pP02 program activity among Plasma cells

Activation of pP02
pP02 gene program activation in Plasma cells.
Gene program activation of pP02 by different cell subtypes
pP02 gene program activation among cells of different subtypes (Plasma cells).

pP02 top program genes

Top genes of pP02 program
Bar plots showing the top genes for each gene program, ranked by (left) unique weights, (right) raw weights.

pP02 gene-set enrichment of top program genes (using g-profiler)

GSEA wth gene profiler of pP02
pP02 gene-set enrichment summary using g-profiler webtool.
Source termID Name Padj Tsize Qsize Overlap Precision Recall
CORUM CORUM:6859 HRD1 complex 0.000102186478366212 13 116 6 0.0517241379310345 0.461538461538462
CORUM CORUM:4999 VCP-VIMP-DERL1-DERL2-HRD1-SEL1L complex 0.000375828443028878 6 106 4 0.0377358490566038 0.666666666666667
CORUM CORUM:6131 SELK multiprotein complex 0.00160149883213649 10 106 4 0.0377358490566038 0.4
CORUM CORUM:1199 Oligosaccharyltransferase complex (Stt3A variant) 0.00757452466462478 6 128 3 0.0234375 0.5
CORUM CORUM:1200 Oligosaccharyltransferase complex (Stt3B variant) 0.00857784656094594 7 128 3 0.0234375 0.428571428571429
GO:BP GO:0034976 response to endoplasmic reticulum stress 4.32263477559346e-27 298 116 32 0.275862068965517 0.10738255033557
GO:BP GO:0035966 response to topologically incorrect protein 1.71374770523788e-21 205 108 24 0.222222222222222 0.117073170731707
GO:BP GO:0006986 response to unfolded protein 2.48988190394908e-21 184 108 23 0.212962962962963 0.125
GO:BP GO:0035967 cellular response to topologically incorrect protein 7.0392722730207e-21 168 108 22 0.203703703703704 0.130952380952381
GO:BP GO:0034620 cellular response to unfolded protein 1.27871513878361e-20 149 108 21 0.194444444444444 0.140939597315436
GO:BP GO:0030968 endoplasmic reticulum unfolded protein response 1.48095923286387e-20 128 108 20 0.185185185185185 0.15625
GO:BP GO:0046907 intracellular transport 3.23938847539057e-14 1767 136 49 0.360294117647059 0.0277306168647425
GO:BP GO:0032527 protein exit from endoplasmic reticulum 1.43775405881472e-13 48 127 12 0.094488188976378 0.25
GO:BP GO:0006888 endoplasmic reticulum to Golgi vesicle-mediated transport 2.28818404618692e-13 206 135 19 0.140740740740741 0.0922330097087379
GO:BP GO:0030970 retrograde protein transport, ER to cytosol 2.28818404618692e-13 28 116 10 0.0862068965517241 0.357142857142857
GO:BP GO:1903513 endoplasmic reticulum to cytosol transport 2.28818404618692e-13 28 116 10 0.0862068965517241 0.357142857142857
GO:BP GO:0006886 intracellular protein transport 2.88437998184919e-13 1186 136 39 0.286764705882353 0.0328836424957841
GO:BP GO:0036503 ERAD pathway 7.0576396850552e-13 103 116 14 0.120689655172414 0.135922330097087
GO:BP GO:0071705 nitrogen compound transport 9.32886711853988e-12 2322 136 52 0.382352941176471 0.0223944875107666
GO:BP GO:0015031 protein transport 1.13084941243871e-11 1929 136 47 0.345588235294118 0.024364955935718
GO:BP GO:0045184 establishment of protein localization 1.74431198450071e-11 2035 136 48 0.352941176470588 0.0235872235872236
GO:BP GO:0030433 ubiquitin-dependent ERAD pathway 2.09609100946794e-11 82 116 12 0.103448275862069 0.146341463414634
GO:BP GO:0015833 peptide transport 2.09609100946794e-11 1971 136 47 0.345588235294118 0.023845763571791
GO:BP GO:0034975 protein folding in endoplasmic reticulum 2.27684878680461e-11 11 17 5 0.294117647058824 0.454545454545455
GO:BP GO:0051649 establishment of localization in cell 2.33101193777332e-11 2813 137 57 0.416058394160584 0.0202630643441166
GO:BP GO:0042886 amide transport 3.50186295066527e-11 2007 136 47 0.345588235294118 0.0234180368709517
GO:BP GO:0006820 anion transport 4.60070417893492e-11 2889 136 57 0.419117647058824 0.019730010384216
GO:BP GO:0071702 organic substance transport 1.0659991020204e-10 2766 136 55 0.404411764705882 0.019884309472162
GO:BP GO:0006457 protein folding 1.987919989597e-10 225 41 11 0.268292682926829 0.0488888888888889
GO:BP GO:0051234 establishment of localization 2.2432392965348e-10 5372 137 80 0.583941605839416 0.0148920327624721
GO:BP GO:0036498 IRE1-mediated unfolded protein response 2.83650039613925e-10 67 138 11 0.0797101449275362 0.164179104477612
GO:BP GO:0006810 transport 2.93366316214082e-10 5224 136 78 0.573529411764706 0.0149310872894334
GO:BP GO:0048193 Golgi vesicle transport 6.70069981384215e-10 382 135 20 0.148148148148148 0.0523560209424084
GO:BP GO:0034613 cellular protein localization 2.06328941705952e-09 2014 136 44 0.323529411764706 0.0218470705064548
GO:BP GO:0018279 protein N-linked glycosylation via asparagine 2.10336302956236e-09 30 128 8 0.0625 0.266666666666667
GO:BP GO:0070727 cellular macromolecule localization 2.2760661559067e-09 2024 136 44 0.323529411764706 0.0217391304347826
GO:BP GO:0018196 peptidyl-asparagine modification 2.64213578233052e-09 31 128 8 0.0625 0.258064516129032
GO:BP GO:0006811 ion transport 4.93970491789985e-09 3661 136 61 0.448529411764706 0.0166621141764545
GO:BP GO:0051641 cellular localization 5.51434672664704e-09 3541 137 60 0.437956204379562 0.0169443659983056
GO:BP GO:0006487 protein N-linked glycosylation 9.8505050604822e-09 76 128 10 0.078125 0.131578947368421
GO:BP GO:0070972 protein localization to endoplasmic reticulum 1.09350332192395e-08 146 116 12 0.103448275862069 0.0821917808219178
GO:BP GO:0008104 protein localization 1.23421211510882e-08 2770 136 51 0.375 0.0184115523465704
GO:BP GO:0006984 ER-nucleus signaling pathway 2.11450513277192e-08 53 5 4 0.8 0.0754716981132075
GO:BP GO:0006900 vesicle budding from membrane 2.56648777115273e-08 107 134 11 0.082089552238806 0.102803738317757
GO:BP GO:0036500 ATF6-mediated unfolded protein response 2.98789152759742e-08 10 4 3 0.75 0.3
GO:BP GO:0045047 protein targeting to ER 3.50465309131763e-08 113 99 10 0.101010101010101 0.0884955752212389
GO:BP GO:0072599 establishment of protein localization to endoplasmic reticulum 4.82752554888773e-08 117 99 10 0.101010101010101 0.0854700854700855
GO:BP GO:0006901 vesicle coating 1.05640788884062e-07 69 133 9 0.0676691729323308 0.130434782608696
GO:BP GO:0048199 vesicle targeting, to, from or within Golgi 1.72539055341909e-07 73 133 9 0.0676691729323308 0.123287671232877
GO:BP GO:0033554 cellular response to stress 1.87978412363256e-07 2111 18 13 0.722222222222222 0.00615821885362387
GO:BP GO:0033036 macromolecule localization 2.2100473624815e-07 3218 136 53 0.389705882352941 0.0164698570540709
GO:BP GO:1905897 regulation of response to endoplasmic reticulum stress 3.36294047647271e-07 84 6 4 0.666666666666667 0.0476190476190476
GO:BP GO:0009100 glycoprotein metabolic process 4.03864213129304e-07 424 128 17 0.1328125 0.0400943396226415
GO:BP GO:0006890 retrograde vesicle-mediated transport, Golgi to endoplasmic reticulum 4.35179122400718e-07 87 125 9 0.072 0.103448275862069
GO:BP GO:0051179 localization 1.40605314828843e-06 6901 137 84 0.613138686131387 0.0121721489639183
GO:BP GO:0006903 vesicle targeting 1.43259174470502e-06 94 133 9 0.0676691729323308 0.0957446808510638
GO:BP GO:0070085 glycosylation 2.25362130532343e-06 264 128 13 0.1015625 0.0492424242424242
GO:BP GO:0090114 COPII-coated vesicle budding 2.71758180673506e-06 72 134 8 0.0597014925373134 0.111111111111111
GO:BP GO:0036499 PERK-mediated unfolded protein response 3.4353201563527e-06 23 88 5 0.0568181818181818 0.217391304347826
GO:BP GO:0010033 response to organic substance 3.4353201563527e-06 3412 20 15 0.75 0.00439624853458382
GO:BP GO:0006613 cotranslational protein targeting to membrane 3.71377785245117e-06 102 99 8 0.0808080808080808 0.0784313725490196
GO:BP GO:1903573 negative regulation of response to endoplasmic reticulum stress 3.71377785245117e-06 46 17 4 0.235294117647059 0.0869565217391304
GO:BP GO:0006950 response to stress 4.4421335351763e-06 4170 18 15 0.833333333333333 0.00359712230215827
GO:BP GO:0010498 proteasomal protein catabolic process 4.51209884133646e-06 491 117 16 0.136752136752137 0.0325865580448065
GO:BP GO:0006605 protein targeting 4.95204571856529e-06 441 99 14 0.141414141414141 0.0317460317460317
GO:BP GO:0090317 negative regulation of intracellular protein transport 6.54701160294074e-06 41 56 5 0.0892857142857143 0.121951219512195
GO:BP GO:0006612 protein targeting to membrane 6.82283885993392e-06 204 99 10 0.101010101010101 0.0490196078431373
GO:BP GO:0140467 integrated stress response signaling 7.0067058398284e-06 27 88 5 0.0568181818181818 0.185185185185185
GO:BP GO:1904153 negative regulation of retrograde protein transport, ER to cytosol 7.56325440963793e-06 9 116 4 0.0344827586206897 0.444444444444444
GO:BP GO:0043413 macromolecule glycosylation 8.24150950163687e-06 251 128 12 0.09375 0.047808764940239
GO:BP GO:0006486 protein glycosylation 8.24150950163687e-06 251 128 12 0.09375 0.047808764940239
GO:BP GO:0051603 proteolysis involved in cellular protein catabolic process 9.26233894915576e-06 750 18 8 0.444444444444444 0.0106666666666667
GO:BP GO:0070862 negative regulation of protein exit from endoplasmic reticulum 1.18052883672252e-05 10 116 4 0.0344827586206897 0.4
GO:BP GO:0048207 vesicle targeting, rough ER to cis-Golgi 1.66481316788655e-05 65 133 7 0.0526315789473684 0.107692307692308
GO:BP GO:0048208 COPII vesicle coating 1.66481316788655e-05 65 133 7 0.0526315789473684 0.107692307692308
GO:BP GO:0044257 cellular protein catabolic process 1.66481316788655e-05 813 18 8 0.444444444444444 0.00984009840098401
GO:BP GO:0043161 proteasome-mediated ubiquitin-dependent protein catabolic process 2.77351310124895e-05 434 117 14 0.11965811965812 0.032258064516129
GO:BP GO:0032387 negative regulation of intracellular transport 2.94402806178953e-05 57 56 5 0.0892857142857143 0.087719298245614
GO:BP GO:0033365 protein localization to organelle 3.25891082055635e-05 1017 69 16 0.231884057971014 0.015732546705998
GO:BP GO:1904152 regulation of retrograde protein transport, ER to cytosol 3.49725968684718e-05 13 116 4 0.0344827586206897 0.307692307692308
GO:BP GO:0009101 glycoprotein biosynthetic process 3.49725968684718e-05 347 128 13 0.1015625 0.037463976945245
GO:BP GO:0070861 regulation of protein exit from endoplasmic reticulum 3.53010638019712e-05 27 127 5 0.0393700787401575 0.185185185185185
GO:BP GO:0042981 regulation of apoptotic process 5.26328228811644e-05 1549 20 10 0.5 0.00645577792123951
GO:BP GO:0030163 protein catabolic process 5.64740624548223e-05 974 18 8 0.444444444444444 0.0082135523613963
GO:BP GO:0043067 regulation of programmed cell death 6.22964178971936e-05 1582 20 10 0.5 0.00632111251580278
GO:BP GO:0061077 chaperone-mediated protein folding 9.05093434059164e-05 61 9 3 0.333333333333333 0.0491803278688525
GO:BP GO:0044267 cellular protein metabolic process 9.30661500843467e-05 5229 20 16 0.8 0.00305985848154523
GO:BP GO:0090150 establishment of protein localization to membrane 9.98588307991183e-05 351 99 11 0.111111111111111 0.0313390313390313
GO:BP GO:0006564 L-serine biosynthetic process 0.000117375085703583 7 90 3 0.0333333333333333 0.428571428571429
GO:BP GO:0051650 establishment of vesicle localization 0.000117375085703583 214 133 10 0.075187969924812 0.0467289719626168
GO:BP GO:0010941 regulation of cell death 0.000124479124393797 1720 20 10 0.5 0.00581395348837209
GO:BP GO:0031204 posttranslational protein targeting to membrane, translocation 0.000139369045779922 7 96 3 0.03125 0.428571428571429
GO:BP GO:1901137 carbohydrate derivative biosynthetic process 0.000164999351025416 686 66 12 0.181818181818182 0.0174927113702624
GO:BP GO:0048205 COPI coating of Golgi vesicle 0.000167627797180883 6 125 3 0.024 0.5
GO:BP GO:0035964 COPI-coated vesicle budding 0.000167627797180883 6 125 3 0.024 0.5
GO:BP GO:0071310 cellular response to organic substance 0.000167627797180883 2776 20 12 0.6 0.00432276657060519
GO:BP GO:0048200 Golgi transport vesicle coating 0.000167627797180883 6 125 3 0.024 0.5
GO:BP GO:0007029 endoplasmic reticulum organization 0.000177366399597011 87 96 6 0.0625 0.0689655172413793
GO:BP GO:1901698 response to nitrogen compound 0.000187711465446087 1172 18 8 0.444444444444444 0.0068259385665529
GO:BP GO:0051651 maintenance of location in cell 0.000187711465446087 223 4 3 0.75 0.0134529147982063
GO:BP GO:0051648 vesicle localization 0.000196020606994795 230 133 10 0.075187969924812 0.0434782608695652
GO:BP GO:0042221 response to chemical 0.000196020606994795 4781 20 15 0.75 0.00313741895001046
GO:BP GO:0006616 SRP-dependent cotranslational protein targeting to membrane, translocation 0.000216620465370026 8 99 3 0.0303030303030303 0.375
GO:BP GO:0016050 vesicle organization 0.000217056206999623 341 134 12 0.0895522388059701 0.0351906158357771
GO:BP GO:0065002 intracellular protein transmembrane transport 0.000228007362837346 52 99 5 0.0505050505050505 0.0961538461538462
GO:BP GO:1901566 organonitrogen compound biosynthetic process 0.000238880599591684 1853 115 28 0.243478260869565 0.0151106314085267
GO:BP GO:0044265 cellular macromolecule catabolic process 0.00024923659612105 1231 18 8 0.444444444444444 0.00649878147847279
GO:BP GO:0006614 SRP-dependent cotranslational protein targeting to membrane 0.0003285518331698 96 99 6 0.0606060606060606 0.0625
GO:BP GO:0019538 protein metabolic process 0.0003285518331698 5808 20 16 0.8 0.00275482093663912
GO:BP GO:1901135 carbohydrate derivative metabolic process 0.000363912655871387 1145 128 22 0.171875 0.0192139737991266
GO:BP GO:0006915 apoptotic process 0.000366181833485367 1990 20 10 0.5 0.0050251256281407
GO:BP GO:0072594 establishment of protein localization to organelle 0.000385252267743025 584 99 13 0.131313131313131 0.0222602739726027
GO:BP GO:0016192 vesicle-mediated transport 0.000410977825177502 2180 135 34 0.251851851851852 0.0155963302752294
GO:BP GO:0006563 L-serine metabolic process 0.000415097115034294 11 90 3 0.0333333333333333 0.272727272727273
GO:BP GO:0071806 protein transmembrane transport 0.000444783459119671 61 99 5 0.0505050505050505 0.0819672131147541
GO:BP GO:1901565 organonitrogen compound catabolic process 0.000463818038980601 1358 18 8 0.444444444444444 0.00589101620029455
GO:BP GO:0006508 proteolysis 0.000488180082521525 1836 18 9 0.5 0.00490196078431373
GO:BP GO:0006511 ubiquitin-dependent protein catabolic process 0.000505479892702513 655 6 4 0.666666666666667 0.00610687022900763
GO:BP GO:0051235 maintenance of location 0.000521960245584573 337 4 3 0.75 0.00890207715133531
GO:BP GO:0019941 modification-dependent protein catabolic process 0.000521960245584573 662 6 4 0.666666666666667 0.00604229607250755
GO:BP GO:0043632 modification-dependent macromolecule catabolic process 0.00054852946993287 673 6 4 0.666666666666667 0.00594353640416048
GO:BP GO:1903828 negative regulation of cellular protein localization 0.000592449627438355 116 56 5 0.0892857142857143 0.0431034482758621
GO:BP GO:0006620 posttranslational protein targeting to endoplasmic reticulum membrane 0.000619836231991598 12 96 3 0.03125 0.25
GO:BP GO:0012501 programmed cell death 0.000632046532811717 2143 20 10 0.5 0.00466635557629491
GO:BP GO:0010243 response to organonitrogen compound 0.000657875778364316 1085 84 16 0.19047619047619 0.0147465437788018
GO:BP GO:0080135 regulation of cellular response to stress 0.000706295276184208 725 6 4 0.666666666666667 0.00551724137931034
GO:BP GO:0048194 Golgi vesicle budding 0.000727485081879461 10 125 3 0.024 0.3
GO:BP GO:0035459 vesicle cargo loading 0.000732621701175623 26 134 4 0.0298507462686567 0.153846153846154
GO:BP GO:0009057 macromolecule catabolic process 0.000734789929214879 1468 18 8 0.444444444444444 0.00544959128065395
GO:BP GO:1990440 positive regulation of transcription from RNA polymerase II promoter in response to endoplasmic reticulum stress 0.000766522230348362 12 105 3 0.0285714285714286 0.25
GO:BP GO:0071712 ER-associated misfolded protein catabolic process 0.000782487793753936 12 106 3 0.0283018867924528 0.25
GO:BP GO:0043558 regulation of translational initiation in response to stress 0.000903112401263595 15 88 3 0.0340909090909091 0.2
GO:BP GO:0006464 cellular protein modification process 0.000927699883608507 4041 20 13 0.65 0.00321702548874041
GO:BP GO:0036211 protein modification process 0.000927699883608507 4041 20 13 0.65 0.00321702548874041
GO:BP GO:0070887 cellular response to chemical stimulus 0.000927699883608507 3393 20 12 0.6 0.00353669319186561
GO:BP GO:0045454 cell redox homeostasis 0.000927699883608507 58 126 5 0.0396825396825397 0.0862068965517241
GO:BP GO:0010256 endomembrane system organization 0.000927699883608507 484 96 11 0.114583333333333 0.0227272727272727
