pS17 program activity among Stromal cells

Activation of pS17
pS17 gene program activation in Stromal cells.
Gene program activation of pS17 by different cell subtypes
pS17 gene program activation among cells of different subtypes (Stromal cells).

pS17 top program genes

Top genes of pS17 program
Bar plots showing the top genes for each gene program, ranked by (left) unique weights, (right) raw weights.

pS17 gene-set enrichment of top program genes (using g-profiler)

GSEA wth gene profiler of pS17
pS17 gene-set enrichment summary using g-profiler webtool.
Source termID Name Padj Tsize Qsize Overlap Precision Recall
GO:BP GO:0007166 cell surface receptor signaling pathway 2.33023843188109e-10 3210 89 47 0.528089887640449 0.0146417445482866
GO:BP GO:2000145 regulation of cell motility 1.06466531784202e-09 1061 89 27 0.303370786516854 0.0254476908576814
GO:BP GO:0030334 regulation of cell migration 1.28488153906244e-09 999 89 26 0.292134831460674 0.026026026026026
GO:BP GO:0040012 regulation of locomotion 1.3569916315615e-09 1104 89 27 0.303370786516854 0.0244565217391304
GO:BP GO:0051270 regulation of cellular component movement 2.3474544505639e-09 1141 89 27 0.303370786516854 0.0236634531113059
GO:BP GO:0009887 animal organ morphogenesis 3.2448790756697e-09 1073 89 26 0.292134831460674 0.0242311276794035
GO:BP GO:0030278 regulation of ossification 5.43715670928426e-09 115 89 11 0.123595505617978 0.0956521739130435
GO:BP GO:0051241 negative regulation of multicellular organismal process 1.38901232616423e-08 1160 89 26 0.292134831460674 0.0224137931034483
GO:BP GO:0071363 cellular response to growth factor stimulus 1.64963872001585e-08 731 89 21 0.235955056179775 0.0287277701778386
GO:BP GO:0009888 tissue development 2.2911177152699e-08 2107 106 38 0.358490566037736 0.0180351210251542
GO:BP GO:0072006 nephron development 2.2911177152699e-08 142 140 13 0.0928571428571429 0.0915492957746479
GO:BP GO:0007167 enzyme linked receptor protein signaling pathway 2.2911177152699e-08 1103 89 25 0.280898876404494 0.0226654578422484
GO:BP GO:0070848 response to growth factor 2.2911177152699e-08 759 89 21 0.235955056179775 0.0276679841897233
GO:BP GO:0071495 cellular response to endogenous stimulus 2.3215570491629e-08 1422 89 28 0.314606741573034 0.019690576652602
GO:BP GO:0016477 cell migration 2.4858227438245e-08 1649 89 30 0.337078651685393 0.0181928441479685
GO:BP GO:0040011 locomotion 2.4858227438245e-08 2028 79 31 0.392405063291139 0.0152859960552268
GO:BP GO:0009719 response to endogenous stimulus 3.73049465685911e-08 1683 89 30 0.337078651685393 0.017825311942959
GO:BP GO:0051093 negative regulation of developmental process 4.32280167467146e-08 977 89 23 0.258426966292135 0.0235414534288639
GO:BP GO:0051674 localization of cell 4.33707544412253e-08 1828 79 29 0.367088607594937 0.0158643326039387
GO:BP GO:0048870 cell motility 4.33707544412253e-08 1828 79 29 0.367088607594937 0.0158643326039387
GO:BP GO:0010033 response to organic substance 4.71562095030363e-08 3412 89 43 0.48314606741573 0.0126025791324736
GO:BP GO:2000147 positive regulation of cell motility 7.88124355069153e-08 591 89 18 0.202247191011236 0.0304568527918782
GO:BP GO:0048762 mesenchymal cell differentiation 7.88124355069153e-08 234 99 13 0.131313131313131 0.0555555555555556
GO:BP GO:0009653 anatomical structure morphogenesis 8.16746464665586e-08 2797 107 43 0.401869158878505 0.0153736145870576
GO:BP GO:0071310 cellular response to organic substance 8.16746464665586e-08 2776 89 38 0.426966292134831 0.0136887608069164
GO:BP GO:0009966 regulation of signal transduction 9.04164415168563e-08 3165 104 45 0.432692307692308 0.014218009478673
GO:BP GO:0060485 mesenchyme development 9.04164415168563e-08 291 99 14 0.141414141414141 0.0481099656357388
GO:BP GO:0040017 positive regulation of locomotion 9.04164415168563e-08 606 89 18 0.202247191011236 0.0297029702970297
GO:BP GO:0051272 positive regulation of cellular component movement 9.04164415168563e-08 604 89 18 0.202247191011236 0.0298013245033113
GO:BP GO:0042221 response to chemical 9.04164415168563e-08 4781 89 51 0.573033707865168 0.0106672244300356
GO:BP GO:0070887 cellular response to chemical stimulus 1.07973236685655e-07 3393 89 42 0.471910112359551 0.0123784261715296
GO:BP GO:0030154 cell differentiation 1.34348370993977e-07 4350 89 48 0.539325842696629 0.0110344827586207
GO:BP GO:0045667 regulation of osteoblast differentiation 1.34348370993977e-07 135 89 10 0.112359550561798 0.0740740740740741
GO:BP GO:0042692 muscle cell differentiation 1.40760358876888e-07 390 79 14 0.177215189873418 0.0358974358974359
GO:BP GO:0051239 regulation of multicellular organismal process 1.40760358876888e-07 2861 89 38 0.426966292134831 0.0132820692065711
GO:BP GO:0007165 signal transduction 1.44326413311639e-07 6309 95 62 0.652631578947368 0.00982723093992709
GO:BP GO:0050793 regulation of developmental process 1.58530360083778e-07 2605 89 36 0.404494382022472 0.0138195777351248
GO:BP GO:0001503 ossification 1.69976356240767e-07 417 89 15 0.168539325842697 0.0359712230215827
GO:BP GO:0003197 endocardial cushion development 1.75514712971323e-07 44 89 7 0.0786516853932584 0.159090909090909
GO:BP GO:0061061 muscle structure development 1.82621638121265e-07 645 79 17 0.215189873417722 0.0263565891472868
GO:BP GO:0030335 positive regulation of cell migration 1.82621638121265e-07 567 89 17 0.191011235955056 0.0299823633156966
GO:BP GO:0010646 regulation of cell communication 1.83123577483893e-07 3543 94 44 0.468085106382979 0.0124188540784646
GO:BP GO:0048869 cellular developmental process 1.89177759104697e-07 4428 89 48 0.539325842696629 0.010840108401084
GO:BP GO:0072080 nephron tubule development 2.0006271836228e-07 92 140 10 0.0714285714285714 0.108695652173913
GO:BP GO:0001501 skeletal system development 2.26558596952187e-07 504 89 16 0.179775280898876 0.0317460317460317
GO:BP GO:0051094 positive regulation of developmental process 2.26558596952187e-07 1341 101 27 0.267326732673267 0.0201342281879195
GO:BP GO:0048513 animal organ development 2.26558596952187e-07 3672 89 43 0.48314606741573 0.0117102396514161
GO:BP GO:0023051 regulation of signaling 2.26558596952187e-07 3578 94 44 0.468085106382979 0.0122973728339855
GO:BP GO:0060562 epithelial tube morphogenesis 2.37083623059913e-07 329 99 14 0.141414141414141 0.0425531914893617
GO:BP GO:0061326 renal tubule development 2.41511753553019e-07 95 140 10 0.0714285714285714 0.105263157894737
GO:BP GO:0008284 positive regulation of cell population proliferation 2.41511753553019e-07 982 101 23 0.227722772277228 0.0234215885947047
GO:BP GO:0007169 transmembrane receptor protein tyrosine kinase signaling pathway 2.41511753553019e-07 760 79 18 0.227848101265823 0.0236842105263158
GO:BP GO:0032879 regulation of localization 2.41511753553019e-07 2872 110 43 0.390909090909091 0.0149721448467967
GO:BP GO:0045595 regulation of cell differentiation 2.65854729705969e-07 1679 89 28 0.314606741573034 0.0166765932102442
GO:BP GO:0009967 positive regulation of signal transduction 2.71895899761221e-07 1598 82 26 0.317073170731707 0.016270337922403
GO:BP GO:0045778 positive regulation of ossification 2.71895899761221e-07 49 89 7 0.0786516853932584 0.142857142857143
GO:BP GO:0061448 connective tissue development 2.96673315855489e-07 256 89 12 0.134831460674157 0.046875
GO:BP GO:0048729 tissue morphogenesis 3.92970984788494e-07 667 103 19 0.184466019417476 0.0284857571214393
GO:BP GO:0072028 nephron morphogenesis 3.99373913803845e-07 75 140 9 0.0642857142857143 0.12
GO:BP GO:0045596 negative regulation of cell differentiation 4.08639890071622e-07 697 89 18 0.202247191011236 0.0258249641319943
GO:BP GO:0010647 positive regulation of cell communication 4.95387071521483e-07 1777 82 27 0.329268292682927 0.0151941474395048
GO:BP GO:0023056 positive regulation of signaling 5.17734047432222e-07 1782 82 27 0.329268292682927 0.0151515151515152
GO:BP GO:0072073 kidney epithelium development 5.51704982133035e-07 137 140 11 0.0785714285714286 0.0802919708029197
GO:BP GO:0072001 renal system development 6.05936828591662e-07 302 99 13 0.131313131313131 0.043046357615894
GO:BP GO:0023052 signaling 6.20608548248954e-07 6810 89 60 0.674157303370786 0.00881057268722467
GO:BP GO:0001658 branching involved in ureteric bud morphogenesis 6.24022685445628e-07 56 140 8 0.0571428571428571 0.142857142857143
GO:BP GO:0006935 chemotaxis 6.50507870566748e-07 653 67 15 0.223880597014925 0.0229709035222052
GO:BP GO:0032502 developmental process 6.50507870566748e-07 6628 89 59 0.662921348314607 0.00890162945081473
GO:BP GO:0035295 tube development 6.50507870566748e-07 1146 79 21 0.265822784810127 0.0183246073298429
GO:BP GO:0007154 cell communication 6.50507870566748e-07 6829 89 60 0.674157303370786 0.00878605945233563
GO:BP GO:0006928 movement of cell or subcellular component 6.50507870566748e-07 2311 79 30 0.379746835443038 0.0129813933362181
GO:BP GO:0014032 neural crest cell development 6.53282855773579e-07 80 99 8 0.0808080808080808 0.1
GO:BP GO:0042330 taxis 6.53282855773579e-07 656 67 15 0.223880597014925 0.0228658536585366
GO:BP GO:0072009 nephron epithelium development 6.87710118132006e-07 110 140 10 0.0714285714285714 0.0909090909090909
GO:BP GO:0048856 anatomical structure development 8.017288859598e-07 6106 89 56 0.629213483146067 0.00917130691123485
GO:BP GO:0014031 mesenchymal cell development 9.14930245285376e-07 84 99 8 0.0808080808080808 0.0952380952380952
GO:BP GO:0048864 stem cell development 9.14930245285376e-07 84 99 8 0.0808080808080808 0.0952380952380952
GO:BP GO:0048583 regulation of response to stimulus 1.13004328402834e-06 4278 94 47 0.5 0.0109864422627396
GO:BP GO:0060675 ureteric bud morphogenesis 1.19351187119298e-06 62 140 8 0.0571428571428571 0.129032258064516
GO:BP GO:0048754 branching morphogenesis of an epithelial tube 1.20206461694465e-06 151 140 11 0.0785714285714286 0.0728476821192053
GO:BP GO:0072171 mesonephric tubule morphogenesis 1.32473465609729e-06 63 140 8 0.0571428571428571 0.126984126984127
GO:BP GO:0014033 neural crest cell differentiation 1.48715989706036e-06 90 99 8 0.0808080808080808 0.0888888888888889
GO:BP GO:0032501 multicellular organismal process 1.53254093076749e-06 7946 114 79 0.692982456140351 0.00994210923735213
GO:BP GO:0030501 positive regulation of bone mineralization 1.53990612721478e-06 39 89 6 0.0674157303370786 0.153846153846154
GO:BP GO:0001655 urogenital system development 1.66918724694077e-06 337 99 13 0.131313131313131 0.0385756676557863
GO:BP GO:0001657 ureteric bud development 1.67157937654456e-06 92 140 9 0.0642857142857143 0.0978260869565217
GO:BP GO:0060993 kidney morphogenesis 1.67157937654456e-06 92 140 9 0.0642857142857143 0.0978260869565217
GO:BP GO:0022008 neurogenesis 1.67157937654456e-06 1675 128 33 0.2578125 0.0197014925373134
GO:BP GO:0072164 mesonephric tubule development 1.77138185816624e-06 93 140 9 0.0642857142857143 0.0967741935483871
GO:BP GO:0051216 cartilage development 1.77138185816624e-06 196 89 10 0.112359550561798 0.0510204081632653
GO:BP GO:0072163 mesonephric epithelium development 1.77138185816624e-06 93 140 9 0.0642857142857143 0.0967741935483871
GO:BP GO:0072111 cell proliferation involved in kidney development 2.00187011955058e-06 21 89 5 0.0561797752808989 0.238095238095238
GO:BP GO:0072359 circulatory system development 2.00187011955058e-06 1194 89 22 0.247191011235955 0.0184254606365159
GO:BP GO:0045669 positive regulation of osteoblast differentiation 2.05477863330432e-06 70 89 7 0.0786516853932584 0.1
GO:BP GO:0071675 regulation of mononuclear cell migration 2.20155990622724e-06 113 56 7 0.125 0.0619469026548673
GO:BP GO:0002009 morphogenesis of an epithelium 2.34930544799256e-06 560 99 16 0.161616161616162 0.0285714285714286
GO:BP GO:0001823 mesonephros development 2.39464404160429e-06 97 140 9 0.0642857142857143 0.0927835051546392
GO:BP GO:0001822 kidney development 2.51007029045886e-06 293 140 14 0.1 0.0477815699658703
GO:BP GO:0042127 regulation of cell population proliferation 2.6267907435857e-06 1774 101 29 0.287128712871287 0.0163472378804961
GO:BP GO:0035270 endocrine system development 2.70095549560442e-06 130 76 8 0.105263157894737 0.0615384615384615
GO:BP GO:0072078 nephron tubule morphogenesis 2.77092281245695e-06 71 140 8 0.0571428571428571 0.112676056338028
GO:BP GO:0007275 multicellular organism development 2.79341718478692e-06 5613 89 52 0.584269662921348 0.00926420808836629
GO:BP GO:0030500 regulation of bone mineralization 2.79341718478692e-06 74 89 7 0.0786516853932584 0.0945945945945946
GO:BP GO:0035051 cardiocyte differentiation 2.823832828454e-06 157 89 9 0.101123595505618 0.0573248407643312
GO:BP GO:0003156 regulation of animal organ formation 2.84868161765062e-06 29 140 6 0.0428571428571429 0.206896551724138
GO:BP GO:0072088 nephron epithelium morphogenesis 3.29282351285631e-06 73 140 8 0.0571428571428571 0.10958904109589
GO:BP GO:0042327 positive regulation of phosphorylation 3.31305029362998e-06 927 89 19 0.213483146067416 0.0204962243797195
GO:BP GO:0051716 cellular response to stimulus 3.35493167904861e-06 7781 89 63 0.707865168539326 0.00809664567536306
GO:BP GO:0070169 positive regulation of biomineral tissue development 3.78468038469808e-06 47 89 6 0.0674157303370786 0.127659574468085
GO:BP GO:0001934 positive regulation of protein phosphorylation 3.84598081175381e-06 840 89 18 0.202247191011236 0.0214285714285714
GO:BP GO:0061333 renal tubule morphogenesis 3.89576288109976e-06 75 140 8 0.0571428571428571 0.106666666666667
GO:BP GO:0071674 mononuclear cell migration 4.04839440487207e-06 191 56 8 0.142857142857143 0.0418848167539267
GO:BP GO:0060173 limb development 4.04839440487207e-06 176 140 11 0.0785714285714286 0.0625
GO:BP GO:0110151 positive regulation of biomineralization 4.04839440487207e-06 48 89 6 0.0674157303370786 0.125
GO:BP GO:0065008 regulation of biological quality 4.04839440487207e-06 4131 113 51 0.451327433628319 0.0123456790123457
GO:BP GO:0048736 appendage development 4.04839440487207e-06 176 140 11 0.0785714285714286 0.0625
GO:BP GO:0048585 negative regulation of response to stimulus 4.51841558889903e-06 1733 89 26 0.292134831460674 0.015002885170225
GO:BP GO:0048738 cardiac muscle tissue development 4.78380233977571e-06 224 89 10 0.112359550561798 0.0446428571428571
GO:BP GO:0061138 morphogenesis of a branching epithelium 5.19031732106917e-06 181 140 11 0.0785714285714286 0.0607734806629834
