pB12 program activity among B cells

Activation of pB12
pB12 gene program activation in B cells.
Gene program activation of pB12 by different cell subtypes
pB12 gene program activation among cells of different subtypes (B cells).

pB12 top program genes

Top genes of pB12 program
Bar plots showing the top genes for each gene program, ranked by (left) unique weights, (right) raw weights.

pB12 gene-set enrichment of top program genes (using g-profiler)

GSEA wth gene profiler of pB12
pB12 gene-set enrichment summary using g-profiler webtool.
Source termID Name Padj Tsize Qsize Overlap Precision Recall
CORUM CORUM:725 P2X7 receptor signalling complex 0.00140795524528087 12 15 3 0.2 0.25
GO:BP GO:0016032 viral process 9.95371787193272e-16 942 18 16 0.888888888888889 0.0169851380042463
GO:BP GO:0044403 biological process involved in symbiotic interaction 1.31697842896308e-15 1001 18 16 0.888888888888889 0.015984015984016
GO:BP GO:0019221 cytokine-mediated signaling pathway 2.80537013638061e-13 810 18 14 0.777777777777778 0.0172839506172839
GO:BP GO:0071345 cellular response to cytokine stimulus 3.16142013169736e-13 1132 38 21 0.552631578947368 0.0185512367491166
GO:BP GO:0034097 response to cytokine 1.00706941249548e-12 1226 18 15 0.833333333333333 0.0122349102773246
GO:BP GO:0010033 response to organic substance 1.54950634331129e-12 3412 43 32 0.744186046511628 0.00937866354044549
GO:BP GO:0071310 cellular response to organic substance 1.54950634331129e-12 2776 39 28 0.717948717948718 0.0100864553314121
GO:BP GO:0006457 protein folding 1.54950634331129e-12 225 44 13 0.295454545454545 0.0577777777777778
GO:BP GO:0002483 antigen processing and presentation of endogenous peptide antigen 3.21624013004057e-12 19 18 6 0.333333333333333 0.315789473684211
GO:BP GO:0019883 antigen processing and presentation of endogenous antigen 2.4464877829209e-11 26 18 6 0.333333333333333 0.230769230769231
GO:BP GO:0006986 response to unfolded protein 2.96766663999518e-11 184 39 11 0.282051282051282 0.0597826086956522
GO:BP GO:0044419 biological process involved in interspecies interaction between organisms 8.26823978504798e-11 2255 18 16 0.888888888888889 0.00709534368070953
GO:BP GO:0035966 response to topologically incorrect protein 8.26823978504798e-11 205 39 11 0.282051282051282 0.0536585365853659
GO:BP GO:0070887 cellular response to chemical stimulus 1.50481696673091e-10 3393 39 28 0.717948717948718 0.00825228411435308
GO:BP GO:0060333 interferon-gamma-mediated signaling pathway 2.8866438583282e-10 88 18 7 0.388888888888889 0.0795454545454545
GO:BP GO:0042026 protein refolding 1.09463591286106e-09 23 15 5 0.333333333333333 0.217391304347826
GO:BP GO:0080134 regulation of response to stress 3.06945706346055e-09 1443 35 18 0.514285714285714 0.0124740124740125
GO:BP GO:1900034 regulation of cellular response to heat 4.33748209926451e-09 79 15 6 0.4 0.0759493670886076
GO:BP GO:0009266 response to temperature stimulus 5.11262936972667e-09 228 39 10 0.256410256410256 0.043859649122807
GO:BP GO:0002480 antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent 5.11262936972667e-09 8 17 4 0.235294117647059 0.5
GO:BP GO:0001916 positive regulation of T cell mediated cytotoxicity 5.11262936972667e-09 26 18 5 0.277777777777778 0.192307692307692
GO:BP GO:0009408 response to heat 5.37378640357129e-09 159 39 9 0.230769230769231 0.0566037735849057
GO:BP GO:0042221 response to chemical 7.98875484010742e-09 4781 43 32 0.744186046511628 0.00669316042668898
GO:BP GO:0002443 leukocyte mediated immunity 8.86851417361955e-09 877 18 11 0.611111111111111 0.0125427594070696
GO:BP GO:0019058 viral life cycle 1.24642743589733e-08 353 15 8 0.533333333333333 0.0226628895184136
GO:BP GO:0002366 leukocyte activation involved in immune response 1.34144346246113e-08 717 39 14 0.358974358974359 0.0195258019525802
GO:BP GO:0034605 cellular response to heat 1.34343268574764e-08 118 39 8 0.205128205128205 0.0677966101694915
GO:BP GO:0002263 cell activation involved in immune response 1.34343268574764e-08 721 39 14 0.358974358974359 0.0194174757281553
GO:BP GO:0001914 regulation of T cell mediated cytotoxicity 1.646398252101e-08 35 18 5 0.277777777777778 0.142857142857143
GO:BP GO:0071346 cellular response to interferon-gamma 1.91680683948908e-08 175 18 7 0.388888888888889 0.04
GO:BP GO:0043312 neutrophil degranulation 2.00939058199288e-08 482 39 12 0.307692307692308 0.024896265560166
GO:BP GO:0031341 regulation of cell killing 2.00939058199288e-08 93 32 7 0.21875 0.0752688172043011
GO:BP GO:0002283 neutrophil activation involved in immune response 2.06647046257548e-08 485 39 12 0.307692307692308 0.0247422680412371
GO:BP GO:0048002 antigen processing and presentation of peptide antigen 2.40469196504489e-08 192 40 9 0.225 0.046875
GO:BP GO:0042119 neutrophil activation 2.49471407741324e-08 498 39 12 0.307692307692308 0.0240963855421687
GO:BP GO:0001912 positive regulation of leukocyte mediated cytotoxicity 2.49471407741324e-08 51 32 6 0.1875 0.117647058823529
GO:BP GO:0002446 neutrophil mediated immunity 2.49471407741324e-08 497 39 12 0.307692307692308 0.0241448692152917
GO:BP GO:0080135 regulation of cellular response to stress 2.54697960274068e-08 725 23 11 0.478260869565217 0.0151724137931034
GO:BP GO:0019885 antigen processing and presentation of endogenous peptide antigen via MHC class I 2.67953293675884e-08 13 17 4 0.235294117647059 0.307692307692308
GO:BP GO:0036230 granulocyte activation 2.67953293675884e-08 504 39 12 0.307692307692308 0.0238095238095238
GO:BP GO:0001913 T cell mediated cytotoxicity 3.03257110366318e-08 42 18 5 0.277777777777778 0.119047619047619
GO:BP GO:0034341 response to interferon-gamma 3.03257110366318e-08 196 18 7 0.388888888888889 0.0357142857142857
GO:BP GO:0002486 antigen processing and presentation of endogenous peptide antigen via MHC class I via ER pathway, TAP-independent 4.43089833669157e-08 3 17 3 0.176470588235294 1
GO:BP GO:0002484 antigen processing and presentation of endogenous peptide antigen via MHC class I via ER pathway 4.43089833669157e-08 3 17 3 0.176470588235294 1
GO:BP GO:0043299 leukocyte degranulation 4.64433715660109e-08 535 39 12 0.307692307692308 0.0224299065420561
GO:BP GO:0031343 positive regulation of cell killing 4.81412656760089e-08 59 32 6 0.1875 0.101694915254237
GO:BP GO:0002711 positive regulation of T cell mediated immunity 5.31670981403309e-08 48 18 5 0.277777777777778 0.104166666666667
GO:BP GO:0002275 myeloid cell activation involved in immune response 5.60203511034597e-08 547 39 12 0.307692307692308 0.0219378427787934
GO:BP GO:0002444 myeloid leukocyte mediated immunity 5.96072683343074e-08 551 39 12 0.307692307692308 0.0217785843920145
GO:BP GO:0019882 antigen processing and presentation 9.4080257929588e-08 234 40 9 0.225 0.0384615384615385
GO:BP GO:0002252 immune effector process 1.17757336609561e-07 1309 33 15 0.454545454545455 0.0114591291061879
GO:BP GO:0002478 antigen processing and presentation of exogenous peptide antigen 1.28753311383216e-07 174 38 8 0.210526315789474 0.0459770114942529
GO:BP GO:0007166 cell surface receptor signaling pathway 1.31817821458802e-07 3210 18 15 0.833333333333333 0.00467289719626168
GO:BP GO:0033554 cellular response to stress 1.3671115895331e-07 2111 40 20 0.5 0.00947418285172904
GO:BP GO:0006950 response to stress 1.3671115895331e-07 4170 40 27 0.675 0.00647482014388489
GO:BP GO:0001910 regulation of leukocyte mediated cytotoxicity 1.59605835019569e-07 74 32 6 0.1875 0.0810810810810811
GO:BP GO:0051641 cellular localization 1.59998628903901e-07 3541 40 25 0.625 0.00706015249929398
GO:BP GO:0061077 chaperone-mediated protein folding 1.63117971579161e-07 61 39 6 0.153846153846154 0.0983606557377049
GO:BP GO:0019884 antigen processing and presentation of exogenous antigen 1.63117971579161e-07 182 38 8 0.210526315789474 0.043956043956044
GO:BP GO:0001775 cell activation 1.86848686214219e-07 1495 49 19 0.387755102040816 0.0127090301003344
GO:BP GO:0070423 nucleotide-binding oligomerization domain containing signaling pathway 2.58045809080769e-07 40 30 5 0.166666666666667 0.125
GO:BP GO:0051085 chaperone cofactor-dependent protein refolding 2.64759453427247e-07 31 39 5 0.128205128205128 0.161290322580645
GO:BP GO:0035872 nucleotide-binding domain, leucine rich repeat containing receptor signaling pathway 2.84228332886886e-07 41 30 5 0.166666666666667 0.121951219512195
GO:BP GO:0045321 leukocyte activation 2.84345715058763e-07 1332 18 11 0.611111111111111 0.00825825825825826
GO:BP GO:0002709 regulation of T cell mediated immunity 3.56075086455837e-07 74 18 5 0.277777777777778 0.0675675675675676
GO:BP GO:0032940 secretion by cell 3.60621247242438e-07 1364 91 25 0.274725274725275 0.0183284457478006
GO:BP GO:0002274 myeloid leukocyte activation 3.7417621473892e-07 667 39 12 0.307692307692308 0.0179910044977511
GO:BP GO:0002708 positive regulation of lymphocyte mediated immunity 4.9302775872286e-07 104 49 7 0.142857142857143 0.0673076923076923
GO:BP GO:0051084 'de novo' posttranslational protein folding 5.08974069797544e-07 36 39 5 0.128205128205128 0.138888888888889
GO:BP GO:0048584 positive regulation of response to stimulus 5.08974069797544e-07 2344 11 10 0.909090909090909 0.00426621160409556
GO:BP GO:0001906 cell killing 5.08974069797544e-07 175 18 6 0.333333333333333 0.0342857142857143
GO:BP GO:0140352 export from cell 7.1861429554718e-07 1418 91 25 0.274725274725275 0.0176304654442877
GO:BP GO:0009628 response to abiotic stimulus 7.99516076766672e-07 1261 39 15 0.384615384615385 0.0118953211736717
GO:BP GO:0006458 'de novo' protein folding 8.47035210498403e-07 40 39 5 0.128205128205128 0.125
GO:BP GO:0001909 leukocyte mediated cytotoxicity 1.11622931453167e-06 107 32 6 0.1875 0.0560747663551402
GO:BP GO:0002824 positive regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains 1.14041026250685e-06 96 18 5 0.277777777777778 0.0520833333333333
GO:BP GO:0002456 T cell mediated immunity 1.2490789791143e-06 98 18 5 0.277777777777778 0.0510204081632653
GO:BP GO:0002474 antigen processing and presentation of peptide antigen via MHC class I 1.29000907194912e-06 99 60 7 0.116666666666667 0.0707070707070707
GO:BP GO:0002705 positive regulation of leukocyte mediated immunity 1.29000907194912e-06 122 49 7 0.142857142857143 0.0573770491803279
GO:BP GO:0002821 positive regulation of adaptive immune response 1.39972518896624e-06 101 18 5 0.277777777777778 0.0495049504950495
GO:BP GO:0048583 regulation of response to stimulus 1.69808299115885e-06 4278 23 18 0.782608695652174 0.00420757363253857
GO:BP GO:0051172 negative regulation of nitrogen compound metabolic process 1.82166162404169e-06 2518 27 16 0.592592592592593 0.00635424940428912
GO:BP GO:0045055 regulated exocytosis 1.83121377442919e-06 785 39 12 0.307692307692308 0.0152866242038217
GO:BP GO:0046903 secretion 1.89063903328865e-06 1501 91 25 0.274725274725275 0.016655562958028
GO:BP GO:0016045 detection of bacterium 1.91996759763253e-06 17 9 3 0.333333333333333 0.176470588235294
GO:BP GO:0051649 establishment of localization in cell 2.05181879230491e-06 2813 40 21 0.525 0.00746533949520085
GO:BP GO:0001817 regulation of cytokine production 2.3059792584991e-06 806 15 8 0.533333333333333 0.00992555831265509
GO:BP GO:0065009 regulation of molecular function 2.3059792584991e-06 3221 45 24 0.533333333333333 0.00745110214219187
GO:BP GO:0031342 negative regulation of cell killing 2.3059792584991e-06 24 7 3 0.428571428571429 0.125
GO:BP GO:0090084 negative regulation of inclusion body assembly 2.38210905660634e-06 11 15 3 0.2 0.272727272727273
GO:BP GO:0010629 negative regulation of gene expression 2.42591471036058e-06 1460 24 12 0.5 0.00821917808219178
GO:BP GO:0098543 detection of other organism 2.52652714294066e-06 19 9 3 0.333333333333333 0.157894736842105
GO:BP GO:0010468 regulation of gene expression 2.57575027489083e-06 5196 16 15 0.9375 0.00288683602771363
GO:BP GO:0097193 intrinsic apoptotic signaling pathway 2.91892463801256e-06 294 50 9 0.18 0.0306122448979592
GO:BP GO:0001816 cytokine production 3.08585698205712e-06 844 15 8 0.533333333333333 0.00947867298578199
GO:BP GO:0002221 pattern recognition receptor signaling pathway 3.42079900803011e-06 213 34 7 0.205882352941176 0.0328638497652582
GO:BP GO:0002753 cytoplasmic pattern recognition receptor signaling pathway 3.56612769044907e-06 73 30 5 0.166666666666667 0.0684931506849315
GO:BP GO:0031396 regulation of protein ubiquitination 3.8890183628182e-06 211 35 7 0.2 0.033175355450237
GO:BP GO:0043618 regulation of transcription from RNA polymerase II promoter in response to stress 4.2578348025158e-06 111 21 5 0.238095238095238 0.045045045045045
GO:BP GO:0002706 regulation of lymphocyte mediated immunity 4.42322597432166e-06 151 49 7 0.142857142857143 0.0463576158940397
GO:BP GO:0031324 negative regulation of cellular metabolic process 4.44408551965335e-06 2719 27 16 0.592592592592593 0.00588451636631114
GO:BP GO:0098581 detection of external biotic stimulus 4.75399333379055e-06 24 9 3 0.333333333333333 0.125
GO:BP GO:0043620 regulation of DNA-templated transcription in response to stress 5.32644775165785e-06 117 21 5 0.238095238095238 0.0427350427350427
GO:BP GO:1903311 regulation of mRNA metabolic process 5.44739826652817e-06 356 23 7 0.304347826086957 0.0196629213483146
GO:BP GO:0044093 positive regulation of molecular function 5.91362030352614e-06 1771 26 13 0.5 0.00734048560135517
GO:BP GO:0060255 regulation of macromolecule metabolic process 6.10819009232697e-06 6603 37 29 0.783783783783784 0.00439194305618658
GO:BP GO:2001233 regulation of apoptotic signaling pathway 6.42183767257766e-06 363 59 10 0.169491525423729 0.0275482093663912
GO:BP GO:0006887 exocytosis 6.5320988209092e-06 904 39 12 0.307692307692308 0.0132743362831858
GO:BP GO:0042590 antigen processing and presentation of exogenous peptide antigen via MHC class I 6.60340333206163e-06 80 60 6 0.1 0.075
GO:BP GO:0010605 negative regulation of macromolecule metabolic process 6.60340333206163e-06 3241 27 17 0.62962962962963 0.00524529466214131
GO:BP GO:0051716 cellular response to stimulus 6.86904553069439e-06 7781 43 35 0.813953488372093 0.00449813648631281
GO:BP GO:0097201 negative regulation of transcription from RNA polymerase II promoter in response to stress 7.44008315078352e-06 12 21 3 0.142857142857143 0.25
GO:BP GO:0030522 intracellular receptor signaling pathway 7.48563892067084e-06 284 43 8 0.186046511627907 0.028169014084507
GO:BP GO:0002822 regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains 7.60909582883732e-06 152 18 5 0.277777777777778 0.0328947368421053
GO:BP GO:0090083 regulation of inclusion body assembly 7.66012969666873e-06 17 15 3 0.2 0.176470588235294
GO:BP GO:0048522 positive regulation of cellular process 8.14350679104913e-06 5757 49 33 0.673469387755102 0.00573215216258468
GO:BP GO:0006402 mRNA catabolic process 8.14350679104913e-06 384 23 7 0.304347826086957 0.0182291666666667
GO:BP GO:1903320 regulation of protein modification by small protein conjugation or removal 8.21489851644e-06 243 22 6 0.272727272727273 0.0246913580246914
GO:BP GO:0097190 apoptotic signaling pathway 9.96326920794091e-06 600 59 12 0.203389830508475 0.02
GO:BP GO:0002682 regulation of immune system process 9.96326920794091e-06 1617 21 11 0.523809523809524 0.00680272108843537
GO:BP GO:0071897 DNA biosynthetic process 1.04282937473672e-05 195 7 4 0.571428571428571 0.0205128205128205
GO:BP GO:0002479 antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent 1.11578683790649e-05 75 38 5 0.131578947368421 0.0666666666666667
GO:BP GO:0002819 regulation of adaptive immune response 1.12563418325904e-05 167 18 5 0.277777777777778 0.029940119760479
GO:BP GO:1902533 positive regulation of intracellular signal transduction 1.15290593922883e-05 1037 15 8 0.533333333333333 0.0077145612343298
GO:BP GO:0002697 regulation of immune effector process 1.28061340913076e-05 461 21 7 0.333333333333333 0.0151843817787419
GO:BP GO:0009595 detection of biotic stimulus 1.35356808919063e-05 36 9 3 0.333333333333333 0.0833333333333333
GO:BP GO:0051131 chaperone-mediated protein complex assembly 1.35397138721929e-05 21 15 3 0.2 0.142857142857143
GO:BP GO:0016192 vesicle-mediated transport 1.39165675367017e-05 2180 73 25 0.342465753424658 0.0114678899082569
GO:BP GO:0006401 RNA catabolic process 1.42902222060524e-05 424 23 7 0.304347826086957 0.0165094339622642
GO:BP GO:0043484 regulation of RNA splicing 1.47667170680828e-05 160 36 6 0.166666666666667 0.0375
GO:BP GO:0002831 regulation of response to biotic stimulus 1.55976158167845e-05 415 9 5 0.555555555555556 0.0120481927710843
GO:BP GO:0034620 cellular response to unfolded protein 1.57029358906984e-05 149 39 6 0.153846153846154 0.0402684563758389
GO:BP GO:0009892 negative regulation of metabolic process 1.5736115201018e-05 3479 27 17 0.62962962962963 0.00488646162690428
GO:BP GO:0031329 regulation of cellular catabolic process 1.81017668970324e-05 866 24 9 0.375 0.0103926096997691
GO:BP GO:0050778 positive regulation of immune response 1.91939773274097e-05 753 10 6 0.6 0.00796812749003984
GO:BP GO:0070841 inclusion body assembly 1.91939773274097e-05 24 15 3 0.2 0.125
GO:BP GO:0044265 cellular macromolecule catabolic process 1.92511583471196e-05 1231 45 14 0.311111111111111 0.0113728675873274
GO:BP GO:0065003 protein-containing complex assembly 2.02591488177715e-05 1680 18 10 0.555555555555556 0.00595238095238095
GO:BP GO:0010467 gene expression 2.13295354930743e-05 6179 16 15 0.9375 0.00242757727787668
GO:BP GO:0048523 negative regulation of cellular process 2.20041835619435e-05 5139 27 20 0.740740740740741 0.00389180774469741
GO:BP GO:0002703 regulation of leukocyte mediated immunity 2.44565423894394e-05 205 49 7 0.142857142857143 0.0341463414634146
GO:BP GO:0030163 protein catabolic process 2.45771491424805e-05 974 49 13 0.26530612244898 0.013347022587269
GO:BP GO:0042592 homeostatic process 2.49236864998326e-05 1981 62 21 0.338709677419355 0.0106007067137809
GO:BP GO:0010558 negative regulation of macromolecule biosynthetic process 2.6685141538121e-05 1639 27 12 0.444444444444444 0.0073215375228798
GO:BP GO:0002376 immune system process 2.67684489458062e-05 3278 60 27 0.45 0.00823672971323978
GO:BP GO:0035967 cellular response to topologically incorrect protein 2.79788011518339e-05 168 39 6 0.153846153846154 0.0357142857142857
GO:BP GO:1903362 regulation of cellular protein catabolic process 2.79788011518339e-05 257 15 5 0.333333333333333 0.0194552529182879
GO:BP GO:0019222 regulation of metabolic process 2.98355716445524e-05 7148 37 29 0.783783783783784 0.0040570789031897
GO:BP GO:0060337 type I interferon signaling pathway 2.9950551466662e-05 95 17 4 0.235294117647059 0.0421052631578947
GO:BP GO:2001242 regulation of intrinsic apoptotic signaling pathway 3.0630225230357e-05 167 40 6 0.15 0.0359281437125748
GO:BP GO:0042981 regulation of apoptotic process 3.0630225230357e-05 1549 49 16 0.326530612244898 0.0103292446739832
GO:BP GO:0071357 cellular response to type I interferon 3.0630225230357e-05 96 17 4 0.235294117647059 0.0416666666666667
GO:BP GO:0002699 positive regulation of immune effector process 3.08079299094807e-05 215 49 7 0.142857142857143 0.0325581395348837
GO:BP GO:0010941 regulation of cell death 3.2271452219466e-05 1720 50 17 0.34 0.00988372093023256
GO:BP GO:0012501 programmed cell death 3.22830166894797e-05 2143 50 19 0.38 0.00886607559496034
GO:BP GO:0006955 immune response 3.4058342502612e-05 2311 18 11 0.611111111111111 0.00475984422327997
GO:BP GO:0034340 response to type I interferon 3.61395959373452e-05 101 17 4 0.235294117647059 0.0396039603960396
GO:BP GO:0010604 positive regulation of macromolecule metabolic process 3.68253177870167e-05 3483 16 12 0.75 0.00344530577088717
GO:BP GO:0031327 negative regulation of cellular biosynthetic process 3.71102257355569e-05 1707 27 12 0.444444444444444 0.0070298769771529
GO:BP GO:0045087 innate immune response 3.74007833001947e-05 998 18 8 0.444444444444444 0.00801603206412826
GO:BP GO:0007165 signal transduction 3.74007833001947e-05 6309 35 26 0.742857142857143 0.00412109684577588
GO:BP GO:0050776 regulation of immune response 3.74007833001947e-05 996 18 8 0.444444444444444 0.00803212851405622
GO:BP GO:0043067 regulation of programmed cell death 3.74007833001947e-05 1582 49 16 0.326530612244898 0.0101137800252845
GO:BP GO:0021953 central nervous system neuron differentiation 3.79854204017333e-05 188 10 4 0.4 0.0212765957446809
GO:BP GO:0070431 nucleotide-binding oligomerization domain containing 2 signaling pathway 3.80144709280691e-05 16 30 3 0.1 0.1875
GO:BP GO:1903706 regulation of hemopoiesis 3.87602411913209e-05 424 18 6 0.333333333333333 0.0141509433962264
GO:BP GO:0006915 apoptotic process 3.98489744456882e-05 1990 59 20 0.338983050847458 0.0100502512562814
GO:BP GO:0051338 regulation of transferase activity 4.0656378187252e-05 1035 23 9 0.391304347826087 0.00869565217391304
GO:BP GO:0009893 positive regulation of metabolic process 4.0656378187252e-05 3783 43 23 0.534883720930233 0.00607983082209886
GO:BP GO:0009890 negative regulation of biosynthetic process 4.25932565405715e-05 1740 27 12 0.444444444444444 0.00689655172413793
GO:BP GO:0009057 macromolecule catabolic process 4.30975467163349e-05 1468 59 17 0.288135593220339 0.0115803814713896
GO:BP GO:0045088 regulation of innate immune response 4.50332418569145e-05 309 7 4 0.571428571428571 0.0129449838187702
GO:BP GO:0001819 positive regulation of cytokine production 4.70315129314316e-05 452 49 9 0.183673469387755 0.0199115044247788
GO:BP GO:0051090 regulation of DNA-binding transcription factor activity 4.95400860925297e-05 456 49 9 0.183673469387755 0.0197368421052632
GO:BP GO:0016567 protein ubiquitination 4.95400860925297e-05 892 15 7 0.466666666666667 0.007847533632287
