorylation 1.20213260626827e-06 38 54 5 0.0925925925925926 0.131578947368421
GO:BP GO:0010498 proteasomal protein catabolic process 1.24214016350948e-06 491 23 8 0.347826086956522 0.0162932790224033
GO:BP GO:0031109 microtubule polymerization or depolymerization 1.24568704264867e-06 118 121 9 0.0743801652892562 0.076271186440678
GO:BP GO:0007292 female gamete generation 1.26933325068526e-06 140 30 6 0.2 0.0428571428571429
GO:BP GO:0006890 retrograde vesicle-mediated transport, Golgi to endoplasmic reticulum 1.52675199673307e-06 87 121 8 0.0661157024793388 0.0919540229885057
GO:BP GO:0051171 regulation of nitrogen compound metabolic process 1.67953318236897e-06 5848 20 18 0.9 0.00307797537619699
GO:BP GO:0070192 chromosome organization involved in meiotic cell cycle 2.10023218395402e-06 69 107 7 0.0654205607476635 0.101449275362319
GO:BP GO:0007098 centrosome cycle 2.59348268022409e-06 130 120 9 0.075 0.0692307692307692
GO:BP GO:0090306 spindle assembly involved in meiosis 2.88523006382658e-06 8 30 3 0.1 0.375
GO:BP GO:0061641 CENP-A containing chromatin organization 2.924935059318e-06 43 111 6 0.0540540540540541 0.13953488372093
GO:BP GO:0034080 CENP-A containing nucleosome assembly 2.924935059318e-06 43 111 6 0.0540540540540541 0.13953488372093
GO:BP GO:0080090 regulation of primary metabolic process 2.92595761667841e-06 6053 20 18 0.9 0.0029737320337023
GO:BP GO:0044771 meiotic cell cycle phase transition 3.74310161449314e-06 10 114 4 0.0350877192982456 0.4
GO:BP GO:0031399 regulation of protein modification process 3.74310161449314e-06 1671 20 11 0.55 0.00658288450029922
GO:BP GO:0051781 positive regulation of cell division 4.11072169000809e-06 87 94 7 0.074468085106383 0.0804597701149425
GO:BP GO:0031055 chromatin remodeling at centromere 4.30378907765538e-06 46 111 6 0.0540540540540541 0.130434782608696
GO:BP GO:0044093 positive regulation of molecular function 4.46768064134326e-06 1771 97 27 0.278350515463918 0.0152456239412761
GO:BP GO:0031323 regulation of cellular metabolic process 5.14820212676664e-06 6269 20 18 0.9 0.00287127133514117
GO:BP GO:0031023 microtubule organizing center organization 5.17279841590973e-06 142 120 9 0.075 0.0633802816901408
GO:BP GO:0140056 organelle localization by membrane tethering 6.01392152257501e-06 174 130 10 0.0769230769230769 0.0574712643678161
GO:BP GO:0002478 antigen processing and presentation of exogenous peptide antigen 6.01392152257501e-06 174 130 10 0.0769230769230769 0.0574712643678161
GO:BP GO:0051129 negative regulation of cellular component organization 7.32818889944905e-06 759 26 9 0.346153846153846 0.0118577075098814
GO:BP GO:0019884 antigen processing and presentation of exogenous antigen 8.99134226044183e-06 182 130 10 0.0769230769230769 0.0549450549450549
GO:BP GO:0045859 regulation of protein kinase activity 9.12872075379303e-06 809 94 17 0.180851063829787 0.0210135970333745
GO:BP GO:0022406 membrane docking 9.3532441817014e-06 183 130 10 0.0769230769230769 0.0546448087431694
GO:BP GO:0006336 DNA replication-independent nucleosome assembly 9.64867204656606e-06 53 111 6 0.0540540540540541 0.113207547169811
GO:BP GO:0006511 ubiquitin-dependent protein catabolic process 9.69986091882355e-06 655 23 8 0.347826086956522 0.0122137404580153
GO:BP GO:0019941 modification-dependent protein catabolic process 1.04548631875682e-05 662 23 8 0.347826086956522 0.0120845921450151
GO:BP GO:0034724 DNA replication-independent nucleosome organization 1.06321982640607e-05 54 111 6 0.0540540540540541 0.111111111111111
GO:BP GO:0008315 G2/MI transition of meiotic cell cycle 1.08886930379055e-05 4 114 3 0.0263157894736842 0.75
GO:BP GO:0060255 regulation of macromolecule metabolic process 1.15947833362725e-05 6603 20 18 0.9 0.00272603362108133
GO:BP GO:0043632 modification-dependent macromolecule catabolic process 1.15947833362725e-05 673 23 8 0.347826086956522 0.011887072808321
GO:BP GO:0048002 antigen processing and presentation of peptide antigen 1.38978431829852e-05 192 130 10 0.0769230769230769 0.0520833333333333
GO:BP GO:0000212 meiotic spindle organization 1.62645490598026e-05 14 30 3 0.1 0.214285714285714
GO:BP GO:0007163 establishment or maintenance of cell polarity 1.6589118311428e-05 220 116 10 0.0862068965517241 0.0454545454545455
GO:BP GO:0072422 signal transduction involved in DNA damage checkpoint 1.72123823174599e-05 75 48 5 0.104166666666667 0.0666666666666667
GO:BP GO:0072401 signal transduction involved in DNA integrity checkpoint 1.72123823174599e-05 75 48 5 0.104166666666667 0.0666666666666667
GO:BP GO:0022412 cellular process involved in reproduction in multicellular organism 1.80151987370437e-05 366 42 8 0.19047619047619 0.0218579234972678
GO:BP GO:0071824 protein-DNA complex subunit organization 2.06170000800931e-05 294 111 11 0.0990990990990991 0.0374149659863946
GO:BP GO:0072395 signal transduction involved in cell cycle checkpoint 2.06196770085173e-05 78 48 5 0.104166666666667 0.0641025641025641
GO:BP GO:0051603 proteolysis involved in cellular protein catabolic process 2.49784291734432e-05 750 23 8 0.347826086956522 0.0106666666666667
GO:BP GO:0071900 regulation of protein serine/threonine kinase activity 2.88924814758492e-05 503 44 9 0.204545454545455 0.0178926441351889
GO:BP GO:0031396 regulation of protein ubiquitination 2.90126302949057e-05 211 20 5 0.25 0.023696682464455
GO:BP GO:0045737 positive regulation of cyclin-dependent protein serine/threonine kinase activity 3.09601932603631e-05 29 18 3 0.166666666666667 0.103448275862069
GO:BP GO:0035404 histone-serine phosphorylation 3.09601932603631e-05 10 54 3 0.0555555555555556 0.3
GO:BP GO:0006998 nuclear envelope organization 3.4283132643759e-05 55 34 4 0.117647058823529 0.0727272727272727
GO:BP GO:0065004 protein-DNA complex assembly 3.53547000637662e-05 252 111 10 0.0900900900900901 0.0396825396825397
GO:BP GO:0030010 establishment of cell polarity 3.75272162310399e-05 142 116 8 0.0689655172413793 0.0563380281690141
GO:BP GO:0045860 positive regulation of protein kinase activity 3.81950456522387e-05 534 94 13 0.138297872340426 0.0243445692883895
GO:BP GO:0010032 meiotic chromosome condensation 4.02337880157712e-05 6 107 3 0.0280373831775701 0.5
GO:BP GO:0019222 regulation of metabolic process 4.02337880157712e-05 7148 20 18 0.9 0.00251818690542809
GO:BP GO:0010638 positive regulation of organelle organization 4.06911607280683e-05 603 125 16 0.128 0.0265339966832504
GO:BP GO:0006997 nucleus organization 4.17498246659084e-05 130 34 5 0.147058823529412 0.0384615384615385
GO:BP GO:0044257 cellular protein catabolic process 4.27848744643258e-05 813 23 8 0.347826086956522 0.00984009840098401
GO:BP GO:0006325 chromatin organization 4.27848744643258e-05 824 115 18 0.156521739130435 0.0218446601941748
GO:BP GO:1904031 positive regulation of cyclin-dependent protein kinase activity 4.379750659521e-05 33 18 3 0.166666666666667 0.0909090909090909
GO:BP GO:0031570 DNA integrity checkpoint 4.44706512298905e-05 164 48 6 0.125 0.0365853658536585
GO:BP GO:0043549 regulation of kinase activity 4.48780308120034e-05 921 94 17 0.180851063829787 0.0184581976112921
GO:BP GO:0031110 regulation of microtubule polymerization or depolymerization 4.50756298039469e-05 85 92 6 0.0652173913043478 0.0705882352941176
GO:BP GO:0045143 homologous chromosome segregation 4.53628265791283e-05 62 72 5 0.0694444444444444 0.0806451612903226
GO:BP GO:0007276 gamete generation 4.57369629537975e-05 708 121 17 0.140495867768595 0.0240112994350282
GO:BP GO:1903320 regulation of protein modification by small protein conjugation or removal 5.27302069408479e-05 243 20 5 0.25 0.0205761316872428
GO:BP GO:0008104 protein localization 5.33937458411563e-05 2770 125 39 0.312 0.0140794223826715
GO:BP GO:1901989 positive regulation of cell cycle phase transition 5.43474751950557e-05 109 114 7 0.0614035087719298 0.0642201834862385
GO:BP GO:0031401 positive regulation of protein modification process 5.92695618216746e-05 1074 19 8 0.421052631578947 0.0074487895716946
GO:BP GO:0031398 positive regulation of protein ubiquitination 6.21281116450684e-05 120 19 4 0.210526315789474 0.0333333333333333
GO:BP GO:0019882 antigen processing and presentation 6.90993396509308e-05 234 130 10 0.0769230769230769 0.0427350427350427
GO:BP GO:0006468 protein phosphorylation 6.92040281896348e-05 1668 62 18 0.290322580645161 0.0107913669064748
GO:BP GO:0019953 sexual reproduction 7.08537527420826e-05 867 125 19 0.152 0.0219146482122261
GO:BP GO:0009057 macromolecule catabolic process 7.49378095361564e-05 1468 24 10 0.416666666666667 0.00681198910081744
GO:BP GO:0022411 cellular component disassembly 7.54986554264718e-05 571 34 8 0.235294117647059 0.0140105078809107
GO:BP GO:0051704 multi-organism process 8.03269363760396e-05 1135 65 15 0.230769230769231 0.013215859030837
GO:BP GO:0070601 centromeric sister chromatid cohesion 8.83308213454186e-05 11 72 3 0.0416666666666667 0.272727272727273
GO:BP GO:0006259 DNA metabolic process 8.83308213454186e-05 965 125 20 0.16 0.0207253886010363
GO:BP GO:0044265 cellular macromolecule catabolic process 9.24875285356628e-05 1231 23 9 0.391304347826087 0.00731112916328188
GO:BP GO:0007144 female meiosis I 9.98397416761046e-05 9 94 3 0.0319148936170213 0.333333333333333
GO:BP GO:0031503 protein-containing complex localization 0.000100318665405241 289 88 9 0.102272727272727 0.0311418685121107
GO:BP GO:0044774 mitotic DNA integrity checkpoint 0.000101921523117173 112 48 5 0.104166666666667 0.0446428571428571
GO:BP GO:1904776 regulation of protein localization to cell cortex 0.000105065574771423 9 96 3 0.03125 0.333333333333333
GO:BP GO:1903322 positive regulation of protein modification by small protein conjugation or removal 0.000106968995901187 140 19 4 0.210526315789474 0.0285714285714286
GO:BP GO:0051445 regulation of meiotic cell cycle 0.000109742215518852 48 114 5 0.043859649122807 0.104166666666667
GO:BP GO:1900182 positive regulation of protein localization to nucleus 0.000113312784398412 90 61 5 0.0819672131147541 0.0555555555555556
GO:BP GO:0007019 microtubule depolymerization 0.000117632785375715 46 121 5 0.0413223140495868 0.108695652173913
GO:BP GO:0044843 cell cycle G1/S phase transition 0.000125037479932307 309 85 9 0.105882352941176 0.029126213592233
GO:BP GO:0033674 positive regulation of kinase activity 0.000129854031305028 608 94 13 0.138297872340426 0.0213815789473684
GO:BP GO:0030163 protein catabolic process 0.000138562323522882 974 23 8 0.347826086956522 0.0082135523613963
GO:BP GO:0034728 nucleosome organization 0.000139299323311891 182 111 8 0.0720720720720721 0.043956043956044
GO:BP GO:0006977 DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest 0.000141284127971013 58 48 4 0.0833333333333333 0.0689655172413793
GO:BP GO:1902400 intracellular signal transduction involved in G1 DNA damage checkpoint 0.000150088220736757 59 48 4 0.0833333333333333 0.0677966101694915
GO:BP GO:0072431 signal transduction involved in mitotic G1 DNA damage checkpoint 0.000150088220736757 59 48 4 0.0833333333333333 0.0677966101694915
GO:BP GO:0072698 protein localization to microtubule cytoskeleton 0.000151552936360162 54 109 5 0.0458715596330275 0.0925925925925926
GO:BP GO:0034622 cellular protein-containing complex assembly 0.000158315567621439 1107 40 11 0.275 0.00993676603432701
GO:BP GO:0034613 cellular protein localization 0.000163489778144977 2014 66 20 0.303030303030303 0.0099304865938431
GO:BP GO:1901993 regulation of meiotic cell cycle phase transition 0.000165240667379732 9 114 3 0.0263157894736842 0.333333333333333
GO:BP GO:1902403 signal transduction involved in mitotic DNA integrity checkpoint 0.000167515883294147 61 48 4 0.0833333333333333 0.0655737704918033
GO:BP GO:1902402 signal transduction involved in mitotic DNA damage checkpoint 0.000167515883294147 61 48 4 0.0833333333333333 0.0655737704918033
GO:BP GO:0070727 cellular macromolecule localization 0.000172535009411082 2024 66 20 0.303030303030303 0.00988142292490119
GO:BP GO:1902750 negative regulation of cell cycle G2/M phase transition 0.000174369051434788 113 54 5 0.0925925925925926 0.0442477876106195
GO:BP GO:0007050 cell cycle arrest 0.000175728445030282 241 114 9 0.0789473684210526 0.037344398340249
GO:BP GO:0072697 protein localization to cell cortex 0.000185832231181001 11 96 3 0.03125 0.272727272727273
GO:BP GO:0072413 signal transduction involved in mitotic cell cycle checkpoint 0.000185832231181001 63 48 4 0.0833333333333333 0.0634920634920635
GO:BP GO:0010971 positive regulation of G2/M transition of mitotic cell cycle 0.000187295744521395 27 114 4 0.0350877192982456 0.148148148148148
GO:BP GO:1901992 positive regulation of mitotic cell cycle phase transition 0.00018760511435398 91 114 6 0.0526315789473684 0.0659340659340659
GO:BP GO:0048522 positive regulation of cellular process 0.0001914619932427 5757 98 51 0.520408163265306 0.0088587806149036
GO:BP GO:0044380 protein localization to cytoskeleton 0.000202849979325592 58 109 5 0.0458715596330275 0.0862068965517241
GO:BP GO:0001934 positive regulation of protein phosphorylation 0.000207147864440259 840 94 15 0.159574468085106 0.0178571428571429
GO:BP GO:0006334 nucleosome assembly 0.000211850523866713 142 111 7 0.0630630630630631 0.0492957746478873
GO:BP GO:0031571 mitotic G1 DNA damage checkpoint 0.000216754809860967 66 48 4 0.0833333333333333 0.0606060606060606
GO:BP GO:0042770 signal transduction in response to DNA damage 0.000220113990091522 135 48 5 0.104166666666667 0.037037037037037
GO:BP GO:0044783 G1 DNA damage checkpoint 0.000226806656125404 67 48 4 0.0833333333333333 0.0597014925373134
GO:BP GO:0044819 mitotic G1/S transition checkpoint 0.000226806656125404 67 48 4 0.0833333333333333 0.0597014925373134
GO:BP GO:0070979 protein K11-linked ubiquitination 0.000232203564655644 29 113 4 0.0353982300884956 0.137931034482759
GO:BP GO:1901565 organonitrogen compound catabolic process 0.000258182802467165 1358 24 9 0.375 0.00662739322533137
GO:BP GO:1902751 positive regulation of cell cycle G2/M phase transition 0.000273125974855238 30 114 4 0.0350877192982456 0.133333333333333
GO:BP GO:0042325 regulation of phosphorylation 0.000277893880120747 1431 94 20 0.212765957446809 0.0139762403913347
GO:BP GO:0006508 proteolysis 0.000278470071974528 1836 23 10 0.434782608695652 0.00544662309368192
GO:BP GO:0051179 localization 0.000287562795563743 6901 69 43 0.623188405797101 0.00623098101724388
GO:BP GO:0065003 protein-containing complex assembly 0.000294927343067196 1680 40 13 0.325 0.00773809523809524
GO:BP GO:0048609 multicellular organismal reproductive process 0.000301194828558 845 65 12 0.184615384615385 0.0142011834319527
GO:BP GO:0032270 positive regulation of cellular protein metabolic process 0.000329691225099806 1477 23 9 0.391304347826087 0.00609343263371699
GO:BP GO:0090231 regulation of spindle checkpoint 0.000332457526592047 15 86 3 0.0348837209302326 0.2
GO:BP GO:1903504 regulation of mitotic spindle checkpoint 0.000332457526592047 15 86 3 0.0348837209302326 0.2
GO:BP GO:0090266 regulation of mitotic cell cycle spindle assembly checkpoint 0.000332457526592047 15 86 3 0.0348837209302326 0.2
GO:BP GO:0046785 microtubule polymerization 0.000335269162860044 79 90 5 0.0555555555555556 0.0632911392405063
GO:BP GO:0032504 multicellular organism reproduction 0.000370291107292857 865 65 12 0.184615384615385 0.0138728323699422
GO:BP GO:0033365 protein localization to organelle 0.000379246487315046 1017 133 20 0.150375939849624 0.0196656833824975
GO:BP GO:0006974 cellular response to DNA damage stimulus 0.000381474549024177 888 128 18 0.140625 0.0202702702702703
GO:BP GO:0000077 DNA damage checkpoint 0.000384418350813694 154 48 5 0.104166666666667 0.0324675324675325
GO:BP GO:0006338 chromatin remodeling 0.000386647524301872 215 111 8 0.0720720720720721 0.0372093023255814
GO:BP GO:0006913 nucleocytoplasmic transport 0.000396102881522923 354 88 9 0.102272727272727 0.0254237288135593
GO:BP GO:0050658 RNA transport 0.000396102881522923 201 88 7 0.0795454545454545 0.0348258706467662
GO:BP GO:0050657 nucleic acid transport 0.000396102881522923 201 88 7 0.0795454545454545 0.0348258706467662
GO:BP GO:0051493 regulation of cytoskeleton organization 0.000396243423104065 531 121 13 0.107438016528926 0.0244821092278719
GO:BP GO:0044260 cellular macromolecule metabolic process 0.000404414869013246 8390 20 18 0.9 0.00214541120381406
GO:BP GO:0051169 nuclear transport 0.000415418418464144 357 88 9 0.102272727272727 0.0252100840336134
GO:BP GO:0001932 regulation of protein phosphorylation 0.000417659460348037 1240 94 18 0.191489361702128 0.0145161290322581
GO:BP GO:0016310 phosphorylation 0.000423620051746186 2138 62 19 0.306451612903226 0.00888681010289991
GO:BP GO:0051236 establishment of RNA localization 0.000425159357710639 204 88 7 0.0795454545454545 0.0343137254901961
GO:BP GO:0051258 protein polymerization 0.00044884213615484 305 26 5 0.192307692307692 0.0163934426229508
GO:BP GO:0007100 mitotic centrosome separation 0.000469857130113976 14 106 3 0.0283018867924528 0.214285714285714
GO:BP GO:0044703 multi-organism reproductive process 0.000476376034788903 1040 65 13 0.2 0.0125
GO:BP GO:0051247 positive regulation of protein metabolic process 0.000480168195856664 1564 23 9 0.391304347826087 0.00575447570332481
GO:BP GO:0030866 cortical actin cytoskeleton organization 0.000481225644257974 41 98 4 0.0408163265306122 0.0975609756097561
GO:BP GO:0033036 macromolecule localization 0.000539963980657465 3218 125 40 0.32 0.0124300807955252
GO:BP GO:0042327 positive regulation of phosphorylation 0.000549533715221359 927 94 15 0.159574468085106 0.0161812297734628
GO:BP GO:0046824 positive regulation of nucleocytoplasmic transport 0.000549533715221359 68 61 4 0.0655737704918033 0.0588235294117647
GO:BP GO:0051299 centrosome separation 0.000570248347775709 15 106 3 0.0283018867924528 0.2
GO:BP GO:0071158 positive regulation of cell cycle arrest 0.000580180510688204 88 48 4 0.0833333333333333 0.0454545454545455
GO:BP GO:0010457 centriole-centriole cohesion 0.000656557790277135 14 120 3 0.025 0.214285714285714
GO:BP GO:0045840 positive regulation of mitotic nuclear division 0.000661494745938448 43 38 3 0.0789473684210526 0.0697674418604651
GO:BP GO:0007063 regulation of sister chromatid cohesion 0.000684042621937982 22 76 3 0.0394736842105263 0.136363636363636
GO:BP GO:1900180 regulation of protein localization to nucleus 0.00068891270826368 139 61 5 0.0819672131147541 0.0359712230215827
GO:BP GO:0045931 positive regulation of mitotic cell cycle 0.00069805085327223 119 114 6 0.0526315789473684 0.0504201680672269
GO:BP GO:0006310 DNA recombination 0.000852404916531211 294 118 9 0.076271186440678 0.0306122448979592
GO:BP GO:0060271 cilium assembly 0.000852404916531211 395 130 11 0.0846153846153846 0.0278481012658228
GO:BP GO:0048518 positive regulation of biological process 0.000863612376395926 6363 70 40 0.571428571428571 0.00628634292000629