GO:BP GO:0048731 system development 6.19838276865988e-06 5052 89 48 0.539325842696629 0.00950118764845606
GO:BP GO:0001649 osteoblast differentiation 6.46415821305508e-06 232 89 10 0.112359550561798 0.0431034482758621
GO:BP GO:0031128 developmental induction 7.97871450012399e-06 35 140 6 0.0428571428571429 0.171428571428571
GO:BP GO:0110110 positive regulation of animal organ morphogenesis 7.97871450012399e-06 35 140 6 0.0428571428571429 0.171428571428571
GO:BP GO:0007399 nervous system development 7.97871450012399e-06 2449 130 40 0.307692307692308 0.0163331972233565
GO:BP GO:0051240 positive regulation of multicellular organismal process 8.4961729854733e-06 1455 101 25 0.247524752475248 0.0171821305841924
GO:BP GO:0042475 odontogenesis of dentin-containing tooth 8.82560949359544e-06 90 89 7 0.0786516853932584 0.0777777777777778
GO:BP GO:0060429 epithelium development 8.98850121131642e-06 1325 89 22 0.247191011235955 0.0166037735849057
GO:BP GO:0045937 positive regulation of phosphate metabolic process 9.02948232433793e-06 1001 89 19 0.213483146067416 0.018981018981019
GO:BP GO:0010562 positive regulation of phosphorus metabolic process 9.02948232433793e-06 1001 89 19 0.213483146067416 0.018981018981019
GO:BP GO:0001656 metanephros development 9.72156164283074e-06 86 140 8 0.0571428571428571 0.0930232558139535
GO:BP GO:0045597 positive regulation of cell differentiation 9.72156164283074e-06 879 101 19 0.188118811881188 0.0216154721274175
GO:BP GO:0001763 morphogenesis of a branching structure 9.83571859258665e-06 195 140 11 0.0785714285714286 0.0564102564102564
GO:BP GO:0048523 negative regulation of cellular process 9.83571859258665e-06 5139 89 48 0.539325842696629 0.00934033858727379
GO:BP GO:0030326 embryonic limb morphogenesis 1.00147708307389e-05 119 140 9 0.0642857142857143 0.0756302521008403
GO:BP GO:0035113 embryonic appendage morphogenesis 1.00147708307389e-05 119 140 9 0.0642857142857143 0.0756302521008403
GO:BP GO:0032101 regulation of response to external stimulus 1.00147708307389e-05 1051 70 17 0.242857142857143 0.0161750713606089
GO:BP GO:0070167 regulation of biomineral tissue development 1.01705676798992e-05 93 89 7 0.0786516853932584 0.0752688172043011
GO:BP GO:0048598 embryonic morphogenesis 1.0871360222582e-05 595 120 17 0.141666666666667 0.0285714285714286
GO:BP GO:0048646 anatomical structure formation involved in morphogenesis 1.12476662296137e-05 1202 99 22 0.222222222222222 0.0183028286189684
GO:BP GO:0003007 heart morphogenesis 1.14704442839609e-05 251 89 10 0.112359550561798 0.0398406374501992
GO:BP GO:0110149 regulation of biomineralization 1.14704442839609e-05 95 89 7 0.0786516853932584 0.0736842105263158
GO:BP GO:0050920 regulation of chemotaxis 1.18017759762459e-05 226 56 8 0.142857142857143 0.0353982300884956
GO:BP GO:0008283 cell population proliferation 1.19944896484224e-05 2054 101 30 0.297029702970297 0.0146056475170399
GO:BP GO:0030182 neuron differentiation 1.23988527279038e-05 1412 128 28 0.21875 0.0198300283286119
GO:BP GO:0009968 negative regulation of signal transduction 1.28433407803541e-05 1364 89 22 0.247191011235955 0.0161290322580645
GO:BP GO:0060537 muscle tissue development 1.28433407803541e-05 399 45 9 0.2 0.0225563909774436
GO:BP GO:0090092 regulation of transmembrane receptor protein serine/threonine kinase signaling pathway 1.3663062818724e-05 257 89 10 0.112359550561798 0.0389105058365759
GO:BP GO:0055007 cardiac muscle cell differentiation 1.41363178445805e-05 124 71 7 0.0985915492957746 0.0564516129032258
GO:BP GO:1901700 response to oxygen-containing compound 1.4851597086951e-05 1739 89 25 0.280898876404494 0.0143760782058654
GO:BP GO:0060393 regulation of pathway-restricted SMAD protein phosphorylation 1.4851597086951e-05 62 89 6 0.0674157303370786 0.0967741935483871
GO:BP GO:0048008 platelet-derived growth factor receptor signaling pathway 1.62897596055218e-05 59 51 5 0.0980392156862745 0.0847457627118644
GO:BP GO:0048584 positive regulation of response to stimulus 1.64208024114926e-05 2344 82 28 0.341463414634146 0.0119453924914676
GO:BP GO:0048699 generation of neurons 1.64208024114926e-05 1559 74 21 0.283783783783784 0.013470173187941
GO:BP GO:0002062 chondrocyte differentiation 1.69023911859845e-05 108 84 7 0.0833333333333333 0.0648148148148148
GO:BP GO:0060322 head development 1.96298112096721e-05 798 128 20 0.15625 0.025062656641604
GO:BP GO:0007507 heart development 1.99519111253851e-05 578 89 14 0.157303370786517 0.0242214532871972
GO:BP GO:0007417 central nervous system development 2.02445565426225e-05 1032 128 23 0.1796875 0.0222868217054264
GO:BP GO:0060389 pathway-restricted SMAD protein phosphorylation 2.05040754923372e-05 66 89 6 0.0674157303370786 0.0909090909090909
GO:BP GO:0045165 cell fate commitment 2.27542495048592e-05 267 71 9 0.126760563380282 0.0337078651685393
GO:BP GO:2000026 regulation of multicellular organismal development 2.27542495048592e-05 1447 101 24 0.237623762376238 0.0165860400829302
GO:BP GO:0001837 epithelial to mesenchymal transition 2.31020832932501e-05 156 89 8 0.0898876404494382 0.0512820512820513
GO:BP GO:0002065 columnar/cuboidal epithelial cell differentiation 3.05323187271422e-05 89 71 6 0.0845070422535211 0.0674157303370786
GO:BP GO:1905330 regulation of morphogenesis of an epithelium 3.06345462618744e-05 64 99 6 0.0606060606060606 0.09375
GO:BP GO:0007420 brain development 3.25489778183286e-05 754 128 19 0.1484375 0.0251989389920424
GO:BP GO:1905332 positive regulation of morphogenesis of an epithelium 3.27151933893694e-05 36 99 5 0.0505050505050505 0.138888888888889
GO:BP GO:0048863 stem cell differentiation 3.30889044486452e-05 258 99 10 0.101010101010101 0.0387596899224806
GO:BP GO:0035108 limb morphogenesis 3.30889044486452e-05 141 140 9 0.0642857142857143 0.0638297872340425
GO:BP GO:2000725 regulation of cardiac muscle cell differentiation 3.30889044486452e-05 22 71 4 0.0563380281690141 0.181818181818182
GO:BP GO:0035107 appendage morphogenesis 3.30889044486452e-05 141 140 9 0.0642857142857143 0.0638297872340425
GO:BP GO:1901701 cellular response to oxygen-containing compound 3.41181879734991e-05 1227 89 20 0.224719101123595 0.0162999185004075
GO:BP GO:0035239 tube morphogenesis 3.4924709098662e-05 950 76 16 0.210526315789474 0.0168421052631579
GO:BP GO:0030282 bone mineralization 3.55705831890288e-05 116 89 7 0.0786516853932584 0.0603448275862069
GO:BP GO:0048705 skeletal system morphogenesis 3.59423364367286e-05 226 89 9 0.101123595505618 0.0398230088495575
GO:BP GO:0010648 negative regulation of cell communication 3.62431651231018e-05 1468 89 22 0.247191011235955 0.0149863760217984
GO:BP GO:0009798 axis specification 3.66275702310213e-05 87 76 6 0.0789473684210526 0.0689655172413793
GO:BP GO:0023057 negative regulation of signaling 3.70752663548313e-05 1471 89 22 0.247191011235955 0.0149558123725357
GO:BP GO:0002067 glandular epithelial cell differentiation 3.80059513827702e-05 52 71 5 0.0704225352112676 0.0961538461538462
GO:BP GO:2000064 regulation of cortisol biosynthetic process 4.08945526512215e-05 7 71 3 0.0422535211267606 0.428571428571429
GO:BP GO:0032344 regulation of aldosterone metabolic process 4.08945526512215e-05 7 71 3 0.0422535211267606 0.428571428571429
GO:BP GO:0032347 regulation of aldosterone biosynthetic process 4.08945526512215e-05 7 71 3 0.0422535211267606 0.428571428571429
GO:BP GO:0071772 response to BMP 4.08945526512215e-05 171 89 8 0.0898876404494382 0.0467836257309941
GO:BP GO:0071773 cellular response to BMP stimulus 4.08945526512215e-05 171 89 8 0.0898876404494382 0.0467836257309941
GO:BP GO:0045445 myoblast differentiation 4.08945526512215e-05 84 45 5 0.111111111111111 0.0595238095238095
GO:BP GO:0003206 cardiac chamber morphogenesis 4.18164045533395e-05 120 89 7 0.0786516853932584 0.0583333333333333
GO:BP GO:2001237 negative regulation of extrinsic apoptotic signaling pathway 4.20723589555279e-05 108 99 7 0.0707070707070707 0.0648148148148148
GO:BP GO:0060037 pharyngeal system development 4.23468696359605e-05 26 18 3 0.166666666666667 0.115384615384615
GO:BP GO:0048468 cell development 4.42949416979565e-05 2100 106 30 0.283018867924528 0.0142857142857143
GO:BP GO:0061005 cell differentiation involved in kidney development 4.51722851147022e-05 58 120 6 0.05 0.103448275862069
GO:BP GO:0048565 digestive tract development 4.52128176614176e-05 129 120 8 0.0666666666666667 0.062015503875969
GO:BP GO:0051153 regulation of striated muscle cell differentiation 4.54771463053122e-05 98 71 6 0.0845070422535211 0.0612244897959184
GO:BP GO:0003002 regionalization 4.62182056708008e-05 338 99 11 0.111111111111111 0.0325443786982249
GO:BP GO:0061383 trabecula morphogenesis 4.63810965357548e-05 44 89 5 0.0561797752808989 0.113636363636364
GO:BP GO:0051146 striated muscle cell differentiation 4.85673986387013e-05 289 94 10 0.106382978723404 0.0346020761245675
GO:BP GO:0014706 striated muscle tissue development 4.85673986387013e-05 380 89 11 0.123595505617978 0.0289473684210526
GO:BP GO:0007267 cell-cell signaling 4.85673986387013e-05 1722 128 30 0.234375 0.0174216027874564
GO:BP GO:2001236 regulation of extrinsic apoptotic signaling pathway 4.86998865621992e-05 159 99 8 0.0808080808080808 0.050314465408805
GO:BP GO:0031946 regulation of glucocorticoid biosynthetic process 6.01017967965221e-05 8 71 3 0.0422535211267606 0.375
GO:BP GO:0050900 leukocyte migration 6.08492444715959e-05 511 56 10 0.178571428571429 0.0195694716242661
GO:BP GO:0010862 positive regulation of pathway-restricted SMAD protein phosphorylation 6.22171444578582e-05 47 89 5 0.0561797752808989 0.106382978723404
GO:BP GO:0042476 odontogenesis 6.5454237137988e-05 130 89 7 0.0786516853932584 0.0538461538461538
GO:BP GO:1903034 regulation of response to wounding 6.66247462285106e-05 169 69 7 0.101449275362319 0.0414201183431953
GO:BP GO:0061154 endothelial tube morphogenesis 6.78668922182548e-05 20 28 3 0.107142857142857 0.15
GO:BP GO:0003159 morphogenesis of an endothelium 6.78668922182548e-05 20 28 3 0.107142857142857 0.15
GO:BP GO:0002685 regulation of leukocyte migration 6.83664411922052e-05 211 56 7 0.125 0.033175355450237
GO:BP GO:0050818 regulation of coagulation 6.83664411922052e-05 75 26 4 0.153846153846154 0.0533333333333333
GO:BP GO:0055123 digestive system development 6.83664411922052e-05 138 120 8 0.0666666666666667 0.0579710144927536
GO:BP GO:0043010 camera-type eye development 6.83664411922052e-05 331 106 11 0.10377358490566 0.0332326283987915
GO:BP GO:0031401 positive regulation of protein modification process 6.97546462791707e-05 1074 89 18 0.202247191011236 0.0167597765363128
GO:BP GO:0072012 glomerulus vasculature development 7.19010992592935e-05 25 23 3 0.130434782608696 0.12
GO:BP GO:0030193 regulation of blood coagulation 7.41164313680956e-05 68 9 3 0.333333333333333 0.0441176470588235
GO:BP GO:1900046 regulation of hemostasis 7.71074368887546e-05 69 9 3 0.333333333333333 0.0434782608695652
GO:BP GO:0061437 renal system vasculature development 7.93580534556524e-05 26 23 3 0.130434782608696 0.115384615384615
GO:BP GO:0048519 negative regulation of biological process 7.93580534556524e-05 5757 89 49 0.550561797752809 0.00851137745353483
GO:BP GO:0061440 kidney vasculature development 7.93580534556524e-05 26 23 3 0.130434782608696 0.115384615384615
GO:BP GO:0060326 cell chemotaxis 8.09549614489683e-05 310 56 8 0.142857142857143 0.0258064516129032
GO:BP GO:0032353 negative regulation of hormone biosynthetic process 8.18000395789516e-05 9 71 3 0.0422535211267606 0.333333333333333
GO:BP GO:0035733 hepatic stellate cell activation 8.18000395789516e-05 8 81 3 0.037037037037037 0.375
GO:BP GO:0050896 response to stimulus 8.49068372751345e-05 9407 89 67 0.752808988764045 0.00712235569256936
GO:BP GO:0072132 mesenchyme morphogenesis 8.54418500612093e-05 51 89 5 0.0561797752808989 0.0980392156862745
GO:BP GO:0007389 pattern specification process 8.80826072229752e-05 442 99 12 0.121212121212121 0.0271493212669683
GO:BP GO:0003272 endocardial cushion formation 9.04624120238916e-05 24 89 4 0.0449438202247191 0.166666666666667
GO:BP GO:0001838 embryonic epithelial tube formation 9.28903764038855e-05 125 99 7 0.0707070707070707 0.056
GO:BP GO:0030855 epithelial cell differentiation 0.000106463938746613 798 99 16 0.161616161616162 0.0200501253132832
GO:BP GO:0072210 metanephric nephron development 0.00010668839918756 40 120 5 0.0416666666666667 0.125
GO:BP GO:0032351 negative regulation of hormone metabolic process 0.000108694626057619 10 71 3 0.0422535211267606 0.3
GO:BP GO:0032341 aldosterone metabolic process 0.000108694626057619 10 71 3 0.0422535211267606 0.3
GO:BP GO:0072077 renal vesicle morphogenesis 0.000108694626057619 19 120 4 0.0333333333333333 0.210526315789474
GO:BP GO:0042487 regulation of odontogenesis of dentin-containing tooth 0.000108694626057619 10 71 3 0.0422535211267606 0.3
GO:BP GO:0034651 cortisol biosynthetic process 0.000108694626057619 10 71 3 0.0422535211267606 0.3
GO:BP GO:0031943 regulation of glucocorticoid metabolic process 0.000108694626057619 10 71 3 0.0422535211267606 0.3
GO:BP GO:0032342 aldosterone biosynthetic process 0.000108694626057619 10 71 3 0.0422535211267606 0.3
GO:BP GO:1902645 tertiary alcohol biosynthetic process 0.000108694626057619 10 71 3 0.0422535211267606 0.3
GO:BP GO:2000726 negative regulation of cardiac muscle cell differentiation 0.000108694626057619 10 71 3 0.0422535211267606 0.3
GO:BP GO:0001932 regulation of protein phosphorylation 0.000117239460674022 1240 89 19 0.213483146067416 0.0153225806451613
GO:BP GO:2000027 regulation of animal organ morphogenesis 0.000120244100213569 184 99 8 0.0808080808080808 0.0434782608695652
GO:BP GO:0048546 digestive tract morphogenesis 0.000123878834675028 45 16 3 0.1875 0.0666666666666667
GO:BP GO:0001568 blood vessel development 0.000123878834675028 792 41 10 0.24390243902439 0.0126262626262626
GO:BP GO:0009611 response to wounding 0.000125598656984535 674 69 12 0.173913043478261 0.0178041543026706
GO:BP GO:0048608 reproductive structure development 0.000125598656984535 429 89 11 0.123595505617978 0.0256410256410256
GO:BP GO:0010894 negative regulation of steroid biosynthetic process 0.000125839088008391 28 84 4 0.0476190476190476 0.142857142857143
GO:BP GO:0060231 mesenchymal to epithelial transition 0.000126094929540477 20 120 4 0.0333333333333333 0.2
GO:BP GO:0072087 renal vesicle development 0.000126094929540477 20 120 4 0.0333333333333333 0.2