GO:BP GO:0031647 regulation of protein stability 4.95400860925297e-05 300 15 5 0.333333333333333 0.0166666666666667
GO:BP GO:0017015 regulation of transforming growth factor beta receptor signaling pathway 4.95400860925297e-05 129 15 4 0.266666666666667 0.0310077519379845
GO:BP GO:0060548 negative regulation of cell death 5.06194863418709e-05 1038 50 13 0.26 0.01252408477842
GO:BP GO:0021954 central nervous system neuron development 5.14485795702249e-05 84 7 3 0.428571428571429 0.0357142857142857
GO:BP GO:1902531 regulation of intracellular signal transduction 5.14485795702249e-05 1842 49 17 0.346938775510204 0.00922909880564604
GO:BP GO:1903844 regulation of cellular response to transforming growth factor beta stimulus 5.30335808895475e-05 132 15 4 0.266666666666667 0.0303030303030303
GO:BP GO:0044257 cellular protein catabolic process 5.30847239577172e-05 813 45 11 0.244444444444444 0.013530135301353
GO:BP GO:0043488 regulation of mRNA stability 5.40869581793279e-05 191 23 5 0.217391304347826 0.0261780104712042
GO:BP GO:0034655 nucleobase-containing compound catabolic process 5.4109381389135e-05 567 15 6 0.4 0.0105820105820106
GO:BP GO:0009894 regulation of catabolic process 5.52001431863216e-05 1033 24 9 0.375 0.00871248789932236
GO:BP GO:2000112 regulation of cellular macromolecule biosynthetic process 5.59129919797002e-05 4071 31 19 0.612903225806452 0.0046671579464505
GO:BP GO:0048518 positive regulation of biological process 5.65575912945722e-05 6363 43 30 0.697674418604651 0.00471475719000472
GO:BP GO:0072594 establishment of protein localization to organelle 5.78919008658494e-05 584 40 9 0.225 0.0154109589041096
GO:BP GO:0043161 proteasome-mediated ubiquitin-dependent protein catabolic process 5.81393831137966e-05 434 40 8 0.2 0.0184331797235023
GO:BP GO:0043933 protein-containing complex subunit organization 6.05001881156362e-05 1963 18 10 0.555555555555556 0.00509424350483953
GO:BP GO:0010556 regulation of macromolecule biosynthetic process 6.05001881156362e-05 4102 31 19 0.612903225806452 0.00463188688444661
GO:BP GO:0043066 negative regulation of apoptotic process 6.35360955904406e-05 921 49 12 0.244897959183673 0.0130293159609121
GO:BP GO:0043487 regulation of RNA stability 6.39705327182971e-05 201 23 5 0.217391304347826 0.0248756218905473
GO:BP GO:0016071 mRNA metabolic process 6.39705327182971e-05 874 16 7 0.4375 0.0080091533180778
GO:BP GO:0008219 cell death 6.39705327182971e-05 2292 63 22 0.349206349206349 0.00959860383944154
GO:BP GO:0033674 positive regulation of kinase activity 6.47465720641892e-05 608 9 5 0.555555555555556 0.00822368421052632
GO:BP GO:0051092 positive regulation of NF-kappaB transcription factor activity 6.47476811092895e-05 162 49 6 0.122448979591837 0.037037037037037
GO:BP GO:0034622 cellular protein-containing complex assembly 6.49318763655075e-05 1107 18 8 0.444444444444444 0.00722673893405601
GO:BP GO:0046700 heterocycle catabolic process 6.88085704513262e-05 602 15 6 0.4 0.00996677740863787
GO:BP GO:0044270 cellular nitrogen compound catabolic process 7.25091227124117e-05 608 15 6 0.4 0.00986842105263158
GO:BP GO:0010608 posttranscriptional regulation of gene expression 7.31625198604287e-05 896 16 7 0.4375 0.0078125
GO:BP GO:0032446 protein modification by small protein conjugation 7.38321066255703e-05 973 15 7 0.466666666666667 0.00719424460431655
GO:BP GO:0007178 transmembrane receptor protein serine/threonine kinase signaling pathway 7.42581673477779e-05 369 7 4 0.571428571428571 0.010840108401084
GO:BP GO:0043069 negative regulation of programmed cell death 7.45851597436996e-05 943 49 12 0.244897959183673 0.0127253446447508
GO:BP GO:0051091 positive regulation of DNA-binding transcription factor activity 7.73969712750894e-05 270 66 8 0.121212121212121 0.0296296296296296
GO:BP GO:0061013 regulation of mRNA catabolic process 7.83734595398049e-05 213 23 5 0.217391304347826 0.0234741784037559
GO:BP GO:0019439 aromatic compound catabolic process 7.96537537195964e-05 623 15 6 0.4 0.00963081861958266
GO:BP GO:0048519 negative regulation of biological process 8.06338542300628e-05 5757 16 14 0.875 0.00243182212958138
GO:BP GO:1903507 negative regulation of nucleic acid-templated transcription 8.24218250550219e-05 1339 16 8 0.5 0.00597460791635549
GO:BP GO:1902679 negative regulation of RNA biosynthetic process 8.29777154594747e-05 1341 16 8 0.5 0.00596569724086503
GO:BP GO:0022607 cellular component assembly 8.57311716672966e-05 3010 19 12 0.631578947368421 0.00398671096345515
GO:BP GO:0002684 positive regulation of immune system process 8.6395007799669e-05 1065 10 6 0.6 0.00563380281690141
GO:BP GO:2001243 negative regulation of intrinsic apoptotic signaling pathway 8.81747121488493e-05 100 23 4 0.173913043478261 0.04
GO:BP GO:0045646 regulation of erythrocyte differentiation 8.95886477238386e-05 47 15 3 0.2 0.0638297872340425
GO:BP GO:1901361 organic cyclic compound catabolic process 9.64338233030298e-05 651 15 6 0.4 0.00921658986175115
GO:BP GO:0031326 regulation of cellular biosynthetic process 9.68715027138763e-05 4273 31 19 0.612903225806452 0.00444652468991341
GO:BP GO:0045935 positive regulation of nucleobase-containing compound metabolic process 9.816370110002e-05 1887 16 9 0.5625 0.00476947535771065
GO:BP GO:0051606 detection of stimulus 0.000102379193773741 687 9 5 0.555555555555556 0.00727802037845706
GO:BP GO:0051347 positive regulation of transferase activity 0.000103408690729936 689 9 5 0.555555555555556 0.00725689404934688
GO:BP GO:0031347 regulation of defense response 0.000112520695785989 704 9 5 0.555555555555556 0.00710227272727273
GO:BP GO:0098542 defense response to other organism 0.000112599847353939 1218 18 8 0.444444444444444 0.00656814449917898
GO:BP GO:0009967 positive regulation of signal transduction 0.000113346989173341 1598 11 7 0.636363636363636 0.00438047559449312
GO:BP GO:0010498 proteasomal protein catabolic process 0.000113346989173341 491 40 8 0.2 0.0162932790224033
GO:BP GO:2001234 negative regulation of apoptotic signaling pathway 0.000113439595450665 236 23 5 0.217391304347826 0.0211864406779661
GO:BP GO:2000113 negative regulation of cellular macromolecule biosynthetic process 0.000113439595450665 1628 27 11 0.407407407407407 0.00675675675675676
GO:BP GO:0034613 cellular protein localization 0.000113439595450665 2014 35 14 0.4 0.00695134061569017
GO:BP GO:0043085 positive regulation of catalytic activity 0.000113439595450665 1418 16 8 0.5 0.00564174894217207
GO:BP GO:0070727 cellular macromolecule localization 0.000119227917923121 2024 35 14 0.4 0.00691699604743083
GO:BP GO:0023052 signaling 0.000121707714185939 6810 35 26 0.742857142857143 0.00381791483113069
GO:BP GO:0009889 regulation of biosynthetic process 0.000121707714185939 4361 31 19 0.612903225806452 0.00435679889933501
GO:BP GO:0051972 regulation of telomerase activity 0.000125800701755122 51 16 3 0.1875 0.0588235294117647
GO:BP GO:0051253 negative regulation of RNA metabolic process 0.000126265009519242 1445 16 8 0.5 0.0055363321799308
GO:BP GO:0007154 cell communication 0.000127525121311795 6829 35 26 0.742857142857143 0.00380729242934544
GO:BP GO:0002224 toll-like receptor signaling pathway 0.000127586728363341 161 34 5 0.147058823529412 0.031055900621118
GO:BP GO:0051707 response to other organism 0.000129355545422602 1592 49 15 0.306122448979592 0.00942211055276382
GO:BP GO:0043207 response to external biotic stimulus 0.000129382963569255 1594 49 15 0.306122448979592 0.00941028858218319
GO:BP GO:0008380 RNA splicing 0.000129382963569255 456 44 8 0.181818181818182 0.0175438596491228
GO:BP GO:0019219 regulation of nucleobase-containing compound metabolic process 0.00013161637050069 4091 16 12 0.75 0.00293326814959668
GO:BP GO:0042176 regulation of protein catabolic process 0.000136345606869589 401 15 5 0.333333333333333 0.0124688279301746
GO:BP GO:0061136 regulation of proteasomal protein catabolic process 0.000140778936355162 186 15 4 0.266666666666667 0.021505376344086
GO:BP GO:0007167 enzyme linked receptor protein signaling pathway 0.000141728269318735 1103 4 4 1 0.00362647325475975
GO:BP GO:0006605 protein targeting 0.000146946861948472 441 3 3 1 0.00680272108843537
GO:BP GO:0009607 response to biotic stimulus 0.000157766775831104 1626 49 15 0.306122448979592 0.00922509225092251
GO:BP GO:0050821 protein stabilization 0.000158292293695396 193 15 4 0.266666666666667 0.0207253886010363
GO:BP GO:0044085 cellular component biogenesis 0.000161791148761731 3257 19 12 0.631578947368421 0.00368437212158428
GO:BP GO:0034654 nucleobase-containing compound biosynthetic process 0.000167011130622729 4199 16 12 0.75 0.00285782329125982
GO:BP GO:0050790 regulation of catalytic activity 0.000172480803720242 2545 23 12 0.521739130434783 0.00471512770137525
GO:BP GO:0010628 positive regulation of gene expression 0.000176158652725864 1160 15 7 0.466666666666667 0.00603448275862069
GO:BP GO:0002449 lymphocyte mediated immunity 0.000189146517550978 354 18 5 0.277777777777778 0.0141242937853107
GO:BP GO:0045934 negative regulation of nucleobase-containing compound metabolic process 0.000189146517550978 1548 16 8 0.5 0.00516795865633075
GO:BP GO:0018130 heterocycle biosynthetic process 0.000193213207502738 4269 16 12 0.75 0.0028109627547435
GO:BP GO:0010647 positive regulation of cell communication 0.000193527549672863 1777 11 7 0.636363636363636 0.00393922341024198
GO:BP GO:0007179 transforming growth factor beta receptor signaling pathway 0.000194115919461641 206 15 4 0.266666666666667 0.0194174757281553
GO:BP GO:0019438 aromatic compound biosynthetic process 0.00019451521306705 4278 16 12 0.75 0.00280504908835905
GO:BP GO:0023056 positive regulation of signaling 0.00019451521306705 1782 11 7 0.636363636363636 0.00392817059483726
GO:BP GO:0070647 protein modification by small protein conjugation or removal 0.00019451521306705 1184 15 7 0.466666666666667 0.00591216216216216
GO:BP GO:0035556 intracellular signal transduction 0.000197469997104974 2772 50 20 0.4 0.00721500721500722
GO:BP GO:0031399 regulation of protein modification process 0.000203206410057334 1671 49 15 0.306122448979592 0.00897666068222621
GO:BP GO:0002460 adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains 0.000205605738907056 363 18 5 0.277777777777778 0.0137741046831956
GO:BP GO:0044248 cellular catabolic process 0.000207711603469903 2347 25 12 0.48 0.00511291009799744
GO:BP GO:0000122 negative regulation of transcription by RNA polymerase II 0.000208475784298703 901 49 11 0.224489795918367 0.0122086570477248
GO:BP GO:0048585 negative regulation of response to stimulus 0.000208475784298703 1733 23 10 0.434782608695652 0.00577034045008656
GO:BP GO:0001934 positive regulation of protein phosphorylation 0.000213330404646734 840 9 5 0.555555555555556 0.00595238095238095
GO:BP GO:0045860 positive regulation of protein kinase activity 0.000225974624892284 534 7 4 0.571428571428571 0.00749063670411985
GO:BP GO:1903050 regulation of proteolysis involved in cellular protein catabolic process 0.000243352434258359 221 15 4 0.266666666666667 0.0180995475113122
GO:BP GO:0051603 proteolysis involved in cellular protein catabolic process 0.000266974044136047 750 40 9 0.225 0.012
GO:BP GO:0002250 adaptive immune response 0.000267411548404023 689 25 7 0.28 0.0101596516690856
GO:BP GO:1901362 organic cyclic compound biosynthetic process 0.000273946120626044 4439 16 12 0.75 0.0027033115566569
GO:BP GO:0043170 macromolecule metabolic process 0.000273946120626044 9796 47 39 0.829787234042553 0.00398121682319314
GO:BP GO:0019538 protein metabolic process 0.000307771062123406 5808 54 32 0.592592592592593 0.00550964187327824
GO:BP GO:0043549 regulation of kinase activity 0.000317521235310505 921 9 5 0.555555555555556 0.00542888165038002
GO:BP GO:0042327 positive regulation of phosphorylation 0.000325604791602306 927 9 5 0.555555555555556 0.00539374325782093
GO:BP GO:0046635 positive regulation of alpha-beta T cell activation 0.000334165851958595 67 18 3 0.166666666666667 0.0447761194029851
GO:BP GO:0051171 regulation of nitrogen compound metabolic process 0.000334165851958595 5848 43 27 0.627906976744186 0.00461696306429549
GO:BP GO:0051246 regulation of protein metabolic process 0.00034092549060303 2704 49 19 0.387755102040816 0.00702662721893491
GO:BP GO:1901565 organonitrogen compound catabolic process 0.000391091080136425 1358 49 13 0.26530612244898 0.00957290132547865
GO:BP GO:0071560 cellular response to transforming growth factor beta stimulus 0.000399977765740891 256 15 4 0.266666666666667 0.015625
GO:BP GO:0010833 telomere maintenance via telomere lengthening 0.000404346127856413 82 16 3 0.1875 0.0365853658536585
GO:BP GO:0090092 regulation of transmembrane receptor protein serine/threonine kinase signaling pathway 0.000404346127856413 257 15 4 0.266666666666667 0.0155642023346304
GO:BP GO:0030512 negative regulation of transforming growth factor beta receptor signaling pathway 0.000405999141463589 88 15 3 0.2 0.0340909090909091
GO:BP GO:0070498 interleukin-1-mediated signaling pathway 0.000407068388738102 105 35 4 0.114285714285714 0.0380952380952381
GO:BP GO:0042269 regulation of natural killer cell mediated cytotoxicity 0.000424722879831688 41 32 3 0.09375 0.0731707317073171
GO:BP GO:0071559 response to transforming growth factor beta 0.000427525728841576 262 15 4 0.266666666666667 0.0152671755725191
GO:BP GO:0050777 negative regulation of immune response 0.000427536491294369 157 9 3 0.333333333333333 0.0191082802547771
GO:BP GO:0045637 regulation of myeloid cell differentiation 0.000430142959910359 263 15 4 0.266666666666667 0.0152091254752852
GO:BP GO:0006396 RNA processing 0.000434775780964749 964 59 12 0.203389830508475 0.012448132780083
GO:BP GO:0045937 positive regulation of phosphate metabolic process 0.000435084331054303 1001 9 5 0.555555555555556 0.004995004995005
GO:BP GO:0010562 positive regulation of phosphorus metabolic process 0.000435084331054303 1001 9 5 0.555555555555556 0.004995004995005
GO:BP GO:0002757 immune response-activating signal transduction 0.000435676597005523 477 9 4 0.444444444444444 0.00838574423480084
GO:BP GO:0033365 protein localization to organelle 0.000435676597005523 1017 40 10 0.25 0.00983284169124877
GO:BP GO:0002429 immune response-activating cell surface receptor signaling pathway 0.000435676597005523 477 9 4 0.444444444444444 0.00838574423480084
GO:BP GO:0050794 regulation of cellular process 0.00043591347772198 11473 38 35 0.921052631578947 0.00305064063453325
GO:BP GO:0010561 negative regulation of glycoprotein biosynthetic process 0.000441068189299402 25 54 3 0.0555555555555556 0.12
GO:BP GO:0050896 response to stimulus 0.000447966870700354 9407 40 33 0.825 0.00350802593813118
GO:BP GO:0051173 positive regulation of nitrogen compound metabolic process 0.000472393491881709 3083 16 10 0.625 0.00324359390204346
GO:BP GO:0002440 production of molecular mediator of immune response 0.000475567984522788 189 21 4 0.19047619047619 0.0211640211640212
GO:BP GO:0032268 regulation of cellular protein metabolic process 0.00048933783947075 2541 49 18 0.36734693877551 0.00708382526564345
GO:BP GO:2001235 positive regulation of apoptotic signaling pathway 0.000491025264517204 129 59 5 0.0847457627118644 0.0387596899224806
GO:BP GO:0045892 negative regulation of transcription, DNA-templated 0.000491025264517204 1337 26 9 0.346153846153846 0.00673148840688108
GO:BP GO:0006446 regulation of translational initiation 0.000503933951037026 80 49 4 0.0816326530612245 0.05
GO:BP GO:0006508 proteolysis 0.000504823896074777 1836 49 15 0.306122448979592 0.00816993464052288
GO:BP GO:0032101 regulation of response to external stimulus 0.000521378718970562 1051 9 5 0.555555555555556 0.00475737392959087
GO:BP GO:0002715 regulation of natural killer cell mediated immunity 0.000521378718970562 45 32 3 0.09375 0.0666666666666667
GO:BP GO:0002768 immune response-regulating cell surface receptor signaling pathway 0.000544794574432976 512 9 4 0.444444444444444 0.0078125
GO:BP GO:0002764 immune response-regulating signaling pathway 0.000552855087177548 515 9 4 0.444444444444444 0.00776699029126214
GO:BP GO:0031401 positive regulation of protein modification process 0.000567975301739264 1074 9 5 0.555555555555556 0.00465549348230913
GO:BP GO:0080090 regulation of primary metabolic process 0.000568553020877888 6053 43 27 0.627906976744186 0.00446059805055344
GO:BP GO:0006511 ubiquitin-dependent protein catabolic process 0.000580721236308632 655 40 8 0.2 0.0122137404580153
GO:BP GO:0045639 positive regulation of myeloid cell differentiation 0.000580721236308632 103 15 3 0.2 0.029126213592233
GO:BP GO:1903019 negative regulation of glycoprotein metabolic process 0.000583093159107154 28 54 3 0.0555555555555556 0.107142857142857
GO:BP GO:0007249 I-kappaB kinase/NF-kappaB signaling 0.000586127656387719 291 87 8 0.0919540229885057 0.0274914089347079
GO:BP GO:0019941 modification-dependent protein catabolic process 0.000618150036952758 662 40 8 0.2 0.0120845921450151
GO:BP GO:0071363 cellular response to growth factor stimulus 0.000619120097513436 731 7 4 0.571428571428571 0.00547195622435021
GO:BP GO:0032270 positive regulation of cellular protein metabolic process 0.000622242293030802 1477 15 7 0.466666666666667 0.004739336492891
GO:BP GO:0008104 protein localization 0.000633028766247342 2770 35 15 0.428571428571429 0.00541516245487365
GO:BP GO:0045859 regulation of protein kinase activity 0.000649659794674524 809 3 3 1 0.00370828182941904
GO:BP GO:0043632 modification-dependent macromolecule catabolic process 0.000680955489383027 673 40 8 0.2 0.011887072808321
GO:BP GO:0070848 response to growth factor 0.000704170144348537 759 7 4 0.571428571428571 0.00527009222661397
GO:BP GO:0045595 regulation of cell differentiation 0.000727359245613858 1679 18 8 0.444444444444444 0.00476474091721263
GO:BP GO:0031325 positive regulation of cellular metabolic process 0.000731919458852692 3274 16 10 0.625 0.0030543677458766
GO:BP GO:0034645 cellular macromolecule biosynthetic process 0.000741090479777088 5051 31 19 0.612903225806452 0.00376163136012671
GO:BP GO:0090287 regulation of cellular response to growth factor stimulus 0.000758490573618624 315 15 4 0.266666666666667 0.0126984126984127
GO:BP GO:0009056 catabolic process 0.000763146131300162 2744 25 12 0.48 0.0043731778425656
GO:BP GO:0046718 viral entry into host cell 0.000763146131300162 141 32 4 0.125 0.0283687943262411
GO:BP GO:0002253 activation of immune response 0.000763146131300162 568 9 4 0.444444444444444 0.00704225352112676
GO:BP GO:0030218 erythrocyte differentiation 0.000777546465031928 116 15 3 0.2 0.0258620689655172
GO:BP GO:0044271 cellular nitrogen compound biosynthetic process 0.000798786262773147 5017 16 12 0.75 0.00239186764999003
GO:BP GO:2001240 negative regulation of extrinsic apoptotic signaling pathway in absence of ligand 0.00080318251034732 35 49 3 0.0612244897959184 0.0857142857142857
GO:BP GO:1901099 negative regulation of signal transduction in absence of ligand 0.00080318251034732 35 49 3 0.0612244897959184 0.0857142857142857
GO:BP GO:2000278 regulation of DNA biosynthetic process 0.000843693663366071 112 16 3 0.1875 0.0267857142857143
GO:BP GO:0051247 positive regulation of protein metabolic process 0.000844300109606562 1564 15 7 0.466666666666667 0.00447570332480818
GO:BP GO:0009059 macromolecule biosynthetic process 0.000850702765333969 5114 31 19 0.612903225806452 0.00371529135705905
GO:BP GO:0045184 establishment of protein localization 0.00088774548921893 2035 85 22 0.258823529411765 0.0108108108108108
GO:BP GO:0046634 regulation of alpha-beta T cell activation 0.000905827892785231 102 18 3 0.166666666666667 0.0294117647058824
GO:BP GO:0031397 negative regulation of protein ubiquitination 0.000909149947413494 83 22 3 0.136363636363636 0.036144578313253
GO:BP GO:0034101 erythrocyte homeostasis 0.000909149947413494 124 15 3 0.2 0.0241935483870968
GO:BP GO:0048024 regulation of mRNA splicing, via spliceosome 0.000980999840088695 119 16 3 0.1875 0.0252100840336134
GO:BP GO:0031323 regulation of cellular metabolic process 0.000996833147193492 6269 43 27 0.627906976744186 0.00430690700271176
GO:BP GO:0006952 defense response 0.000997381232831614 1818 10 6 0.6 0.0033003300330033
GO:BP GO:0001932 regulation of protein phosphorylation 0.000997381232831614 1240 9 5 0.555555555555556 0.00403225806451613
GO:BP GO:0044409 entry into host 0.00100267710433819 154 32 4 0.125 0.025974025974026
GO:BP GO:0006259 DNA metabolic process 0.00100485948049605 965 3 3 1 0.00310880829015544
GO:BP GO:0065008 regulation of biological quality 0.00100963269825093 4131 40 20 0.5 0.00484144274993948
GO:BP GO:0061024 membrane organization 0.00102527145247441 973 3 3 1 0.00308324768756423
GO:BP GO:0044238 primary metabolic process 0.00104125807218664 10584 59 48 0.813559322033898 0.00453514739229025
GO:BP GO:2001236 regulation of extrinsic apoptotic signaling pathway 0.00109822252801192 159 59 5 0.0847457627118644 0.0314465408805031
GO:BP GO:1901575 organic substance catabolic process 0.0011046844357249 2267 15 8 0.533333333333333 0.0035288928098809
GO:BP GO:0032434 regulation of proteasomal ubiquitin-dependent protein catabolic process 0.0011046844357249 134 15 3 0.2 0.0223880597014925
GO:BP GO:0090304 nucleic acid metabolic process 0.00113081164354405 5226 16 12 0.75 0.00229621125143513
GO:BP GO:0015031 protein transport 0.00113081164354405 1929 85 21 0.247058823529412 0.0108864696734059
GO:BP GO:0071902 positive regulation of protein serine/threonine kinase activity 0.00113081164354405 316 7 3 0.428571428571429 0.00949367088607595
GO:BP GO:0048534 hematopoietic or lymphoid organ development 0.00116451427530175 966 57 11 0.192982456140351 0.0113871635610766