GO:BP GO:0008219 cell death 0.00100209530115513 2292 20 10 0.5 0.0043630017452007
GO:BP GO:0051224 negative regulation of protein transport 0.00105114672999743 135 56 5 0.0892857142857143 0.037037037037037
GO:BP GO:0002474 antigen processing and presentation of peptide antigen via MHC class I 0.00119648098063269 99 127 6 0.047244094488189 0.0606060606060606
GO:BP GO:1904950 negative regulation of establishment of protein localization 0.00119648098063269 139 56 5 0.0892857142857143 0.0359712230215827
GO:BP GO:0007030 Golgi organization 0.00137496054928008 147 88 6 0.0681818181818182 0.0408163265306122
GO:BP GO:0035437 maintenance of protein localization in endoplasmic reticulum 0.00149483779086536 14 116 3 0.0258620689655172 0.214285714285714
GO:BP GO:0072657 protein localization to membrane 0.00152161163448534 665 102 13 0.127450980392157 0.0195488721804511
GO:BP GO:0043412 macromolecule modification 0.00153465839041675 4257 20 13 0.65 0.00305379375146817
GO:BP GO:0032386 regulation of intracellular transport 0.00168713533865031 367 136 11 0.0808823529411765 0.0299727520435967
GO:BP GO:0009070 serine family amino acid biosynthetic process 0.00175775025061035 19 90 3 0.0333333333333333 0.157894736842105
GO:BP GO:1901564 organonitrogen compound metabolic process 0.00202756007173796 6792 20 16 0.8 0.00235571260306243
GO:BP GO:0071407 cellular response to organic cyclic compound 0.00205060636225193 587 4 3 0.75 0.00511073253833049
GO:BP GO:1904380 endoplasmic reticulum mannose trimming 0.00207899249112882 16 116 3 0.0258620689655172 0.1875
GO:BP GO:0051716 cellular response to stimulus 0.00209260000003789 7781 20 17 0.85 0.00218480915049479
GO:BP GO:0051656 establishment of organelle localization 0.00219218318297428 445 137 12 0.0875912408759124 0.0269662921348315
GO:BP GO:0006874 cellular calcium ion homeostasis 0.00235596045268913 460 5 3 0.6 0.00652173913043478
GO:BP GO:0033157 regulation of intracellular protein transport 0.00237128558794322 264 56 6 0.107142857142857 0.0227272727272727
GO:BP GO:0055074 calcium ion homeostasis 0.00247448168760465 472 5 3 0.6 0.00635593220338983
GO:BP GO:0090110 COPII-coated vesicle cargo loading 0.00247448168760465 15 134 3 0.0223880597014925 0.2
GO:BP GO:0043555 regulation of translation in response to stress 0.00265375951464426 23 88 3 0.0340909090909091 0.130434782608696
GO:BP GO:0072503 cellular divalent inorganic cation homeostasis 0.00284228390119145 497 5 3 0.6 0.00603621730382294
GO:BP GO:0072507 divalent inorganic cation homeostasis 0.0031316240097081 516 5 3 0.6 0.00581395348837209
GO:BP GO:0002478 antigen processing and presentation of exogenous peptide antigen 0.00350224961133358 174 129 7 0.0542635658914729 0.0402298850574713
GO:BP GO:0006767 water-soluble vitamin metabolic process 0.00359025060173413 84 122 5 0.040983606557377 0.0595238095238095
GO:BP GO:0043066 negative regulation of apoptotic process 0.00360742225264844 921 19 6 0.315789473684211 0.00651465798045603
GO:BP GO:0019725 cellular homeostasis 0.00361420981228099 981 7 4 0.571428571428571 0.00407747196738022
GO:BP GO:0036507 protein demannosylation 0.00367194817140301 20 116 3 0.0258620689655172 0.15
GO:BP GO:0036508 protein alpha-1,2-demannosylation 0.00367194817140301 20 116 3 0.0258620689655172 0.15
GO:BP GO:0044248 cellular catabolic process 0.00372280732417486 2347 19 9 0.473684210526316 0.00383468257349808
GO:BP GO:0071218 cellular response to misfolded protein 0.00372879291525735 22 106 3 0.0283018867924528 0.136363636363636
GO:BP GO:0043069 negative regulation of programmed cell death 0.00396647494216806 943 19 6 0.315789473684211 0.0063626723223754
GO:BP GO:0006898 receptor-mediated endocytosis 0.00426994530521947 333 8 3 0.375 0.00900900900900901
GO:BP GO:0019884 antigen processing and presentation of exogenous antigen 0.00431832586638556 182 129 7 0.0542635658914729 0.0384615384615385
GO:BP GO:0006875 cellular metal ion homeostasis 0.00433706646871573 593 5 3 0.6 0.00505902192242833
GO:BP GO:0061024 membrane organization 0.00465220408453364 973 136 18 0.132352941176471 0.0184994861253854
GO:BP GO:0051788 response to misfolded protein 0.00465566105195697 24 106 3 0.0283018867924528 0.125
GO:BP GO:1901607 alpha-amino acid biosynthetic process 0.00467647684766607 68 90 4 0.0444444444444444 0.0588235294117647
GO:BP GO:0050896 response to stimulus 0.00467981565422675 9407 20 18 0.9 0.0019134686935261
GO:BP GO:0043687 post-translational protein modification 0.00486836967935277 362 135 10 0.0740740740740741 0.0276243093922652
GO:BP GO:0036003 positive regulation of transcription from RNA polymerase II promoter in response to stress 0.00496758980031696 25 105 3 0.0285714285714286 0.12
GO:BP GO:0051223 regulation of protein transport 0.00511911118136015 586 56 8 0.142857142857143 0.0136518771331058
GO:BP GO:0009968 negative regulation of signal transduction 0.00523379473455123 1364 6 4 0.666666666666667 0.00293255131964809
GO:BP GO:0048002 antigen processing and presentation of peptide antigen 0.00553408492471969 192 129 7 0.0542635658914729 0.0364583333333333
GO:BP GO:0042149 cellular response to glucose starvation 0.0055633051755092 48 136 4 0.0294117647058824 0.0833333333333333
GO:BP GO:0055065 metal ion homeostasis 0.00568536352507199 667 5 3 0.6 0.00449775112443778
GO:BP GO:0030003 cellular cation homeostasis 0.00578075885524326 673 5 3 0.6 0.00445765230312036
GO:BP GO:0060548 negative regulation of cell death 0.00591189566044905 1038 19 6 0.315789473684211 0.00578034682080925
GO:BP GO:0006873 cellular ion homeostasis 0.0060832590384009 687 5 3 0.6 0.00436681222707424
GO:BP GO:0080134 regulation of response to stress 0.00622862250144257 1443 6 4 0.666666666666667 0.00277200277200277
GO:BP GO:0070201 regulation of establishment of protein localization 0.00636689799805292 611 56 8 0.142857142857143 0.0130932896890344
GO:BP GO:0070059 intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress 0.00636689799805292 63 108 4 0.037037037037037 0.0634920634920635
GO:BP GO:0010648 negative regulation of cell communication 0.00656221508553066 1468 6 4 0.666666666666667 0.00272479564032698
GO:BP GO:0023057 negative regulation of signaling 0.00658315582238815 1471 6 4 0.666666666666667 0.00271923861318831
GO:BP GO:0006515 protein quality control for misfolded or incompletely synthesized proteins 0.00661227694736804 28 106 3 0.0283018867924528 0.107142857142857
GO:BP GO:0014070 response to organic cyclic compound 0.00668376016475694 967 4 3 0.75 0.0031023784901758
GO:BP GO:0090087 regulation of peptide transport 0.00670386216784316 618 56 8 0.142857142857143 0.0129449838187702
GO:BP GO:1903008 organelle disassembly 0.00701756654915394 107 66 4 0.0606060606060606 0.0373831775700935
GO:BP GO:0008652 cellular amino acid biosynthetic process 0.00715847868290249 79 90 4 0.0444444444444444 0.0506329113924051
GO:BP GO:0055080 cation homeostasis 0.00721634054161894 750 5 3 0.6 0.004
GO:BP GO:0098771 inorganic ion homeostasis 0.00743366458388133 761 5 3 0.6 0.00394218134034166
GO:BP GO:0006517 protein deglycosylation 0.00793092801664608 28 116 3 0.0258620689655172 0.107142857142857
GO:BP GO:0043618 regulation of transcription from RNA polymerase II promoter in response to stress 0.00811701289492634 111 117 5 0.0427350427350427 0.045045045045045
GO:BP GO:1903792 negative regulation of anion transport 0.00823820794849756 235 56 5 0.0892857142857143 0.0212765957446809
GO:BP GO:1901575 organic substance catabolic process 0.00847584441099736 2267 18 8 0.444444444444444 0.0035288928098809
GO:BP GO:0050801 ion homeostasis 0.00860239824872028 808 5 3 0.6 0.00371287128712871
GO:BP GO:0009056 catabolic process 0.00917170628011273 2744 19 9 0.473684210526316 0.0032798833819242
GO:BP GO:0055082 cellular chemical homeostasis 0.00943524752061552 841 5 3 0.6 0.00356718192627824
GO:BP GO:0043620 regulation of DNA-templated transcription in response to stress 0.00974748254158824 117 117 5 0.0427350427350427 0.0427350427350427
GO:BP GO:0009066 aspartate family amino acid metabolic process 0.0101151511803406 49 73 3 0.0410958904109589 0.0612244897959184
GO:BP GO:0048585 negative regulation of response to stimulus 0.0105223346212298 1733 6 4 0.666666666666667 0.00230813618003462
GO:BP GO:1903827 regulation of cellular protein localization 0.0105610411762888 572 66 8 0.121212121212121 0.013986013986014
GO:BP GO:0006446 regulation of translational initiation 0.0111373904032542 80 104 4 0.0384615384615385 0.05
GO:BP GO:0042113 B cell activation 0.0112608605083316 330 26 4 0.153846153846154 0.0121212121212121
GO:BP GO:0055085 transmembrane transport 0.0121273636864693 1635 130 23 0.176923076923077 0.0140672782874618
GO:BP GO:0009069 serine family amino acid metabolic process 0.012340258746488 44 90 3 0.0333333333333333 0.0681818181818182
GO:BP GO:1903322 positive regulation of protein modification by small protein conjugation or removal 0.0126261337354571 140 106 5 0.0471698113207547 0.0357142857142857
GO:BP GO:0002479 antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent 0.0127527116636394 75 117 4 0.0341880341880342 0.0533333333333333
GO:BP GO:0007165 signal transduction 0.0128270415183957 6309 20 14 0.7 0.00221905214772547
GO:BP GO:0019882 antigen processing and presentation 0.0129136813627017 234 129 7 0.0542635658914729 0.0299145299145299
GO:BP GO:0006520 cellular amino acid metabolic process 0.0146377094960604 341 117 8 0.0683760683760684 0.0234604105571848
GO:BP GO:0032268 regulation of cellular protein metabolic process 0.0149522862395788 2541 5 4 0.8 0.00157418339236521
GO:BP GO:0032880 regulation of protein localization 0.0151735095620579 922 66 10 0.151515151515152 0.0108459869848156
GO:BP GO:0030182 neuron differentiation 0.0152511010527284 1412 4 3 0.75 0.00212464589235127
GO:BP GO:0016477 cell migration 0.0152812376317229 1649 11 5 0.454545454545455 0.00303214069132808
GO:BP GO:0042590 antigen processing and presentation of exogenous peptide antigen via MHC class I 0.0152812376317229 80 117 4 0.0341880341880342 0.05
GO:BP GO:0071495 cellular response to endogenous stimulus 0.0153127013769213 1422 4 3 0.75 0.00210970464135021
GO:BP GO:0018215 protein phosphopantetheinylation 0.0153127013769213 344 28 4 0.142857142857143 0.0116279069767442
GO:BP GO:0006518 peptide metabolic process 0.0159766290484567 955 110 14 0.127272727272727 0.0146596858638743
GO:BP GO:0006766 vitamin metabolic process 0.0161076361743916 131 122 5 0.040983606557377 0.0381679389312977
GO:BP GO:0051246 regulation of protein metabolic process 0.0178838906569299 2704 5 4 0.8 0.0014792899408284
GO:BP GO:0044260 cellular macromolecule metabolic process 0.0179760320544299 8390 20 16 0.8 0.00190703218116806
GO:BP GO:0048699 generation of neurons 0.0190018475628051 1559 4 3 0.75 0.00192431045542014
GO:BP GO:0006897 endocytosis 0.0212946836351743 696 8 3 0.375 0.00431034482758621
GO:BP GO:0043271 negative regulation of ion transport 0.0213990316074801 349 73 6 0.0821917808219178 0.0171919770773639
GO:BP GO:0023052 signaling 0.0213990316074801 6810 6 6 1 0.000881057268722467
GO:BP GO:0048878 chemical homeostasis 0.0213990316074801 1229 5 3 0.6 0.00244100895036615
GO:BP GO:0051674 localization of cell 0.0215097203153775 1828 11 5 0.454545454545455 0.00273522975929978
GO:BP GO:0048870 cell motility 0.0215097203153775 1828 11 5 0.454545454545455 0.00273522975929978
GO:BP GO:0007154 cell communication 0.0215097203153775 6829 6 6 1 0.000878605945233563
GO:BP GO:0022008 neurogenesis 0.0219587605934547 1675 4 3 0.75 0.0017910447761194
GO:BP GO:0009719 response to endogenous stimulus 0.0219587605934547 1683 4 3 0.75 0.0017825311942959
GO:BP GO:1901605 alpha-amino acid metabolic process 0.0222409215383454 198 90 5 0.0555555555555556 0.0252525252525253
GO:BP GO:0048583 regulation of response to stimulus 0.0222409215383454 4278 8 6 0.75 0.00140252454417952
GO:BP GO:0050900 leukocyte migration 0.02229984399737 511 11 3 0.272727272727273 0.00587084148727984
GO:BP GO:0065008 regulation of biological quality 0.0229806456819539 4131 24 12 0.5 0.00290486564996369
GO:BP GO:1901700 response to oxygen-containing compound 0.0233827886206901 1739 4 3 0.75 0.00172512938470385
GO:BP GO:0043603 cellular amide metabolic process 0.0235232967801089 1241 110 16 0.145454545454545 0.0128928283642224
GO:BP GO:0034248 regulation of cellular amide metabolic process 0.025260357594241 535 104 9 0.0865384615384615 0.0168224299065421
GO:BP GO:0042592 homeostatic process 0.0256818837845436 1981 7 4 0.571428571428571 0.00201918223119637
GO:BP GO:0098656 anion transmembrane transport 0.0269078573147948 550 103 9 0.087378640776699 0.0163636363636364
GO:BP GO:1903214 regulation of protein targeting to mitochondrion 0.0285000100253872 44 136 3 0.0220588235294118 0.0681818181818182
GO:BP GO:0040011 locomotion 0.0293500712558025 2028 11 5 0.454545454545455 0.002465483234714
GO:BP GO:0051640 organelle localization 0.0306986102567058 668 137 12 0.0875912408759124 0.0179640718562874
GO:BP GO:0006417 regulation of translation 0.0323107499626562 462 104 8 0.0769230769230769 0.0173160173160173
GO:BP GO:0048468 cell development 0.0347078751171747 2100 4 3 0.75 0.00142857142857143
GO:BP GO:0044070 regulation of anion transport 0.0361465624738927 896 56 8 0.142857142857143 0.00892857142857143
GO:BP GO:0006412 translation 0.0388285340639938 764 110 11 0.1 0.0143979057591623
GO:BP GO:0031399 regulation of protein modification process 0.0391617951068316 1671 5 3 0.6 0.00179533213644524
GO:BP GO:0006413 translational initiation 0.0420512519684059 201 110 5 0.0454545454545455 0.0248756218905473
GO:BP GO:0031647 regulation of protein stability 0.042877568694762 300 137 7 0.0510948905109489 0.0233333333333333
GO:BP GO:0006928 movement of cell or subcellular component 0.0432818770510058 2311 11 5 0.454545454545455 0.00216356555603635
GO:BP GO:0048523 negative regulation of cellular process 0.0446645880966482 5139 6 5 0.833333333333333 0.000972951936174353
GO:BP GO:0043043 peptide biosynthetic process 0.0451215851713814 790 110 11 0.1 0.0139240506329114
GO:BP GO:0007399 nervous system development 0.0462826202152115 2449 4 3 0.75 0.00122498979175174
GO:BP GO:0060341 regulation of cellular localization 0.0468017822246119 851 76 9 0.118421052631579 0.0105757931844888
GO:BP GO:0051604 protein maturation 0.0493996618400533 306 77 5 0.0649350649350649 0.0163398692810458
GO:BP GO:0019058 viral life cycle 0.0499115321442596 353 122 7 0.0573770491803279 0.0198300283286119
GO:CC GO:0005783 endoplasmic reticulum 6.84787356705661e-36 1982 135 75 0.555555555555556 0.0378405650857719
GO:CC GO:0098827 endoplasmic reticulum subcompartment 3.32486780806284e-32 1122 135 57 0.422222222222222 0.0508021390374332
GO:CC GO:0005789 endoplasmic reticulum membrane 2.11288049685141e-31 1117 135 56 0.414814814814815 0.0501342882721576
GO:CC GO:0042175 nuclear outer membrane-endoplasmic reticulum membrane network 4.41247943898573e-31 1139 135 56 0.414814814814815 0.0491659350307287
GO:CC GO:0031984 organelle subcompartment 2.36596989667913e-30 1773 136 66 0.485294117647059 0.0372250423011844
GO:CC GO:0140534 endoplasmic reticulum protein-containing complex 4.01478340022162e-28 128 128 25 0.1953125 0.1953125
GO:CC GO:0012505 endomembrane system 6.72844851321736e-24 4640 136 91 0.669117647058823 0.0196120689655172
GO:CC GO:0031090 organelle membrane 3.06374480532928e-20 3612 138 77 0.557971014492754 0.0213178294573643
GO:CC GO:0005737 cytoplasm 6.30535138813629e-13 11911 138 126 0.91304347826087 0.0105784568885904
GO:CC GO:0005788 endoplasmic reticulum lumen 1.03416933200878e-12 307 31 12 0.387096774193548 0.0390879478827362
GO:CC GO:0042470 melanosome 1.64808644762581e-11 105 135 13 0.0962962962962963 0.123809523809524
GO:CC GO:0048770 pigment granule 1.64808644762581e-11 105 135 13 0.0962962962962963 0.123809523809524
GO:CC GO:0043227 membrane-bounded organelle 4.4326872523776e-11 12858 138 128 0.927536231884058 0.00995489189609582
GO:CC GO:0043231 intracellular membrane-bounded organelle 1.72947739416773e-10 11296 138 119 0.86231884057971 0.0105347025495751
GO:CC GO:0008250 oligosaccharyltransferase complex 3.40716546919969e-09 13 128 6 0.046875 0.461538461538462
GO:CC GO:0044322 endoplasmic reticulum quality control compartment 4.93214506102868e-09 27 116 7 0.0603448275862069 0.259259259259259
GO:CC GO:0033018 sarcoplasmic reticulum lumen 9.14586560435281e-09 10 4 3 0.75 0.3
GO:CC GO:0000139 Golgi membrane 2.2752421289077e-08 771 136 24 0.176470588235294 0.0311284046692607
GO:CC GO:0034663 endoplasmic reticulum chaperone complex 2.2752421289077e-08 9 120 5 0.0416666666666667 0.555555555555556