GO:BP GO:1902533 positive regulation of intracellular signal transduction 0.000128246391115716 1037 79 16 0.20253164556962 0.0154291224686596
GO:BP GO:0032835 glomerulus development 0.000128246391115716 62 38 4 0.105263157894737 0.0645161290322581
GO:BP GO:0061458 reproductive system development 0.000130126658431943 432 89 11 0.123595505617978 0.025462962962963
GO:BP GO:0030198 extracellular matrix organization 0.000133917746778373 401 134 13 0.0970149253731343 0.0324189526184539
GO:BP GO:0030879 mammary gland development 0.000136316828754837 140 63 6 0.0952380952380952 0.0428571428571429
GO:BP GO:0043062 extracellular structure organization 0.000136446918156577 402 134 13 0.0970149253731343 0.0323383084577114
GO:BP GO:0034650 cortisol metabolic process 0.00013729186334546 11 71 3 0.0422535211267606 0.272727272727273
GO:BP GO:0009790 embryo development 0.00013729186334546 1035 107 19 0.177570093457944 0.0183574879227053
GO:BP GO:0090030 regulation of steroid hormone biosynthetic process 0.00013729186334546 11 71 3 0.0422535211267606 0.272727272727273
GO:BP GO:0021983 pituitary gland development 0.00013729186334546 43 120 5 0.0416666666666667 0.116279069767442
GO:BP GO:0043066 negative regulation of apoptotic process 0.00013729186334546 921 89 16 0.179775280898876 0.0173724212812161
GO:BP GO:0048732 gland development 0.00013729186334546 436 89 11 0.123595505617978 0.0252293577981651
GO:BP GO:0045229 external encapsulating structure organization 0.000140012426649433 404 134 13 0.0970149253731343 0.0321782178217822
GO:BP GO:0014070 response to organic cyclic compound 0.000146325246654096 967 95 17 0.178947368421053 0.0175801447776629
GO:BP GO:0072175 epithelial tube formation 0.000146616741459202 137 99 7 0.0707070707070707 0.0510948905109489
GO:BP GO:0060548 negative regulation of cell death 0.000148069981655309 1038 89 17 0.191011235955056 0.0163776493256262
GO:BP GO:0051147 regulation of muscle cell differentiation 0.000149934877479981 173 79 7 0.0886075949367089 0.0404624277456647
GO:BP GO:0051174 regulation of phosphorus metabolic process 0.000153439539196863 1645 89 22 0.247191011235955 0.0133738601823708
GO:BP GO:0019220 regulation of phosphate metabolic process 0.000153439539196863 1645 89 22 0.247191011235955 0.0133738601823708
GO:BP GO:0061041 regulation of wound healing 0.000153459057612797 136 19 4 0.210526315789474 0.0294117647058824
GO:BP GO:0045833 negative regulation of lipid metabolic process 0.00015412948924448 108 84 6 0.0714285714285714 0.0555555555555556
GO:BP GO:0048592 eye morphogenesis 0.000157179983131951 155 89 7 0.0786516853932584 0.0451612903225806
GO:BP GO:0009605 response to external stimulus 0.000157179983131951 2944 84 30 0.357142857142857 0.0101902173913043
GO:BP GO:0001755 neural crest cell migration 0.000157179983131951 54 99 5 0.0505050505050505 0.0925925925925926
GO:BP GO:0048589 developmental growth 0.000157179983131951 649 86 13 0.151162790697674 0.0200308166409861
GO:BP GO:0001944 vasculature development 0.000160606438489435 830 89 15 0.168539325842697 0.0180722891566265
GO:BP GO:0051148 negative regulation of muscle cell differentiation 0.000160606438489435 68 79 5 0.0632911392405063 0.0735294117647059
GO:BP GO:0051055 negative regulation of lipid biosynthetic process 0.000160606438489435 64 84 5 0.0595238095238095 0.078125
GO:BP GO:1905207 regulation of cardiocyte differentiation 0.000160606438489435 36 71 4 0.0563380281690141 0.111111111111111
GO:BP GO:0010243 response to organonitrogen compound 0.000160606438489435 1085 95 18 0.189473684210526 0.0165898617511521
GO:BP GO:0003205 cardiac chamber development 0.000161498343271102 161 120 8 0.0666666666666667 0.0496894409937888
GO:BP GO:0048645 animal organ formation 0.000161611574685168 66 140 6 0.0428571428571429 0.0909090909090909
GO:BP GO:0071230 cellular response to amino acid stimulus 0.000161771187082236 68 136 6 0.0441176470588235 0.0882352941176471
GO:BP GO:0048522 positive regulation of cellular process 0.000161771187082236 5757 89 48 0.539325842696629 0.00833767587285044
GO:BP GO:0030325 adrenal gland development 0.00016446736606223 22 120 4 0.0333333333333333 0.181818181818182
GO:BP GO:0045939 negative regulation of steroid metabolic process 0.000165069699142399 31 84 4 0.0476190476190476 0.129032258064516
GO:BP GO:0001654 eye development 0.000166317957427987 379 125 12 0.096 0.0316622691292876
GO:BP GO:0043069 negative regulation of programmed cell death 0.000167522158504957 943 89 16 0.179775280898876 0.0169671261930011
GO:BP GO:0030509 BMP signaling pathway 0.000168839834648634 158 89 7 0.0786516853932584 0.0443037974683544
GO:BP GO:0007178 transmembrane receptor protein serine/threonine kinase signaling pathway 0.000174730503436041 369 89 10 0.112359550561798 0.02710027100271
GO:BP GO:0072124 regulation of glomerular mesangial cell proliferation 0.000176320643715987 10 89 3 0.0337078651685393 0.3
GO:BP GO:0048638 regulation of developmental growth 0.000178748155084338 340 77 9 0.116883116883117 0.0264705882352941
GO:BP GO:0150063 visual system development 0.00017962261954345 383 125 12 0.096 0.031331592689295
GO:BP GO:0031399 regulation of protein modification process 0.00017962261954345 1671 89 22 0.247191011235955 0.0131657690005984
GO:BP GO:0003323 type B pancreatic cell development 0.000180333308433969 21 41 3 0.0731707317073171 0.142857142857143
GO:BP GO:0042325 regulation of phosphorylation 0.000203448073501196 1431 89 20 0.224719101123595 0.0139762403913347
GO:BP GO:0034309 primary alcohol biosynthetic process 0.000205156067354483 13 71 3 0.0422535211267606 0.230769230769231
GO:BP GO:0008212 mineralocorticoid metabolic process 0.000205156067354483 13 71 3 0.0422535211267606 0.230769230769231
GO:BP GO:0006705 mineralocorticoid biosynthetic process 0.000205156067354483 13 71 3 0.0422535211267606 0.230769230769231
GO:BP GO:0048880 sensory system development 0.000205414250788764 389 125 12 0.096 0.0308483290488432
GO:BP GO:0031214 biomineral tissue development 0.000205777764598709 164 89 7 0.0786516853932584 0.0426829268292683
GO:BP GO:2000241 regulation of reproductive process 0.000212779613987649 165 89 7 0.0786516853932584 0.0424242424242424
GO:BP GO:0090100 positive regulation of transmembrane receptor protein serine/threonine kinase signaling pathway 0.000212779613987649 110 89 6 0.0674157303370786 0.0545454545454545
GO:BP GO:0110148 biomineralization 0.00022038240673232 166 89 7 0.0786516853932584 0.0421686746987952
GO:BP GO:0060443 mammary gland morphogenesis 0.000222328101174827 45 63 4 0.0634920634920635 0.0888888888888889
GO:BP GO:0051154 negative regulation of striated muscle cell differentiation 0.000222328101174827 40 71 4 0.0563380281690141 0.1
GO:BP GO:0072110 glomerular mesangial cell proliferation 0.000228463852424168 11 89 3 0.0337078651685393 0.272727272727273
GO:BP GO:0072537 fibroblast activation 0.000228463852424168 12 81 3 0.037037037037037 0.25
GO:BP GO:0016331 morphogenesis of embryonic epithelium 0.000235917501275095 151 99 7 0.0707070707070707 0.0463576158940397
GO:BP GO:0043009 chordate embryonic development 0.000242001976203459 616 18 6 0.333333333333333 0.00974025974025974
GO:BP GO:0035148 tube formation 0.000243055036984511 152 99 7 0.0707070707070707 0.0460526315789474
GO:BP GO:1905208 negative regulation of cardiocyte differentiation 0.000247895667510577 14 71 3 0.0422535211267606 0.214285714285714
GO:BP GO:0007423 sensory organ development 0.000252114724470712 567 89 12 0.134831460674157 0.0211640211640212
GO:BP GO:0045662 negative regulation of myoblast differentiation 0.000254930888624495 24 41 3 0.0731707317073171 0.125
GO:BP GO:0043410 positive regulation of MAPK cascade 0.000255188747857169 539 79 11 0.139240506329114 0.0204081632653061
GO:BP GO:0009799 specification of symmetry 0.000261885061123136 135 76 6 0.0789473684210526 0.0444444444444444
GO:BP GO:0007528 neuromuscular junction development 0.000261885061123136 48 128 5 0.0390625 0.104166666666667
GO:BP GO:0090287 regulation of cellular response to growth factor stimulus 0.000265252487100889 315 88 9 0.102272727272727 0.0285714285714286
GO:BP GO:0001701 in utero embryonic development 0.000265558503543555 365 18 5 0.277777777777778 0.0136986301369863
GO:BP GO:0003203 endocardial cushion morphogenesis 0.00026690363695303 34 89 4 0.0449438202247191 0.117647058823529
GO:BP GO:0048048 embryonic eye morphogenesis 0.00026690363695303 34 89 4 0.0449438202247191 0.117647058823529
GO:BP GO:0060348 bone development 0.000267415838983918 203 76 7 0.0921052631578947 0.0344827586206897
GO:BP GO:0071229 cellular response to acid chemical 0.000267415838983918 76 81 5 0.0617283950617284 0.0657894736842105
GO:BP GO:0035137 hindlimb morphogenesis 0.000273495187039384 35 29 3 0.103448275862069 0.0857142857142857
GO:BP GO:0009792 embryo development ending in birth or egg hatching 0.000274054082410382 635 18 6 0.333333333333333 0.0094488188976378
GO:BP GO:0090183 regulation of kidney development 0.000274736209151944 31 99 4 0.0404040404040404 0.129032258064516
GO:BP GO:0048514 blood vessel morphogenesis 0.000276014931291989 711 41 9 0.219512195121951 0.0126582278481013
GO:BP GO:0048568 embryonic organ development 0.000276014931291989 432 99 11 0.111111111111111 0.025462962962963
GO:BP GO:0072273 metanephric nephron morphogenesis 0.000279031557423593 26 120 4 0.0333333333333333 0.153846153846154
GO:BP GO:0061308 cardiac neural crest cell development involved in heart development 0.000279031557423593 12 89 3 0.0337078651685393 0.25
GO:BP GO:0072202 cell differentiation involved in metanephros development 0.000279031557423593 26 120 4 0.0333333333333333 0.153846153846154
GO:BP GO:0061307 cardiac neural crest cell differentiation involved in heart development 0.000279031557423593 12 89 3 0.0337078651685393 0.25
GO:BP GO:0032270 positive regulation of cellular protein metabolic process 0.000282062429422884 1477 89 20 0.224719101123595 0.01354096140826
GO:BP GO:0043405 regulation of MAP kinase activity 0.000282062429422884 316 89 9 0.101123595505618 0.0284810126582278
GO:BP GO:0046184 aldehyde biosynthetic process 0.000286143615089414 15 71 3 0.0422535211267606 0.2
GO:BP GO:0051145 smooth muscle cell differentiation 0.000290342592217645 80 79 5 0.0632911392405063 0.0625
GO:BP GO:0031016 pancreas development 0.000303016754258564 77 41 4 0.0975609756097561 0.051948051948052
GO:BP GO:0003158 endothelium development 0.000303016754258564 143 45 5 0.111111111111111 0.034965034965035
GO:BP GO:0050921 positive regulation of chemotaxis 0.000308390296509287 141 23 4 0.173913043478261 0.0283687943262411
GO:BP GO:0014068 positive regulation of phosphatidylinositol 3-kinase signaling 0.000308390296509287 93 69 5 0.072463768115942 0.0537634408602151
GO:BP GO:0097191 extrinsic apoptotic signaling pathway 0.000333267088653741 223 99 8 0.0808080808080808 0.0358744394618834
GO:BP GO:0002068 glandular epithelial cell development 0.000333267088653741 27 41 3 0.0731707317073171 0.111111111111111
GO:BP GO:0003309 type B pancreatic cell differentiation 0.000333267088653741 27 41 3 0.0731707317073171 0.111111111111111
GO:BP GO:0032965 regulation of collagen biosynthetic process 0.000333267088653741 47 69 4 0.0579710144927536 0.0851063829787234
GO:BP GO:1901699 cellular response to nitrogen compound 0.000337658983623218 724 85 13 0.152941176470588 0.0179558011049724
GO:BP GO:0001759 organ induction 0.000350564933814573 24 140 4 0.0285714285714286 0.166666666666667
GO:BP GO:1901698 response to nitrogen compound 0.000357152272049577 1172 95 18 0.189473684210526 0.015358361774744
GO:BP GO:0050794 regulation of cellular process 0.000361836659738643 11473 89 74 0.831460674157303 0.00644992591301316
GO:BP GO:0043067 regulation of programmed cell death 0.000376861108796685 1582 99 22 0.222222222222222 0.0139064475347661
GO:BP GO:0050678 regulation of epithelial cell proliferation 0.000376861108796685 401 18 5 0.277777777777778 0.0124688279301746
GO:BP GO:0048593 camera-type eye morphogenesis 0.00038983888318028 126 89 6 0.0674157303370786 0.0476190476190476
GO:BP GO:0010566 regulation of ketone biosynthetic process 0.000401486300982927 17 71 3 0.0422535211267606 0.176470588235294
GO:BP GO:0042481 regulation of odontogenesis 0.000401486300982927 17 71 3 0.0422535211267606 0.176470588235294
GO:BP GO:0048518 positive regulation of biological process 0.000404371604243401 6363 89 50 0.561797752808989 0.00785792865000786
GO:BP GO:1901722 regulation of cell proliferation involved in kidney development 0.000424748973265234 14 89 3 0.0337078651685393 0.214285714285714
GO:BP GO:0071676 negative regulation of mononuclear cell migration 0.000435122885990175 22 56 3 0.0535714285714286 0.136363636363636
GO:BP GO:0010941 regulation of cell death 0.000435122885990175 1720 99 23 0.232323232323232 0.0133720930232558
GO:BP GO:0002683 negative regulation of immune system process 0.000438379294953061 420 56 8 0.142857142857143 0.019047619047619
GO:BP GO:0035883 enteroendocrine cell differentiation 0.000438379294953061 30 41 3 0.0731707317073171 0.1
GO:BP GO:0022603 regulation of anatomical structure morphogenesis 0.00044449165973897 1042 89 16 0.179775280898876 0.0153550863723608
GO:BP GO:0033002 muscle cell proliferation 0.000445600869680565 244 95 8 0.0842105263157895 0.0327868852459016
GO:BP GO:0120178 steroid hormone biosynthetic process 0.000452058183727642 50 71 4 0.0563380281690141 0.08
GO:BP GO:0010712 regulation of collagen metabolic process 0.000461217935142073 52 69 4 0.0579710144927536 0.0769230769230769
GO:BP GO:2001234 negative regulation of apoptotic signaling pathway 0.000461217935142073 236 99 8 0.0808080808080808 0.0338983050847458
GO:BP GO:0040013 negative regulation of locomotion 0.000461217935142073 401 76 9 0.118421052631579 0.0224438902743142
GO:BP GO:0006704 glucocorticoid biosynthetic process 0.000461217935142073 18 71 3 0.0422535211267606 0.166666666666667
GO:BP GO:0007494 midgut development 0.000495164347987008 13 103 3 0.029126213592233 0.230769230769231
GO:BP GO:0001525 angiogenesis 0.000496245070948701 617 51 9 0.176470588235294 0.0145867098865478
GO:BP GO:0033674 positive regulation of kinase activity 0.000499996883112061 608 77 11 0.142857142857143 0.0180921052631579
GO:BP GO:0034330 cell junction organization 0.000501483249256696 722 128 16 0.125 0.0221606648199446
GO:BP GO:0048566 embryonic digestive tract development 0.000501826502073441 31 120 4 0.0333333333333333 0.129032258064516