GO:BP GO:0051173 positive regulation of nitrogen compound metabolic process 0.000865805065006846 3083 40 17 0.425 0.00551410963347389
GO:BP GO:0072331 signal transduction by p53 class mediator 0.00090528704950091 268 54 6 0.111111111111111 0.0223880597014925
GO:BP GO:0006403 RNA localization 0.00101400528939201 238 88 7 0.0795454545454545 0.0294117647058824
GO:BP GO:0044267 cellular protein metabolic process 0.00104237374277596 5229 20 14 0.7 0.00267737617135207
GO:BP GO:0007064 mitotic sister chromatid cohesion 0.00104237374277596 27 72 3 0.0416666666666667 0.111111111111111
GO:BP GO:2001252 positive regulation of chromosome organization 0.00104810163943478 168 125 7 0.056 0.0416666666666667
GO:BP GO:0051098 regulation of binding 0.00111079889339002 365 59 7 0.11864406779661 0.0191780821917808
GO:BP GO:0044773 mitotic DNA damage checkpoint 0.00111079889339002 106 48 4 0.0833333333333333 0.0377358490566038
GO:BP GO:0010562 positive regulation of phosphorus metabolic process 0.00117459644613068 1001 94 15 0.159574468085106 0.014985014985015
GO:BP GO:0045937 positive regulation of phosphate metabolic process 0.00117459644613068 1001 94 15 0.159574468085106 0.014985014985015
GO:BP GO:1902410 mitotic cytokinetic process 0.00117459644613068 23 89 3 0.0337078651685393 0.130434782608696
GO:BP GO:0031497 chromatin assembly 0.00119239634436464 194 111 7 0.0630630630630631 0.0360824742268041
GO:BP GO:0043933 protein-containing complex subunit organization 0.00120710514231716 1963 40 13 0.325 0.00662251655629139
GO:BP GO:0032436 positive regulation of proteasomal ubiquitin-dependent protein catabolic process 0.00120710514231716 90 23 3 0.130434782608696 0.0333333333333333
GO:BP GO:0030705 cytoskeleton-dependent intracellular transport 0.00124892462241864 202 76 6 0.0789473684210526 0.0297029702970297
GO:BP GO:0030330 DNA damage response, signal transduction by p53 class mediator 0.00124892462241864 110 48 4 0.0833333333333333 0.0363636363636364
GO:BP GO:0044782 cilium organization 0.00128289703894101 417 130 11 0.0846153846153846 0.026378896882494
GO:BP GO:0051785 positive regulation of nuclear division 0.00139955365150685 57 38 3 0.0789473684210526 0.0526315789473684
GO:BP GO:0071156 regulation of cell cycle arrest 0.00145601191896105 115 48 4 0.0833333333333333 0.0347826086956522
GO:BP GO:0010972 negative regulation of G2/M transition of mitotic cell cycle 0.00145601191896105 102 54 4 0.0740740740740741 0.0392156862745098
GO:BP GO:0019220 regulation of phosphate metabolic process 0.00149285417197465 1645 94 20 0.212765957446809 0.0121580547112462
GO:BP GO:0051174 regulation of phosphorus metabolic process 0.00149285417197465 1645 94 20 0.212765957446809 0.0121580547112462
GO:BP GO:0001556 oocyte maturation 0.00151155670923735 24 94 3 0.0319148936170213 0.125
GO:BP GO:0015931 nucleobase-containing compound transport 0.00162665363521257 260 88 7 0.0795454545454545 0.0269230769230769
GO:BP GO:0030162 regulation of proteolysis 0.00163115474056436 752 23 6 0.260869565217391 0.00797872340425532
GO:BP GO:0006611 protein export from nucleus 0.00166884036036751 185 88 6 0.0681818181818182 0.0324324324324324
GO:BP GO:0031325 positive regulation of cellular metabolic process 0.00168307598610603 3274 40 17 0.425 0.00519242516799023
GO:BP GO:0036211 protein modification process 0.00177255837781 4041 20 12 0.6 0.00296956198960653
GO:BP GO:0006464 cellular protein modification process 0.00177255837781 4041 20 12 0.6 0.00296956198960653
GO:BP GO:0050794 regulation of cellular process 0.00178856727709077 11473 66 55 0.833333333333333 0.00479386385426654
GO:BP GO:0032434 regulation of proteasomal ubiquitin-dependent protein catabolic process 0.00179592866654954 134 44 4 0.0909090909090909 0.0298507462686567
GO:BP GO:0007020 microtubule nucleation 0.00179812269310615 32 75 3 0.04 0.09375
GO:BP GO:2000060 positive regulation of ubiquitin-dependent protein catabolic process 0.00188272598602816 107 23 3 0.130434782608696 0.0280373831775701
GO:BP GO:1902806 regulation of cell cycle G1/S phase transition 0.00188577322490939 206 114 7 0.0614035087719298 0.0339805825242718
GO:BP GO:1901575 organic substance catabolic process 0.00196188814207336 2267 24 10 0.416666666666667 0.00441111601235112
GO:BP GO:2000134 negative regulation of G1/S transition of mitotic cell cycle 0.0020704762146639 128 48 4 0.0833333333333333 0.03125
GO:BP GO:0000082 G1/S transition of mitotic cell cycle 0.00208909352353318 283 85 7 0.0823529411764706 0.0247349823321555
GO:BP GO:0007281 germ cell development 0.00210162957087634 268 42 5 0.119047619047619 0.0186567164179104
GO:BP GO:1901800 positive regulation of proteasomal protein catabolic process 0.00210267602326202 112 23 3 0.130434782608696 0.0267857142857143
GO:BP GO:0030865 cortical cytoskeleton organization 0.00211577839243601 63 98 4 0.0408163265306122 0.0634920634920635
GO:BP GO:0042307 positive regulation of protein import into nucleus 0.00213404728167064 42 61 3 0.0491803278688525 0.0714285714285714
GO:BP GO:0090316 positive regulation of intracellular protein transport 0.00223978381707385 186 61 5 0.0819672131147541 0.0268817204301075
GO:BP GO:0006333 chromatin assembly or disassembly 0.00223978381707385 219 111 7 0.0630630630630631 0.0319634703196347
GO:BP GO:0031100 animal organ regeneration 0.00223978381707385 77 34 3 0.0882352941176471 0.038961038961039
GO:BP GO:0034504 protein localization to nucleus 0.00230248143597207 289 61 6 0.0983606557377049 0.0207612456747405
GO:BP GO:0051972 regulation of telomerase activity 0.0023184998715909 51 125 4 0.032 0.0784313725490196
GO:BP GO:0048477 oogenesis 0.00232740494492552 89 30 3 0.1 0.0337078651685393
GO:BP GO:0071426 ribonucleoprotein complex export from nucleus 0.00235320082191601 130 88 5 0.0568181818181818 0.0384615384615385
GO:BP GO:1902807 negative regulation of cell cycle G1/S phase transition 0.00237031585827181 134 48 4 0.0833333333333333 0.0298507462686567
GO:BP GO:1904591 positive regulation of protein import 0.00237836555991255 44 61 3 0.0491803278688525 0.0681818181818182
GO:BP GO:0048193 Golgi vesicle transport 0.00237836555991255 382 130 10 0.0769230769230769 0.0261780104712042
GO:BP GO:0071166 ribonucleoprotein complex localization 0.00241294622360463 131 88 5 0.0568181818181818 0.0381679389312977
GO:BP GO:0008284 positive regulation of cell population proliferation 0.00247940479798331 982 35 8 0.228571428571429 0.00814663951120163
GO:BP GO:0051168 nuclear export 0.00255368309923894 204 88 6 0.0681818181818182 0.0294117647058824
GO:BP GO:0090169 regulation of spindle assembly 0.0026611634152638 26 109 3 0.0275229357798165 0.115384615384615
GO:BP GO:1901976 regulation of cell cycle checkpoint 0.00269012413920483 33 86 3 0.0348837209302326 0.0909090909090909
GO:BP GO:0060341 regulation of cellular localization 0.00269012413920483 851 61 10 0.163934426229508 0.0117508813160987
GO:BP GO:0043412 macromolecule modification 0.00269012413920483 4257 20 12 0.6 0.00281888653981677
GO:BP GO:0007283 spermatogenesis 0.00275486014258201 551 6 3 0.5 0.00544464609800363
GO:BP GO:0032210 regulation of telomere maintenance via telomerase 0.00275486014258201 54 125 4 0.032 0.0740740740740741
GO:BP GO:1903829 positive regulation of cellular protein localization 0.00280619452383355 303 61 6 0.0983606557377049 0.0198019801980198
GO:BP GO:0019538 protein metabolic process 0.00292479002745277 5808 20 14 0.7 0.00241046831955923
GO:BP GO:0031099 regeneration 0.00299585657054507 206 34 4 0.117647058823529 0.0194174757281553
GO:BP GO:0048232 male gamete generation 0.00299585657054507 570 6 3 0.5 0.00526315789473684
GO:BP GO:1903052 positive regulation of proteolysis involved in cellular protein catabolic process 0.00304809445858742 131 23 3 0.130434782608696 0.0229007633587786
GO:BP GO:0046822 regulation of nucleocytoplasmic transport 0.00313541414459901 115 61 4 0.0655737704918033 0.0347826086956522
GO:BP GO:0044248 cellular catabolic process 0.00313541414459901 2347 7 5 0.714285714285714 0.00213037920749893
GO:BP GO:0010604 positive regulation of macromolecule metabolic process 0.00313778380786218 3483 40 17 0.425 0.00488084984209015
GO:BP GO:2000241 regulation of reproductive process 0.00316140631978831 165 114 6 0.0526315789473684 0.0363636363636364
GO:BP GO:0008283 cell population proliferation 0.00320056253532078 2054 70 18 0.257142857142857 0.00876338851022395
GO:BP GO:0006405 RNA export from nucleus 0.00336969416668928 143 88 5 0.0568181818181818 0.034965034965035
GO:BP GO:2000058 regulation of ubiquitin-dependent protein catabolic process 0.00343741811530739 165 44 4 0.0909090909090909 0.0242424242424242
GO:BP GO:0018105 peptidyl-serine phosphorylation 0.00348503555541376 313 62 6 0.0967741935483871 0.0191693290734824
GO:BP GO:0006915 apoptotic process 0.00348503555541376 1990 61 16 0.262295081967213 0.00804020100502513
GO:BP GO:0043170 macromolecule metabolic process 0.00353507901316926 9796 20 18 0.9 0.0018374846876276
GO:BP GO:1902117 positive regulation of organelle assembly 0.00376324528010023 68 109 4 0.036697247706422 0.0588235294117647
GO:BP GO:0043066 negative regulation of apoptotic process 0.00406474601640453 921 23 6 0.260869565217391 0.00651465798045603
GO:BP GO:0051222 positive regulation of protein transport 0.00409778755806531 329 61 6 0.0983606557377049 0.0182370820668693
GO:BP GO:0032269 negative regulation of cellular protein metabolic process 0.00416987697467428 1082 20 6 0.3 0.0055452865064695
GO:BP GO:0043069 negative regulation of programmed cell death 0.00455858892050012 943 23 6 0.260869565217391 0.0063626723223754
GO:BP GO:1903364 positive regulation of cellular protein catabolic process 0.0046328266979027 154 23 3 0.130434782608696 0.0194805194805195
GO:BP GO:0051130 positive regulation of cellular component organization 0.0046328266979027 1153 125 18 0.144 0.01561144839549
GO:BP GO:1904356 regulation of telomere maintenance via telomere lengthening 0.0046328266979027 63 125 4 0.032 0.0634920634920635
GO:BP GO:0071902 positive regulation of protein serine/threonine kinase activity 0.00477535519244068 316 44 5 0.113636363636364 0.0158227848101266
GO:BP GO:0018209 peptidyl-serine modification 0.00486815197767807 336 62 6 0.0967741935483871 0.0178571428571429
GO:BP GO:0051234 establishment of localization 0.00486815197767807 5372 90 41 0.455555555555556 0.00763216679076694
GO:BP GO:0044092 negative regulation of molecular function 0.00489186315194187 1219 32 8 0.25 0.00656275635767022
GO:BP GO:2000045 regulation of G1/S transition of mitotic cell cycle 0.00498796928211253 182 114 6 0.0526315789473684 0.032967032967033
GO:BP GO:0032388 positive regulation of intracellular transport 0.00499430546605535 229 61 5 0.0819672131147541 0.0218340611353712
GO:BP GO:1904951 positive regulation of establishment of protein localization 0.00506396330711346 345 61 6 0.0983606557377049 0.0173913043478261
GO:BP GO:0061136 regulation of proteasomal protein catabolic process 0.00509840300730173 186 44 4 0.0909090909090909 0.021505376344086
GO:BP GO:0010951 negative regulation of endopeptidase activity 0.00519220247776685 253 15 3 0.2 0.0118577075098814
GO:BP GO:0006807 nitrogen compound metabolic process 0.00526585636102553 10078 20 18 0.9 0.00178606866441754
GO:BP GO:0048523 negative regulation of cellular process 0.00528801955106608 5139 35 19 0.542857142857143 0.00369721735746254
GO:BP GO:0051261 protein depolymerization 0.00536378778181828 117 121 5 0.0413223140495868 0.0427350427350427
GO:BP GO:0051248 negative regulation of protein metabolic process 0.00546758932215749 1151 20 6 0.3 0.0052128583840139
GO:BP GO:0120031 plasma membrane bounded cell projection assembly 0.00547086821385678 593 130 12 0.0923076923076923 0.0202360876897133
GO:BP GO:0042306 regulation of protein import into nucleus 0.00557800209562228 62 61 3 0.0491803278688525 0.0483870967741935
GO:BP GO:0032392 DNA geometric change 0.00565404024947266 116 33 3 0.0909090909090909 0.0258620689655172
GO:BP GO:0010466 negative regulation of peptidase activity 0.00586973427148932 267 15 3 0.2 0.0112359550561798
GO:BP GO:0009056 catabolic process 0.00591435793140511 2744 7 5 0.714285714285714 0.00182215743440233
GO:BP GO:0007004 telomere maintenance via telomerase 0.00609855386220993 69 125 4 0.032 0.0579710144927536
GO:BP GO:0006281 DNA repair 0.00623293564305021 576 118 11 0.0932203389830508 0.0190972222222222
GO:BP GO:1904589 regulation of protein import 0.0062881306723058 65 61 3 0.0491803278688525 0.0461538461538462
GO:BP GO:0010256 endomembrane system organization 0.00646298369815832 484 19 4 0.210526315789474 0.00826446280991736
GO:BP GO:0030031 cell projection assembly 0.00646298369815832 607 130 12 0.0923076923076923 0.0197693574958814
GO:BP GO:0006278 RNA-dependent DNA biosynthetic process 0.00666888127965187 71 125 4 0.032 0.0563380281690141
GO:BP GO:1903793 positive regulation of anion transport 0.00667426963254277 504 61 7 0.114754098360656 0.0138888888888889
GO:BP GO:0042176 regulation of protein catabolic process 0.00676003759400785 401 23 4 0.173913043478261 0.00997506234413965
GO:BP GO:0045995 regulation of embryonic development 0.00676003759400785 63 65 3 0.0461538461538462 0.0476190476190476
GO:BP GO:0060548 negative regulation of cell death 0.00680776006905985 1038 23 6 0.260869565217391 0.00578034682080925
GO:BP GO:0012501 programmed cell death 0.00690190301542459 2143 61 16 0.262295081967213 0.00746616892207186
GO:BP GO:0009893 positive regulation of metabolic process 0.00723794734430866 3783 40 17 0.425 0.00449378799894264
GO:BP GO:0051973 positive regulation of telomerase activity 0.00731489325540372 34 125 3 0.024 0.0882352941176471
GO:BP GO:0032212 positive regulation of telomere maintenance via telomerase 0.00731489325540372 34 125 3 0.024 0.0882352941176471
GO:BP GO:0006606 protein import into nucleus 0.00759549777529059 152 61 4 0.0655737704918033 0.0263157894736842
GO:BP GO:0007264 small GTPase mediated signal transduction 0.0077610013029802 515 97 9 0.0927835051546392 0.0174757281553398
GO:BP GO:1902115 regulation of organelle assembly 0.0077610013029802 192 120 6 0.05 0.03125
GO:BP GO:0031124 mRNA 3'-end processing 0.00776516362913264 106 88 4 0.0454545454545455 0.0377358490566038
GO:BP GO:0075733 intracellular transport of virus 0.00828378093112633 57 78 3 0.0384615384615385 0.0526315789473684
GO:BP GO:0033157 regulation of intracellular protein transport 0.00841789504221637 264 61 5 0.0819672131147541 0.0189393939393939
GO:BP GO:0043086 negative regulation of catalytic activity 0.00843140257712217 851 20 5 0.25 0.00587544065804935
GO:BP GO:1903050 regulation of proteolysis involved in cellular protein catabolic process 0.00858060990822964 221 44 4 0.0909090909090909 0.0180995475113122
GO:BP GO:0050789 regulation of biological process 0.00872268643557743 12091 66 55 0.833333333333333 0.00454883797866181
GO:BP GO:1904358 positive regulation of telomere maintenance via telomere lengthening 0.0089702650632347 37 125 3 0.024 0.0810810810810811
GO:BP GO:0071427 mRNA-containing ribonucleoprotein complex export from nucleus 0.00920005496565876 112 88 4 0.0454545454545455 0.0357142857142857
GO:BP GO:0006406 mRNA export from nucleus 0.00920005496565876 112 88 4 0.0454545454545455 0.0357142857142857
GO:BP GO:0001578 microtubule bundle formation 0.00959107781763704 111 90 4 0.0444444444444444 0.036036036036036
GO:BP GO:0031113 regulation of microtubule polymerization 0.00976381639762714 53 90 3 0.0333333333333333 0.0566037735849057
GO:BP GO:0042981 regulation of apoptotic process 0.00996447495591715 1549 23 7 0.304347826086957 0.00451904454486766
GO:BP GO:0044238 primary metabolic process 0.00997437538844687 10584 20 18 0.9 0.00170068027210884
GO:BP GO:0016567 protein ubiquitination 0.00999024681546776 892 20 5 0.25 0.00560538116591928
GO:BP GO:0010833 telomere maintenance via telomere lengthening 0.010275580875521 82 125 4 0.032 0.0487804878048781
GO:BP GO:0008219 cell death 0.010275580875521 2292 25 9 0.36 0.00392670157068063
GO:BP GO:0006796 phosphate-containing compound metabolic process 0.010275580875521 3087 62 20 0.32258064516129 0.00647878198898607
GO:BP GO:0032204 regulation of telomere maintenance 0.010275580875521 82 125 4 0.032 0.0487804878048781
GO:BP GO:0046794 transport of virus 0.0108481899399673 64 78 3 0.0384615384615385 0.046875
GO:BP GO:0043067 regulation of programmed cell death 0.0109489357107184 1582 23 7 0.304347826086957 0.00442477876106195
GO:BP GO:0051170 import into nucleus 0.0109648834472945 172 61 4 0.0655737704918033 0.0232558139534884
GO:BP GO:0006793 phosphorus metabolic process 0.011228267176369 3114 62 20 0.32258064516129 0.00642260757867694
GO:BP GO:0016570 histone modification 0.0113343883376981 464 115 9 0.0782608695652174 0.0193965517241379
GO:BP GO:0003006 developmental process involved in reproduction 0.0113343883376981 982 6 3 0.5 0.00305498981670061
GO:BP GO:1902579 multi-organism localization 0.0115585845373608 66 78 3 0.0384615384615385 0.0454545454545455
GO:BP GO:0044766 multi-organism transport 0.0115585845373608 66 78 3 0.0384615384615385 0.0454545454545455
GO:BP GO:0045861 negative regulation of proteolysis 0.0117369990988432 359 15 3 0.2 0.00835654596100279
GO:BP GO:1903827 regulation of cellular protein localization 0.0118650789778322 572 61 7 0.114754098360656 0.0122377622377622
GO:BP GO:0046907 intracellular transport 0.012308682634599 1767 78 16 0.205128205128205 0.00905489530277306
GO:BP GO:0045732 positive regulation of protein catabolic process 0.0125978849218042 237 23 3 0.130434782608696 0.0126582278481013
GO:BP GO:1901564 organonitrogen compound metabolic process 0.0125978849218042 6792 20 14 0.7 0.00206124852767962
GO:BP GO:0070647 protein modification by small protein conjugation or removal 0.0126393368791894 1184 39 8 0.205128205128205 0.00675675675675676
GO:BP GO:0016569 covalent chromatin modification 0.0131324234983328 478 115 9 0.0782608695652174 0.0188284518828452
GO:BP GO:0032880 regulation of protein localization 0.0131324234983328 922 96 12 0.125 0.0130151843817787
GO:BP GO:0051223 regulation of protein transport 0.0131496308968506 586 61 7 0.114754098360656 0.0119453924914676
GO:BP GO:1903362 regulation of cellular protein catabolic process 0.0131496308968506 257 44 4 0.0909090909090909 0.0155642023346304
GO:BP GO:0032446 protein modification by small protein conjugation 0.0132807157251003 973 20 5 0.25 0.00513874614594039
GO:BP GO:0000380 alternative mRNA splicing, via spliceosome 0.0135073694857024 89 127 4 0.031496062992126 0.0449438202247191
GO:BP GO:0044237 cellular metabolic process 0.0136458558424646 10871 20 18 0.9 0.00165578143685034
GO:BP GO:0051172 negative regulation of nitrogen compound metabolic process 0.0137513023106244 2518 20 8 0.4 0.00317712470214456
GO:BP GO:0009987 cellular process 0.0139780632516878 17171 104 104 1 0.00605672354551278
GO:BP GO:0043393 regulation of protein binding 0.0148924424452791 199 59 4 0.0677966101694915 0.0201005025125628