GO:CC GO:0030176 integral component of endoplasmic reticulum membrane 2.45515831143776e-08 158 106 11 0.10377358490566 0.069620253164557
GO:CC GO:0000836 Hrd1p ubiquitin ligase complex 3.3869046371415e-08 10 116 5 0.0431034482758621 0.5
GO:CC GO:0031227 intrinsic component of endoplasmic reticulum membrane 3.76899637336892e-08 166 106 11 0.10377358490566 0.0662650602409639
GO:CC GO:0098588 bounding membrane of organelle 4.18637641625905e-08 2158 136 41 0.301470588235294 0.0189990732159407
GO:CC GO:0000835 ER ubiquitin ligase complex 5.40665844767141e-08 11 116 5 0.0431034482758621 0.454545454545455
GO:CC GO:0005794 Golgi apparatus 8.95094983407595e-08 1623 141 35 0.24822695035461 0.0215650030807147
GO:CC GO:0031982 vesicle 9.21501625321116e-08 4055 136 59 0.433823529411765 0.0145499383477189
GO:CC GO:0043226 organelle 1.6545288333963e-07 14008 138 128 0.927536231884058 0.00913763563677898
GO:CC GO:0070062 extracellular exosome 1.6545288333963e-07 2176 121 37 0.305785123966942 0.0170036764705882
GO:CC GO:0043229 intracellular organelle 1.80391304366049e-07 12491 138 120 0.869565217391304 0.00960691698022576
GO:CC GO:0031301 integral component of organelle membrane 1.87647782179794e-07 382 118 15 0.127118644067797 0.0392670157068063
GO:CC GO:0098791 Golgi apparatus subcompartment 2.04660876537334e-07 885 136 24 0.176470588235294 0.0271186440677966
GO:CC GO:0031410 cytoplasmic vesicle 2.75348157797571e-07 2424 136 42 0.308823529411765 0.0173267326732673
GO:CC GO:0097708 intracellular vesicle 2.80102652908382e-07 2428 136 42 0.308823529411765 0.0172981878088962
GO:CC GO:0016020 membrane 3.1452532542296e-07 9838 141 105 0.74468085106383 0.0106729009961374
GO:CC GO:0005793 endoplasmic reticulum-Golgi intermediate compartment 3.42686505298883e-07 131 135 10 0.0740740740740741 0.0763358778625954
GO:CC GO:0005622 intracellular anatomical structure 3.42686505298883e-07 14790 138 131 0.949275362318841 0.00885733603786342
GO:CC GO:0043230 extracellular organelle 3.45759704378412e-07 2263 121 37 0.305785123966942 0.0163499779054353
GO:CC GO:1903561 extracellular vesicle 3.45759704378412e-07 2261 121 37 0.305785123966942 0.0163644405130473
GO:CC GO:0031300 intrinsic component of organelle membrane 4.04926322448357e-07 413 118 15 0.127118644067797 0.036319612590799
GO:CC GO:0000153 cytoplasmic ubiquitin ligase complex 4.21940954892164e-07 17 116 5 0.0431034482758621 0.294117647058824
GO:CC GO:0036513 Derlin-1 retrotranslocation complex 5.69926953530135e-07 8 106 4 0.0377358490566038 0.5
GO:CC GO:0000839 Hrd1p ubiquitin ligase ERAD-L complex 9.97134512070866e-07 9 106 4 0.0377358490566038 0.444444444444444
GO:CC GO:0098796 membrane protein complex 1.12874857181852e-06 1322 134 28 0.208955223880597 0.0211800302571861
GO:CC GO:0016529 sarcoplasmic reticulum 1.60809673452898e-06 70 4 3 0.75 0.0428571428571429
GO:CC GO:0016528 sarcoplasm 2.27066795491358e-06 79 4 3 0.75 0.0379746835443038
GO:CC GO:0005791 rough endoplasmic reticulum 2.44346676178843e-06 86 98 7 0.0714285714285714 0.0813953488372093
GO:CC GO:0033116 endoplasmic reticulum-Golgi intermediate compartment membrane 7.51673024086451e-06 74 135 7 0.0518518518518519 0.0945945945945946
GO:CC GO:0030137 COPI-coated vesicle 8.9630999181875e-06 28 129 5 0.0387596899224806 0.178571428571429
GO:CC GO:0030135 coated vesicle 9.37771643193258e-06 295 134 12 0.0895522388059701 0.0406779661016949
GO:CC GO:0005615 extracellular space 9.37771643193258e-06 3594 28 17 0.607142857142857 0.00473010573177518
GO:CC GO:0009986 cell surface 1.26464945928625e-05 899 26 9 0.346153846153846 0.0100111234705228
GO:CC GO:0005790 smooth endoplasmic reticulum 1.58794013655268e-05 34 120 5 0.0416666666666667 0.147058823529412
GO:CC GO:0030134 COPII-coated ER to Golgi transport vesicle 2.39660198417321e-05 90 134 7 0.0522388059701493 0.0777777777777778
GO:CC GO:0030663 COPI-coated vesicle membrane 2.42225654217691e-05 18 114 4 0.0350877192982456 0.222222222222222
GO:CC GO:0016021 integral component of membrane 3.11278860863258e-05 5711 103 53 0.514563106796116 0.00928033619331115
GO:CC GO:0030133 transport vesicle 4.96974540048125e-05 414 134 13 0.0970149253731343 0.0314009661835749
GO:CC GO:0031224 intrinsic component of membrane 7.05611202971848e-05 5868 103 53 0.514563106796116 0.00903203817314247
GO:CC GO:0030867 rough endoplasmic reticulum membrane 8.29641795718203e-05 29 96 4 0.0416666666666667 0.137931034482759
GO:CC GO:0005576 extracellular region 0.000158762030332374 4567 12 10 0.833333333333333 0.00218962119553317
GO:CC GO:0030662 coated vesicle membrane 0.000224103102959855 177 134 8 0.0597014925373134 0.0451977401129944
GO:CC GO:0005798 Golgi-associated vesicle 0.000245056446270886 94 129 6 0.0465116279069767 0.0638297872340425
GO:CC GO:0030055 cell-substrate junction 0.000245056446270886 427 4 3 0.75 0.00702576112412178
GO:CC GO:0005925 focal adhesion 0.000245056446270886 420 4 3 0.75 0.00714285714285714
GO:CC GO:0030120 vesicle coat 0.000245056446270886 55 134 5 0.0373134328358209 0.0909090909090909
GO:CC GO:0012507 ER to Golgi transport vesicle membrane 0.000276053022556822 57 134 5 0.0373134328358209 0.087719298245614
GO:CC GO:0030127 COPII vesicle coat 0.000764980361286279 15 134 3 0.0223880597014925 0.2
GO:CC GO:0032991 protein-containing complex 0.00100325575833703 5548 137 60 0.437956204379562 0.0108147080028839
GO:CC GO:0048471 perinuclear region of cytoplasm 0.00110592235599344 735 4 3 0.75 0.00408163265306122
GO:CC GO:0030660 Golgi-associated vesicle membrane 0.00130083733071391 52 114 4 0.0350877192982456 0.0769230769230769
GO:CC GO:0070161 anchoring junction 0.00155909253972617 836 4 3 0.75 0.00358851674641148
GO:CC GO:1905368 peptidase complex 0.00202550953670317 96 126 5 0.0396825396825397 0.0520833333333333
GO:CC GO:0048475 coated membrane 0.00268149037737455 97 134 5 0.0373134328358209 0.0515463917525773
GO:CC GO:0030117 membrane coat 0.00268149037737455 97 134 5 0.0373134328358209 0.0515463917525773
GO:CC GO:0000502 proteasome complex 0.00403064990198881 66 126 4 0.0317460317460317 0.0606060606060606
GO:CC GO:1905369 endopeptidase complex 0.00539813375351123 72 126 4 0.0317460317460317 0.0555555555555556
GO:CC GO:0070971 endoplasmic reticulum exit site 0.00539813375351123 31 134 3 0.0223880597014925 0.0967741935483871
GO:CC GO:0070013 intracellular organelle lumen 0.0108297908030265 5402 7 6 0.857142857142857 0.00111069974083673
GO:CC GO:0043233 organelle lumen 0.0123065065553972 5565 7 6 0.857142857142857 0.00107816711590297
GO:CC GO:0005795 Golgi stack 0.0123065065553972 149 127 5 0.0393700787401575 0.0335570469798658
GO:CC GO:0031974 membrane-enclosed lumen 0.0123065065553972 5565 7 6 0.857142857142857 0.00107816711590297
GO:CC GO:0030659 cytoplasmic vesicle membrane 0.0128261599926855 779 134 13 0.0970149253731343 0.0166880616174583
GO:CC GO:0030658 transport vesicle membrane 0.0134483044476389 209 134 6 0.0447761194029851 0.0287081339712919
GO:CC GO:0030054 cell junction 0.0155690186484015 2105 11 5 0.454545454545455 0.00237529691211401
GO:CC GO:0012506 vesicle membrane 0.0155690186484015 800 134 13 0.0970149253731343 0.01625
GO:CC GO:1990234 transferase complex 0.0181547402460105 804 137 13 0.0948905109489051 0.0161691542288557
GO:CC GO:0005829 cytosol 0.0195672193754836 5303 4 4 1 0.000754290024514426
GO:CC GO:0005635 nuclear envelope 0.0195672193754836 467 67 6 0.0895522388059701 0.012847965738758
GO:CC GO:0031985 Golgi cisterna 0.0235666336682187 115 127 4 0.031496062992126 0.0347826086956522
GO:CC GO:0098552 side of membrane 0.0281906595695336 619 26 4 0.153846153846154 0.00646203554119548
GO:CC GO:0032592 integral component of mitochondrial membrane 0.0357152059088516 89 103 3 0.029126213592233 0.0337078651685393
GO:CC GO:0098573 intrinsic component of mitochondrial membrane 0.0365226012661783 90 103 3 0.029126213592233 0.0333333333333333
GO:CC GO:0005774 vacuolar membrane 0.0395815812884952 441 136 8 0.0588235294117647 0.018140589569161
GO:CC GO:1902494 catalytic complex 0.0418964335858007 1441 137 18 0.131386861313869 0.0124913254684247
GO:CC GO:0031975 envelope 0.0465513783150589 1237 138 16 0.115942028985507 0.0129345189975748
GO:CC GO:0031967 organelle envelope 0.0465513783150589 1237 138 16 0.115942028985507 0.0129345189975748
GO:MF GO:0051787 misfolded protein binding 1.23359193151237e-11 28 106 9 0.0849056603773585 0.321428571428571
GO:MF GO:0005047 signal recognition particle binding 2.51873619720456e-08 7 106 5 0.0471698113207547 0.714285714285714
GO:MF GO:0016864 intramolecular oxidoreductase activity, transposing S-S bonds 1.7426063106593e-06 19 28 4 0.142857142857143 0.210526315789474
GO:MF GO:0003756 protein disulfide isomerase activity 1.7426063106593e-06 19 28 4 0.142857142857143 0.210526315789474
GO:MF GO:0051087 chaperone binding 2.45522249286691e-06 103 17 5 0.294117647058824 0.0485436893203883
GO:MF GO:0051082 unfolded protein binding 3.27651319683693e-06 112 120 9 0.075 0.0803571428571429
GO:MF GO:0043021 ribonucleoprotein complex binding 5.48352101771107e-06 137 106 9 0.0849056603773585 0.0656934306569343
GO:MF GO:0015037 peptide disulfide oxidoreductase activity 3.82701909627762e-05 13 109 4 0.036697247706422 0.307692307692308
GO:MF GO:0004576 oligosaccharyl transferase activity 3.82701909627762e-05 6 64 3 0.046875 0.5
GO:MF GO:0016860 intramolecular oxidoreductase activity 5.08500727777928e-05 53 28 4 0.142857142857143 0.0754716981132075
GO:MF GO:1990381 ubiquitin-specific protease binding 0.000223810295443903 21 106 4 0.0377358490566038 0.19047619047619
GO:MF GO:0015036 disulfide oxidoreductase activity 0.000299883051961072 41 126 5 0.0396825396825397 0.121951219512195
GO:MF GO:0016853 isomerase activity 0.00140658463331818 169 44 5 0.113636363636364 0.029585798816568
GO:MF GO:0016667 oxidoreductase activity, acting on a sulfur group of donors 0.00147965112876914 60 126 5 0.0396825396825397 0.0833333333333333
GO:MF GO:0005525 GTP binding 0.002740491173955 381 135 11 0.0814814814814815 0.0288713910761155
GO:MF GO:0032549 ribonucleoside binding 0.0027965847058281 389 135 11 0.0814814814814815 0.0282776349614396
GO:MF GO:0001883 purine nucleoside binding 0.0027965847058281 389 135 11 0.0814814814814815 0.0282776349614396
GO:MF GO:0032550 purine ribonucleoside binding 0.0027965847058281 386 135 11 0.0814814814814815 0.0284974093264249
GO:MF GO:0001882 nucleoside binding 0.00304515705437593 395 135 11 0.0814814814814815 0.0278481012658228
GO:MF GO:0019001 guanyl nucleotide binding 0.0033106331105776 403 135 11 0.0814814814814815 0.0272952853598015
GO:MF GO:0032561 guanyl ribonucleotide binding 0.0033106331105776 403 135 11 0.0814814814814815 0.0272952853598015
GO:MF GO:0005509 calcium ion binding 0.0041926971606125 721 4 3 0.75 0.00416088765603329
GO:MF GO:0003723 RNA binding 0.0054816043018884 1943 129 27 0.209302325581395 0.0138960370560988
GO:MF GO:0016758 transferase activity, transferring hexosyl groups 0.0110449187884866 205 64 5 0.078125 0.024390243902439
GO:MF GO:0005102 signaling receptor binding 0.0147816305183611 1672 10 5 0.5 0.00299043062200957
GO:MF GO:0002020 protease binding 0.0207754336968753 133 116 5 0.0431034482758621 0.037593984962406
GO:MF GO:0097367 carbohydrate derivative binding 0.0236252697386409 2285 3 3 1 0.00131291028446389
GO:MF GO:0019899 enzyme binding 0.0247784271129738 2074 18 7 0.388888888888889 0.00337512054001929
GO:MF GO:0005515 protein binding 0.0247784271129738 14767 141 125 0.886524822695035 0.0084648202072188
GO:MF GO:0005048 signal sequence binding 0.0247784271129738 49 99 3 0.0303030303030303 0.0612244897959184
GO:MF GO:0003924 GTPase activity 0.0274964171459692 328 135 8 0.0592592592592593 0.024390243902439
GO:MF GO:0016757 transferase activity, transferring glycosyl groups 0.0280971352493428 283 39 4 0.102564102564103 0.0141342756183746
GO:MF GO:0050839 cell adhesion molecule binding 0.028801670436767 546 11 3 0.272727272727273 0.00549450549450549
GO:MF GO:0030170 pyridoxal phosphate binding 0.0331383758670125 57 111 3 0.027027027027027 0.0526315789473684
GO:MF GO:0070279 vitamin B6 binding 0.0338096453221832 58 111 3 0.027027027027027 0.0517241379310345
GO:MF GO:0008509 anion transmembrane transporter activity 0.0338096453221832 464 130 9 0.0692307692307692 0.0193965517241379
GO:MF GO:0008514 organic anion transmembrane transporter activity 0.0358979724801351 187 122 5 0.040983606557377 0.0267379679144385
GO:MF GO:1901363 heterocyclic compound binding 0.0473408925600346 6228 4 4 1 0.000642260757867694
GO:MF GO:0097159 organic cyclic compound binding 0.0475629765576276 6309 4 4 1 0.000634014899350135
GO:MF GO:0051117 ATPase binding 0.0475629765576276 86 106 3 0.0283018867924528 0.0348837209302326
GO:MF GO:0042803 protein homodimerization activity 0.0475629765576276 676 141 11 0.0780141843971631 0.0162721893491124
HPA HPA:0350473 pancreas; exocrine glandular cells[High] 9.61553294530955e-08 1879 133 54 0.406015037593985 0.028738690792975
HPA HPA:0350472 pancreas; exocrine glandular cells[≥Medium] 2.63186771524016e-05 5157 139 97 0.697841726618705 0.0188093853015319
HPA HPA:0180053 epididymis; glandular cells[High] 7.16320054953576e-05 1779 88 34 0.386363636363636 0.0191118605958404
HPA HPA:0430053 seminal vesicle; glandular cells[High] 0.00017164979065788 1410 123 36 0.292682926829268 0.025531914893617
HPA HPA:0600442 tonsil; non-germinal center cells[≥Medium] 0.000738007820677793 4079 139 78 0.561151079136691 0.019122333905369
HPA HPA:0351181 pancreas; pancreatic endocrine cells[≥Low] 0.00146164433383509 5497 139 95 0.683453237410072 0.0172821539021284
HPA HPA:0180052 epididymis; glandular cells[≥Medium] 0.00146164433383509 5560 136 94 0.691176470588235 0.0169064748201439
HPA HPA:0380513 placenta; decidual cells[High] 0.0015473313790549 1144 130 30 0.230769230769231 0.0262237762237762
HPA HPA:0420052 salivary gland; glandular cells[≥Medium] 0.00156480138801031 4742 139 85 0.611510791366906 0.0179249261914804
HPA HPA:0550052 stomach 2; glandular cells[≥Medium] 0.00245017556245855 6134 132 97 0.734848484848485 0.0158134985327682
HPA HPA:0540053 stomach 1; glandular cells[High] 0.00255584160212846 2365 106 41 0.386792452830189 0.0173361522198732
HPA HPA:0420053 salivary gland; glandular cells[High] 0.00280244817411763 1418 133 34 0.255639097744361 0.0239774330042313
HPA HPA:0590053 thyroid gland; glandular cells[High] 0.00280244817411763 1804 9 7 0.777777777777778 0.00388026607538803
HPA HPA:0600441 tonsil; non-germinal center cells[≥Low] 0.00280244817411763 5966 139 99 0.712230215827338 0.0165940328528327
HPA HPA:0310442 lymph node; non-germinal center cells[≥Medium] 0.00307121333242418 3875 99 54 0.545454545454545 0.0139354838709677
HPA HPA:0350471 pancreas; exocrine glandular cells[≥Low] 0.00307121333242418 6778 133 104 0.781954887218045 0.0153437592210091
HPA HPA:0380523 placenta; trophoblastic cells[High] 0.00325483736192269 1998 135 43 0.318518518518519 0.0215215215215215
HPA HPA:0310441 lymph node; non-germinal center cells[≥Low] 0.00343964600026118 5915 111 80 0.720720720720721 0.0135249366018597
HPA HPA:0291161 liver; cholangiocytes[≥Low] 0.00527571202485594 3867 138 70 0.507246376811594 0.0181018877682958
HPA HPA:0290402 liver; hepatocytes[≥Medium] 0.00578074869191497 3640 139 67 0.482014388489209 0.0184065934065934
HPA HPA:0600431 tonsil; germinal center cells[≥Low] 0.00578074869191497 5845 136 94 0.691176470588235 0.016082121471343
HPA HPA:0430052 seminal vesicle; glandular cells[≥Medium] 0.0059502645591295 5096 133 83 0.62406015037594 0.016287284144427
HPA HPA:0390052 prostate; glandular cells[≥Medium] 0.00837476016372097 4699 136 79 0.580882352941177 0.0168120876782294
HPA HPA:0160053 endometrium 1; glandular cells[High] 0.0115239205308193 1413 98 25 0.255102040816327 0.0176928520877565
HPA HPA:0430051 seminal vesicle; glandular cells[≥Low] 0.0132402663192651 6672 133 100 0.75187969924812 0.0149880095923261
HPA HPA:0310000 lymph node 0.0132402663192651 6374 111 82 0.738738738738739 0.0128647631000941
HPA HPA:0160251 endometrium 1; cells in endometrial stroma[≥Low] 0.0132402663192651 3962 7 7 1 0.00176678445229682
HPA HPA:0430000 seminal vesicle 0.0132402663192651 6672 133 100 0.75187969924812 0.0149880095923261
HPA HPA:0080133 caudate; neuronal cells[High] 0.0132656913870983 1059 3 3 1 0.0028328611898017
HPA HPA:0350000 pancreas 0.0140897547287211 7242 133 106 0.796992481203007 0.0146368406517537
HPA HPA:0380522 placenta; trophoblastic cells[≥Medium] 0.0140897547287211 5074 139 84 0.60431654676259 0.0165549862041782