GO:BP GO:0060395 SMAD protein signal transduction 0.000515032688544897 82 89 5 0.0561797752808989 0.0609756097560976
GO:BP GO:0050808 synapse organization 0.000515483399775849 428 128 12 0.09375 0.0280373831775701
GO:BP GO:0010463 mesenchymal cell proliferation 0.000522859136841522 42 89 4 0.0449438202247191 0.0952380952380952
GO:BP GO:0051247 positive regulation of protein metabolic process 0.000555756306172128 1564 89 20 0.224719101123595 0.0127877237851662
GO:BP GO:0035296 regulation of tube diameter 0.000559402983541604 135 90 6 0.0666666666666667 0.0444444444444444
GO:BP GO:0003338 metanephros morphogenesis 0.000559402983541604 32 120 4 0.0333333333333333 0.125
GO:BP GO:0097746 blood vessel diameter maintenance 0.000559402983541604 135 90 6 0.0666666666666667 0.0444444444444444
GO:BP GO:0035150 regulation of tube size 0.00057992545193253 136 90 6 0.0666666666666667 0.0441176470588235
GO:BP GO:0060349 bone morphogenesis 0.000581580855530515 99 76 5 0.0657894736842105 0.0505050505050505
GO:BP GO:0032964 collagen biosynthetic process 0.000591212185790957 56 69 4 0.0579710144927536 0.0714285714285714
GO:BP GO:0043406 positive regulation of MAP kinase activity 0.0005913341827544 234 77 7 0.0909090909090909 0.0299145299145299
GO:BP GO:0072109 glomerular mesangium development 0.0005913341827544 16 89 3 0.0337078651685393 0.1875
GO:BP GO:0071417 cellular response to organonitrogen compound 0.00059899196209229 666 85 12 0.141176470588235 0.018018018018018
GO:BP GO:1902644 tertiary alcohol metabolic process 0.000601857611663065 20 71 3 0.0422535211267606 0.15
GO:BP GO:0050790 regulation of catalytic activity 0.000608631415434369 2545 99 29 0.292929292929293 0.0113948919449902
GO:BP GO:0007155 cell adhesion 0.000630581208257171 1492 94 20 0.212765957446809 0.0134048257372654
GO:BP GO:0050673 epithelial cell proliferation 0.000641306755512676 460 18 5 0.277777777777778 0.0108695652173913
GO:BP GO:0050819 negative regulation of coagulation 0.000657386136680464 56 26 3 0.115384615384615 0.0535714285714286
GO:BP GO:0030595 leukocyte chemotaxis 0.000660917363530864 227 56 6 0.107142857142857 0.026431718061674
GO:BP GO:0034754 cellular hormone metabolic process 0.000661152221257975 140 90 6 0.0666666666666667 0.0428571428571429
GO:BP GO:0022610 biological adhesion 0.000664729100362983 1499 94 20 0.212765957446809 0.0133422281521014
GO:BP GO:0030155 regulation of cell adhesion 0.000665092699582044 748 89 13 0.146067415730337 0.017379679144385
GO:BP GO:0060272 embryonic skeletal joint morphogenesis 0.000665092699582044 11 140 3 0.0214285714285714 0.272727272727273
GO:BP GO:0050878 regulation of body fluid levels 0.000669775650808431 514 9 4 0.444444444444444 0.00778210116731518
GO:BP GO:0046885 regulation of hormone biosynthetic process 0.000676344215978049 21 71 3 0.0422535211267606 0.142857142857143
GO:BP GO:0035282 segmentation 0.000712032677229656 98 42 4 0.0952380952380952 0.0408163265306122
GO:BP GO:0003337 mesenchymal to epithelial transition involved in metanephros morphogenesis 0.000712736832487374 13 120 3 0.025 0.230769230769231
GO:BP GO:0042981 regulation of apoptotic process 0.000727170406725713 1549 99 21 0.212121212121212 0.013557133634603
GO:BP GO:0032147 activation of protein kinase activity 0.000737187405803723 331 77 8 0.103896103896104 0.0241691842900302
GO:BP GO:0045860 positive regulation of protein kinase activity 0.000776946826958609 534 77 10 0.12987012987013 0.0187265917602996
GO:BP GO:0061036 positive regulation of cartilage development 0.000823620107589138 31 140 4 0.0285714285714286 0.129032258064516
GO:BP GO:0048562 embryonic organ morphogenesis 0.000844643936954945 292 89 8 0.0898876404494382 0.0273972602739726
GO:BP GO:0061180 mammary gland epithelium development 0.000864963490811569 69 63 4 0.0634920634920635 0.0579710144927536
GO:BP GO:0048146 positive regulation of fibroblast proliferation 0.000876427606232251 51 32 3 0.09375 0.0588235294117647
GO:BP GO:0006954 inflammatory response 0.000903071497833239 794 87 13 0.149425287356322 0.0163727959697733
GO:BP GO:0006468 protein phosphorylation 0.000913972725769078 1668 94 21 0.223404255319149 0.012589928057554
GO:BP GO:0072074 kidney mesenchyme development 0.000925651000055229 19 89 3 0.0337078651685393 0.157894736842105
GO:BP GO:0060973 cell migration involved in heart development 0.000925651000055229 19 89 3 0.0337078651685393 0.157894736842105
GO:BP GO:0051179 localization 0.000927478733820531 6901 111 62 0.558558558558559 0.00898420518765396
GO:BP GO:0030336 negative regulation of cell migration 0.000992213398847584 353 76 8 0.105263157894737 0.0226628895184136
GO:BP GO:0014020 primary neural tube formation 0.000992213398847584 97 18 3 0.166666666666667 0.0309278350515464
GO:BP GO:0048640 negative regulation of developmental growth 0.000992213398847584 112 77 5 0.0649350649350649 0.0446428571428571
GO:BP GO:0060039 pericardium development 0.0010581909583205 20 89 3 0.0337078651685393 0.15
GO:BP GO:0008211 glucocorticoid metabolic process 0.00106339415596661 25 71 3 0.0422535211267606 0.12
GO:BP GO:0120255 olefinic compound biosynthetic process 0.00106339415596661 25 71 3 0.0422535211267606 0.12
GO:BP GO:0002066 columnar/cuboidal epithelial cell development 0.00106339415596661 43 41 3 0.0731707317073171 0.0697674418604651
GO:BP GO:0002064 epithelial cell development 0.00107968806087523 218 41 5 0.121951219512195 0.0229357798165138
GO:BP GO:0019722 calcium-mediated signaling 0.00108995020789122 211 67 6 0.0895522388059701 0.028436018957346
GO:BP GO:0021536 diencephalon development 0.00111091069930901 74 120 5 0.0416666666666667 0.0675675675675676
GO:BP GO:0001709 cell fate determination 0.00112905228605208 44 41 3 0.0731707317073171 0.0681818181818182
GO:BP GO:0040008 regulation of growth 0.00115013806061941 681 77 11 0.142857142857143 0.0161527165932452
GO:BP GO:0006915 apoptotic process 0.00117107183436166 1990 99 24 0.242424242424242 0.0120603015075377
GO:BP GO:0071407 cellular response to organic cyclic compound 0.00117107183436166 587 89 11 0.123595505617978 0.0187393526405451
GO:BP GO:0042445 hormone metabolic process 0.00117691260212544 228 90 7 0.0777777777777778 0.0307017543859649
GO:BP GO:0048871 multicellular organismal homeostasis 0.0011831584568649 530 53 8 0.150943396226415 0.0150943396226415
GO:BP GO:0032967 positive regulation of collagen biosynthetic process 0.0011980948163134 27 69 3 0.0434782608695652 0.111111111111111
GO:BP GO:0001841 neural tube formation 0.0011980948163134 105 18 3 0.166666666666667 0.0285714285714286
GO:BP GO:0031175 neuron projection development 0.0011980948163134 1012 101 16 0.158415841584158 0.0158102766798419
GO:BP GO:0010717 regulation of epithelial to mesenchymal transition 0.00120678114399058 102 89 5 0.0561797752808989 0.0490196078431373
GO:BP GO:0072283 metanephric renal vesicle morphogenesis 0.00122691096434823 16 120 3 0.025 0.1875
GO:BP GO:0051347 positive regulation of transferase activity 0.00123302087653913 689 77 11 0.142857142857143 0.0159651669085631
GO:BP GO:0032268 regulation of cellular protein metabolic process 0.00123675950957482 2541 89 26 0.292134831460674 0.0102321920503739
GO:BP GO:0007204 positive regulation of cytosolic calcium ion concentration 0.00123675950957482 325 109 9 0.0825688073394495 0.0276923076923077
GO:BP GO:0014066 regulation of phosphatidylinositol 3-kinase signaling 0.00123675950957482 133 69 5 0.072463768115942 0.037593984962406
GO:BP GO:2000146 negative regulation of cell motility 0.00125321660122764 369 76 8 0.105263157894737 0.021680216802168
GO:BP GO:0050789 regulation of biological process 0.00126364489643484 12091 89 75 0.842696629213483 0.00620296087999338
GO:BP GO:0008217 regulation of blood pressure 0.00126686653896293 193 108 7 0.0648148148148148 0.0362694300518135
GO:BP GO:0006700 C21-steroid hormone biosynthetic process 0.0012681790259074 27 71 3 0.0422535211267606 0.111111111111111
GO:BP GO:0048666 neuron development 0.00127583348231891 1149 128 20 0.15625 0.0174064403829417
GO:BP GO:0060688 regulation of morphogenesis of a branching structure 0.00127583348231891 50 99 4 0.0404040404040404 0.08
GO:BP GO:0010714 positive regulation of collagen metabolic process 0.00129289631168399 28 69 3 0.0434782608695652 0.107142857142857
GO:BP GO:0051246 regulation of protein metabolic process 0.00130755003968124 2704 89 27 0.303370786516854 0.00998520710059172
GO:BP GO:0043200 response to amino acid 0.00131107344797887 115 81 5 0.0617283950617284 0.0434782608695652
GO:BP GO:0012501 programmed cell death 0.00131536088129997 2143 99 25 0.252525252525253 0.0116658889407373
GO:BP GO:2001233 regulation of apoptotic signaling pathway 0.00132406989967575 363 99 9 0.0909090909090909 0.0247933884297521
GO:BP GO:0040007 growth 0.00136439494281653 967 86 14 0.162790697674419 0.0144777662874871
GO:BP GO:0042446 hormone biosynthetic process 0.00136439494281653 71 71 4 0.0563380281690141 0.0563380281690141
GO:BP GO:0019233 sensory perception of pain 0.00138780952880675 106 19 3 0.157894736842105 0.0283018867924528
GO:BP GO:0009952 anterior/posterior pattern specification 0.00139329659333716 211 71 6 0.0845070422535211 0.028436018957346
GO:BP GO:0051271 negative regulation of cellular component movement 0.00140609590067436 377 76 8 0.105263157894737 0.0212201591511936
GO:BP GO:0042060 wound healing 0.00142076029088977 549 82 10 0.121951219512195 0.0182149362477231
GO:BP GO:0010092 specification of animal organ identity 0.00143973400339765 37 140 4 0.0285714285714286 0.108108108108108
GO:BP GO:0031018 endocrine pancreas development 0.00143973400339765 49 41 3 0.0731707317073171 0.0612244897959184
GO:BP GO:0060603 mammary gland duct morphogenesis 0.00143973400339765 32 63 3 0.0476190476190476 0.09375
GO:BP GO:0008219 cell death 0.00144543344821975 2292 99 26 0.262626262626263 0.0113438045375218
GO:BP GO:0072498 embryonic skeletal joint development 0.00148443619251743 15 140 3 0.0214285714285714 0.2
GO:BP GO:1904894 positive regulation of receptor signaling pathway via STAT 0.00148649476367996 50 104 4 0.0384615384615385 0.08
GO:BP GO:0090189 regulation of branching involved in ureteric bud morphogenesis 0.00149718335537914 21 99 3 0.0303030303030303 0.142857142857143
GO:BP GO:0048639 positive regulation of developmental growth 0.00150842218517529 184 53 5 0.0943396226415094 0.0271739130434783
GO:BP GO:0019932 second-messenger-mediated signaling 0.00152926547554541 327 67 7 0.104477611940299 0.0214067278287462
GO:BP GO:0098609 cell-cell adhesion 0.00152926547554541 894 94 14 0.148936170212766 0.0156599552572707
GO:BP GO:0051046 regulation of secretion 0.00154324043756003 647 71 10 0.140845070422535 0.0154559505409583
GO:BP GO:0048661 positive regulation of smooth muscle cell proliferation 0.0015706829980219 103 95 5 0.0526315789473684 0.0485436893203883
GO:BP GO:0043085 positive regulation of catalytic activity 0.00160983612989925 1418 99 19 0.191919191919192 0.0133991537376587
GO:BP GO:0061035 regulation of cartilage development 0.00166087402716925 71 140 5 0.0357142857142857 0.0704225352112676
GO:BP GO:0061053 somite development 0.00169543946517336 86 63 4 0.0634920634920635 0.0465116279069767
GO:BP GO:2000242 negative regulation of reproductive process 0.00170397291601345 61 89 4 0.0449438202247191 0.0655737704918033
GO:BP GO:0043408 regulation of MAPK cascade 0.00170826062141974 730 89 12 0.134831460674157 0.0164383561643836
GO:BP GO:0034329 cell junction assembly 0.00170826062141974 438 86 9 0.104651162790698 0.0205479452054795
GO:BP GO:0009893 positive regulation of metabolic process 0.00171590077019309 3783 29 15 0.517241379310345 0.00396510705789056
GO:BP GO:0071560 cellular response to transforming growth factor beta stimulus 0.00182473503647835 256 88 7 0.0795454545454545 0.02734375
GO:BP GO:0009855 determination of bilateral symmetry 0.00182622922542971 134 76 5 0.0657894736842105 0.0373134328358209
GO:BP GO:0045446 endothelial cell differentiation 0.00188414394467149 125 82 5 0.0609756097560976 0.04
GO:BP GO:0048596 embryonic camera-type eye morphogenesis 0.00199401776908255 26 89 3 0.0337078651685393 0.115384615384615
GO:BP GO:1901888 regulation of cell junction assembly 0.00199401776908255 202 113 7 0.0619469026548673 0.0346534653465347
GO:BP GO:0042592 homeostatic process 0.00204124107157456 1981 41 13 0.317073170731707 0.00656234225138819
GO:BP GO:0035850 epithelial cell differentiation involved in kidney development 0.00204541239154791 48 120 4 0.0333333333333333 0.0833333333333333
GO:BP GO:0071559 response to transforming growth factor beta 0.00205289571910632 262 88 7 0.0795454545454545 0.0267175572519084
GO:BP GO:0007416 synapse assembly 0.00209371923864193 180 128 7 0.0546875 0.0388888888888889
GO:BP GO:0003006 developmental process involved in reproduction 0.00209371923864193 982 89 14 0.157303370786517 0.0142566191446029
GO:BP GO:0065007 biological regulation 0.0021010127428774 12809 90 78 0.866666666666667 0.00608946834257163
GO:BP GO:0090596 sensory organ morphogenesis 0.00217448246921244 262 89 7 0.0786516853932584 0.0267175572519084
GO:BP GO:0009612 response to mechanical stimulus 0.00217448246921244 218 76 6 0.0789473684210526 0.0275229357798165
GO:BP GO:1903035 negative regulation of response to wounding 0.00217448246921244 93 63 4 0.0634920634920635 0.043010752688172
GO:BP GO:0048660 regulation of smooth muscle cell proliferation 0.00217928871824758 174 95 6 0.0631578947368421 0.0344827586206897
GO:BP GO:0002682 regulation of immune system process 0.00218061754602296 1617 56 14 0.25 0.00865800865800866
GO:BP GO:0010817 regulation of hormone levels 0.00218281304347172 536 12 4 0.333333333333333 0.00746268656716418
GO:BP GO:0022612 gland morphogenesis 0.00218418801435393 120 89 5 0.0561797752808989 0.0416666666666667
GO:BP GO:0009880 embryonic pattern specification 0.00218418801435393 67 89 4 0.0449438202247191 0.0597014925373134
GO:BP GO:0050679 positive regulation of epithelial cell proliferation 0.00218418801435393 213 12 3 0.25 0.0140845070422535
GO:BP GO:0048659 smooth muscle cell proliferation 0.00218418801435393 176 95 6 0.0631578947368421 0.0340909090909091
GO:BP GO:0051480 regulation of cytosolic calcium ion concentration 0.00218418801435393 360 109 9 0.0825688073394495 0.025
GO:BP GO:0098801 regulation of renal system process 0.00218418801435393 35 69 3 0.0434782608695652 0.0857142857142857
GO:BP GO:0019218 regulation of steroid metabolic process 0.00226250349042014 130 84 5 0.0595238095238095 0.0384615384615385