GO:BP GO:0010970 transport along microtubule 0.00122771994535106 164 32 4 0.125 0.024390243902439
GO:BP GO:0006886 intracellular protein transport 0.00123901715726706 1186 40 10 0.25 0.00843170320404722
GO:BP GO:0030097 hemopoiesis 0.00123998462201204 928 18 6 0.333333333333333 0.00646551724137931
GO:BP GO:0031348 negative regulation of defense response 0.00124569496791452 246 9 3 0.333333333333333 0.0121951219512195
GO:BP GO:0032273 positive regulation of protein polymerization 0.00124607204395649 141 15 3 0.2 0.0212765957446809
GO:BP GO:1903506 regulation of nucleic acid-templated transcription 0.0012569021445434 3535 16 10 0.625 0.00282885431400283
GO:BP GO:2001141 regulation of RNA biosynthetic process 0.00126967783119263 3540 16 10 0.625 0.00282485875706215
GO:BP GO:1903321 negative regulation of protein modification by small protein conjugation or removal 0.00130010342132149 96 22 3 0.136363636363636 0.03125
GO:BP GO:0044267 cellular protein metabolic process 0.00130626420633031 5229 53 28 0.528301886792453 0.00535475234270415
GO:BP GO:0044260 cellular macromolecule metabolic process 0.00133316405106795 8390 45 33 0.733333333333333 0.00393325387365912
GO:BP GO:0051239 regulation of multicellular organismal process 0.00137874478261401 2861 19 10 0.526315789473684 0.0034952813701503
GO:BP GO:2001239 regulation of extrinsic apoptotic signaling pathway in absence of ligand 0.00141900880807192 44 49 3 0.0612244897959184 0.0681818181818182
GO:BP GO:0097435 supramolecular fiber organization 0.00143204458865352 734 15 5 0.333333333333333 0.00681198910081744
GO:BP GO:0015833 peptide transport 0.00145929030623747 1971 85 21 0.247058823529412 0.0106544901065449
GO:BP GO:0002262 myeloid cell homeostasis 0.00147644627708745 151 15 3 0.2 0.0198675496688742
GO:BP GO:0051179 localization 0.00151590923781686 6901 35 24 0.685714285714286 0.00347775684683379
GO:BP GO:0006810 transport 0.00151590923781686 5224 82 39 0.475609756097561 0.00746554364471669
GO:BP GO:1903364 positive regulation of cellular protein catabolic process 0.00155005980477295 154 15 3 0.2 0.0194805194805195
GO:BP GO:0052126 movement in host environment 0.00155238278675117 177 32 4 0.125 0.0225988700564972
GO:BP GO:0006807 nitrogen compound metabolic process 0.00156658549494544 10078 47 38 0.808510638297872 0.00377058940265926
GO:BP GO:0050789 regulation of biological process 0.00156945927957085 12091 38 35 0.921052631578947 0.00289471507733025
GO:BP GO:2000026 regulation of multicellular organismal development 0.00161346261241902 1447 23 8 0.347826086956522 0.0055286800276434
GO:BP GO:0051129 negative regulation of cellular component organization 0.00161738287696853 759 15 5 0.333333333333333 0.00658761528326746
GO:BP GO:0051049 regulation of transport 0.00164382962956957 1809 50 14 0.28 0.00773908236594804
GO:BP GO:0051240 positive regulation of multicellular organismal process 0.00165703953144879 1455 23 8 0.347826086956522 0.00549828178694158
GO:BP GO:0019886 antigen processing and presentation of exogenous peptide antigen via MHC class II 0.00170099325713144 96 60 4 0.0666666666666667 0.0416666666666667
GO:BP GO:0002520 immune system development 0.00170351783235496 1020 57 11 0.192982456140351 0.0107843137254902
GO:BP GO:0042325 regulation of phosphorylation 0.00172005592147111 1431 9 5 0.555555555555556 0.00349406009783368
GO:BP GO:0060249 anatomical structure homeostasis 0.0017268195099155 482 23 5 0.217391304347826 0.0103734439834025
GO:BP GO:0042886 amide transport 0.00176121984039958 2007 85 21 0.247058823529412 0.0104633781763827
GO:BP GO:0097659 nucleic acid-templated transcription 0.00176976238842364 3715 16 10 0.625 0.00269179004037685
GO:BP GO:0097242 amyloid-beta clearance 0.00178973437345465 38 63 3 0.0476190476190476 0.0789473684210526
GO:BP GO:2000058 regulation of ubiquitin-dependent protein catabolic process 0.00179460573833583 165 15 3 0.2 0.0181818181818182
GO:BP GO:0032774 RNA biosynthetic process 0.00181092468823851 3731 16 10 0.625 0.00268024658268561
GO:BP GO:2000008 regulation of protein localization to cell surface 0.0018224987777938 39 62 3 0.0483870967741935 0.0769230769230769
GO:BP GO:0071705 nitrogen compound transport 0.00183961231818307 2322 85 23 0.270588235294118 0.0099052540913006
GO:BP GO:0051276 chromosome organization 0.00189431470834348 1258 3 3 1 0.00238473767885533
GO:BP GO:0002495 antigen processing and presentation of peptide antigen via MHC class II 0.00189501512630841 100 60 4 0.0666666666666667 0.04
GO:BP GO:0050684 regulation of mRNA processing 0.00189501512630841 158 16 3 0.1875 0.0189873417721519
GO:BP GO:0007417 central nervous system development 0.00189501512630841 1032 12 5 0.416666666666667 0.00484496124031008
GO:BP GO:0030099 myeloid cell differentiation 0.0019178586092382 428 15 4 0.266666666666667 0.00934579439252336
GO:BP GO:0017038 protein import 0.00194113038830555 205 30 4 0.133333333333333 0.0195121951219512
GO:BP GO:0035196 production of miRNAs involved in gene silencing by miRNA 0.00197641463539538 51 49 3 0.0612244897959184 0.0588235294117647
GO:BP GO:0002698 negative regulation of immune effector process 0.00200482164688886 125 49 4 0.0816326530612245 0.032
GO:BP GO:0071900 regulation of protein serine/threonine kinase activity 0.00200482164688886 503 23 5 0.217391304347826 0.0099403578528827
GO:BP GO:0002504 antigen processing and presentation of peptide or polysaccharide antigen via MHC class II 0.00207543778602161 103 25 3 0.12 0.029126213592233
GO:BP GO:0051234 establishment of localization 0.00208898106001558 5372 34 20 0.588235294117647 0.00372300819061802
GO:BP GO:0000723 telomere maintenance 0.002100278863255 165 16 3 0.1875 0.0181818181818182
GO:BP GO:0044087 regulation of cellular component biogenesis 0.00211729293099829 990 19 6 0.315789473684211 0.00606060606060606
GO:BP GO:0051252 regulation of RNA metabolic process 0.00213899376458827 3822 16 10 0.625 0.00261643118785976
GO:BP GO:0099111 microtubule-based transport 0.00214366137000556 198 32 4 0.125 0.0202020202020202
GO:BP GO:0060341 regulation of cellular localization 0.00219832255239125 851 49 9 0.183673469387755 0.0105757931844888
GO:BP GO:0070918 production of small RNA involved in gene silencing by RNA 0.00225752109999219 54 49 3 0.0612244897959184 0.0555555555555556
GO:BP GO:0031050 dsRNA processing 0.00225752109999219 54 49 3 0.0612244897959184 0.0555555555555556
GO:BP GO:0030705 cytoskeleton-dependent intracellular transport 0.00227274972559578 202 32 4 0.125 0.0198019801980198
GO:BP GO:0001959 regulation of cytokine-mediated signaling pathway 0.00230185013109731 184 15 3 0.2 0.016304347826087
GO:BP GO:0045732 positive regulation of protein catabolic process 0.00234833490216356 237 49 5 0.102040816326531 0.0210970464135021
GO:BP GO:0043254 regulation of protein-containing complex assembly 0.0023891014056504 460 15 4 0.266666666666667 0.00869565217391304
GO:BP GO:0006974 cellular response to DNA damage stimulus 0.00240636017053242 888 4 3 0.75 0.00337837837837838
GO:BP GO:0046631 alpha-beta T cell activation 0.00241732869550172 155 18 3 0.166666666666667 0.0193548387096774
GO:BP GO:0006139 nucleobase-containing compound metabolic process 0.00249267132709427 5746 16 12 0.75 0.00208840932822833
GO:BP GO:0032200 telomere organization 0.0025051998353839 178 16 3 0.1875 0.0168539325842697
GO:BP GO:0034976 response to endoplasmic reticulum stress 0.0025147823490034 298 40 5 0.125 0.0167785234899329
GO:BP GO:0033036 macromolecule localization 0.00251746218018537 3218 35 15 0.428571428571429 0.00466128029832194
GO:BP GO:0009617 response to bacterium 0.00252908860192862 743 10 4 0.4 0.0053835800807537
GO:BP GO:0036211 protein modification process 0.00256965341133802 4041 53 23 0.433962264150943 0.00569166048007919
GO:BP GO:0006464 cellular protein modification process 0.00256965341133802 4041 53 23 0.433962264150943 0.00569166048007919
GO:BP GO:0051248 negative regulation of protein metabolic process 0.00256965341133802 1151 54 11 0.203703703703704 0.00955690703735882
GO:BP GO:0071704 organic substance metabolic process 0.00257720206832242 11326 59 49 0.830508474576271 0.00432632880098887
GO:BP GO:2001238 positive regulation of extrinsic apoptotic signaling pathway 0.0026314281159357 48 59 3 0.0508474576271186 0.0625
GO:BP GO:0032757 positive regulation of interleukin-8 production 0.00265423073245742 58 49 3 0.0612244897959184 0.0517241379310345
GO:BP GO:0007018 microtubule-based movement 0.00265423073245742 383 32 5 0.15625 0.0130548302872063
GO:BP GO:0060759 regulation of response to cytokine stimulus 0.00267339572455563 197 15 3 0.2 0.0152284263959391
GO:BP GO:0016070 RNA metabolic process 0.00277975214265971 4710 44 22 0.5 0.00467091295116773
GO:BP GO:0019220 regulation of phosphate metabolic process 0.00285893021260812 1645 9 5 0.555555555555556 0.00303951367781155
GO:BP GO:0051174 regulation of phosphorus metabolic process 0.00285893021260812 1645 9 5 0.555555555555556 0.00303951367781155
GO:BP GO:0010559 regulation of glycoprotein biosynthetic process 0.00295395586464565 55 54 3 0.0555555555555556 0.0545454545454545
GO:BP GO:0016049 cell growth 0.00296275900181237 495 15 4 0.266666666666667 0.00808080808080808
GO:BP GO:0051701 biological process involved in interaction with host 0.00296434020409938 221 32 4 0.125 0.0180995475113122
GO:BP GO:0006468 protein phosphorylation 0.00301396784560078 1668 9 5 0.555555555555556 0.00299760191846523
GO:BP GO:0050793 regulation of developmental process 0.00303399005963391 2605 19 9 0.473684210526316 0.00345489443378119
GO:BP GO:0050852 T cell receptor signaling pathway 0.00303700751152494 203 35 4 0.114285714285714 0.0197044334975369
GO:BP GO:0046483 heterocycle metabolic process 0.00309832619491534 5904 16 12 0.75 0.00203252032520325
GO:BP GO:0061919 process utilizing autophagic mechanism 0.00310824104675209 543 24 5 0.208333333333333 0.00920810313075507
GO:BP GO:0006914 autophagy 0.00310824104675209 543 24 5 0.208333333333333 0.00920810313075507
GO:BP GO:0048513 animal organ development 0.00313481212535949 3672 12 8 0.666666666666667 0.00217864923747277
GO:BP GO:0031331 positive regulation of cellular catabolic process 0.00313481212535949 393 49 6 0.122448979591837 0.0152671755725191
GO:BP GO:0002700 regulation of production of molecular mediator of immune response 0.00313481212535949 148 21 3 0.142857142857143 0.0202702702702703
GO:BP GO:0007017 microtubule-based process 0.00314013651387906 881 23 6 0.260869565217391 0.00681044267877412
GO:BP GO:0010803 regulation of tumor necrosis factor-mediated signaling pathway 0.00319984493451802 63 49 3 0.0612244897959184 0.0476190476190476
GO:BP GO:0006725 cellular aromatic compound metabolic process 0.00328675828089633 5956 16 12 0.75 0.00201477501678979
GO:BP GO:0032879 regulation of localization 0.00328675828089633 2872 32 13 0.40625 0.00452646239554318
GO:BP GO:0051054 positive regulation of DNA metabolic process 0.00333933634497188 203 16 3 0.1875 0.0147783251231527
GO:BP GO:0043065 positive regulation of apoptotic process 0.00343392528935806 604 59 8 0.135593220338983 0.0132450331125828
GO:BP GO:0051050 positive regulation of transport 0.00344706507511366 923 49 9 0.183673469387755 0.00975081256771398
GO:BP GO:1903131 mononuclear cell differentiation 0.00348702052584355 430 18 4 0.222222222222222 0.00930232558139535
GO:BP GO:0009966 regulation of signal transduction 0.00363370189609798 3165 23 11 0.478260869565217 0.00347551342812006
GO:BP GO:0097191 extrinsic apoptotic signaling pathway 0.00366922837922165 223 59 5 0.0847457627118644 0.0224215246636771
GO:BP GO:0031400 negative regulation of protein modification process 0.00386096868262923 578 24 5 0.208333333333333 0.00865051903114187
GO:BP GO:1903018 regulation of glycoprotein metabolic process 0.0038618438467203 62 54 3 0.0555555555555556 0.0483870967741935
GO:BP GO:1905897 regulation of response to endoplasmic reticulum stress 0.00386493534750829 84 40 3 0.075 0.0357142857142857
GO:BP GO:0032102 negative regulation of response to external stimulus 0.00389682322684849 406 9 3 0.333333333333333 0.00738916256157635
GO:BP GO:0051130 positive regulation of cellular component organization 0.00395218368327042 1153 19 6 0.315789473684211 0.00520381613183001
GO:BP GO:0043068 positive regulation of programmed cell death 0.00395218368327042 621 59 8 0.135593220338983 0.0128824476650564
GO:BP GO:0034641 cellular nitrogen compound metabolic process 0.00401156707425136 6563 49 29 0.591836734693878 0.00441871095535578
GO:BP GO:0032271 regulation of protein polymerization 0.0040203224802397 236 15 3 0.2 0.0127118644067797
GO:BP GO:0030154 cell differentiation 0.00402145048025833 4350 11 8 0.727272727272727 0.00183908045977011
GO:BP GO:0002683 negative regulation of immune system process 0.00407784249659156 420 49 6 0.122448979591837 0.0142857142857143
GO:BP GO:0006665 sphingolipid metabolic process 0.00411152709931024 169 80 5 0.0625 0.029585798816568
GO:BP GO:0046907 intracellular transport 0.00417087234828989 1767 3 3 1 0.00169779286926995
GO:BP GO:0009605 response to external stimulus 0.00417791520223474 2944 18 9 0.5 0.0030570652173913
GO:BP GO:0097192 extrinsic apoptotic signaling pathway in absence of ligand 0.00417791520223474 71 49 3 0.0612244897959184 0.0422535211267606
GO:BP GO:0038034 signal transduction in absence of ligand 0.00417791520223474 71 49 3 0.0612244897959184 0.0422535211267606
GO:BP GO:1901564 organonitrogen compound metabolic process 0.00418082538445862 6792 54 32 0.592592592592593 0.00471142520612485
GO:BP GO:0048731 system development 0.00420192963154667 5052 12 9 0.75 0.00178147268408551
GO:BP GO:0071407 cellular response to organic cyclic compound 0.00423830170684436 587 49 7 0.142857142857143 0.0119250425894378
GO:BP GO:0044249 cellular biosynthetic process 0.00423830170684436 6154 16 12 0.75 0.00194995125121872
GO:BP GO:0007041 lysosomal transport 0.00431651127346614 111 32 3 0.09375 0.027027027027027
GO:BP GO:0010557 positive regulation of macromolecule biosynthetic process 0.00433081521419169 1851 9 5 0.555555555555556 0.00270124257158293
GO:BP GO:1902115 regulation of organelle assembly 0.00439269114470842 192 19 3 0.157894736842105 0.015625
GO:BP GO:0048869 cellular developmental process 0.00440767674494676 4428 11 8 0.727272727272727 0.001806684733514
GO:BP GO:0051094 positive regulation of developmental process 0.00446802884996828 1341 23 7 0.304347826086957 0.0052199850857569
GO:BP GO:0032436 positive regulation of proteasomal ubiquitin-dependent protein catabolic process 0.0044750371198241 90 40 3 0.075 0.0333333333333333
GO:BP GO:1901360 organic cyclic compound metabolic process 0.00450290551384945 6201 16 12 0.75 0.0019351717464925
GO:BP GO:0032880 regulation of protein localization 0.00454057581699815 922 24 6 0.25 0.00650759219088937
GO:BP GO:0062197 cellular response to chemical stress 0.00459594099422767 365 23 4 0.173913043478261 0.010958904109589
GO:BP GO:0043412 macromolecule modification 0.00465442977085355 4257 53 23 0.433962264150943 0.00540286586798215
GO:BP GO:0071495 cellular response to endogenous stimulus 0.00471531818196671 1422 7 4 0.571428571428571 0.00281293952180028
GO:BP GO:1901576 organic substance biosynthetic process 0.00477466693019502 6248 16 12 0.75 0.00192061459667093
GO:BP GO:0043269 regulation of ion transport 0.0047780543545694 1379 50 11 0.22 0.00797679477882524
GO:BP GO:0009968 negative regulation of signal transduction 0.00478649931091662 1364 23 7 0.304347826086957 0.00513196480938416
GO:BP GO:0048872 homeostasis of number of cells 0.00495701041832256 261 15 3 0.2 0.0114942528735632
GO:BP GO:0042110 T cell activation 0.0049673234302905 489 18 4 0.222222222222222 0.0081799591002045
GO:BP GO:0031334 positive regulation of protein-containing complex assembly 0.005052330409376 263 15 3 0.2 0.0114068441064639
GO:BP GO:0006355 regulation of transcription, DNA-templated 0.00506866931422438 3534 16 9 0.5625 0.00254668930390492
GO:BP GO:0050870 positive regulation of T cell activation 0.00516401686753581 219 18 3 0.166666666666667 0.0136986301369863
GO:BP GO:0031328 positive regulation of cellular biosynthetic process 0.00528928707438781 1967 3 3 1 0.00152516522623284
GO:BP GO:0009058 biosynthetic process 0.00532163994994283 6340 16 12 0.75 0.00189274447949527
GO:BP GO:0014070 response to organic cyclic compound 0.00536831086598941 967 82 12 0.146341463414634 0.0124095139607032
GO:BP GO:0061462 protein localization to lysosome 0.00536831086598941 46 85 3 0.0352941176470588 0.0652173913043478
GO:BP GO:0033209 tumor necrosis factor-mediated signaling pathway 0.00537481956510187 177 49 4 0.0816326530612245 0.0225988700564972
GO:BP GO:0002833 positive regulation of response to biotic stimulus 0.00537481956510187 250 35 4 0.114285714285714 0.016
GO:BP GO:0045597 positive regulation of cell differentiation 0.0054374703840825 879 18 5 0.277777777777778 0.00568828213879408
GO:BP GO:0009891 positive regulation of biosynthetic process 0.00547003274975969 2004 3 3 1 0.00149700598802395
GO:BP GO:0065007 biological regulation 0.00560992078671082 12809 38 35 0.921052631578947 0.00273245374346163
GO:BP GO:0010646 regulation of cell communication 0.00586947719782976 3543 4 4 1 0.00112898673440587
GO:BP GO:0034394 protein localization to cell surface 0.00598557975575231 66 62 3 0.0483870967741935 0.0454545454545455
GO:BP GO:0043393 regulation of protein binding 0.00598711914911177 199 21 3 0.142857142857143 0.0150753768844221
GO:BP GO:0009896 positive regulation of catabolic process 0.00599046175568482 464 49 6 0.122448979591837 0.0129310344827586
GO:BP GO:0023051 regulation of signaling 0.00603666014554963 3578 4 4 1 0.00111794298490777
GO:BP GO:0045445 myoblast differentiation 0.00603666014554963 84 49 3 0.0612244897959184 0.0357142857142857
GO:BP GO:0048812 neuron projection morphogenesis 0.00609407016668281 664 7 3 0.428571428571429 0.00451807228915663
GO:BP GO:0031175 neuron projection development 0.00612091143561173 1012 10 4 0.4 0.00395256916996047
GO:BP GO:0006811 ion transport 0.00612091143561173 3661 62 23 0.370967741935484 0.00628243649276154
GO:BP GO:0010942 positive regulation of cell death 0.00631822233159703 684 59 8 0.135593220338983 0.0116959064327485
GO:BP GO:0120039 plasma membrane bounded cell projection morphogenesis 0.0064102954207499 678 7 3 0.428571428571429 0.00442477876106195
GO:BP GO:1903039 positive regulation of leukocyte cell-cell adhesion 0.0064214518865397 241 18 3 0.166666666666667 0.012448132780083
GO:BP GO:0016310 phosphorylation 0.00643220331942757 2138 3 3 1 0.00140318054256314
GO:BP GO:0048858 cell projection morphogenesis 0.0064576509325787 682 7 3 0.428571428571429 0.00439882697947214
GO:BP GO:0051098 regulation of binding 0.0064576509325787 365 63 6 0.0952380952380952 0.0164383561643836
GO:BP GO:0051254 positive regulation of RNA metabolic process 0.0064576509325787 1714 49 12 0.244897959183673 0.00700116686114352
GO:BP GO:2000060 positive regulation of ubiquitin-dependent protein catabolic process 0.00656100153631865 107 40 3 0.075 0.0280373831775701
GO:BP GO:0019725 cellular homeostasis 0.00662980941632523 981 62 10 0.161290322580645 0.0101936799184506
GO:BP GO:0010648 negative regulation of cell communication 0.00671431134316841 1468 23 7 0.304347826086957 0.00476839237057221
GO:BP GO:0023057 negative regulation of signaling 0.00678114776475414 1471 23 7 0.304347826086957 0.00475866757307954
GO:BP GO:0006351 transcription, DNA-templated 0.00678114776475414 3714 16 9 0.5625 0.0024232633279483
GO:BP GO:0044237 cellular metabolic process 0.00680724072226605 10871 54 43 0.796296296296296 0.00395547787692025
GO:BP GO:0032990 cell part morphogenesis 0.00681461594817877 699 7 3 0.428571428571429 0.00429184549356223
GO:BP GO:0030900 forebrain development 0.0069353760012363 385 12 3 0.25 0.00779220779220779
GO:BP GO:0002521 leukocyte differentiation 0.0069745750140762 550 18 4 0.222222222222222 0.00727272727272727
GO:BP GO:0051258 protein polymerization 0.00703571175464294 305 15 3 0.2 0.00983606557377049
GO:BP GO:0038061 NIK/NF-kappaB signaling 0.00704049552153043 194 49 4 0.0816326530612245 0.0206185567010309
GO:BP GO:0051128 regulation of cellular component organization 0.00712926531190092 2412 19 8 0.421052631578947 0.0033167495854063
GO:BP GO:1901800 positive regulation of proteasomal protein catabolic process 0.00721691698728737 112 40 3 0.075 0.0267857142857143
GO:BP GO:0043410 positive regulation of MAPK cascade 0.00721691698728737 539 9 3 0.333333333333333 0.00556586270871985
GO:BP GO:0046034 ATP metabolic process 0.0074650259737997 314 15 3 0.2 0.00955414012738853
GO:BP GO:0030217 T cell differentiation 0.00753844127934857 260 18 3 0.166666666666667 0.0115384615384615
GO:BP GO:0008152 metabolic process 0.00758357226521282 11827 59 49 0.830508474576271 0.00414306248414644
GO:BP GO:0009719 response to endogenous stimulus 0.00761363924993795 1683 7 4 0.571428571428571 0.0023767082590612
GO:BP GO:0006413 translational initiation 0.0077413276688611 201 49 4 0.0816326530612245 0.0199004975124378
GO:BP GO:0044089 positive regulation of cellular component biogenesis 0.00776442481725332 540 19 4 0.210526315789474 0.00740740740740741
GO:BP GO:0007275 multicellular organism development 0.00793590970525845 5613 12 9 0.75 0.00160342063067878
GO:BP GO:0032269 negative regulation of cellular protein metabolic process 0.00803255249756436 1082 49 9 0.183673469387755 0.00831792975970425
GO:BP GO:0007049 cell cycle 0.0081477570826917 1902 19 7 0.368421052631579 0.00368033648790747
GO:BP GO:0055080 cation homeostasis 0.00842231446689876 750 45 7 0.155555555555556 0.00933333333333333
GO:BP GO:0032677 regulation of interleukin-8 production 0.00864161100826462 99 49 3 0.0612244897959184 0.0303030303030303