HPA HPA:0380512 placenta; decidual cells[≥Medium] 0.0144858704169093 3463 43 24 0.558139534883721 0.00693040716142073
HPA HPA:0040082 bone marrow; hematopoietic cells[≥Medium] 0.0149257331837927 4126 7 7 1 0.0016965584100824
HPA HPA:0500112 soft tissue 1; chondrocytes[≥Medium] 0.0152343441439467 1395 93 23 0.247311827956989 0.0164874551971326
HPA HPA:0420051 salivary gland; glandular cells[≥Low] 0.0152343441439467 6744 133 100 0.75187969924812 0.0148279952550415
HPA HPA:0530711 spleen; cells in red pulp[≥Low] 0.0152343441439467 5195 128 79 0.6171875 0.0152069297401347
HPA HPA:0420000 salivary gland 0.0152343441439467 6744 133 100 0.75187969924812 0.0148279952550415
HPA HPA:0250133 hippocampus; neuronal cells[High] 0.0152343441439467 1210 3 3 1 0.00247933884297521
HPA HPA:0100132 cerebral cortex; neuronal cells[≥Medium] 0.0152343441439467 4883 133 78 0.586466165413534 0.0159737866065943
HPA HPA:0310431 lymph node; germinal center cells[≥Low] 0.0154283672564122 4935 136 80 0.588235294117647 0.0162107396149949
HPA HPA:0540052 stomach 1; glandular cells[≥Medium] 0.0154283672564122 6201 132 93 0.704545454545455 0.0149975810353169
HPA HPA:0351182 pancreas; pancreatic endocrine cells[≥Medium] 0.0158018656051058 3523 135 61 0.451851851851852 0.0173147885325007
HPA HPA:0170053 endometrium 2; glandular cells[High] 0.015841383657486 1282 3 3 1 0.00234009360374415
HPA HPA:0310432 lymph node; germinal center cells[≥Medium] 0.015841383657486 3209 136 57 0.419117647058824 0.0177625428482393
HPA HPA:0190221 esophagus; squamous epithelial cells[≥Low] 0.018507962529801 6524 99 74 0.747474747474748 0.0113427345187002
HPA HPA:0190000 esophagus 0.018507962529801 6524 99 74 0.747474747474748 0.0113427345187002
HPA HPA:0550053 stomach 2; glandular cells[High] 0.018507962529801 2350 123 41 0.333333333333333 0.0174468085106383
HPA HPA:0480052 small intestine; glandular cells[≥Medium] 0.018507962529801 6461 139 100 0.719424460431655 0.0154774802662127
HPA HPA:0500701 soft tissue 1; peripheral nerve[≥Low] 0.018507962529801 2740 107 41 0.383177570093458 0.014963503649635
HPA HPA:0460651 skin 1; fibroblasts[≥Low] 0.0253692111423437 4726 138 77 0.557971014492754 0.0162928480744816
HPA HPA:0300412 lung; macrophages[≥Medium] 0.0253692111423437 4732 7 7 1 0.0014792899408284
HPA HPA:0590000 thyroid gland 0.0263119979823748 6963 133 101 0.759398496240602 0.0145052419933937
HPA HPA:0110051 cervix, uterine; glandular cells[≥Low] 0.0263119979823748 5579 128 82 0.640625 0.0146979745474099
HPA HPA:0590051 thyroid gland; glandular cells[≥Low] 0.0263119979823748 6963 133 101 0.759398496240602 0.0145052419933937
HPA HPA:0530000 spleen 0.0313596219615695 5756 132 86 0.651515151515151 0.0149409312022238
HPA HPA:0160252 endometrium 1; cells in endometrial stroma[≥Medium] 0.0329611513086926 2142 7 5 0.714285714285714 0.00233426704014939
HPA HPA:0250132 hippocampus; neuronal cells[≥Medium] 0.0336484641736832 4126 135 67 0.496296296296296 0.0162384876393602
HPA HPA:0290401 liver; hepatocytes[≥Low] 0.0336484641736832 5611 132 84 0.636363636363636 0.0149705934770986
HPA HPA:0160051 endometrium 1; glandular cells[≥Low] 0.0336484641736832 6663 133 97 0.729323308270677 0.0145580069037971
HPA HPA:0380511 placenta; decidual cells[≥Low] 0.0340521098042518 4716 132 73 0.553030303030303 0.015479219677693
HPA HPA:0110052 cervix, uterine; glandular cells[≥Medium] 0.0340521098042518 3938 139 66 0.474820143884892 0.0167597765363128
HPA HPA:0340461 ovary; ovarian stroma cells[≥Low] 0.0340521098042518 3894 138 65 0.471014492753623 0.0166923472008218
HPA HPA:0170251 endometrium 2; cells in endometrial stroma[≥Low] 0.0340521098042518 3410 7 6 0.857142857142857 0.00175953079178886
HPA HPA:0040000 bone marrow 0.0340521098042518 6349 139 97 0.697841726618705 0.0152779965348874
HPA HPA:0040081 bone marrow; hematopoietic cells[≥Low] 0.0340521098042518 6349 139 97 0.697841726618705 0.0152779965348874
HPA HPA:0340000 ovary 0.0364447732883729 5298 136 82 0.602941176470588 0.0154775386938467
HPA HPA:0160052 endometrium 1; glandular cells[≥Medium] 0.0364447732883729 5014 139 80 0.575539568345324 0.0159553250897487
HPA HPA:0160000 endometrium 1 0.0403338242330365 6894 133 99 0.744360902255639 0.0143603133159269
HPA HPA:0380521 placenta; trophoblastic cells[≥Low] 0.0403338242330365 6388 139 97 0.697841726618705 0.015184721352536
HPA HPA:0180051 epididymis; glandular cells[≥Low] 0.0410778128691123 7171 133 102 0.766917293233083 0.0142239576070283
HPA HPA:0150052 duodenum; glandular cells[≥Medium] 0.0410778128691123 6480 139 98 0.705035971223022 0.0151234567901235
HPA HPA:0180000 epididymis 0.0410778128691123 7171 133 102 0.766917293233083 0.0142239576070283
HPA HPA:0110221 cervix, uterine; squamous epithelial cells[≥Low] 0.0410778128691123 5325 7 7 1 0.00131455399061033
HPA HPA:0460671 skin 1; melanocytes[≥Low] 0.0420285526182962 5378 7 7 1 0.0013015991074749
HPA HPA:0590052 thyroid gland; glandular cells[≥Medium] 0.0428693774961423 5454 139 85 0.611510791366906 0.0155848918225156
HPA HPA:0500651 soft tissue 1; fibroblasts[≥Low] 0.0428693774961423 4156 56 31 0.553571428571429 0.00745909528392685
HPA HPA:0090161 cerebellum; Purkinje cells[≥Low] 0.0449303185145646 5460 7 7 1 0.00128205128205128
HPA HPA:0360000 parathyroid gland 0.0456627863158116 5767 38 28 0.736842105263158 0.0048552106814635
HPA HPA:0360051 parathyroid gland; glandular cells[≥Low] 0.0456627863158116 5767 38 28 0.736842105263158 0.0048552106814635
HPA HPA:0390053 prostate; glandular cells[High] 0.0466000173738955 1284 103 21 0.203883495145631 0.0163551401869159
HPA HPA:0390000 prostate 0.04839167900653 6528 139 98 0.705035971223022 0.0150122549019608
HPA HPA:0390051 prostate; glandular cells[≥Low] 0.04839167900653 6528 139 98 0.705035971223022 0.0150122549019608
HPA HPA:0540051 stomach 1; glandular cells[≥Low] 0.048494537533044 7493 133 105 0.789473684210526 0.0140130788736154
HPA HPA:0540000 stomach 1 0.048494537533044 7493 133 105 0.789473684210526 0.0140130788736154
HPA HPA:0600432 tonsil; germinal center cells[≥Medium] 0.048494537533044 3988 136 64 0.470588235294118 0.0160481444332999
HPA HPA:0050011 breast; adipocytes[≥Low] 0.048494537533044 2725 9 6 0.666666666666667 0.00220183486238532
HPA HPA:0090191 cerebellum; cells in molecular layer[≥Low] 0.048494537533044 4336 5 5 1 0.00115313653136531
HPA HPA:0500000 soft tissue 1 0.048494537533044 5242 132 78 0.590909090909091 0.0148798168637924
HPA HPA:0500652 soft tissue 1; fibroblasts[≥Medium] 0.0490608807859117 2649 123 42 0.341463414634146 0.0158550396375991
HPA HPA:0320102 nasopharynx; respiratory epithelial cells[≥Medium] 0.0498725270949187 5010 67 41 0.611940298507463 0.00818363273453094
KEGG KEGG:04141 Protein processing in endoplasmic reticulum 1.14637335870172e-24 170 134 33 0.246268656716418 0.194117647058824
KEGG KEGG:03060 Protein export 9.28895468195117e-09 23 99 8 0.0808080808080808 0.347826086956522
KEGG KEGG:04918 Thyroid hormone synthesis 0.000961422028550414 75 7 3 0.428571428571429 0.04
KEGG KEGG:05110 Vibrio cholerae infection 0.00371580618179828 50 129 6 0.0465116279069767 0.12
KEGG KEGG:04612 Antigen processing and presentation 0.00678861046671165 69 16 3 0.1875 0.0434782608695652
KEGG KEGG:00510 N-Glycan biosynthesis 0.0466408040109099 50 97 4 0.0412371134020619 0.08
MIRNA MIRNA:hsa-miR-3664-3p hsa-miR-3664-3p 0.000410669612998617 172 6 4 0.666666666666667 0.0232558139534884
MIRNA MIRNA:hsa-miR-1185-5p hsa-miR-1185-5p 0.046362952112649 68 24 3 0.125 0.0441176470588235
MIRNA MIRNA:hsa-miR-922 hsa-miR-922 0.046362952112649 160 114 7 0.0614035087719298 0.04375
MIRNA MIRNA:hsa-miR-376a-5p hsa-miR-376a-5p 0.046362952112649 69 28 3 0.107142857142857 0.0434782608695652
MIRNA MIRNA:hsa-miR-345-5p hsa-miR-345-5p 0.046362952112649 50 37 3 0.0810810810810811 0.06
MIRNA MIRNA:hsa-miR-3159 hsa-miR-3159 0.046362952112649 86 83 5 0.0602409638554217 0.0581395348837209
MIRNA MIRNA:hsa-miR-16-5p hsa-miR-16-5p 0.046362952112649 1556 111 25 0.225225225225225 0.0160668380462725
MIRNA MIRNA:hsa-miR-1290 hsa-miR-1290 0.046362952112649 74 23 3 0.130434782608696 0.0405405405405405
MIRNA MIRNA:hsa-miR-1-3p hsa-miR-1-3p 0.046362952112649 915 20 7 0.35 0.00765027322404372
REAC REAC:R-HSA-381119 Unfolded Protein Response (UPR) 1.4403099363486e-14 91 110 17 0.154545454545455 0.186813186813187
REAC REAC:R-HSA-446203 Asparagine N-linked glycosylation 1.4403099363486e-14 304 133 28 0.210526315789474 0.0921052631578947
REAC REAC:R-HSA-392499 Metabolism of proteins 3.41794377154053e-11 1961 138 63 0.456521739130435 0.0321264660887302
REAC REAC:R-HSA-381070 IRE1alpha activates chaperones 2.71041938514249e-09 49 138 11 0.0797101449275362 0.224489795918367
REAC REAC:R-HSA-381038 XBP1(S) activates chaperone genes 3.20764737087155e-08 47 138 10 0.072463768115942 0.212765957446809
REAC REAC:R-HSA-1799339 SRP-dependent cotranslational protein targeting to membrane 3.94497214346159e-08 113 99 12 0.121212121212121 0.106194690265487
REAC REAC:R-HSA-381183 ATF6 (ATF6-alpha) activates chaperone genes 1.08116175128109e-07 9 4 3 0.75 0.333333333333333
REAC REAC:R-HSA-381033 ATF6 (ATF6-alpha) activates chaperones 1.85798219068781e-07 11 4 3 0.75 0.272727272727273
REAC REAC:R-HSA-199977 ER to Golgi Anterograde Transport 3.72861436294443e-07 154 133 14 0.105263157894737 0.0909090909090909
REAC REAC:R-HSA-948021 Transport to the Golgi and subsequent modification 4.57174497663572e-07 185 133 15 0.112781954887218 0.0810810810810811
REAC REAC:R-HSA-5678895 Defective CFTR causes cystic fibrosis 8.00481152335557e-07 61 117 9 0.0769230769230769 0.147540983606557
REAC REAC:R-HSA-532668 N-glycan trimming in the ER and Calnexin/Calreticulin cycle 3.10911403119801e-06 35 116 7 0.0603448275862069 0.2
REAC REAC:R-HSA-5619084 ABC transporter disorders 5.4329552832164e-06 77 117 9 0.0769230769230769 0.116883116883117
REAC REAC:R-HSA-382556 ABC-family proteins mediated transport 5.99201973748313e-06 103 117 10 0.0854700854700855 0.0970873786407767
REAC REAC:R-HSA-9648895 Response of EIF2AK1 (HRI) to heme deficiency 9.14650355390616e-06 15 110 5 0.0454545454545455 0.333333333333333
REAC REAC:R-HSA-72766 Translation 9.16161843389496e-06 292 110 15 0.136363636363636 0.0513698630136986
REAC REAC:R-HSA-6807878 COPI-mediated anterograde transport 1.12652426945563e-05 102 129 10 0.0775193798449612 0.0980392156862745
REAC REAC:R-HSA-381042 PERK regulates gene expression 1.9977400706334e-05 32 110 6 0.0545454545454545 0.1875
REAC REAC:R-HSA-597592 Post-translational protein modification 2.8880241847359e-05 1377 137 39 0.284671532846715 0.028322440087146
REAC REAC:R-HSA-5362768 Hh mutants are degraded by ERAD 5.63318523030149e-05 56 117 7 0.0598290598290598 0.125
REAC REAC:R-HSA-6811434 COPI-dependent Golgi-to-ER retrograde traffic 7.24154127001814e-05 100 129 9 0.0697674418604651 0.09
REAC REAC:R-HSA-5387390 Hh mutants abrogate ligand secretion 7.32921221834754e-05 59 117 7 0.0598290598290598 0.11864406779661
REAC REAC:R-HSA-5619115 Disorders of transmembrane transporters 8.65862377727132e-05 173 121 11 0.0909090909090909 0.0635838150289017
REAC REAC:R-HSA-983170 Antigen Presentation: Folding, assembly and peptide loading of class I MHC 0.000118493841667433 25 16 3 0.1875 0.12
REAC REAC:R-HSA-5358346 Hedgehog ligand biogenesis 0.000124595124891355 65 117 7 0.0598290598290598 0.107692307692308
REAC REAC:R-HSA-901042 Calnexin/calreticulin cycle 0.000136853111951515 26 116 5 0.0431034482758621 0.192307692307692
REAC REAC:R-HSA-204005 COPII-mediated vesicle transport 0.000315958096364799 67 133 7 0.0526315789473684 0.104477611940299
REAC REAC:R-HSA-8856688 Golgi-to-ER retrograde transport 0.000563420955114294 134 129 9 0.0697674418604651 0.0671641791044776
REAC REAC:R-HSA-2173782 Binding and Uptake of Ligands by Scavenger Receptors 0.000563420955114294 95 8 3 0.375 0.0315789473684211
REAC REAC:R-HSA-380994 ATF4 activates genes in response to endoplasmic reticulum stress 0.00193977805798329 27 105 4 0.0380952380952381 0.148148148148148
REAC REAC:R-HSA-8957275 Post-translational protein phosphorylation 0.00234021475893237 107 28 4 0.142857142857143 0.0373831775700935
REAC REAC:R-HSA-6811442 Intra-Golgi and retrograde Golgi-to-ER traffic 0.00251534797781728 203 129 10 0.0775193798449612 0.0492610837438424
REAC REAC:R-HSA-5653656 Vesicle-mediated transport 0.00307345645674562 717 133 21 0.157894736842105 0.0292887029288703
REAC REAC:R-HSA-1236974 ER-Phagosome pathway 0.00307616121936298 83 16 3 0.1875 0.036144578313253
REAC REAC:R-HSA-381426 Regulation of Insulin-like Growth Factor (IGF) transport and uptake by Insulin-like Growth Factor Binding Proteins (IGFBPs) 0.00356697936334309 124 28 4 0.142857142857143 0.032258064516129
REAC REAC:R-HSA-1236975 Antigen processing-Cross presentation 0.00468340972725134 99 16 3 0.1875 0.0303030303030303
REAC REAC:R-HSA-162658 Golgi Cisternae Pericentriolar Stack Reorganization 0.00573686670449281 13 135 3 0.0222222222222222 0.230769230769231
REAC REAC:R-HSA-5358351 Signaling by Hedgehog 0.0129739323488451 149 117 7 0.0598290598290598 0.0469798657718121
REAC REAC:R-HSA-901032 ER Quality Control Compartment (ERQC) 0.0142132952572795 21 116 3 0.0258620689655172 0.142857142857143
REAC REAC:R-HSA-983169 Class I MHC mediated antigen processing & presentation 0.0174402797854756 370 16 4 0.25 0.0108108108108108
REAC REAC:R-HSA-382551 Transport of small molecules 0.0256207646233006 718 130 18 0.138461538461538 0.0250696378830084
REAC REAC:R-HSA-109582 Hemostasis 0.0287628414564552 657 11 4 0.363636363636364 0.0060882800608828
REAC REAC:R-HSA-8866654 E3 ubiquitin ligases ubiquitinate target proteins 0.039784400360444 53 137 4 0.0291970802919708 0.0754716981132075
REAC REAC:R-HSA-199991 Membrane Trafficking 0.0420754247282843 625 133 16 0.120300751879699 0.0256
REAC REAC:R-HSA-1280218 Adaptive Immune System 0.0420754247282843 800 16 5 0.3125 0.00625
REAC REAC:R-HSA-446219 Synthesis of substrates in N-glycan biosythesis 0.0495987951751063 63 64 3 0.046875 0.0476190476190476
TF TF:M01770_1 Factor: XBP-1; motif: WNNGMCACGTC; match class: 1 2.63457553402376e-09 4554 141 72 0.51063829787234 0.0158102766798419
TF TF:M11276 Factor: XBP-1; motif: NNMCACGTCANN 1.08848063669672e-08 551 135 23 0.17037037037037 0.0417422867513612
TF TF:M11256 Factor: AIBZIP; motif: NGCCACGTCAYN 1.13224168557039e-07 1323 135 33 0.244444444444444 0.0249433106575964
TF TF:M04744_1 Factor: ATF-3; motif: GGCGCSSNSNGRTSACGTSA; match class: 1 7.52503693445006e-07 4889 141 69 0.48936170212766 0.0141133156064635
TF TF:M11529_1 Factor: E2F-2; motif: GCGCGCGCNCS; match class: 1 8.20621064475325e-07 14473 141 132 0.936170212765957 0.00912043114765425
TF TF:M04228 Factor: XBP1; motif: WNNGMCACGTCATC 9.57465768131656e-07 57 111 8 0.0720720720720721 0.140350877192982
TF TF:M11221_1 Factor: CREB1; motif: RTGACGYGTCAN; match class: 1 9.57465768131656e-07 5695 126 69 0.547619047619048 0.0121158911325724
TF TF:M00716_1 Factor: ZF5; motif: GSGCGCGR; match class: 1 1.05447451153173e-06 14106 140 129 0.921428571428571 0.00914504466184602
TF TF:M10438_1 Factor: ZF5; motif: GGSGCGCGS; match class: 1 2.13483826602325e-06 14873 140 132 0.942857142857143 0.00887514287635312
TF TF:M10438 Factor: ZF5; motif: GGSGCGCGS 3.4828529620814e-06 16228 141 138 0.978723404255319 0.00850382055706187
TF TF:M11430 Factor: PEA3; motif: NACCGGAAGTN 6.43472625527181e-06 10865 141 110 0.780141843971631 0.0101242521859181
TF TF:M09894_1 Factor: E2F-4; motif: SNGGGCGGGAANN; match class: 1 7.97092232056499e-06 13929 137 124 0.905109489051095 0.008902290185943
TF TF:M11235 Factor: OASIS; motif: YGCCACGTCANC 9.38653596961401e-06 368 130 15 0.115384615384615 0.0407608695652174
TF TF:M11247 Factor: Luman; motif: YGCCACGTCAYC 9.38653596961401e-06 174 130 11 0.0846153846153846 0.0632183908045977
TF TF:M01240_1 Factor: BEN; motif: CAGCGRNV; match class: 1 9.38653596961401e-06 13227 119 106 0.890756302521008 0.00801391093974446
TF TF:M08526_1 Factor: E2F-3:HES-7; motif: NNNSGCGCSNNNNNCRCGYGNN; match class: 1 1.14761506590389e-05 14997 141 132 0.936170212765957 0.00880176035207041
TF TF:M11256_1 Factor: AIBZIP; motif: NGCCACGTCAYN; match class: 1 1.28566854757144e-05 75 130 8 0.0615384615384615 0.106666666666667
TF TF:M11529 Factor: E2F-2; motif: GCGCGCGCNCS 1.94475501330576e-05 16263 141 137 0.971631205673759 0.00842403000676382
TF TF:M00483 Factor: ATF6; motif: TGACGTGG 2.22893056426798e-05 2627 140 43 0.307142857142857 0.0163684811572136
TF TF:M02065_1 Factor: ER81; motif: RCCGGAARYN; match class: 1 2.22893056426798e-05 6749 136 77 0.566176470588235 0.0114090976440954
TF TF:M01770 Factor: XBP-1; motif: WNNGMCACGTC 2.37366407548919e-05 11003 141 109 0.773049645390071 0.00990638916659093