GO:BP GO:0032350 regulation of hormone metabolic process 0.00226250349042014 35 71 3 0.0422535211267606 0.0857142857142857
GO:BP GO:0001101 response to acid chemical 0.00226595076593829 135 81 5 0.0617283950617284 0.037037037037037
GO:BP GO:0060411 cardiac septum morphogenesis 0.00227169076732629 68 89 4 0.0449438202247191 0.0588235294117647
GO:BP GO:0010604 positive regulation of macromolecule metabolic process 0.00229745380266901 3483 32 15 0.46875 0.00430663221360896
GO:BP GO:0006874 cellular calcium ion homeostasis 0.00232528137788496 460 87 9 0.103448275862069 0.0195652173913043
GO:BP GO:0014065 phosphatidylinositol 3-kinase signaling 0.0023787612848213 161 69 5 0.072463768115942 0.031055900621118
GO:BP GO:2000243 positive regulation of reproductive process 0.00238271888676491 81 76 4 0.0526315789473684 0.0493827160493827
GO:BP GO:0014823 response to activity 0.00238271888676491 76 81 4 0.0493827160493827 0.0526315789473684
GO:BP GO:0030858 positive regulation of epithelial cell differentiation 0.00238271888676491 67 38 3 0.0789473684210526 0.0447761194029851
GO:BP GO:0034308 primary alcohol metabolic process 0.00240056565940132 95 117 5 0.0427350427350427 0.0526315789473684
GO:BP GO:0071902 positive regulation of protein serine/threonine kinase activity 0.0024743837206806 316 77 7 0.0909090909090909 0.0221518987341772
GO:BP GO:0045604 regulation of epidermal cell differentiation 0.0024743837206806 63 41 3 0.0731707317073171 0.0476190476190476
GO:BP GO:0003018 vascular process in circulatory system 0.00252297691645872 256 95 7 0.0736842105263158 0.02734375
GO:BP GO:0060041 retina development in camera-type eye 0.00257893773947565 155 41 4 0.0975609756097561 0.0258064516129032
GO:BP GO:0002686 negative regulation of leukocyte migration 0.00259959006022764 47 56 3 0.0535714285714286 0.0638297872340425
GO:BP GO:0003013 circulatory system process 0.00259982832359395 637 108 12 0.111111111111111 0.0188383045525903
GO:BP GO:0008015 blood circulation 0.00260503407032994 553 90 10 0.111111111111111 0.0180831826401447
GO:BP GO:0001961 positive regulation of cytokine-mediated signaling pathway 0.00263608875926771 50 53 3 0.0566037735849057 0.06
GO:BP GO:0060350 endochondral bone morphogenesis 0.00267868419116086 58 46 3 0.0652173913043478 0.0517241379310345
GO:BP GO:0061311 cell surface receptor signaling pathway involved in heart development 0.00270007406461236 32 84 3 0.0357142857142857 0.09375
GO:BP GO:0055074 calcium ion homeostasis 0.00270751217698293 472 87 9 0.103448275862069 0.0190677966101695
GO:BP GO:0030324 lung development 0.00271949140941003 173 16 3 0.1875 0.0173410404624277
GO:BP GO:0009581 detection of external stimulus 0.00273655930388324 145 19 3 0.157894736842105 0.0206896551724138
GO:BP GO:0010628 positive regulation of gene expression 0.00274641207350201 1160 79 14 0.177215189873418 0.0120689655172414
GO:BP GO:0031325 positive regulation of cellular metabolic process 0.0027625512094312 3274 79 27 0.341772151898734 0.00824679291386683
GO:BP GO:0009953 dorsal/ventral pattern formation 0.00282373605173047 83 140 5 0.0357142857142857 0.0602409638554217
GO:BP GO:0061384 heart trabecula morphogenesis 0.00286242303042967 31 89 3 0.0337078651685393 0.0967741935483871
GO:BP GO:0030323 respiratory tube development 0.00286532963519121 177 16 3 0.1875 0.0169491525423729
GO:BP GO:0032103 positive regulation of response to external stimulus 0.00289625316787956 513 36 6 0.166666666666667 0.0116959064327485
GO:BP GO:0048145 regulation of fibroblast proliferation 0.00293046915169337 87 32 3 0.09375 0.0344827586206897
GO:BP GO:0045664 regulation of neuron differentiation 0.0029321161260465 202 89 6 0.0674157303370786 0.0297029702970297
GO:BP GO:0021915 neural tube development 0.00293252983537832 158 18 3 0.166666666666667 0.0189873417721519
GO:BP GO:0007517 muscle organ development 0.00296319553908389 333 76 7 0.0921052631578947 0.021021021021021
GO:BP GO:0000302 response to reactive oxygen species 0.00296319553908389 237 139 8 0.0575539568345324 0.0337552742616034
GO:BP GO:0048144 fibroblast proliferation 0.00296319553908389 88 32 3 0.09375 0.0340909090909091
GO:BP GO:0030856 regulation of epithelial cell differentiation 0.00300742801507005 164 41 4 0.0975609756097561 0.024390243902439
GO:BP GO:0032102 negative regulation of response to external stimulus 0.00300980953779503 406 63 7 0.111111111111111 0.0172413793103448
GO:BP GO:0018108 peptidyl-tyrosine phosphorylation 0.00303649260241723 385 48 6 0.125 0.0155844155844156
GO:BP GO:0045682 regulation of epidermis development 0.00313739963301209 70 41 3 0.0731707317073171 0.0428571428571429
GO:BP GO:0018212 peptidyl-tyrosine modification 0.00314367792537598 388 48 6 0.125 0.0154639175257732
GO:BP GO:0000187 activation of MAPK activity 0.00314367792537598 156 77 5 0.0649350649350649 0.032051282051282
GO:BP GO:0007596 blood coagulation 0.00314965059830304 347 9 3 0.333333333333333 0.00864553314121038
GO:BP GO:0048663 neuron fate commitment 0.00314965059830304 64 45 3 0.0666666666666667 0.046875
GO:BP GO:0009725 response to hormone 0.00316597619861606 921 89 13 0.146067415730337 0.0141150922909881
GO:BP GO:0007599 hemostasis 0.00323202445738402 351 9 3 0.333333333333333 0.00854700854700855
GO:BP GO:0050817 coagulation 0.00329824771345578 354 9 3 0.333333333333333 0.00847457627118644
GO:BP GO:0014909 smooth muscle cell migration 0.00336789603256455 93 32 3 0.09375 0.032258064516129
GO:BP GO:0035116 embryonic hindlimb morphogenesis 0.0033983880536058 28 107 3 0.0280373831775701 0.107142857142857
GO:BP GO:0008207 C21-steroid hormone metabolic process 0.00341690765145239 42 71 3 0.0422535211267606 0.0714285714285714
GO:BP GO:0097529 myeloid leukocyte migration 0.00341849413261309 221 56 5 0.0892857142857143 0.0226244343891403
GO:BP GO:0033081 regulation of T cell differentiation in thymus 0.00349407693258048 24 127 3 0.0236220472440945 0.125
GO:BP GO:0003176 aortic valve development 0.00350795316292513 36 84 3 0.0357142857142857 0.0833333333333333
GO:BP GO:0022414 reproductive process 0.003517304340078 1493 79 16 0.20253164556962 0.0107166778298727
GO:BP GO:0060760 positive regulation of response to cytokine stimulus 0.003517304340078 57 53 3 0.0566037735849057 0.0526315789473684
GO:BP GO:0072503 cellular divalent inorganic cation homeostasis 0.00356854077264076 497 87 9 0.103448275862069 0.0181086519114688
GO:BP GO:0000003 reproduction 0.00357914112752227 1496 79 16 0.20253164556962 0.0106951871657754
GO:BP GO:0003279 cardiac septum development 0.00361135651272616 104 120 5 0.0416666666666667 0.0480769230769231
GO:BP GO:0032330 regulation of chondrocyte differentiation 0.00363191590063886 51 140 4 0.0285714285714286 0.0784313725490196
GO:BP GO:0060541 respiratory system development 0.00368550789279246 199 16 3 0.1875 0.0150753768844221
GO:BP GO:0009890 negative regulation of biosynthetic process 0.00375726253276411 1740 89 19 0.213483146067416 0.0109195402298851
GO:BP GO:0051604 protein maturation 0.00375734107218415 306 42 5 0.119047619047619 0.0163398692810458
GO:BP GO:0050730 regulation of peptidyl-tyrosine phosphorylation 0.0039041406929659 269 48 5 0.104166666666667 0.0185873605947955
GO:BP GO:0019216 regulation of lipid metabolic process 0.00397038176774074 419 84 8 0.0952380952380952 0.0190930787589499
GO:BP GO:0031076 embryonic camera-type eye development 0.00400855545360561 36 89 3 0.0337078651685393 0.0833333333333333
GO:BP GO:0045892 negative regulation of transcription, DNA-templated 0.00403106790914861 1337 89 16 0.179775280898876 0.0119670905011219
GO:BP GO:0065009 regulation of molecular function 0.00404379021318941 3221 99 31 0.313131313131313 0.00962434026699783
GO:BP GO:2000401 regulation of lymphocyte migration 0.00405791620296738 63 51 3 0.0588235294117647 0.0476190476190476
GO:BP GO:0080134 regulation of response to stress 0.00406646199951166 1443 39 10 0.256410256410256 0.00693000693000693
GO:BP GO:1903507 negative regulation of nucleic acid-templated transcription 0.00406714482656673 1339 89 16 0.179775280898876 0.011949215832711
GO:BP GO:0045926 negative regulation of growth 0.00410731509996348 255 77 6 0.0779220779220779 0.0235294117647059
GO:BP GO:1902679 negative regulation of RNA biosynthetic process 0.00411531323813424 1341 89 16 0.179775280898876 0.0119313944817301
GO:BP GO:0030900 forebrain development 0.00415303679869683 385 71 7 0.0985915492957746 0.0181818181818182
GO:BP GO:0030279 negative regulation of ossification 0.00417191416466749 38 86 3 0.0348837209302326 0.0789473684210526
GO:BP GO:0042181 ketone biosynthetic process 0.00417551699838235 46 71 3 0.0422535211267606 0.0652173913043478
GO:BP GO:0050866 negative regulation of cell activation 0.00418667563249253 211 16 3 0.1875 0.014218009478673
GO:BP GO:0001890 placenta development 0.00422971675739823 147 89 5 0.0561797752808989 0.0340136054421769
GO:BP GO:0071900 regulation of protein serine/threonine kinase activity 0.004324601442234 503 89 9 0.101123595505618 0.0178926441351889
GO:BP GO:0072507 divalent inorganic cation homeostasis 0.00436617766857633 516 87 9 0.103448275862069 0.0174418604651163
GO:BP GO:1904018 positive regulation of vasculature development 0.0043726876917136 187 41 4 0.0975609756097561 0.0213903743315508
GO:BP GO:0045766 positive regulation of angiogenesis 0.0043726876917136 187 41 4 0.0975609756097561 0.0213903743315508
GO:BP GO:0014812 muscle cell migration 0.00449361526031972 106 32 3 0.09375 0.0283018867924528
GO:BP GO:0072659 protein localization to plasma membrane 0.0045929922000407 283 28 4 0.142857142857143 0.0141342756183746
GO:BP GO:0006950 response to stress 0.00464326231729612 4170 89 34 0.382022471910112 0.00815347721822542
GO:BP GO:1905314 semi-lunar valve development 0.00464326231729612 41 84 3 0.0357142857142857 0.0731707317073171
GO:BP GO:0009948 anterior/posterior axis specification 0.00466720070526072 53 65 3 0.0461538461538462 0.0566037735849057
GO:BP GO:1901099 negative regulation of signal transduction in absence of ligand 0.00467497232748158 35 99 3 0.0303030303030303 0.0857142857142857
GO:BP GO:2001240 negative regulation of extrinsic apoptotic signaling pathway in absence of ligand 0.00467497232748158 35 99 3 0.0303030303030303 0.0857142857142857
GO:BP GO:0010001 glial cell differentiation 0.00467804785250175 225 124 7 0.0564516129032258 0.0311111111111111
GO:BP GO:0007422 peripheral nervous system development 0.00470606883543588 79 99 4 0.0404040404040404 0.0506329113924051
GO:BP GO:0048015 phosphatidylinositol-mediated signaling 0.00471563343291266 197 69 5 0.072463768115942 0.0253807106598985
GO:BP GO:0032963 collagen metabolic process 0.00478162940657043 114 69 4 0.0579710144927536 0.0350877192982456
GO:BP GO:0006979 response to oxidative stress 0.00480218698343188 466 139 11 0.079136690647482 0.0236051502145923
GO:BP GO:0006875 cellular metal ion homeostasis 0.00486661372078851 593 110 11 0.1 0.0185497470489039
GO:BP GO:0051302 regulation of cell division 0.00493682629154723 174 79 5 0.0632911392405063 0.028735632183908
GO:BP GO:0001894 tissue homeostasis 0.00493682629154723 270 105 7 0.0666666666666667 0.0259259259259259
GO:BP GO:0035265 organ growth 0.00498984889257097 182 76 5 0.0657894736842105 0.0274725274725275
GO:BP GO:0048017 inositol lipid-mediated signaling 0.0050112889366856 201 69 5 0.072463768115942 0.0248756218905473
GO:BP GO:0051173 positive regulation of nitrogen compound metabolic process 0.00509927951094516 3083 79 25 0.316455696202532 0.00810898475510866
GO:BP GO:0008202 steroid metabolic process 0.00513878973277772 342 84 7 0.0833333333333333 0.0204678362573099
GO:BP GO:0042733 embryonic digit morphogenesis 0.00513878973277772 58 140 4 0.0285714285714286 0.0689655172413793
GO:BP GO:1902531 regulation of intracellular signal transduction 0.00520153526849431 1842 94 20 0.212765957446809 0.01085776330076
GO:BP GO:0050810 regulation of steroid biosynthetic process 0.00524053912639574 97 84 4 0.0476190476190476 0.0412371134020619
GO:BP GO:1902106 negative regulation of leukocyte differentiation 0.0052739145394283 105 35 3 0.0857142857142857 0.0285714285714286
GO:BP GO:0048708 astrocyte differentiation 0.00550714481333001 78 106 4 0.0377358490566038 0.0512820512820513
GO:BP GO:1903707 negative regulation of hemopoiesis 0.00580825158953954 109 35 3 0.0857142857142857 0.0275229357798165
GO:BP GO:0045927 positive regulation of growth 0.00582467960546845 274 53 5 0.0943396226415094 0.0182481751824818
GO:BP GO:0003231 cardiac ventricle development 0.00585804769850148 120 120 5 0.0416666666666667 0.0416666666666667
GO:BP GO:0045765 regulation of angiogenesis 0.0058750830009502 358 41 5 0.121951219512195 0.0139664804469274
GO:BP GO:0045494 photoreceptor cell maintenance 0.0058750830009502 45 85 3 0.0352941176470588 0.0666666666666667
GO:BP GO:0050801 ion homeostasis 0.0058750830009502 808 110 13 0.118181818181818 0.0160891089108911
GO:BP GO:0032870 cellular response to hormone stimulus 0.00590536764750631 645 89 10 0.112359550561798 0.0155038759689922
GO:BP GO:0032989 cellular component morphogenesis 0.0059622141411724 791 99 12 0.121212121212121 0.0151706700379267
GO:BP GO:0016358 dendrite development 0.00599237730836708 243 89 6 0.0674157303370786 0.0246913580246914
GO:BP GO:0060070 canonical Wnt signaling pathway 0.00602727009855836 345 86 7 0.0813953488372093 0.0202898550724638
GO:BP GO:0014911 positive regulation of smooth muscle cell migration 0.00604873682376455 49 79 3 0.0379746835443038 0.0612244897959184
GO:BP GO:0042063 gliogenesis 0.00605637403175982 308 124 8 0.0645161290322581 0.025974025974026
GO:BP GO:1901342 regulation of vasculature development 0.00612608210151281 364 41 5 0.121951219512195 0.0137362637362637
GO:BP GO:0051336 regulation of hydrolase activity 0.00621774654849455 1321 104 17 0.163461538461538 0.0128690386071158
GO:BP GO:0007548 sex differentiation 0.00624709251895301 275 140 8 0.0571428571428571 0.0290909090909091
GO:BP GO:0051049 regulation of transport 0.0065991108724789 1809 71 16 0.225352112676056 0.00884466556108347
GO:BP GO:0062014 negative regulation of small molecule metabolic process 0.00661524406401313 105 84 4 0.0476190476190476 0.0380952380952381
GO:BP GO:0032526 response to retinoic acid 0.00667950057641591 110 37 3 0.0810810810810811 0.0272727272727273
GO:BP GO:0001659 temperature homeostasis 0.00691921426223026 174 24 3 0.125 0.0172413793103448
GO:BP GO:0016485 protein processing 0.00692208432276633 235 18 3 0.166666666666667 0.0127659574468085