GO:BP GO:0045184 establishment of protein localization 0.0154866901614393 2035 89 19 0.213483146067416 0.00933660933660934
GO:BP GO:0010941 regulation of cell death 0.0158237612096457 1720 23 7 0.304347826086957 0.00406976744186047
GO:BP GO:0070201 regulation of establishment of protein localization 0.0158641589268091 611 61 7 0.114754098360656 0.0114566284779051
GO:BP GO:0032147 activation of protein kinase activity 0.0160537665342104 331 84 6 0.0714285714285714 0.0181268882175227
GO:BP GO:0031032 actomyosin structure organization 0.0165433532303227 199 98 5 0.0510204081632653 0.0251256281407035
GO:BP GO:0006886 intracellular protein transport 0.0166792787917023 1186 78 12 0.153846153846154 0.0101180438448567
GO:BP GO:0090087 regulation of peptide transport 0.0166792787917023 618 61 7 0.114754098360656 0.0113268608414239
GO:BP GO:0048519 negative regulation of biological process 0.0172156672851201 5757 35 19 0.542857142857143 0.0033003300330033
GO:BP GO:0010970 transport along microtubule 0.0180956025257574 164 76 4 0.0526315789473684 0.024390243902439
GO:BP GO:0017038 protein import 0.0181176565435436 205 61 4 0.0655737704918033 0.0195121951219512
GO:BP GO:0052548 regulation of endopeptidase activity 0.0183872179336005 437 15 3 0.2 0.0068649885583524
GO:BP GO:0042127 regulation of cell population proliferation 0.0192942909073855 1774 35 9 0.257142857142857 0.00507328072153326
GO:BP GO:0032206 positive regulation of telomere maintenance 0.0195902903402858 52 125 3 0.024 0.0576923076923077
GO:BP GO:0031123 RNA 3'-end processing 0.0200864749728113 157 131 5 0.0381679389312977 0.0318471337579618
GO:BP GO:0031324 negative regulation of cellular metabolic process 0.0208092025737028 2719 20 8 0.4 0.00294225818315557
GO:BP GO:0052547 regulation of peptidase activity 0.0215610974944165 467 15 3 0.2 0.00642398286937901
GO:BP GO:0051346 negative regulation of hydrolase activity 0.0218416276106067 470 15 3 0.2 0.00638297872340425
GO:BP GO:0051028 mRNA transport 0.0223786512747716 152 88 4 0.0454545454545455 0.0263157894736842
GO:BP GO:0071704 organic substance metabolic process 0.0232554345783179 11326 20 18 0.9 0.00158926364117959
GO:BP GO:1902017 regulation of cilium assembly 0.0240204860866389 59 120 3 0.025 0.0508474576271186
GO:BP GO:0048469 cell maturation 0.0251668814908417 170 129 5 0.0387596899224806 0.0294117647058824
GO:BP GO:2000278 regulation of DNA biosynthetic process 0.025546359951634 112 125 4 0.032 0.0357142857142857
GO:BP GO:0032386 regulation of intracellular transport 0.0262481990468269 367 61 5 0.0819672131147541 0.0136239782016349
GO:BP GO:0018107 peptidyl-threonine phosphorylation 0.0269963154782118 120 62 3 0.0483870967741935 0.025
GO:BP GO:0051056 regulation of small GTPase mediated signal transduction 0.0278827056568998 328 97 6 0.0618556701030928 0.0182926829268293
GO:BP GO:0043270 positive regulation of ion transport 0.028272380581871 694 61 7 0.114754098360656 0.0100864553314121
GO:BP GO:0120036 plasma membrane bounded cell projection organization 0.0287266959308247 1569 42 9 0.214285714285714 0.00573613766730402
GO:BP GO:0065007 biological regulation 0.0295443785393486 12809 20 19 0.95 0.00148333203216488
GO:BP GO:0046777 protein autophosphorylation 0.0298863464622331 240 62 4 0.0645161290322581 0.0166666666666667
GO:BP GO:0006928 movement of cell or subcellular component 0.0308189837034777 2311 121 25 0.206611570247934 0.0108178277801817
GO:BP GO:0099111 microtubule-based transport 0.0309780396195895 198 76 4 0.0526315789473684 0.0202020202020202
GO:BP GO:0018210 peptidyl-threonine modification 0.0315186669359305 129 62 3 0.0483870967741935 0.0232558139534884
GO:BP GO:0044070 regulation of anion transport 0.0319715524837794 896 61 8 0.131147540983607 0.00892857142857143
GO:BP GO:0030030 cell projection organization 0.0323275893999123 1609 35 8 0.228571428571429 0.00497203231821007
GO:BP GO:0016032 viral process 0.0342180021914863 942 59 8 0.135593220338983 0.00849256900212314
GO:BP GO:2000573 positive regulation of DNA biosynthetic process 0.0345455698294018 67 125 3 0.024 0.0447761194029851
GO:BP GO:0051094 positive regulation of developmental process 0.0348381109546762 1341 7 3 0.428571428571429 0.00223713646532438
GO:BP GO:0071897 DNA biosynthetic process 0.0350228646092002 195 125 5 0.04 0.0256410256410256
GO:BP GO:0045862 positive regulation of proteolysis 0.0356643412545971 378 23 3 0.130434782608696 0.00793650793650794
GO:BP GO:0051100 negative regulation of binding 0.0379396719136584 163 54 3 0.0555555555555556 0.0184049079754601
GO:BP GO:0008152 metabolic process 0.0383779911271872 11827 20 18 0.9 0.00152194132070686
GO:BP GO:0031331 positive regulation of cellular catabolic process 0.0386265485196691 393 23 3 0.130434782608696 0.00763358778625954
GO:BP GO:0051052 regulation of DNA metabolic process 0.0386265485196691 363 125 7 0.056 0.0192837465564738
GO:BP GO:0061024 membrane organization 0.0389215846031106 973 37 6 0.162162162162162 0.00616649537512847
GO:BP GO:0009790 embryo development 0.0395199697915377 1035 35 6 0.171428571428571 0.00579710144927536
GO:BP GO:0010605 negative regulation of macromolecule metabolic process 0.0397092430680779 3241 23 9 0.391304347826087 0.00277692070348658
GO:BP GO:0044087 regulation of cellular component biogenesis 0.0406703023469787 990 120 13 0.108333333333333 0.0131313131313131
GO:BP GO:0043624 cellular protein complex disassembly 0.0414760659003299 226 75 4 0.0533333333333333 0.0176991150442478
GO:BP GO:2000243 positive regulation of reproductive process 0.0417449758733673 81 114 3 0.0263157894736842 0.037037037037037
GO:BP GO:0042752 regulation of circadian rhythm 0.042069359478493 122 76 3 0.0394736842105263 0.0245901639344262
GO:BP GO:0019219 regulation of nucleobase-containing compound metabolic process 0.0428566987080074 4091 19 9 0.473684210526316 0.00219995111219751
GO:BP GO:0044403 biological process involved in symbiotic interaction 0.0436191616751338 1001 59 8 0.135593220338983 0.00799200799200799
GO:BP GO:0006275 regulation of DNA replication 0.0436439914702602 111 85 3 0.0352941176470588 0.027027027027027
GO:BP GO:1901796 regulation of signal transduction by p53 class mediator 0.0464058475869725 180 54 3 0.0555555555555556 0.0166666666666667
GO:BP GO:0021987 cerebral cortex development 0.0474341947534076 118 83 3 0.036144578313253 0.0254237288135593
GO:BP GO:0016579 protein deubiquitination 0.0477682227032881 292 34 3 0.0882352941176471 0.0102739726027397
GO:CC GO:0005819 spindle 2.88601973552105e-52 387 133 53 0.398496240601504 0.136950904392765
GO:CC GO:0000775 chromosome, centromeric region 2.85799440924711e-50 204 133 43 0.323308270676692 0.21078431372549
GO:CC GO:0000779 condensed chromosome, centromeric region 1.5026090435576e-43 124 133 34 0.255639097744361 0.274193548387097
GO:CC GO:0098687 chromosomal region 1.29581519632031e-42 354 133 45 0.338345864661654 0.127118644067797
GO:CC GO:0000776 kinetochore 7.32359441737917e-42 139 133 34 0.255639097744361 0.244604316546763
GO:CC GO:0015630 microtubule cytoskeleton 1.09556133228461e-41 1307 133 68 0.511278195488722 0.0520275439938791
GO:CC GO:0000793 condensed chromosome 3.22632720100955e-41 217 133 38 0.285714285714286 0.175115207373272
GO:CC GO:0000777 condensed chromosome kinetochore 6.28657210297349e-37 108 133 29 0.218045112781955 0.268518518518519
GO:CC GO:0005874 microtubule 1.24150950556523e-33 434 132 41 0.310606060606061 0.0944700460829493
GO:CC GO:0099080 supramolecular complex 1.16614748467787e-32 1323 133 60 0.451127819548872 0.0453514739229025
GO:CC GO:0000922 spindle pole 3.20220790216144e-31 166 132 29 0.21969696969697 0.174698795180723
GO:CC GO:0072686 mitotic spindle 3.8751073819283e-30 159 133 28 0.210526315789474 0.176100628930818
GO:CC GO:0043232 intracellular non-membrane-bounded organelle 7.06754808883663e-29 5338 133 101 0.759398496240602 0.0189209441738479
GO:CC GO:0043228 non-membrane-bounded organelle 7.50493721986031e-29 5346 133 101 0.759398496240602 0.0188926300037411
GO:CC GO:0005856 cytoskeleton 3.37571148705232e-27 2332 133 69 0.518796992481203 0.0295883361921098
GO:CC GO:0030496 midbody 9.05078781219138e-25 196 132 26 0.196969696969697 0.13265306122449
GO:CC GO:0099513 polymeric cytoskeletal fiber 3.68842671941176e-24 764 132 41 0.310606060606061 0.0536649214659686
GO:CC GO:0005694 chromosome 1.40438636249956e-22 2071 136 61 0.448529411764706 0.0294543698696282
GO:CC GO:0005815 microtubule organizing center 3.73937553584266e-21 813 132 39 0.295454545454545 0.0479704797047971
GO:CC GO:0005813 centrosome 4.32318406147827e-20 619 132 34 0.257575757575758 0.0549273021001615
GO:CC GO:0099512 supramolecular fiber 5.836932845215e-20 993 132 41 0.310606060606061 0.0412890231621349
GO:CC GO:0099081 supramolecular polymer 7.49302492726721e-20 1001 132 41 0.310606060606061 0.040959040959041
GO:CC GO:0005634 nucleus 8.71211153190594e-20 7592 136 108 0.794117647058823 0.0142255005268704
GO:CC GO:0005829 cytosol 2.67157829013157e-18 5303 137 89 0.64963503649635 0.016782953045446
GO:CC GO:0005654 nucleoplasm 2.03578434480192e-16 4102 115 67 0.582608695652174 0.0163334958556802
GO:CC GO:0031981 nuclear lumen 2.36370780630095e-16 4444 136 78 0.573529411764706 0.0175517551755176
GO:CC GO:0005876 spindle microtubule 2.46425287182692e-16 72 121 14 0.115702479338843 0.194444444444444
GO:CC GO:0000940 condensed chromosome outer kinetochore 5.65721033106664e-14 14 116 8 0.0689655172413793 0.571428571428571
GO:CC GO:0051233 spindle midzone 2.07039417377017e-13 36 121 10 0.0826446280991736 0.277777777777778
GO:CC GO:0043229 intracellular organelle 2.3265234069588e-13 12491 136 127 0.933823529411765 0.0101673204707389
GO:CC GO:0070013 intracellular organelle lumen 4.90681042746344e-12 5402 115 70 0.608695652173913 0.0129581636430952
GO:CC GO:0005875 microtubule associated complex 5.1480127937589e-12 165 130 15 0.115384615384615 0.0909090909090909
GO:CC GO:0005622 intracellular anatomical structure 1.1460452114079e-11 14790 125 124 0.992 0.00838404327248141
GO:CC GO:0097431 mitotic spindle pole 1.37421713271423e-11 34 132 9 0.0681818181818182 0.264705882352941
GO:CC GO:0031974 membrane-enclosed lumen 2.01681705501041e-11 5565 115 70 0.608695652173913 0.0125786163522013
GO:CC GO:0043233 organelle lumen 2.01681705501041e-11 5565 115 70 0.608695652173913 0.0125786163522013
GO:CC GO:0005871 kinesin complex 3.63044204135716e-10 52 121 9 0.0743801652892562 0.173076923076923
GO:CC GO:0005737 cytoplasm 4.28722241600375e-10 11911 134 118 0.880597014925373 0.00990680883217194
GO:CC GO:0000307 cyclin-dependent protein kinase holoenzyme complex 1.10150494280616e-09 43 34 6 0.176470588235294 0.13953488372093
GO:CC GO:0000778 condensed nuclear chromosome kinetochore 1.14714098239698e-09 18 86 6 0.0697674418604651 0.333333333333333
GO:CC GO:0000228 nuclear chromosome 1.31000911940722e-09 252 107 14 0.130841121495327 0.0555555555555556
GO:CC GO:0000942 condensed nuclear chromosome outer kinetochore 3.32516222740614e-09 4 86 4 0.0465116279069767 1
GO:CC GO:0043226 organelle 5.30855811513784e-09 14008 137 129 0.941605839416058 0.00920902341519132
GO:CC GO:0032991 protein-containing complex 5.62125429159419e-09 5548 136 74 0.544117647058823 0.0133381398702235
GO:CC GO:0043231 intracellular membrane-bounded organelle 6.26410015081954e-09 11296 136 114 0.838235294117647 0.0100920679886686
GO:CC GO:0000796 condensin complex 7.47049701738841e-09 8 136 5 0.0367647058823529 0.625
GO:CC GO:0032133 chromosome passenger complex 1.70009283683908e-08 6 68 4 0.0588235294117647 0.666666666666667
GO:CC GO:0045171 intercellular bridge 1.83324354851045e-08 76 89 8 0.0898876404494382 0.105263157894737
GO:CC GO:0000794 condensed nuclear chromosome 4.86474294003643e-08 89 86 8 0.0930232558139535 0.0898876404494382
GO:CC GO:1902554 serine/threonine protein kinase complex 7.2136928265261e-08 88 34 6 0.176470588235294 0.0681818181818182
GO:CC GO:1990023 mitotic spindle midzone 1.29282529307311e-07 14 121 5 0.0413223140495868 0.357142857142857
GO:CC GO:1902911 protein kinase complex 1.90307306947399e-07 104 34 6 0.176470588235294 0.0576923076923077
GO:CC GO:0097149 centralspindlin complex 3.08115765099521e-07 3 69 3 0.0434782608695652 1
GO:CC GO:0031262 Ndc80 complex 2.31218451508771e-06 4 86 3 0.0348837209302326 0.75
GO:CC GO:0031617 NMS complex 2.31218451508771e-06 4 86 3 0.0348837209302326 0.75
GO:CC GO:0031461 cullin-RING ubiquitin ligase complex 2.39224117113011e-06 166 18 5 0.277777777777778 0.0301204819277108
GO:CC GO:0005680 anaphase-promoting complex 3.13906563932424e-06 24 13 3 0.230769230769231 0.125
GO:CC GO:0032153 cell division site 3.75970023245348e-06 72 130 7 0.0538461538461538 0.0972222222222222
GO:CC GO:0043227 membrane-bounded organelle 4.01431713929823e-06 12858 137 118 0.861313868613139 0.00917716596671333
GO:CC GO:0045120 pronucleus 6.12738843372548e-06 14 28 3 0.107142857142857 0.214285714285714
GO:CC GO:1990752 microtubule end 8.0953966881701e-06 34 109 5 0.0458715596330275 0.147058823529412
GO:CC GO:0032154 cleavage furrow 1.04185610998183e-05 54 130 6 0.0461538461538462 0.111111111111111
GO:CC GO:0000152 nuclear ubiquitin ligase complex 1.94382181344348e-05 45 13 3 0.230769230769231 0.0666666666666667
GO:CC GO:1990234 transferase complex 2.76250948992544e-05 804 18 7 0.388888888888889 0.00870646766169154
GO:CC GO:0000151 ubiquitin ligase complex 3.54535489987883e-05 297 18 5 0.277777777777778 0.0168350168350168
GO:CC GO:0061695 transferase complex, transferring phosphorus-containing groups 3.76235559119467e-05 267 34 6 0.176470588235294 0.0224719101123595
GO:CC GO:0140513 nuclear protein-containing complex 3.88583966828855e-05 1249 135 24 0.177777777777778 0.0192153722978383
GO:CC GO:0005730 nucleolus 4.52619239102168e-05 955 131 20 0.152671755725191 0.0209424083769634
GO:CC GO:0035371 microtubule plus-end 5.08248446424394e-05 24 109 4 0.036697247706422 0.166666666666667
GO:CC GO:0031616 spindle pole centrosome 5.93967614292346e-05 16 54 3 0.0555555555555556 0.1875
GO:CC GO:0070938 contractile ring 7.69545634822549e-05 10 98 3 0.0306122448979592 0.3
GO:CC GO:0090543 Flemming body 7.81690552640903e-05 35 83 4 0.0481927710843374 0.114285714285714
GO:CC GO:0097539 ciliary transition fiber 0.000120003897539566 9 129 3 0.0232558139534884 0.333333333333333
GO:CC GO:0072687 meiotic spindle 0.000139138647271978 14 84 3 0.0357142857142857 0.214285714285714
GO:CC GO:0034451 centriolar satellite 0.00016521764699733 107 109 6 0.055045871559633 0.0560747663551402
GO:CC GO:0033648 host intracellular membrane-bounded organelle 0.000238226288365734 143 28 4 0.142857142857143 0.027972027972028
GO:CC GO:0033647 host intracellular organelle 0.000238226288365734 143 28 4 0.142857142857143 0.027972027972028
GO:CC GO:0005814 centriole 0.000238226288365734 142 129 7 0.0542635658914729 0.0492957746478873
GO:CC GO:0042025 host cell nucleus 0.000238226288365734 143 28 4 0.142857142857143 0.027972027972028
GO:CC GO:0043656 host intracellular region 0.000250019725633135 146 28 4 0.142857142857143 0.0273972602739726
GO:CC GO:0033646 host intracellular part 0.000250019725633135 146 28 4 0.142857142857143 0.0273972602739726
GO:CC GO:0010369 chromocenter 0.000250019725633135 15 99 3 0.0303030303030303 0.2
GO:CC GO:0033643 host cell part 0.000252914452470425 147 28 4 0.142857142857143 0.0272108843537415
GO:CC GO:0099568 cytoplasmic region 0.000314654378781724 269 98 8 0.0816326530612245 0.0297397769516729
GO:CC GO:0016363 nuclear matrix 0.000321259781735614 110 76 5 0.0657894736842105 0.0454545454545455
GO:CC GO:0005881 cytoplasmic microtubule 0.000498588604473846 76 121 5 0.0413223140495868 0.0657894736842105
GO:CC GO:0043657 host cell 0.000643365220620199 198 78 6 0.0769230769230769 0.0303030303030303
GO:CC GO:0018995 host cellular component 0.000643365220620199 198 78 6 0.0769230769230769 0.0303030303030303
GO:CC GO:0034399 nuclear periphery 0.000725278037881519 132 76 5 0.0657894736842105 0.0378787878787879
GO:CC GO:0048471 perinuclear region of cytoplasm 0.000725525758304679 735 23 6 0.260869565217391 0.00816326530612245
GO:CC GO:1902494 catalytic complex 0.000812089308354922 1441 18 7 0.388888888888889 0.00485773768216516
GO:CC GO:0044815 DNA packaging complex 0.000812089308354922 119 136 6 0.0441176470588235 0.0504201680672269
GO:CC GO:0140535 intracellular protein-containing complex 0.00215384450199986 767 18 5 0.277777777777778 0.00651890482398957
GO:CC GO:0016604 nuclear body 0.00405114307487062 816 127 14 0.110236220472441 0.017156862745098
GO:CC GO:0099738 cell cortex region 0.00465505755939497 42 98 3 0.0306122448979592 0.0714285714285714
GO:CC GO:0016607 nuclear speck 0.00626036094442292 412 127 9 0.0708661417322835 0.0218446601941748
GO:CC GO:0032838 plasma membrane bounded cell projection cytoplasm 0.00721466153972939 226 76 5 0.0657894736842105 0.0221238938053097
GO:CC GO:0005643 nuclear pore 0.00999696884983002 85 133 4 0.0300751879699248 0.0470588235294118
GO:CC GO:0120111 neuron projection cytoplasm 0.0130764281345357 93 133 4 0.0300751879699248 0.043010752688172
GO:CC GO:1904115 axon cytoplasm 0.0249425040149471 62 133 3 0.0225563909774436 0.0483870967741935
GO:MF GO:0008017 microtubule binding 2.08276480647663e-22 271 132 28 0.212121212121212 0.103321033210332
GO:MF GO:0015631 tubulin binding 5.81686853671057e-20 376 132 29 0.21969696969697 0.0771276595744681
GO:MF GO:0003777 microtubule motor activity 1.72586984889756e-10 76 121 11 0.0909090909090909 0.144736842105263
GO:MF GO:0008092 cytoskeletal protein binding 1.72586984889756e-10 996 110 28 0.254545454545455 0.0281124497991968
GO:MF GO:0003774 motor activity 3.67373353104084e-09 134 121 12 0.0991735537190083 0.0895522388059701
GO:MF GO:0035639 purine ribonucleoside triphosphate binding 1.00122001185496e-07 1847 125 36 0.288 0.0194910665944775
GO:MF GO:0019900 kinase binding 1.85897509705293e-07 752 114 21 0.184210526315789 0.0279255319148936
GO:MF GO:0032555 purine ribonucleotide binding 2.05839340824782e-07 1918 125 36 0.288 0.0187695516162669
GO:MF GO:0032553 ribonucleotide binding 2.08014200033322e-07 1935 125 36 0.288 0.0186046511627907
GO:MF GO:0017076 purine nucleotide binding 2.08014200033322e-07 1933 125 36 0.288 0.0186239006725297
GO:MF GO:0016538 cyclin-dependent protein serine/threonine kinase regulator activity 2.08845291284041e-07 48 28 5 0.178571428571429 0.104166666666667
GO:MF GO:0000166 nucleotide binding 2.86510290550566e-07 2171 125 38 0.304 0.0175034546292031
GO:MF GO:1901265 nucleoside phosphate binding 2.86510290550566e-07 2172 125 38 0.304 0.0174953959484346
GO:MF GO:0019901 protein kinase binding 4.6520051716754e-07 673 114 19 0.166666666666667 0.0282317979197623
GO:MF GO:0017111 nucleoside-triphosphatase activity 6.97639280898405e-07 872 121 22 0.181818181818182 0.0252293577981651
GO:MF GO:0019899 enzyme binding 7.91095000989319e-07 2074 125 36 0.288 0.017357762777242
GO:MF GO:0010997 anaphase-promoting complex binding 7.91407470473609e-07 8 19 3 0.157894736842105 0.375