TF TF:M01861 Factor: ATF-1; motif: TNACGTCAN 2.45333302083009e-05 6294 140 75 0.535714285714286 0.0119161105815062
TF TF:M07034 Factor: ATF-1; motif: NNNTGACGTNNN 2.45333302083009e-05 4248 140 58 0.414285714285714 0.013653483992467
TF TF:M11227 Factor: ATF-6; motif: TGRTGACGTGGCAN 2.47632163866174e-05 201 130 11 0.0846153846153846 0.054726368159204
TF TF:M01820 Factor: CREM; motif: TGACGTCASYN 2.47632163866174e-05 6303 140 75 0.535714285714286 0.0118990956687292
TF TF:M00179 Factor: ATF2; motif: VGTGACGTMACN 2.54653365815226e-05 6065 140 73 0.521428571428571 0.0120362737015664
TF TF:M00716 Factor: ZF5; motif: GSGCGCGR 2.54653365815226e-05 16103 141 136 0.964539007092199 0.00844563124883562
TF TF:M10530 Factor: sp4; motif: NNNGCYCCGCCCCCY 3.20089066809103e-05 8227 108 72 0.666666666666667 0.00875167132612131
TF TF:M00017 Factor: ATF; motif: CNSTGACGTNNNYC 3.49865671750464e-05 7226 141 82 0.581560283687943 0.0113479103238306
TF TF:M00736 Factor: E2F-1:DP-1; motif: TTTCSCGC 3.77899972663796e-05 10390 125 94 0.752 0.00904716073147257
TF TF:M02089 Factor: E2F-3; motif: GGCGGGN 3.77899972663796e-05 13173 115 101 0.878260869565217 0.00766719805663099
TF TF:M09894 Factor: E2F-4; motif: SNGGGCGGGAANN 4.10676157668528e-05 16194 141 136 0.964539007092199 0.00839817216252933
TF TF:M11427 Factor: PEA3; motif: NACCGGAAGTN 5.14304078353863e-05 10585 141 105 0.74468085106383 0.00991969768540387
TF TF:M00917 Factor: CREB; motif: CNNTGACGTMA 5.14304078353863e-05 5578 140 68 0.485714285714286 0.012190749372535
TF TF:M02066 Factor: PEA3; motif: RCCGGAAGYN 5.14304078353863e-05 7045 141 80 0.567375886524823 0.0113555713271824
TF TF:M03975_1 Factor: ERG; motif: ACCGGAARTN; match class: 1 5.16366599080109e-05 4024 134 53 0.395522388059701 0.0131709741550696
TF TF:M00039 Factor: CREB; motif: TGACGTMA 5.16846376204748e-05 5222 140 65 0.464285714285714 0.0124473381846036
TF TF:M08207_1 Factor: E2F-3:TBR2; motif: ANGTGYKANGGCGCSTTNNCRNNT; match class: 1 5.78495637259931e-05 15466 137 129 0.941605839416058 0.00834087676192939
TF TF:M00113 Factor: CREB; motif: NNGNTGACGTNN 6.1736098787497e-05 4801 107 50 0.467289719626168 0.0104144969797959
TF TF:M07206 Factor: E2F-1; motif: NGGGCGGGARV 6.65959348594111e-05 14575 141 128 0.907801418439716 0.00878216123499142
TF TF:M10005 Factor: NF-YA; motif: NYRRCCAATCAGAR 7.50768891136784e-05 2225 134 36 0.26865671641791 0.0161797752808989
TF TF:M10072 Factor: sp4; motif: NNGNARGRGGCGGRGCNNRR 8.74865903038203e-05 10494 140 103 0.735714285714286 0.00981513245664189
TF TF:M00196 Factor: Sp1; motif: NGGGGGCGGGGYN 9.78467856804181e-05 10233 135 98 0.725925925925926 0.00957685918108082
TF TF:M07313 Factor: ATF-3; motif: SNTGACGYNATN 9.78467856804181e-05 2894 129 41 0.317829457364341 0.0141672425708362
TF TF:M11430_1 Factor: PEA3; motif: NACCGGAAGTN; match class: 1 0.000103074788215892 4902 139 61 0.438848920863309 0.0124439004487964
TF TF:M11424 Factor: Erm; motif: NNSCGGAWGYN 0.000109454988220669 8149 139 86 0.618705035971223 0.0105534421401399
TF TF:M00931 Factor: Sp1; motif: GGGGCGGGGC 0.000121072374660199 10281 135 98 0.725925925925926 0.00953214667833868
TF TF:M02064 Factor: c-ets-2; motif: ACCGGAWRTN 0.000123433721034939 10939 141 106 0.75177304964539 0.00969009964347747
TF TF:M02065 Factor: ER81; motif: RCCGGAARYN 0.000123433721034939 12550 141 116 0.822695035460993 0.00924302788844622
TF TF:M00483_1 Factor: ATF6; motif: TGACGTGG; match class: 1 0.000133950244781045 246 135 11 0.0814814814814815 0.0447154471544715
TF TF:M00916 Factor: CREB; motif: NNTKACGTCANNNS 0.000133950244781045 5889 140 69 0.492857142857143 0.0117167600611309
TF TF:M04744 Factor: ATF-3; motif: GGCGCSSNSNGRTSACGTSA 0.000160197808361863 10089 141 100 0.709219858156028 0.00991178511249876
TF TF:M02106 Factor: NF-YA; motif: CRGCCAATCAGNRN 0.000160197808361863 1741 75 21 0.28 0.0120620333141872
TF TF:M11531 Factor: E2F-2; motif: GCGCGCGCGYW 0.000166766340526477 13270 140 119 0.85 0.00896759608138659
TF TF:M11396_1 Factor: Erg; motif: NACCGGAARTN; match class: 1 0.000166766340526477 4963 134 59 0.440298507462687 0.0118879709852912
TF TF:M04168_1 Factor: CLOCK; motif: AACACGTGTN; match class: 1 0.000166766340526477 183 10 4 0.4 0.0218579234972678
TF TF:M11274 Factor: XBP-1; motif: NGMCACRTCAYC 0.000166766340526477 1759 139 31 0.223021582733813 0.0176236498010233
TF TF:M07248 Factor: CREB1; motif: NNNNTGACGTNANNN 0.000177458014679623 4266 140 55 0.392857142857143 0.012892639474918
TF TF:M00981 Factor: CREB,; motif: NTGACGTNA 0.000183190403064304 8345 140 87 0.621428571428571 0.0104254044337927
TF TF:M11392 Factor: Erg; motif: NACCGGAARYN 0.000183190403064304 8690 141 90 0.638297872340426 0.0103567318757192
TF TF:M03988 Factor: FLI1; motif: ACCGGAARTN 0.000235287513608735 8318 141 87 0.617021276595745 0.0104592450108199
TF TF:M11250 Factor: Luman; motif: NGCCACGTCAYN 0.000240520398774506 223 130 10 0.0769230769230769 0.0448430493273543
TF TF:M03977 Factor: ETS1; motif: ACCGGAARYN 0.000240520398774506 10512 136 99 0.727941176470588 0.00941780821917808
TF TF:M04826_1 Factor: p300; motif: ACNTCCG; match class: 1 0.000255736354577554 15260 141 130 0.921985815602837 0.00851900393184797
TF TF:M01752 Factor: ERG; motif: ACCGGAART 0.000257835387843304 9474 141 95 0.673758865248227 0.0100274435296601
TF TF:M12173 Factor: GKLF; motif: NNCCMCRCCCN 0.000263005307210186 10023 125 89 0.712 0.00887957697296219
TF TF:M07395 Factor: Sp1; motif: NGGGGCGGGGN 0.000263970181063961 10640 135 99 0.733333333333333 0.00930451127819549
TF TF:M11229 Factor: ATF-6; motif: TGRTGACGTGGCAN 0.000266964636466023 342 130 12 0.0923076923076923 0.0350877192982456
TF TF:M01078 Factor: c-Ets-1; motif: NNNRCCGGAWRYNNNN 0.000266964636466023 7544 141 81 0.574468085106383 0.0107370095440085
TF TF:M00327_1 Factor: Pax-3; motif: NNNNNNCGTCACGSTYNNNNN; match class: 1 0.000267353718449744 6888 141 76 0.539007092198582 0.0110336817653891
TF TF:M02064_1 Factor: c-ets-2; motif: ACCGGAWRTN; match class: 1 0.000289137809169088 4592 140 57 0.407142857142857 0.0124128919860627
TF TF:M04168 Factor: CLOCK; motif: AACACGTGTN 0.000298193132728683 225 10 4 0.4 0.0177777777777778
TF TF:M03975 Factor: ERG; motif: ACCGGAARTN 0.000382488614403173 10002 141 98 0.695035460992908 0.00979804039192162
TF TF:M02059 Factor: ELK-1; motif: ACCGGAAGTN 0.000383989301233639 9423 141 94 0.666666666666667 0.00997559163748275
TF TF:M09765 Factor: SP1; motif: NRGKGGGCGGGGCN 0.00039516026776675 7469 135 77 0.57037037037037 0.0103092783505155
TF TF:M08199_1 Factor: ATF-4:TEF; motif: GGMTGATGCAATM; match class: 1 0.00039516026776675 119 110 7 0.0636363636363636 0.0588235294117647
TF TF:M11396 Factor: Erg; motif: NACCGGAARTN 0.00039516026776675 10765 141 103 0.730496453900709 0.00956804458894566
TF TF:M11530 Factor: E2F-2; motif: NWTTTGGCGCCAWWNN 0.000396367028165611 14593 141 126 0.893617021276596 0.00863427670801069
TF TF:M08913 Factor: FLI-1; motif: NAYTTCCGGT 0.000413932890376623 8322 141 86 0.609929078014184 0.0103340543138669
TF TF:M09868 Factor: ATF-3; motif: GGTSACGTGAN 0.000413932890376623 6391 140 71 0.507142857142857 0.0111093725551557
TF TF:M11603_1 Factor: TCF-1; motif: ACATCGRGRCGCTGW; match class: 1 0.000413932890376623 13184 141 118 0.836879432624113 0.0089502427184466
TF TF:M02062 Factor: Erg; motif: ACCGGAAGTN 0.000418020095142316 8056 139 83 0.597122302158273 0.0103028798411122
TF TF:M03862_1 Factor: YB-1; motif: NNNNCCAATNN; match class: 1 0.000418020095142316 3120 134 42 0.313432835820896 0.0134615384615385
TF TF:M10071 Factor: Sp1; motif: NGGGGGCGGGGCCNGGGGGGGG 0.000424556385674226 8495 135 84 0.622222222222222 0.00988816951147734
TF TF:M11218_1 Factor: CREB1; motif: NRTGAYGCGTN; match class: 1 0.000424556385674226 2438 141 37 0.26241134751773 0.0151763740771124
TF TF:M11435 Factor: Elk-1; motif: NNCCGGAAGTN 0.000425829886699066 11728 141 109 0.773049645390071 0.00929399727148704
TF TF:M03977_1 Factor: ETS1; motif: ACCGGAARYN; match class: 1 0.000430141620417646 4677 140 57 0.407142857142857 0.0121872995509942
TF TF:M11434 Factor: Elk-1; motif: NRSCGGAAGNN 0.00044773153529027 8219 139 84 0.60431654676259 0.0102202214381312
TF TF:M03862 Factor: YB-1; motif: NNNNCCAATNN 0.000449359327666061 9198 141 92 0.652482269503546 0.010002174385736
TF TF:M00981_1 Factor: CREB,; motif: NTGACGTNA; match class: 1 0.000459158223274133 2904 130 39 0.3 0.0134297520661157
TF TF:M11435_1 Factor: Elk-1; motif: NNCCGGAAGTN; match class: 1 0.000459158223274133 5745 141 66 0.468085106382979 0.0114882506527415
TF TF:M03978 Factor: ETS1; motif: GCCGGAWGTACTTCCGGN 0.000478178545179812 12082 141 111 0.787234042553192 0.00918722065883132
TF TF:M11400_1 Factor: Fli-1; motif: NACCGGAARTN; match class: 1 0.000478178545179812 4201 134 51 0.380597014925373 0.0121399666746013
TF TF:M11018 Factor: IRX-1; motif: NACRYNNNNNNNNRYGNN 0.000491716545224447 16955 141 137 0.971631205673759 0.00808021232674727
TF TF:M11404_1 Factor: Fli-1; motif: NACCGGAARTN; match class: 1 0.000552495165198978 3171 134 42 0.313432835820896 0.0132450331125828
TF TF:M00333 Factor: ZF5; motif: NRNGNGCGCGCWN 0.000581612539218689 15072 141 128 0.907801418439716 0.00849256900212314
TF TF:M08224_1 Factor: Elk-1:Pax-1; motif: ACCGGAACTACGCWTSANTG; match class: 1 0.000646899014963991 2748 82 27 0.329268292682927 0.00982532751091703
TF TF:M11530_1 Factor: E2F-2; motif: NWTTTGGCGCCAWWNN; match class: 1 0.000698507791991051 13449 140 118 0.842857142857143 0.00877388653431482
TF TF:M01165 Factor: Elk-1; motif: RACCGGAAGTR 0.000698507791991051 7773 141 81 0.574468085106383 0.0104206869934388
TF TF:M08759 Factor: c-Ets-2; motif: NCCGGAAGTG 0.000698507791991051 8319 141 85 0.602836879432624 0.0102175742276716
TF TF:M11404 Factor: Fli-1; motif: NACCGGAARTN 0.000715064914098004 8743 141 88 0.624113475177305 0.0100651950131534
TF TF:M08377 Factor: meis1:Elf-1; motif: NTGCCGGAAGTN 0.000715064914098004 11275 115 88 0.765217391304348 0.00780487804878049
TF TF:M11018_1 Factor: IRX-1; motif: NACRYNNNNNNNNRYGNN; match class: 1 0.000750326974870785 15920 141 132 0.936170212765957 0.00829145728643216
TF TF:M08523 Factor: E2F-1:TBR2; motif: NGGTGNNANGGCGCNNTNNCRNNN 0.000838067156088258 12160 140 110 0.785714285714286 0.00904605263157895
TF TF:M11309 Factor: ATF-2; motif: NRTGACGTMANN 0.000869936649450974 6429 140 70 0.5 0.0108881630113548
TF TF:M08205 Factor: E2F-1:Elk-1; motif: SGCGCSNNAMCGGAAGT 0.000878108607799736 14429 136 120 0.882352941176471 0.00831658465590131
TF TF:M11221 Factor: CREB1; motif: RTGACGYGTCAN 0.000932512411815981 9677 115 79 0.68695652173913 0.00816368709310737
TF TF:M11428 Factor: PEA3; motif: NACCGGAAGTN 0.00100230229164515 7186 141 76 0.539007092198582 0.0105761202337879
TF TF:M03920 Factor: SP1; motif: RCCMCRCCCMC 0.00100230229164515 7283 135 74 0.548148148148148 0.0101606480845805
TF TF:M08526 Factor: E2F-3:HES-7; motif: NNNSGCGCSNNNNNCRCGYGNN 0.00113078370577832 16867 141 136 0.964539007092199 0.00806308175727752
TF TF:M00695 Factor: ETF; motif: GVGGMGG 0.00113078370577832 10430 141 99 0.702127659574468 0.00949185043144775
TF TF:M11253 Factor: AIBZIP; motif: YGCCACGTCACC 0.00117366505480812 229 129 9 0.0697674418604651 0.0393013100436681
TF TF:M09636_1 Factor: MAZ; motif: GGGMGGGGSSGGGGGGGGGGGG; match class: 1 0.0012047424428469 14096 140 121 0.864285714285714 0.00858399545970488
TF TF:M11427_1 Factor: PEA3; motif: NACCGGAAGTN; match class: 1 0.00121482034320737 4606 131 52 0.396946564885496 0.0112896222318715
TF TF:M00177 Factor: CREB; motif: NSTGACGTAANN 0.00122152378676832 5221 70 35 0.5 0.00670369660984486
TF TF:M02090 Factor: E2F-4; motif: GCGGGAAANA 0.00122152378676832 11966 111 88 0.792792792792793 0.00735417014875481
TF TF:M03924_1 Factor: YY1; motif: NNCGCCATTNN; match class: 1 0.00122152378676832 3700 98 36 0.36734693877551 0.00972972972972973
TF TF:M00932 Factor: Sp1; motif: NNGGGGCGGGGNN 0.00127437970199515 10419 135 95 0.703703703703704 0.00911795757750264
TF TF:M10849_1 Factor: Cdx-2; motif: NRTCGTAANNNN; match class: 1 0.00134676961585385 4497 118 47 0.398305084745763 0.0104514120524794
TF TF:M07380 Factor: E2F-4; motif: NTTTCSCGCC 0.00141755303965378 13022 138 113 0.818840579710145 0.00867762248502534
TF TF:M02052 Factor: EHF; motif: CSCGGAARTN 0.00159710748498632 10107 139 95 0.683453237410072 0.0093994261402988
TF TF:M00114 Factor: Tax/CREB; motif: GGGGGTTGACGYANA 0.00159710748498632 6548 133 67 0.503759398496241 0.0102321319486866
TF TF:M00287 Factor: NF-Y; motif: NNNRRCCAATSRGNNN 0.00159710748498632 1635 75 18 0.24 0.0110091743119266
TF TF:M08525_1 Factor: E2F-1:HES-7; motif: GGCRCGTGSYNNWNGGCGCSM; match class: 1 0.00159710748498632 15268 140 127 0.907142857142857 0.00831805082525544
TF TF:M03544 Factor: CREB1; motif: NNNNACGTCANN 0.00159710748498632 4101 140 50 0.357142857142857 0.0121921482565228
TF TF:M03990 Factor: GABPA; motif: ACCGGAAGTN 0.00159710748498632 5258 135 58 0.42962962962963 0.0110308101939901
TF TF:M11425 Factor: PEA3; motif: NACCGGAAGTN 0.00159710748498632 7428 141 77 0.546099290780142 0.0103661820140011
TF TF:M00652 Factor: NRF-1; motif: CGCATGCGCR 0.0016340871504992 1376 139 24 0.172661870503597 0.0174418604651163
TF TF:M11400 Factor: Fli-1; motif: NACCGGAARTN 0.00165299310204375 9946 141 95 0.673758865248227 0.00955157852402976
TF TF:M11433_1 Factor: Elk-1; motif: NRCCGGAAGTN; match class: 1 0.00168368589446159 2261 139 33 0.237410071942446 0.0145953118089341
TF TF:M00738 Factor: E2F-4:DP-1; motif: TTTSGCGC 0.00168531603273559 9812 141 94 0.666666666666667 0.00958010599266205
TF TF:M04748_1 Factor: GABP-alpha; motif: AACCGGAAR; match class: 1 0.00168531603273559 10368 138 96 0.695652173913043 0.00925925925925926
TF TF:M08266_1 Factor: ER71:Pax-5; motif: ACCGGAACYACGCWTSANTG; match class: 1 0.00168531603273559 8979 137 86 0.627737226277372 0.00957790399821806
TF TF:M03567 Factor: Sp2; motif: NYSGCCCCGCCCCCY 0.00168531603273559 7710 139 78 0.561151079136691 0.0101167315175097
TF TF:M04515 Factor: E2F-1; motif: WWTGGCGCCAAA 0.00170158594123306 13334 140 116 0.828571428571429 0.00869956502174891
TF TF:M10006 Factor: NF-YC; motif: NNRRCCAATCAGNR 0.00171635455428558 2510 75 23 0.306666666666667 0.00916334661354582
TF TF:M07250 Factor: E2F-1; motif: NNNSSCGCSAANN 0.0017220265178897 10703 141 100 0.709219858156028 0.00934317481080071
TF TF:M09905 Factor: SAP-1; motif: NNCCGGAAGTGN 0.00172282502188236 8273 141 83 0.588652482269504 0.0100326362867158
TF TF:M00025 Factor: Elk-1; motif: NNNNCCGGAARTNN 0.00172361862437671 10262 141 97 0.687943262411348 0.0094523484700838
TF TF:M08225_1 Factor: Elk-1:Pax-5; motif: ACCGGAACYACGCWTSANYG; match class: 1 0.00172361862437671 7993 135 78 0.577777777777778 0.00975853872138121
TF TF:M02063 Factor: c-ets-1; motif: ACCGGAWGTN 0.00172896604625631 7600 141 78 0.553191489361702 0.0102631578947368
TF TF:M00740 Factor: Rb:E2F-1:DP-1; motif: TTTSGCGC 0.00184630738561341 10427 141 98 0.695035460992908 0.0093986765128992
TF TF:M03982 Factor: ETV4; motif: ACCGGAAGTN 0.00188637002167567 6826 141 72 0.51063829787234 0.0105479050688544
TF TF:M07129 Factor: Sp2; motif: GYCCCGCCYCYNNNN 0.00190355806998527 6260 137 66 0.481751824817518 0.0105431309904153
TF TF:M09636 Factor: MAZ; motif: GGGMGGGGSSGGGGGGGGGGGG 0.00190355806998527 16244 109 104 0.954128440366973 0.00640236394976607
TF TF:M11419 Factor: ER81; motif: NNCCGGAWGYN 0.00208414951205875 5699 141 63 0.446808510638298 0.0110545709773644
TF TF:M00428 Factor: E2F-1; motif: NKTSSCGC 0.00209437468054118 8947 116 74 0.637931034482759 0.00827092880295071
TF TF:M10578 Factor: Barhl-1; motif: NTAAACGN 0.00209437468054118 6099 120 58 0.483333333333333 0.00950975569765535
TF TF:M02061 Factor: ERF; motif: ACCGGAARYN 0.00210840739781918 2579 141 36 0.25531914893617 0.0139588987979837
TF TF:M01660 Factor: GABP-alpha; motif: CTTCCK 0.00221092422481358 11116 139 101 0.726618705035971 0.00908600215905002
TF TF:M00916_1 Factor: CREB; motif: NNTKACGTCANNNS; match class: 1 0.00224357508631685 1692 140 27 0.192857142857143 0.0159574468085106
TF TF:M11382 Factor: ESE-1; motif: NWTRCGGAWGCN 0.00231364731845792 10339 141 97 0.687943262411348 0.00938195183286585
TF TF:M08226 Factor: Elk-1:Pax-9; motif: ACCGGAACYACGCWYSANTG 0.00241807232993189 12039 135 104 0.77037037037037 0.00863859124512003
TF TF:M02069 Factor: Erm; motif: ACCGGAAGTN 0.00249827043473951 6892 141 72 0.51063829787234 0.0104468949506674
TF TF:M11447 Factor: Elf-1; motif: NAMCCGGAAGTN 0.0026809361808617 7703 141 78 0.553191489361702 0.0101259249642996
TF TF:M00940 Factor: E2F-1; motif: NTTTCGCGCS 0.0026809361808617 7802 100 59 0.59 0.00756216354780825