GO:BP GO:0045666 positive regulation of neuron differentiation 0.0069891049900132 101 89 4 0.0449438202247191 0.0396039603960396
GO:BP GO:0070374 positive regulation of ERK1 and ERK2 cascade 0.00699024268351823 215 71 5 0.0704225352112676 0.0232558139534884
GO:BP GO:0090303 positive regulation of wound healing 0.00699024268351823 60 69 3 0.0434782608695652 0.05
GO:BP GO:0060191 regulation of lipase activity 0.00741149449134587 101 42 3 0.0714285714285714 0.0297029702970297
GO:BP GO:0008285 negative regulation of cell population proliferation 0.00742449540134568 790 89 11 0.123595505617978 0.0139240506329114
GO:BP GO:0051253 negative regulation of RNA metabolic process 0.00742449540134568 1445 89 16 0.179775280898876 0.0110726643598616
GO:BP GO:0050773 regulation of dendrite development 0.00742449540134568 103 89 4 0.0449438202247191 0.0388349514563107
GO:BP GO:0021510 spinal cord development 0.0074537795805694 104 41 3 0.0731707317073171 0.0288461538461538
GO:BP GO:0043549 regulation of kinase activity 0.00758774521819344 921 77 11 0.142857142857143 0.011943539630836
GO:BP GO:1990778 protein localization to cell periphery 0.00759940948639751 338 28 4 0.142857142857143 0.0118343195266272
GO:BP GO:0000165 MAPK cascade 0.00759940948639751 935 99 13 0.131313131313131 0.013903743315508
GO:BP GO:0055082 cellular chemical homeostasis 0.00773922251216565 841 110 13 0.118181818181818 0.0154577883472057
GO:BP GO:2001239 regulation of extrinsic apoptotic signaling pathway in absence of ligand 0.00779836727227337 44 99 3 0.0303030303030303 0.0681818181818182
GO:BP GO:0034331 cell junction maintenance 0.0078980055201364 36 122 3 0.0245901639344262 0.0833333333333333
GO:BP GO:0070371 ERK1 and ERK2 cascade 0.00793520091246284 329 71 6 0.0845070422535211 0.0182370820668693
GO:BP GO:0010595 positive regulation of endothelial cell migration 0.00793996812644568 138 32 3 0.09375 0.0217391304347826
GO:BP GO:0050731 positive regulation of peptidyl-tyrosine phosphorylation 0.00802955054389196 198 48 4 0.0833333333333333 0.0202020202020202
GO:BP GO:0007368 determination of left/right symmetry 0.00841357023700546 126 76 4 0.0526315789473684 0.0317460317460317
GO:BP GO:0043434 response to peptide hormone 0.00845390688905997 462 89 8 0.0898876404494382 0.0173160173160173
GO:BP GO:0045859 regulation of protein kinase activity 0.0085131074680265 809 89 11 0.123595505617978 0.0135970333745365
GO:BP GO:0033077 T cell differentiation in thymus 0.0085131074680265 76 127 4 0.031496062992126 0.0526315789473684
GO:BP GO:0003179 heart valve morphogenesis 0.00852482758780359 54 84 3 0.0357142857142857 0.0555555555555556
GO:BP GO:0010718 positive regulation of epithelial to mesenchymal transition 0.00852482758780359 51 89 3 0.0337078651685393 0.0588235294117647
GO:BP GO:0006081 cellular aldehyde metabolic process 0.0085673103095714 64 71 3 0.0422535211267606 0.046875
GO:BP GO:0001959 regulation of cytokine-mediated signaling pathway 0.00864441049124514 184 53 4 0.0754716981132075 0.0217391304347826
GO:BP GO:0099536 synaptic signaling 0.00871326248798033 738 70 9 0.128571428571429 0.0121951219512195
GO:BP GO:1903530 regulation of secretion by cell 0.00871326248798033 588 71 8 0.112676056338028 0.0136054421768707
GO:BP GO:0048709 oligodendrocyte differentiation 0.00871326248798033 102 45 3 0.0666666666666667 0.0294117647058824
GO:BP GO:0051128 regulation of cellular component organization 0.00877671158932977 2412 93 23 0.247311827956989 0.00953565505804312
GO:BP GO:0002376 immune system process 0.00885990182579841 3278 58 20 0.344827586206897 0.0061012812690665
GO:BP GO:0007219 Notch signaling pathway 0.00891589964831271 193 124 6 0.0483870967741935 0.0310880829015544
GO:BP GO:0006694 steroid biosynthetic process 0.00905466060193071 196 84 5 0.0595238095238095 0.0255102040816327
GO:BP GO:0001666 response to hypoxia 0.0091065165558522 367 89 7 0.0786516853932584 0.0190735694822888
GO:BP GO:0061844 antimicrobial humoral immune response mediated by antimicrobial peptide 0.00921187790539124 81 58 3 0.0517241379310345 0.037037037037037
GO:BP GO:0060255 regulation of macromolecule metabolic process 0.00926306409211176 6603 36 22 0.611111111111111 0.00333181887021051
GO:BP GO:0061564 axon development 0.00929473261870515 523 99 9 0.0909090909090909 0.017208413001912
GO:BP GO:0006629 lipid metabolic process 0.00943326827388722 1457 91 16 0.175824175824176 0.0109814687714482
GO:BP GO:0031324 negative regulation of cellular metabolic process 0.00986846164534576 2719 84 23 0.273809523809524 0.00845899227657227
GO:BP GO:0055065 metal ion homeostasis 0.0098753832988241 667 110 11 0.1 0.0164917541229385
GO:BP GO:0009954 proximal/distal pattern formation 0.0100030738784213 35 140 3 0.0214285714285714 0.0857142857142857
GO:BP GO:0019222 regulation of metabolic process 0.0102245949280815 7148 34 22 0.647058823529412 0.00307778399552322
GO:BP GO:0060135 maternal process involved in female pregnancy 0.0103272012579007 65 76 3 0.0394736842105263 0.0461538461538462
GO:BP GO:0030003 cellular cation homeostasis 0.0104586217273529 673 110 11 0.1 0.0163447251114413
GO:BP GO:0060759 regulation of response to cytokine stimulus 0.0104937620851739 197 53 4 0.0754716981132075 0.0203045685279188
GO:BP GO:0040014 regulation of multicellular organism growth 0.0105847099214649 65 77 3 0.038961038961039 0.0461538461538462
GO:BP GO:0016310 phosphorylation 0.0108016459711547 2138 94 21 0.223404255319149 0.009822263797942
GO:BP GO:0036293 response to decreased oxygen levels 0.0108128983259172 382 89 7 0.0786516853932584 0.0183246073298429
GO:BP GO:0051248 negative regulation of protein metabolic process 0.0108770038965783 1151 66 11 0.166666666666667 0.00955690703735882
GO:BP GO:0010662 regulation of striated muscle cell apoptotic process 0.0113052526283711 58 89 3 0.0337078651685393 0.0517241379310345
GO:BP GO:0046579 positive regulation of Ras protein signal transduction 0.011369310431206 75 69 3 0.0434782608695652 0.04
GO:BP GO:0006873 cellular ion homeostasis 0.0116555785029578 687 110 11 0.1 0.0160116448326055
GO:BP GO:0044093 positive regulation of molecular function 0.0117483759049853 1771 99 19 0.191919191919192 0.0107284020327499
GO:BP GO:0006939 smooth muscle contraction 0.0117741391089647 110 99 4 0.0404040404040404 0.0363636363636364
GO:BP GO:0003170 heart valve development 0.0117741391089647 63 84 3 0.0357142857142857 0.0476190476190476
GO:BP GO:0006029 proteoglycan metabolic process 0.0118465206449773 89 123 4 0.032520325203252 0.0449438202247191
GO:BP GO:1901890 positive regulation of cell junction assembly 0.0118898599810935 97 113 4 0.0353982300884956 0.0412371134020619
GO:BP GO:0046903 secretion 0.0119892791642609 1501 45 10 0.222222222222222 0.00666222518321119
GO:BP GO:0046890 regulation of lipid biosynthetic process 0.0120836422639625 215 84 5 0.0595238095238095 0.0232558139534884
GO:BP GO:0060284 regulation of cell development 0.0121181536261007 502 89 8 0.0898876404494382 0.0159362549800797
GO:BP GO:0030510 regulation of BMP signaling pathway 0.0121181536261007 96 56 3 0.0535714285714286 0.03125
GO:BP GO:0021537 telencephalon development 0.012241685671466 256 71 5 0.0704225352112676 0.01953125
GO:BP GO:0045934 negative regulation of nucleobase-containing compound metabolic process 0.0123362837073116 1548 89 16 0.179775280898876 0.0103359173126615
GO:BP GO:0010658 striated muscle cell apoptotic process 0.0124027093050621 61 89 3 0.0337078651685393 0.0491803278688525
GO:BP GO:0048812 neuron projection morphogenesis 0.0125185068697518 664 99 10 0.101010101010101 0.0150602409638554
GO:BP GO:0008584 male gonad development 0.0127093356271485 142 79 4 0.0506329113924051 0.028169014084507
GO:BP GO:0046546 development of primary male sexual characteristics 0.0128169675793607 143 79 4 0.0506329113924051 0.027972027972028
GO:BP GO:0007568 aging 0.0128518561147592 329 81 6 0.0740740740740741 0.0182370820668693
GO:BP GO:1902930 regulation of alcohol biosynthetic process 0.0128520124865848 78 71 3 0.0422535211267606 0.0384615384615385
GO:BP GO:0030111 regulation of Wnt signaling pathway 0.0128877767430599 376 120 8 0.0666666666666667 0.0212765957446809
GO:BP GO:0031327 negative regulation of cellular biosynthetic process 0.0129272837675352 1707 89 17 0.191011235955056 0.00995899238429994
GO:BP GO:0007498 mesoderm development 0.0129272837675352 132 140 5 0.0357142857142857 0.0378787878787879
GO:BP GO:0007224 smoothened signaling pathway 0.0129715114067114 139 82 4 0.0487804878048781 0.0287769784172662
GO:BP GO:0048813 dendrite morphogenesis 0.0130804922963248 145 128 5 0.0390625 0.0344827586206897
GO:BP GO:0010975 regulation of neuron projection development 0.013161068079701 451 101 8 0.0792079207920792 0.0177383592017738
GO:BP GO:1903131 mononuclear cell differentiation 0.0132242122291441 430 63 6 0.0952380952380952 0.013953488372093
GO:BP GO:0051057 positive regulation of small GTPase mediated signal transduction 0.0133182640023709 82 69 3 0.0434782608695652 0.0365853658536585
GO:BP GO:0010921 regulation of phosphatase activity 0.0133964691959906 180 104 5 0.0480769230769231 0.0277777777777778
GO:BP GO:0042310 vasoconstriction 0.0136791367719534 83 69 3 0.0434782608695652 0.036144578313253
GO:BP GO:0010634 positive regulation of epithelial cell migration 0.0136984116455731 181 32 3 0.09375 0.0165745856353591
GO:BP GO:0120039 plasma membrane bounded cell projection morphogenesis 0.0136984116455731 678 99 10 0.101010101010101 0.0147492625368732
GO:BP GO:0070482 response to oxygen levels 0.0137199724767339 408 89 7 0.0786516853932584 0.017156862745098
GO:BP GO:0099054 presynapse assembly 0.0137389174185685 51 113 3 0.0265486725663717 0.0588235294117647
GO:BP GO:0048858 cell projection morphogenesis 0.0141065140885197 682 99 10 0.101010101010101 0.0146627565982405
GO:BP GO:0051338 regulation of transferase activity 0.0143878200234577 1035 77 11 0.142857142857143 0.0106280193236715
GO:BP GO:0044092 negative regulation of molecular function 0.0145065211711355 1219 48 9 0.1875 0.007383100902379
GO:BP GO:0090130 tissue migration 0.0145460303708662 379 32 4 0.125 0.0105540897097625
GO:BP GO:0044344 cellular response to fibroblast growth factor stimulus 0.0145460303708662 147 81 4 0.0493827160493827 0.0272108843537415
GO:BP GO:0051235 maintenance of location 0.0145460303708662 337 109 7 0.0642201834862385 0.0207715133531157
GO:BP GO:0009100 glycoprotein metabolic process 0.0145838456252336 424 134 9 0.0671641791044776 0.0212264150943396
GO:BP GO:1901215 negative regulation of neuron death 0.0147011431999614 213 130 6 0.0461538461538462 0.028169014084507
GO:BP GO:0072676 lymphocyte migration 0.0147011431999614 117 51 3 0.0588235294117647 0.0256410256410256
GO:BP GO:0045600 positive regulation of fat cell differentiation 0.0147011431999614 67 89 3 0.0337078651685393 0.0447761194029851
GO:BP GO:0045861 negative regulation of proteolysis 0.0147011431999614 359 34 4 0.117647058823529 0.011142061281337
GO:BP GO:0051172 negative regulation of nitrogen compound metabolic process 0.0147644894628552 2518 89 22 0.247191011235955 0.00873709293089754
GO:BP GO:0043524 negative regulation of neuron apoptotic process 0.0149881325530894 150 130 5 0.0384615384615385 0.0333333333333333
GO:BP GO:0051048 negative regulation of secretion 0.0149920742654288 176 69 4 0.0579710144927536 0.0227272727272727
GO:BP GO:0007411 axon guidance 0.0151050961790751 283 99 6 0.0606060606060606 0.0212014134275618
GO:BP GO:0098742 cell-cell adhesion via plasma-membrane adhesion molecules 0.0151616309140204 277 71 5 0.0704225352112676 0.0180505415162455
GO:BP GO:0099172 presynapse organization 0.015217729253635 54 113 3 0.0265486725663717 0.0555555555555556
GO:BP GO:0097485 neuron projection guidance 0.015272042418566 284 99 6 0.0606060606060606 0.0211267605633803
GO:BP GO:0048609 multicellular organismal reproductive process 0.0154396498602844 845 8 3 0.375 0.00355029585798817
GO:BP GO:0032755 positive regulation of interleukin-6 production 0.0154439436360098 89 69 3 0.0434782608695652 0.0337078651685393
GO:BP GO:1904892 regulation of receptor signaling pathway via STAT 0.015479585341436 118 104 4 0.0384615384615385 0.0338983050847458
GO:BP GO:0048872 homeostasis of number of cells 0.0155704130231866 261 76 5 0.0657894736842105 0.0191570881226054
GO:BP GO:0010035 response to inorganic substance 0.0155907329344475 575 139 11 0.079136690647482 0.0191304347826087
GO:BP GO:0032990 cell part morphogenesis 0.0156989651222038 699 99 10 0.101010101010101 0.0143061516452074
GO:BP GO:0071774 response to fibroblast growth factor 0.0158583980022824 153 81 4 0.0493827160493827 0.0261437908496732
GO:BP GO:0060560 developmental growth involved in morphogenesis 0.0160179364283701 236 53 4 0.0754716981132075 0.0169491525423729
GO:BP GO:0032504 multicellular organism reproduction 0.0162277249820318 865 8 3 0.375 0.00346820809248555
GO:BP GO:0080090 regulation of primary metabolic process 0.0163151865589735 6053 36 20 0.555555555555556 0.00330414670411366
GO:BP GO:0090066 regulation of anatomical structure size 0.0164191042932365 518 93 8 0.0860215053763441 0.0154440154440154
GO:BP GO:1905952 regulation of lipid localization 0.0166996425636169 201 32 3 0.09375 0.0149253731343284
GO:BP GO:0002088 lens development in camera-type eye 0.0167060290942794 84 76 3 0.0394736842105263 0.0357142857142857
GO:BP GO:0045444 fat cell differentiation 0.0170466643679574 229 89 5 0.0561797752808989 0.0218340611353712
GO:BP GO:1905114 cell surface receptor signaling pathway involved in cell-cell signaling 0.0170861356005431 636 128 11 0.0859375 0.0172955974842767
GO:BP GO:2000113 negative regulation of cellular macromolecule biosynthetic process 0.0170861356005431 1628 89 16 0.179775280898876 0.00982800982800983
GO:BP GO:0097190 apoptotic signaling pathway 0.0173528500771126 600 99 9 0.0909090909090909 0.015
GO:BP GO:0046661 male sex differentiation 0.0174399054879776 163 79 4 0.0506329113924051 0.0245398773006135
GO:BP GO:0007631 feeding behavior 0.0174657362611668 99 130 4 0.0307692307692308 0.0404040404040404
GO:BP GO:0048667 cell morphogenesis involved in neuron differentiation 0.0175239897714392 602 99 9 0.0909090909090909 0.0149501661129568
GO:BP GO:0001667 ameboidal-type cell migration 0.0175239897714392 494 99 8 0.0808080808080808 0.0161943319838057
GO:BP GO:1901652 response to peptide 0.0175483737174854 551 89 8 0.0898876404494382 0.014519056261343