GO:MF GO:0008574 ATP-dependent microtubule motor activity, plus-end-directed 8.94084647358675e-07 17 121 5 0.0413223140495868 0.294117647058824
GO:MF GO:0061575 cyclin-dependent protein serine/threonine kinase activator activity 8.94084647358675e-07 9 18 3 0.166666666666667 0.333333333333333
GO:MF GO:0016462 pyrophosphatase activity 1.40535734251543e-06 928 121 22 0.181818181818182 0.0237068965517241
GO:MF GO:0016817 hydrolase activity, acting on acid anhydrides 1.40535734251543e-06 930 121 22 0.181818181818182 0.0236559139784946
GO:MF GO:0016818 hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides 1.40535734251543e-06 930 121 22 0.181818181818182 0.0236559139784946
GO:MF GO:1990939 ATP-dependent microtubule motor activity 1.40535734251543e-06 36 121 6 0.0495867768595041 0.166666666666667
GO:MF GO:0005524 ATP binding 1.66334729769292e-06 1501 132 30 0.227272727272727 0.0199866755496336
GO:MF GO:0097367 carbohydrate derivative binding 1.85425886486416e-06 2285 110 34 0.309090909090909 0.0148796498905908
GO:MF GO:0005515 protein binding 2.95631845859755e-06 14767 117 112 0.957264957264957 0.00758447890566804
GO:MF GO:0019887 protein kinase regulator activity 3.30420632268885e-06 191 28 6 0.214285714285714 0.031413612565445
GO:MF GO:0032559 adenyl ribonucleotide binding 3.44686460382311e-06 1565 125 29 0.232 0.0185303514376997
GO:MF GO:0030554 adenyl nucleotide binding 3.95453219076541e-06 1578 125 29 0.232 0.0183776932826362
GO:MF GO:0008022 protein C-terminus binding 5.20613953002945e-06 202 46 7 0.152173913043478 0.0346534653465347
GO:MF GO:0036094 small molecule binding 5.20613953002945e-06 2506 125 38 0.304 0.0151636073423783
GO:MF GO:0043168 anion binding 5.55174974793563e-06 2418 73 26 0.356164383561644 0.010752688172043
GO:MF GO:0019207 kinase regulator activity 6.36139373727829e-06 221 28 6 0.214285714285714 0.0271493212669683
GO:MF GO:0030295 protein kinase activator activity 9.24862200069527e-06 85 18 4 0.222222222222222 0.0470588235294118
GO:MF GO:0019209 kinase activator activity 1.18164850170526e-05 91 18 4 0.222222222222222 0.043956043956044
GO:MF GO:0008301 DNA binding, bending 3.02094634400328e-05 18 33 3 0.0909090909090909 0.166666666666667
GO:MF GO:0043539 protein serine/threonine kinase activator activity 5.30022261455942e-05 40 18 3 0.166666666666667 0.075
GO:MF GO:0043515 kinetochore binding 5.70200769275549e-05 7 116 3 0.0258620689655172 0.428571428571429
GO:MF GO:0030234 enzyme regulator activity 5.72871353063505e-05 1248 61 15 0.245901639344262 0.0120192307692308
GO:MF GO:0016887 ATPase activity 6.35017079627178e-05 488 132 14 0.106060606060606 0.0286885245901639
GO:MF GO:0003682 chromatin binding 7.30972899199057e-05 571 115 14 0.121739130434783 0.0245183887915937
GO:MF GO:0035173 histone kinase activity 8.00983112082318e-05 16 54 3 0.0555555555555556 0.1875
GO:MF GO:0004712 protein serine/threonine/tyrosine kinase activity 8.49562421807818e-05 44 62 4 0.0645161290322581 0.0909090909090909
GO:MF GO:0043130 ubiquitin binding 0.000403883401906503 83 18 3 0.166666666666667 0.036144578313253
GO:MF GO:0004674 protein serine/threonine kinase activity 0.000602322666473387 441 62 8 0.129032258064516 0.018140589569161
GO:MF GO:0032182 ubiquitin-like protein binding 0.000672953234507557 100 18 3 0.166666666666667 0.03
GO:MF GO:0042826 histone deacetylase binding 0.00069334158687867 116 16 3 0.1875 0.0258620689655172
GO:MF GO:0098772 molecular function regulator 0.000747406128284056 2363 18 9 0.5 0.003808717731697
GO:MF GO:0051010 microtubule plus-end binding 0.00150672332266988 20 121 3 0.0247933884297521 0.15
GO:MF GO:0008047 enzyme activator activity 0.00248156155280462 540 97 10 0.103092783505155 0.0185185185185185
GO:MF GO:0004672 protein kinase activity 0.00332065306732991 587 62 8 0.129032258064516 0.0136286201022147
GO:MF GO:0016301 kinase activity 0.00542556708096964 796 62 9 0.145161290322581 0.0113065326633166
GO:MF GO:0003725 double-stranded RNA binding 0.00757097455166643 77 58 3 0.0517241379310345 0.038961038961039
GO:MF GO:0003924 GTPase activity 0.0080582509465127 328 100 7 0.07 0.0213414634146341
GO:MF GO:0016773 phosphotransferase activity, alcohol group as acceptor 0.00806617569679509 692 62 8 0.129032258064516 0.0115606936416185
GO:MF GO:0046983 protein dimerization activity 0.00901194663048844 1069 61 10 0.163934426229508 0.00935453695042095
GO:MF GO:0046982 protein heterodimerization activity 0.0104477768840477 357 31 4 0.129032258064516 0.0112044817927171
GO:MF GO:0042393 histone binding 0.0138353654704366 241 115 6 0.0521739130434783 0.024896265560166
GO:MF GO:0016772 transferase activity, transferring phosphorus-containing groups 0.0142668327490371 952 62 9 0.145161290322581 0.00945378151260504
GO:MF GO:0005525 GTP binding 0.0150148653704293 381 100 7 0.07 0.0183727034120735
GO:MF GO:1901363 heterocyclic compound binding 0.0154000099012198 6228 89 42 0.471910112359551 0.00674373795761079
GO:MF GO:0032550 purine ribonucleoside binding 0.0157128902629356 386 100 7 0.07 0.0181347150259067
GO:MF GO:0032549 ribonucleoside binding 0.0159871161980139 389 100 7 0.07 0.0179948586118252
GO:MF GO:0001883 purine nucleoside binding 0.0159871161980139 389 100 7 0.07 0.0179948586118252
GO:MF GO:0001882 nucleoside binding 0.0171489584934261 395 100 7 0.07 0.0177215189873418
GO:MF GO:0097159 organic cyclic compound binding 0.0183556092379893 6309 89 42 0.471910112359551 0.00665715644317641
GO:MF GO:0032561 guanyl ribonucleotide binding 0.0183556092379893 403 100 7 0.07 0.0173697270471464
GO:MF GO:0019001 guanyl nucleotide binding 0.0183556092379893 403 100 7 0.07 0.0173697270471464
GO:MF GO:0106310 protein serine kinase activity 0.0191206240197872 249 56 4 0.0714285714285714 0.0160642570281124
GO:MF GO:0106311 protein threonine kinase activity 0.0191206240197872 248 56 4 0.0714285714285714 0.0161290322580645
GO:MF GO:0019904 protein domain specific binding 0.0206819178129109 710 46 6 0.130434782608696 0.00845070422535211
GO:MF GO:0042802 identical protein binding 0.0220786136150017 2067 76 16 0.210526315789474 0.00774068698597
GO:MF GO:0140104 molecular carrier activity 0.0234228424717003 68 117 3 0.0256410256410256 0.0441176470588235
GO:MF GO:0045296 cadherin binding 0.0290313739871904 333 137 7 0.0510948905109489 0.021021021021021
GO:MF GO:0005102 signaling receptor binding 0.0290313739871904 1672 6 3 0.5 0.00179425837320574
GO:MF GO:0000287 magnesium ion binding 0.0323791778778898 222 118 5 0.0423728813559322 0.0225225225225225
GO:MF GO:0005096 GTPase activator activity 0.0348060665096728 278 133 6 0.0451127819548872 0.0215827338129496
GO:MF GO:0003723 RNA binding 0.0391163921355999 1943 59 12 0.203389830508475 0.00617601646937725
GO:MF GO:0005488 binding 0.0414184024824746 17074 86 84 0.976744186046512 0.00491976104017805
GO:MF GO:0042803 protein homodimerization activity 0.0440618524365089 676 76 7 0.0921052631578947 0.0103550295857988
HPA HPA:0570763 testis; pachytene spermatocytes[High] 1.3673429038743e-07 822 122 32 0.262295081967213 0.0389294403892944
HPA HPA:0310433 lymph node; germinal center cells[High] 1.60528745514176e-05 908 107 27 0.252336448598131 0.0297356828193833
HPA HPA:0570762 testis; pachytene spermatocytes[≥Medium] 1.60528745514176e-05 1658 122 42 0.344262295081967 0.0253317249698432
HPA HPA:0570761 testis; pachytene spermatocytes[≥Low] 1.60528745514176e-05 2077 123 49 0.398373983739837 0.0235917188252287
HPA HPA:0310432 lymph node; germinal center cells[≥Medium] 0.000223235258582331 3209 16 14 0.875 0.00436272982237457
HPA HPA:0600433 tonsil; germinal center cells[High] 0.000549530370211903 1179 107 28 0.261682242990654 0.0237489397794741
HPA HPA:0381191 placenta; cytotrophoblasts[≥Low] 0.00129243942454536 303 133 14 0.105263157894737 0.0462046204620462
HPA HPA:0040083 bone marrow; hematopoietic cells[High] 0.00144000816423067 1376 109 30 0.275229357798165 0.0218023255813953
HPA HPA:0500703 soft tissue 1; peripheral nerve[High] 0.00160845704288398 225 118 11 0.0932203389830508 0.0488888888888889
HPA HPA:0600432 tonsil; germinal center cells[≥Medium] 0.00185519846628457 3988 16 14 0.875 0.00351053159478435
HPA HPA:0570781 testis; preleptotene spermatocytes[≥Low] 0.00185519846628457 1636 123 36 0.292682926829268 0.0220048899755501
HPA HPA:0381192 placenta; cytotrophoblasts[≥Medium] 0.00280954358277456 272 57 8 0.140350877192982 0.0294117647058824
HPA HPA:0310431 lymph node; germinal center cells[≥Low] 0.00280954358277456 4935 28 23 0.821428571428571 0.00466058763931104
HPA HPA:0470682 skin 2; epidermal cells[≥Medium] 0.0112983045099946 4735 19 16 0.842105263157895 0.00337909186906019
HPA HPA:0040082 bone marrow; hematopoietic cells[≥Medium] 0.0126835886947776 4126 8 8 1 0.00193892389723703
HPA HPA:0030072 appendix; lymphoid tissue[≥Medium] 0.0126835886947776 3131 13 10 0.769230769230769 0.00319386777387416
HPA HPA:0530721 spleen; cells in white pulp[≥Low] 0.014065479791082 4249 8 8 1 0.0018827959519887
HPA HPA:0510703 soft tissue 2; peripheral nerve[High] 0.014065479791082 263 118 10 0.0847457627118644 0.0380228136882129
HPA HPA:0030071 appendix; lymphoid tissue[≥Low] 0.0171304031753444 4976 16 14 0.875 0.00281350482315113
HPA HPA:0500653 soft tissue 1; fibroblasts[High] 0.0225640700322782 509 104 13 0.125 0.0255402750491159
HPA HPA:0510111 soft tissue 2; chondrocytes[≥Low] 0.0225640700322782 1055 6 4 0.666666666666667 0.0037914691943128
HPA HPA:0381201 placenta; hofbauer cells[≥Low] 0.0225640700322782 254 133 10 0.075187969924812 0.0393700787401575
HPA HPA:0620221 vagina; squamous epithelial cells[≥Low] 0.0344104956766455 5868 28 23 0.821428571428571 0.00391956373551466
HPA HPA:0600431 tonsil; germinal center cells[≥Low] 0.0344104956766455 5845 28 23 0.821428571428571 0.0039349871685201
HPA HPA:0190222 esophagus; squamous epithelial cells[≥Medium] 0.0344104956766455 4937 8 8 1 0.00162041725744379
HPA HPA:0620000 vagina 0.0344104956766455 5868 28 23 0.821428571428571 0.00391956373551466
HPA HPA:0310000 lymph node 0.0381234975934081 6374 28 24 0.857142857142857 0.00376529651710072
KEGG KEGG:04110 Cell cycle 2.07189281740497e-08 124 119 15 0.126050420168067 0.120967741935484
KEGG KEGG:04114 Oocyte meiosis 1.32727467234964e-06 127 34 8 0.235294117647059 0.062992125984252
KEGG KEGG:04914 Progesterone-mediated oocyte maturation 2.55188778130769e-06 98 114 11 0.0964912280701754 0.112244897959184
KEGG KEGG:05166 Human T-cell leukemia virus 1 infection 0.0108196087133357 216 28 5 0.178571428571429 0.0231481481481481
KEGG KEGG:04115 p53 signaling pathway 0.0108196087133357 73 48 4 0.0833333333333333 0.0547945205479452
KEGG KEGG:04540 Gap junction 0.0108196087133357 88 41 4 0.0975609756097561 0.0454545454545455
KEGG KEGG:04120 Ubiquitin mediated proteolysis 0.0118098412879169 139 13 3 0.230769230769231 0.0215827338129496
KEGG KEGG:04068 FoxO signaling pathway 0.0274470356727602 131 19 3 0.157894736842105 0.0229007633587786
KEGG KEGG:04218 Cellular senescence 0.0290840500366512 156 34 4 0.117647058823529 0.0256410256410256
MIRNA MIRNA:hsa-miR-215-5p hsa-miR-215-5p 5.85582720039078e-19 753 136 42 0.308823529411765 0.0557768924302789
MIRNA MIRNA:hsa-miR-192-5p hsa-miR-192-5p 7.74547064882087e-15 989 136 42 0.308823529411765 0.0424671385237614
MIRNA MIRNA:hsa-miR-193b-3p hsa-miR-193b-3p 1.2133685618669e-11 847 136 35 0.257352941176471 0.0413223140495868
MIRNA MIRNA:hsa-let-7a-2-3p hsa-let-7a-2-3p 0.000208036246080467 102 11 4 0.363636363636364 0.0392156862745098
MIRNA MIRNA:hsa-let-7b-5p hsa-let-7b-5p 0.000208036246080467 1212 28 12 0.428571428571429 0.0099009900990099
MIRNA MIRNA:hsa-let-7g-3p hsa-let-7g-3p 0.000208036246080467 106 11 4 0.363636363636364 0.0377358490566038
MIRNA MIRNA:hsa-miR-221-3p hsa-miR-221-3p 0.00557712810410689 366 114 12 0.105263157894737 0.0327868852459016
MIRNA MIRNA:hsa-miR-187-5p hsa-miR-187-5p 0.00558034987272598 84 11 3 0.272727272727273 0.0357142857142857
MIRNA MIRNA:hsa-miR-6507-5p hsa-miR-6507-5p 0.00581329080360551 132 70 6 0.0857142857142857 0.0454545454545455
MIRNA MIRNA:hsa-miR-425-5p hsa-miR-425-5p 0.00581329080360551 144 94 7 0.074468085106383 0.0486111111111111
MIRNA MIRNA:hsa-miR-16-5p hsa-miR-16-5p 0.00682730962553531 1556 15 8 0.533333333333333 0.0051413881748072
MIRNA MIRNA:hsa-miR-92a-3p hsa-miR-92a-3p 0.00705112351439726 1404 63 17 0.26984126984127 0.0121082621082621
MIRNA MIRNA:hsa-miR-1226-3p hsa-miR-1226-3p 0.0101511768821137 226 16 4 0.25 0.0176991150442478
MIRNA MIRNA:hsa-miR-23b-3p hsa-miR-23b-3p 0.017920813858572 319 14 4 0.285714285714286 0.0125391849529781
MIRNA MIRNA:hsa-miR-186-5p hsa-miR-186-5p 0.017920813858572 749 125 17 0.136 0.0226969292389853
MIRNA MIRNA:hsa-miR-3653-3p hsa-miR-3653-3p 0.017920813858572 129 60 5 0.0833333333333333 0.0387596899224806
MIRNA MIRNA:hsa-miR-6715a-3p hsa-miR-6715a-3p 0.0203765454521692 80 55 4 0.0727272727272727 0.05
MIRNA MIRNA:hsa-miR-17-5p hsa-miR-17-5p 0.0227030707313631 1174 13 6 0.461538461538462 0.00511073253833049
MIRNA MIRNA:hsa-miR-3658 hsa-miR-3658 0.0272570491789111 148 60 5 0.0833333333333333 0.0337837837837838
MIRNA MIRNA:hsa-miR-3168 hsa-miR-3168 0.0356725194935514 31 72 3 0.0416666666666667 0.0967741935483871
MIRNA MIRNA:hsa-miR-371b-3p hsa-miR-371b-3p 0.0402601168783826 54 107 4 0.0373831775700935 0.0740740740740741
MIRNA MIRNA:hsa-miR-222-3p hsa-miR-222-3p 0.0402601168783826 393 107 10 0.0934579439252336 0.0254452926208651
MIRNA MIRNA:hsa-miR-497-3p hsa-miR-497-3p 0.0402601168783826 99 57 4 0.0701754385964912 0.0404040404040404
MIRNA MIRNA:hsa-miR-188-5p hsa-miR-188-5p 0.0402601168783826 112 52 4 0.0769230769230769 0.0357142857142857
MIRNA MIRNA:hsa-miR-5584-3p hsa-miR-5584-3p 0.0402601168783826 79 72 4 0.0555555555555556 0.0506329113924051
MIRNA MIRNA:hsa-let-7e-5p hsa-let-7e-5p 0.0430456187343962 608 60 9 0.15 0.0148026315789474
MIRNA MIRNA:hsa-miR-548az-5p hsa-miR-548az-5p 0.0487253129737428 267 11 3 0.272727272727273 0.0112359550561798
MIRNA MIRNA:hsa-miR-548t-5p hsa-miR-548t-5p 0.0487253129737428 267 11 3 0.272727272727273 0.0112359550561798
REAC REAC:R-HSA-1640170 Cell Cycle 1.15689184813526e-39 642 121 61 0.504132231404959 0.0950155763239875
REAC REAC:R-HSA-69278 Cell Cycle, Mitotic 1.56418935440233e-39 513 136 59 0.433823529411765 0.115009746588694
REAC REAC:R-HSA-68877 Mitotic Prometaphase 3.06748320056113e-38 199 136 42 0.308823529411765 0.21105527638191
REAC REAC:R-HSA-68886 M Phase 8.09949811599799e-34 371 136 48 0.352941176470588 0.129380053908356
REAC REAC:R-HSA-2500257 Resolution of Sister Chromatid Cohesion 9.27114520562271e-34 123 133 33 0.24812030075188 0.268292682926829
REAC REAC:R-HSA-68882 Mitotic Anaphase 4.29502365124811e-30 228 78 31 0.397435897435897 0.135964912280702
REAC REAC:R-HSA-2555396 Mitotic Metaphase and Anaphase 4.29502365124811e-30 229 78 31 0.397435897435897 0.135371179039301
REAC REAC:R-HSA-9648025 EML4 and NUDC in mitotic spindle formation 9.38503706530282e-29 115 133 29 0.218045112781955 0.252173913043478
REAC REAC:R-HSA-2467813 Separation of Sister Chromatids 1.53685965745255e-27 188 121 32 0.264462809917355 0.170212765957447
REAC REAC:R-HSA-5663220 RHO GTPases Activate Formins 1.42117291956048e-26 136 133 29 0.218045112781955 0.213235294117647
REAC REAC:R-HSA-69618 Mitotic Spindle Checkpoint 1.42117291956048e-26 109 133 27 0.203007518796992 0.247706422018349
REAC REAC:R-HSA-141424 Amplification of signal from the kinetochores 1.04059296140891e-25 92 133 25 0.18796992481203 0.271739130434783
REAC REAC:R-HSA-141444 Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal 1.04059296140891e-25 92 133 25 0.18796992481203 0.271739130434783
REAC REAC:R-HSA-69620 Cell Cycle Checkpoints 8.8705324100808e-24 271 86 29 0.337209302325581 0.107011070110701
REAC REAC:R-HSA-195258 RHO GTPase Effectors 7.68758818969199e-21 283 121 31 0.256198347107438 0.109540636042403
REAC REAC:R-HSA-194315 Signaling by Rho GTPases 4.68895816455398e-20 413 121 35 0.289256198347107 0.0847457627118644
REAC REAC:R-HSA-9716542 Signaling by Rho GTPases, Miro GTPases and RHOBTB3 4.68895816455398e-20 413 121 35 0.289256198347107 0.0847457627118644
REAC REAC:R-HSA-69275 G2/M Transition 3.01405432342415e-15 196 48 16 0.333333333333333 0.0816326530612245
REAC REAC:R-HSA-983189 Kinesins 3.01405432342415e-15 61 121 15 0.12396694214876 0.245901639344262
REAC REAC:R-HSA-453274 Mitotic G2-G2/M phases 3.37078728889483e-15 198 48 16 0.333333333333333 0.0808080808080808
REAC REAC:R-HSA-174143 APC/C-mediated degradation of cell cycle proteins 3.11093488065855e-14 88 34 11 0.323529411764706 0.125
REAC REAC:R-HSA-453276 Regulation of mitotic cell cycle 3.11093488065855e-14 88 34 11 0.323529411764706 0.125
REAC REAC:R-HSA-176814 Activation of APC/C and APC/C:Cdc20 mediated degradation of mitotic proteins 4.54592155965634e-13 77 34 10 0.294117647058824 0.12987012987013
REAC REAC:R-HSA-2514853 Condensation of Prometaphase Chromosomes 1.61332850051634e-12 11 136 8 0.0588235294117647 0.727272727272727
REAC REAC:R-HSA-6811434 COPI-dependent Golgi-to-ER retrograde traffic 5.67037939528937e-12 100 121 15 0.12396694214876 0.15
REAC REAC:R-HSA-8856688 Golgi-to-ER retrograde transport 7.62879123105105e-12 134 130 17 0.130769230769231 0.126865671641791
REAC REAC:R-HSA-176409 APC/C:Cdc20 mediated degradation of mitotic proteins 2.10995512106647e-11 76 34 9 0.264705882352941 0.118421052631579
REAC REAC:R-HSA-2132295 MHC class II antigen presentation 3.22878303676753e-10 123 130 15 0.115384615384615 0.121951219512195
REAC REAC:R-HSA-2565942 Regulation of PLK1 Activity at G2/M Transition 3.87246649350494e-10 85 130 13 0.1 0.152941176470588
REAC REAC:R-HSA-8854518 AURKA Activation by TPX2 6.61783973814016e-10 71 130 12 0.0923076923076923 0.169014084507042
REAC REAC:R-HSA-176408 Regulation of APC/C activators between G1/S and early anaphase 1.6526324357353e-09 81 34 8 0.235294117647059 0.0987654320987654
REAC REAC:R-HSA-983231 Factors involved in megakaryocyte development and platelet production 2.56740734163882e-09 154 121 15 0.12396694214876 0.0974025974025974
REAC REAC:R-HSA-6811442 Intra-Golgi and retrograde Golgi-to-ER traffic 4.99468063853653e-09 203 130 17 0.130769230769231 0.083743842364532
REAC REAC:R-HSA-176417 Phosphorylation of Emi1 1.53984352352585e-08 6 34 4 0.117647058823529 0.666666666666667
REAC REAC:R-HSA-380320 Recruitment of NuMA to mitotic centrosomes 1.66518405695583e-08 94 130 12 0.0923076923076923 0.127659574468085
REAC REAC:R-HSA-8852276 The role of GTSE1 in G2/M progression after G2 checkpoint 2.21516471810409e-08 79 48 8 0.166666666666667 0.10126582278481
REAC REAC:R-HSA-179419 APC:Cdc20 mediated degradation of cell cycle proteins prior to satisfation of the cell cycle checkpoint 3.05346294162575e-08 74 34 7 0.205882352941176 0.0945945945945946
REAC REAC:R-HSA-2980767 Activation of NIMA Kinases NEK9, NEK6, NEK7 3.2074404425748e-08 7 34 4 0.117647058823529 0.571428571428571
REAC REAC:R-HSA-176412 Phosphorylation of the APC/C 3.83342774962237e-08 20 34 5 0.147058823529412 0.25