GO:BP GO:0002377 immunoglobulin production 0.00864161100826462 99 49 3 0.0612244897959184 0.0303030303030303
GO:BP GO:0051100 negative regulation of binding 0.00864161100826462 163 30 3 0.1 0.0184049079754601
GO:BP GO:0002285 lymphocyte activation involved in immune response 0.0087322606766061 190 54 4 0.0740740740740741 0.0210526315789474
GO:BP GO:0051726 regulation of cell cycle 0.00875064772190089 1236 15 5 0.333333333333333 0.0040453074433657
GO:BP GO:0048666 neuron development 0.00875826323388725 1149 10 4 0.4 0.00348128807658834
GO:BP GO:0032103 positive regulation of response to external stimulus 0.00877772896392731 513 49 6 0.122448979591837 0.0116959064327485
GO:BP GO:0007034 vacuolar transport 0.00877772896392731 154 32 3 0.09375 0.0194805194805195
GO:BP GO:0098771 inorganic ion homeostasis 0.00884839281121196 761 45 7 0.155555555555556 0.00919842312746386
GO:BP GO:0032989 cellular component morphogenesis 0.00888614743852045 791 7 3 0.428571428571429 0.00379266750948167
GO:BP GO:0043401 steroid hormone mediated signaling pathway 0.00901550827883204 140 74 4 0.0540540540540541 0.0285714285714286
GO:BP GO:0022409 positive regulation of cell-cell adhesion 0.00908388761270317 284 18 3 0.166666666666667 0.0105633802816901
GO:BP GO:0030162 regulation of proteolysis 0.00921814579942839 752 24 5 0.208333333333333 0.00664893617021277
GO:BP GO:1902105 regulation of leukocyte differentiation 0.00925837357127092 288 18 3 0.166666666666667 0.0104166666666667
GO:BP GO:0006643 membrane lipid metabolic process 0.0092863788006481 217 80 5 0.0625 0.0230414746543779
GO:BP GO:0022402 cell cycle process 0.0092863788006481 1439 19 6 0.315789473684211 0.00416956219596942
GO:BP GO:0032637 interleukin-8 production 0.00944232134963592 104 49 3 0.0612244897959184 0.0288461538461538
GO:BP GO:0030518 intracellular steroid hormone receptor signaling pathway 0.00950087587089211 119 43 3 0.0697674418604651 0.0252100840336134
GO:BP GO:0031349 positive regulation of defense response 0.00966926072473846 362 49 5 0.102040816326531 0.0138121546961326
GO:BP GO:0042982 amyloid precursor protein metabolic process 0.00984092414403841 96 54 3 0.0555555555555556 0.03125
GO:BP GO:1903052 positive regulation of proteolysis involved in cellular protein catabolic process 0.00996488500460267 131 40 3 0.075 0.0229007633587786
GO:BP GO:0048545 response to steroid hormone 0.0100045779163147 349 74 6 0.0810810810810811 0.0171919770773639
GO:BP GO:2001237 negative regulation of extrinsic apoptotic signaling pathway 0.0102739341997484 108 49 3 0.0612244897959184 0.0277777777777778
GO:BP GO:0010638 positive regulation of organelle organization 0.0104184232180953 603 19 4 0.210526315789474 0.0066334991708126
GO:BP GO:0043408 regulation of MAPK cascade 0.0107910193221294 730 49 7 0.142857142857143 0.00958904109589041
GO:BP GO:1903827 regulation of cellular protein localization 0.0107910193221294 572 62 7 0.112903225806452 0.0122377622377622
GO:BP GO:0008285 negative regulation of cell population proliferation 0.0108537223939418 790 15 4 0.266666666666667 0.00506329113924051
GO:BP GO:0000165 MAPK cascade 0.0108944029804339 935 49 8 0.163265306122449 0.00855614973262032
GO:BP GO:0050851 antigen receptor-mediated signaling pathway 0.0109163469508808 323 35 4 0.114285714285714 0.0123839009287926
GO:BP GO:0071702 organic substance transport 0.010947414281569 2766 75 21 0.28 0.00759219088937093
GO:BP GO:0050801 ion homeostasis 0.0113869496785447 808 45 7 0.155555555555556 0.00866336633663366
GO:BP GO:0000398 mRNA splicing, via spliceosome 0.0116048875212247 361 16 3 0.1875 0.00831024930747922
GO:BP GO:0000377 RNA splicing, via transesterification reactions with bulged adenosine as nucleophile 0.0116048875212247 361 16 3 0.1875 0.00831024930747922
GO:BP GO:0010564 regulation of cell cycle process 0.011613346334961 809 15 4 0.266666666666667 0.00494437577255871
GO:BP GO:1902903 regulation of supramolecular fiber organization 0.0116154312655387 387 15 3 0.2 0.00775193798449612
GO:BP GO:0019079 viral genome replication 0.0116627890288995 131 87 4 0.0459770114942529 0.0305343511450382
GO:BP GO:0051052 regulation of DNA metabolic process 0.0117204197735178 363 16 3 0.1875 0.00826446280991736
GO:BP GO:0000375 RNA splicing, via transesterification reactions 0.0117850191308555 364 16 3 0.1875 0.00824175824175824
GO:BP GO:0050792 regulation of viral process 0.011817078429928 192 97 5 0.0515463917525773 0.0260416666666667
GO:BP GO:0051251 positive regulation of lymphocyte activation 0.0118324126905938 365 32 4 0.125 0.010958904109589
GO:BP GO:0072655 establishment of protein localization to mitochondrion 0.0121118665873911 143 40 3 0.075 0.020979020979021
GO:BP GO:0006820 anion transport 0.0125518135076571 2889 3 3 1 0.00103842159916926
GO:BP GO:0070585 protein localization to mitochondrion 0.0127765651372415 147 40 3 0.075 0.0204081632653061
GO:BP GO:0048856 anatomical structure development 0.0128598006787563 6106 12 9 0.75 0.0014739600393056
GO:BP GO:0050863 regulation of T cell activation 0.01296491937762 337 18 3 0.166666666666667 0.00890207715133531
GO:BP GO:1903037 regulation of leukocyte cell-cell adhesion 0.0130447525920988 338 18 3 0.166666666666667 0.00887573964497041
GO:BP GO:0043666 regulation of phosphoprotein phosphatase activity 0.0130625194910304 121 49 3 0.0612244897959184 0.0247933884297521
GO:BP GO:0016043 cellular component organization 0.0133269363614808 6566 19 13 0.684210526315789 0.00197989643618641
GO:BP GO:0055082 cellular chemical homeostasis 0.0133682246912672 841 45 7 0.155555555555556 0.00832342449464923
GO:BP GO:0071396 cellular response to lipid 0.0135326857079501 578 49 6 0.122448979591837 0.0103806228373702
GO:BP GO:0072665 protein localization to vacuole 0.0136395323762722 71 85 3 0.0352941176470588 0.0422535211267606
GO:BP GO:0051223 regulation of protein transport 0.013835408744537 586 81 8 0.0987654320987654 0.0136518771331058
GO:BP GO:1902532 negative regulation of intracellular signal transduction 0.0139219899377996 549 23 4 0.173913043478261 0.00728597449908925
GO:BP GO:0032091 negative regulation of protein binding 0.0139464833245334 97 63 3 0.0476190476190476 0.0309278350515464
GO:BP GO:0007040 lysosome organization 0.0139627580018817 72 85 3 0.0352941176470588 0.0416666666666667
GO:BP GO:0080171 lytic vacuole organization 0.0139627580018817 72 85 3 0.0352941176470588 0.0416666666666667
GO:BP GO:0044092 negative regulation of molecular function 0.0144569020661591 1219 49 9 0.183673469387755 0.007383100902379
GO:BP GO:0006796 phosphate-containing compound metabolic process 0.0145524788038643 3087 3 3 1 0.000971817298347911
GO:BP GO:0006357 regulation of transcription by RNA polymerase II 0.0145940319137487 2555 43 13 0.302325581395349 0.0050880626223092
GO:BP GO:0006793 phosphorus metabolic process 0.014830484910052 3114 3 3 1 0.000963391136801541
GO:BP GO:0030182 neuron differentiation 0.0153258226937098 1412 10 4 0.4 0.0028328611898017
GO:BP GO:0060627 regulation of vesicle-mediated transport 0.0155213898773629 536 72 7 0.0972222222222222 0.0130597014925373
GO:BP GO:0000280 nuclear division 0.0156678072160857 448 15 3 0.2 0.00669642857142857
GO:BP GO:0000902 cell morphogenesis 0.0157173075288179 1037 7 3 0.428571428571429 0.00289296046287367
GO:BP GO:0007159 leukocyte cell-cell adhesion 0.0161879476392205 375 18 3 0.166666666666667 0.008
GO:BP GO:0002696 positive regulation of leukocyte activation 0.0162563211849767 412 32 4 0.125 0.00970873786407767
GO:BP GO:0030098 lymphocyte differentiation 0.0162754576289408 376 18 3 0.166666666666667 0.00797872340425532
GO:BP GO:0070201 regulation of establishment of protein localization 0.0163311698588153 611 22 4 0.181818181818182 0.00654664484451719
GO:BP GO:0045667 regulation of osteoblast differentiation 0.0163779514764169 135 49 3 0.0612244897959184 0.0222222222222222
GO:BP GO:0071840 cellular component organization or biogenesis 0.0165076586387773 6760 19 13 0.684210526315789 0.00192307692307692
GO:BP GO:0006898 receptor-mediated endocytosis 0.0167809234766675 333 63 5 0.0793650793650794 0.015015015015015
GO:BP GO:0090087 regulation of peptide transport 0.0168253135751544 618 22 4 0.181818181818182 0.00647249190938511
GO:BP GO:0030003 cellular cation homeostasis 0.0170452544358318 673 45 6 0.133333333333333 0.00891530460624071
GO:BP GO:0051348 negative regulation of transferase activity 0.0171325506563452 310 43 4 0.0930232558139535 0.0129032258064516
GO:BP GO:0046649 lymphocyte activation 0.0171565836888812 771 18 4 0.222222222222222 0.00518806744487678
GO:BP GO:0032501 multicellular organismal process 0.0174276474333397 7946 12 10 0.833333333333333 0.00125849484017116
GO:BP GO:0050867 positive regulation of cell activation 0.0174683650665987 424 32 4 0.125 0.00943396226415094
GO:BP GO:0006970 response to osmotic stress 0.0174683650665987 84 81 3 0.037037037037037 0.0357142857142857
GO:BP GO:0044070 regulation of anion transport 0.0178598719885166 896 81 10 0.123456790123457 0.0111607142857143
GO:BP GO:0006873 cellular ion homeostasis 0.0184033025730718 687 45 6 0.133333333333333 0.00873362445414847
GO:BP GO:0040007 growth 0.0187015290646627 967 15 4 0.266666666666667 0.00413650465356774
GO:BP GO:0048259 regulation of receptor-mediated endocytosis 0.0189261776653075 112 63 3 0.0476190476190476 0.0267857142857143
GO:BP GO:0034599 cellular response to oxidative stress 0.0194102640466559 316 23 3 0.130434782608696 0.00949367088607595
GO:BP GO:0035304 regulation of protein dephosphorylation 0.0194374250265207 146 49 3 0.0612244897959184 0.0205479452054795
GO:BP GO:0043122 regulation of I-kappaB kinase/NF-kappaB signaling 0.0194374250265207 251 87 5 0.0574712643678161 0.0199203187250996
GO:BP GO:0048285 organelle fission 0.019605259929346 497 15 3 0.2 0.00603621730382294
GO:BP GO:0048699 generation of neurons 0.0200980945237672 1559 10 4 0.4 0.00256574727389352
GO:BP GO:0120036 plasma membrane bounded cell projection organization 0.0204844853154885 1569 10 4 0.4 0.00254939451880178
GO:BP GO:0045069 regulation of viral genome replication 0.0205102632339421 84 87 3 0.0344827586206897 0.0357142857142857
GO:BP GO:0032502 developmental process 0.0208402835503731 6628 12 9 0.75 0.00135787567893784
GO:BP GO:0051336 regulation of hydrolase activity 0.0214593420162219 1321 49 9 0.183673469387755 0.00681302043906132
GO:BP GO:0045089 positive regulation of innate immune response 0.0215472273410922 216 35 3 0.0857142857142857 0.0138888888888889
GO:BP GO:0030030 cell projection organization 0.0218138242769846 1609 10 4 0.4 0.00248601615910503
GO:BP GO:0050890 cognition 0.0219778340124609 298 49 4 0.0816326530612245 0.0134228187919463
GO:BP GO:0006366 transcription by RNA polymerase II 0.0220669623527354 2723 43 13 0.302325581395349 0.00477414616232097
GO:BP GO:0032886 regulation of microtubule-based process 0.0221143547522862 240 32 3 0.09375 0.0125
GO:BP GO:0045785 positive regulation of cell adhesion 0.0223733233584289 437 18 3 0.166666666666667 0.0068649885583524
GO:BP GO:1903708 positive regulation of hemopoiesis 0.0225063188442294 157 49 3 0.0612244897959184 0.0191082802547771
GO:BP GO:1902107 positive regulation of leukocyte differentiation 0.0225063188442294 157 49 3 0.0612244897959184 0.0191082802547771
GO:BP GO:0016485 protein processing 0.0225458166656756 235 33 3 0.0909090909090909 0.0127659574468085
GO:BP GO:0022407 regulation of cell-cell adhesion 0.023215799651365 445 18 3 0.166666666666667 0.00674157303370787
GO:BP GO:0071356 cellular response to tumor necrosis factor 0.023594360351925 306 49 4 0.0816326530612245 0.0130718954248366
GO:BP GO:0009306 protein secretion 0.0236997394271547 384 85 6 0.0705882352941176 0.015625
GO:BP GO:0009755 hormone-mediated signaling pathway 0.0237466780256386 202 74 4 0.0540540540540541 0.0198019801980198
GO:BP GO:0035592 establishment of protein localization to extracellular region 0.0238800240327912 385 85 6 0.0705882352941176 0.0155844155844156
GO:BP GO:0022008 neurogenesis 0.0243708441951497 1675 10 4 0.4 0.00238805970149254
GO:BP GO:0048878 chemical homeostasis 0.024973904694861 1229 45 8 0.177777777777778 0.0065093572009764
GO:BP GO:0071692 protein localization to extracellular region 0.0255398387529674 392 85 6 0.0705882352941176 0.0153061224489796
GO:BP GO:0032675 regulation of interleukin-6 production 0.0261353568491686 168 49 3 0.0612244897959184 0.0178571428571429
GO:BP GO:0006397 mRNA processing 0.0262132013037305 532 16 3 0.1875 0.0056390977443609
GO:BP GO:0043270 positive regulation of ion transport 0.0262968713928416 694 49 6 0.122448979591837 0.00864553314121038
GO:BP GO:0051249 regulation of lymphocyte activation 0.0263898186788823 518 47 5 0.106382978723404 0.00965250965250965
GO:BP GO:0071383 cellular response to steroid hormone stimulus 0.026391041734414 210 74 4 0.0540540540540541 0.019047619047619
GO:BP GO:0006672 ceramide metabolic process 0.0267686699985377 104 80 3 0.0375 0.0288461538461538
GO:BP GO:0033993 response to lipid 0.0272900201562137 918 49 7 0.142857142857143 0.00762527233115468
GO:BP GO:0032635 interleukin-6 production 0.0273484762775348 172 49 3 0.0612244897959184 0.0174418604651163
GO:BP GO:1903793 positive regulation of anion transport 0.0275955286082519 504 49 5 0.102040816326531 0.00992063492063492
GO:BP GO:0006996 organelle organization 0.0279472401291561 4104 3 3 1 0.000730994152046784
GO:BP GO:0042127 regulation of cell population proliferation 0.0279478468070918 1774 15 5 0.333333333333333 0.0028184892897407
GO:BP GO:0003006 developmental process involved in reproduction 0.0281996649459082 982 26 5 0.192307692307692 0.00509164969450102
GO:BP GO:0007420 brain development 0.0284953920242796 754 12 3 0.25 0.00397877984084881
GO:BP GO:0043123 positive regulation of I-kappaB kinase/NF-kappaB signaling 0.0289304518378534 185 87 4 0.0459770114942529 0.0216216216216216
GO:BP GO:0034612 response to tumor necrosis factor 0.0289437568969465 331 49 4 0.0816326530612245 0.0120845921450151
GO:BP GO:0018193 peptidyl-amino acid modification 0.0296602029354793 1303 53 9 0.169811320754717 0.0069071373752878
GO:BP GO:0070925 organelle assembly 0.0298036662233284 895 19 4 0.210526315789474 0.00446927374301676
GO:BP GO:0010921 regulation of phosphatase activity 0.029854757659825 180 49 3 0.0612244897959184 0.0166666666666667
GO:BP GO:0051235 maintenance of location 0.0302646496612864 337 49 4 0.0816326530612245 0.0118694362017804
GO:BP GO:0060322 head development 0.0312627566927274 798 45 6 0.133333333333333 0.0075187969924812
GO:BP GO:0051345 positive regulation of hydrolase activity 0.0314413276008424 783 22 4 0.181818181818182 0.00510855683269476
GO:BP GO:0002790 peptide secretion 0.0326151491205479 421 85 6 0.0705882352941176 0.0142517814726841
GO:BP GO:0055065 metal ion homeostasis 0.0343315993481606 667 40 5 0.125 0.00749625187406297
GO:BP GO:0032386 regulation of intracellular transport 0.0346903330364256 367 72 5 0.0694444444444444 0.0136239782016349
GO:BP GO:0007399 nervous system development 0.0351930007160699 2449 12 5 0.416666666666667 0.00204164965291956
GO:BP GO:0002237 response to molecule of bacterial origin 0.03621508385068 361 49 4 0.0816326530612245 0.0110803324099723
GO:BP GO:0030073 insulin secretion 0.0366370793545795 218 81 4 0.0493827160493827 0.018348623853211
GO:BP GO:0051604 protein maturation 0.0391086706746772 306 33 3 0.0909090909090909 0.00980392156862745
GO:BP GO:0034504 protein localization to nucleus 0.0393742283463273 289 35 3 0.0857142857142857 0.0103806228373702
GO:BP GO:0045862 positive regulation of proteolysis 0.0407406672070691 378 49 4 0.0816326530612245 0.0105820105820106
GO:BP GO:0016042 lipid catabolic process 0.0411516727259737 349 80 5 0.0625 0.0143266475644699
GO:BP GO:0009101 glycoprotein biosynthetic process 0.0420727927100226 347 54 4 0.0740740740740741 0.0115273775216138
GO:BP GO:0009100 glycoprotein metabolic process 0.0424343351808356 424 91 6 0.0659340659340659 0.0141509433962264
GO:BP GO:0006913 nucleocytoplasmic transport 0.043106034124803 354 30 3 0.1 0.00847457627118644
GO:BP GO:0002694 regulation of leukocyte activation 0.0431403240795373 610 47 5 0.106382978723404 0.00819672131147541
GO:BP GO:0006979 response to oxidative stress 0.0431936901041099 466 23 3 0.130434782608696 0.00643776824034335
GO:BP GO:0043523 regulation of neuron apoptotic process 0.0434867541057794 216 49 3 0.0612244897959184 0.0138888888888889
GO:BP GO:0051169 nuclear transport 0.0437741827784778 357 30 3 0.1 0.00840336134453781
GO:BP GO:0035303 regulation of dephosphorylation 0.0438713015801953 217 49 3 0.0612244897959184 0.0138248847926267
GO:BP GO:0043086 negative regulation of catalytic activity 0.0441176238168188 851 23 4 0.173913043478261 0.00470035252643948
GO:BP GO:0008283 cell population proliferation 0.0442951301327433 2054 15 5 0.333333333333333 0.00243427458617332
GO:BP GO:0048468 cell development 0.0444595206719146 2100 10 4 0.4 0.0019047619047619
GO:BP GO:0006469 negative regulation of protein kinase activity 0.0448796657992703 251 43 3 0.0697674418604651 0.0119521912350598
GO:BP GO:0048871 multicellular organismal homeostasis 0.0455752976555774 530 55 5 0.0909090909090909 0.00943396226415094
GO:BP GO:0051241 negative regulation of multicellular organismal process 0.0461414180232229 1160 10 3 0.3 0.00258620689655172
GO:BP GO:0050803 regulation of synapse structure or activity 0.0461417680571662 223 49 3 0.0612244897959184 0.0134529147982063
GO:BP GO:0006367 transcription initiation from RNA polymerase II promoter 0.0463275258944766 200 97 4 0.0412371134020619 0.02
GO:BP GO:0023061 signal release 0.0479166613691339 496 81 6 0.0740740740740741 0.0120967741935484
GO:BP GO:0098609 cell-cell adhesion 0.049526589456577 894 23 4 0.173913043478261 0.00447427293064877
GO:BP GO:0001649 osteoblast differentiation 0.0497111053996284 232 49 3 0.0612244897959184 0.0129310344827586
GO:CC GO:0070062 extracellular exosome 2.21983244973508e-13 2176 39 26 0.666666666666667 0.0119485294117647
GO:CC GO:1903561 extracellular vesicle 2.21983244973508e-13 2261 39 26 0.666666666666667 0.011499336576736
GO:CC GO:0043230 extracellular organelle 2.21983244973508e-13 2263 39 26 0.666666666666667 0.0114891736632788
GO:CC GO:0030139 endocytic vesicle 1.65508204082396e-12 306 38 13 0.342105263157895 0.042483660130719
GO:CC GO:0042611 MHC protein complex 3.44652606513559e-12 24 18 6 0.333333333333333 0.25
GO:CC GO:0098576 lumenal side of membrane 2.35188058975714e-11 33 18 6 0.333333333333333 0.181818181818182
GO:CC GO:0010008 endosome membrane 2.61211912360026e-11 505 38 14 0.368421052631579 0.0277227722772277
GO:CC GO:0030666 endocytic vesicle membrane 4.6854708358439e-11 159 18 8 0.444444444444444 0.050314465408805
GO:CC GO:0005615 extracellular space 1.82374746122143e-10 3594 27 22 0.814814814814815 0.00612131329994435
GO:CC GO:0031982 vesicle 2.87379707398388e-10 4055 40 29 0.725 0.00715166461159063
GO:CC GO:0071556 integral component of lumenal side of endoplasmic reticulum membrane 3.53685270047601e-10 25 40 6 0.15 0.24
GO:CC GO:0098553 lumenal side of endoplasmic reticulum membrane 3.53685270047601e-10 25 40 6 0.15 0.24
GO:CC GO:0012507 ER to Golgi transport vesicle membrane 3.53685270047601e-10 57 18 6 0.333333333333333 0.105263157894737
GO:CC GO:0005768 endosome 6.23517405433517e-10 987 38 16 0.421052631578947 0.0162107396149949
GO:CC GO:0031410 cytoplasmic vesicle 7.42294200965646e-10 2424 40 23 0.575 0.00948844884488449
GO:CC GO:0097708 intracellular vesicle 7.42294200965646e-10 2428 40 23 0.575 0.00947281713344316
GO:CC GO:0042612 MHC class I protein complex 8.15669821961368e-10 8 17 4 0.235294117647059 0.5
GO:CC GO:0101002 ficolin-1-rich granule 2.58102354991303e-09 184 39 9 0.230769230769231 0.0489130434782609
GO:CC GO:0005764 lysosome 2.85790616967813e-09 712 91 20 0.21978021978022 0.0280898876404494
GO:CC GO:0000323 lytic vacuole 2.85790616967813e-09 712 91 20 0.21978021978022 0.0280898876404494
GO:CC GO:0030662 coated vesicle membrane 3.42304042006587e-09 177 18 7 0.388888888888889 0.0395480225988701
GO:CC GO:0005773 vacuole 3.45001579479008e-09 810 91 21 0.230769230769231 0.0259259259259259
GO:CC GO:0030134 COPII-coated ER to Golgi transport vesicle 3.45001579479008e-09 90 18 6 0.333333333333333 0.0666666666666667
GO:CC GO:0005576 extracellular region 8.41336265703448e-09 4567 25 21 0.84 0.00459820451061966
GO:CC GO:0030176 integral component of endoplasmic reticulum membrane 2.14380794232749e-08 158 40 8 0.2 0.0506329113924051
GO:CC GO:0098588 bounding membrane of organelle 2.35315448209361e-08 2158 85 31 0.364705882352941 0.0143651529193698
GO:CC GO:0031227 intrinsic component of endoplasmic reticulum membrane 2.93735690645295e-08 166 40 8 0.2 0.0481927710843374
GO:CC GO:0031301 integral component of organelle membrane 7.77601295523079e-08 382 40 10 0.25 0.0261780104712042
GO:CC GO:0030135 coated vesicle 8.45689805165667e-08 295 18 7 0.388888888888889 0.023728813559322
GO:CC GO:1904813 ficolin-1-rich granule lumen 8.45689805165667e-08 124 39 7 0.179487179487179 0.0564516129032258
GO:CC GO:0043202 lysosomal lumen 1.08569492025138e-07 97 80 8 0.1 0.0824742268041237
GO:CC GO:0045335 phagocytic vesicle 1.29475730257471e-07 137 38 7 0.184210526315789 0.0510948905109489
GO:CC GO:0031300 intrinsic component of organelle membrane 1.38838250508322e-07 413 40 10 0.25 0.0242130750605327
GO:CC GO:0030659 cytoplasmic vesicle membrane 1.4660462884691e-07 779 18 9 0.5 0.0115532734274711
GO:CC GO:0012506 vesicle membrane 1.79484245920315e-07 800 18 9 0.5 0.01125
GO:CC GO:0048770 pigment granule 1.88663621564254e-07 105 81 8 0.0987654320987654 0.0761904761904762
GO:CC GO:0042470 melanosome 1.88663621564254e-07 105 81 8 0.0987654320987654 0.0761904761904762
GO:CC GO:0005789 endoplasmic reticulum membrane 3.09315550636948e-07 1117 52 16 0.307692307692308 0.0143240823634736