TF TF:M00178 Factor: CREB; motif: NSTGACGTMANN 0.00271999168919762 5255 78 37 0.474358974358974 0.00704091341579448
TF TF:M02107 Factor: NF-YC; motif: NRGCCAATYAGMGC 0.00283176096208897 1001 115 17 0.147826086956522 0.016983016983017
TF TF:M07302 Factor: NF-Y; motif: RGCCAATCRGN 0.00284620548827817 1576 75 17 0.226666666666667 0.0107868020304569
TF TF:M01752_1 Factor: ERG; motif: ACCGGAART; match class: 1 0.00289827142534042 3705 134 44 0.328358208955224 0.0118758434547908
TF TF:M11392_1 Factor: Erg; motif: NACCGGAARYN; match class: 1 0.00289827142534042 3233 134 40 0.298507462686567 0.0123724095267553
TF TF:M07395_1 Factor: Sp1; motif: NGGGGCGGGGN; match class: 1 0.00292896479718277 6334 135 65 0.481481481481481 0.0102620776760341
TF TF:M03807 Factor: SP2; motif: GNNGGGGGCGGGGSN 0.00292896479718277 8415 135 80 0.592592592592593 0.0095068330362448
TF TF:M00338 Factor: ATF; motif: NTGACGTCANYS 0.00297551018820158 3798 139 46 0.330935251798561 0.0121116377040548
TF TF:M02071 Factor: ETV7; motif: NCCGGAANNN 0.00299150551035165 10116 141 95 0.673758865248227 0.0093910636615263
TF TF:M00017_1 Factor: ATF; motif: CNSTGACGTNNNYC; match class: 1 0.00316647431808683 2222 135 31 0.22962962962963 0.013951395139514
TF TF:M00986 Factor: Churchill; motif: CGGGNN 0.0031913788396494 14197 111 97 0.873873873873874 0.0068324293864901
TF TF:M09904 Factor: Elk-1; motif: RCCGGAAGTGN 0.00326668996122461 8164 141 81 0.574468085106383 0.00992160705536502
TF TF:M11217 Factor: CREB1; motif: NRTGACGYN 0.00340401324963601 2783 140 37 0.264285714285714 0.0132950053898671
TF TF:M04823 Factor: E2F-4; motif: NNTTCCCGCCNN 0.0034996546915273 12747 89 74 0.831460674157303 0.00580528751863183
TF TF:M02090_1 Factor: E2F-4; motif: GCGGGAAANA; match class: 1 0.00365764671344499 6378 86 45 0.523255813953488 0.0070555032925682
TF TF:M11219 Factor: CREB1; motif: NRTGACGTR 0.00372358710788629 873 135 17 0.125925925925926 0.0194730813287514
TF TF:M08207 Factor: E2F-3:TBR2; motif: ANGTGYKANGGCGCSTTNNCRNNT 0.00372358710788629 17055 137 132 0.963503649635037 0.00773966578715919
TF TF:M11877_1 Factor: pax-2; motif: NCGTCACGCNYSRNYGCNYN; match class: 1 0.00379065461552032 5304 133 56 0.421052631578947 0.0105580693815988
TF TF:M11533_1 Factor: E2F-1; motif: NTTTTGGCGCCAWWWN; match class: 1 0.00379065461552032 8705 134 81 0.604477611940298 0.00930499712808731
TF TF:M02062_1 Factor: Erg; motif: ACCGGAAGTN; match class: 1 0.00386000179173793 2718 139 36 0.258992805755396 0.0132450331125828
TF TF:M01240 Factor: BEN; motif: CAGCGRNV 0.00392052246287144 16498 141 133 0.943262411347518 0.00806158322220875
TF TF:M11528_1 Factor: E2F-2; motif: NTTTTGGCGCCAWWWN; match class: 1 0.00393695153781105 4778 140 54 0.385714285714286 0.011301799916283
TF TF:M10436 Factor: YY1; motif: CAANATGGCGGC 0.00393695153781105 8220 97 59 0.608247422680412 0.00717761557177616
TF TF:M01783 Factor: SP2; motif: GGGCGGGAC 0.00393695153781105 9148 80 54 0.675 0.00590292960209882
TF TF:M11433 Factor: Elk-1; motif: NRCCGGAAGTN 0.00398533974639254 7679 141 77 0.546099290780142 0.0100273473108478
TF TF:M03988_1 Factor: FLI1; motif: ACCGGAARTN; match class: 1 0.00398533974639254 2950 134 37 0.276119402985075 0.0125423728813559
TF TF:M08457_1 Factor: ER71:SREBP-2; motif: NTSACGTGACGGAARY; match class: 1 0.00420217245553992 5591 108 49 0.453703703703704 0.00876408513682704
TF TF:M04197_1 Factor: ATF4; motif: NNATGAYGCAATM; match class: 1 0.00421250404213287 197 110 7 0.0636363636363636 0.0355329949238579
TF TF:M00113_1 Factor: CREB; motif: NNGNTGACGTNN; match class: 1 0.0042955366068884 869 125 16 0.128 0.0184119677790564
TF TF:M03925 Factor: YY2; motif: NCCGCCATNTY 0.0043038026295422 4641 141 53 0.375886524822695 0.0114199525964232
TF TF:M11601_1 Factor: TCF-1; motif: ACATCGRGRCGCTGW; match class: 1 0.00441906194021712 11053 112 82 0.732142857142857 0.00741880032570343
TF TF:M02052_1 Factor: EHF; motif: CSCGGAARTN; match class: 1 0.00447028780074917 4056 141 48 0.340425531914894 0.0118343195266272
TF TF:M01163 Factor: Elk-1; motif: AACCGGAAGTR 0.00448410755072221 5260 141 58 0.411347517730496 0.0110266159695817
TF TF:M11877 Factor: pax-2; motif: NCGTCACGCNYSRNYGCNYN 0.00449792830981379 11523 140 103 0.735714285714286 0.00893864445022998
TF TF:M00341 Factor: GABP; motif: VCCGGAAGNGCR 0.00453836755112156 8224 78 49 0.628205128205128 0.00595817120622568
TF TF:M11410 Factor: etv3; motif: NNCGGAARTGSCAYTTCCGNT 0.00459794691499397 1044 139 19 0.136690647482014 0.0181992337164751
TF TF:M08451 Factor: Elk-1:HOXA1; motif: ACCGGAAGTAATTA 0.0050439072440136 8421 139 81 0.58273381294964 0.00961881011756324
TF TF:M04515_1 Factor: E2F-1; motif: WWTGGCGCCAAA; match class: 1 0.0050439072440136 12173 140 107 0.764285714285714 0.00878994496015773
TF TF:M11603 Factor: TCF-1; motif: ACATCGRGRCGCTGW 0.005146216986874 16361 141 132 0.936170212765957 0.00806796650571481
TF TF:M00032_1 Factor: c-Ets-1(p54); motif: NCMGGAWGYN; match class: 1 0.00522491203721405 2161 49 15 0.306122448979592 0.00694123091161499
TF TF:M00803 Factor: E2F; motif: GGCGSG 0.00529948146884516 13190 141 114 0.808510638297872 0.00864291129643669
TF TF:M00687 Factor: alpha-CP1; motif: CAGCCAATGAG 0.00529948146884516 2326 140 32 0.228571428571429 0.0137575236457438
TF TF:M09970 Factor: KLF3; motif: NNNNNNGGGCGGGGCNNGN 0.00529948146884516 7728 135 74 0.548148148148148 0.00957556935817805
TF TF:M00737 Factor: E2F-1:DP-2; motif: TTTSSCGC 0.00549001261687235 8771 125 76 0.608 0.00866491848135902
TF TF:M04710 Factor: CHD2; motif: TCTCGCGAG 0.00549001261687235 14109 134 114 0.850746268656716 0.00807994896874335
TF TF:M01864 Factor: ATF-4; motif: KACGTCAKS 0.00552234869628975 4477 137 50 0.364963503649635 0.0111681929863748
TF TF:M11230 Factor: CREBL1; motif: YGCCACGTCAYC 0.00553753291651783 56 98 4 0.0408163265306122 0.0714285714285714
TF TF:M08266 Factor: ER71:Pax-5; motif: ACCGGAACYACGCWTSANTG 0.0057130839847078 14377 141 121 0.858156028368794 0.00841622035195103
TF TF:M00425 Factor: E2F; motif: TTTCGCGC 0.00581263753390091 11043 141 100 0.709219858156028 0.00905551027800417
TF TF:M07409 Factor: BTEB2; motif: GCCCCRCCCH 0.0058557505077514 5198 135 55 0.407407407407407 0.010580992689496
TF TF:M02075 Factor: PDEF; motif: MCCGGATNTN 0.00586033011431683 2666 140 35 0.25 0.0131282820705176
TF TF:M00917_1 Factor: CREB; motif: CNNTGACGTMA; match class: 1 0.00587351520075065 1590 135 24 0.177777777777778 0.0150943396226415
TF TF:M03805_1 Factor: YB-1; motif: CCAMTCNGMR; match class: 1 0.00587351520075065 3680 77 28 0.363636363636364 0.00760869565217391
TF TF:M08390 Factor: A-Myb:Elf-1; motif: NMCCGGAACCGTTA 0.00589105135615561 11072 122 88 0.721311475409836 0.00794797687861272
TF TF:M12351 Factor: TIEG1; motif: NCCCNSNCCCCGCCCCC 0.00589105135615561 12302 135 104 0.77037037037037 0.00845390993334417
TF TF:M00123_1 Factor: c-Myc:Max; motif: NANCACGTGNNW; match class: 1 0.00589105135615561 635 10 4 0.4 0.0062992125984252
TF TF:M10785_1 Factor: hoxa9; motif: RTCGTWANNN; match class: 1 0.00593919708000857 1160 70 13 0.185714285714286 0.0112068965517241
TF TF:M07615 Factor: Sp3; motif: GGGGCGGGGSNN 0.00616209331997266 6807 135 67 0.496296296296296 0.00984280887321875
TF TF:M11420 Factor: ER81; motif: NACCGGAAGTN 0.00616209331997266 3210 39 16 0.41025641025641 0.00498442367601246
TF TF:M11488 Factor: CP2; motif: WACCGGTTNNAACCGGWT 0.00640357827958998 3424 133 40 0.300751879699248 0.0116822429906542
TF TF:M03971 Factor: ELK1; motif: NACTTCCGSCGGAAGYN 0.00671714667472676 11293 125 91 0.728 0.00805808908173205
TF TF:M09954_1 Factor: HOXB4; motif: YTAATGRC; match class: 1 0.00672097663535765 139 78 5 0.0641025641025641 0.0359712230215827
TF TF:M00775 Factor: NF-Y; motif: NNNNRRCCAATSR 0.00724419768433852 1428 134 22 0.164179104477612 0.015406162464986
TF TF:M03924 Factor: YY1; motif: NNCGCCATTNN 0.00738688188160322 10084 141 93 0.659574468085106 0.00922253074176914
TF TF:M11381 Factor: ESE-1; motif: SATKGCGGATGCN 0.00740312667507027 15720 121 111 0.917355371900826 0.00706106870229008
TF TF:M00333_1 Factor: ZF5; motif: NRNGNGCGCGCWN; match class: 1 0.0074901178983147 12401 139 107 0.76978417266187 0.0086283364244819
TF TF:M11081 Factor: SREBP-1; motif: RTCRCGTGAY 0.00777169626387096 11062 115 83 0.721739130434783 0.00750316398481287
TF TF:M02053 Factor: ELF1; motif: NCCGGAARTN 0.00810634458234646 6033 141 63 0.446808510638298 0.0104425658876181
TF TF:M11090 Factor: TFEA; motif: YRCACGTGACN 0.00857796677093201 6189 7 7 1 0.00113103894005494
TF TF:M08313_1 Factor: GCMa:PEA3; motif: ATRCGGGCGGAAGTR; match class: 1 0.0088909827678744 9721 139 89 0.640287769784173 0.00915543668346878
TF TF:M08875 Factor: E2F; motif: NNTTTCGCGCN 0.0088909827678744 6203 112 53 0.473214285714286 0.00854425278091246
TF TF:M03830 Factor: MafB; motif: CRCTGACNANN 0.00926382448729164 7236 141 72 0.51063829787234 0.00995024875621891
TF TF:M04059 Factor: NRF-1; motif: YGCGCATGCGCN 0.00927095075732365 1471 133 22 0.165413533834586 0.0149558123725357
TF TF:M11417_1 Factor: c-Ets-2; motif: NACCGGAAGYRCTTCCGGTN; match class: 1 0.00927095075732365 14041 124 105 0.846774193548387 0.007478099850438
TF TF:M00695_1 Factor: ETF; motif: GVGGMGG; match class: 1 0.00929297395024442 7032 140 70 0.5 0.00995449374288965
TF TF:M10102 Factor: THAP11; motif: KGCMTKCTGGGARTTGTAGTYY 0.00929297395024442 378 138 10 0.072463768115942 0.0264550264550265
TF TF:M01861_1 Factor: ATF-1; motif: TNACGTCAN; match class: 1 0.00934866317717476 1896 140 27 0.192857142857143 0.0142405063291139
TF TF:M02073 Factor: Fli-1; motif: ACCGGAAGYN 0.00934866317717476 5839 135 59 0.437037037037037 0.0101044699434835
TF TF:M00008 Factor: Sp1; motif: GGGGCGGGGT 0.00934866317717476 10055 137 90 0.656934306569343 0.00895077076081552
TF TF:M11601 Factor: TCF-1; motif: ACATCGRGRCGCTGW 0.00964452981208526 14823 118 104 0.88135593220339 0.00701612359171558
TF TF:M08229_1 Factor: Elk-1:SREBP-2; motif: RTCACGTGACCGGAAGN; match class: 1 0.0097725470715118 3095 42 16 0.380952380952381 0.00516962843295638
TF TF:M03566 Factor: SNA; motif: GCCACCTGNCNGYN 0.0097725470715118 2260 72 19 0.263888888888889 0.0084070796460177
TF TF:M02059_1 Factor: ELK-1; motif: ACCGGAAGTN; match class: 1 0.00981241853768114 3759 141 44 0.312056737588652 0.0117052407555201
TF TF:M08664_1 Factor: AP-2gamma:Max; motif: NNSCCYNRGGSNNNNCACGTGN; match class: 1 0.00990364424013129 260 132 8 0.0606060606060606 0.0307692307692308
TF TF:M04714 Factor: Elf-1; motif: ACTTCCGGG 0.00992687130285166 7798 141 76 0.539007092198582 0.00974608874070274
TF TF:M08377_1 Factor: meis1:Elf-1; motif: NTGCCGGAAGTN; match class: 1 0.00995304048868403 5051 120 48 0.4 0.00950306869926747
TF TF:M08214_1 Factor: Elk-1:ETV7; motif: ANSCGGACGGATDTCCGGNT; match class: 1 0.00998018227930648 2312 7 5 0.714285714285714 0.00216262975778547
TF TF:M02070_1 Factor: TEL1; motif: CNCGGAANNN; match class: 1 0.00998018227930648 4841 141 53 0.375886524822695 0.010948151208428
TF TF:M01820_1 Factor: CREM; motif: TGACGTCASYN; match class: 1 0.0101709961619967 1879 135 26 0.192592592592593 0.0138371474188398
TF TF:M05439 Factor: RREB-1; motif: GGGWCSA 0.0103026950266471 8635 137 80 0.583941605839416 0.00926462072958888
TF TF:M02074 Factor: GABPalpha; motif: RCCGGAWRYN 0.0103798165033392 4607 141 51 0.361702127659574 0.011070110701107
TF TF:M04106_1 Factor: RUNX2; motif: NRACCGCAAACCGCAN; match class: 1 0.0110242463048468 8372 141 80 0.567375886524823 0.00955566172957477
TF TF:M12160 Factor: KLF15; motif: RCCMCRCCCMCN 0.011472769874549 12729 140 109 0.778571428571429 0.0085631235760861
TF TF:M08313 Factor: GCMa:PEA3; motif: ATRCGGGCGGAAGTR 0.011569669898019 15419 134 120 0.895522388059702 0.00778260587586744
TF TF:M00803_1 Factor: E2F; motif: GGCGSG; match class: 1 0.0120732869760351 10230 141 93 0.659574468085106 0.00909090909090909
TF TF:M08226_1 Factor: Elk-1:Pax-9; motif: ACCGGAACYACGCWYSANTG; match class: 1 0.0120732869760351 5604 99 44 0.444444444444444 0.00785153461812991
TF TF:M11432 Factor: Elk-1; motif: NACMGGAAGTN 0.0120732869760351 6140 141 63 0.446808510638298 0.0102605863192182
TF TF:M11533 Factor: E2F-1; motif: NTTTTGGCGCCAWWWN 0.0120732869760351 13105 141 112 0.794326241134752 0.0085463563525372
TF TF:M01660_1 Factor: GABP-alpha; motif: CTTCCK; match class: 1 0.0121477384418808 5133 141 55 0.390070921985816 0.0107149814923047
TF TF:M00539 Factor: Arnt; motif: NNNNNRTCACGTGAYNNNNN 0.012569643091475 6676 7 7 1 0.00104853205512283
TF TF:M00539_1 Factor: Arnt; motif: NNNNNRTCACGTGAYNNNNN; match class: 1 0.012569643091475 6676 7 7 1 0.00104853205512283
TF TF:M11417 Factor: c-Ets-2; motif: NACCGGAAGYRCTTCCGGTN 0.012569643091475 14334 124 106 0.854838709677419 0.00739500488349379
TF TF:M07063 Factor: Sp1; motif: GGGGCGGGGC 0.012569643091475 7696 135 72 0.533333333333333 0.00935550935550936
TF TF:M10435 Factor: Sp2; motif: GGGGCGGGG 0.012569643091475 7696 135 72 0.533333333333333 0.00935550935550936
TF TF:M00055 Factor: N-Myc; motif: NNCCACGTGNNN 0.012569643091475 4167 7 6 0.857142857142857 0.00143988480921526
TF TF:M08225 Factor: Elk-1:Pax-5; motif: ACCGGAACYACGCWTSANYG 0.0126424047314469 14039 135 113 0.837037037037037 0.00804900633948287
TF TF:M00024 Factor: E2F-1; motif: TWSGCGCGAAAAYKR 0.0126624705085136 8919 115 70 0.608695652173913 0.00784841349927122
TF TF:M02070 Factor: TEL1; motif: CNCGGAANNN 0.0127175850930545 10837 141 97 0.687943262411348 0.00895081664667343
TF TF:M07617 Factor: Sp4; motif: SCCCCKCCCCCSN 0.0127175850930545 3595 56 21 0.375 0.00584144645340751
TF TF:M03983 Factor: ETV5; motif: NCCGGAWGYN 0.0127175850930545 3129 141 38 0.269503546099291 0.0121444550974752
TF TF:M04516 Factor: E2F-1; motif: TTTGGCGCCAAA 0.0128633655540475 11383 140 100 0.714285714285714 0.00878503030835456
TF TF:M12151 Factor: Sp1; motif: NWRGCCMCGCCCMCN 0.0128633655540475 6821 136 66 0.485294117647059 0.00967600058642428
TF TF:M00008_1 Factor: Sp1; motif: GGGGCGGGGT; match class: 1 0.0128633655540475 4937 137 52 0.37956204379562 0.0105327121733846
TF TF:M04287 Factor: BARHL2; motif: NNTAAAYGNN 0.0129411599093529 4416 120 43 0.358333333333333 0.00973731884057971
TF TF:M09600 Factor: CREB1; motif: TKACGTCAYNN 0.0130174874863482 5324 140 56 0.4 0.0105184072126221
TF TF:M00114_1 Factor: Tax/CREB; motif: GGGGGTTGACGYANA; match class: 1 0.013112504073644 1564 130 22 0.169230769230769 0.0140664961636829
TF TF:M10919 Factor: Otx3; motif: NTAATCCN 0.0131441180950687 850 118 14 0.11864406779661 0.0164705882352941
TF TF:M10129 Factor: Staf; motif: NGCMTKCTGGGARWTGTAGTYY 0.0131441180950687 479 138 11 0.0797101449275362 0.022964509394572
TF TF:M02102 Factor: NRF-1; motif: YGCGCMTGCGC 0.0131668777571654 2020 129 26 0.201550387596899 0.0128712871287129
TF TF:M11309_1 Factor: ATF-2; motif: NRTGACGTMANN; match class: 1 0.0131668777571654 2293 139 30 0.215827338129496 0.0130832969908417
TF TF:M03806 Factor: ZBTB7C; motif: GKCCCGGGCKG 0.0132806187797347 3031 141 37 0.26241134751773 0.0122071923457605
TF TF:M03893 Factor: WT1; motif: GNGGGGGCGGGG 0.0132806187797347 8290 133 75 0.56390977443609 0.00904704463208685
TF TF:M09967 Factor: AP-2rep; motif: NGGGGCGGGGC 0.0132806187797347 4023 135 44 0.325925925925926 0.0109371116082525
TF TF:M00971 Factor: Ets; motif: ACTTCCTS 0.0132806187797347 2349 31 11 0.354838709677419 0.00468284376330353
TF TF:M09892 Factor: E2F-1; motif: NNNNGGCGGGAARN 0.0132806187797347 13528 89 75 0.842696629213483 0.00554405677114134
TF TF:M02067_1 Factor: ER71; motif: ACCGGAARYN; match class: 1 0.0132806187797347 1619 110 20 0.181818181818182 0.0123533045089561
TF TF:M04059_1 Factor: NRF-1; motif: YGCGCATGCGCN; match class: 1 0.0133256865293604 1033 133 17 0.12781954887218 0.0164569215876089
TF TF:M11424_1 Factor: Erm; motif: NNSCGGAWGYN; match class: 1 0.0133256865293604 2835 104 28 0.269230769230769 0.00987654320987654
TF TF:M00327 Factor: Pax-3; motif: NNNNNNCGTCACGSTYNNNNN 0.0134336116525494 13318 141 113 0.801418439716312 0.00848475747109175
TF TF:M04518 Factor: E2F-4; motif: AATGGCGCCAAA 0.0134336116525494 5521 130 54 0.415384615384615 0.00978083680492664
TF TF:M11419_1 Factor: ER81; motif: NNCCGGAWGYN; match class: 1 0.0138053789699744 1427 49 11 0.224489795918367 0.00770847932725999
TF TF:M03805 Factor: YB-1; motif: CCAMTCNGMR 0.0138566707736935 10161 134 88 0.656716417910448 0.00866056490502903
TF TF:M11218 Factor: CREB1; motif: NRTGAYGCGTN 0.0139438221417776 8461 141 80 0.567375886524823 0.00945514714572745
TF TF:M11882_1 Factor: pax-6; motif: NYACGCNYSANYGMNCN; match class: 1 0.0140141987327822 11423 140 100 0.714285714285714 0.00875426770550643
TF TF:M10018 Factor: NRF-1; motif: CNSTGCGCATGCGCNNS 0.0144598228990117 1816 129 24 0.186046511627907 0.013215859030837