REAC REAC:R-HSA-69273 Cyclin A/B1/B2 associated events during G2/M transition 5.71354444418419e-08 25 114 7 0.0614035087719298 0.28
REAC REAC:R-HSA-174178 APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1 8.47701337198806e-08 74 23 6 0.260869565217391 0.0810810810810811
REAC REAC:R-HSA-174048 APC/C:Cdc20 mediated degradation of Cyclin B 9.66939298174857e-08 24 34 5 0.147058823529412 0.208333333333333
REAC REAC:R-HSA-179409 APC-Cdc20 mediated degradation of Nek2A 1.05647065342552e-07 26 32 5 0.15625 0.192307692307692
REAC REAC:R-HSA-156711 Polo-like kinase mediated events 1.19568084596301e-07 16 19 4 0.210526315789474 0.25
REAC REAC:R-HSA-2995410 Nuclear Envelope (NE) Reassembly 1.31009417834171e-07 70 133 10 0.075187969924812 0.142857142857143
REAC REAC:R-HSA-380287 Centrosome maturation 3.7623795854366e-07 80 130 10 0.0769230769230769 0.125
REAC REAC:R-HSA-380270 Recruitment of mitotic centrosome proteins and complexes 3.7623795854366e-07 80 130 10 0.0769230769230769 0.125
REAC REAC:R-HSA-141430 Inactivation of APC/C via direct inhibition of the APC/C complex 4.38266872927964e-07 21 20 4 0.2 0.19047619047619
REAC REAC:R-HSA-141405 Inhibition of the proteolytic activity of APC/C required for the onset of anaphase by mitotic spindle checkpoint components 4.38266872927964e-07 21 20 4 0.2 0.19047619047619
REAC REAC:R-HSA-162658 Golgi Cisternae Pericentriolar Stack Reorganization 4.91213119172623e-07 13 34 4 0.117647058823529 0.307692307692308
REAC REAC:R-HSA-174184 Cdc20:Phospho-APC/C mediated degradation of Cyclin A 7.86766138449369e-07 73 34 6 0.176470588235294 0.0821917808219178
REAC REAC:R-HSA-380259 Loss of Nlp from mitotic centrosomes 9.762758118613e-07 68 130 9 0.0692307692307692 0.132352941176471
REAC REAC:R-HSA-380284 Loss of proteins required for interphase microtubule organization from the centrosome 9.762758118613e-07 68 130 9 0.0692307692307692 0.132352941176471
REAC REAC:R-HSA-5620912 Anchoring of the basal body to the plasma membrane 1.89935649732481e-06 96 130 10 0.0769230769230769 0.104166666666667
REAC REAC:R-HSA-69478 G2/M DNA replication checkpoint 2.15795638400548e-06 5 34 3 0.0882352941176471 0.6
REAC REAC:R-HSA-4615885 SUMOylation of DNA replication proteins 4.5958608862607e-06 43 78 6 0.0769230769230769 0.13953488372093
REAC REAC:R-HSA-174154 APC/C:Cdc20 mediated degradation of Securin 7.39241996213406e-06 68 13 4 0.307692307692308 0.0588235294117647
REAC REAC:R-HSA-5617833 Cilium Assembly 7.39759196665154e-06 201 130 13 0.1 0.0646766169154229
REAC REAC:R-HSA-176407 Conversion from APC/C:Cdc20 to APC/C:Cdh1 in late anaphase 1.08766228148044e-05 20 13 3 0.230769230769231 0.15
REAC REAC:R-HSA-68884 Mitotic Telophase/Cytokinesis 2.07540805696591e-05 13 89 4 0.0449438202247191 0.307692307692308
REAC REAC:R-HSA-3371497 HSP90 chaperone cycle for steroid hormone receptors (SHR) 3.72164609049145e-05 57 130 7 0.0538461538461538 0.12280701754386
REAC REAC:R-HSA-389960 Formation of tubulin folding intermediates by CCT/TriC 7.30865624238518e-05 26 125 5 0.04 0.192307692307692
REAC REAC:R-HSA-774815 Nucleosome assembly 7.87849969185471e-05 50 111 6 0.0540540540540541 0.12
REAC REAC:R-HSA-606279 Deposition of new CENPA-containing nucleosomes at the centromere 7.87849969185471e-05 50 111 6 0.0540540540540541 0.12
REAC REAC:R-HSA-2980766 Nuclear Envelope Breakdown 8.59112392449206e-05 47 34 4 0.117647058823529 0.0851063829787234
REAC REAC:R-HSA-2299718 Condensation of Prophase Chromosomes 8.59112392449206e-05 37 43 4 0.0930232558139535 0.108108108108108
REAC REAC:R-HSA-2995383 Initiation of Nuclear Envelope (NE) Reformation 9.68220400056128e-05 16 34 3 0.0882352941176471 0.1875
REAC REAC:R-HSA-6791312 TP53 Regulates Transcription of Cell Cycle Genes 9.86003368186264e-05 49 34 4 0.117647058823529 0.0816326530612245
REAC REAC:R-HSA-6804114 TP53 Regulates Transcription of Genes Involved in G2 Cell Cycle Arrest 0.00013639103479048 18 34 3 0.0882352941176471 0.166666666666667
REAC REAC:R-HSA-9646399 Aggrephagy 0.000146218742583404 44 42 4 0.0952380952380952 0.0909090909090909
REAC REAC:R-HSA-190840 Microtubule-dependent trafficking of connexons from Golgi to the plasma membrane 0.00017750064624575 20 100 4 0.04 0.2
REAC REAC:R-HSA-73886 Chromosome Maintenance 0.00019884548551074 113 118 8 0.0677966101694915 0.0707964601769911
REAC REAC:R-HSA-389958 Cooperation of Prefoldin and TriC/CCT in actin and tubulin folding 0.000206738174133506 33 125 5 0.04 0.151515151515152
REAC REAC:R-HSA-190872 Transport of connexons to the plasma membrane 0.000208966640847954 21 100 4 0.04 0.19047619047619
REAC REAC:R-HSA-6811436 COPI-independent Golgi-to-ER retrograde traffic 0.000228789869877319 53 130 6 0.0461538461538462 0.113207547169811
REAC REAC:R-HSA-68875 Mitotic Prophase 0.000241715192821926 99 43 5 0.116279069767442 0.0505050505050505
REAC REAC:R-HSA-438064 Post NMDA receptor activation events 0.000284183773371815 76 11 3 0.272727272727273 0.0394736842105263
REAC REAC:R-HSA-389977 Post-chaperonin tubulin folding pathway 0.000289273493879352 23 100 4 0.04 0.173913043478261
REAC REAC:R-HSA-5620924 Intraflagellar transport 0.000289587036842987 54 42 4 0.0952380952380952 0.0740740740740741
REAC REAC:R-HSA-1852241 Organelle biogenesis and maintenance 0.000308925019200508 293 130 13 0.1 0.0443686006825939
REAC REAC:R-HSA-162582 Signal Transduction 0.000370284224113678 2705 87 39 0.448275862068966 0.0144177449168207
REAC REAC:R-HSA-1538133 G0 and Early G1 0.000398419942515296 27 34 3 0.0882352941176471 0.111111111111111
REAC REAC:R-HSA-437239 Recycling pathway of L1 0.000398419942515296 48 100 5 0.05 0.104166666666667
REAC REAC:R-HSA-442755 Activation of NMDA receptors and postsynaptic events 0.00041815364771698 89 11 3 0.272727272727273 0.0337078651685393
REAC REAC:R-HSA-3301854 Nuclear Pore Complex (NPC) Disassembly 0.000435963903280847 33 78 4 0.0512820512820513 0.121212121212121
REAC REAC:R-HSA-453279 Mitotic G1 phase and G1/S transition 0.000456463087252284 148 34 5 0.147058823529412 0.0337837837837838
REAC REAC:R-HSA-9619483 Activation of AMPK downstream of NMDARs 0.000579007837455774 28 100 4 0.04 0.142857142857143
REAC REAC:R-HSA-3108232 SUMO E3 ligases SUMOylate target proteins 0.000650051053102366 156 78 7 0.0897435897435897 0.0448717948717949
REAC REAC:R-HSA-2990846 SUMOylation 0.000806146339990251 162 78 7 0.0897435897435897 0.0432098765432099
REAC REAC:R-HSA-5626467 RHO GTPases activate IQGAPs 0.000934653360268075 32 100 4 0.04 0.125
REAC REAC:R-HSA-9668328 Sealing of the nuclear envelope (NE) by ESCRT-III 0.000934653360268075 32 100 4 0.04 0.125
REAC REAC:R-HSA-9663891 Selective autophagy 0.00113156258745201 80 42 4 0.0952380952380952 0.05
REAC REAC:R-HSA-9609690 HCMV Early Events 0.0011813370178981 96 100 6 0.06 0.0625
REAC REAC:R-HSA-75035 Chk1/Chk2(Cds1) mediated inactivation of Cyclin B:Cdk1 complex 0.00130499424266649 13 114 3 0.0263157894736842 0.230769230769231
REAC REAC:R-HSA-6807878 COPI-mediated anterograde transport 0.00255777087866971 102 42 4 0.0952380952380952 0.0392156862745098
REAC REAC:R-HSA-69206 G1/S Transition 0.00284858761889544 131 34 4 0.117647058823529 0.0305343511450382
REAC REAC:R-HSA-69242 S Phase 0.00294352376000841 162 28 4 0.142857142857143 0.0246913580246914
REAC REAC:R-HSA-3700989 Transcriptional Regulation by TP53 0.00315741614583796 360 34 6 0.176470588235294 0.0166666666666667
REAC REAC:R-HSA-69017 CDK-mediated phosphorylation and removal of Cdc6 0.00317186335744052 73 28 3 0.107142857142857 0.0410958904109589
REAC REAC:R-HSA-112314 Neurotransmitter receptors and postsynaptic signal transmission 0.00319118635369016 196 11 3 0.272727272727273 0.0153061224489796
REAC REAC:R-HSA-9609646 HCMV Infection 0.00323754192912171 120 100 6 0.06 0.05
REAC REAC:R-HSA-2559582 Senescence-Associated Secretory Phenotype (SASP) 0.00344419440930835 76 28 3 0.107142857142857 0.0394736842105263
REAC REAC:R-HSA-6804756 Regulation of TP53 Activity through Phosphorylation 0.00402249997030613 92 54 4 0.0740740740740741 0.0434782608695652
REAC REAC:R-HSA-5633007 Regulation of TP53 Activity 0.00422057061226447 160 54 5 0.0925925925925926 0.03125
REAC REAC:R-HSA-1632852 Macroautophagy 0.00536742576897424 134 100 6 0.06 0.0447761194029851
REAC REAC:R-HSA-199991 Membrane Trafficking 0.00536742576897424 625 130 17 0.130769230769231 0.0272
REAC REAC:R-HSA-69052 Switching of origins to a post-replicative state 0.00546843409570515 91 28 3 0.107142857142857 0.032967032967033
REAC REAC:R-HSA-1280218 Adaptive Immune System 0.00559493662368018 800 8 4 0.5 0.005
REAC REAC:R-HSA-112315 Transmission across Chemical Synapses 0.00644967118920964 259 11 3 0.272727272727273 0.0115830115830116
REAC REAC:R-HSA-597592 Post-translational protein modification 0.00745553126693946 1377 16 7 0.4375 0.00508351488743646
REAC REAC:R-HSA-159236 Transport of Mature mRNA derived from an Intron-Containing Transcript 0.00769713311936779 69 88 4 0.0454545454545455 0.0579710144927536
REAC REAC:R-HSA-9612973 Autophagy 0.00826533073964022 149 42 4 0.0952380952380952 0.0268456375838926
REAC REAC:R-HSA-199977 ER to Golgi Anterograde Transport 0.00917204196038207 154 42 4 0.0952380952380952 0.025974025974026
REAC REAC:R-HSA-9615933 Postmitotic nuclear pore complex (NPC) reformation 0.00935974740767311 24 133 3 0.0225563909774436 0.125
REAC REAC:R-HSA-2262752 Cellular responses to stress 0.00982541328391076 546 13 4 0.307692307692308 0.00732600732600733
REAC REAC:R-HSA-8953897 Cellular responses to external stimuli 0.0104987836309529 560 13 4 0.307692307692308 0.00714285714285714
REAC REAC:R-HSA-69239 Synthesis of DNA 0.0104987836309529 120 28 3 0.107142857142857 0.025
REAC REAC:R-HSA-72202 Transport of Mature Transcript to Cytoplasm 0.0109925710456177 78 88 4 0.0454545454545455 0.0512820512820513
REAC REAC:R-HSA-69481 G2/M Checkpoints 0.0122617680010534 149 48 4 0.0833333333333333 0.0268456375838926
REAC REAC:R-HSA-69306 DNA Replication 0.0122617680010534 128 28 3 0.107142857142857 0.0234375
REAC REAC:R-HSA-983168 Antigen processing: Ubiquitination & Proteasome degradation 0.014928628899952 308 13 3 0.230769230769231 0.00974025974025974
REAC REAC:R-HSA-948021 Transport to the Golgi and subsequent modification 0.015835261322278 185 42 4 0.0952380952380952 0.0216216216216216
REAC REAC:R-HSA-5653656 Vesicle-mediated transport 0.0175028082509649 717 130 17 0.130769230769231 0.0237099023709902
REAC REAC:R-HSA-112316 Neuronal System 0.0179955662372678 400 11 3 0.272727272727273 0.0075
REAC REAC:R-HSA-165054 Rev-mediated nuclear export of HIV RNA 0.0185827261329904 32 133 3 0.0225563909774436 0.09375
REAC REAC:R-HSA-109582 Hemostasis 0.020041242989464 657 121 15 0.12396694214876 0.0228310502283105
REAC REAC:R-HSA-2559583 Cellular Senescence 0.0204593634568429 159 28 3 0.107142857142857 0.0188679245283019
REAC REAC:R-HSA-177243 Interactions of Rev with host cellular proteins 0.0214628642002969 34 133 3 0.0225563909774436 0.0882352941176471
REAC REAC:R-HSA-983169 Class I MHC mediated antigen processing & presentation 0.0227922488105514 370 13 3 0.230769230769231 0.00810810810810811
REAC REAC:R-HSA-72187 mRNA 3'-end processing 0.0267049968791791 56 88 3 0.0340909090909091 0.0535714285714286
REAC REAC:R-HSA-73856 RNA Polymerase II Transcription Termination 0.0391757698886468 65 88 3 0.0340909090909091 0.0461538461538462
REAC REAC:R-HSA-392499 Metabolism of proteins 0.0417813190214954 1961 16 7 0.4375 0.00356960734319225
REAC REAC:R-HSA-168256 Immune System 0.0441717271003204 2139 15 7 0.466666666666667 0.00327255726975222
TF TF:M03862_1 Factor: YB-1; motif: NNNNCCAATNN; match class: 1 1.34329971969452e-11 3120 107 52 0.485981308411215 0.0166666666666667
TF TF:M02106 Factor: NF-YA; motif: CRGCCAATCAGNRN 1.70826206841066e-11 1741 126 42 0.333333333333333 0.0241240666283745
TF TF:M03862 Factor: YB-1; motif: NNNNCCAATNN 1.70826206841066e-11 9198 126 101 0.801587301587302 0.0109806479669493
TF TF:M04683 Factor: NF-YA; motif: YTCTSATTGGYYRN 1.70826206841066e-11 1657 126 41 0.325396825396825 0.0247435123717562
TF TF:M10006 Factor: NF-YC; motif: NNRRCCAATCAGNR 2.10588798136148e-11 2510 117 48 0.41025641025641 0.0191235059760956
TF TF:M10005 Factor: NF-YA; motif: NYRRCCAATCAGAR 2.41832632209672e-11 2225 126 47 0.373015873015873 0.021123595505618
TF TF:M00775 Factor: NF-Y; motif: NNNNRRCCAATSR 7.13908231026849e-11 1428 126 37 0.293650793650794 0.0259103641456583
TF TF:M00287 Factor: NF-Y; motif: NNNRRCCAATSRGNNN 1.52293530160894e-10 1635 126 39 0.30952380952381 0.0238532110091743
TF TF:M07302 Factor: NF-Y; motif: RGCCAATCRGN 1.10810789999948e-09 1576 126 37 0.293650793650794 0.0234771573604061
TF TF:M03805_1 Factor: YB-1; motif: CCAMTCNGMR; match class: 1 1.22143746335417e-09 3680 107 52 0.485981308411215 0.0141304347826087
TF TF:M00209 Factor: NF-Y; motif: NCTGATTGGYTASY 1.20245032301596e-08 3776 126 57 0.452380952380952 0.0150953389830508
TF TF:M09816 Factor: NFYA; motif: RRCCAATCAGN 2.24929589418519e-08 1969 130 40 0.307692307692308 0.0203148806500762
TF TF:M09894_1 Factor: E2F-4; motif: SNGGGCGGGAANN; match class: 1 7.89810593553655e-08 13929 137 127 0.927007299270073 0.00911766817431259
TF TF:M00716 Factor: ZF5; motif: GSGCGCGR 1.84345220324393e-07 16103 137 135 0.985401459854015 0.00838353101906477
TF TF:M03805 Factor: YB-1; motif: CCAMTCNGMR 4.27678536889609e-07 10161 123 96 0.780487804878049 0.0094478889873044
TF TF:M10438_1 Factor: ZF5; motif: GGSGCGCGS; match class: 1 4.27678536889609e-07 14873 137 130 0.948905109489051 0.0087406710145902
TF TF:M07115 Factor: NF-YB; motif: NNNYNRRCCAATCAG 1.58852462416715e-06 529 136 19 0.139705882352941 0.0359168241965974
TF TF:M00687_1 Factor: alpha-CP1; motif: CAGCCAATGAG; match class: 1 1.74232091535702e-06 239 64 10 0.15625 0.0418410041841004
TF TF:M09894 Factor: E2F-4; motif: SNGGGCGGGAANN 2.84358014767835e-06 16194 137 134 0.978102189781022 0.00827466963072743
TF TF:M08526_1 Factor: E2F-3:HES-7; motif: NNNSGCGCSNNNNNCRCGYGNN; match class: 1 4.5113133453854e-06 14997 137 129 0.941605839416058 0.00860172034406881
TF TF:M11018_1 Factor: IRX-1; motif: NACRYNNNNNNNNRYGNN; match class: 1 1.77639707249248e-05 15920 137 132 0.963503649635037 0.00829145728643216
TF TF:M10438 Factor: ZF5; motif: GGSGCGCGS 2.19151058702679e-05 16228 137 133 0.970802919708029 0.00819571111658861
TF TF:M10849_1 Factor: Cdx-2; motif: NRTCGTAANNNN; match class: 1 2.19151058702679e-05 4497 133 58 0.43609022556391 0.012897487213698
TF TF:M11528 Factor: E2F-2; motif: NTTTTGGCGCCAWWWN 2.19151058702679e-05 10373 127 96 0.755905511811024 0.0092547961052733
TF TF:M00425 Factor: E2F; motif: TTTCGCGC 2.4877085641818e-05 11043 135 105 0.777777777777778 0.00950828579190437
TF TF:M11529 Factor: E2F-2; motif: GCGCGCGCNCS 2.59549463484617e-05 16263 137 133 0.970802919708029 0.00817807292627436
TF TF:M00425_1 Factor: E2F; motif: TTTCGCGC; match class: 1 6.40166954760921e-05 5355 134 64 0.477611940298507 0.0119514472455649
TF TF:M00918 Factor: E2F; motif: TTTSGCGSG 7.45504353635505e-05 5575 130 64 0.492307692307692 0.0114798206278027
TF TF:M11533 Factor: E2F-1; motif: NTTTTGGCGCCAWWWN 0.000127681019845399 13105 127 109 0.858267716535433 0.00831743609309424
TF TF:M00716_1 Factor: ZF5; motif: GSGCGCGR; match class: 1 0.000127681019845399 14106 137 122 0.89051094890511 0.00864880192825748
TF TF:M08206 Factor: E2F-3:Prrxl1; motif: SGCGCTAATTNN 0.000170709235225435 11802 95 79 0.831578947368421 0.00669378071513303
TF TF:M10006_1 Factor: NF-YC; motif: NNRRCCAATCAGNR; match class: 1 0.00017191726894731 388 18 6 0.333333333333333 0.0154639175257732
TF TF:M11531 Factor: E2F-2; motif: GCGCGCGCGYW 0.000201818523811371 13270 137 117 0.854014598540146 0.00881688018085908
TF TF:M11435 Factor: Elk-1; motif: NNCCGGAAGTN 0.000201818523811371 11728 134 106 0.791044776119403 0.00903819918144611
TF TF:M08526 Factor: E2F-3:HES-7; motif: NNNSGCGCSNNNNNCRCGYGNN 0.000201818523811371 16867 137 134 0.978102189781022 0.00794450702555285
TF TF:M00939 Factor: E2F; motif: TTTSGCGSG 0.000216860819714981 6433 135 71 0.525925925925926 0.0110368412871133
TF TF:M02107 Factor: NF-YC; motif: NRGCCAATYAGMGC 0.000248311737400029 1001 126 21 0.166666666666667 0.020979020979021
TF TF:M07250 Factor: E2F-1; motif: NNNSSCGCSAANN 0.00026305245376965 10703 135 100 0.740740740740741 0.00934317481080071
TF TF:M10578 Factor: Barhl-1; motif: NTAAACGN 0.00026305245376965 6099 110 58 0.527272727272727 0.00950975569765535
TF TF:M10005_1 Factor: NF-YA; motif: NYRRCCAATCAGAR; match class: 1 0.000272057272854541 277 126 11 0.0873015873015873 0.0397111913357401
TF TF:M10849 Factor: Cdx-2; motif: NRTCGTAANNNN 0.000294231674342072 11163 137 104 0.759124087591241 0.009316491982442
TF TF:M11018 Factor: IRX-1; motif: NACRYNNNNNNNNRYGNN 0.000309878209586745 16955 137 134 0.978102189781022 0.00790327337068711
TF TF:M11531_1 Factor: E2F-2; motif: GCGCGCGCGYW; match class: 1 0.000338424677025101 12351 137 111 0.81021897810219 0.00898712654845761
TF TF:M00919 Factor: E2F; motif: NCSCGCSAAAN 0.000356414634008526 6149 135 68 0.503703703703704 0.0110587087331273
TF TF:M04287 Factor: BARHL2; motif: NNTAAAYGNN 0.000356414634008526 4416 99 43 0.434343434343434 0.00973731884057971
TF TF:M07476_1 Factor: Lhx8; motif: TGATTG; match class: 1 0.00037701050444062 3104 110 37 0.336363636363636 0.0119201030927835
TF TF:M00287_1 Factor: NF-Y; motif: NNNRRCCAATSRGNNN; match class: 1 0.000392017504941309 184 126 9 0.0714285714285714 0.0489130434782609
TF TF:M01240 Factor: BEN; motif: CAGCGRNV 0.000399604946612855 16498 137 132 0.963503649635037 0.00800096981452297
TF TF:M02089 Factor: E2F-3; motif: GGCGGGN 0.000448656586395074 13173 130 110 0.846153846153846 0.00835041372504365
TF TF:M00209_1 Factor: NF-Y; motif: NCTGATTGGYTASY; match class: 1 0.000573155385872927 680 136 17 0.125 0.025
TF TF:M00004 Factor: c-Myb; motif: NCNRNNGRCNGTTGGKGG 0.000573155385872927 7561 117 69 0.58974358974359 0.00912577701362254
TF TF:M10793 Factor: HOXD10; motif: RGTCGTAAAAN 0.000573155385872927 73 116 6 0.0517241379310345 0.0821917808219178
TF TF:M00327_1 Factor: Pax-3; motif: NNNNNNCGTCACGSTYNNNNN; match class: 1 0.000573155385872927 6888 102 58 0.568627450980392 0.00842044134727062
TF TF:M04356 Factor: HOXC12; motif: RGTCGTAAAAN 0.000618792897627694 43 116 5 0.0431034482758621 0.116279069767442
TF TF:M09905 Factor: SAP-1; motif: NNCCGGAAGTGN 0.000618792897627694 8273 134 82 0.611940298507463 0.0099117611507313
TF TF:M04710 Factor: CHD2; motif: TCTCGCGAG 0.000645804925334225 14109 137 120 0.875912408759124 0.00850520944078248
TF TF:M02065 Factor: ER81; motif: RCCGGAARYN 0.000645804925334225 12550 134 109 0.813432835820896 0.00868525896414343
TF TF:M11002_1 Factor: LHX5; motif: NTCGTTAN; match class: 1 0.000658470205280224 114 119 7 0.0588235294117647 0.0614035087719298
TF TF:M08205_1 Factor: E2F-1:Elk-1; motif: SGCGCSNNAMCGGAAGT; match class: 1 0.000658488109801796 10438 137 98 0.715328467153285 0.0093887717953631
TF TF:M08206_1 Factor: E2F-3:Prrxl1; motif: SGCGCTAATTNN; match class: 1 0.000658488109801796 5052 137 59 0.430656934306569 0.0116785431512272