GO:CC GO:0030658 transport vesicle membrane 3.12817686998429e-07 209 18 6 0.333333333333333 0.0287081339712919
GO:CC GO:0098827 endoplasmic reticulum subcompartment 3.12817686998429e-07 1122 52 16 0.307692307692308 0.0142602495543672
GO:CC GO:0042175 nuclear outer membrane-endoplasmic reticulum membrane network 3.76605145125475e-07 1139 52 16 0.307692307692308 0.0140474100087796
GO:CC GO:0012505 endomembrane system 3.84306455232871e-07 4640 95 48 0.505263157894737 0.0103448275862069
GO:CC GO:0098552 side of membrane 4.19257785492444e-07 619 40 11 0.275 0.0177705977382876
GO:CC GO:0005774 vacuolar membrane 6.01612689221111e-07 441 83 13 0.156626506024096 0.0294784580498866
GO:CC GO:0030141 secretory granule 7.8728996603727e-07 851 39 12 0.307692307692308 0.0141010575793184
GO:CC GO:0043231 intracellular membrane-bounded organelle 7.91141028447866e-07 11296 86 74 0.86046511627907 0.00655099150141643
GO:CC GO:0005765 lysosomal membrane 9.68906380724148e-07 383 83 12 0.144578313253012 0.031331592689295
GO:CC GO:0098852 lytic vacuole membrane 9.68906380724148e-07 383 83 12 0.144578313253012 0.031331592689295
GO:CC GO:0031984 organelle subcompartment 1.23691224979624e-06 1773 85 25 0.294117647058824 0.0141003948110547
GO:CC GO:0005775 vacuolar lumen 1.38539743499846e-06 174 91 9 0.0989010989010989 0.0517241379310345
GO:CC GO:0030670 phagocytic vesicle membrane 1.47518227458032e-06 76 32 5 0.15625 0.0657894736842105
GO:CC GO:0005770 late endosome 2.66644474732069e-06 275 32 7 0.21875 0.0254545454545455
GO:CC GO:0055038 recycling endosome membrane 2.69452601484813e-06 84 62 6 0.0967741935483871 0.0714285714285714
GO:CC GO:0099503 secretory vesicle 2.93279403774509e-06 1020 92 19 0.206521739130435 0.0186274509803922
GO:CC GO:0005783 endoplasmic reticulum 3.19033464081606e-06 1982 22 12 0.545454545454545 0.00605449041372351
GO:CC GO:0042824 MHC class I peptide loading complex 4.96099578837011e-06 9 38 3 0.0789473684210526 0.333333333333333
GO:CC GO:0031090 organelle membrane 5.01672104265766e-06 3612 85 36 0.423529411764706 0.00996677740863787
GO:CC GO:0009986 cell surface 5.48738270361325e-06 899 18 8 0.444444444444444 0.00889877641824249
GO:CC GO:0008180 COP9 signalosome 5.81613826234642e-06 35 39 4 0.102564102564103 0.114285714285714
GO:CC GO:0030133 transport vesicle 1.16254878563413e-05 414 18 6 0.333333333333333 0.0144927536231884
GO:CC GO:0048471 perinuclear region of cytoplasm 1.56515309991509e-05 735 40 10 0.25 0.0136054421768707
GO:CC GO:0055037 recycling endosome 1.89380277535657e-05 188 62 7 0.112903225806452 0.0372340425531915
GO:CC GO:0031902 late endosome membrane 2.49773373994408e-05 140 32 5 0.15625 0.0357142857142857
GO:CC GO:0043233 organelle lumen 2.66040970882822e-05 5565 63 36 0.571428571428571 0.00646900269541779
GO:CC GO:0031974 membrane-enclosed lumen 2.66040970882822e-05 5565 63 36 0.571428571428571 0.00646900269541779
GO:CC GO:0043227 membrane-bounded organelle 3.1476852383806e-05 12858 63 58 0.920634920634921 0.00451081039041842
GO:CC GO:0032991 protein-containing complex 3.3895443401233e-05 5548 43 27 0.627906976744186 0.00486661860129776
GO:CC GO:0070013 intracellular organelle lumen 3.88510788369441e-05 5402 63 35 0.555555555555556 0.00647908182154758
GO:CC GO:0000139 Golgi membrane 5.01801905321728e-05 771 85 14 0.164705882352941 0.0181582360570687
GO:CC GO:0043229 intracellular organelle 5.57286238630665e-05 12491 89 77 0.865168539325843 0.00616443839564486
GO:CC GO:0031901 early endosome membrane 6.40267521198116e-05 159 17 4 0.235294117647059 0.0251572327044025
GO:CC GO:0005737 cytoplasm 7.24157677616438e-05 11911 46 42 0.91304347826087 0.00352615229619679
GO:CC GO:0005925 focal adhesion 0.000103914149724435 420 38 7 0.184210526315789 0.0166666666666667
GO:CC GO:0030055 cell-substrate junction 0.000114061019663675 427 38 7 0.184210526315789 0.0163934426229508
GO:CC GO:0098791 Golgi apparatus subcompartment 0.000127897013905512 885 27 8 0.296296296296296 0.00903954802259887
GO:CC GO:0034774 secretory granule lumen 0.000133117310770171 320 91 9 0.0989010989010989 0.028125
GO:CC GO:0005794 Golgi apparatus 0.00014035528905295 1623 85 20 0.235294117647059 0.0123228589032656
GO:CC GO:0060205 cytoplasmic vesicle lumen 0.000143094454294674 324 91 9 0.0989010989010989 0.0277777777777778
GO:CC GO:0031983 vesicle lumen 0.000148316538895847 326 91 9 0.0989010989010989 0.0276073619631902
GO:CC GO:0016234 inclusion body 0.000148951016323633 76 15 3 0.2 0.0394736842105263
GO:CC GO:0071944 cell periphery 0.000153518255551787 6169 34 23 0.676470588235294 0.00372831901442697
GO:CC GO:0098797 plasma membrane protein complex 0.000158278521022532 694 18 6 0.333333333333333 0.00864553314121038
GO:CC GO:0005886 plasma membrane 0.000222494257871756 5681 24 17 0.708333333333333 0.00299243091005105
GO:CC GO:0005681 spliceosomal complex 0.000280432879019887 191 41 5 0.121951219512195 0.0261780104712042
GO:CC GO:0005654 nucleoplasm 0.000319385976544213 4102 61 27 0.442622950819672 0.00658215504631887
GO:CC GO:0140513 nuclear protein-containing complex 0.000387982740223798 1249 43 11 0.255813953488372 0.00880704563650921
GO:CC GO:0031981 nuclear lumen 0.00046162948336141 4444 61 28 0.459016393442623 0.0063006300630063
GO:CC GO:0140534 endoplasmic reticulum protein-containing complex 0.000487326256330694 128 69 5 0.072463768115942 0.0390625
GO:CC GO:0005634 nucleus 0.00061771148293759 7592 59 38 0.644067796610169 0.00500526870389884
GO:CC GO:0005776 autophagosome 0.000695280940479723 98 52 4 0.0769230769230769 0.0408163265306122
GO:CC GO:0030665 clathrin-coated vesicle membrane 0.000741046151654746 114 18 3 0.166666666666667 0.0263157894736842
GO:CC GO:0072562 blood microparticle 0.000761946432948394 140 15 3 0.2 0.0214285714285714
GO:CC GO:0070820 tertiary granule 0.000788467064026249 163 33 4 0.121212121212121 0.0245398773006135
GO:CC GO:0000421 autophagosome membrane 0.000845927843672931 41 52 3 0.0576923076923077 0.0731707317073171
GO:CC GO:1990904 ribonucleoprotein complex 0.000845927843672931 688 16 5 0.3125 0.00726744186046512
GO:CC GO:0031904 endosome lumen 0.000915735172568131 35 63 3 0.0476190476190476 0.0857142857142857
GO:CC GO:0043025 neuronal cell body 0.000978964618873868 518 12 4 0.333333333333333 0.00772200772200772
GO:CC GO:0043226 organelle 0.00108922945989243 14008 63 58 0.920634920634921 0.00414049114791548
GO:CC GO:0036477 somatodendritic compartment 0.00120067599964291 871 14 5 0.357142857142857 0.00574052812858783
GO:CC GO:0005769 early endosome 0.00125243708427682 378 17 4 0.235294117647059 0.0105820105820106
GO:CC GO:0044297 cell body 0.00132086741792197 592 56 8 0.142857142857143 0.0135135135135135
GO:CC GO:0005739 mitochondrion 0.00145955780261225 1673 22 8 0.363636363636364 0.00478182904961148
GO:CC GO:0005829 cytosol 0.00169677719713515 5303 46 24 0.521739130434783 0.00452574014708656
GO:CC GO:0030425 dendrite 0.00261616105830876 638 45 7 0.155555555555556 0.0109717868338558
GO:CC GO:0030136 clathrin-coated vesicle 0.00262159266599947 193 40 4 0.1 0.0207253886010363
GO:CC GO:0097447 dendritic tree 0.00262159266599947 640 45 7 0.155555555555556 0.0109375
GO:CC GO:0005622 intracellular anatomical structure 0.00271220500917334 14790 63 59 0.936507936507937 0.00398918187964841
GO:CC GO:0071013 catalytic step 2 spliceosome 0.00289787419980509 85 41 3 0.0731707317073171 0.0352941176470588
GO:CC GO:0098796 membrane protein complex 0.00356546311605857 1322 18 6 0.333333333333333 0.00453857791225416
GO:CC GO:0070161 anchoring junction 0.00416072507994711 836 38 7 0.184210526315789 0.00837320574162679
GO:CC GO:0140535 intracellular protein-containing complex 0.00418616094268005 767 53 8 0.150943396226415 0.0104302477183833
GO:CC GO:0150034 distal axon 0.00460223580450572 308 14 3 0.214285714285714 0.00974025974025974
GO:CC GO:0016020 membrane 0.00473751543625469 9838 24 20 0.833333333333333 0.0020329335230738
GO:CC GO:0031985 Golgi cisterna 0.00584062161243241 115 85 4 0.0470588235294118 0.0347826086956522
GO:CC GO:0030667 secretory granule membrane 0.00590771735641279 303 33 4 0.121212121212121 0.0132013201320132
GO:CC GO:0043005 neuron projection 0.0066465141875584 1380 33 8 0.242424242424242 0.00579710144927536
GO:CC GO:0005814 centriole 0.00949003834960182 142 39 3 0.0769230769230769 0.0211267605633803
GO:CC GO:0016529 sarcoplasmic reticulum 0.0105828756574429 70 82 3 0.0365853658536585 0.0428571428571429
GO:CC GO:0005795 Golgi stack 0.011369352275329 149 40 3 0.075 0.0201342281879195
GO:CC GO:0009897 external side of plasma membrane 0.0117313323921242 408 49 5 0.102040816326531 0.0122549019607843
GO:CC GO:0030424 axon 0.0127549396061835 660 45 6 0.133333333333333 0.00909090909090909
GO:CC GO:0016528 sarcoplasm 0.013614641927835 79 82 3 0.0365853658536585 0.0379746835443038
GO:CC GO:1902494 catalytic complex 0.0161274454255707 1441 53 10 0.188679245283019 0.00693962526023595
GO:CC GO:0030054 cell junction 0.018560077003119 2105 62 14 0.225806451612903 0.00665083135391924
GO:CC GO:0016604 nuclear body 0.0190028316670642 816 53 7 0.132075471698113 0.00857843137254902
GO:CC GO:0005887 integral component of plasma membrane 0.0190028316670642 1645 21 6 0.285714285714286 0.00364741641337386
GO:CC GO:0005788 endoplasmic reticulum lumen 0.0199069639770622 307 76 5 0.0657894736842105 0.0162866449511401
GO:CC GO:0031226 intrinsic component of plasma membrane 0.022804594222471 1726 21 6 0.285714285714286 0.00347624565469293
GO:CC GO:0005730 nucleolus 0.0266722857392954 955 61 8 0.131147540983607 0.00837696335078534
GO:CC GO:0120025 plasma membrane bounded cell projection 0.0277882313378103 2229 33 9 0.272727272727273 0.00403768506056528
GO:CC GO:0045177 apical part of cell 0.0315805533955493 431 87 6 0.0689655172413793 0.0139211136890951
GO:CC GO:0016607 nuclear speck 0.0326299456933042 412 44 4 0.0909090909090909 0.00970873786407767
GO:CC GO:0042995 cell projection 0.0333815803615989 2330 33 9 0.272727272727273 0.00386266094420601
GO:CC GO:0005793 endoplasmic reticulum-Golgi intermediate compartment 0.0337477530289148 131 76 3 0.0394736842105263 0.0229007633587786
GO:CC GO:0015630 microtubule cytoskeleton 0.0342269041043278 1307 39 7 0.179487179487179 0.0053557765876052
GO:CC GO:0016324 apical plasma membrane 0.0399079197348021 361 81 5 0.0617283950617284 0.0138504155124654
GO:MF GO:0044183 protein folding chaperone 1.68929289831691e-12 35 39 8 0.205128205128205 0.228571428571429
GO:MF GO:0051082 unfolded protein binding 2.93501676620562e-10 112 39 9 0.230769230769231 0.0803571428571429
GO:MF GO:0023026 MHC class II protein complex binding 4.12703151031514e-10 17 18 5 0.277777777777778 0.294117647058824
GO:MF GO:0031625 ubiquitin protein ligase binding 1.65576896498186e-09 296 39 11 0.282051282051282 0.0371621621621622
GO:MF GO:0055131 C3HC4-type RING finger domain binding 1.76351801070799e-09 6 22 4 0.181818181818182 0.666666666666667
GO:MF GO:0023023 MHC protein complex binding 1.76351801070799e-09 25 18 5 0.277777777777778 0.2
GO:MF GO:0044389 ubiquitin-like protein ligase binding 1.78579188362021e-09 314 39 11 0.282051282051282 0.035031847133758
GO:MF GO:0042605 peptide antigen binding 3.53731211605589e-09 30 18 5 0.277777777777778 0.166666666666667
GO:MF GO:0031072 heat shock protein binding 2.96251389317785e-07 127 22 6 0.272727272727273 0.047244094488189
GO:MF GO:0042277 peptide binding 3.20762380234599e-07 314 63 11 0.174603174603175 0.035031847133758
GO:MF GO:0046977 TAP binding 2.1215792854983e-06 9 17 3 0.176470588235294 0.333333333333333
GO:MF GO:0033218 amide binding 2.40458230539037e-06 389 63 11 0.174603174603175 0.0282776349614396
GO:MF GO:0042608 T cell receptor binding 4.22538534902159e-06 11 18 3 0.166666666666667 0.272727272727273
GO:MF GO:0051787 misfolded protein binding 1.01899908395862e-05 28 39 4 0.102564102564103 0.142857142857143
GO:MF GO:0003823 antigen binding 1.10430762501216e-05 163 18 5 0.277777777777778 0.0306748466257669
GO:MF GO:0019899 enzyme binding 1.10770115819544e-05 2074 53 20 0.377358490566038 0.00964320154291225
GO:MF GO:0003723 RNA binding 1.68740437567705e-05 1943 16 10 0.625 0.00514668039114771
GO:MF GO:0019904 protein domain specific binding 2.00851000837305e-05 710 37 10 0.27027027027027 0.0140845070422535
GO:MF GO:0016887 ATPase activity 2.96116582144949e-05 488 15 6 0.4 0.0122950819672131
GO:MF GO:0042826 histone deacetylase binding 3.87663826239237e-05 116 15 4 0.266666666666667 0.0344827586206897
GO:MF GO:0097718 disordered domain specific binding 4.99825239550222e-05 34 15 3 0.2 0.0882352941176471
GO:MF GO:0051087 chaperone binding 0.000105246183275328 103 22 4 0.181818181818182 0.0388349514563107
GO:MF GO:0005102 signaling receptor binding 0.000130263468896136 1672 22 10 0.454545454545455 0.00598086124401914
GO:MF GO:0017111 nucleoside-triphosphatase activity 0.000239355388682374 872 19 7 0.368421052631579 0.00802752293577982
GO:MF GO:0045296 cadherin binding 0.000263146917256097 333 19 5 0.263157894736842 0.015015015015015
GO:MF GO:0016817 hydrolase activity, acting on acid anhydrides 0.000306908857360573 930 19 7 0.368421052631579 0.00752688172043011
GO:MF GO:0016462 pyrophosphatase activity 0.000306908857360573 928 19 7 0.368421052631579 0.00754310344827586
GO:MF GO:0016818 hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides 0.000306908857360573 930 19 7 0.368421052631579 0.00752688172043011
GO:MF GO:0005524 ATP binding 0.000458528919986818 1501 39 12 0.307692307692308 0.00799467021985343
GO:MF GO:0032559 adenyl ribonucleotide binding 0.000672396028494631 1565 39 12 0.307692307692308 0.00766773162939297
GO:MF GO:0035639 purine ribonucleoside triphosphate binding 0.000689780318456728 1847 39 13 0.333333333333333 0.00703844071467244
GO:MF GO:0030554 adenyl nucleotide binding 0.000689780318456728 1578 39 12 0.307692307692308 0.00760456273764259
GO:MF GO:0050750 low-density lipoprotein particle receptor binding 0.000723005447325029 23 63 3 0.0476190476190476 0.130434782608696
GO:MF GO:0032555 purine ribonucleotide binding 0.000966187623597183 1918 39 13 0.333333333333333 0.00677789363920751
GO:MF GO:0017076 purine nucleotide binding 0.00100679031024444 1933 39 13 0.333333333333333 0.00672529746508019
GO:MF GO:0032553 ribonucleotide binding 0.00100679031024444 1935 39 13 0.333333333333333 0.00671834625322997
GO:MF GO:0070325 lipoprotein particle receptor binding 0.00119557178048926 28 63 3 0.0476190476190476 0.107142857142857
GO:MF GO:0044877 protein-containing complex binding 0.00119649901868643 1287 18 7 0.388888888888889 0.00543900543900544
GO:MF GO:0097367 carbohydrate derivative binding 0.00121832744514472 2285 39 14 0.358974358974359 0.00612691466083151
GO:MF GO:0061629 RNA polymerase II-specific DNA-binding transcription factor binding 0.00134930592770104 281 53 6 0.113207547169811 0.0213523131672598
GO:MF GO:0050839 cell adhesion molecule binding 0.00164291586076929 546 19 5 0.263157894736842 0.00915750915750916
GO:MF GO:1901265 nucleoside phosphate binding 0.00261163096890806 2172 39 13 0.333333333333333 0.00598526703499079
GO:MF GO:0001618 virus receptor activity 0.00261163096890806 76 32 3 0.09375 0.0394736842105263
GO:MF GO:0000166 nucleotide binding 0.00261163096890806 2171 39 13 0.333333333333333 0.00598802395209581
GO:MF GO:0140272 exogenous protein binding 0.00262431256569357 77 32 3 0.09375 0.038961038961039
GO:MF GO:0036094 small molecule binding 0.00277915852726202 2506 39 14 0.358974358974359 0.00558659217877095
GO:MF GO:0001664 G protein-coupled receptor binding 0.00282551683573845 292 22 4 0.181818181818182 0.0136986301369863
GO:MF GO:0003676 nucleic acid binding 0.00502448188482499 4276 59 25 0.423728813559322 0.0058465855940131
GO:MF GO:1901363 heterocyclic compound binding 0.00521639592353179 6228 59 32 0.542372881355932 0.00513808606294155
GO:MF GO:0140297 DNA-binding transcription factor binding 0.00546562307748285 391 53 6 0.113207547169811 0.0153452685421995
GO:MF GO:0043168 anion binding 0.00566516882596831 2418 39 13 0.333333333333333 0.00537634408602151
GO:MF GO:0097159 organic cyclic compound binding 0.00630486767871953 6309 59 32 0.542372881355932 0.00507211919480108
GO:MF GO:0005515 protein binding 0.0102240991831957 14767 54 51 0.944444444444444 0.00345364664454527
GO:MF GO:0001540 amyloid-beta binding 0.0145217764615127 83 63 3 0.0476190476190476 0.036144578313253
GO:MF GO:0008134 transcription factor binding 0.014804793382882 676 53 7 0.132075471698113 0.0103550295857988
GO:MF GO:0030234 enzyme regulator activity 0.0162991016640536 1248 23 6 0.260869565217391 0.00480769230769231
GO:MF GO:0016787 hydrolase activity 0.0162991016640536 2615 71 19 0.267605633802817 0.00726577437858509
GO:MF GO:0016667 oxidoreductase activity, acting on a sulfur group of donors 0.0167478724665888 60 95 3 0.0315789473684211 0.05
GO:MF GO:0042803 protein homodimerization activity 0.020323053177719 676 10 3 0.3 0.00443786982248521
GO:MF GO:0035257 nuclear hormone receptor binding 0.0322555888700097 148 53 3 0.0566037735849057 0.0202702702702703
GO:MF GO:0004553 hydrolase activity, hydrolyzing O-glycosyl compounds 0.0371183714884978 99 85 3 0.0352941176470588 0.0303030303030303
GO:MF GO:0098772 molecular function regulator 0.0419171293887429 2363 26 8 0.307692307692308 0.00338552687261955
GO:MF GO:0051427 hormone receptor binding 0.0477915129386983 182 53 3 0.0566037735849057 0.0164835164835165
HP HP:0001922 Vacuolated lymphocytes 0.0333993516037574 9 91 4 0.043956043956044 0.444444444444444
HP HP:0007267 Chronic axonal neuropathy 0.0421960588176056 7 69 3 0.0434782608695652 0.428571428571429
HP HP:0003765 Psoriasiform dermatitis 0.0421960588176056 25 42 4 0.0952380952380952 0.16
HP HP:0001097 Keratoconjunctivitis sicca 0.0421960588176056 39 10 3 0.3 0.0769230769230769
HP HP:0001096 Keratoconjunctivitis 0.0421960588176056 43 10 3 0.3 0.0697674418604651
HPA HPA:0080123 caudate; glial cells[High] 0.000236596542937156 628 48 13 0.270833333333333 0.0207006369426752
HPA HPA:0390053 prostate; glandular cells[High] 0.000236596542937156 1284 50 19 0.38 0.014797507788162
HPA HPA:0160053 endometrium 1; glandular cells[High] 0.000236596542937156 1413 50 20 0.4 0.0141542816702052
HPA HPA:0310442 lymph node; non-germinal center cells[≥Medium] 0.000236596542937156 3875 51 35 0.686274509803922 0.00903225806451613
HPA HPA:0530000 spleen 0.000731104128707473 5756 53 43 0.811320754716981 0.00747046560111188
HPA HPA:0610833 urinary bladder; urothelial cells[High] 0.000731104128707473 1969 53 23 0.433962264150943 0.0116810563737938
HPA HPA:0110223 cervix, uterine; squamous epithelial cells[High] 0.000731104128707473 986 44 14 0.318181818181818 0.0141987829614604
HPA HPA:0460643 skin 1; Langerhans[High] 0.000731104128707473 734 44 12 0.272727272727273 0.0163487738419619
HPA HPA:0100123 cerebral cortex; glial cells[High] 0.000731104128707473 683 45 12 0.266666666666667 0.0175695461200586
HPA HPA:0310443 lymph node; non-germinal center cells[High] 0.000731104128707473 1169 50 17 0.34 0.0145423438836612
HPA HPA:0600442 tonsil; non-germinal center cells[≥Medium] 0.000731104128707473 4079 51 34 0.666666666666667 0.00833537631772493
HPA HPA:0600433 tonsil; germinal center cells[High] 0.000731104128707473 1179 61 19 0.311475409836066 0.0161153519932146
HPA HPA:0291162 liver; cholangiocytes[≥Medium] 0.000731104128707473 1910 51 22 0.431372549019608 0.0115183246073298
HPA HPA:0600443 tonsil; non-germinal center cells[High] 0.000731104128707473 1271 10 7 0.7 0.00550747442958301
HPA HPA:0380513 placenta; decidual cells[High] 0.000731104128707473 1144 77 22 0.285714285714286 0.0192307692307692
HPA HPA:0211093 fallopian tube; non-ciliated cells[High] 0.000731104128707473 74 24 4 0.166666666666667 0.0540540540540541
HPA HPA:0590053 thyroid gland; glandular cells[High] 0.000966933082862576 1804 63 24 0.380952380952381 0.0133037694013304
HPA HPA:0530711 spleen; cells in red pulp[≥Low] 0.00103720593640463 5195 53 40 0.754716981132076 0.00769971126082772
HPA HPA:0170052 endometrium 2; glandular cells[≥Medium] 0.00103720593640463 4758 53 38 0.716981132075472 0.00798654897015553
HPA HPA:0160052 endometrium 1; glandular cells[≥Medium] 0.00119930618008692 5014 53 39 0.735849056603774 0.00777822098125249
HPA HPA:0460642 skin 1; Langerhans[≥Medium] 0.00141197278647173 3123 53 29 0.547169811320755 0.00928594300352226
HPA HPA:0180053 epididymis; glandular cells[High] 0.00141197278647173 1779 74 26 0.351351351351351 0.0146149522203485
HPA HPA:0080121 caudate; glial cells[≥Low] 0.00141197278647173 4464 51 35 0.686274509803922 0.00784050179211469
HPA HPA:0170252 endometrium 2; cells in endometrial stroma[≥Medium] 0.00159131589770911 1722 77 26 0.337662337662338 0.0150987224157956
HPA HPA:0110053 cervix, uterine; glandular cells[High] 0.00173426185495774 1135 44 14 0.318181818181818 0.0123348017621145
HPA HPA:0060103 bronchus; respiratory epithelial cells[High] 0.00192293737995587 1890 53 21 0.39622641509434 0.0111111111111111
HPA HPA:0090193 cerebellum; cells in molecular layer[High] 0.00192293737995587 874 50 13 0.26 0.0148741418764302
HPA HPA:0160251 endometrium 1; cells in endometrial stroma[≥Low] 0.00209546930229204 3962 53 33 0.622641509433962 0.00832912670368501
HPA HPA:0170251 endometrium 2; cells in endometrial stroma[≥Low] 0.0021062151375304 3410 53 30 0.566037735849057 0.00879765395894428
HPA HPA:0530721 spleen; cells in white pulp[≥Low] 0.00215229695351229 4249 80 48 0.6 0.0112967757119322
HPA HPA:0600432 tonsil; germinal center cells[≥Medium] 0.00218764237447518 3988 53 33 0.622641509433962 0.00827482447342026
HPA HPA:0460663 skin 1; keratinocytes[High] 0.00220280012408582 848 5 4 0.8 0.00471698113207547
HPA HPA:0470683 skin 2; epidermal cells[High] 0.00220280012408582 1346 44 15 0.340909090909091 0.0111441307578009