TF TF:M07380_1 Factor: E2F-4; motif: NTTTCSCGCC; match class: 1 0.0144598228990117 7965 134 73 0.544776119402985 0.00916509730069052
TF TF:M00678 Factor: Tel-2; motif: YTACTTCCTG 0.0149600976015056 5292 33 18 0.545454545454545 0.00340136054421769
TF TF:M01214_1 Factor: ESE-1; motif: NSMGGAARTN; match class: 1 0.015514842501902 2176 39 12 0.307692307692308 0.00551470588235294
TF TF:M02055_1 Factor: ESE-1; motif: NSMGGAARTN; match class: 1 0.015514842501902 2176 39 12 0.307692307692308 0.00551470588235294
TF TF:M00262 Factor: Staf; motif: NTTWCCCANMATGCAYYRCGNY 0.015543324510222 1301 118 18 0.152542372881356 0.0138355111452729
TF TF:M00245 Factor: Egr-3; motif: NTGCGTGGGCGK 0.0158664372588297 7313 22 16 0.727272727272727 0.00218788458908793
TF TF:M09994 Factor: Myogenin; motif: NNNCAGCTGYYNN 0.0167135948348947 630 48 7 0.145833333333333 0.0111111111111111
TF TF:M01588 Factor: GKLF; motif: GCCMCRCCCNNN 0.0167333579075951 8944 135 80 0.592592592592593 0.00894454382826476
TF TF:M09826 Factor: BTEB3; motif: CCNNSCCNSCCCCKCCCCC 0.0168079377813587 11467 137 98 0.715328467153285 0.00854626319002355
TF TF:M12153 Factor: Sp3; motif: NGCCACGCCCMCN 0.0168079377813587 6205 77 38 0.493506493506494 0.00612409347300564
TF TF:M03895 Factor: CTCF; motif: WGCGCCMYCTAGYGGYN 0.0169814332042264 9251 98 62 0.63265306122449 0.00670197816452275
TF TF:M12156 Factor: Sp2; motif: NTAAGYCCCGCCCMCTN 0.0170223644176458 4320 139 47 0.338129496402878 0.0108796296296296
TF TF:M11535 Factor: E2F-4; motif: TTTTGGCGCCAWWN 0.0170629416293599 10884 140 96 0.685714285714286 0.00882028665931643
TF TF:M08441_1 Factor: AP-2gamma:Elk-1; motif: NGCCKNRGGSGRCGGAAGTG; match class: 1 0.0172480165991427 12761 141 109 0.773049645390071 0.00854165034088238
TF TF:M04710_1 Factor: CHD2; motif: TCTCGCGAG; match class: 1 0.0172480165991427 11477 137 98 0.715328467153285 0.00853881676396271
TF TF:M09868_1 Factor: ATF-3; motif: GGTSACGTGAN; match class: 1 0.0176367473682263 2116 140 28 0.2 0.0132325141776938
TF TF:M08213 Factor: Elk-1:TBR2; motif: TNRCACCGGAAGN 0.0181024209144332 6273 133 60 0.451127819548872 0.00956480153036825
TF TF:M02068 Factor: etv3; motif: ACCGGAAGYN 0.018246092781988 3443 141 40 0.283687943262411 0.01161777519605
TF TF:M04448 Factor: VENTX; motif: ANCGATTAR 0.018246092781988 419 94 8 0.0851063829787234 0.0190930787589499
TF TF:M09732 Factor: RFX3; motif: NYNCCMTGGCAACM 0.0182487266385414 5207 34 18 0.529411764705882 0.00345688496255041
TF TF:M00736_1 Factor: E2F-1:DP-1; motif: TTTCSCGC; match class: 1 0.0182487266385414 4639 107 40 0.373831775700935 0.00862254796292304
TF TF:M11271 Factor: JunD; motif: NRTGACGCAYN 0.0184124798955556 7009 130 64 0.492307692307692 0.009131117135112
TF TF:M08246 Factor: ER71:C/EBPdelta; motif: NNCGGAWRTTRCGYAAN 0.0184124798955556 8387 93 55 0.591397849462366 0.00655776797424586
TF TF:M00651 Factor: NF-muE1; motif: CGGCCATCT 0.0185883771607785 257 86 6 0.0697674418604651 0.0233463035019455
TF TF:M08232_1 Factor: Elk-1:TEF; motif: RCCGGAAGTTACGTAAN; match class: 1 0.0185901539422334 1294 92 15 0.16304347826087 0.0115919629057187
TF TF:M08418 Factor: TEF-3:Elk-1; motif: RMATWCCGGAWGT 0.0187783713098288 11758 121 89 0.735537190082645 0.00756931450927028
TF TF:M04869_1 Factor: Egr-1; motif: GCGCATGCG; match class: 1 0.0187783713098288 10253 107 72 0.672897196261682 0.00702233492636302
TF TF:M04519_1 Factor: E2F-4; motif: TTTGGCGCCAAA; match class: 1 0.0187783713098288 2547 141 32 0.226950354609929 0.0125638005496663
TF TF:M04869 Factor: Egr-1; motif: GCGCATGCG 0.01900164303408 11232 107 77 0.719626168224299 0.00685541310541311
TF TF:M00427 Factor: E2F; motif: TTTSGCGS 0.0192046558134874 9485 100 64 0.64 0.00674749604638904
TF TF:M09816 Factor: NFYA; motif: RRCCAATCAGN 0.0192046558134874 1969 75 17 0.226666666666667 0.00863382427628238
TF TF:M09608 Factor: Erg; motif: NNACCGGAARTSN 0.0192046558134874 8152 141 77 0.546099290780142 0.00944553483807655
TF TF:M02071_1 Factor: ETV7; motif: NCCGGAANNN; match class: 1 0.0197290955135837 4465 39 18 0.461538461538462 0.00403135498320269
TF TF:M08913_1 Factor: FLI-1; motif: NAYTTCCGGT; match class: 1 0.0198535725448934 3055 134 35 0.261194029850746 0.0114566284779051
TF TF:M12158 Factor: KLF15; motif: NCCMCGCCCMCN 0.0198535725448934 11088 140 97 0.692857142857143 0.00874819624819625
TF TF:M11531_1 Factor: E2F-2; motif: GCGCGCGCGYW; match class: 1 0.0202354471533569 12351 71 57 0.802816901408451 0.00461501093028905
TF TF:M00246 Factor: Egr-2; motif: NTGCGTRGGCGK 0.0202354471533569 6212 32 19 0.59375 0.00305859626529298
TF TF:M07084 Factor: E2F-4; motif: NGGCGGGAARN 0.0202743071778094 10834 125 86 0.688 0.00793797304781244
TF TF:M12231 Factor: LRF; motif: NCGACCACCGN 0.0205048737578892 11477 133 95 0.714285714285714 0.00827742441404548
TF TF:M12345 Factor: Zbtb37; motif: NYACCGCRNTCACCGCR 0.0206044200810253 5505 139 56 0.402877697841727 0.010172570390554
TF TF:M04932 Factor: Sp2; motif: AAGGGGCGG 0.0206044200810253 2593 134 31 0.23134328358209 0.0119552641727729
TF TF:M02067 Factor: ER71; motif: ACCGGAARYN 0.0206820408646092 5930 141 60 0.425531914893617 0.0101180438448567
TF TF:M00209 Factor: NF-Y; motif: NCTGATTGGYTASY 0.0209334727457194 3776 75 26 0.346666666666667 0.00688559322033898
TF TF:M01876 Factor: GABP-beta; motif: ASMGGAAGKGN 0.0211106300232369 2138 141 28 0.198581560283688 0.0130963517305893
TF TF:M10634 Factor: Nkx2-3; motif: NSCACTTNNC 0.0211709723214106 2644 14 7 0.5 0.00264750378214826
TF TF:M03922 Factor: SP4; motif: NWRGCCACGCCCMCTYN 0.0212206069682616 6046 136 59 0.433823529411765 0.00975851802844856
TF TF:M00039_1 Factor: CREB; motif: TGACGTMA; match class: 1 0.0212206069682616 1482 135 21 0.155555555555556 0.01417004048583
TF TF:M01208 Factor: FLI-1; motif: CMGGAWGTSAN 0.0217677987617459 6232 39 22 0.564102564102564 0.00353016688061617
TF TF:M07415_1 Factor: Elf-1; motif: AWCCCGGAAGTN; match class: 1 0.0218000665656537 2397 139 30 0.215827338129496 0.0125156445556946
TF TF:M03791_1 Factor: GABPalpha_GABPbeta; motif: CTTCCKGY; match class: 1 0.0218377999263552 429 37 5 0.135135135135135 0.0116550116550117
TF TF:M03970_1 Factor: ELK1; motif: ACCGGAAGTN; match class: 1 0.0218541562163813 1097 39 8 0.205128205128205 0.0072926162260711
TF TF:M05668 Factor: ZNF154; motif: NGTGAAATCAGA 0.0218541562163813 50 82 3 0.0365853658536585 0.06
TF TF:M01273 Factor: SP4; motif: SCCCCGCCCCS 0.0218541562163813 3296 135 37 0.274074074074074 0.0112257281553398
TF TF:M00025_1 Factor: Elk-1; motif: NNNNCCGGAARTNN; match class: 1 0.0220473116526998 4639 122 44 0.360655737704918 0.00948480275921535
TF TF:M11393 Factor: Erg; motif: NACCGGATATCCGGTN 0.022676353705791 14105 118 99 0.838983050847458 0.00701878766394895
TF TF:M04934_1 Factor: TR4; motif: ACCCCGS; match class: 1 0.022676353705791 15478 141 125 0.886524822695035 0.00807597880863161
TF TF:M04107 Factor: RUNX2; motif: WRACCGCANWAACCGCAN 0.0227821020846153 12351 140 105 0.75 0.00850133592421666
TF TF:M07476 Factor: Lhx8; motif: TGATTG 0.0229585694909679 9096 73 47 0.643835616438356 0.00516710642040457
TF TF:M07356 Factor: HIF2A; motif: ACGTGNNN 0.0229888403554535 1852 140 25 0.178571428571429 0.0134989200863931
TF TF:M11434_1 Factor: Elk-1; motif: NRSCGGAAGNN; match class: 1 0.0235289853031934 2935 141 35 0.24822695035461 0.0119250425894378
TF TF:M12186 Factor: BTEB4; motif: NCCACGCCCM 0.0235769561658474 9135 138 82 0.594202898550725 0.00897646414887794
TF TF:M11882 Factor: pax-6; motif: NYACGCNYSANYGMNCN 0.0235769561658474 15490 141 125 0.886524822695035 0.00806972240154939
TF TF:M01167 Factor: SAP-1a; motif: NACCGGAAGTV 0.0235769561658474 1948 141 26 0.184397163120567 0.013347022587269
TF TF:M10578_1 Factor: Barhl-1; motif: NTAAACGN; match class: 1 0.0238399652868607 1391 4 3 0.75 0.00215672178289001
TF TF:M12086 Factor: ZNF501; motif: NNGCGACGCGAACAN 0.0239103354949514 1830 97 19 0.195876288659794 0.0103825136612022
TF TF:M11179 Factor: ASH-2; motif: ACACGACGCN 0.0239103354949514 2162 53 14 0.264150943396226 0.00647548566142461
TF TF:M11490_1 Factor: LBP-1; motif: NRCCGGTNNNNACCGGYN; match class: 1 0.0241964342953485 5988 108 48 0.444444444444444 0.00801603206412826
TF TF:M04109 Factor: RUNX3; motif: NRACCGCAAACCGCAN 0.0243373102492129 9770 141 88 0.624113475177305 0.009007164790174
TF TF:M10169 Factor: ZNF76; motif: RNNGCMTKCTGGGARNTGTAGT 0.0244429721329814 1378 118 18 0.152542372881356 0.0130624092888244
TF TF:M08304_1 Factor: FOXO1A:ETV7; motif: NWMAACAGGAMNNNCTTCCNN; match class: 1 0.0249879788341242 7620 96 52 0.541666666666667 0.0068241469816273
TF TF:M00196_1 Factor: Sp1; motif: NGGGGGCGGGGYN; match class: 1 0.0249879788341242 5919 137 58 0.423357664233577 0.00979895252576449
TF TF:M00339_1 Factor: c-Ets-1; motif: RCAGGAAGTGNNTNS; match class: 1 0.0249879788341242 1466 18 6 0.333333333333333 0.00409276944065484
TF TF:M03867_1 Factor: c-Myc; motif: CACGTGGC; match class: 1 0.0249879788341242 2694 115 28 0.243478260869565 0.0103934669636229
TF TF:M07415 Factor: Elf-1; motif: AWCCCGGAAGTN 0.0252548900560378 7978 141 75 0.531914893617021 0.00940085234394585
TF TF:M08232 Factor: Elk-1:TEF; motif: RCCGGAAGTTACGTAAN 0.0252548900560378 6188 137 60 0.437956204379562 0.0096961861667744
TF TF:M02078 Factor: SPI1; motif: NGRGGAAGTN 0.0252752426470693 3506 31 13 0.419354838709677 0.00370792926411865
TF TF:M08875_1 Factor: E2F; motif: NNTTTCGCGCN; match class: 1 0.0254048725912536 1719 96 18 0.1875 0.0104712041884817
TF TF:M01298 Factor: MECP2; motif: CCGGSNNNANNAWWT 0.0254705963189775 1290 87 14 0.160919540229885 0.0108527131782946
TF TF:M11381_1 Factor: ESE-1; motif: SATKGCGGATGCN; match class: 1 0.0256225539485866 9745 113 72 0.63716814159292 0.00738840430990251
TF TF:M09739 Factor: ZGPAT; motif: GRGGCWGNGGNG 0.0256312154424921 8226 16 13 0.8125 0.00158035497203987
TF TF:M00426_1 Factor: E2F; motif: TTTSGCGS; match class: 1 0.0256490969527965 5830 100 44 0.44 0.00754716981132075
TF TF:M04826 Factor: p300; motif: ACNTCCG 0.025734047366384 17806 141 137 0.971631205673759 0.0076940357182972
TF TF:M08457 Factor: ER71:SREBP-2; motif: NTSACGTGACGGAARY 0.025734047366384 12052 130 96 0.738461538461539 0.00796548290740126
TF TF:M08246_1 Factor: ER71:C/EBPdelta; motif: NNCGGAWRTTRCGYAAN; match class: 1 0.0257723573267203 2253 105 23 0.219047619047619 0.0102086107412339
TF TF:M11994_1 Factor: NFATc4; motif: NTTTCCRYGGAAAN; match class: 1 0.0257723573267203 36 125 3 0.024 0.0833333333333333
TF TF:M11487_1 Factor: CP2; motif: AACCGGTTNNAACCGGTT; match class: 1 0.0257723573267203 2501 84 21 0.25 0.00839664134346262
TF TF:M00050 Factor: E2F; motif: TTTSGCGC 0.026121043778453 7056 141 68 0.482269503546099 0.00963718820861678
TF TF:M03973 Factor: ELK4; motif: ACCGGAARTN 0.0261306783079143 700 141 13 0.0921985815602837 0.0185714285714286
TF TF:M01588_1 Factor: GKLF; motif: GCCMCRCCCNNN; match class: 1 0.0261535324990536 3962 135 42 0.311111111111111 0.0106007067137809
TF TF:M03791 Factor: GABPalpha_GABPbeta; motif: CTTCCKGY 0.0263298599334916 2969 141 35 0.24822695035461 0.0117884809700236
TF TF:M02063_1 Factor: c-ets-1; motif: ACCGGAWGTN; match class: 1 0.0263298599334916 2396 49 14 0.285714285714286 0.00584307178631052
TF TF:M08341 Factor: HOXB2:Elk-1; motif: TAATKRCCGGAAGTN 0.0263298599334916 6145 141 61 0.432624113475177 0.00992676973148902
TF TF:M00179_1 Factor: ATF2; motif: VGTGACGTMACN; match class: 1 0.0264629289356073 1778 140 24 0.171428571428571 0.0134983127109111
TF TF:M00933 Factor: Sp1; motif: CCCCGCCCCN 0.0264854959292627 9715 135 84 0.622222222222222 0.00864642305712815
TF TF:M07248_1 Factor: CREB1; motif: NNNNTGACGTNANNN; match class: 1 0.0265800803056992 1216 135 18 0.133333333333333 0.0148026315789474
TF TF:M11377 Factor: Spi-B; motif: NAAWGNGGAAGTN 0.0265800803056992 491 10 3 0.3 0.00610997963340122
TF TF:M01227 Factor: MafB; motif: GNTGAC 0.0266512954133905 11727 115 84 0.730434782608696 0.00716295727807623
TF TF:M11081_1 Factor: SREBP-1; motif: RTCRCGTGAY; match class: 1 0.0267776679860759 7890 7 7 1 0.000887198986058302
TF TF:M12155 Factor: Sp2; motif: NTWAGTCCCGCCCMCTT 0.0274280640328678 4591 139 48 0.345323741007194 0.0104552385101285
TF TF:M04748 Factor: GABP-alpha; motif: AACCGGAAR 0.027573754285142 16027 139 126 0.906474820143885 0.00786173332501404
TF TF:M08231_1 Factor: Elk-1:T-bet; motif: TCACACCGGAAGNN; match class: 1 0.027659055690544 1581 131 21 0.16030534351145 0.0132827324478178
TF TF:M11422 Factor: Erm; motif: NRCMGGAAGTN 0.0278931673899813 4669 39 18 0.461538461538462 0.0038552152495181
TF TF:M09869 Factor: ATF-4; motif: RNMTGATGCAAY 0.0279857588025386 2126 139 27 0.194244604316547 0.0126999059266228
TF TF:M07039_1 Factor: ETF; motif: CCCCGCCCCYN; match class: 1 0.0279857588025386 13611 138 111 0.804347826086957 0.00815516861362134
TF TF:M11996 Factor: NFATc4; motif: NTTTCCATGGAAAN 0.0281505963217198 81 125 4 0.032 0.0493827160493827
TF TF:M08870_1 Factor: DEC1; motif: NCNCACRTGNSC; match class: 1 0.0281505963217198 2440 116 26 0.224137931034483 0.010655737704918
TF TF:M04683 Factor: NF-YA; motif: YTCTSATTGGYYRN 0.0283486482838443 1657 134 22 0.164179104477612 0.0132770066385033
TF TF:M04823_1 Factor: E2F-4; motif: NNTTCCCGCCNN; match class: 1 0.0283486482838443 7850 65 38 0.584615384615385 0.00484076433121019
TF TF:M00051_1 Factor: NF-kappaB; motif: GGGGATYCCC; match class: 1 0.0284217686048188 2797 5 4 0.8 0.00143010368251698
TF TF:M11015 Factor: ISL2; motif: SCACTTAN 0.0284217686048188 4207 136 44 0.323529411764706 0.0104587592108391
TF TF:M08568_1 Factor: ER71:E2A; motif: CASSTGNACCGGAWRYN; match class: 1 0.0286249429119768 15133 127 111 0.874015748031496 0.00733496332518337
TF TF:M11541_1 Factor: Foxn2; motif: NNGCGTCNNNNNGACGCNN; match class: 1 0.0286249429119768 5493 139 55 0.39568345323741 0.0100127434917167
TF TF:M10582 Factor: Barhl2; motif: NTAATTGNY 0.0291128164530962 670 115 11 0.0956521739130435 0.0164179104477612
TF TF:M10625_1 Factor: Nkx3-2; motif: NTCGTTAN; match class: 1 0.0291128164530962 1314 69 12 0.173913043478261 0.0091324200913242
TF TF:M10580 Factor: Barhl2; motif: NTAATTGNN 0.0291128164530962 670 115 11 0.0956521739130435 0.0164179104477612
TF TF:M08453_1 Factor: ERF:SREBP-2; motif: NSCGGAARTCACGTGAT; match class: 1 0.029171816760005 3729 59 21 0.355932203389831 0.00563153660498793
TF TF:M03965 Factor: EHF; motif: NACCCGGAAGTA 0.0292761481110528 389 13 3 0.230769230769231 0.0077120822622108
TF TF:M09812_1 Factor: MYC; motif: NNCCACGTGCNN; match class: 1 0.0295561388287316 5242 7 6 0.857142857142857 0.0011446012972148
TF TF:M05544 Factor: BCL-11A; motif: CSTAMGGA 0.0297324375156555 409 63 6 0.0952380952380952 0.0146699266503667
TF TF:M03572 Factor: DEC1; motif: CNCACRTGASC 0.0297324375156555 6713 116 55 0.474137931034483 0.00819305824519589
TF TF:M04516_1 Factor: E2F-1; motif: TTTGGCGCCAAA; match class: 1 0.0297775273410979 10227 140 90 0.642857142857143 0.00880023467292461
TF TF:M01078_1 Factor: c-Ets-1; motif: NNNRCCGGAWRYNNNN; match class: 1 0.029960718860285 2448 49 14 0.285714285714286 0.00571895424836601
TF TF:M00236 Factor: Arnt; motif: NDDNNCACGTGNNNNN 0.0300451648038735 2210 6 4 0.666666666666667 0.00180995475113122
TF TF:M11217_1 Factor: CREB1; motif: NRTGACGYN; match class: 1 0.030109706975115 457 39 5 0.128205128205128 0.0109409190371991
TF TF:M11447_1 Factor: Elf-1; motif: NAMCCGGAAGTN; match class: 1 0.0303258226963374 2593 139 31 0.223021582733813 0.0119552641727729
TF TF:M04631 Factor: RREB-1; motif: GCACCCMRACY 0.0303258226963374 710 126 12 0.0952380952380952 0.0169014084507042
TF TF:M11413 Factor: ER71; motif: NACCGGAARTN 0.0306233767766448 2111 39 11 0.282051282051282 0.00521080056845097
TF TF:M06288 Factor: ZNF829; motif: NTGKACAYCAGM 0.0307979131342075 161 31 3 0.0967741935483871 0.0186335403726708
TF TF:M01154 Factor: c-Myc; motif: KACCACGTGSYY 0.0311014309223298 5313 7 6 0.857142857142857 0.00112930547713156
TF TF:M02073_1 Factor: Fli-1; motif: ACCGGAAGYN; match class: 1 0.0311933845264869 1488 39 9 0.230769230769231 0.00604838709677419
TF TF:M11066_1 Factor: HES-7; motif: GNCACGYGNN; match class: 1 0.0314598418076383 8172 7 7 1 0.000856583455702398
TF TF:M00425_1 Factor: E2F; motif: TTTCGCGC; match class: 1 0.0314598418076383 5355 140 54 0.385714285714286 0.0100840336134454
TF TF:M11271_1 Factor: JunD; motif: NRTGACGCAYN; match class: 1 0.0314598418076383 1497 113 18 0.15929203539823 0.0120240480961924
TF TF:M04065_1 Factor: Pax-6; motif: TTTCACGCWTGANTGMNYN; match class: 1 0.0316169135908138 3568 99 30 0.303030303030303 0.00840807174887892
TF TF:M09918 Factor: Pet-1; motif: GCNGGAAGYG 0.0317570879978457 13610 84 70 0.833333333333333 0.00514327700220426