TF TF:M10809 Factor: HOXC10; motif: NGTCGTAAAAN 0.000658488109801796 77 116 6 0.0517241379310345 0.0779220779220779
TF TF:M00025 Factor: Elk-1; motif: NNNNCCGGAARTNN 0.000658488109801796 10262 134 95 0.708955223880597 0.00925745468719548
TF TF:M04826_1 Factor: p300; motif: ACNTCCG; match class: 1 0.000732124983323524 15260 107 100 0.934579439252336 0.00655307994757536
TF TF:M00427 Factor: E2F; motif: TTTSGCGS 0.000862329111804094 9485 133 89 0.669172932330827 0.00938323668950975
TF TF:M07222 Factor: NFYA; motif: AGNSYKCTGATTGGTNNR 0.000862329111804094 714 136 17 0.125 0.0238095238095238
TF TF:M11530 Factor: E2F-2; motif: NWTTTGGCGCCAWWNN 0.000989143838794853 14593 137 122 0.89051094890511 0.00836017268553416
TF TF:M04299 Factor: Dlx-1; motif: NNTAATTANN 0.000989143838794853 2524 35 15 0.428571428571429 0.00594294770206022
TF TF:M09990 Factor: c-Myb; motif: NNWGRCAGTTRN 0.00104233002190066 10698 126 92 0.73015873015873 0.0085997382688353
TF TF:M04869_1 Factor: Egr-1; motif: GCGCATGCG; match class: 1 0.00110464745588998 10253 137 96 0.700729927007299 0.00936311323515069
TF TF:M09892 Factor: E2F-1; motif: NNNNGGCGGGAARN 0.00113863211915402 13528 137 116 0.846715328467153 0.00857480780603193
TF TF:M07380 Factor: E2F-4; motif: NTTTCSCGCC 0.00122960306526579 13022 137 113 0.824817518248175 0.00867762248502534
TF TF:M10880 Factor: Alx-4; motif: NNCRTTAN 0.00128952209549122 8535 99 64 0.646464646464647 0.00749853544229643
TF TF:M04869 Factor: Egr-1; motif: GCGCATGCG 0.00133253651309351 11232 137 102 0.744525547445255 0.00908119658119658
TF TF:M08390_1 Factor: A-Myb:Elf-1; motif: NMCCGGAACCGTTA; match class: 1 0.00133253651309351 4784 110 47 0.427272727272727 0.00982441471571906
TF TF:M11603_1 Factor: TCF-1; motif: ACATCGRGRCGCTGW; match class: 1 0.00133620820943379 13184 128 107 0.8359375 0.00811589805825243
TF TF:M10727_1 Factor: HOXB8; motif: RTCRTTAN; match class: 1 0.00135068124057171 1379 29 10 0.344827586206897 0.00725163161711385
TF TF:M00004_1 Factor: c-Myb; motif: NCNRNNGRCNGTTGGKGG; match class: 1 0.00145563367048654 1883 126 28 0.222222222222222 0.0148698884758364
TF TF:M00687 Factor: alpha-CP1; motif: CAGCCAATGAG 0.00145584043150796 2326 39 15 0.384615384615385 0.00644883920894239
TF TF:M00333_1 Factor: ZF5; motif: NRNGNGCGCGCWN; match class: 1 0.00145584043150796 12401 137 109 0.795620437956204 0.00878961374082735
TF TF:M04691_1 Factor: Kaiso; motif: TCTCGCGAG; match class: 1 0.00145584043150796 10488 137 97 0.708029197080292 0.00924866514111365
TF TF:M10991_1 Factor: lmx1b; motif: CTCGTTAA; match class: 1 0.0014945517843521 91 119 6 0.0504201680672269 0.0659340659340659
TF TF:M00430 Factor: E2F-1; motif: NTTSGCGG 0.00156040010016588 8016 99 61 0.616161616161616 0.00760978043912176
TF TF:M07084 Factor: E2F-4; motif: NGGCGGGAARN 0.00164137080382733 10834 137 99 0.722627737226277 0.0091378992062027
TF TF:M09887 Factor: CREB1; motif: NRRTGACGTMA 0.00164137080382733 5419 73 37 0.506849315068493 0.00682782801254844
TF TF:M02059 Factor: ELK-1; motif: ACCGGAAGTN 0.00164137080382733 9423 134 88 0.656716417910448 0.00933885174572854
TF TF:M10575_1 Factor: Gbx2; motif: NTCRTTAN; match class: 1 0.00164137080382733 192 119 8 0.0672268907563025 0.0416666666666667
TF TF:M10956 Factor: isx; motif: NTCRTTAA 0.00169634469490874 9441 134 88 0.656716417910448 0.00932104649931151
TF TF:M08223 Factor: Elk-1:OC-2; motif: RCCGGAASCGATCGATNN 0.00169634469490874 12743 136 110 0.808823529411765 0.00863219022208271
TF TF:M00775_1 Factor: NF-Y; motif: NNNNRRCCAATSR; match class: 1 0.00169634469490874 133 126 7 0.0555555555555556 0.0526315789473684
TF TF:M09816_1 Factor: NFYA; motif: RRCCAATCAGN; match class: 1 0.00169634469490874 278 136 10 0.0735294117647059 0.0359712230215827
TF TF:M00327 Factor: Pax-3; motif: NNNNNNCGTCACGSTYNNNNN 0.00171018720400227 13318 129 108 0.837209302325581 0.00810932572458327
TF TF:M07302_1 Factor: NF-Y; motif: RGCCAATCRGN; match class: 1 0.00171018720400227 184 126 8 0.0634920634920635 0.0434782608695652
TF TF:M04683_1 Factor: NF-YA; motif: YTCTSATTGGYYRN; match class: 1 0.00172187189560379 185 126 8 0.0634920634920635 0.0432432432432432
TF TF:M03924_1 Factor: YY1; motif: NNCGCCATTNN; match class: 1 0.00172187189560379 3700 133 45 0.338345864661654 0.0121621621621622
TF TF:M00738 Factor: E2F-4:DP-1; motif: TTTSGCGC 0.00172187189560379 9812 130 88 0.676923076923077 0.00896860986547085
TF TF:M07206 Factor: E2F-1; motif: NGGGCGGGARV 0.00175385978963177 14575 137 121 0.883211678832117 0.00830188679245283
TF TF:M00920 Factor: E2F; motif: NKCGCGCSAAAN 0.00175744286320218 5663 126 58 0.46031746031746 0.0102419212431573
TF TF:M12151 Factor: Sp1; motif: NWRGCCMCGCCCMCN 0.00176184284305924 6821 128 67 0.5234375 0.00982260665591556
TF TF:M11529_1 Factor: E2F-2; motif: GCGCGCGCNCS; match class: 1 0.00196650604219148 14473 128 113 0.8828125 0.00780764181579493
TF TF:M10695_1 Factor: HOXA6; motif: RTCRTTAN; match class: 1 0.00196650604219148 1493 29 10 0.344827586206897 0.00669792364367046
TF TF:M00803 Factor: E2F; motif: GGCGSG 0.00196650604219148 13190 137 113 0.824817518248175 0.00856709628506444
TF TF:M04109_1 Factor: RUNX3; motif: NRACCGCAAACCGCAN; match class: 1 0.00196650604219148 3878 64 27 0.421875 0.00696235172769469
TF TF:M08913 Factor: FLI-1; motif: NAYTTCCGGT 0.00196650604219148 8322 134 80 0.597014925373134 0.00961307378034126
TF TF:M00185 Factor: NF-Y; motif: TRRCCAATSRN 0.00196650604219148 870 112 16 0.142857142857143 0.0183908045977011
TF TF:M04748_1 Factor: GABP-alpha; motif: AACCGGAAR; match class: 1 0.00196650604219148 10368 133 93 0.699248120300752 0.00896990740740741
TF TF:M10999_1 Factor: LIM-1; motif: NNCGTTAN; match class: 1 0.00196650604219148 1266 122 21 0.172131147540984 0.0165876777251185
TF TF:M08205 Factor: E2F-1:Elk-1; motif: SGCGCSNNAMCGGAAGT 0.00196650604219148 14429 137 120 0.875912408759124 0.00831658465590131
TF TF:M10747_1 Factor: GSH2; motif: NTCRTTAN; match class: 1 0.00204222101849808 335 119 10 0.0840336134453782 0.0298507462686567
TF TF:M10936_1 Factor: CHX10; motif: NTCRTTAN; match class: 1 0.00204222101849808 335 119 10 0.0840336134453782 0.0298507462686567
TF TF:M10945_1 Factor: VSX1; motif: NTCRTTAN; match class: 1 0.00204222101849808 335 119 10 0.0840336134453782 0.0298507462686567
TF TF:M10942_1 Factor: VSX1; motif: NTCRTTAN; match class: 1 0.00204222101849808 335 119 10 0.0840336134453782 0.0298507462686567
TF TF:M02107_1 Factor: NF-YC; motif: NRGCCAATYAGMGC; match class: 1 0.00204222101849808 58 126 5 0.0396825396825397 0.0862068965517241
TF TF:M10563_1 Factor: Msx-1; motif: NTCRTTAN; match class: 1 0.00204222101849808 335 119 10 0.0840336134453782 0.0298507462686567
TF TF:M10939_1 Factor: CHX10; motif: NTCRTTAN; match class: 1 0.00204222101849808 335 119 10 0.0840336134453782 0.0298507462686567
TF TF:M10874_1 Factor: alx3; motif: NKCRTTAN; match class: 1 0.00204222101849808 335 119 10 0.0840336134453782 0.0298507462686567
TF TF:M11005 Factor: LHX4; motif: NNCRTTAN 0.0020891454605832 10614 134 95 0.708955223880597 0.00895044281138119
TF TF:M02102 Factor: NRF-1; motif: YGCGCMTGCGC 0.00218685112497728 2020 136 30 0.220588235294118 0.0148514851485149
TF TF:M10821 Factor: HOXA11; motif: GGTCGTAAAAN 0.00222831269597388 107 116 6 0.0517241379310345 0.0560747663551402
TF TF:M00426 Factor: E2F; motif: TTTSGCGS 0.00237183201238375 11885 133 102 0.766917293233083 0.00858224652923854
TF TF:M10887_1 Factor: PRX-2; motif: NNCRTTAN; match class: 1 0.00237183201238375 1198 122 20 0.163934426229508 0.01669449081803
TF TF:M07052 Factor: NRF-1; motif: GCGCMTGCGCN 0.00237183201238375 2130 50 16 0.32 0.00751173708920188
TF TF:M10885_1 Factor: PRX-2; motif: NKCGTTAN; match class: 1 0.00237183201238375 1198 122 20 0.163934426229508 0.01669449081803
TF TF:M11530_1 Factor: E2F-2; motif: NWTTTGGCGCCAWWNN; match class: 1 0.00242783135861107 13449 129 108 0.837209302325581 0.00803033682801695
TF TF:M08959_1 Factor: PAX-7; motif: NASCGTRACKAAT; match class: 1 0.00242783135861107 3856 69 28 0.405797101449275 0.00726141078838174
TF TF:M01337 Factor: HOXA3; motif: NNNNRNTAATTARY 0.00255020176814669 15857 137 127 0.927007299270073 0.00800908116289336
TF TF:M08457 Factor: ER71:SREBP-2; motif: NTSACGTGACGGAARY 0.00310000235600534 12052 135 104 0.77037037037037 0.0086292731496847
TF TF:M08377 Factor: meis1:Elf-1; motif: NTGCCGGAAGTN 0.00318518127629847 11275 115 86 0.747826086956522 0.00762749445676275
TF TF:M00431 Factor: E2F-1; motif: TTTSGCGS 0.00318518127629847 7257 135 72 0.533333333333333 0.00992145514675486
TF TF:M05544 Factor: BCL-11A; motif: CSTAMGGA 0.00322486143746813 409 126 11 0.0873015873015873 0.0268948655256724
TF TF:M10819 Factor: HOXA11; motif: NGTCGTAAAAN 0.0032924646347044 72 116 5 0.0431034482758621 0.0694444444444444
TF TF:M01299 Factor: MECP2; motif: CCGGNNTTWA 0.00331620908096536 5228 84 39 0.464285714285714 0.00745983167559296
TF TF:M02071 Factor: ETV7; motif: NCCGGAANNN 0.00331620908096536 10116 134 91 0.67910447761194 0.00899565045472519
TF TF:M08890 Factor: MYB; motif: NNAACTGN 0.00334775362207507 1355 55 13 0.236363636363636 0.00959409594095941
TF TF:M10686_1 Factor: HOXB7; motif: GTCRTTAN; match class: 1 0.00340169992044496 477 43 7 0.162790697674419 0.0146750524109015
TF TF:M02056 Factor: ELF4; motif: NCCGGAARTN 0.00355427318403707 5332 134 57 0.425373134328358 0.0106901725431358
TF TF:M01281_1 Factor: NFATc2; motif: GGAAAA; match class: 1 0.00355872943326297 11109 64 51 0.796875 0.00459087226573049
TF TF:M01886_1 Factor: NFATc3; motif: GGAAAA; match class: 1 0.00355872943326297 11109 64 51 0.796875 0.00459087226573049
TF TF:M03555_1 Factor: NFATc2; motif: GGAAAA; match class: 1 0.00355872943326297 11109 64 51 0.796875 0.00459087226573049
TF TF:M08768 Factor: HOXA10; motif: RGTMGTAAAAN 0.00356715629266003 450 117 11 0.094017094017094 0.0244444444444444
TF TF:M10827 Factor: HOXC12; motif: NGTCGTAAAAN 0.00382810134794951 16 107 3 0.0280373831775701 0.1875
TF TF:M11541 Factor: Foxn2; motif: NNGCGTCNNNNNGACGCNN 0.00402559342133907 5751 107 50 0.467289719626168 0.00869414014953921
TF TF:M11882 Factor: pax-6; motif: NYACGCNYSANYGMNCN 0.0044574590667284 15490 120 110 0.916666666666667 0.00710135571336346
TF TF:M10803 Factor: HOXC10; motif: NGTCGTAAANN 0.00450146243999565 17 107 3 0.0280373831775701 0.176470588235294
TF TF:M10807 Factor: HOXC10; motif: NGTCGTAAAAN 0.00450146243999565 17 107 3 0.0280373831775701 0.176470588235294
TF TF:M10018 Factor: NRF-1; motif: CNSTGCGCATGCGCNNS 0.00458297018469733 1816 136 27 0.198529411764706 0.0148678414096916
TF TF:M10823 Factor: HOXD11; motif: NRTCGTAAANNKTWAY 0.00468354932878309 127 116 6 0.0517241379310345 0.047244094488189
TF TF:M10861_1 Factor: En-1; motif: VTCRTTAN; match class: 1 0.00468712283484177 459 119 11 0.092436974789916 0.0239651416122004
TF TF:M10755_1 Factor: hoxd1; motif: NTCRTTAN; match class: 1 0.0048411350866079 310 119 9 0.0756302521008403 0.0290322580645161
TF TF:M00333 Factor: ZF5; motif: NRNGNGCGCGCWN 0.0048411350866079 15072 120 108 0.9 0.0071656050955414
TF TF:M10880_1 Factor: Alx-4; motif: NNCRTTAN; match class: 1 0.00514424530455917 2683 131 34 0.259541984732824 0.0126723816623183
TF TF:M11231 Factor: CREBL1; motif: GRTGACGTCAYC 0.00516430277529082 1057 73 13 0.178082191780822 0.0122989593188269
TF TF:M11541_1 Factor: Foxn2; motif: NNGCGTCNNNNNGACGCNN; match class: 1 0.00517907323939231 5493 107 48 0.448598130841121 0.00873839432004369
TF TF:M08982_1 Factor: YY1; motif: NAANATGGCGNNN; match class: 1 0.00546555034905796 1662 89 19 0.213483146067416 0.0114320096269555
TF TF:M07095 Factor: FOXP1; motif: NNNANGTAAACAAAN 0.00546555034905796 341 136 10 0.0735294117647059 0.0293255131964809
TF TF:M00430_1 Factor: E2F-1; motif: NTTSGCGG; match class: 1 0.00565547977170409 2524 134 33 0.246268656716418 0.0130744849445325
TF TF:M10781 Factor: HOXC9; motif: GTCGTAAAAN 0.00571102448525756 84 116 5 0.0431034482758621 0.0595238095238095
TF TF:M06948 Factor: Sp2; motif: TGGGCGCGCCCA 0.00571102448525756 8864 129 79 0.612403100775194 0.00891245487364621
TF TF:M08930_1 Factor: JUND:FRA-1; motif: RTGACGTMAY; match class: 1 0.00581216202365288 1607 100 20 0.2 0.0124455507156192
TF TF:M02090 Factor: E2F-4; motif: GCGGGAAANA 0.0059120720468283 11966 136 103 0.757352941176471 0.00860772187865619
TF TF:M03958_1 Factor: E2F2; motif: AAAAATGGCGCCAAAAWG; match class: 1 0.00607548086638557 4181 127 45 0.354330708661417 0.0107629753647453
TF TF:M11396 Factor: Erg; motif: NACCGGAARTN 0.00633752853099948 10765 134 94 0.701492537313433 0.00873200185787274
TF TF:M10625 Factor: Nkx3-2; motif: NTCGTTAN 0.00671175687321246 6062 133 61 0.458646616541353 0.0100626855823161
TF TF:M11609 Factor: LEF-1; motif: ASATCAAAG 0.00688608918764187 3078 22 11 0.5 0.00357374918778428
TF TF:M11257 Factor: AIBZIP; motif: NRTGACGTCAYN 0.0071937804664823 981 71 12 0.169014084507042 0.0122324159021407
TF TF:M04810 Factor: USF2; motif: AAGTCACG 0.00723474063671487 5496 137 58 0.423357664233577 0.0105531295487627
TF TF:M07476 Factor: Lhx8; motif: TGATTG 0.00723474063671487 9096 127 79 0.622047244094488 0.00868513632365875
TF TF:M04448 Factor: VENTX; motif: ANCGATTAR 0.00723474063671487 419 116 10 0.0862068965517241 0.0238663484486874
TF TF:M01661 Factor: hbp1; motif: BTCAATSAR 0.00727076172693788 547 58 8 0.137931034482759 0.0146252285191956
TF TF:M00516 Factor: E2F-1; motif: TTTSGCGCGMNR 0.00728261774589432 6904 126 64 0.507936507936508 0.00926998841251448
TF TF:M04059 Factor: NRF-1; motif: YGCGCATGCGCN 0.0074069139649434 1471 137 23 0.167883211678832 0.0156356220258328
TF TF:M01820_1 Factor: CREM; motif: TGACGTCASYN; match class: 1 0.0074069139649434 1879 95 21 0.221052631578947 0.0111761575306014
TF TF:M08390 Factor: A-Myb:Elf-1; motif: NMCCGGAACCGTTA 0.0074069139649434 11072 133 95 0.714285714285714 0.00858020231213873
TF TF:M10977_1 Factor: LHX9; motif: NTCGTTAN; match class: 1 0.00749143930807834 48 119 4 0.0336134453781513 0.0833333333333333
TF TF:M10727 Factor: HOXB8; motif: RTCRTTAN 0.00756973976882745 6289 58 32 0.551724137931034 0.00508824932421689
TF TF:M00740 Factor: Rb:E2F-1:DP-1; motif: TTTSGCGC 0.00769706040198476 10427 130 89 0.684615384615385 0.0085355327515105
TF TF:M04823 Factor: E2F-4; motif: NNTTCCCGCCNN 0.00776832796229521 12747 137 108 0.788321167883212 0.00847258178394916
TF TF:M00179_1 Factor: ATF2; motif: VGTGACGTMACN; match class: 1 0.00776832796229521 1778 73 17 0.232876712328767 0.00956130483689539
TF TF:M00671 Factor: TCF-4; motif: SCTTTGAW 0.00816915048727303 3621 75 27 0.36 0.00745650372825186
TF TF:M03922 Factor: SP4; motif: NWRGCCACGCCCMCTYN 0.00834224582681201 6046 124 57 0.459677419354839 0.00942772080714522
TF TF:M10683_1 Factor: HOXB7; motif: GTCRTTAN; match class: 1 0.00834224582681201 110 99 5 0.0505050505050505 0.0454545454545455
TF TF:M04341 Factor: HOXA13; motif: CYAATAAAAN 0.00834224582681201 951 75 12 0.16 0.0126182965299685
TF TF:M10948 Factor: rax; motif: NNCRTTAN 0.00858699912642205 11816 134 100 0.746268656716418 0.00846310088016249
TF TF:M00740_1 Factor: Rb:E2F-1:DP-1; motif: TTTSGCGC; match class: 1 0.00858699912642205 4583 129 48 0.372093023255814 0.0104734889810168
TF TF:M11601_1 Factor: TCF-1; motif: ACATCGRGRCGCTGW; match class: 1 0.00906868606263638 11053 101 74 0.732673267326733 0.00669501492807383
TF TF:M10758_1 Factor: HOXB1; motif: NTCRTTAN; match class: 1 0.00934303545832153 275 119 8 0.0672268907563025 0.0290909090909091
TF TF:M04362 Factor: HOXD12; motif: RGTCGTAAAAN 0.0094468225206099 151 116 6 0.0517241379310345 0.0397350993377483
TF TF:M10789 Factor: HOXD10; motif: RTCGTAAANN 0.00968431908959412 152 116 6 0.0517241379310345 0.0394736842105263
TF TF:M10779 Factor: HOXC9; motif: GTCGTAAAAN 0.00968431908959412 152 116 6 0.0517241379310345 0.0394736842105263
TF TF:M07052_1 Factor: NRF-1; motif: GCGCMTGCGCN; match class: 1 0.00976387404456103 734 71 10 0.140845070422535 0.0136239782016349
TF TF:M11540 Factor: Foxn2; motif: NGCATCRNNNYGATGCN 0.00977318926655143 397 129 10 0.0775193798449612 0.0251889168765743
TF TF:M10104_1 Factor: YY1; motif: CAARATGGCGGC; match class: 1 0.0101949745468812 1138 65 12 0.184615384615385 0.0105448154657293
TF TF:M00338 Factor: ATF; motif: NTGACGTCANYS 0.0101949745468812 3798 73 27 0.36986301369863 0.00710900473933649
TF TF:M09966 Factor: Kaiso; motif: SARNYCTCGCGAGAN 0.0102240109971444 2356 96 24 0.25 0.0101867572156197
TF TF:M04517 Factor: E2F2; motif: AAAATGGCGCCATTTT 0.0102366225589805 9190 47 34 0.723404255319149 0.00369967355821545
TF TF:M11220_1 Factor: CREB1; motif: NNTGACGTCANN; match class: 1 0.0104591852389271 1713 71 16 0.225352112676056 0.00934033858727379
TF TF:M10625_1 Factor: Nkx3-2; motif: NTCGTTAN; match class: 1 0.0106585421676285 1314 119 19 0.159663865546218 0.0144596651445967
TF TF:M11654 Factor: HSF1; motif: RGAANRTTCYRGAAN 0.0106585421676285 1353 3 3 1 0.00221729490022173
TF TF:M00178_1 Factor: CREB; motif: NSTGACGTMANN; match class: 1 0.010845946582207 1522 72 15 0.208333333333333 0.00985545335085414
TF TF:M09636 Factor: MAZ; motif: GGGMGGGGSSGGGGGGGGGGGG 0.010845946582207 16244 130 121 0.930769230769231 0.00744890421078552
TF TF:M10854 Factor: Cdx-4; motif: SGTCGTAAANN 0.0108768507283474 61 107 4 0.0373831775700935 0.0655737704918033
TF TF:M03560_1 Factor: PMX1; motif: TAATHA; match class: 1 0.0108768507283474 10273 75 54 0.72 0.00525649761510756
TF TF:M11220 Factor: CREB1; motif: NNTGACGTCANN 0.0109226009194454 1725 71 16 0.225352112676056 0.00927536231884058
TF TF:M09600_1 Factor: CREB1; motif: TKACGTCAYNN; match class: 1 0.0109562511730597 1552 94 18 0.191489361702128 0.0115979381443299
TF TF:M02279 Factor: CREB1; motif: TGACGTCA 0.0111909378424305 1731 71 16 0.225352112676056 0.00924321201617562
TF TF:M11005_1 Factor: LHX4; motif: NNCRTTAN; match class: 1 0.0111909378424305 4203 127 44 0.346456692913386 0.0104687128241732
TF TF:M10956_1 Factor: isx; motif: NTCRTTAA; match class: 1 0.0112548989846351 3336 126 37 0.293650793650794 0.0110911270983213
TF TF:M01078 Factor: c-Ets-1; motif: NNNRCCGGAWRYNNNN 0.0112654742318989 7544 134 71 0.529850746268657 0.00941145281018028
TF TF:M04106_1 Factor: RUNX2; motif: NRACCGCAAACCGCAN; match class: 1 0.0116364852966829 8372 26 20 0.769230769230769 0.00238891543239369
TF TF:M10591 Factor: BSX; motif: NNCGTTAN 0.0116364852966829 7760 133 72 0.541353383458647 0.00927835051546392
TF TF:M04694 Factor: NRF-1; motif: CNCTGCGCATGCGC 0.0116385794075878 1548 50 12 0.24 0.00775193798449612
TF TF:M08525 Factor: E2F-1:HES-7; motif: GGCRCGTGSYNNWNGGCGCSM 0.0116385794075878 17065 137 131 0.956204379562044 0.0076765309112218
TF TF:M10825 Factor: HOXC12; motif: NRTCGTAAAAN 0.0116385794075878 161 116 6 0.0517241379310345 0.0372670807453416
TF TF:M04555 Factor: SRY; motif: AACAATANCATTGTT 0.0116385794075878 7098 137 69 0.503649635036496 0.00972104818258664
TF TF:M06246 Factor: ZNF177; motif: NRWTGAAGAGCA 0.0116385794075878 174 39 4 0.102564102564103 0.0229885057471264
TF TF:M04691 Factor: Kaiso; motif: TCTCGCGAG 0.0118912080292798 15113 137 121 0.883211678832117 0.00800635214715808