HPA HPA:0030072 appendix; lymphoid tissue[≥Medium] 0.00232349865676427 3131 55 29 0.527272727272727 0.00926221654423507
HPA HPA:0210853 fallopian tube; ciliated cells (cell body)[High] 0.00250458387383054 104 58 5 0.0862068965517241 0.0480769230769231
HPA HPA:0500111 soft tissue 1; chondrocytes[≥Low] 0.00250458387383054 2129 53 22 0.415094339622642 0.0103334899013621
HPA HPA:0570763 testis; pachytene spermatocytes[High] 0.00250458387383054 822 63 14 0.222222222222222 0.0170316301703163
HPA HPA:0600222 tonsil; squamous epithelial cells[≥Medium] 0.00250458387383054 4851 46 33 0.717391304347826 0.00680272108843537
HPA HPA:0460673 skin 1; melanocytes[High] 0.00251188592422539 848 48 12 0.25 0.0141509433962264
HPA HPA:0600441 tonsil; non-germinal center cells[≥Low] 0.00251188592422539 5966 53 42 0.792452830188679 0.00703989272544418
HPA HPA:0160252 endometrium 1; cells in endometrial stroma[≥Medium] 0.00251188592422539 2142 53 22 0.415094339622642 0.0102707749766573
HPA HPA:0100122 cerebral cortex; glial cells[≥Medium] 0.00251188592422539 2588 45 22 0.488888888888889 0.00850077279752705
HPA HPA:0460672 skin 1; melanocytes[≥Medium] 0.00253957989011106 3700 53 31 0.584905660377358 0.00837837837837838
HPA HPA:0080133 caudate; neuronal cells[High] 0.00253957989011106 1059 45 13 0.288888888888889 0.012275731822474
HPA HPA:0340462 ovary; ovarian stroma cells[≥Medium] 0.00258638788911425 2002 53 21 0.39622641509434 0.0104895104895105
HPA HPA:0390052 prostate; glandular cells[≥Medium] 0.00264958385640155 4699 75 48 0.64 0.0102149393487976
HPA HPA:0220053 gallbladder; glandular cells[High] 0.0028963138296911 2772 77 34 0.441558441558442 0.0122655122655123
HPA HPA:0040082 bone marrow; hematopoietic cells[≥Medium] 0.0028963138296911 4126 45 29 0.644444444444444 0.00702859912748425
HPA HPA:0110052 cervix, uterine; glandular cells[≥Medium] 0.00297363229581802 3938 53 32 0.60377358490566 0.00812595226003047
HPA HPA:0291163 liver; cholangiocytes[High] 0.00300364842632012 294 50 7 0.14 0.0238095238095238
HPA HPA:0050092 breast; myoepithelial cells[≥Medium] 0.00300364842632012 3700 45 27 0.6 0.0072972972972973
HPA HPA:0610832 urinary bladder; urothelial cells[≥Medium] 0.00300364842632012 5819 53 41 0.773584905660377 0.00704588417253824
HPA HPA:0211091 fallopian tube; non-ciliated cells[≥Low] 0.00300364842632012 456 24 6 0.25 0.0131578947368421
HPA HPA:0500702 soft tissue 1; peripheral nerve[≥Medium] 0.00392267445419493 1311 70 19 0.271428571428571 0.0144927536231884
HPA HPA:0530722 spleen; cells in white pulp[≥Medium] 0.00418709184701263 2645 55 25 0.454545454545455 0.00945179584120983
HPA HPA:0050053 breast; glandular cells[High] 0.00418709184701263 1299 45 14 0.311111111111111 0.0107775211701309
HPA HPA:0310441 lymph node; non-germinal center cells[≥Low] 0.00421447959590765 5915 56 43 0.767857142857143 0.00726965342349958
HPA HPA:0210852 fallopian tube; ciliated cells (cell body)[≥Medium] 0.00451152790156514 372 70 9 0.128571428571429 0.0241935483870968
HPA HPA:0211092 fallopian tube; non-ciliated cells[≥Medium] 0.00461775268861532 328 24 5 0.208333333333333 0.0152439024390244
HPA HPA:0301172 lung; alveolar cells[≥Medium] 0.0048536436163202 2863 44 22 0.5 0.00768424729304925
HPA HPA:0060853 bronchus; ciliated cells (cell body)[High] 0.0048536436163202 181 89 7 0.0786516853932584 0.0386740331491713
HPA HPA:0310433 lymph node; germinal center cells[High] 0.0048536436163202 908 10 5 0.5 0.00550660792951542
HPA HPA:0100201 cerebral cortex; endothelial cells[≥Low] 0.0048536436163202 4556 81 49 0.604938271604938 0.0107550482879719
HPA HPA:0060852 bronchus; ciliated cells (cell body)[≥Medium] 0.0048536436163202 548 70 11 0.157142857142857 0.0200729927007299
HPA HPA:0600431 tonsil; germinal center cells[≥Low] 0.00548970643451106 5845 95 67 0.705263157894737 0.0114627887082977
HPA HPA:0250121 hippocampus; glial cells[≥Low] 0.00585028791217641 4033 52 31 0.596153846153846 0.00768658566823704
HPA HPA:0310431 lymph node; germinal center cells[≥Low] 0.00585028791217641 4935 53 36 0.679245283018868 0.00729483282674772
HPA HPA:0310432 lymph node; germinal center cells[≥Medium] 0.00589395135343737 3209 53 27 0.509433962264151 0.0084138360860081
HPA HPA:0570803 testis; sertoli cells[High] 0.00589395135343737 536 97 13 0.134020618556701 0.0242537313432836
HPA HPA:0570801 testis; sertoli cells[≥Low] 0.00590481945207098 2256 76 28 0.368421052631579 0.0124113475177305
HPA HPA:0210053 fallopian tube; glandular cells[High] 0.00590481945207098 1728 53 18 0.339622641509434 0.0104166666666667
HPA HPA:0420052 salivary gland; glandular cells[≥Medium] 0.00590481945207098 4742 53 35 0.660377358490566 0.00738085196119781
HPA HPA:0090183 cerebellum; cells in granular layer[High] 0.00592469931372664 709 4 3 0.75 0.00423131170662906
HPA HPA:0250123 hippocampus; glial cells[High] 0.00592469931372664 508 45 8 0.177777777777778 0.015748031496063
HPA HPA:0300413 lung; macrophages[High] 0.00699723976825471 1224 74 18 0.243243243243243 0.0147058823529412
HPA HPA:0010000 adipose tissue 0.00701698335070622 3848 44 26 0.590909090909091 0.00675675675675676
HPA HPA:0010011 adipose tissue; adipocytes[≥Low] 0.00701698335070622 3848 44 26 0.590909090909091 0.00675675675675676
HPA HPA:0490693 smooth muscle; smooth muscle cells[High] 0.0071900553922787 589 50 9 0.18 0.0152801358234295
HPA HPA:0110051 cervix, uterine; glandular cells[≥Low] 0.00722358683068264 5579 44 33 0.75 0.00591503853737229
HPA HPA:0500112 soft tissue 1; chondrocytes[≥Medium] 0.00733738473668612 1395 41 13 0.317073170731707 0.00931899641577061
HPA HPA:0130202 colon; endothelial cells[≥Medium] 0.00738948455919492 3655 53 29 0.547169811320755 0.0079343365253078
HPA HPA:0040081 bone marrow; hematopoietic cells[≥Low] 0.00738948455919492 6349 53 42 0.792452830188679 0.00661521499448732
HPA HPA:0040000 bone marrow 0.00738948455919492 6349 53 42 0.792452830188679 0.00661521499448732
HPA HPA:0460641 skin 1; Langerhans[≥Low] 0.00759118659292627 4634 53 34 0.641509433962264 0.0073370738023306
HPA HPA:0460653 skin 1; fibroblasts[High] 0.00780601831928761 816 4 3 0.75 0.00367647058823529
HPA HPA:0310000 lymph node 0.00794280994494066 6374 53 42 0.792452830188679 0.00658926890492626
HPA HPA:0210851 fallopian tube; ciliated cells (cell body)[≥Low] 0.00844156029109835 611 70 11 0.157142857142857 0.0180032733224223
HPA HPA:0340461 ovary; ovarian stroma cells[≥Low] 0.00867888003520627 3894 53 30 0.566037735849057 0.00770416024653313
HPA HPA:0160051 endometrium 1; glandular cells[≥Low] 0.00923008584098707 6663 46 38 0.826086956521739 0.00570313672519886
HPA HPA:0320103 nasopharynx; respiratory epithelial cells[High] 0.0100078734822445 1844 53 18 0.339622641509434 0.00976138828633406
HPA HPA:0060842 bronchus; basal cells[≥Medium] 0.0104871244737347 259 24 4 0.166666666666667 0.0154440154440154
HPA HPA:0270352 kidney; cells in glomeruli[≥Medium] 0.0110373439666138 2914 78 33 0.423076923076923 0.0113246396705559
HPA HPA:0470682 skin 2; epidermal cells[≥Medium] 0.0115764524747566 4735 44 29 0.659090909090909 0.00612460401267159
HPA HPA:0330222 oral mucosa; squamous epithelial cells[≥Medium] 0.0115764524747566 4254 44 27 0.613636363636364 0.00634696755994358
HPA HPA:0020053 adrenal gland; glandular cells[High] 0.0115764524747566 2199 53 20 0.377358490566038 0.00909504320145521
HPA HPA:0030073 appendix; lymphoid tissue[High] 0.0123689459119893 803 74 13 0.175675675675676 0.0161892901618929
HPA HPA:0430053 seminal vesicle; glandular cells[High] 0.0123689459119893 1410 75 19 0.253333333333333 0.0134751773049645
HPA HPA:0500113 soft tissue 1; chondrocytes[High] 0.0123689459119893 296 70 7 0.1 0.0236486486486486
HPA HPA:0530713 spleen; cells in red pulp[High] 0.0127642992757207 778 68 12 0.176470588235294 0.0154241645244216
HPA HPA:0380512 placenta; decidual cells[≥Medium] 0.0134953531397132 3463 53 27 0.509433962264151 0.00779670805659833
HPA HPA:0510701 soft tissue 2; peripheral nerve[≥Low] 0.0134953531397132 3100 53 25 0.471698113207547 0.00806451612903226
HPA HPA:0060851 bronchus; ciliated cells (cell body)[≥Low] 0.0134953531397132 779 60 11 0.183333333333333 0.0141206675224647
HPA HPA:0570762 testis; pachytene spermatocytes[≥Medium] 0.0135165538621247 1658 75 21 0.28 0.0126658624849216
HPA HPA:0130241 colon; peripheral nerve/ganglion[≥Low] 0.0135165538621247 5037 53 35 0.660377358490566 0.00694858050426841
HPA HPA:0590052 thyroid gland; glandular cells[≥Medium] 0.0135165538621247 5454 53 37 0.69811320754717 0.00678401173450678
HPA HPA:0130201 colon; endothelial cells[≥Low] 0.0135165538621247 5671 53 38 0.716981132075472 0.006700758243696
HPA HPA:0620223 vagina; squamous epithelial cells[High] 0.0135165538621247 1091 44 11 0.25 0.0100824931255729
HPA HPA:0500000 soft tissue 1 0.0135165538621247 5242 53 36 0.679245283018868 0.00686760778328882
HPA HPA:0301171 lung; alveolar cells[≥Low] 0.0135165538621247 5028 53 35 0.660377358490566 0.00696101829753381
HPA HPA:0291161 liver; cholangiocytes[≥Low] 0.0135165538621247 3867 80 41 0.5125 0.0106025342642876
HPA HPA:0600223 tonsil; squamous epithelial cells[High] 0.0140953547624972 1442 44 13 0.295454545454545 0.00901525658807212
HPA HPA:0090942 cerebellum; Purkinje cells - cytoplasm/membrane[≥Medium] 0.0140953547624972 368 75 8 0.106666666666667 0.0217391304347826
HPA HPA:0510702 soft tissue 2; peripheral nerve[≥Medium] 0.0141725651064374 1477 48 14 0.291666666666667 0.00947867298578199
HPA HPA:0330223 oral mucosa; squamous epithelial cells[High] 0.0141725651064374 1112 4 3 0.75 0.00269784172661871
HPA HPA:0380523 placenta; trophoblastic cells[High] 0.0144465234306451 1998 84 26 0.30952380952381 0.013013013013013
HPA HPA:0510000 soft tissue 2 0.0150347695813846 5082 53 35 0.660377358490566 0.0068870523415978
HPA HPA:0500701 soft tissue 1; peripheral nerve[≥Low] 0.0150347695813846 2740 51 22 0.431372549019608 0.00802919708029197
HPA HPA:0100133 cerebral cortex; neuronal cells[High] 0.0151571644278867 1785 45 15 0.333333333333333 0.00840336134453781
HPA HPA:0190223 esophagus; squamous epithelial cells[High] 0.0151571644278867 1596 69 19 0.27536231884058 0.0119047619047619
HPA HPA:0270353 kidney; cells in glomeruli[High] 0.0156805421396053 742 84 13 0.154761904761905 0.0175202156334232
HPA HPA:0100121 cerebral cortex; glial cells[≥Low] 0.0158407853020506 4804 52 33 0.634615384615385 0.00686927560366361
HPA HPA:0160000 endometrium 1 0.0160613962757152 6894 46 38 0.826086956521739 0.0055120394545982
HPA HPA:0270351 kidney; cells in glomeruli[≥Low] 0.0179372102902078 5033 45 30 0.666666666666667 0.00596065964633419
HPA HPA:0091002 cerebellum; molecular layer cells - cytoplasm/membrane[≥Medium] 0.0179372102902078 309 75 7 0.0933333333333333 0.0226537216828479
HPA HPA:0080122 caudate; glial cells[≥Medium] 0.0179372102902078 2230 48 18 0.375 0.00807174887892377
HPA HPA:0040083 bone marrow; hematopoietic cells[High] 0.018795312296015 1376 48 13 0.270833333333333 0.00944767441860465
HPA HPA:0300000 lung 0.0192225639052478 7163 53 44 0.830188679245283 0.00614267764902974
HPA HPA:0110222 cervix, uterine; squamous epithelial cells[≥Medium] 0.0199346701829516 3617 41 22 0.536585365853659 0.00608238871993365
HPA HPA:0300411 lung; macrophages[≥Low] 0.0203986918447575 6645 52 41 0.788461538461538 0.00617005267118134
HPA HPA:0090952 cerebellum; Purkinje cells - dendrites[≥Medium] 0.0203986918447575 210 61 5 0.0819672131147541 0.0238095238095238
HPA HPA:0250122 hippocampus; glial cells[≥Medium] 0.0210871162368989 1926 77 23 0.298701298701299 0.0119418483904465
HPA HPA:0060841 bronchus; basal cells[≥Low] 0.0215106238806885 352 24 4 0.166666666666667 0.0113636363636364
HPA HPA:0420051 salivary gland; glandular cells[≥Low] 0.0221843279344245 6744 53 42 0.792452830188679 0.00622775800711744
HPA HPA:0420000 salivary gland 0.0221843279344245 6744 53 42 0.792452830188679 0.00622775800711744
HPA HPA:0600221 tonsil; squamous epithelial cells[≥Low] 0.0222293547196676 6518 53 41 0.773584905660377 0.00629027308990488
HPA HPA:0210000 fallopian tube 0.0228414019314327 7302 46 39 0.847826086956522 0.00534100246507806
HPA HPA:0510651 soft tissue 2; fibroblasts[≥Low] 0.0230370144805987 4037 53 29 0.547169811320755 0.00718355214268021
HPA HPA:0250132 hippocampus; neuronal cells[≥Medium] 0.0230370144805987 4126 52 29 0.557692307692308 0.00702859912748425
HPA HPA:0050012 breast; adipocytes[≥Medium] 0.023211213491738 1445 7 4 0.571428571428571 0.0027681660899654
HPA HPA:0170053 endometrium 2; glandular cells[High] 0.0232916498698475 1282 77 17 0.220779220779221 0.0132605304212168
HPA HPA:0320841 nasopharynx; basal cells[≥Low] 0.0238074837103639 370 24 4 0.166666666666667 0.0108108108108108
HPA HPA:0030071 appendix; lymphoid tissue[≥Low] 0.0238074837103639 4976 61 38 0.622950819672131 0.00763665594855305
HPA HPA:0460652 skin 1; fibroblasts[≥Medium] 0.0239549858746407 3304 77 34 0.441558441558442 0.0102905569007264
HPA HPA:0050052 breast; glandular cells[≥Medium] 0.0239549858746407 4971 78 47 0.602564102564103 0.00945483806075236
HPA HPA:0091003 cerebellum; molecular layer cells - cytoplasm/membrane[High] 0.023977128361344 182 75 5 0.0666666666666667 0.0274725274725275
HPA HPA:0301173 lung; alveolar cells[High] 0.0239820196121108 778 50 9 0.18 0.0115681233933162
HPA HPA:0130242 colon; peripheral nerve/ganglion[≥Medium] 0.0239820196121108 3406 75 34 0.453333333333333 0.00998238402818555
HPA HPA:0170051 endometrium 2; glandular cells[≥Low] 0.024407648618389 6568 53 41 0.773584905660377 0.00624238733252132
HPA HPA:0010012 adipose tissue; adipocytes[≥Medium] 0.0246955657754668 2168 44 16 0.363636363636364 0.00738007380073801
HPA HPA:0360053 parathyroid gland; glandular cells[High] 0.0249342042208491 1486 4 3 0.75 0.00201884253028264
HPA HPA:0550053 stomach 2; glandular cells[High] 0.0249342042208491 2350 5 4 0.8 0.00170212765957447
HPA HPA:0090951 cerebellum; Purkinje cells - dendrites[≥Low] 0.0252656671701432 230 61 5 0.0819672131147541 0.0217391304347826
HPA HPA:0351181 pancreas; pancreatic endocrine cells[≥Low] 0.0252656671701432 5497 53 36 0.679245283018868 0.0065490267418592
HPA HPA:0091001 cerebellum; molecular layer cells - cytoplasm/membrane[≥Low] 0.0253201440949674 343 75 7 0.0933333333333333 0.0204081632653061
HPA HPA:0570802 testis; sertoli cells[≥Medium] 0.0254909558966714 1662 76 20 0.263157894736842 0.0120336943441637
HPA HPA:0050091 breast; myoepithelial cells[≥Low] 0.0260552455663977 5551 46 32 0.695652173913043 0.00576472707620249
HPA HPA:0380522 placenta; trophoblastic cells[≥Medium] 0.0262385092783245 5074 46 30 0.652173913043478 0.00591249507292077
HPA HPA:0100202 cerebral cortex; endothelial cells[≥Medium] 0.0266288101090592 2425 5 4 0.8 0.00164948453608247
HPA HPA:0090943 cerebellum; Purkinje cells - cytoplasm/membrane[High] 0.0266288101090592 191 75 5 0.0666666666666667 0.0261780104712042
HPA HPA:0530712 spleen; cells in red pulp[≥Medium] 0.0267621806322551 3049 55 24 0.436363636363636 0.00787143325680551
HPA HPA:0380511 placenta; decidual cells[≥Low] 0.026907282248489 4716 51 31 0.607843137254902 0.00657336726039016
HPA HPA:0470681 skin 2; epidermal cells[≥Low] 0.0284045405343403 6608 46 36 0.782608695652174 0.00544794188861985
HPA HPA:0610831 urinary bladder; urothelial cells[≥Low] 0.0284045405343403 7141 46 38 0.826086956521739 0.00532138355972553
HPA HPA:0470000 skin 2 0.0284045405343403 6608 46 36 0.782608695652174 0.00544794188861985
HPA HPA:0610000 urinary bladder 0.0284045405343403 7141 46 38 0.826086956521739 0.00532138355972553
HPA HPA:0351183 pancreas; pancreatic endocrine cells[High] 0.0288691095348646 758 63 10 0.158730158730159 0.0131926121372032
HPA HPA:0570813 testis; spermatogonia cells[High] 0.028954330956434 1281 44 11 0.25 0.00858704137392662
HPA HPA:0600000 tonsil 0.0291268921111308 7618 58 49 0.844827586206897 0.00643213441848254
HPA HPA:0550052 stomach 2; glandular cells[≥Medium] 0.029139557138124 6134 52 38 0.730769230769231 0.00619497880665145
HPA HPA:0050051 breast; glandular cells[≥Low] 0.029139557138124 6659 53 41 0.773584905660377 0.00615708064273915
HPA HPA:0090941 cerebellum; Purkinje cells - cytoplasm/membrane[≥Low] 0.029139557138124 448 75 8 0.106666666666667 0.0178571428571429
HPA HPA:0460671 skin 1; melanocytes[≥Low] 0.0306307996670934 5378 53 35 0.660377358490566 0.00650799553737449
HPA HPA:0190222 esophagus; squamous epithelial cells[≥Medium] 0.0306307996670934 4937 44 28 0.636363636363636 0.00567146040105327
HPA HPA:0320842 nasopharynx; basal cells[≥Medium] 0.0306307996670934 288 19 3 0.157894736842105 0.0104166666666667
HPA HPA:0241103 heart muscle; cardiomyocytes[High] 0.0309501328382237 1113 51 11 0.215686274509804 0.00988319856244385
HPA HPA:0220052 gallbladder; glandular cells[≥Medium] 0.0310146850878289 6461 53 40 0.754716981132076 0.00619099210648506
HPA HPA:0110000 cervix, uterine 0.0320181159838598 6778 44 35 0.795454545454545 0.005163765122455
HPA HPA:0050093 breast; myoepithelial cells[High] 0.0320181159838598 798 80 12 0.15 0.0150375939849624
HPA HPA:0500651 soft tissue 1; fibroblasts[≥Low] 0.0320181159838598 4156 80 41 0.5125 0.00986525505293552
HPA HPA:0090902 cerebellum; Bergmann glia - cytoplasm/membrane[≥Medium] 0.0335983824474585 89 63 3 0.0476190476190476 0.0337078651685393
HPA HPA:0340453 ovary; follicle cells[High] 0.0342332559031932 579 85 10 0.117647058823529 0.0172711571675302
HPA HPA:0210052 fallopian tube; glandular cells[≥Medium] 0.0353871100783489 5023 53 33 0.622641509433962 0.00656977901652399
HPA HPA:0480053 small intestine; glandular cells[High] 0.035538416029196 2723 5 4 0.8 0.00146896804994491
HPA HPA:0460662 skin 1; keratinocytes[≥Medium] 0.0357004087128376 3893 41 22 0.536585365853659 0.00565116876444901
HPA HPA:0020052 adrenal gland; glandular cells[≥Medium] 0.0358946093747756 5867 53 37 0.69811320754717 0.00630645986023521
HPA HPA:0300412 lung; macrophages[≥Medium] 0.0358946093747756 4732 52 31 0.596153846153846 0.00655114116652578
HPA HPA:0170000 endometrium 2 0.0364038408376747 6755 53 41 0.773584905660377 0.00606957809030348
HPA HPA:0570781 testis; preleptotene spermatocytes[≥Low] 0.0364038408376747 1636 19 7 0.368421052631579 0.00427872860635697
HPA HPA:0420053 salivary gland; glandular cells[High] 0.0371048552403372 1418 53 13 0.245283018867925 0.00916784203102962
HPA HPA:0060000 bronchus 0.0375090799190437 7277 46 38 0.826086956521739 0.00522193211488251
HPA HPA:0500652 soft tissue 1; fibroblasts[≥Medium] 0.0379371142353556 2649 52 20 0.384615384615385 0.00755001887504719
HPA HPA:0510652 soft tissue 2; fibroblasts[≥Medium] 0.0379371142353556 2543 44 17 0.386363636363636 0.00668501769563508
HPA HPA:0110221 cervix, uterine; squamous epithelial cells[≥Low] 0.0379371142353556 5325 42 28 0.666666666666667 0.00525821596244131
HPA HPA:0050000 breast 0.0389671931767153 7026 46 37 0.804347826086957 0.00526615428408767
HPA HPA:0620222 vagina; squamous epithelial cells[≥Medium] 0.0390955994845151 3945 41 22 0.536585365853659 0.0055766793409379
HPA HPA:0180052 epididymis; glandular cells[≥Medium] 0.0393613215164929 5560 61 40 0.655737704918033 0.00719424460431655
HPA HPA:0160253 endometrium 1; cells in endometrial stroma[High] 0.0410619315852743 393 76 7 0.0921052631578947 0.0178117048346056
HPA HPA:0430052 seminal vesicle; glandular cells[≥Medium] 0.0410619315852743 5096 53 33 0.622641509433962 0.0064756671899529
HPA HPA:0620000 vagina 0.0411675133588555 5868 39 28 0.717948717948718 0.00477164280845262
HPA HPA:0080132 caudate; neuronal cells[≥Medium] 0.0411675133588555 4022 45 24 0.533333333333333 0.00596718050721034
HPA HPA:0620221 vagina; squamous epithelial cells[≥Low] 0.0411675133588555 5868 39 28 0.717948717948718 0.00477164280845262
HPA HPA:0380521 placenta; trophoblastic cells[≥Low] 0.0436655768119862 6388 53 39 0.735849056603774 0.00610519724483406
HPA HPA:0090953 cerebellum; Purkinje cells - dendrites[High] 0.0449738667111623 108 61 3 0.0491803278688525 0.0277777777777778
HPA HPA:0090901 cerebellum; Bergmann glia - cytoplasm/membrane[≥Low] 0.0459897141985969 106 63 3 0.0476190476190476 0.0283018867924528
HPA HPA:0130243 colon; peripheral nerve/ganglion[High] 0.0459897141985969 801 48 8 0.166666666666667 0.00998751560549313
HPA HPA:0050011 breast; adipocytes[≥Low] 0.0464615734654291 2725 78 28 0.358974358974359 0.0102752293577982
HPA HPA:0180051 epididymis; glandular cells[≥Low] 0.0466752555392604 7171 58 46 0.793103448275862 0.00641472597964022
HPA HPA:0180000 epididymis 0.0466752555392604 7171 58 46 0.793103448275862 0.00641472597964022
HPA HPA:0250133 hippocampus; neuronal cells[High] 0.0472472078242377 1210 45 10 0.222222222222222 0.00826446280991736
KEGG KEGG:04612 Antigen processing and presentation 2.58349720984502e-18 69 60 16 0.266666666666667 0.231884057971014
KEGG KEGG:04141 Protein processing in endoplasmic reticulum 1.51159191647097e-09 170 40 12 0.3 0.0705882352941176
KEGG KEGG:05134 Legionellosis 7.55644880456302e-08 57 49 8 0.163265306122449 0.140350877192982
KEGG KEGG:05330 Allograft rejection 3.31766347950998e-07 34 18 5 0.277777777777778 0.147058823529412
KEGG KEGG:05332 Graft-versus-host disease 4.14087041190837e-07 37 18 5 0.277777777777778 0.135135135135135
KEGG KEGG:04940 Type I diabetes mellitus 5.18784872675333e-07 40 18 5 0.277777777777778 0.125
KEGG KEGG:05320 Autoimmune thyroid disease 1.27297624480475e-06 49 18 5 0.277777777777778 0.102040816326531
KEGG KEGG:05416 Viral myocarditis 2.21009884403021e-06 56 18 5 0.277777777777778 0.0892857142857143
KEGG KEGG:05169 Epstein-Barr virus infection 4.10567803034523e-06 198 49 10 0.204081632653061 0.0505050505050505
KEGG KEGG:05145 Toxoplasmosis 4.10567803034523e-06 109 49 8 0.163265306122449 0.073394495412844
KEGG KEGG:04145 Phagosome 2.01537824479601e-05 147 32 7 0.21875 0.0476190476190476
KEGG KEGG:04142 Lysosome 2.18100229536373e-05 128 91 10 0.10989010989011 0.078125
KEGG KEGG:04915 Estrogen signaling pathway 4.35071492558611e-05 137 15 5 0.333333333333333 0.0364963503649635