GO:BP GO:0010558 negative regulation of macromolecule biosynthetic process 0.0178835087098797 1639 89 16 0.179775280898876 0.00976205003050641
GO:BP GO:0120036 plasma membrane bounded cell projection organization 0.0179490200585856 1569 101 17 0.168316831683168 0.0108349267049076
GO:BP GO:0055080 cation homeostasis 0.0180410247904972 750 110 11 0.1 0.0146666666666667
GO:BP GO:0003151 outflow tract morphogenesis 0.0182878684880502 75 89 3 0.0337078651685393 0.04
GO:BP GO:0033993 response to lipid 0.0182878684880502 918 8 3 0.375 0.00326797385620915
GO:BP GO:0002688 regulation of leukocyte chemotaxis 0.0185279429465732 120 56 3 0.0535714285714286 0.025
GO:BP GO:0001895 retina homeostasis 0.0185373470217745 79 85 3 0.0352941176470588 0.0379746835443038
GO:BP GO:0014910 regulation of smooth muscle cell migration 0.0185373470217745 85 79 3 0.0379746835443038 0.0352941176470588
GO:BP GO:0099637 neurotransmitter receptor transport 0.0186339557965371 49 138 3 0.0217391304347826 0.0612244897959184
GO:BP GO:0007369 gastrulation 0.0189473114380691 185 37 3 0.0810810810810811 0.0162162162162162
GO:BP GO:0008589 regulation of smoothened signaling pathway 0.0189767775916037 83 82 3 0.0365853658536585 0.036144578313253
GO:BP GO:0019725 cellular homeostasis 0.0193182442290638 981 110 13 0.118181818181818 0.0132517838939857
GO:BP GO:0045576 mast cell activation 0.0193936008606655 62 111 3 0.027027027027027 0.0483870967741935
GO:BP GO:0098771 inorganic ion homeostasis 0.0194299382776013 761 110 11 0.1 0.0144546649145861
GO:BP GO:0009892 negative regulation of metabolic process 0.0196896880575822 3479 84 26 0.30952380952381 0.00747341189997126
GO:BP GO:0050727 regulation of inflammatory response 0.0197017836206403 381 36 4 0.111111111111111 0.010498687664042
GO:BP GO:0035556 intracellular signal transduction 0.0197767186172093 2772 99 25 0.252525252525253 0.00901875901875902
GO:BP GO:0044070 regulation of anion transport 0.0198164989959586 896 69 9 0.130434782608696 0.0100446428571429
GO:BP GO:0043086 negative regulation of catalytic activity 0.0198830834555554 851 48 7 0.145833333333333 0.0082256169212691
GO:BP GO:0051223 regulation of protein transport 0.0199999876863185 586 69 7 0.101449275362319 0.0119453924914676
GO:BP GO:0038034 signal transduction in absence of ligand 0.0202187222969098 71 99 3 0.0303030303030303 0.0422535211267606
GO:BP GO:0007200 phospholipase C-activating G protein-coupled receptor signaling pathway 0.0202187222969098 102 69 3 0.0434782608695652 0.0294117647058824
GO:BP GO:0097192 extrinsic apoptotic signaling pathway in absence of ligand 0.0202187222969098 71 99 3 0.0303030303030303 0.0422535211267606
GO:BP GO:0043407 negative regulation of MAP kinase activity 0.0206873039193375 80 89 3 0.0337078651685393 0.0375
GO:BP GO:0098869 cellular oxidant detoxification 0.0211446996610983 100 139 4 0.0287769784172662 0.04
GO:BP GO:0048878 chemical homeostasis 0.0211958582803877 1229 19 5 0.263157894736842 0.00406834825061025
GO:BP GO:0010810 regulation of cell-substrate adhesion 0.0211958582803877 222 63 4 0.0634920634920635 0.018018018018018
GO:BP GO:0030030 cell projection organization 0.0212463431283816 1609 101 17 0.168316831683168 0.0105655686761964
GO:BP GO:0034440 lipid oxidation 0.0212463431283816 113 64 3 0.046875 0.0265486725663717
GO:BP GO:0008406 gonad development 0.0212463431283816 221 140 6 0.0428571428571429 0.0271493212669683
GO:BP GO:0016043 cellular component organization 0.0212737093893714 6566 101 49 0.485148514851485 0.00746268656716418
GO:BP GO:0002687 positive regulation of leukocyte migration 0.0213643959920653 137 53 3 0.0566037735849057 0.0218978102189781
GO:BP GO:0051047 positive regulation of secretion 0.021376145786835 314 99 6 0.0606060606060606 0.0191082802547771
GO:BP GO:0030162 regulation of proteolysis 0.0215320206202429 752 69 8 0.115942028985507 0.0106382978723404
GO:BP GO:0042493 response to drug 0.0218612602381561 396 19 3 0.157894736842105 0.00757575757575758
GO:BP GO:1903706 regulation of hemopoiesis 0.0219926106822162 424 53 5 0.0943396226415094 0.0117924528301887
GO:BP GO:0051346 negative regulation of hydrolase activity 0.0220946381826422 470 48 5 0.104166666666667 0.0106382978723404
GO:BP GO:0001892 embryonic placenta development 0.0221187067181592 83 89 3 0.0337078651685393 0.036144578313253
GO:BP GO:0051208 sequestering of calcium ion 0.0221187067181592 130 109 4 0.036697247706422 0.0307692307692308
GO:BP GO:0031323 regulation of cellular metabolic process 0.0221187067181592 6269 36 20 0.555555555555556 0.00319030148349019
GO:BP GO:0006936 muscle contraction 0.0227566176236728 364 114 7 0.0614035087719298 0.0192307692307692
GO:BP GO:0002521 leukocyte differentiation 0.0227733280150854 550 76 7 0.0921052631578947 0.0127272727272727
GO:BP GO:0090288 negative regulation of cellular response to growth factor stimulus 0.0227954278301242 119 63 3 0.0476190476190476 0.0252100840336134
GO:BP GO:0035303 regulation of dephosphorylation 0.0229120599365836 217 104 5 0.0480769230769231 0.0230414746543779
GO:BP GO:0009628 response to abiotic stimulus 0.0231727301001673 1261 89 13 0.146067415730337 0.0103092783505155
GO:BP GO:0045137 development of primary sexual characteristics 0.0232205238255753 227 140 6 0.0428571428571429 0.026431718061674
GO:BP GO:0070201 regulation of establishment of protein localization 0.0232532340152363 611 69 7 0.101449275362319 0.0114566284779051
GO:BP GO:0016055 Wnt signaling pathway 0.0235199911171708 529 120 9 0.075 0.0170132325141777
GO:BP GO:0030166 proteoglycan biosynthetic process 0.0235513636195241 62 123 3 0.024390243902439 0.0483870967741935
GO:BP GO:0198738 cell-cell signaling by wnt 0.0238184376062753 531 120 9 0.075 0.0169491525423729
GO:BP GO:0010594 regulation of endothelial cell migration 0.0241734909474967 244 32 3 0.09375 0.0122950819672131
GO:BP GO:0006606 protein import into nucleus 0.02418527619345 152 51 3 0.0588235294117647 0.0197368421052632
GO:BP GO:0090087 regulation of peptide transport 0.0241864519340787 618 69 7 0.101449275362319 0.0113268608414239
GO:BP GO:0051353 positive regulation of oxidoreductase activity 0.024329497927896 56 139 3 0.0215827338129496 0.0535714285714286
GO:BP GO:0010811 positive regulation of cell-substrate adhesion 0.0245415644488263 124 63 3 0.0476190476190476 0.0241935483870968
GO:BP GO:0050767 regulation of neurogenesis 0.024624956141652 366 89 6 0.0674157303370786 0.0163934426229508
GO:BP GO:0055017 cardiac muscle tissue growth 0.024624956141652 103 76 3 0.0394736842105263 0.029126213592233
GO:BP GO:0051402 neuron apoptotic process 0.0247885540796275 250 130 6 0.0461538461538462 0.024
GO:BP GO:0008610 lipid biosynthetic process 0.0250410125912902 740 21 4 0.19047619047619 0.00540540540540541
GO:BP GO:0032642 regulation of chemokine production 0.025111191615854 94 84 3 0.0357142857142857 0.0319148936170213
GO:BP GO:0031667 response to nutrient levels 0.0251372739516758 482 89 7 0.0786516853932584 0.0145228215767635
GO:BP GO:0007565 female pregnancy 0.0252250051845624 198 76 4 0.0526315789473684 0.0202020202020202
GO:BP GO:0007610 behavior 0.0252752555771596 586 130 10 0.0769230769230769 0.0170648464163823
GO:BP GO:0001952 regulation of cell-matrix adhesion 0.0256865253525635 127 63 3 0.0476190476190476 0.0236220472440945
GO:BP GO:0021782 glial cell development 0.0257408301060352 122 124 4 0.032258064516129 0.0327868852459016
GO:BP GO:0009913 epidermal cell differentiation 0.0257921465407061 365 42 4 0.0952380952380952 0.010958904109589
GO:BP GO:1902105 regulation of leukocyte differentiation 0.0258224517665362 288 53 4 0.0754716981132075 0.0138888888888889
GO:BP GO:0043954 cellular component maintenance 0.0259927737728816 66 122 3 0.0245901639344262 0.0454545454545455
GO:BP GO:0034614 cellular response to reactive oxygen species 0.026071452992969 170 139 5 0.0359712230215827 0.0294117647058824
GO:BP GO:0097306 cellular response to alcohol 0.0262004343069838 93 87 3 0.0344827586206897 0.032258064516129
GO:BP GO:0003281 ventricular septum development 0.0265449189879973 68 120 3 0.025 0.0441176470588235
GO:BP GO:0030307 positive regulation of cell growth 0.0266989806602858 171 48 3 0.0625 0.0175438596491228
GO:BP GO:0000122 negative regulation of transcription by RNA polymerase II 0.0268910786094275 901 18 4 0.222222222222222 0.00443951165371809
GO:BP GO:0000902 cell morphogenesis 0.027347365090803 1037 111 13 0.117117117117117 0.0125361620057859
GO:BP GO:0052547 regulation of peptidase activity 0.0275694113884314 467 34 4 0.117647058823529 0.00856531049250535
GO:BP GO:0010660 regulation of muscle cell apoptotic process 0.0277833495353567 94 89 3 0.0337078651685393 0.0319148936170213
GO:BP GO:1990748 cellular detoxification 0.0279362227528818 113 139 4 0.0287769784172662 0.0353982300884956
GO:BP GO:0060419 heart growth 0.0282130088606707 111 76 3 0.0394736842105263 0.027027027027027
GO:BP GO:0022412 cellular process involved in reproduction in multicellular organism 0.0282130088606707 366 67 5 0.0746268656716418 0.0136612021857923
GO:BP GO:0032602 chemokine production 0.0285137129567052 101 84 3 0.0357142857142857 0.0297029702970297
GO:BP GO:0032940 secretion by cell 0.0285560438297863 1364 124 17 0.137096774193548 0.0124633431085044
GO:BP GO:0071695 anatomical structure maturation 0.0285560438297863 224 71 4 0.0563380281690141 0.0178571428571429
GO:BP GO:0120254 olefinic compound metabolic process 0.0292058586789441 121 71 3 0.0422535211267606 0.0247933884297521
GO:BP GO:0001819 positive regulation of cytokine production 0.029284348285669 452 36 4 0.111111111111111 0.00884955752212389
GO:BP GO:0071692 protein localization to extracellular region 0.029485880261154 392 88 6 0.0681818181818182 0.0153061224489796
GO:BP GO:0090090 negative regulation of canonical Wnt signaling pathway 0.0294970850511974 187 86 4 0.0465116279069767 0.0213903743315508
GO:BP GO:0099537 trans-synaptic signaling 0.0298648335523336 713 128 11 0.0859375 0.0154277699859748
GO:BP GO:0000904 cell morphogenesis involved in differentiation 0.0299243820888139 749 106 10 0.0943396226415094 0.0133511348464619
GO:BP GO:0007584 response to nutrient 0.0299932359472777 182 89 4 0.0449438202247191 0.021978021978022
GO:BP GO:0010657 muscle cell apoptotic process 0.0301017946186998 98 89 3 0.0337078651685393 0.0306122448979592
GO:BP GO:0051170 import into nucleus 0.0302500369254375 172 51 3 0.0588235294117647 0.0174418604651163
GO:BP GO:0010721 negative regulation of cell development 0.0304159254698336 183 89 4 0.0449438202247191 0.0218579234972678
GO:BP GO:0006796 phosphate-containing compound metabolic process 0.0310396607572226 3087 94 25 0.265957446808511 0.00809847748623259
GO:BP GO:0051341 regulation of oxidoreductase activity 0.0311384407739145 118 139 4 0.0287769784172662 0.0338983050847458
GO:BP GO:0009991 response to extracellular stimulus 0.0311437449050599 512 89 7 0.0786516853932584 0.013671875
GO:BP GO:0051704 multi-organism process 0.0317027403339624 1135 32 6 0.1875 0.0052863436123348
GO:BP GO:0007162 negative regulation of cell adhesion 0.0320931779805694 304 84 5 0.0595238095238095 0.0164473684210526
GO:BP GO:0010466 negative regulation of peptidase activity 0.0320931779805694 267 34 3 0.0882352941176471 0.0112359550561798
GO:BP GO:0032269 negative regulation of cellular protein metabolic process 0.0322322818158759 1082 9 3 0.333333333333333 0.00277264325323475
GO:BP GO:0010976 positive regulation of neuron projection development 0.0323892987507306 165 101 4 0.0396039603960396 0.0242424242424242
GO:BP GO:0071840 cellular component organization or biogenesis 0.0324767334529745 6760 101 49 0.485148514851485 0.00724852071005917
GO:BP GO:0097237 cellular response to toxic substance 0.0324767334529745 120 139 4 0.0287769784172662 0.0333333333333333
GO:BP GO:0060828 regulation of canonical Wnt signaling pathway 0.0324767334529745 298 86 5 0.0581395348837209 0.0167785234899329
GO:BP GO:0030534 adult behavior 0.032936302400683 131 128 4 0.03125 0.0305343511450382
GO:BP GO:0043542 endothelial cell migration 0.0334842739069449 290 32 3 0.09375 0.0103448275862069
GO:BP GO:0006793 phosphorus metabolic process 0.0336202742818056 3114 94 25 0.265957446808511 0.00802825947334618
GO:BP GO:0001764 neuron migration 0.0339576821092252 157 59 3 0.0508474576271186 0.0191082802547771
GO:BP GO:0006801 superoxide metabolic process 0.0342223433165711 67 139 3 0.0215827338129496 0.0447761194029851
GO:BP GO:0051224 negative regulation of protein transport 0.0342303600449817 135 69 3 0.0434782608695652 0.0222222222222222
GO:BP GO:0071375 cellular response to peptide hormone stimulus 0.0342868914979724 340 77 5 0.0649350649350649 0.0147058823529412
GO:BP GO:0044706 multi-multicellular organism process 0.0350305939795822 227 76 4 0.0526315789473684 0.0176211453744493
GO:BP GO:0030258 lipid modification 0.0352501667986847 271 64 4 0.0625 0.014760147601476
GO:BP GO:0007409 axonogenesis 0.0358601795952546 478 99 7 0.0707070707070707 0.0146443514644351
GO:BP GO:0051129 negative regulation of cellular component organization 0.0359692749767368 759 93 9 0.0967741935483871 0.0118577075098814
GO:BP GO:0006970 response to osmotic stress 0.0361675889460132 84 114 3 0.0263157894736842 0.0357142857142857
GO:BP GO:1904950 negative regulation of establishment of protein localization 0.0362214544897032 139 69 3 0.0434782608695652 0.0215827338129496
GO:BP GO:0070997 neuron death 0.0367559740346731 365 130 7 0.0538461538461538 0.0191780821917808
GO:BP GO:0140352 export from cell 0.0370173332379671 1418 124 17 0.137096774193548 0.0119887165021157
GO:BP GO:0010632 regulation of epithelial cell migration 0.0370173332379671 306 32 3 0.09375 0.00980392156862745
GO:BP GO:0045834 positive regulation of lipid metabolic process 0.037395419543099 155 63 3 0.0476190476190476 0.0193548387096774
GO:BP GO:0008593 regulation of Notch signaling pathway 0.0377195659080403 110 89 3 0.0337078651685393 0.0272727272727273
GO:BP GO:0007188 adenylate cyclase-modulating G protein-coupled receptor signaling pathway 0.0384297950832319 234 116 5 0.0431034482758621 0.0213675213675214
GO:BP GO:0043087 regulation of GTPase activity 0.0386214123533674 493 98 7 0.0714285714285714 0.0141987829614604
GO:BP GO:0007179 transforming growth factor beta receptor signaling pathway 0.0393043223392432 206 88 4 0.0454545454545455 0.0194174757281553
GO:BP GO:0072657 protein localization to membrane 0.0396319942589774 665 28 4 0.142857142857143 0.00601503759398496