TF TF:M12163 Factor: KLF3; motif: GRCCRCGCCCN 0.0120270948803871 733 18 5 0.277777777777778 0.00682128240109141
TF TF:M08779_1 Factor: PXR; motif: AGTTCANNSAGTTC; match class: 1 0.012070917984417 455 28 5 0.178571428571429 0.010989010989011
TF TF:M11797 Factor: NR1B1; motif: NRAGGTCANG 0.012070917984417 1948 8 5 0.625 0.00256673511293634
TF TF:M10723_1 Factor: HOXD8; motif: RTCRTTAN; match class: 1 0.0121984644126265 636 43 7 0.162790697674419 0.0110062893081761
TF TF:M10785_1 Factor: hoxa9; motif: RTCGTWANNN; match class: 1 0.0124134534372179 1160 57 11 0.192982456140351 0.00948275862068966
TF TF:M11578 Factor: foxl2; motif: NACGTMAACAN 0.0127168578369737 5451 133 55 0.413533834586466 0.0100898917629793
TF TF:M11430 Factor: PEA3; motif: NACCGGAAGTN 0.0127259375786771 10865 137 95 0.693430656934307 0.0087436723423838
TF TF:M02220 Factor: HNF4A; motif: RGGNCAAAGKYCA 0.0127649243708 1679 18 7 0.388888888888889 0.00416914830256105
TF TF:M05386 Factor: KLF17; motif: NGGGCGG 0.0127649243708 7900 100 57 0.57 0.00721518987341772
TF TF:M05499 Factor: LKLF; motif: NGGGCGG 0.0127649243708 7900 100 57 0.57 0.00721518987341772
TF TF:M01861_1 Factor: ATF-1; motif: TNACGTCAN; match class: 1 0.0129503580305895 1896 73 17 0.232876712328767 0.0089662447257384
TF TF:M03950 Factor: CDP; motif: ATCGATNNNNNATCRAT 0.0132919661740779 4197 136 46 0.338235294117647 0.0109602096735764
TF TF:M04518 Factor: E2F-4; motif: AATGGCGCCAAA 0.0132919661740779 5521 126 53 0.420634920634921 0.009599710197428
TF TF:M02066 Factor: PEA3; motif: RCCGGAAGYN 0.0133468145831006 7045 134 67 0.5 0.00951029098651526
TF TF:M12002_1 Factor: AML2; motif: CWAACCGCAAAAACCGCARN; match class: 1 0.0133563768429103 2361 76 20 0.263157894736842 0.00847098686997035
TF TF:M04042_1 Factor: MYBL1; motif: ACCGTTAAACNG; match class: 1 0.0136322818945859 95 32 3 0.09375 0.0315789473684211
TF TF:M07312 Factor: ATF-2; motif: NNTGACGTCAN 0.0136641851920516 3483 73 25 0.342465753424658 0.00717772035601493
TF TF:M02106_1 Factor: NF-YA; motif: CRGCCAATCAGNRN; match class: 1 0.013780567351737 217 126 7 0.0555555555555556 0.032258064516129
TF TF:M08959 Factor: PAX-7; motif: NASCGTRACKAAT 0.0141305575441971 10532 57 43 0.754385964912281 0.00408279529054311
TF TF:M11656 Factor: HSF1; motif: RGAANRTTCYRGAAN 0.0141476958882746 2033 5 4 0.8 0.00196753566158387
TF TF:M11228_1 Factor: ATF-6; motif: GRTGACGTCAYC; match class: 1 0.0141476958882746 2102 73 18 0.246575342465753 0.00856327307326356
TF TF:M04826 Factor: p300; motif: ACNTCCG 0.0141750676906182 17806 137 134 0.978102189781022 0.00752555318431989
TF TF:M03814 Factor: BTEB2; motif: GNAGGGGGNGGGSSNN 0.0144736750043895 5124 12 9 0.75 0.00175644028103044
TF TF:M00695 Factor: ETF; motif: GVGGMGG 0.0144829423984555 10430 96 67 0.697916666666667 0.00642377756471716
TF TF:M10768 Factor: HOXB9; motif: GTCGTAAANY 0.0145696363549948 172 116 6 0.0517241379310345 0.0348837209302326
TF TF:M06060 Factor: ZNF729; motif: GTTGAGAAGA 0.0145696363549948 88 84 4 0.0476190476190476 0.0454545454545455
TF TF:M02102_1 Factor: NRF-1; motif: YGCGCMTGCGC; match class: 1 0.0145696363549948 654 71 9 0.126760563380282 0.0137614678899083
TF TF:M10591_1 Factor: BSX; motif: NNCGTTAN; match class: 1 0.0145820087202911 2259 122 27 0.221311475409836 0.0119521912350598
TF TF:M00427_1 Factor: E2F; motif: TTTSGCGS; match class: 1 0.0147814981547996 3831 129 41 0.317829457364341 0.0107021665361524
TF TF:M11434 Factor: Elk-1; motif: NRSCGGAAGNN 0.0150435324130234 8219 134 75 0.559701492537313 0.00912519771261711
TF TF:M11611 Factor: LEF-1; motif: ASATCAAAG 0.0151867202629116 3517 22 11 0.5 0.00312766562411146
TF TF:M11228 Factor: ATF-6; motif: GRTGACGTCAYC 0.0151867202629116 2123 73 18 0.246575342465753 0.00847856806406029
TF TF:M00917_1 Factor: CREB; motif: CNNTGACGTMA; match class: 1 0.0152998509467678 1590 88 17 0.193181818181818 0.0106918238993711
TF TF:M11431_1 Factor: PEA3; motif: NTCGTAAATGCA; match class: 1 0.0158373311180619 4298 30 15 0.5 0.00348999534667287
TF TF:M09600 Factor: CREB1; motif: TKACGTCAYNN 0.0160537835982569 5324 73 33 0.452054794520548 0.00619834710743802
TF TF:M01240_1 Factor: BEN; motif: CAGCGRNV; match class: 1 0.0160654762971833 13227 50 44 0.88 0.00332652906932789
TF TF:M08215 Factor: Elk-1:EVX1; motif: NNCGGWAATNNYMATTA 0.0160654762971833 6557 124 59 0.475806451612903 0.00899801738599969
TF TF:M09592 Factor: ATF-1; motif: NRTGACGTMAN 0.0160654762971833 4411 73 29 0.397260273972603 0.0065744729086375
TF TF:M07380_1 Factor: E2F-4; motif: NTTTCSCGCC; match class: 1 0.0160937471702894 7965 136 74 0.544117647058823 0.00929064657878217
TF TF:M10774 Factor: hoxd9; motif: GTCGTAAAAN 0.0167787030991041 248 116 7 0.0603448275862069 0.0282258064516129
TF TF:M10811 Factor: HOXC11; motif: NGTCGTAAANN 0.0167787030991041 179 116 6 0.0517241379310345 0.0335195530726257
TF TF:M10729_1 Factor: HOXC-8; motif: RTCRTTAN; match class: 1 0.0167787030991041 548 39 6 0.153846153846154 0.0109489051094891
TF TF:M10999 Factor: LIM-1; motif: NNCGTTAN 0.0167787030991041 5894 134 58 0.432835820895522 0.00984051577875806
TF TF:M11586 Factor: foxj3; motif: ACGTAAACAN 0.0167956895130657 1252 132 19 0.143939393939394 0.0151757188498403
TF TF:M09990_1 Factor: c-Myb; motif: NNWGRCAGTTRN; match class: 1 0.0169327994900561 3933 85 30 0.352941176470588 0.007627765064836
TF TF:M11008_1 Factor: LHX4; motif: NTCRTTAN; match class: 1 0.0169923649089308 1626 119 21 0.176470588235294 0.0129151291512915
TF TF:M04610 Factor: CDP; motif: NNNNWGWYMAATR 0.0171166475690565 4564 68 28 0.411764705882353 0.00613496932515337
TF TF:M08457_1 Factor: ER71:SREBP-2; motif: NTSACGTGACGGAARY; match class: 1 0.0171166475690565 5591 135 56 0.414814814814815 0.0100160972992309
TF TF:M01660 Factor: GABP-alpha; motif: CTTCCK 0.0171868258430242 11116 134 94 0.701492537313433 0.00845627923713566
TF TF:M11975_1 Factor: RFX7; motif: SGTTGCTRN; match class: 1 0.0173002999163641 186 43 4 0.0930232558139535 0.021505376344086
TF TF:M00428 Factor: E2F-1; motif: NKTSSCGC 0.0176604788324816 8947 129 77 0.596899224806202 0.00860623672739466
TF TF:M03977 Factor: ETS1; motif: ACCGGAARYN 0.0180798042927725 10512 134 90 0.671641791044776 0.00856164383561644
TF TF:M08020 Factor: YY2; motif: NNCCGCCATTW 0.0181019326730339 1331 88 15 0.170454545454545 0.0112697220135237
TF TF:M04111 Factor: RUNX3; motif: WAACCRCAAA 0.0181019326730339 485 30 5 0.166666666666667 0.0103092783505155
TF TF:M09866 Factor: ATF-1; motif: NNRTGACGYMA 0.0181019326730339 3162 73 23 0.315068493150685 0.00727387729285262
TF TF:M02027 Factor: PARP; motif: TTTCYN 0.0182733223222909 16377 111 104 0.936936936936937 0.00635036942052879
TF TF:M10665_1 Factor: LBX2; motif: CTYRTTAA; match class: 1 0.0182733223222909 33 108 3 0.0277777777777778 0.0909090909090909
TF TF:M11424 Factor: Erm; motif: NNSCGGAWGYN 0.0182733223222909 8149 134 74 0.552238805970149 0.00908086881825991
TF TF:M10662_1 Factor: LBX2; motif: CTCRTTAA; match class: 1 0.0182733223222909 33 108 3 0.0277777777777778 0.0909090909090909
TF TF:M08923 Factor: JUNB:FRA-2; motif: NRTGASTCAT 0.0182733223222909 2927 19 9 0.473684210526316 0.00307482063546293
TF TF:M08947_1 Factor: C-FOS; motif: NNNKATGACGTCATNNN; match class: 1 0.0183782546056041 2723 74 21 0.283783783783784 0.0077120822622108
TF TF:M11888 Factor: Pax-4a; motif: NTYACGCWTSANYGCNYN 0.018389329641493 753 107 12 0.11214953271028 0.0159362549800797
TF TF:M00773 Factor: c-MYB; motif: NNNGNCAGTTN 0.0183899521469886 3451 84 27 0.321428571428571 0.00782381918284555
TF TF:M02070 Factor: TEL1; motif: CNCGGAANNN 0.0185091009536209 10837 134 92 0.686567164179104 0.00848943434529851
TF TF:M02069 Factor: Erm; motif: ACCGGAAGTN 0.0186190042790853 6892 110 55 0.5 0.00798026697620429
TF TF:M07124 Factor: AML3; motif: KNKNTYTGTGGTTTK 0.0190528639756476 1440 7 4 0.571428571428571 0.00277777777777778
TF TF:M09813 Factor: MYB; motif: NNCAACTGNN 0.0194003729697195 5545 25 15 0.6 0.00270513976555455
TF TF:M10877_1 Factor: alx3; motif: NNCRTTAN; match class: 1 0.0195519766320411 587 119 11 0.092436974789916 0.0187393526405451
TF TF:M03988 Factor: FLI1; motif: ACCGGAARTN 0.0196381518152398 8318 134 75 0.559701492537313 0.00901659052656889
TF TF:M04696_1 Factor: YY1; motif: GCCGCCATNTTGNNNNNGGNCN; match class: 1 0.0197576504084276 1973 94 20 0.212765957446809 0.010136847440446
TF TF:M10877 Factor: alx3; motif: NNCRTTAN 0.0197576504084276 4165 133 44 0.330827067669173 0.0105642256902761
TF TF:M11438_1 Factor: SAP-1; motif: NTCGTAAATGCN; match class: 1 0.0197666439270686 1191 27 7 0.259259259259259 0.00587741393786734
TF TF:M11535 Factor: E2F-4; motif: TTTTGGCGCCAWWN 0.0197744941466 10884 137 94 0.686131386861314 0.00863653068724734
TF TF:M07090_1 Factor: c-Fos; motif: NNTGASTCATN; match class: 1 0.0197744941466 1726 10 5 0.5 0.00289687137891078
TF TF:M09641 Factor: NRF-1; motif: SYGCGCMTGCGCRNNGSN 0.0198691525660483 3222 136 37 0.272058823529412 0.0114835505896958
TF TF:M01452 Factor: HOXA5; motif: ANGNTAATTANCNNAN 0.0199726042891209 3709 35 15 0.428571428571429 0.00404421677001887
TF TF:M09641_1 Factor: NRF-1; motif: SYGCGCMTGCGCRNNGSN; match class: 1 0.0202176162506074 991 119 15 0.126050420168067 0.0151362260343088
TF TF:M02019 Factor: LEF-1; motif: WCAAAGN 0.0204751952329275 4655 29 15 0.517241379310345 0.00322234156820623
TF TF:M11604 Factor: LEF-1; motif: ASATCAAAG 0.0204751952329275 3714 22 11 0.5 0.00296176628971459
TF TF:M03794 Factor: LEF-1; motif: WCAAAGN 0.0204751952329275 4655 29 15 0.517241379310345 0.00322234156820623
TF TF:M00432 Factor: TTF1; motif: ASTCAAGTRK 0.0204751952329275 5394 21 13 0.619047619047619 0.00241008527994067
TF TF:M00041 Factor: ATF2:c-Jun; motif: TGACGTYA 0.0204751952329275 4294 73 28 0.383561643835616 0.00652072659524919
TF TF:M00916_1 Factor: CREB; motif: NNTKACGTCANNNS; match class: 1 0.0205270665312347 1692 94 18 0.191489361702128 0.0106382978723404
TF TF:M01362_1 Factor: CART1; motif: NGNNYTAATTARTNNNN; match class: 1 0.0208062151862892 3461 17 9 0.529411764705882 0.00260040450736781
TF TF:M01400_1 Factor: Dlx-3; motif: NNNNNATAATTACMNNN; match class: 1 0.0208062151862892 944 34 7 0.205882352941176 0.00741525423728814
TF TF:M00769 Factor: AML; motif: NNGKNTGTGGTTWNC 0.0208062151862892 1501 7 4 0.571428571428571 0.00266489007328448
TF TF:M10885 Factor: PRX-2; motif: NKCGTTAN 0.0211828743666042 5715 134 56 0.417910447761194 0.00979877515310586
TF TF:M10887 Factor: PRX-2; motif: NNCRTTAN 0.0211828743666042 5715 134 56 0.417910447761194 0.00979877515310586
TF TF:M09780 Factor: PBX2; motif: NTGATTGACAGN 0.0213319674896448 496 101 9 0.0891089108910891 0.0181451612903226
TF TF:M01862 Factor: ATF-2; motif: NNNTGACGTNAN 0.0213798554902981 3230 73 23 0.315068493150685 0.00712074303405573
TF TF:M00426_1 Factor: E2F; motif: TTTSGCGS; match class: 1 0.0216974241134122 5830 129 55 0.426356589147287 0.00943396226415094
TF TF:M01820 Factor: CREM; motif: TGACGTCASYN 0.0216974241134122 6303 97 46 0.474226804123711 0.00729811201015389
TF TF:M00918_1 Factor: E2F; motif: TTTSGCGSG; match class: 1 0.0216974241134122 1255 126 18 0.142857142857143 0.0143426294820717
TF TF:M11150 Factor: msc; motif: NRACAGCTGTYN 0.0216974241134122 400 101 8 0.0792079207920792 0.02
TF TF:M07102_1 Factor: c-Jun; motif: NNNNRRTGASTCAN; match class: 1 0.0216974241134122 3047 19 9 0.473684210526316 0.00295372497538563
TF TF:M09866_1 Factor: ATF-1; motif: NNRTGACGYMA; match class: 1 0.0221078176001437 955 88 12 0.136363636363636 0.012565445026178
TF TF:M00178 Factor: CREB; motif: NSTGACGTMANN 0.0228755141008953 5255 73 32 0.438356164383562 0.00608943862987631
TF TF:M10948_1 Factor: rax; motif: NNCRTTAN; match class: 1 0.0228755141008953 5245 127 50 0.393700787401575 0.00953288846520496
TF TF:M01337_1 Factor: HOXA3; motif: NNNNRNTAATTARY; match class: 1 0.0230670562957044 12033 64 51 0.796875 0.00423834455248068
TF TF:M08207 Factor: E2F-3:TBR2; motif: ANGTGYKANGGCGCSTTNNCRNNT 0.0232018359158491 17055 137 130 0.948905109489051 0.00762239812371739
TF TF:M04360_1 Factor: HOXD11; motif: NNYMATAAAA; match class: 1 0.0232018359158491 1048 50 9 0.18 0.00858778625954199
TF TF:M10578_1 Factor: Barhl-1; motif: NTAAACGN; match class: 1 0.0233792778273157 1391 62 12 0.193548387096774 0.00862688713156003
TF TF:M12275_1 Factor: YY1; motif: NGCCGCCATYTTGN; match class: 1 0.0235028698699402 1600 109 19 0.174311926605505 0.011875
TF TF:M00017 Factor: ATF; motif: CNSTGACGTNNNYC 0.0235082618069454 7226 73 40 0.547945205479452 0.00553556601162469
TF TF:M04320_1 Factor: EVX1; motif: NNTNATTANN; match class: 1 0.0235219592486791 1875 35 10 0.285714285714286 0.00533333333333333
TF TF:M11587 Factor: foxj3; motif: RCGTMAACAN 0.023566388407479 913 132 15 0.113636363636364 0.0164293537787514
TF TF:M01321 Factor: HOXC-8; motif: NNNNNGTAATTANNNT 0.023566388407479 5641 30 17 0.566666666666667 0.00301365006204574
TF TF:M10589_1 Factor: BSX; motif: NTCRTTAN; match class: 1 0.023566388407479 708 119 12 0.100840336134454 0.0169491525423729
TF TF:M10560_1 Factor: Msx-2; motif: NTCRTTAN; match class: 1 0.023566388407479 708 119 12 0.100840336134454 0.0169491525423729
TF TF:M08874 Factor: E2F1; motif: NNNNNGCGSSAAAN 0.0236289658736399 7201 135 67 0.496296296296296 0.00930426329676434
TF TF:M11118 Factor: OLIG2; motif: AACAKMTGKT 0.02462112614538 208 76 5 0.0657894736842105 0.0240384615384615
TF TF:M11118_1 Factor: OLIG2; motif: AACAKMTGKT; match class: 1 0.02462112614538 208 76 5 0.0657894736842105 0.0240384615384615
TF TF:M04557 Factor: SRY; motif: TCAATAMCATTGA 0.0247903390852688 10084 130 84 0.646153846153846 0.00833002776675922
TF TF:M11307_1 Factor: ATF-2; motif: NNTGACGTMANN; match class: 1 0.0247903390852688 1946 71 16 0.225352112676056 0.00822199383350463
TF TF:M09592_1 Factor: ATF-1; motif: NRTGACGTMAN; match class: 1 0.024810483222965 1255 88 14 0.159090909090909 0.0111553784860558
TF TF:M11447 Factor: Elf-1; motif: NAMCCGGAAGTN 0.0251379766607768 7703 134 70 0.522388059701492 0.00908736855770479
TF TF:M11877 Factor: pax-2; motif: NCGTCACGCNYSRNYGCNYN 0.0252181703478227 11523 107 78 0.728971962616822 0.00676907055454309
TF TF:M04012 Factor: HSFY1; motif: TTTCGAACG 0.0254666855787378 1013 133 16 0.120300751879699 0.0157946692991115
TF TF:M01856 Factor: AML3; motif: AACCACAN 0.025553147780736 1198 9 4 0.444444444444444 0.00333889816360601
TF TF:M04333 Factor: HMX1; motif: ANCAATTAANN 0.025553147780736 1768 57 13 0.228070175438596 0.00735294117647059
TF TF:M10692_1 Factor: HOXB6; motif: GTCGTTAN; match class: 1 0.025553147780736 1009 43 8 0.186046511627907 0.00792864222001982
TF TF:M08920 Factor: JUNB:FOSB; motif: NRTGASTCAT 0.025553147780736 3151 19 9 0.473684210526316 0.00285623611551888
TF TF:M04327 Factor: GSX1; motif: NNYMATTANN 0.0259474968000195 5709 30 17 0.566666666666667 0.00297775442284113
TF TF:M11257_1 Factor: AIBZIP; motif: NRTGACGTCAYN; match class: 1 0.0259474968000195 899 71 10 0.140845070422535 0.0111234705228031
TF TF:M03544_1 Factor: CREB1; motif: NNNNACGTCANN; match class: 1 0.026162400921266 1196 73 12 0.164383561643836 0.0100334448160535
TF TF:M03858 Factor: TCF-3; motif: CTTTGA 0.0262017863896987 12044 35 30 0.857142857142857 0.00249086682165394
TF TF:M10584 Factor: Barhl2; motif: NTAAACGN 0.0262017863896987 1886 109 21 0.192660550458716 0.0111346765641569
TF TF:M10769 Factor: HOXB9; motif: GTCGTAAAAN 0.0262017863896987 207 116 6 0.0517241379310345 0.0289855072463768
TF TF:M10775 Factor: hoxd9; motif: GTCGTAAANN 0.0262017863896987 207 116 6 0.0517241379310345 0.0289855072463768
TF TF:M10777 Factor: hoxd9; motif: GTCGTAAAAN 0.0262017863896987 207 116 6 0.0517241379310345 0.0289855072463768
TF TF:M11303 Factor: batf3; motif: GRTGACGTCATC 0.0262017863896987 614 86 9 0.104651162790698 0.0146579804560261
TF TF:M00805 Factor: TCF-7; motif: TCAAAG 0.0262017863896987 12044 35 30 0.857142857142857 0.00249086682165394
TF TF:M10635 Factor: Nkx2-3; motif: GNCGTTRAG 0.0262017863896987 4594 124 44 0.354838709677419 0.00957771005659556
TF TF:M11976_1 Factor: RFX7; motif: CGTTGCYAY; match class: 1 0.0263519455140881 315 31 4 0.129032258064516 0.0126984126984127
TF TF:M01861 Factor: ATF-1; motif: TNACGTCAN 0.0265164951358452 6294 73 36 0.493150684931507 0.00571973307912297
TF TF:M01752 Factor: ERG; motif: ACCGGAART 0.0266328779923897 9474 134 82 0.611940298507463 0.008655267046654
TF TF:M11404 Factor: Fli-1; motif: NACCGGAARTN 0.0270449268489341 8743 134 77 0.574626865671642 0.00880704563650921
TF TF:M00731 Factor: Osf2; motif: ACCACANM 0.0271008717907118 1303 27 7 0.259259259259259 0.00537221795855718
TF TF:M04710_1 Factor: CHD2; motif: TCTCGCGAG; match class: 1 0.0271855284352966 11477 137 97 0.708029197080292 0.00845168598065697
TF TF:M08917 Factor: GABP-ALPHA; motif: RCCGGAARTNN 0.0271855284352966 2702 137 32 0.233576642335766 0.0118430792005922
TF TF:M09887_1 Factor: CREB1; motif: NRRTGACGTMA; match class: 1 0.0271855284352966 1616 102 18 0.176470588235294 0.0111386138613861
TF TF:M00179 Factor: ATF2; motif: VGTGACGTMACN 0.027314166719323 6065 73 35 0.479452054794521 0.00577081615828524
TF TF:M11124_1 Factor: Olig3; motif: ANCAKMTGTT; match class: 1 0.0276907907912426 218 76 5 0.0657894736842105 0.0229357798165138
TF TF:M11150_1 Factor: msc; motif: NRACAGCTGTYN; match class: 1 0.0278944130040282 331 101 7 0.0693069306930693 0.0211480362537764
TF TF:M00736 Factor: E2F-1:DP-1; motif: TTTCSCGC 0.0278944130040282 10390 129 85 0.65891472868217 0.00818094321462945
TF TF:M04106 Factor: RUNX2; motif: NRACCGCAAACCGCAN 0.0278944130040282 13833 136 111 0.816176470588235 0.00802428974192149
TF TF:M08875 Factor: E2F; motif: NNTTTCGCGCN 0.0278944130040282 6203 129 57 0.441860465116279 0.00918910204739642
TF TF:M11400 Factor: Fli-1; motif: NACCGGAARTN 0.028078160315404 9946 134 85 0.634328358208955 0.00854614920571084
TF TF:M07248_1 Factor: CREB1; motif: NNNNTGACGTNANNN; match class: 1 0.028078160315404 1216 73 12 0.164383561643836 0.00986842105263158
TF TF:M01362 Factor: CART1; motif: NGNNYTAATTARTNNNN 0.0287667760271883 4558 17 10 0.588235294117647 0.00219394471259324
TF TF:M07312_1 Factor: ATF-2; motif: NNTGACGTCAN; match class: 1 0.0287908054839118 1070 72 11 0.152777777777778 0.0102803738317757
TF TF:M11533_1 Factor: E2F-1; motif: NTTTTGGCGCCAWWWN; match class: 1 0.0290458907059248 8705 127 73 0.574803149606299 0.00838598506605399
TF TF:M11419 Factor: ER81; motif: NNCCGGAWGYN 0.0293570444072509 5699 134 55 0.41044776119403 0.00965081593261976
TF TF:M04279 Factor: ALX3; motif: NNYAATTANN 0.0293570444072509 3934 35 15 0.428571428571429 0.0038129130655821
TF TF:M11223 Factor: CREB1; motif: NRTGACGTCANN 0.0294675695678513 2810 86 23 0.267441860465116 0.00818505338078292
TF TF:M07610 Factor: Nrf2; motif: NTGCTGAGTCANN 0.0294675695678513 1012 11 4 0.363636363636364 0.00395256916996047
TF TF:M02265 Factor: NFATc2; motif: TTTTCCA 0.0299879064072143 7752 74 42 0.567567567567568 0.00541795665634675
TF TF:M03560 Factor: PMX1; motif: TAATHA 0.0299931533995918 13914 67 58 0.865671641791045 0.00416846341814