KEGG KEGG:05167 Kaposi sarcoma-associated herpesvirus infection 5.35106946736382e-05 193 6 4 0.666666666666667 0.0207253886010363
KEGG KEGG:05166 Human T-cell leukemia virus 1 infection 5.38351752187054e-05 216 18 6 0.333333333333333 0.0277777777777778
KEGG KEGG:04144 Endocytosis 8.39546589720846e-05 252 17 6 0.352941176470588 0.0238095238095238
KEGG KEGG:04514 Cell adhesion molecules 0.000124222638369665 146 18 5 0.277777777777778 0.0342465753424658
KEGG KEGG:04659 Th17 cell differentiation 0.000308328131843753 104 30 5 0.166666666666667 0.0480769230769231
KEGG KEGG:05170 Human immunodeficiency virus 1 infection 0.000308328131843753 210 49 8 0.163265306122449 0.0380952380952381
KEGG KEGG:03040 Spliceosome 0.000811808034120352 150 41 6 0.146341463414634 0.04
KEGG KEGG:04213 Longevity regulating pathway - multiple species 0.00141965233220186 62 15 3 0.2 0.0483870967741935
KEGG KEGG:04657 IL-17 signaling pathway 0.00158336298730042 92 49 5 0.102040816326531 0.0543478260869565
KEGG KEGG:05163 Human cytomegalovirus infection 0.00248129117952297 223 49 7 0.142857142857143 0.031390134529148
KEGG KEGG:05162 Measles 0.0032036444097432 139 39 5 0.128205128205128 0.0359712230215827
KEGG KEGG:05168 Herpes simplex virus 1 infection 0.0032036444097432 494 18 6 0.333333333333333 0.0121457489878543
KEGG KEGG:05310 Asthma 0.00333216182811424 27 49 3 0.0612244897959184 0.111111111111111
KEGG KEGG:05215 Prostate cancer 0.00401957779587076 97 34 4 0.117647058823529 0.0412371134020619
KEGG KEGG:05140 Leishmaniasis 0.00495522698003306 72 49 4 0.0816326530612245 0.0555555555555556
KEGG KEGG:00511 Other glycan degradation 0.00523098917310821 18 91 3 0.032967032967033 0.166666666666667
KEGG KEGG:04010 MAPK signaling pathway 0.00919788877945869 294 49 7 0.142857142857143 0.0238095238095238
KEGG KEGG:05164 Influenza A 0.00919788877945869 169 62 6 0.0967741935483871 0.0355029585798817
KEGG KEGG:05203 Viral carcinogenesis 0.00929763470965499 202 53 6 0.113207547169811 0.0297029702970297
KEGG KEGG:04650 Natural killer cell mediated cytotoxicity 0.00929763470965499 123 17 3 0.176470588235294 0.024390243902439
KEGG KEGG:05132 Salmonella infection 0.0157836164314959 249 49 6 0.122448979591837 0.0240963855421687
KEGG KEGG:05152 Tuberculosis 0.0159528965460159 175 49 5 0.102040816326531 0.0285714285714286
KEGG KEGG:04218 Cellular senescence 0.0159528965460159 156 17 3 0.176470588235294 0.0192307692307692
KEGG KEGG:04658 Th1 and Th2 cell differentiation 0.0163556986977558 89 30 3 0.1 0.0337078651685393
KEGG KEGG:04920 Adipocytokine signaling pathway 0.0183810369952013 69 81 4 0.0493827160493827 0.0579710144927536
KEGG KEGG:05321 Inflammatory bowel disease 0.0217646394490679 62 49 3 0.0612244897959184 0.0483870967741935
KEGG KEGG:05020 Prion disease 0.0249158051245013 273 51 6 0.117647058823529 0.021978021978022
KEGG KEGG:00600 Sphingolipid metabolism 0.0394955002625056 49 80 3 0.0375 0.0612244897959184
MIRNA MIRNA:hsa-miR-615-3p hsa-miR-615-3p 0.00191843841925866 891 16 8 0.5 0.00897867564534231
MIRNA MIRNA:hsa-miR-544b hsa-miR-544b 0.00928946067970611 202 39 6 0.153846153846154 0.0297029702970297
MIRNA MIRNA:hsa-miR-340-5p hsa-miR-340-5p 0.0101620343468649 340 16 5 0.3125 0.0147058823529412
MIRNA MIRNA:hsa-miR-5590-3p hsa-miR-5590-3p 0.0108277793874719 212 63 7 0.111111111111111 0.0330188679245283
MIRNA MIRNA:hsa-miR-142-5p hsa-miR-142-5p 0.0124168365845079 225 63 7 0.111111111111111 0.0311111111111111
MIRNA MIRNA:hsa-miR-6822-5p hsa-miR-6822-5p 0.0124168365845079 72 17 3 0.176470588235294 0.0416666666666667
MIRNA MIRNA:hsa-miR-6750-5p hsa-miR-6750-5p 0.0124168365845079 72 17 3 0.176470588235294 0.0416666666666667
MIRNA MIRNA:hsa-miR-656-3p hsa-miR-656-3p 0.0124168365845079 124 26 4 0.153846153846154 0.032258064516129
MIRNA MIRNA:hsa-miR-15b-5p hsa-miR-15b-5p 0.0166971236932852 760 78 13 0.166666666666667 0.0171052631578947
MIRNA MIRNA:hsa-miR-106b-5p hsa-miR-106b-5p 0.0166971236932852 1084 29 9 0.310344827586207 0.00830258302583026
MIRNA MIRNA:hsa-miR-324-3p hsa-miR-324-3p 0.0171350063829022 336 14 4 0.285714285714286 0.0119047619047619
MIRNA MIRNA:hsa-miR-183-5p hsa-miR-183-5p 0.0171350063829022 347 13 4 0.307692307692308 0.0115273775216138
MIRNA MIRNA:hsa-miR-130b-3p hsa-miR-130b-3p 0.0171350063829022 571 4 3 0.75 0.00525394045534151
MIRNA MIRNA:hsa-miR-148a-3p hsa-miR-148a-3p 0.0171350063829022 212 38 5 0.131578947368421 0.0235849056603774
MIRNA MIRNA:hsa-miR-6810-5p hsa-miR-6810-5p 0.0171350063829022 105 17 3 0.176470588235294 0.0285714285714286
MIRNA MIRNA:hsa-miR-20b-5p hsa-miR-20b-5p 0.0175840763214608 911 29 8 0.275862068965517 0.00878155872667398
MIRNA MIRNA:hsa-miR-296-3p hsa-miR-296-3p 0.0175840763214608 255 19 4 0.210526315789474 0.0156862745098039
MIRNA MIRNA:hsa-miR-519d-3p hsa-miR-519d-3p 0.0175840763214608 900 29 8 0.275862068965517 0.00888888888888889
MIRNA MIRNA:hsa-miR-17-5p hsa-miR-17-5p 0.0175840763214608 1174 29 9 0.310344827586207 0.00766609880749574
MIRNA MIRNA:hsa-miR-582-5p hsa-miR-582-5p 0.0185827810211957 149 34 4 0.117647058823529 0.0268456375838926
MIRNA MIRNA:hsa-miR-140-3p hsa-miR-140-3p 0.0185827810211957 221 63 6 0.0952380952380952 0.0271493212669683
MIRNA MIRNA:hsa-miR-15a-5p hsa-miR-15a-5p 0.0185827810211957 717 78 12 0.153846153846154 0.0167364016736402
MIRNA MIRNA:hsa-miR-16-5p hsa-miR-16-5p 0.0185827810211957 1556 78 19 0.243589743589744 0.0122107969151671
MIRNA MIRNA:hsa-miR-2115-3p hsa-miR-2115-3p 0.0185827810211957 88 56 4 0.0714285714285714 0.0454545454545455
MIRNA MIRNA:hsa-miR-152-3p hsa-miR-152-3p 0.0210969437325685 157 34 4 0.117647058823529 0.0254777070063694
MIRNA MIRNA:hsa-miR-6073 hsa-miR-6073 0.0211386079379683 95 24 3 0.125 0.0315789473684211
MIRNA MIRNA:hsa-miR-93-5p hsa-miR-93-5p 0.0211386079379683 1213 30 9 0.3 0.00741962077493817
MIRNA MIRNA:hsa-miR-4670-3p hsa-miR-4670-3p 0.0214552003379352 89 26 3 0.115384615384615 0.0337078651685393
MIRNA MIRNA:hsa-miR-1226-3p hsa-miR-1226-3p 0.0216456297237185 226 11 3 0.272727272727273 0.0132743362831858
MIRNA MIRNA:hsa-miR-361-5p hsa-miR-361-5p 0.0241722963849541 160 16 3 0.1875 0.01875
MIRNA MIRNA:hsa-miR-4796-3p hsa-miR-4796-3p 0.0241722963849541 285 21 4 0.19047619047619 0.0140350877192982
MIRNA MIRNA:hsa-miR-10a-5p hsa-miR-10a-5p 0.0271908498053847 461 14 4 0.285714285714286 0.00867678958785249
MIRNA MIRNA:hsa-miR-20a-5p hsa-miR-20a-5p 0.027685278588797 1064 29 8 0.275862068965517 0.0075187969924812
MIRNA MIRNA:hsa-miR-520d-5p hsa-miR-520d-5p 0.0284498487258598 164 38 4 0.105263157894737 0.024390243902439
MIRNA MIRNA:hsa-miR-524-5p hsa-miR-524-5p 0.0316279091925992 171 38 4 0.105263157894737 0.0233918128654971
MIRNA MIRNA:hsa-miR-197-3p hsa-miR-197-3p 0.032531553626792 407 75 8 0.106666666666667 0.0196560196560197
MIRNA MIRNA:hsa-miR-484 hsa-miR-484 0.032531553626792 890 81 13 0.160493827160494 0.0146067415730337
MIRNA MIRNA:hsa-miR-4641 hsa-miR-4641 0.032531553626792 52 57 3 0.0526315789473684 0.0576923076923077
MIRNA MIRNA:hsa-miR-130a-3p hsa-miR-130a-3p 0.032531553626792 398 77 8 0.103896103896104 0.0201005025125628
MIRNA MIRNA:hsa-miR-6838-5p hsa-miR-6838-5p 0.0347991273107774 431 28 5 0.178571428571429 0.0116009280742459
MIRNA MIRNA:hsa-miR-4263 hsa-miR-4263 0.0348687296671231 94 33 3 0.0909090909090909 0.0319148936170213
MIRNA MIRNA:hsa-miR-519b-3p hsa-miR-519b-3p 0.0410990401836197 342 75 7 0.0933333333333333 0.0204678362573099
MIRNA MIRNA:hsa-miR-1200 hsa-miR-1200 0.0410990401836197 159 81 5 0.0617283950617284 0.0314465408805031
MIRNA MIRNA:hsa-miR-186-5p hsa-miR-186-5p 0.0410990401836197 749 44 8 0.181818181818182 0.0106809078771696
MIRNA MIRNA:hsa-miR-101-3p hsa-miR-101-3p 0.0410990401836197 391 34 5 0.147058823529412 0.0127877237851662
MIRNA MIRNA:hsa-miR-519c-3p hsa-miR-519c-3p 0.0410990401836197 348 75 7 0.0933333333333333 0.0201149425287356
MIRNA MIRNA:hsa-miR-519a-3p hsa-miR-519a-3p 0.0410990401836197 347 75 7 0.0933333333333333 0.0201729106628242
MIRNA MIRNA:hsa-miR-497-5p hsa-miR-497-5p 0.0410990401836197 460 28 5 0.178571428571429 0.0108695652173913
MIRNA MIRNA:hsa-miR-4496 hsa-miR-4496 0.0410990401836197 118 29 3 0.103448275862069 0.0254237288135593
MIRNA MIRNA:hsa-miR-424-5p hsa-miR-424-5p 0.0410990401836197 470 28 5 0.178571428571429 0.0106382978723404
MIRNA MIRNA:hsa-miR-195-5p hsa-miR-195-5p 0.0410990401836197 639 78 10 0.128205128205128 0.0156494522691706
MIRNA MIRNA:hsa-miR-1304-5p hsa-miR-1304-5p 0.0421681392973121 133 28 3 0.107142857142857 0.0225563909774436
MIRNA MIRNA:hsa-miR-148b-3p hsa-miR-148b-3p 0.0424751431797646 402 34 5 0.147058823529412 0.0124378109452736
MIRNA MIRNA:hsa-miR-3133 hsa-miR-3133 0.0438616842527169 187 44 4 0.0909090909090909 0.0213903743315508
MIRNA MIRNA:hsa-miR-526b-3p hsa-miR-526b-3p 0.0444874627294023 635 14 4 0.285714285714286 0.0062992125984252
MIRNA MIRNA:hsa-miR-205-5p hsa-miR-205-5p 0.0444874627294023 182 22 3 0.136363636363636 0.0164835164835165
MIRNA MIRNA:hsa-miR-3140-5p hsa-miR-3140-5p 0.0444874627294023 52 76 3 0.0394736842105263 0.0576923076923077
MIRNA MIRNA:hsa-miR-330-5p hsa-miR-330-5p 0.0445474897016554 121 69 4 0.0579710144927536 0.0330578512396694
MIRNA MIRNA:hsa-miR-3609 hsa-miR-3609 0.046017898366569 319 14 3 0.214285714285714 0.00940438871473354
MIRNA MIRNA:hsa-miR-3928-3p hsa-miR-3928-3p 0.046017898366569 121 34 3 0.0882352941176471 0.0247933884297521
MIRNA MIRNA:hsa-miR-4660 hsa-miR-4660 0.046017898366569 77 55 3 0.0545454545454545 0.038961038961039
MIRNA MIRNA:hsa-miR-655-5p hsa-miR-655-5p 0.046017898366569 122 35 3 0.0857142857142857 0.0245901639344262
MIRNA MIRNA:hsa-miR-583 hsa-miR-583 0.046017898366569 155 28 3 0.107142857142857 0.0193548387096774
MIRNA MIRNA:hsa-miR-7156-3p hsa-miR-7156-3p 0.046017898366569 136 63 4 0.0634920634920635 0.0294117647058824
MIRNA MIRNA:hsa-miR-548ah-5p hsa-miR-548ah-5p 0.046017898366569 318 14 3 0.214285714285714 0.00943396226415094
MIRNA MIRNA:hsa-miR-3616-5p hsa-miR-3616-5p 0.046017898366569 117 75 4 0.0533333333333333 0.0341880341880342
MIRNA MIRNA:hsa-miR-6761-5p hsa-miR-6761-5p 0.046017898366569 108 39 3 0.0769230769230769 0.0277777777777778
MIRNA MIRNA:hsa-miR-493-3p hsa-miR-493-3p 0.0470891790226927 87 50 3 0.06 0.0344827586206897
MIRNA MIRNA:hsa-miR-573 hsa-miR-573 0.0481175347312989 121 75 4 0.0533333333333333 0.0330578512396694
MIRNA MIRNA:hsa-miR-6832-5p hsa-miR-6832-5p 0.0481933141232332 267 35 4 0.114285714285714 0.0149812734082397
MIRNA MIRNA:hsa-miR-106a-5p hsa-miR-106a-5p 0.0481933141232332 709 14 4 0.285714285714286 0.00564174894217207
MIRNA MIRNA:hsa-miR-1244 hsa-miR-1244 0.0481933141232332 59 77 3 0.038961038961039 0.0508474576271186
REAC REAC:R-HSA-3371568 Attenuation phase 4.85590473400358e-12 14 15 6 0.4 0.428571428571429
REAC REAC:R-HSA-3371571 HSF1-dependent transactivation 1.08027317327447e-10 24 15 6 0.4 0.25
REAC REAC:R-HSA-913531 Interferon Signaling 1.51758972938277e-09 191 18 9 0.5 0.0471204188481675
REAC REAC:R-HSA-3371497 HSP90 chaperone cycle for steroid hormone receptors (SHR) 2.2863421710796e-09 57 22 7 0.318181818181818 0.12280701754386
REAC REAC:R-HSA-1236977 Endosomal/Vacuolar pathway 2.77555461708918e-09 11 25 5 0.2 0.454545454545455
REAC REAC:R-HSA-9613829 Chaperone Mediated Autophagy 4.95488416470298e-09 22 14 5 0.357142857142857 0.227272727272727
REAC REAC:R-HSA-983170 Antigen Presentation: Folding, assembly and peptide loading of class I MHC 2.99409557970912e-08 25 40 6 0.15 0.24
REAC REAC:R-HSA-1280215 Cytokine Signaling in Immune system 5.71926609154359e-08 842 18 12 0.666666666666667 0.0142517814726841
REAC REAC:R-HSA-3371556 Cellular response to heat stress 8.59922272217385e-08 87 15 6 0.4 0.0689655172413793
REAC REAC:R-HSA-1236975 Antigen processing-Cross presentation 1.089162897026e-07 99 38 8 0.210526315789474 0.0808080808080808
REAC REAC:R-HSA-1236974 ER-Phagosome pathway 1.28792333585624e-07 83 17 6 0.352941176470588 0.072289156626506
REAC REAC:R-HSA-5637815 Signaling by Ligand-Responsive EGFR Variants in Cancer 1.65820579315122e-07 17 3 3 1 0.176470588235294
REAC REAC:R-HSA-1236382 Constitutive Signaling by Ligand-Responsive EGFR Cancer Variants 1.65820579315122e-07 17 3 3 1 0.176470588235294
REAC REAC:R-HSA-877300 Interferon gamma signaling 1.91351790459289e-07 87 18 6 0.333333333333333 0.0689655172413793
REAC REAC:R-HSA-168256 Immune System 1.91351790459289e-07 2139 42 26 0.619047619047619 0.0121552127162225
REAC REAC:R-HSA-1643713 Signaling by EGFR in Cancer 3.50890367423902e-07 23 3 3 1 0.130434782608696
REAC REAC:R-HSA-8863795 Downregulation of ERBB2 signaling 5.45443557825046e-07 27 3 3 1 0.111111111111111
REAC REAC:R-HSA-9637628 Modulation by Mtb of host immune system 7.38217080344566e-07 7 10 3 0.3 0.428571428571429
REAC REAC:R-HSA-168249 Innate Immune System 1.27606799878392e-06 1073 42 18 0.428571428571429 0.0167753960857409
REAC REAC:R-HSA-9646399 Aggrephagy 2.09923976337082e-06 44 3 3 1 0.0681818181818182
REAC REAC:R-HSA-1227986 Signaling by ERBB2 2.18736852420096e-06 46 3 3 1 0.0652173913043478
REAC REAC:R-HSA-6798695 Neutrophil degranulation 2.18736852420096e-06 474 39 12 0.307692307692308 0.0253164556962025
REAC REAC:R-HSA-450408 AUF1 (hnRNP D0) binds and destabilizes mRNA 2.46261850125705e-06 54 23 5 0.217391304347826 0.0925925925925926
REAC REAC:R-HSA-8852276 The role of GTSE1 in G2/M progression after G2 checkpoint 2.59135146069944e-06 79 7 4 0.571428571428571 0.0506329113924051
REAC REAC:R-HSA-2262752 Cellular responses to stress 5.67414912985493e-06 546 15 8 0.533333333333333 0.0146520146520147
REAC REAC:R-HSA-8953897 Cellular responses to external stimuli 6.63195767136556e-06 560 15 8 0.533333333333333 0.0142857142857143
REAC REAC:R-HSA-9678108 SARS-CoV-1 Infection 8.84659222463489e-06 50 4 3 0.75 0.06
REAC REAC:R-HSA-9663891 Selective autophagy 8.98121928777361e-06 80 3 3 1 0.0375
REAC REAC:R-HSA-2565942 Regulation of PLK1 Activity at G2/M Transition 1.0437023629726e-05 85 3 3 1 0.0352941176470588
REAC REAC:R-HSA-202424 Downstream TCR signaling 1.44084912817713e-05 98 35 6 0.171428571428571 0.0612244897959184
REAC REAC:R-HSA-983169 Class I MHC mediated antigen processing & presentation 1.60561083792304e-05 370 40 10 0.25 0.027027027027027
REAC REAC:R-HSA-450531 Regulation of mRNA stability by proteins that bind AU-rich elements 1.75256580507496e-05 86 23 5 0.217391304347826 0.0581395348837209
REAC REAC:R-HSA-9612973 Autophagy 1.75256580507496e-05 149 14 5 0.357142857142857 0.0335570469798658
REAC REAC:R-HSA-5687128 MAPK6/MAPK4 signaling 2.02043066557311e-05 89 23 5 0.217391304347826 0.0561797752808989
REAC REAC:R-HSA-168898 Toll-like Receptor Cascades 2.70681508384004e-05 152 42 7 0.166666666666667 0.0460526315789474
REAC REAC:R-HSA-9635486 Infection with Mycobacterium tuberculosis 2.70681508384004e-05 27 10 3 0.3 0.111111111111111
REAC REAC:R-HSA-3371453 Regulation of HSF1-mediated heat shock response 2.70681508384004e-05 67 15 4 0.266666666666667 0.0597014925373134
REAC REAC:R-HSA-1632852 Macroautophagy 2.70681508384004e-05 134 3 3 1 0.0223880597014925
REAC REAC:R-HSA-9679506 SARS-CoV Infections 2.70681508384004e-05 85 4 3 0.75 0.0352941176470588
REAC REAC:R-HSA-202403 TCR signaling 3.06511581712948e-05 120 35 6 0.171428571428571 0.05
REAC REAC:R-HSA-8866654 E3 ubiquitin ligases ubiquitinate target proteins 3.06511581712948e-05 53 6 3 0.5 0.0566037735849057
REAC REAC:R-HSA-69275 G2/M Transition 4.29034866422916e-05 196 7 4 0.571428571428571 0.0204081632653061
REAC REAC:R-HSA-453274 Mitotic G2-G2/M phases 4.34078528478713e-05 198 7 4 0.571428571428571 0.0202020202020202
REAC REAC:R-HSA-1280218 Adaptive Immune System 4.34078528478713e-05 800 40 13 0.325 0.01625
REAC REAC:R-HSA-168643 Nucleotide-binding domain, leucine rich repeat containing receptor (NLR) signaling pathways 4.34078528478713e-05 55 7 3 0.428571428571429 0.0545454545454545
REAC REAC:R-HSA-449147 Signaling by Interleukins 4.34078528478713e-05 446 49 11 0.224489795918367 0.0246636771300448
REAC REAC:R-HSA-8852135 Protein ubiquitination 4.6585715215456e-05 73 6 3 0.5 0.0410958904109589
REAC REAC:R-HSA-445989 TAK1 activates NFkB by phosphorylation and activation of IKKs complex 5.04474105999516e-05 32 42 4 0.0952380952380952 0.125
REAC REAC:R-HSA-9615710 Late endosomal microautophagy 6.87691867424205e-05 34 14 3 0.214285714285714 0.0882352941176471
REAC REAC:R-HSA-168142 Toll Like Receptor 10 (TLR10) Cascade 9.66867349896674e-05 84 42 5 0.119047619047619 0.0595238095238095
REAC REAC:R-HSA-975871 MyD88 cascade initiated on plasma membrane 9.66867349896674e-05 84 42 5 0.119047619047619 0.0595238095238095
REAC REAC:R-HSA-168176 Toll Like Receptor 5 (TLR5) Cascade 9.66867349896674e-05 84 42 5 0.119047619047619 0.0595238095238095
REAC REAC:R-HSA-8953854 Metabolism of RNA 0.000114043739954097 658 16 7 0.4375 0.0106382978723404
REAC REAC:R-HSA-975138 TRAF6 mediated induction of NFkB and MAP kinases upon TLR7/8 or 9 activation 0.000117979768897661 90 42 5 0.119047619047619 0.0555555555555556
REAC REAC:R-HSA-168181 Toll Like Receptor 7/8 (TLR7/8) Cascade 0.000120610032625034 91 42 5 0.119047619047619 0.0549450549450549
REAC REAC:R-HSA-975155 MyD88 dependent cascade initiated on endosome 0.000120610032625034 91 42 5 0.119047619047619 0.0549450549450549
REAC REAC:R-HSA-168164 Toll Like Receptor 3 (TLR3) Cascade 0.000125885851260131 92 42 5 0.119047619047619 0.0543478260869565
REAC REAC:R-HSA-977225 Amyloid fiber formation 0.000134213771405093 73 27 4 0.148148148148148 0.0547945205479452
REAC REAC:R-HSA-166058 MyD88:MAL(TIRAP) cascade initiated on plasma membrane 0.000134213771405093 94 42 5 0.119047619047619 0.0531914893617021
REAC REAC:R-HSA-168188 Toll Like Receptor TLR6:TLR2 Cascade 0.000134213771405093 94 42 5 0.119047619047619 0.0531914893617021
REAC REAC:R-HSA-5663205 Infectious disease 0.000134659112728018 815 10 6 0.6 0.00736196319018405
REAC REAC:R-HSA-168138 Toll Like Receptor 9 (TLR9) Cascade 0.000137656916698807 95 42 5 0.119047619047619 0.0526315789473684
REAC REAC:R-HSA-166166 MyD88-independent TLR4 cascade 0.000141198391699561 96 42 5 0.119047619047619 0.0520833333333333
REAC REAC:R-HSA-937061 TRIF(TICAM1)-mediated TLR4 signaling 0.000141198391699561 96 42 5 0.119047619047619 0.0520833333333333
REAC REAC:R-HSA-168179 Toll Like Receptor TLR1:TLR2 Cascade 0.000143965871895229 97 42 5 0.119047619047619 0.0515463917525773
REAC REAC:R-HSA-181438 Toll Like Receptor 2 (TLR2) Cascade 0.000143965871895229 97 42 5 0.119047619047619 0.0515463917525773
REAC REAC:R-HSA-5607764 CLEC7A (Dectin-1) signaling 0.000143965871895229 97 42 5 0.119047619047619 0.0515463917525773
REAC REAC:R-HSA-9018519 Estrogen-dependent gene expression 0.000146787677051957 112 7 3 0.428571428571429 0.0267857142857143
REAC REAC:R-HSA-5663202 Diseases of signal transduction by growth factor receptors and second messengers 0.000156504744088477 371 3 3 1 0.00808625336927224
REAC REAC:R-HSA-68886 M Phase 0.000156504744088477 371 3 3 1 0.00808625336927224
REAC REAC:R-HSA-9020702 Interleukin-1 signaling 0.000164015134696202 101 42 5 0.119047619047619 0.0495049504950495
REAC REAC:R-HSA-1169091 Activation of NF-kappaB in B cells 0.000221419967526304 67 35 4 0.114285714285714 0.0597014925373134
REAC REAC:R-HSA-1169408 ISG15 antiviral mechanism 0.000234783535955709 70 13 3 0.230769230769231 0.0428571428571429
REAC REAC:R-HSA-5676590 NIK-->noncanonical NF-kB signaling 0.000244914509912996 59 42 4 0.0952380952380952 0.0677966101694915
REAC REAC:R-HSA-5607761 Dectin-1 mediated noncanonical NF-kB signaling 0.000255105203613183 60 42 4 0.0952380952380952 0.0666666666666667
REAC REAC:R-HSA-5668541 TNFR2 non-canonical NF-kB pathway 0.000259600829051137 100 49 5 0.102040816326531 0.05
REAC REAC:R-HSA-9006934 Signaling by Receptor Tyrosine Kinases 0.000262736857572845 485 3 3 1 0.00618556701030928
REAC REAC:R-HSA-1169410 Antiviral mechanism by IFN-stimulated genes 0.000280621419200605 78 13 3 0.230769230769231 0.0384615384615385
REAC REAC:R-HSA-69278 Cell Cycle, Mitotic 0.000292570609074851 513 3 3 1 0.00584795321637427
REAC REAC:R-HSA-166016 Toll Like Receptor 4 (TLR4) Cascade 0.000325419761586895 126 42 5 0.119047619047619 0.0396825396825397
REAC REAC:R-HSA-1168372 Downstream signaling events of B Cell Receptor (BCR) 0.000325419761586895 80 35 4 0.114285714285714 0.05
REAC REAC:R-HSA-422475 Axon guidance 0.000336242143227895 549 3 3 1 0.00546448087431694
REAC REAC:R-HSA-909733 Interferon alpha/beta signaling 0.000349578046558787 66 17 3 0.176470588235294 0.0454545454545455
REAC REAC:R-HSA-9675108 Nervous system development 0.000362771864930301 574 3 3 1 0.00522648083623693
REAC REAC:R-HSA-8939211 ESR-mediated signaling 0.000371336059217911 181 7 3 0.428571428571429 0.0165745856353591
REAC REAC:R-HSA-198933 Immunoregulatory interactions between a Lymphoid and a non-Lymphoid cell 0.000375197920357525 181 17 4 0.235294117647059 0.0220994475138122
REAC REAC:R-HSA-162909 Host Interactions of HIV factors 0.000401871633247326 125 10 3 0.3 0.024
REAC REAC:R-HSA-5621481 C-type lectin receptors (CLRs) 0.00041200448041605 136 42 5 0.119047619047619 0.0367647058823529
REAC REAC:R-HSA-446652 Interleukin-1 family signaling 0.000435074454654438 138 42 5 0.119047619047619 0.036231884057971
REAC REAC:R-HSA-1640170 Cell Cycle 0.000466958607044048 642 3 3 1 0.00467289719626168
REAC REAC:R-HSA-5653656 Vesicle-mediated transport 0.000633779825482583 717 3 3 1 0.00418410041841004
REAC REAC:R-HSA-1643685 Disease 0.000796574594083693 1509 4 4 1 0.00265076209410205
REAC REAC:R-HSA-5683057 MAPK family signaling cascades 0.000850637702856072 308 23 5 0.217391304347826 0.0162337662337662
REAC REAC:R-HSA-9006931 Signaling by Nuclear Receptors 0.000857799244056368 255 7 3 0.428571428571429 0.0117647058823529
REAC REAC:R-HSA-162906 HIV Infection 0.0015447691723735 226 53 6 0.113207547169811 0.0265486725663717