GO:BP GO:0071396 cellular response to lipid 0.0397455770137429 578 18 3 0.166666666666667 0.00519031141868512
GO:BP GO:0031644 regulation of nervous system process 0.0399911924299369 147 69 3 0.0434782608695652 0.0204081632653061
GO:BP GO:0023061 signal release 0.0407025192680107 496 99 7 0.0707070707070707 0.0141129032258065
GO:BP GO:0098754 detoxification 0.0418206507846407 134 139 4 0.0287769784172662 0.0298507462686567
GO:BP GO:0043523 regulation of neuron apoptotic process 0.0418757456574387 216 130 5 0.0384615384615385 0.0231481481481481
GO:BP GO:0017038 protein import 0.0421079557447549 205 51 3 0.0588235294117647 0.0146341463414634
GO:BP GO:0031032 actomyosin structure organization 0.0421703179633377 199 94 4 0.0425531914893617 0.0201005025125628
GO:BP GO:1903532 positive regulation of secretion by cell 0.0422871846171419 285 99 5 0.0505050505050505 0.0175438596491228
GO:BP GO:0030178 negative regulation of Wnt signaling pathway 0.0423170287295658 218 86 4 0.0465116279069767 0.018348623853211
GO:BP GO:0031099 regeneration 0.0424357463697725 206 51 3 0.0588235294117647 0.0145631067961165
GO:BP GO:0051171 regulation of nitrogen compound metabolic process 0.0425470535388289 5848 36 18 0.5 0.00307797537619699
GO:BP GO:0030902 hindbrain development 0.0430059185896756 152 124 4 0.032258064516129 0.0263157894736842
GO:BP GO:0045785 positive regulation of cell adhesion 0.0431006565424399 437 89 6 0.0674157303370786 0.0137299771167048
GO:BP GO:0051960 regulation of nervous system development 0.043594965146253 443 113 7 0.0619469026548673 0.0158013544018059
GO:BP GO:0046777 protein autophosphorylation 0.0445545582663123 240 45 3 0.0666666666666667 0.0125
GO:BP GO:0097696 receptor signaling pathway via STAT 0.0445545582663123 184 104 4 0.0384615384615385 0.0217391304347826
GO:BP GO:0035264 multicellular organism growth 0.0447752373478685 140 77 3 0.038961038961039 0.0214285714285714
GO:BP GO:0060249 anatomical structure homeostasis 0.0451472851110572 482 105 7 0.0666666666666667 0.0145228215767635
GO:BP GO:0007186 G protein-coupled receptor signaling pathway 0.0459366132662503 1355 94 13 0.138297872340426 0.00959409594095941
GO:BP GO:0003073 regulation of systemic arterial blood pressure 0.0459366132662503 101 108 3 0.0277777777777778 0.0297029702970297
GO:BP GO:0021700 developmental maturation 0.0463324128968032 275 71 4 0.0563380281690141 0.0145454545454545
GO:BP GO:0048771 tissue remodeling 0.046697928626309 186 105 4 0.0380952380952381 0.021505376344086
GO:BP GO:0006952 defense response 0.0468177913449398 1818 71 13 0.183098591549296 0.00715071507150715
GO:BP GO:0032880 regulation of protein localization 0.0472626384985871 922 69 8 0.115942028985507 0.00867678958785249
GO:BP GO:0010923 negative regulation of phosphatase activity 0.047618302010749 107 104 3 0.0288461538461538 0.0280373831775701
GO:BP GO:0060291 long-term synaptic potentiation 0.0476299348946575 87 128 3 0.0234375 0.0344827586206897
GO:BP GO:0008544 epidermis development 0.0476566864074171 475 42 4 0.0952380952380952 0.00842105263157895
GO:BP GO:0051963 regulation of synapse assembly 0.0478850309181259 99 113 3 0.0265486725663717 0.0303030303030303
GO:BP GO:0046165 alcohol biosynthetic process 0.0479797887212703 158 71 3 0.0422535211267606 0.0189873417721519
GO:BP GO:0048588 developmental cell growth 0.0481699754317841 235 48 3 0.0625 0.0127659574468085
GO:BP GO:0001889 liver development 0.0481793447690998 148 76 3 0.0394736842105263 0.0202702702702703
GO:BP GO:0043547 positive regulation of GTPase activity 0.0484328005300273 413 98 6 0.0612244897959184 0.0145278450363196
GO:BP GO:0017015 regulation of transforming growth factor beta receptor signaling pathway 0.0489470705857685 129 88 3 0.0340909090909091 0.0232558139534884
GO:BP GO:0001817 regulation of cytokine production 0.0489578646781989 806 51 6 0.117647058823529 0.00744416873449132
GO:BP GO:0043687 post-translational protein modification 0.0495561608806096 362 83 5 0.0602409638554217 0.0138121546961326
GO:BP GO:0051130 positive regulation of cellular component organization 0.0496762168192624 1153 89 11 0.123595505617978 0.00954032957502168
GO:BP GO:0061008 hepaticobiliary system development 0.049985912494409 151 76 3 0.0394736842105263 0.0198675496688742
GO:CC GO:0005576 extracellular region 4.00429681544982e-06 4567 134 62 0.462686567164179 0.0135756514123057
GO:CC GO:0005615 extracellular space 4.00429681544982e-06 3594 134 53 0.395522388059701 0.0147468002225932
GO:CC GO:0031012 extracellular matrix 4.49884891806835e-06 562 89 15 0.168539325842697 0.0266903914590747
GO:CC GO:0030312 external encapsulating structure 4.49884891806835e-06 563 89 15 0.168539325842697 0.0266429840142096
GO:CC GO:0005788 endoplasmic reticulum lumen 5.6062969197084e-06 307 83 11 0.132530120481928 0.0358306188925081
GO:CC GO:0062023 collagen-containing extracellular matrix 5.6062969197084e-06 421 89 13 0.146067415730337 0.0308788598574822
GO:CC GO:0005783 endoplasmic reticulum 7.3510007655042e-05 1982 65 21 0.323076923076923 0.0105953582240161
GO:CC GO:0071944 cell periphery 7.7530905430921e-05 6169 134 70 0.522388059701492 0.0113470578699951
GO:CC GO:0009986 cell surface 0.000362910593470355 899 95 16 0.168421052631579 0.017797552836485
GO:CC GO:0012505 endomembrane system 0.000364710358139585 4640 70 34 0.485714285714286 0.00732758620689655
GO:CC GO:0005796 Golgi lumen 0.00114308597050663 99 74 5 0.0675675675675676 0.0505050505050505
GO:CC GO:0031594 neuromuscular junction 0.00114308597050663 73 100 5 0.05 0.0684931506849315
GO:CC GO:0030054 cell junction 0.00132585745809533 2105 128 30 0.234375 0.0142517814726841
GO:CC GO:0005794 Golgi apparatus 0.00158409466123371 1623 77 18 0.233766233766234 0.011090573012939
GO:CC GO:0031226 intrinsic component of plasma membrane 0.00217770622298093 1726 130 26 0.2 0.015063731170336
GO:CC GO:0005887 integral component of plasma membrane 0.00248780913445711 1645 130 25 0.192307692307692 0.0151975683890578
GO:CC GO:0005604 basement membrane 0.00694530141783312 97 125 5 0.04 0.0515463917525773
GO:CC GO:0045202 synapse 0.0102874811232814 1349 128 20 0.15625 0.0148257968865827
GO:CC GO:0045177 apical part of cell 0.0109509892112772 431 130 10 0.0769230769230769 0.0232018561484919
GO:CC GO:0005886 plasma membrane 0.0127605254043037 5681 97 44 0.45360824742268 0.00774511529660271
GO:CC GO:0060170 ciliary membrane 0.0200785058425746 75 128 4 0.03125 0.0533333333333333
GO:CC GO:0030666 endocytic vesicle membrane 0.0252819537845208 159 65 4 0.0615384615384615 0.0251572327044025
GO:CC GO:0042383 sarcolemma 0.0257223280768544 140 124 5 0.0403225806451613 0.0357142857142857
GO:CC GO:0005581 collagen trimer 0.0266448954535801 95 54 3 0.0555555555555556 0.0315789473684211
GO:CC GO:0043005 neuron projection 0.0308459950228937 1380 67 12 0.17910447761194 0.00869565217391304
GO:CC GO:0001750 photoreceptor outer segment 0.0314652976488398 90 128 4 0.03125 0.0444444444444444
GO:CC GO:0045121 membrane raft 0.0340545254273876 335 86 6 0.0697674418604651 0.017910447761194
GO:CC GO:0098978 glutamatergic synapse 0.0340545254273876 349 138 8 0.0579710144927536 0.0229226361031519
GO:CC GO:0098857 membrane microdomain 0.0340545254273876 335 86 6 0.0697674418604651 0.017910447761194
GO:CC GO:0016021 integral component of membrane 0.0340545254273876 5711 75 34 0.453333333333333 0.00595342321835055
GO:CC GO:0030659 cytoplasmic vesicle membrane 0.0388345418876744 779 65 8 0.123076923076923 0.0102695763799743
GO:CC GO:0070062 extracellular exosome 0.0415759064874788 2176 83 18 0.216867469879518 0.00827205882352941
GO:CC GO:0012506 vesicle membrane 0.0426099831125273 800 65 8 0.123076923076923 0.01
GO:CC GO:0031224 intrinsic component of membrane 0.0433988204055353 5868 75 34 0.453333333333333 0.00579413769597819
GO:CC GO:0097060 synaptic membrane 0.0499746419343361 384 138 8 0.0579710144927536 0.0208333333333333
GO:MF GO:0048018 receptor ligand activity 2.75739312192793e-09 494 99 19 0.191919191919192 0.0384615384615385
GO:MF GO:0005102 signaling receptor binding 2.75739312192793e-09 1672 134 39 0.291044776119403 0.0233253588516746
GO:MF GO:0030546 signaling receptor activator activity 2.75739312192793e-09 501 99 19 0.191919191919192 0.0379241516966068
GO:MF GO:0030545 receptor regulator activity 7.29410295133799e-09 545 99 19 0.191919191919192 0.0348623853211009
GO:MF GO:0008083 growth factor activity 9.78681277176761e-08 163 99 11 0.111111111111111 0.0674846625766871
GO:MF GO:0070700 BMP receptor binding 2.15498562875799e-07 13 89 5 0.0561797752808989 0.384615384615385
GO:MF GO:0005125 cytokine activity 1.02995957179195e-06 235 89 11 0.123595505617978 0.0468085106382979
GO:MF GO:0070696 transmembrane receptor protein serine/threonine kinase binding 4.07004411508396e-06 23 89 5 0.0561797752808989 0.217391304347826
GO:MF GO:0033612 receptor serine/threonine kinase binding 1.24839268321794e-05 29 89 5 0.0561797752808989 0.172413793103448
GO:MF GO:0001664 G protein-coupled receptor binding 6.57437787235625e-05 292 70 9 0.128571428571429 0.0308219178082192
GO:MF GO:0098772 molecular function regulator 0.000970485433121343 2363 104 29 0.278846153846154 0.0122725349132459
GO:MF GO:0070851 growth factor receptor binding 0.00160233708154009 143 124 7 0.0564516129032258 0.048951048951049
GO:MF GO:0005509 calcium ion binding 0.00177833322378194 721 134 16 0.119402985074627 0.0221914008321775
GO:MF GO:0008201 heparin binding 0.00361143890813476 168 125 7 0.056 0.0416666666666667
GO:MF GO:0015485 cholesterol binding 0.00772008197819495 50 51 3 0.0588235294117647 0.06
GO:MF GO:0032934 sterol binding 0.0115694039620378 60 51 3 0.0588235294117647 0.05
GO:MF GO:0005539 glycosaminoglycan binding 0.0163160247026647 238 89 6 0.0674157303370786 0.0252100840336134
GO:MF GO:1901681 sulfur compound binding 0.0210965660291849 264 89 6 0.0674157303370786 0.0227272727272727
GO:MF GO:0043178 alcohol binding 0.0210965660291849 88 51 3 0.0588235294117647 0.0340909090909091
GO:MF GO:0005126 cytokine receptor binding 0.0210965660291849 275 58 5 0.0862068965517241 0.0181818181818182
GO:MF GO:0005496 steroid binding 0.0269213219477232 100 51 3 0.0588235294117647 0.03
GO:MF GO:0008528 G protein-coupled peptide receptor activity 0.0277218661082611 148 75 4 0.0533333333333333 0.027027027027027
GO:MF GO:0001653 peptide receptor activity 0.0297318401222823 152 75 4 0.0533333333333333 0.0263157894736842
GO:MF GO:0046332 SMAD binding 0.0316648128317772 78 76 3 0.0394736842105263 0.0384615384615385
GO:MF GO:0038023 signaling receptor activity 0.0342775511210519 1458 28 7 0.25 0.00480109739368999
GO:MF GO:0060089 molecular transducer activity 0.0342775511210519 1458 28 7 0.25 0.00480109739368999
GO:MF GO:0016616 oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor 0.0405061657038409 125 109 4 0.036697247706422 0.032
GO:MF GO:0030971 receptor tyrosine kinase binding 0.0416269071493347 72 99 3 0.0303030303030303 0.0416666666666667
GO:MF GO:0004888 transmembrane signaling receptor activity 0.0441681666827598 1269 19 5 0.263157894736842 0.00394011032308905
GO:MF GO:0016614 oxidoreductase activity, acting on CH-OH group of donors 0.0467394620423435 137 109 4 0.036697247706422 0.0291970802919708
GO:MF GO:0005201 extracellular matrix structural constituent 0.0472895589991445 171 88 4 0.0454545454545455 0.0233918128654971
KEGG KEGG:05217 Basal cell carcinoma 0.00267744291398601 63 71 6 0.0845070422535211 0.0952380952380952
KEGG KEGG:05200 Pathways in cancer 0.0032723511937025 529 87 17 0.195402298850575 0.0321361058601134
REAC REAC:R-HSA-186797 Signaling by PDGF 0.00650097339390187 54 30 4 0.133333333333333 0.0740740740740741
REAC REAC:R-HSA-1474244 Extracellular matrix organization 0.0121217869676468 298 106 11 0.10377358490566 0.0369127516778524
REAC REAC:R-HSA-2129379 Molecules associated with elastic fibres 0.0121217869676468 37 89 4 0.0449438202247191 0.108108108108108
REAC REAC:R-HSA-381426 Regulation of Insulin-like Growth Factor (IGF) transport and uptake by Insulin-like Growth Factor Binding Proteins (IGFBPs) 0.0163670347410143 124 83 6 0.072289156626506 0.0483870967741935
REAC REAC:R-HSA-1566948 Elastic fibre formation 0.0172205532336954 44 89 4 0.0449438202247191 0.0909090909090909
REAC REAC:R-HSA-3238698 WNT ligand biogenesis and trafficking 0.0172205532336954 26 65 3 0.0461538461538462 0.115384615384615
REAC REAC:R-HSA-8957275 Post-translational protein phosphorylation 0.0431477178822412 107 83 5 0.0602409638554217 0.0467289719626168
TF TF:M01104_1 Factor: MOVO-B; motif: GNGGGGG; match class: 1 0.0313290539085749 5626 140 65 0.464285714285714 0.0115535015997156
WP WP:WP2839 Hair Follicle Development: Organogenesis - Part 2 of 3 0.011269206171312 33 18 3 0.166666666666667 0.0909090909090909
WP WP:WP3413 NOTCH1 regulation of human endothelial cell calcification 0.011269206171312 18 41 3 0.0731707317073171 0.166666666666667
WP WP:WP4787 Osteoblast differentiation 0.0124543711777697 119 79 7 0.0886075949367089 0.0588235294117647
WP WP:WP2406 Cardiac Progenitor Differentiation 0.0124543711777697 53 45 4 0.0888888888888889 0.0754716981132075
WP WP:WP474 Endochondral Ossification 0.0127309790517094 65 18 3 0.166666666666667 0.0461538461538462
WP WP:WP4808 Endochondral Ossification with Skeletal Dysplasias 0.0127309790517094 65 18 3 0.166666666666667 0.0461538461538462
WP WP:WP4872 MAP3K1 role in promoting and blocking gonadal determination 0.0165840935264335 17 79 3 0.0379746835443038 0.176470588235294
WP WP:WP4239 Epithelial to mesenchymal transition in colorectal cancer 0.0393539744375488 164 84 7 0.0833333333333333 0.0426829268292683
WP WP:WP2895 Differentiation of white and brown adipocyte 0.0395925274266183 25 89 3 0.0337078651685393 0.12
WP WP:WP3612 Photodynamic therapy-induced NFE2L2 (NRF2) survival signaling 0.0395925274266183 23 95 3 0.0315789473684211 0.130434782608696
WP WP:WP4767 FGFR3 signalling in chondrocyte proliferation and terminal differentiation 0.0395925274266183 27 79 3 0.0379746835443038 0.111111111111111

pS17 transcription factor target enrichment of top program genes

TF enrichment of pS17
TFs corrosponding to activation of pS17. (Left) pearson correlation of TF expression and gene expression program activatity in Stromal cells, (right) negative log p-value for enrichment of TF binding sites among top uniqueness weighted genes for the gene program. Blue bars indicate significant TFs meeting the following criteria: FDR<0.1, overlap > 2, Corr. R > 0, permutation based p-value < 0.05.