TF TF:M00123 Factor: c-Myc:Max; motif: NANCACGTGNNW 0.0318318426558497 3337 7 5 0.714285714285714 0.00149835181300569
TF TF:M01967 Factor: Pbx; motif: NKTGATTGACRKSN 0.0318318426558497 5077 87 35 0.402298850574713 0.00689383494189482
TF TF:M03990_1 Factor: GABPA; motif: ACCGGAAGTN; match class: 1 0.0318318426558497 1206 39 8 0.205128205128205 0.0066334991708126
TF TF:M09866 Factor: ATF-1; motif: NNRTGACGYMA 0.0319946907595999 3162 140 36 0.257142857142857 0.0113851992409867
TF TF:M01482_1 Factor: Nkx3-2; motif: NNNAACCACTTAANNAN; match class: 1 0.0319946907595999 465 120 9 0.075 0.0193548387096774
TF TF:M09983 Factor: Max; motif: NNGCACGTGG 0.0321804307275474 116 44 3 0.0681818181818182 0.0258620689655172
TF TF:M03572_1 Factor: DEC1; motif: CNCACRTGASC; match class: 1 0.0321804307275474 1863 137 24 0.175182481751825 0.0128824476650564
TF TF:M11535_1 Factor: E2F-4; motif: TTTTGGCGCCAWWN; match class: 1 0.0321804307275474 6532 140 63 0.45 0.00964482547458665
TF TF:M01272 Factor: Sox-2; motif: NNNNCCWTTGTTWTKN 0.0321804307275474 750 90 10 0.111111111111111 0.0133333333333333
TF TF:M04691_1 Factor: Kaiso; motif: TCTCGCGAG; match class: 1 0.0321804307275474 10488 134 88 0.656716417910448 0.0083905415713196
TF TF:M11541 Factor: Foxn2; motif: NNGCGTCNNNNNGACGCNN 0.0321804307275474 5751 140 57 0.407142857142857 0.0099113197704747
TF TF:M04714_1 Factor: Elf-1; motif: ACTTCCGGG; match class: 1 0.0324215480196687 2659 131 30 0.229007633587786 0.0112824370063934
TF TF:M09892_1 Factor: E2F-1; motif: NNNNGGCGGGAARN; match class: 1 0.0329635477000326 9162 85 53 0.623529411764706 0.00578476315215019
TF TF:M08525 Factor: E2F-1:HES-7; motif: GGCRCGTGSYNNWNGGCGCSM 0.0330142655603425 17065 141 133 0.943262411347518 0.00779372985643129
TF TF:M03970 Factor: ELK1; motif: ACCGGAAGTN 0.0330952737541936 4782 39 18 0.461538461538462 0.00376411543287327
TF TF:M01258 Factor: GABP; motif: CACTTCCGGNNN 0.0330952737541936 2838 39 13 0.333333333333333 0.00458069062720226
TF TF:M08874 Factor: E2F1; motif: NNNNNGCGSSAAAN 0.0331571901763842 7201 112 56 0.5 0.00777669768087766
TF TF:M03852 Factor: SREBP-2; motif: NTCACCYNNNN 0.0331571901763842 8142 20 15 0.75 0.00184229918938836
TF TF:M04691 Factor: Kaiso; motif: TCTCGCGAG 0.0331571901763842 15113 119 104 0.873949579831933 0.00688149275458215
TF TF:M03995 Factor: SPIB; motif: NAAAAGMGGAAGTN 0.0331571901763842 759 25 5 0.2 0.00658761528326746
TF TF:M04934 Factor: TR4; motif: ACCCCGS 0.0331571901763842 18103 141 138 0.978723404255319 0.00762304590399381
TF TF:M08487 Factor: GCMa:Erg; motif: ATGCGGGCGGAARKG 0.0331571901763842 13942 132 108 0.818181818181818 0.0077463778510974
TF TF:M01203_1 Factor: SPI1; motif: NNAAWGNGGAASTNNNN; match class: 1 0.0331571901763842 211 25 3 0.12 0.014218009478673
TF TF:M08917 Factor: GABP-ALPHA; motif: RCCGGAARTNN 0.0346908908260466 2702 141 32 0.226950354609929 0.0118430792005922
TF TF:M09812 Factor: MYC; motif: NNCCACGTGCNN 0.0355183858913497 5507 7 6 0.857142857142857 0.00108952242600327
TF TF:M00431 Factor: E2F-1; motif: TTTSGCGS 0.0355580854899233 7257 100 51 0.51 0.00702769739561802
TF TF:M04694 Factor: NRF-1; motif: CNCTGCGCATGCGC 0.0355580854899233 1548 129 20 0.155038759689922 0.0129198966408269
TF TF:M09969 Factor: EKLF; motif: NGGGYGKGGCNNGG 0.0355580854899233 4589 138 47 0.340579710144928 0.0102418827631292
TF TF:M08441 Factor: AP-2gamma:Elk-1; motif: NGCCKNRGGSGRCGGAAGTG 0.0356792878894412 16345 141 129 0.914893617021277 0.00789232181095136
TF TF:M04106 Factor: RUNX2; motif: NRACCGCAAACCGCAN 0.0357698510914851 13833 137 111 0.81021897810219 0.00802428974192149
TF TF:M01165_1 Factor: Elk-1; motif: RACCGGAAGTR; match class: 1 0.0357698510914851 2185 139 27 0.194244604316547 0.0123569794050343
TF TF:M08213_1 Factor: Elk-1:TBR2; motif: TNRCACCGGAAGN; match class: 1 0.0359286930576395 1417 131 19 0.145038167938931 0.013408609738885
TF TF:M09606_1 Factor: nerf; motif: NRRNSCGGAAGNRNNNN; match class: 1 0.0361735092064893 1704 49 11 0.224489795918367 0.00645539906103286
TF TF:M00032 Factor: c-Ets-1(p54); motif: NCMGGAWGYN 0.0364626122923073 7858 141 73 0.517730496453901 0.00928989564774752
TF TF:M04419 Factor: OTX1; motif: NTAATCCN 0.0364626122923073 1693 127 21 0.165354330708661 0.0124040165386887
TF TF:M11528 Factor: E2F-2; motif: NTTTTGGCGCCAWWWN 0.0365178944902656 10373 141 91 0.645390070921986 0.00877277547479032
TF TF:M12152 Factor: Sp1; motif: NWRGCCACGCCCMCN 0.0365178944902656 7341 136 67 0.492647058823529 0.00912682195886119
TF TF:M09789 Factor: TFDP1; motif: NSGCGGGAANN 0.0365178944902656 2026 36 10 0.277777777777778 0.00493583415597236
TF TF:M04802_1 Factor: c-Fos; motif: ACTCACCA; match class: 1 0.036577198044865 1481 14 5 0.357142857142857 0.00337609723160027
TF TF:M11883_1 Factor: pax-6; motif: NYACGCNTSRNYGCNYN; match class: 1 0.0366695435178047 7768 73 41 0.561643835616438 0.00527806385169928
TF TF:M03979 Factor: ETV1; motif: ACCGGAAGTN 0.036781445693527 1024 141 16 0.113475177304965 0.015625
TF TF:M08418_1 Factor: TEF-3:Elk-1; motif: RMATWCCGGAWGT; match class: 1 0.0368866907228194 5247 141 53 0.375886524822695 0.0101010101010101
TF TF:M00991 Factor: Cdx; motif: NAYNRHNARAKTHATAAA 0.0369245727315947 3684 35 14 0.4 0.00380021715526602
TF TF:M02055 Factor: ESE-1; motif: NSMGGAARTN 0.0371651745086653 7559 39 24 0.615384615384615 0.00317502315121048
TF TF:M00426 Factor: E2F; motif: TTTSGCGS 0.0371651745086653 11885 100 74 0.74 0.0062263357172907
TF TF:M01214 Factor: ESE-1; motif: NSMGGAARTN 0.0371651745086653 7559 39 24 0.615384615384615 0.00317502315121048
TF TF:M09887 Factor: CREB1; motif: NRRTGACGTMA 0.0371651745086653 5419 140 54 0.385714285714286 0.0099649381804761
TF TF:M11448 Factor: Elf-1; motif: NANGCGGAAGTN 0.0371651745086653 7600 141 71 0.50354609929078 0.00934210526315789
TF TF:M02089_1 Factor: E2F-3; motif: GGCGGGN; match class: 1 0.0375051969819469 9362 84 53 0.630952380952381 0.00566118350779748
TF TF:M11414 Factor: GABP-alpha; motif: NACCGGAAGTN 0.0381315124325343 2907 39 13 0.333333333333333 0.00447196422428621
TF TF:M12173_1 Factor: GKLF; motif: NNCCMCRCCCN; match class: 1 0.0381942284723475 4965 53 23 0.433962264150943 0.00463242698892246
TF TF:M07034_1 Factor: ATF-1; motif: NNNTGACGTNNN; match class: 1 0.0382959300587381 1179 135 17 0.125925925925926 0.0144189991518236
TF TF:M11485 Factor: CP2; motif: AACCGGTTNNAACCGGTT 0.0388685940521978 6977 138 65 0.471014492753623 0.00931632506808084
TF TF:M09723 Factor: BTEB1; motif: GGGGGCGGGGCNGSGGGNGS 0.0391093390345255 10156 137 87 0.635036496350365 0.00856636471051595
TF TF:M01227_1 Factor: MafB; motif: GNTGAC; match class: 1 0.0391093390345255 4745 40 18 0.45 0.00379346680716544
TF TF:M11976 Factor: RFX7; motif: CGTTGCYAY 0.0392977302260002 2979 130 32 0.246153846153846 0.0107418596844579
TF TF:M02053_1 Factor: ELF1; motif: NCCGGAARTN; match class: 1 0.0396787644788363 1559 139 21 0.151079136690647 0.013470173187941
TF TF:M11439 Factor: Net; motif: NRCCGGAAGTN 0.0397608765223086 2568 39 12 0.307692307692308 0.00467289719626168
TF TF:M02066_1 Factor: PEA3; motif: RCCGGAAGYN; match class: 1 0.0399911968630711 2283 49 13 0.26530612244898 0.00569426193604906
TF TF:M08877_1 Factor: EGR3; motif: NCMCRCCCACTNMN; match class: 1 0.0400971107844487 1397 125 18 0.144 0.0128847530422334
TF TF:M10627 Factor: NKX3A; motif: NCCACTTANN 0.0406750984683044 2557 133 29 0.218045112781955 0.0113414157215487
TF TF:M01034 Factor: Ebox; motif: NCACSTGNCN 0.0408933102249677 4854 139 49 0.352517985611511 0.0100947672023074
TF TF:M09659 Factor: PU.1; motif: NRAAAGAGGAAGTGARA 0.0417140235998007 2523 6 4 0.666666666666667 0.001585414189457
TF TF:M11490 Factor: LBP-1; motif: NRCCGGTNNNNACCGGYN 0.0418774086280749 6748 93 45 0.483870967741935 0.00666864256075874
TF TF:M11451_1 Factor: Elf-1; motif: NANCCGGAAGTN; match class: 1 0.0420582780574059 2112 139 26 0.18705035971223 0.0123106060606061
TF TF:M11557 Factor: FOXE1; motif: NVYTAAAYAAACAAN 0.0420582780574059 94 128 4 0.03125 0.0425531914893617
TF TF:M02056 Factor: ELF4; motif: NCCGGAARTN 0.0420582780574059 5332 140 53 0.378571428571429 0.00993998499624906
TF TF:M11485_1 Factor: CP2; motif: AACCGGTTNNAACCGGTT; match class: 1 0.0420582780574059 6203 138 59 0.427536231884058 0.0095115266806384
TF TF:M00069_1 Factor: YY1; motif: NNNCGGCCATCTTGNCTSNW; match class: 1 0.0426093767415368 2205 107 22 0.205607476635514 0.00997732426303855
TF TF:M08205_1 Factor: E2F-1:Elk-1; motif: SGCGCSNNAMCGGAAGT; match class: 1 0.0428844114255052 10438 141 91 0.645390070921986 0.00871814523855145
TF TF:M01177_1 Factor: SREBP-2; motif: NNGYCACNNSMN; match class: 1 0.0428844114255052 2842 36 12 0.333333333333333 0.00422237860661506
TF TF:M12100 Factor: ZNF524; motif: NCTCGNACCCNN 0.0428844114255052 975 74 10 0.135135135135135 0.0102564102564103
TF TF:M10121 Factor: ZFX; motif: SNAGGCCNCR 0.0430399930648099 3997 139 42 0.302158273381295 0.010507880910683
TF TF:M11670 Factor: IRF-5; motif: NYGAAACCGAAACY 0.0430399930648099 871 139 14 0.100719424460432 0.0160734787600459
TF TF:M01783_1 Factor: SP2; motif: GGGCGGGAC; match class: 1 0.043271320374539 4333 78 28 0.358974358974359 0.00646203554119548
TF TF:M08993_1 Factor: ZNF777; motif: GTCCGYCCCGTCSAACAAT; match class: 1 0.0436202326294862 4112 17 9 0.529411764705882 0.00218871595330739
TF TF:M08800 Factor: ARNT; motif: YRCGTGNN 0.0437913615758636 914 133 14 0.105263157894737 0.0153172866520788
TF TF:M11972 Factor: rfx5; motif: NYRGCAACSGTTRCYAN 0.0437913615758636 1444 5 3 0.6 0.00207756232686981
TF TF:M03974 Factor: ERF; motif: ACCGGAAGTR 0.0439899283399387 956 141 15 0.106382978723404 0.0156903765690377
TF TF:M11399 Factor: Fli-1; motif: NACCGGAWWTCCGGTY 0.0442075435993283 12977 141 108 0.765957446808511 0.00832241658318564
TF TF:M12286 Factor: ZNF647; motif: NYAGGCCYAC 0.0445448959700693 6231 82 38 0.463414634146341 0.0060985395602632
TF TF:M11492 Factor: LBP9; motif: ACYRGTNNNNACYRGT 0.0445448959700693 7582 93 49 0.526881720430108 0.00646267475600106
TF TF:M04818_1 Factor: IRF-4; motif: RGGAASWGR; match class: 1 0.0449034849010799 3038 3 3 1 0.000987491770901909
TF TF:M04765_1 Factor: Pasx-5; motif: GTCACGSTT; match class: 1 0.0449034849010799 4135 139 43 0.309352517985612 0.0103990326481258
TF TF:M11428_1 Factor: PEA3; motif: NACCGGAAGTN; match class: 1 0.0449034849010799 2146 131 25 0.190839694656489 0.0116495806150979
TF TF:M08982 Factor: YY1; motif: NAANATGGCGNNN 0.0449034849010799 7125 96 48 0.5 0.00673684210526316
TF TF:M07601 Factor: C-Myc; motif: NGCCACGTGNN 0.0449337014163401 5882 7 6 0.857142857142857 0.00102006120367222
TF TF:M11422_1 Factor: Erm; motif: NRCMGGAAGTN; match class: 1 0.0457325248745311 934 104 12 0.115384615384615 0.012847965738758
TF TF:M11098 Factor: Max; motif: NCACGTGNNNNNCACGTGN 0.0461988276782582 826 61 8 0.131147540983607 0.00968523002421308
TF TF:M09904_1 Factor: Elk-1; motif: RCCGGAAGTGN; match class: 1 0.0464724065086608 2743 52 15 0.288461538461538 0.00546846518410499
TF TF:M11486_1 Factor: CP2; motif: AACCGGTTNNAACCGGTT; match class: 1 0.0464724065086608 2952 92 24 0.260869565217391 0.00813008130081301
TF TF:M00726_1 Factor: USF2; motif: CASGYG; match class: 1 0.0465409943171783 5942 7 6 0.857142857142857 0.0010097610232245
TF TF:M08950 Factor: MAX; motif: CACGTG 0.0465409943171783 5942 7 6 0.857142857142857 0.0010097610232245
TF TF:M08950_1 Factor: MAX; motif: CACGTG; match class: 1 0.0465409943171783 5942 7 6 0.857142857142857 0.0010097610232245
TF TF:M08458_1 Factor: Erm:C/EBPdelta; motif: RSCGGAWRTTGCGYAAY; match class: 1 0.0465409943171783 3168 110 29 0.263636363636364 0.0091540404040404
TF TF:M00280_1 Factor: RFX1; motif: NNGTNRCNWRGYAACNN; match class: 1 0.0465409943171783 1471 59 11 0.186440677966102 0.00747790618626785
TF TF:M00726 Factor: USF2; motif: CASGYG 0.0465409943171783 5942 7 6 0.857142857142857 0.0010097610232245
TF TF:M11472 Factor: PDEF; motif: NAMCCGGATGTN 0.0465409943171783 215 95 5 0.0526315789473684 0.0232558139534884
TF TF:M09611 Factor: ER81; motif: NNNGRCMGGAAGYRNNNNNNNS 0.0465409943171783 2666 141 31 0.219858156028369 0.0116279069767442
TF TF:M08284_1 Factor: Fli-1:FIGLA; motif: NCCGGAARCASSTGN; match class: 1 0.0465717196889175 2008 4 3 0.75 0.00149402390438247
TF TF:M00281_1 Factor: RFX1; motif: NNGTNRCNATRGYAACNN; match class: 1 0.0467515735253224 1010 97 12 0.123711340206186 0.0118811881188119
TF TF:M04077_1 Factor: POU3F1; motif: WTGMATAAWTNA; match class: 1 0.0467515735253224 415 50 5 0.1 0.0120481927710843
TF TF:M11486 Factor: CP2; motif: AACCGGTTNNAACCGGTT 0.0467515735253224 3658 92 28 0.304347826086957 0.00765445598687808
TF TF:M07384 Factor: HIF-1alpha; motif: NCACGTNN 0.0469137473135458 1206 6 3 0.5 0.00248756218905473
TF TF:M11215 Factor: N-Myc; motif: NNCACGTGNN 0.0469137473135458 1206 6 3 0.5 0.00248756218905473
TF TF:M08993 Factor: ZNF777; motif: GTCCGYCCCGTCSAACAAT 0.0471505491147113 10617 106 71 0.669811320754717 0.00668738815107846
TF TF:M08660_1 Factor: AP-2gamma:Dlx-3; motif: NSCCYNNRGGCANNNNYAATTA; match class: 1 0.0472786230665608 382 131 8 0.0610687022900763 0.0209424083769634
TF TF:M00122 Factor: USF; motif: NNRNCACGTGNYNN 0.0472786230665608 2413 10 5 0.5 0.00207210940737671
TF TF:M00135 Factor: Oct-1; motif: NNNNWTATGCAAATNTNNN 0.0472786230665608 2090 61 14 0.229508196721311 0.00669856459330144
TF TF:M00122_1 Factor: USF; motif: NNRNCACGTGNYNN; match class: 1 0.0472786230665608 2413 10 5 0.5 0.00207210940737671
TF TF:M10020 Factor: OSR2; motif: NNNNCWGCTNCTGNNG 0.0472786230665608 2584 45 13 0.288888888888889 0.00503095975232198
TF TF:M00119 Factor: Max; motif: NNANCACGTGNTNN 0.0473002268781432 6746 10 8 0.8 0.00118588793359028
TF TF:M00119_1 Factor: Max; motif: NNANCACGTGNTNN; match class: 1 0.0473002268781432 6746 10 8 0.8 0.00118588793359028
TF TF:M03976 Factor: ERG; motif: ACCGGAWATCCGGT 0.0473002268781432 12803 133 101 0.759398496240602 0.00788877606810904
TF TF:M08676_1 Factor: C/EBPgamma:Elf-1; motif: TKRCGHAATWSCGGAAGT; match class: 1 0.0473002268781432 2364 133 27 0.203007518796992 0.0114213197969543
TF TF:M09632 Factor: Kaiso; motif: GNTCTCGCGAGRNNNNGGN 0.0473002268781432 3001 96 25 0.260416666666667 0.00833055648117294
TF TF:M09817_1 Factor: PAX5; motif: RNGCGTGACCNN; match class: 1 0.0473002268781432 6170 65 31 0.476923076923077 0.00502431118314425
TF TF:M12183 Factor: KLF14; motif: NRCCACRCCCMCN 0.0475860157757271 6878 134 62 0.462686567164179 0.00901424832800233
TF TF:M10072_1 Factor: sp4; motif: NNGNARGRGGCGGRGCNNRR; match class: 1 0.0475965561092255 6225 136 58 0.426470588235294 0.00931726907630522
TF TF:M11393_1 Factor: Erg; motif: NACCGGATATCCGGTN; match class: 1 0.0477650944001829 13665 118 95 0.805084745762712 0.00695206732528357
TF TF:M11421 Factor: ER81; motif: NACCGGAAGTN 0.047961117371739 2341 141 28 0.198581560283688 0.0119607005553182
TF TF:M04844 Factor: Max; motif: AACACGT 0.047961117371739 1640 14 5 0.357142857142857 0.00304878048780488
TF TF:M00007 Factor: Elk-1; motif: NAAACMGGAAGTNCVH 0.0479696092298088 5873 135 55 0.407407407407407 0.00936489017537885
TF TF:M08233 Factor: ERF:C/EBPdelta; motif: NNCGGAWRTTGCGCAAY 0.048161079416044 5782 69 31 0.449275362318841 0.00536146662054652
TF TF:M08803 Factor: CREM; motif: NNTGACGT 0.048161079416044 1124 111 14 0.126126126126126 0.0124555160142349
TF TF:M00428_1 Factor: E2F-1; motif: NKTSSCGC; match class: 1 0.0488548343993866 3615 115 33 0.28695652173913 0.00912863070539419
TF TF:M00691 Factor: ATF-1; motif: CYYTGACGTCA 0.0489547651898944 4489 137 45 0.328467153284672 0.0100245043439519
TF TF:M10755 Factor: hoxd1; motif: NTCRTTAN 0.049311659320366 2948 78 21 0.269230769230769 0.00712347354138399
TF TF:M09641_1 Factor: NRF-1; motif: SYGCGCMTGCGCRNNGSN; match class: 1 0.04969483058358 991 126 14 0.111111111111111 0.0141271442986882
TF TF:M00641 Factor: HSF; motif: TTCCMGARGYTTC 0.0499344296762025 3599 45 16 0.355555555555556 0.00444567935537649
WP WP:WP3613 Photodynamic therapy-induced unfolded protein response 1.51066734625316e-10 29 100 10 0.1 0.344827586206897
WP WP:WP3888 VEGFA-VEGFR2 Signaling Pathway 0.00377583482207934 437 10 5 0.5 0.011441647597254
WP WP:WP2525 Trans-sulfuration and one carbon metabolism 0.0119157299213967 32 90 4 0.0444444444444444 0.125

pP02 transcription factor target enrichment of top program genes

TF enrichment of pP02
TFs corrosponding to activation of pP02. (Left) pearson correlation of TF expression and gene expression program activatity in Plasma cells, (right) negative log p-value for enrichment of TF binding sites among top uniqueness weighted genes for the gene program. Blue bars indicate significant TFs meeting the following criteria: FDR<0.1, overlap > 2, Corr. R > 0, permutation based p-value < 0.05.