TF TF:M06569 Factor: ZNF775; motif: NYGGGAAAATW 0.0303839222483104 38 125 3 0.024 0.0789473684210526
TF TF:M08525_1 Factor: E2F-1:HES-7; motif: GGCRCGTGSYNNWNGGCGCSM; match class: 1 0.0303839222483104 15268 137 120 0.875912408759124 0.00785957558291852
TF TF:M00017_1 Factor: ATF; motif: CNSTGACGTNNNYC; match class: 1 0.0303839222483104 2222 95 21 0.221052631578947 0.00945094509450945
TF TF:M11603 Factor: TCF-1; motif: ACATCGRGRCGCTGW 0.0304845383632197 16361 137 126 0.91970802919708 0.00770124075545505
TF TF:M07034 Factor: ATF-1; motif: NNNTGACGTNNN 0.0305458093211551 4248 73 27 0.36986301369863 0.00635593220338983
TF TF:M00423 Factor: FOXJ2; motif: AYMATAATATTTKN 0.0305458093211551 6970 93 47 0.505376344086022 0.00674318507890961
TF TF:M11008 Factor: LHX4; motif: NTCRTTAN 0.0305458093211551 6586 133 61 0.458646616541353 0.00926207105982387
TF TF:M03849 Factor: Sox-4; motif: AACAAA 0.0305458093211551 14321 116 98 0.844827586206897 0.00684309754905384
TF TF:M00631_1 Factor: FXR:RXR-alpha; motif: CAAGGTSAWTAACC; match class: 1 0.0305458093211551 484 53 6 0.113207547169811 0.012396694214876
TF TF:M00148 Factor: SRY; motif: AAACWAM 0.0305458093211551 9455 61 41 0.672131147540984 0.00433632998413538
TF TF:M03891 Factor: TTF-1; motif: CTTGASN 0.0305458093211551 3648 64 22 0.34375 0.00603070175438596
TF TF:M01082_1 Factor: BRCA1:USF2; motif: KTNNGTTG; match class: 1 0.0305965942224731 1813 131 23 0.175572519083969 0.0126861555432984
TF TF:M11724 Factor: B-Myb; motif: NTRACSGTYNN 0.0308045116425104 1158 10 4 0.4 0.00345423143350604
TF TF:M11724_1 Factor: B-Myb; motif: NTRACSGTYNN; match class: 1 0.0308045116425104 1158 10 4 0.4 0.00345423143350604
TF TF:M10018_1 Factor: NRF-1; motif: CNSTGCGCATGCGCNNS; match class: 1 0.0310371797260074 851 119 13 0.109243697478992 0.0152761457109283
TF TF:M11313_1 Factor: CREBPA; motif: NRTGACGTMANN; match class: 1 0.0315944719128189 2025 71 16 0.225352112676056 0.00790123456790123
TF TF:M02044 Factor: YY1; motif: GCCGCCATTTTG 0.0318012769412591 6102 132 57 0.431818181818182 0.00934119960668633
TF TF:M08207_1 Factor: E2F-3:TBR2; motif: ANGTGYKANGGCGCSTTNNCRNNT; match class: 1 0.0318012769412591 15466 137 121 0.883211678832117 0.00782361308677098
TF TF:M05870 Factor: ZNF625; motif: NARWTGKATMGA 0.0318012769412591 198 129 6 0.0465116279069767 0.0303030303030303
TF TF:M04393 Factor: LMX1B; motif: NYAATTAN 0.0318491291201855 2301 17 7 0.411764705882353 0.00304215558452847
TF TF:M04059_1 Factor: NRF-1; motif: YGCGCATGCGCN; match class: 1 0.0319355640792274 1033 111 14 0.126126126126126 0.0135527589545015
TF TF:M07250_1 Factor: E2F-1; motif: NNNSSCGCSAANN; match class: 1 0.0321597922299655 5515 133 53 0.398496240601504 0.00961015412511333
TF TF:M11395_1 Factor: Erg; motif: NACCGGAWWTCCGGTN; match class: 1 0.0326554030671129 7963 33 22 0.666666666666667 0.0027627778475449
TF TF:M02109 Factor: NKX2B; motif: CACTTNA 0.0330660458506002 10167 40 30 0.75 0.00295072292711714
TF TF:M09922 Factor: Fra-1; motif: NNNTGAGTCAYN 0.0330660458506002 4573 20 11 0.55 0.00240542313579707
TF TF:M12152 Factor: Sp1; motif: NWRGCCACGCCCMCN 0.0330660458506002 7341 128 64 0.5 0.00871815828906144
TF TF:M05317 Factor: sox-30; motif: YAAATTTTCN 0.0330660458506002 83 60 3 0.05 0.036144578313253
TF TF:M04148 Factor: TFAP2A; motif: NGCCCYNNGGGCN 0.0331025149825249 10040 13 12 0.923076923076923 0.00119521912350598
TF TF:M03811 Factor: AP-2gamma; motif: GCCYNCRGSN 0.0331025149825249 8852 14 12 0.857142857142857 0.00135562584726615
TF TF:M04328_1 Factor: GSX2; motif: NNYMATTANN; match class: 1 0.0331334956104909 3836 17 9 0.529411764705882 0.00234619395203337
TF TF:M11392 Factor: Erg; motif: NACCGGAARYN 0.0332124179956386 8690 134 76 0.567164179104478 0.00874568469505178
TF TF:M07034_1 Factor: ATF-1; motif: NNNTGACGTNNN; match class: 1 0.0333058682778734 1179 88 13 0.147727272727273 0.0110262934690416
TF TF:M11733 Factor: PXR; motif: NYGAACTSNNTGAACTC 0.0333058682778734 2983 21 9 0.428571428571429 0.00301709688233322
TF TF:M11301_1 Factor: B-ATF; motif: NNAYGACACN; match class: 1 0.0333058682778734 1972 115 22 0.191304347826087 0.0111561866125761
TF TF:M01654 Factor: DRI1; motif: AATTAA 0.0335297607493996 10848 135 91 0.674074074074074 0.00838864306784661
TF TF:M03925 Factor: YY2; motif: NCCGCCATNTY 0.0335297607493996 4641 108 39 0.361111111111111 0.00840336134453781
TF TF:M03546 Factor: Dlx-5; motif: AATTAN 0.0335297607493996 10848 135 91 0.674074074074074 0.00838864306784661
TF TF:M09868_1 Factor: ATF-3; motif: GGTSACGTGAN; match class: 1 0.0337692205409915 2116 88 19 0.215909090909091 0.00897920604914934
TF TF:M00039 Factor: CREB; motif: TGACGTMA 0.0337692205409915 5222 73 31 0.424657534246575 0.00593642282650326
TF TF:M11637 Factor: Sox-12; motif: ACCGAACAATN 0.0338500256463048 217 50 4 0.08 0.0184331797235023
TF TF:M00039_1 Factor: CREB; motif: TGACGTMA; match class: 1 0.0338500256463048 1482 88 15 0.170454545454545 0.0101214574898785
TF TF:M02044_1 Factor: YY1; motif: GCCGCCATTTTG; match class: 1 0.0338927682531126 1198 108 15 0.138888888888889 0.0125208681135225
TF TF:M11498 Factor: OC-2; motif: NNATCGATYN 0.0340224470759014 1129 71 11 0.154929577464789 0.00974313551815766
TF TF:M07321 Factor: HNF-4A; motif: NGNNCAAAGKYCAN 0.0341641673409348 1602 18 6 0.333333333333333 0.00374531835205993
TF TF:M00279 Factor: MIF-1; motif: NNGTTGCWWGGYAACNGS 0.034176278174295 11259 101 72 0.712871287128713 0.00639488409272582
TF TF:M10692 Factor: HOXB6; motif: GTCGTTAN 0.0342619443420729 5380 57 26 0.456140350877193 0.00483271375464684
TF TF:M10695 Factor: HOXA6; motif: RTCRTTAN 0.0343167768349824 6486 58 30 0.517241379310345 0.00462534690101758
TF TF:M11124 Factor: Olig3; motif: ANCAKMTGTT 0.0343167768349824 1103 129 16 0.124031007751938 0.014505893019039
TF TF:M00431_1 Factor: E2F-1; motif: TTTSGCGS; match class: 1 0.034707107762711 2271 133 27 0.203007518796992 0.011889035667107
TF TF:M07234_1 Factor: YY1; motif: CAARATGGCNGC; match class: 1 0.0347932817892853 1177 89 13 0.146067415730337 0.0110450297366185
TF TF:M09879_1 Factor: Cdx-2; motif: TTTNATTGCNNT; match class: 1 0.0347932817892853 387 14 3 0.214285714285714 0.00775193798449612
TF TF:M01082 Factor: BRCA1:USF2; motif: KTNNGTTG 0.035101382910282 7155 108 54 0.5 0.00754716981132075
TF TF:M00338_1 Factor: ATF; motif: NTGACGTCANYS; match class: 1 0.0354094445955432 1122 72 11 0.152777777777778 0.00980392156862745
TF TF:M03544 Factor: CREB1; motif: NNNNACGTCANN 0.0358063141590089 4101 73 26 0.356164383561644 0.00633991709339186
TF TF:M10638 Factor: Nkx2-3; motif: NNCGTTRWS 0.0364109322155462 10804 126 85 0.674603174603175 0.00786745649759348
TF TF:M04312 Factor: EMX1; motif: NNTAATTANN 0.0364109322155462 2772 64 18 0.28125 0.00649350649350649
TF TF:M11528_1 Factor: E2F-2; motif: NTTTTGGCGCCAWWWN; match class: 1 0.0365668063652662 4778 126 45 0.357142857142857 0.00941816659690247
TF TF:M10836 Factor: HOXA13; motif: NCCAATAAAAN 0.0368841592849874 624 75 8 0.106666666666667 0.0128205128205128
TF TF:M02074 Factor: GABPalpha; motif: RCCGGAWRYN 0.0372113899822524 4607 134 46 0.343283582089552 0.00998480573041025
TF TF:M09832 Factor: RFX1; motif: NGTTGCCATGG 0.0372113899822524 2370 6 4 0.666666666666667 0.00168776371308017
TF TF:M00738_1 Factor: E2F-4:DP-1; motif: TTTSGCGC; match class: 1 0.0372113899822524 3999 129 40 0.310077519379845 0.0100025006251563
TF TF:M00652_1 Factor: NRF-1; motif: CGCATGCGCR; match class: 1 0.0372417039534657 317 59 5 0.0847457627118644 0.0157728706624606
TF TF:M11307 Factor: ATF-2; motif: NNTGACGTMANN 0.0376635840946746 2085 71 16 0.225352112676056 0.00767386091127098
TF TF:M00739_1 Factor: E2F-4:DP-2; motif: TTTCSCGC; match class: 1 0.0381065100108186 1187 133 17 0.12781954887218 0.0143218197135636
TF TF:M07215 Factor: HNF4A; motif: NTGRACTTTGNNCYN 0.0384002162702084 1479 14 5 0.357142857142857 0.00338066260987153
TF TF:M05650 Factor: ZNF44; motif: NWTTTCTAACCC 0.0384168609851709 55 99 3 0.0303030303030303 0.0545454545454545
TF TF:M11226_1 Factor: ATF-6; motif: GRTGACGTCAYC; match class: 1 0.03941066301999 825 71 9 0.126760563380282 0.0109090909090909
TF TF:M07395 Factor: Sp1; motif: NGGGGCGGGGN 0.0394834063196838 10640 128 85 0.6640625 0.00798872180451128
TF TF:M09896 Factor: E2F-7; motif: GRGGCGGGAANNN 0.0394834063196838 9927 136 85 0.625 0.00856250629596051
TF TF:M04017 Factor: IRF5; motif: NACCGAAACYA 0.0394834063196838 195 97 5 0.0515463917525773 0.0256410256410256
TF TF:M04320 Factor: EVX1; motif: NNTNATTANN 0.0394834063196838 3270 35 13 0.371428571428571 0.00397553516819572
TF TF:M11427 Factor: PEA3; motif: NACCGGAAGTN 0.0396661553351305 10585 137 90 0.656934306569343 0.00850259801606046
TF TF:M11488_1 Factor: CP2; motif: WACCGGTTNNAACCGGWT; match class: 1 0.0397078144986444 635 19 4 0.210526315789474 0.0062992125984252
TF TF:M08925 Factor: JUNB:C-FOS; motif: NATGAGTCATNN 0.0397078144986444 3490 19 9 0.473684210526316 0.00257879656160458
TF TF:M11794 Factor: NR1B1; motif: NRAGGTCANG 0.0401848651109129 2960 8 5 0.625 0.00168918918918919
TF TF:M03977_1 Factor: ETS1; motif: ACCGGAARYN; match class: 1 0.0404430030529088 4677 23 12 0.521739130434783 0.00256574727389352
TF TF:M02052 Factor: EHF; motif: CSCGGAARTN 0.0404430030529088 10107 134 85 0.634328358208955 0.00841001286237261
TF TF:M10072 Factor: sp4; motif: NNGNARGRGGCGGRGCNNRR 0.0404430030529088 10494 128 84 0.65625 0.00800457404230989
TF TF:M11927 Factor: POU3F1; motif: TAATKANNNNNTMATTA 0.0405414241174817 1980 89 18 0.202247191011236 0.00909090909090909
TF TF:M01356 Factor: PMX2B; motif: NNNAATTAATTAANNNG 0.0416472272115056 3215 17 8 0.470588235294118 0.00248833592534992
TF TF:M11090 Factor: TFEA; motif: YRCACGTGACN 0.04215003086844 6189 5 5 1 0.000807884957182097
TF TF:M04279_1 Factor: ALX3; motif: NNYAATTANN; match class: 1 0.0424039814465781 1952 21 7 0.333333333333333 0.00358606557377049
TF TF:M01258 Factor: GABP; motif: CACTTCCGGNNN 0.0424039814465781 2838 94 24 0.25531914893617 0.00845665961945032
TF TF:M07300 Factor: NF-1C; motif: TTGGCNN 0.0424185949826919 6211 39 21 0.538461538461538 0.0033810980518435
TF TF:M03895 Factor: CTCF; motif: WGCGCCMYCTAGYGGYN 0.0424185949826919 9251 49 33 0.673469387755102 0.00356718192627824
TF TF:M11231_1 Factor: CREBL1; motif: GRTGACGTCAYC; match class: 1 0.0427088761155678 841 71 9 0.126760563380282 0.0107015457788347
TF TF:M01385_1 Factor: Pax-4; motif: WNNNYTAATTARYNSNN; match class: 1 0.0427518523803806 2495 17 7 0.411764705882353 0.00280561122244489
TF TF:M11422 Factor: Erm; motif: NRCMGGAAGTN 0.0427518523803806 4669 8 6 0.75 0.00128507174983937
TF TF:M03828 Factor: HNF-4; motif: NNNNNNNGNNCAAAGKYCAN 0.0427518523803806 1160 18 5 0.277777777777778 0.00431034482758621
TF TF:M01862_1 Factor: ATF-2; motif: NNNTGACGTNAN; match class: 1 0.0427518523803806 1007 71 10 0.140845070422535 0.0099304865938431
TF TF:M00917 Factor: CREB; motif: CNNTGACGTMA 0.0432485607855431 5578 73 32 0.438356164383562 0.0057368232341341
TF TF:M11226 Factor: ATF-6; motif: GRTGACGTCAYC 0.0434320142048803 845 71 9 0.126760563380282 0.0106508875739645
TF TF:M07483_1 Factor: CXXC1; motif: KNRNAMCGMWAAMNN; match class: 1 0.0434320142048803 83 70 3 0.0428571428571429 0.036144578313253
TF TF:M09892_1 Factor: E2F-1; motif: NNNNGGCGGGAARN; match class: 1 0.0435145578711612 9162 137 80 0.583941605839416 0.00873171796550971
TF TF:M08933 Factor: JUND:C-FOS; motif: NNATGAGTCATNN 0.0435145578711612 4818 20 11 0.55 0.00228310502283105
TF TF:M06479 Factor: HZF12; motif: NYCTCCGGRTGA 0.0439368808907049 276 103 6 0.058252427184466 0.0217391304347826
TF TF:M10783 Factor: hoxa9; motif: RTCGTWAANN 0.0439368808907049 1897 131 23 0.175572519083969 0.0121244069583553
TF TF:M08587 Factor: GCMb:Dlx-3; motif: ATGCGGGYNNNNNTAATTR 0.0441438652572676 822 60 8 0.133333333333333 0.0097323600973236
TF TF:M07612 Factor: PSF; motif: KWATCCGN 0.0441929828530522 5581 25 14 0.56 0.00250851101953055
TF TF:M04698 Factor: GABP-alpha; motif: CACTTCCGG 0.0441929828530522 3196 137 35 0.255474452554745 0.0109511889862328
TF TF:M08899 Factor: SOX; motif: NNNNCWTTGTT 0.0443166483699732 2066 135 25 0.185185185185185 0.0121006776379477
TF TF:M08313 Factor: GCMa:PEA3; motif: ATRCGGGCGGAAGTR 0.044328290979592 15419 137 120 0.875912408759124 0.00778260587586744
TF TF:M10805 Factor: HOXC10; motif: NGTCGTAAANN 0.044328290979592 419 116 8 0.0689655172413793 0.0190930787589499
TF TF:M02279_1 Factor: CREB1; motif: TGACGTCA; match class: 1 0.0444046529050829 851 71 9 0.126760563380282 0.0105757931844888
TF TF:M03975 Factor: ERG; motif: ACCGGAARTN 0.0445642026744333 10002 134 84 0.626865671641791 0.00839832033593281
TF TF:M11668 Factor: IRF-6; motif: ACCGATACC 0.0447237217017307 406 71 6 0.0845070422535211 0.0147783251231527
TF TF:M08341 Factor: HOXB2:Elk-1; motif: TAATKRCCGGAAGTN 0.0448441979574665 6145 75 35 0.466666666666667 0.00569568755085435
TF TF:M10643 Factor: Homeobox; motif: NCAMTTANC 0.0448441979574665 3983 92 30 0.326086956521739 0.00753201104694954
TF TF:M11535_1 Factor: E2F-4; motif: TTTTGGCGCCAWWN; match class: 1 0.0448441979574665 6532 137 61 0.445255474452555 0.00933864053888549
TF TF:M11033 Factor: Six-2; motif: NCGTATCRYN 0.0448441979574665 8598 127 71 0.559055118110236 0.00825773435682717
TF TF:M00196 Factor: Sp1; motif: NGGGGGCGGGGYN 0.0455453477251321 10233 128 82 0.640625 0.00801329033519007
TF TF:M01759 Factor: AML2; motif: AACCRCAA 0.0455453477251321 3027 30 11 0.366666666666667 0.00363396101750909
TF TF:M11224_1 Factor: CREM; motif: NRTGATGTCAYN; match class: 1 0.0459251342549782 1025 71 10 0.140845070422535 0.00975609756097561
TF TF:M07100 Factor: HSF1; motif: NTTCTRGAANNTTCY 0.0462470445785971 3350 5 4 0.8 0.00119402985074627
TF TF:M03924 Factor: YY1; motif: NNCGCCATTNN 0.0462470445785971 10084 71 48 0.676056338028169 0.00476001586671956
TF TF:M08982 Factor: YY1; motif: NAANATGGCGNNN 0.0464524898746328 7125 66 35 0.53030303030303 0.00491228070175439
TF TF:M00975 Factor: RFX; motif: SHGTTGCSN 0.0464524898746328 5879 7 6 0.857142857142857 0.001020581731587
TF TF:M11309_1 Factor: ATF-2; motif: NRTGACGTMANN; match class: 1 0.0464549418983941 2293 73 17 0.232876712328767 0.00741386829481029
TF TF:M11993 Factor: NFATc4; motif: NAYGGAAANW 0.0465663927712662 944 116 13 0.112068965517241 0.013771186440678
TF TF:M04321_1 Factor: EVX2; motif: NNTNATTANN; match class: 1 0.0465663927712662 1477 35 8 0.228571428571429 0.00541638456330399
TF TF:M00919_1 Factor: E2F; motif: NCSCGCSAAAN; match class: 1 0.0467631481257641 1524 126 19 0.150793650793651 0.0124671916010499
TF TF:M01967 Factor: Pbx; motif: NKTGATTGACRKSN 0.046789663074526 5077 22 12 0.545454545454545 0.0023636005515068
TF TF:M11298_1 Factor: jdp2; motif: NRTGACGTCAYN; match class: 1 0.046789663074526 864 71 9 0.126760563380282 0.0104166666666667
TF TF:M09968_1 Factor: KLF15; motif: RGGGMGGRGNNGGGGGNGG; match class: 1 0.047298596160375 988 7 3 0.428571428571429 0.00303643724696356
TF TF:M07048 Factor: MafG; motif: CMATGACTCAGCAGA 0.047588234301615 6972 8 7 0.875 0.00100401606425703
TF TF:M02053 Factor: ELF1; motif: NCCGGAARTN 0.0476966668296976 6033 134 56 0.417910447761194 0.00928228078899387
TF TF:M02014 Factor: HNF-3beta; motif: NTRTTTRYT 0.0477010719979632 2650 136 30 0.220588235294118 0.0113207547169811
TF TF:M08369 Factor: HOXD12:PEA3; motif: RCCGGAAGTAATAAAM 0.0482051869899738 4596 88 32 0.363636363636364 0.00696257615317668
TF TF:M00920_1 Factor: E2F; motif: NKCGCGCSAAAN; match class: 1 0.0484269576382864 1306 126 17 0.134920634920635 0.0130168453292496
TF TF:M11421 Factor: ER81; motif: NACCGGAAGTN 0.0484269576382864 2341 134 27 0.201492537313433 0.0115335326783426
TF TF:M11303_1 Factor: batf3; motif: GRTGACGTCATC; match class: 1 0.0484269576382864 584 86 8 0.0930232558139535 0.0136986301369863
TF TF:M01321_1 Factor: HOXC-8; motif: NNNNNGTAATTANNNT; match class: 1 0.0484269576382864 4392 22 11 0.5 0.00250455373406193
TF TF:M04064 Factor: Pax-5; motif: NGTCACGCWTSANTGMNY 0.0488161205943676 10122 107 69 0.644859813084112 0.00681683461766449
TF TF:M11413 Factor: ER71; motif: NACCGGAARTN 0.0488161205943676 2111 134 25 0.186567164179104 0.0118427285646613
TF TF:M00041_1 Factor: ATF2:c-Jun; motif: TGACGTYA; match class: 1 0.0488761719197771 1219 71 11 0.154929577464789 0.00902378999179656
TF TF:M06173 Factor: ZNF85; motif: KGGCGGAAGM 0.0488761719197771 100 63 3 0.0476190476190476 0.03
TF TF:M00474 Factor: FOXO1; motif: GNNTTGTTTACNTT 0.0488761719197771 2777 136 31 0.227941176470588 0.0111631256751891
TF TF:M04514 Factor: CPEB1; motif: AATAAAAA 0.0492644162987611 4608 58 23 0.396551724137931 0.00499131944444444
TF TF:M01241_1 Factor: BEN; motif: CWGCGAYA; match class: 1 0.0492644162987611 2097 128 24 0.1875 0.011444921316166
TF TF:M10628_1 Factor: NKX3A; motif: NTCGTTAN; match class: 1 0.0494287832744515 740 29 5 0.172413793103448 0.00675675675675676
TF TF:M02085 Factor: Bcl-6; motif: NTTYCTAGRA 0.0494287832744515 4976 28 14 0.5 0.00281350482315113
TF TF:M08209 Factor: E2F-3:FOXO6; motif: NAATGACACGCGCCCMC 0.0494287832744515 13673 27 25 0.925925925925926 0.00182842097564543
TF TF:M08471 Factor: Fli-1:HOXB13; motif: NNCGGAARYNRTWAA 0.0494505550055701 5224 125 47 0.376 0.00899693721286371
TF TF:M03870 Factor: Fra-2; motif: TGASTCANCN 0.0494853242365991 3634 10 6 0.6 0.00165107319757843
TF TF:M04027 Factor: MEIS1; motif: NTGACAN 0.0495313777538157 3387 24 10 0.416666666666667 0.00295246530853262
TF TF:M01124 Factor: Oct-4; motif: ATTGWSWTGCWAAWN 0.0495313777538157 6034 85 38 0.447058823529412 0.00629764666887637
TF TF:M01035_1 Factor: YY1; motif: NYNKCCATNTT; match class: 1 0.0495313777538157 1112 89 12 0.134831460674157 0.0107913669064748
TF TF:M07284 Factor: Erg; motif: MCAGGAAA 0.0496235245673546 11322 71 52 0.732394366197183 0.00459282812223989
WP WP:WP2361 Gastric Cancer Network 1 6.39014216040007e-08 29 61 7 0.114754098360656 0.241379310344828
WP WP:WP2446 Retinoblastoma Gene in Cancer 6.39014216040007e-08 88 103 12 0.116504854368932 0.136363636363636
WP WP:WP4240 Regulation of sister chromatid separation at the metaphase-anaphase transition 6.39014216040007e-08 16 56 6 0.107142857142857 0.375
WP WP:WP179 Cell Cycle 1.20666566993864e-07 122 119 14 0.117647058823529 0.114754098360656
WP WP:WP2038 Regulation of Microtubule Cytoskeleton 0.0127601012424569 49 63 4 0.0634920634920635 0.0816326530612245
WP WP:WP707 DNA Damage Response 0.0360731965835224 69 34 3 0.0882352941176471 0.0434782608695652
WP WP:WP3878 ATM Signaling Network in Development and Disease 0.0425899404221833 46 56 3 0.0535714285714286 0.0652173913043478

pEpi32 transcription factor target enrichment of top program genes

TF enrichment of pEpi32
Possible regulators of activation of pEpi32 in epithelial cells. (Left) pearson correlation of TF expression and gene expression program activatity in Epithelial cells, (right) negative log p-value for enrichment of TF binding sites among top uniqueness weighted genes for the gene program. Blue bars indicate significant TFs meeting the following criteria: FDR<0.1, overlap > 2, Corr. R > 0, permutation based p-value < 0.05.