REAC REAC:R-HSA-1266738 Developmental Biology 0.00176336464949764 1069 3 3 1 0.00280636108512629
REAC REAC:R-HSA-6785807 Interleukin-4 and Interleukin-13 signaling 0.00268397636216694 110 49 4 0.0816326530612245 0.0363636363636364
REAC REAC:R-HSA-72163 mRNA Splicing - Major Pathway 0.0035229371318156 178 16 3 0.1875 0.0168539325842697
REAC REAC:R-HSA-74160 Gene expression (Transcription) 0.00386601748544754 1435 3 3 1 0.00209059233449477
REAC REAC:R-HSA-72172 mRNA Splicing 0.00391374914038534 186 16 3 0.1875 0.0161290322580645
REAC REAC:R-HSA-2132295 MHC class II antigen presentation 0.00448273164359662 123 25 3 0.12 0.024390243902439
REAC REAC:R-HSA-597592 Post-translational protein modification 0.00525791603860128 1377 6 4 0.666666666666667 0.00290486564996369
REAC REAC:R-HSA-162582 Signal Transduction 0.00639105169684087 2705 4 4 1 0.00147874306839187
REAC REAC:R-HSA-72203 Processing of Capped Intron-Containing Pre-mRNA 0.00727981845896943 235 16 3 0.1875 0.0127659574468085
REAC REAC:R-HSA-1430728 Metabolism 0.0108978081805304 2070 3 3 1 0.00144927536231884
REAC REAC:R-HSA-392499 Metabolism of proteins 0.0109860002847876 1961 14 7 0.5 0.00356960734319225
REAC REAC:R-HSA-3108232 SUMO E3 ligases SUMOylate target proteins 0.0315320848399312 156 42 3 0.0714285714285714 0.0192307692307692
REAC REAC:R-HSA-2990846 SUMOylation 0.0345438715125576 162 42 3 0.0714285714285714 0.0185185185185185
REAC REAC:R-HSA-428157 Sphingolipid metabolism 0.0357777546007577 86 80 3 0.0375 0.0348837209302326
REAC REAC:R-HSA-167172 Transcription of the HIV genome 0.0357777546007577 71 97 3 0.0309278350515464 0.0422535211267606
TF TF:M09950_1 Factor: HSF1; motif: NRGAANNTTCYRGAA; match class: 1 3.43764706789553e-08 266 43 11 0.255813953488372 0.0413533834586466
TF TF:M11656_1 Factor: HSF1; motif: RGAANRTTCYRGAAN; match class: 1 3.43764706789553e-08 219 39 10 0.256410256410256 0.045662100456621
TF TF:M11654_1 Factor: HSF1; motif: RGAANRTTCYRGAAN; match class: 1 7.85563825988213e-08 113 23 7 0.304347826086957 0.0619469026548673
TF TF:M11655_1 Factor: HSF1; motif: NGAANGTTCKRGAAN; match class: 1 1.52507846856661e-07 93 31 7 0.225806451612903 0.0752688172043011
TF TF:M11655 Factor: HSF1; motif: NGAANGTTCKRGAAN 6.73144912459565e-07 1207 40 16 0.4 0.0132560066280033
TF TF:M07100_1 Factor: HSF1; motif: NTTCTRGAANNTTCY; match class: 1 2.87257801183441e-06 514 23 9 0.391304347826087 0.0175097276264591
TF TF:M01023_1 Factor: HSF1; motif: NTTCTRGAAVNTTCTYM; match class: 1 2.87257801183441e-06 254 43 9 0.209302325581395 0.0354330708661417
TF TF:M11656 Factor: HSF1; motif: RGAANRTTCYRGAAN 2.96408036362845e-06 2033 26 15 0.576923076923077 0.0073782587309395
TF TF:M11662 Factor: HSF2; motif: RGAANGTTCYRGAAN 4.85617712043967e-06 272 31 8 0.258064516129032 0.0294117647058824
TF TF:M11654 Factor: HSF1; motif: RGAANRTTCYRGAAN 1.57317348564518e-05 1353 40 15 0.375 0.0110864745011086
TF TF:M11658 Factor: HSF4; motif: RGAANNTTCYRGAAN 7.85798967392316e-05 400 31 8 0.258064516129032 0.02
TF TF:M07358 Factor: HSF2; motif: NGGAATNTTCTNGNRN 8.48516366519022e-05 576 31 9 0.290322580645161 0.015625
TF TF:M00287 Factor: NF-Y; motif: NNNRRCCAATSRGNNN 9.43347803930812e-05 1635 21 11 0.523809523809524 0.00672782874617737
TF TF:M07302 Factor: NF-Y; motif: RGCCAATCRGN 0.000109711317307668 1576 18 10 0.555555555555556 0.00634517766497462
TF TF:M11662_1 Factor: HSF2; motif: RGAANGTTCYRGAAN; match class: 1 0.000117264199141419 12 23 3 0.130434782608696 0.25
TF TF:M09950 Factor: HSF1; motif: NRGAANNTTCYRGAA 0.000117264199141419 2501 25 14 0.56 0.00559776089564174
TF TF:M04683 Factor: NF-YA; motif: YTCTSATTGGYYRN 0.000144628971653015 1657 18 10 0.555555555555556 0.00603500301750151
TF TF:M10005 Factor: NF-YA; motif: NYRRCCAATCAGAR 0.000156377570722859 2225 21 12 0.571428571428571 0.00539325842696629
TF TF:M07100 Factor: HSF1; motif: NTTCTRGAANNTTCY 0.000257402803982157 3350 45 22 0.488888888888889 0.00656716417910448
TF TF:M01023 Factor: HSF1; motif: NTTCTRGAAVNTTCTYM 0.000269036394409546 2721 25 14 0.56 0.00514516721793458
TF TF:M11658_1 Factor: HSF4; motif: RGAANNTTCYRGAAN; match class: 1 0.000389912104113964 19 23 3 0.130434782608696 0.157894736842105
TF TF:M09816 Factor: NFYA; motif: RRCCAATCAGN 0.000556133296392501 1969 18 10 0.555555555555556 0.00507872016251905
TF TF:M09956 Factor: IRF-1; motif: NAAANNGAAASTGAAASNRN 0.000604352452855151 317 25 6 0.24 0.0189274447949527
TF TF:M09957 Factor: IRF-2; motif: NAAANNGAAAGTGAAASTRN 0.000668511263302773 272 17 5 0.294117647058824 0.0183823529411765
TF TF:M00691_1 Factor: ATF-1; motif: CYYTGACGTCA; match class: 1 0.000725742491719418 854 7 5 0.714285714285714 0.00585480093676815
TF TF:M04788 Factor: IRF-1; motif: STTTCACTTTCNNT 0.000785540419007246 536 25 7 0.28 0.0130597014925373
TF TF:M10119 Factor: REX-1; motif: GGCMGCCATTTT 0.000889717031430829 1888 28 12 0.428571428571429 0.00635593220338983
TF TF:M02106 Factor: NF-YA; motif: CRGCCAATCAGNRN 0.000889717031430829 1741 21 10 0.476190476190476 0.00574382538770821
TF TF:M11392_1 Factor: Erg; motif: NACCGGAARYN; match class: 1 0.00156361065660483 3233 78 29 0.371794871794872 0.00896999690689762
TF TF:M00699_1 Factor: ICSBP; motif: RAARTGAAACTG; match class: 1 0.00167809404202361 47 17 3 0.176470588235294 0.0638297872340425
TF TF:M02107 Factor: NF-YC; motif: NRGCCAATYAGMGC 0.00194489330873391 1001 17 7 0.411764705882353 0.00699300699300699
TF TF:M11659 Factor: HSF4; motif: NGAANRTTCTAGAAN 0.00194489330873391 329 31 6 0.193548387096774 0.0182370820668693
TF TF:M02107_1 Factor: NF-YC; motif: NRGCCAATYAGMGC; match class: 1 0.00194489330873391 58 15 3 0.2 0.0517241379310345
TF TF:M00775 Factor: NF-Y; motif: NNNNRRCCAATSR 0.00211990106400221 1428 95 20 0.210526315789474 0.0140056022408964
TF TF:M11657 Factor: HSF1; motif: NGAANRTTCKAGAAN 0.00211990106400221 337 31 6 0.193548387096774 0.0178041543026706
TF TF:M00641 Factor: HSF; motif: TTCCMGARGYTTC 0.00216546829860713 3599 16 11 0.6875 0.00305640455682134
TF TF:M10006 Factor: NF-YC; motif: NNRRCCAATCAGNR 0.00233159291000124 2510 21 11 0.523809523809524 0.00438247011952191
TF TF:M07222_1 Factor: NFYA; motif: AGNSYKCTGATTGGTNNR; match class: 1 0.00250535606051833 66 15 3 0.2 0.0454545454545455
TF TF:M04008 Factor: HSF1; motif: TTCTAGAAYNTTC 0.00265661917762778 358 31 6 0.193548387096774 0.0167597765363128
TF TF:M01244 Factor: HSF2; motif: GAANRTTCTAGAA 0.00275710608491413 582 40 8 0.2 0.013745704467354
TF TF:M11400_1 Factor: Fli-1; motif: NACCGGAARTN; match class: 1 0.00313119381578968 4201 81 34 0.419753086419753 0.00809331111640086
TF TF:M00185 Factor: NF-Y; motif: TRRCCAATSRN 0.00369463565882517 870 15 6 0.4 0.00689655172413793
TF TF:M07216 Factor: IRF1; motif: NNNYASTTTCACTTTCNNTTT 0.00375880859938561 440 17 5 0.294117647058824 0.0113636363636364
TF TF:M07222 Factor: NFYA; motif: AGNSYKCTGATTGGTNNR 0.00386665437218323 714 18 6 0.333333333333333 0.00840336134453781
TF TF:M03977_1 Factor: ETS1; motif: ACCGGAARYN; match class: 1 0.00431951706103859 4677 78 35 0.448717948717949 0.0074834295488561
TF TF:M08930_1 Factor: JUND:FRA-1; motif: RTGACGTMAY; match class: 1 0.00553528107010314 1607 4 4 1 0.00248911014312383
TF TF:M11396_1 Factor: Erg; motif: NACCGGAARTN; match class: 1 0.00568064021026331 4963 78 36 0.461538461538462 0.00725367721136409
TF TF:M04010 Factor: HSF4; motif: TTCTAGAANNTTC 0.00580301101079081 185 22 4 0.181818181818182 0.0216216216216216
TF TF:M00147_1 Factor: HSF2; motif: NGAANNWTCK; match class: 1 0.00622969079109637 4404 25 15 0.6 0.00340599455040872
TF TF:M00772 Factor: IRF; motif: RRAANTGAAASYGNV 0.00681036718479935 1029 21 7 0.333333333333333 0.00680272108843537
TF TF:M11221 Factor: CREB1; motif: RTGACGYGTCAN 0.00681036718479935 9677 37 30 0.810810810810811 0.0031001343391547
TF TF:M03975_1 Factor: ERG; motif: ACCGGAARTN; match class: 1 0.00681036718479935 4024 81 32 0.395061728395062 0.00795228628230616
TF TF:M01223_1 Factor: P50:P50; motif: NRGGGAMTNCCCN; match class: 1 0.00681036718479935 161 10 3 0.3 0.0186335403726708
TF TF:M08392_1 Factor: A-Myb:TBR2; motif: NNGTGNNNAACGG; match class: 1 0.00773318498007432 111 15 3 0.2 0.027027027027027
TF TF:M11664 Factor: IRF-2; motif: NGAAASYGAAAS 0.00773318498007432 1651 29 10 0.344827586206897 0.00605693519079346
TF TF:M09608 Factor: Erg; motif: NNACCGGAARTSN 0.00773318498007432 8152 85 53 0.623529411764706 0.00650147203140334
TF TF:M11402 Factor: Fli-1; motif: NACCGGAARTN 0.00933373658796481 3885 85 32 0.376470588235294 0.00823680823680824
TF TF:M00144_1 Factor: Pax-5; motif: RRMSWGANWYCTNRAGCGKRACSRYNSM; match class: 1 0.0102212814509847 7128 39 26 0.666666666666667 0.00364758698092031
TF TF:M00209 Factor: NF-Y; motif: NCTGATTGGYTASY 0.0102212814509847 3776 18 11 0.611111111111111 0.00291313559322034
TF TF:M07204 Factor: AR; motif: ARGAACANNNTGTNC 0.0111571673406176 4906 53 26 0.490566037735849 0.00529963310232368
TF TF:M10632 Factor: Nkx2-8; motif: STCGTTGAN 0.0111571673406176 4871 45 23 0.511111111111111 0.00472182303428454
TF TF:M02072 Factor: Pet-1; motif: ACCGGAWRTN 0.0113808381932069 2395 44 15 0.340909090909091 0.00626304801670146
TF TF:M11800_1 Factor: NR1B2; motif: RAGGTCRTGACCTY; match class: 1 0.0113808381932069 987 89 14 0.157303370786517 0.0141843971631206
TF TF:M10635_1 Factor: Nkx2-3; motif: GNCGTTRAG; match class: 1 0.0113808381932069 703 15 5 0.333333333333333 0.00711237553342817
TF TF:M08020_1 Factor: YY2; motif: NNCCGCCATTW; match class: 1 0.0122742647834051 72 28 3 0.107142857142857 0.0416666666666667
TF TF:M10094_1 Factor: RelA-p65; motif: NWGGGRATTTCCMN; match class: 1 0.0132574442067825 242 42 5 0.119047619047619 0.0206611570247934
TF TF:M11222_1 Factor: CREB1; motif: NRTGAYGTCAYN; match class: 1 0.0139712856448173 1088 3 3 1 0.00275735294117647
TF TF:M02061 Factor: ERF; motif: ACCGGAARYN 0.0156053668317534 2579 61 19 0.311475409836066 0.00736719658782474
TF TF:M11733 Factor: PXR; motif: NYGAACTSNNTGAACTC 0.0162182714826774 2983 30 13 0.433333333333333 0.00435802883003688
TF TF:M11221_1 Factor: CREB1; motif: RTGACGYGTCAN; match class: 1 0.0168269286985274 5695 36 21 0.583333333333333 0.00368744512730465
TF TF:M02017 Factor: HSF1; motif: GAANNTTCTRGNAN 0.0168269286985274 4046 61 25 0.409836065573771 0.00617894216510133
TF TF:M09867_1 Factor: ATF-2; motif: RRTGANGTCAY; match class: 1 0.0168269286985274 1183 3 3 1 0.00253592561284869
TF TF:M08887 Factor: IRF; motif: NNGAAANTGAAANN 0.0179189817390923 1267 21 7 0.333333333333333 0.00552486187845304
TF TF:M11216_1 Factor: CREB1; motif: NRTGATGTCAYN; match class: 1 0.0180013730760793 1220 3 3 1 0.00245901639344262
TF TF:M00025_1 Factor: Elk-1; motif: NNNNCCGGAARTNN; match class: 1 0.0182803038531502 4639 79 33 0.417721518987342 0.00711360206941151
TF TF:M11765 Factor: TR2; motif: NRGGTCRYGACCYN 0.0200049623838926 3058 62 21 0.338709677419355 0.00686723348593852
TF TF:M11218_1 Factor: CREB1; motif: NRTGAYGCGTN; match class: 1 0.0220780260229871 2438 37 13 0.351351351351351 0.00533223954060705
TF TF:M00074 Factor: c-Ets-1(p54); motif: NNACMGGAWRTNN 0.0221839869995472 3484 79 27 0.341772151898734 0.00774971297359357
TF TF:M01972 Factor: EGR-1; motif: TGCGTGGGCGK 0.0230385559160477 5360 57 28 0.491228070175439 0.00522388059701493
TF TF:M03852_1 Factor: SREBP-2; motif: NTCACCYNNNN; match class: 1 0.0230385559160477 2246 7 5 0.714285714285714 0.00222617987533393
TF TF:M11811 Factor: PPARdelta; motif: NRRGGTCGYGACCYYN 0.0230385559160477 403 17 4 0.235294117647059 0.00992555831265509
TF TF:M00287_1 Factor: NF-Y; motif: NNNRRCCAATSRGNNN; match class: 1 0.0230385559160477 184 15 3 0.2 0.016304347826087
TF TF:M11765_1 Factor: TR2; motif: NRGGTCRYGACCYN; match class: 1 0.0237134606995591 1431 6 4 0.666666666666667 0.00279524807826695
TF TF:M05444_1 Factor: CPBP; motif: NGGGCGG; match class: 1 0.0237134606995591 3313 36 15 0.416666666666667 0.00452761847268337
TF TF:M05361_1 Factor: Sp6; motif: WGGGCGG; match class: 1 0.0237134606995591 3313 36 15 0.416666666666667 0.00452761847268337
TF TF:M08232_1 Factor: Elk-1:TEF; motif: RCCGGAAGTTACGTAAN; match class: 1 0.0237134606995591 1294 43 10 0.232558139534884 0.00772797527047913
TF TF:M05332_1 Factor: Sp2; motif: WGGGCGG; match class: 1 0.0237134606995591 3313 36 15 0.416666666666667 0.00452761847268337
TF TF:M11288_1 Factor: ATF-3; motif: GATGAYGTCATN; match class: 1 0.0237134606995591 1624 9 5 0.555555555555556 0.00307881773399015
TF TF:M07432 Factor: Sox-2; motif: NNNNNAACAAWGN 0.0239271554436489 1541 72 15 0.208333333333333 0.00973393900064893
TF TF:M01104 Factor: MOVO-B; motif: GNGGGGG 0.0244598394174853 10261 53 40 0.754716981132076 0.00389825553065003
TF TF:M11289_1 Factor: ATF-3; motif: NRTGACGTCAYN; match class: 1 0.0245471438452946 1661 9 5 0.555555555555556 0.00301023479831427
TF TF:M03896 Factor: EGR1; motif: NACGCCCACGCANW 0.0251445158110479 6129 42 24 0.571428571428571 0.00391581008321096
TF TF:M11866 Factor: Pax-3; motif: NNRATTAGTCACGSTN 0.0261125662975544 84 83 4 0.0481927710843374 0.0476190476190476
TF TF:M08457_1 Factor: ER71:SREBP-2; motif: NTSACGTGACGGAARY; match class: 1 0.0268201269371504 5591 43 23 0.534883720930233 0.00411375424789841
TF TF:M02017_1 Factor: HSF1; motif: GAANNTTCTRGNAN; match class: 1 0.0271060541259047 543 51 7 0.137254901960784 0.0128913443830571
TF TF:M11533 Factor: E2F-1; motif: NTTTTGGCGCCAWWWN 0.0271060541259047 13105 63 54 0.857142857142857 0.00412056466997329
TF TF:M08917 Factor: GABP-ALPHA; motif: RCCGGAARTNN 0.0275665179111346 2702 77 22 0.285714285714286 0.00814211695040711
TF TF:M07259_1 Factor: HSF1; motif: TCYAGAANNTTC; match class: 1 0.0288536416062673 732 39 7 0.179487179487179 0.00956284153005465
TF TF:M02106_1 Factor: NF-YA; motif: CRGCCAATCAGNRN; match class: 1 0.0293650433847307 217 15 3 0.2 0.0138248847926267
TF TF:M01873 Factor: Egr-1; motif: GCGGGGGCGG 0.0293650433847307 6738 7 7 1 0.0010388839418225
TF TF:M11430_1 Factor: PEA3; motif: NACCGGAAGTN; match class: 1 0.0293650433847307 4902 81 34 0.419753086419753 0.0069359445124439
TF TF:M00179_1 Factor: ATF2; motif: VGTGACGTMACN; match class: 1 0.0293827148541733 1778 9 5 0.555555555555556 0.00281214848143982
TF TF:M02023 Factor: MAZ; motif: NKGGGAGGGGRGGR 0.0297636229751562 7134 46 28 0.608695652173913 0.00392486683487525
TF TF:M11057_1 Factor: Hey1; motif: NGCACGTGYN; match class: 1 0.0303786501250826 306 44 5 0.113636363636364 0.0163398692810458
TF TF:M00243 Factor: Egr-1; motif: WTGCGTGGGCGK 0.0306397285132817 5356 40 21 0.525 0.00392083644510829
TF TF:M02053 Factor: ELF1; motif: NCCGGAARTN 0.0306397285132817 6033 78 38 0.487179487179487 0.0062986905353887
TF TF:M11230 Factor: CREBL1; motif: YGCCACGTCAYC 0.0319239068943555 56 59 3 0.0508474576271186 0.0535714285714286
TF TF:M01035 Factor: YY1; motif: NYNKCCATNTT 0.0319239068943555 5924 30 18 0.6 0.00303848750844024
TF TF:M11391 Factor: Erg; motif: NACCGGATATCCGGTN 0.0319468515765 10082 34 27 0.794117647058823 0.0026780400714144
TF TF:M03924_1 Factor: YY1; motif: NNCGCCATTNN; match class: 1 0.0319468515765 3700 41 17 0.414634146341463 0.00459459459459459
TF TF:M00245 Factor: Egr-3; motif: NTGCGTGGGCGK 0.0322074623142901 7313 60 35 0.583333333333333 0.00478599753862984
TF TF:M04681_1 Factor: JunD; motif: RTGACGTCA; match class: 1 0.0327926439875632 1726 3 3 1 0.00173812282734647
TF TF:M01165_1 Factor: Elk-1; motif: RACCGGAAGTR; match class: 1 0.0335498024564236 2185 44 13 0.295454545454545 0.00594965675057208
TF TF:M02074 Factor: GABPalpha; motif: RCCGGAWRYN 0.0335498024564236 4607 77 31 0.402597402597403 0.00672889081831995
TF TF:M00147 Factor: HSF2; motif: NGAANNWTCK 0.0335538328388065 5830 26 16 0.615384615384615 0.00274442538593482
TF TF:M03805_1 Factor: YB-1; motif: CCAMTCNGMR; match class: 1 0.0335538328388065 3680 38 16 0.421052631578947 0.00434782608695652
TF TF:M01861_1 Factor: ATF-1; motif: TNACGTCAN; match class: 1 0.0348246304138797 1896 9 5 0.555555555555556 0.00263713080168776
TF TF:M02064 Factor: c-ets-2; motif: ACCGGAWRTN 0.035387308141469 10939 79 58 0.734177215189873 0.00530212999360088
TF TF:M00793 Factor: YY1; motif: GCCATNTTN 0.03662736345791 5186 19 12 0.631578947368421 0.00231392209795604
TF TF:M00514_1 Factor: ATF4; motif: CVTGACGYMABG; match class: 1 0.03662736345791 1333 62 12 0.193548387096774 0.00900225056264066
TF TF:M08779 Factor: PXR; motif: AGTTCANNSAGTTC 0.0369651703272728 3913 30 14 0.466666666666667 0.0035778175313059
TF TF:M00246 Factor: Egr-2; motif: NTGCGTRGGCGK 0.0369651703272728 6212 43 24 0.558139534883721 0.00386349001931745
TF TF:M11271 Factor: JunD; motif: NRTGACGCAYN 0.0369651703272728 7009 39 24 0.615384615384615 0.003424168925667
TF TF:M07234 Factor: YY1; motif: CAARATGGCNGC 0.0369651703272728 6045 30 18 0.6 0.00297766749379653
TF TF:M08877_1 Factor: EGR3; motif: NCMCRCCCACTNMN; match class: 1 0.0370134841738934 1397 68 13 0.191176470588235 0.00930565497494631
TF TF:M11290_1 Factor: ATF-3; motif: NATGATGTCATN; match class: 1 0.0370134841738934 1872 3 3 1 0.0016025641025641
TF TF:M00513_1 Factor: ATF3; motif: CBCTGACGTCANCS; match class: 1 0.0370134841738934 3374 4 4 1 0.001185536455246
TF TF:M08941_1 Factor: C-JUN:FRA-2; motif: NRTGACGTMAT; match class: 1 0.0370134841738934 3353 4 4 1 0.00119296152699075
TF TF:M07323 Factor: IRF-4; motif: KRAAMNGAAANYN 0.0370134841738934 938 10 4 0.4 0.00426439232409382
TF TF:M11224 Factor: CREM; motif: NRTGATGTCAYN 0.0370216792612131 3382 4 4 1 0.00118273211117682
TF TF:M10104 Factor: YY1; motif: CAARATGGCGGC 0.0371835013124793 6071 30 18 0.6 0.00296491517048262
TF TF:M08800 Factor: ARNT; motif: YRCGTGNN 0.0373777394664543 914 55 9 0.163636363636364 0.00984682713347921
TF TF:M11745_1 Factor: COUP-TF1; motif: RAGGTCANTGACCTY; match class: 1 0.0373913637725814 1954 44 12 0.272727272727273 0.00614124872057318
TF TF:M02065_1 Factor: ER81; motif: RCCGGAARYN; match class: 1 0.0373913637725814 6749 79 41 0.518987341772152 0.00607497407023263
TF TF:M11313_1 Factor: CREBPA; motif: NRTGACGTMANN; match class: 1 0.0407527425695343 2025 9 5 0.555555555555556 0.00246913580246914
TF TF:M04020_1 Factor: IRF8; motif: NCGAAACCGAAACT; match class: 1 0.041528742596463 45 87 3 0.0344827586206897 0.0666666666666667
TF TF:M00338_1 Factor: ATF; motif: NTGACGTCANYS; match class: 1 0.0417825081579249 1122 9 4 0.444444444444444 0.0035650623885918
TF TF:M03971_1 Factor: ELK1; motif: NACTTCCGSCGGAAGYN; match class: 1 0.0421720325287892 7157 43 26 0.604651162790698 0.00363280704205673
TF TF:M07459_1 Factor: HSF1; motif: GAANNTTCTNGN; match class: 1 0.0421720325287892 413 76 7 0.0921052631578947 0.0169491525423729
TF TF:M11763_1 Factor: TR2; motif: RRGGTCRYGACCYY; match class: 1 0.0424554517696545 241 17 3 0.176470588235294 0.012448132780083
TF TF:M09816_1 Factor: NFYA; motif: RRCCAATCAGN; match class: 1 0.0434484161166156 278 15 3 0.2 0.0107913669064748
TF TF:M11815_1 Factor: T3R-beta; motif: NNRGGTCRTGACCYNN; match class: 1 0.043888993536747 1675 59 13 0.220338983050847 0.00776119402985075
TF TF:M09905 Factor: SAP-1; motif: NNCCGGAAGTGN 0.043888993536747 8273 44 29 0.659090909090909 0.00350537894355131
TF TF:M11222 Factor: CREB1; motif: NRTGAYGTCAYN 0.0468301918552934 3688 4 4 1 0.00108459869848156
TF TF:M07397 Factor: ZBP89; motif: CCCCKCCCCCNN 0.0484576852046217 7143 83 44 0.530120481927711 0.00615987680246395
TF TF:M08913 Factor: FLI-1; motif: NAYTTCCGGT 0.0484576852046217 8322 44 29 0.659090909090909 0.00348473924537371
TF TF:M04490_1 Factor: RXRA; motif: RRGGTCATGACCYY; match class: 1 0.0486622538066625 3535 27 12 0.444444444444444 0.00339462517680339
TF TF:M07600_1 Factor: C-Fos; motif: NNTGACTCAN; match class: 1 0.0488199833851664 279 85 6 0.0705882352941176 0.021505376344086
TF TF:M02066 Factor: PEA3; motif: RCCGGAAGYN 0.0488874638865428 7045 44 26 0.590909090909091 0.00369056068133428
TF TF:M11601_1 Factor: TCF-1; motif: ACATCGRGRCGCTGW; match class: 1 0.049106460864662 11053 81 59 0.728395061728395 0.00533791730751832
TF TF:M04802_1 Factor: c-Fos; motif: ACTCACCA; match class: 1 0.049106460864662 1481 37 9 0.243243243243243 0.00607697501688049
TF TF:M00641_1 Factor: HSF; motif: TTCCMGARGYTTC; match class: 1 0.049106460864662 387 25 4 0.16 0.0103359173126615
TF TF:M11781 Factor: RXR-beta; motif: RRGGTCGTGACCYY 0.0493220025515347 261 17 3 0.176470588235294 0.0114942528735632
WP WP:WP183 Proteasome Degradation 1.29334191370337e-05 64 6 4 0.666666666666667 0.0625
WP WP:WP2328 Allograft Rejection 0.000135119017445466 88 18 5 0.277777777777778 0.0568181818181818
WP WP:WP4217 Ebola Virus Pathway on Host 0.000619510479841862 130 18 5 0.277777777777778 0.0384615384615385
WP WP:WP262 EBV LMP1 signaling 0.000703349627065541 24 49 4 0.0816326530612245 0.166666666666667
WP WP:WP2884 NRF2 pathway 0.00562280735835802 145 15 4 0.266666666666667 0.0275862068965517
WP WP:WP231 TNF alpha Signaling Pathway 0.00771002980887518 94 49 5 0.102040816326531 0.0531914893617021
WP WP:WP2359 Parkin-Ubiquitin Proteasomal System pathway 0.00771002980887518 70 15 3 0.2 0.0428571428571429
WP WP:WP530 Cytokines and Inflammatory Response 0.0124808103479924 26 49 3 0.0612244897959184 0.115384615384615
WP WP:WP382 MAPK Signaling Pathway 0.0187068574609363 249 49 7 0.142857142857143 0.0281124497991968
WP WP:WP2036 TNF related weak inducer of apoptosis (TWEAK) Signaling Pathway 0.035481594188142 42 49 3 0.0612244897959184 0.0714285714285714
WP WP:WP2882 Nuclear Receptors Meta-Pathway 0.0398523694076871 321 15 4 0.266666666666667 0.0124610591900312

pB12 transcription factor target enrichment of top program genes

TF enrichment of pB12
TFs corrosponding to activation of pB12. (Left) pearson correlation of TF expression and gene expression program activatity in B cells, (right) negative log p-value for enrichment of TF binding sites among top uniqueness weighted genes for the gene program. Blue bars indicate significant TFs meeting the following criteria: FDR<0.1, overlap > 2, Corr. R > 0, permutation based p-value < 0.05.