pEpiTp12 program activity among Epithelial cells

Activation of pEpiTp12
pEpiTp12 gene program activation in Epithelial cells. (Top) Activation of program across all epithelial cells. (Bottom) Activation in MMRd (left), MMRp (middle), and normal epithelial cells (right).

Epithelial cell compositional overview

Overview of epithelial cell composition
Overview of epithelial cell composition. A tSNE plot colored by: (left) MMR status of epithelial cells, (middle) specimen, (righ) epithelial cell sub-type.
Gene program activation of pEpiTp12 by different cell subtypes
pEpiTp12 gene program activation among cells of different subtypes (Epithelial cells).

pEpiTp12 top program genes

Top genes of pEpiTp12 program
Bar plots showing the top genes for each gene program, ranked by (left) unique weights, (right) raw weights.

pEpiTp12 gene-set enrichment of top program genes (using g-profiler)

GSEA wth gene profiler of pEpiTp12
pEpiTp12 gene-set enrichment summary using g-profiler webtool.
Source termID Name Padj Tsize Qsize Overlap Precision Recall
CORUM CORUM:306 Ribosome, cytoplasmic 4.33964870161933e-52 80 30 30 1 0.375
CORUM CORUM:3055 Nop56p-associated pre-rRNA complex 8.22185685240838e-35 104 30 25 0.833333333333333 0.240384615384615
CORUM CORUM:308 60S ribosomal subunit, cytoplasmic 7.03909860716689e-25 47 21 15 0.714285714285714 0.319148936170213
CORUM CORUM:305 40S ribosomal subunit, cytoplasmic 1.93330191010587e-22 33 29 14 0.482758620689655 0.424242424242424
CORUM CORUM:338 40S ribosomal subunit, cytoplasmic 8.79657365631679e-21 31 29 13 0.448275862068966 0.419354838709677
CORUM CORUM:5380 TRBP containing complex (DICER, RPL7A, EIF6, MOV10 and subunits of the 60S ribosomal particle) 3.21882046626147e-15 25 21 9 0.428571428571429 0.36
GO:BP GO:0006614 SRP-dependent cotranslational protein targeting to membrane 2.06582099799337e-68 96 30 30 1 0.3125
GO:BP GO:0006613 cotranslational protein targeting to membrane 8.90216317620738e-68 102 30 30 1 0.294117647058824
GO:BP GO:0045047 protein targeting to ER 2.13750616405061e-66 113 30 30 1 0.265486725663717
GO:BP GO:0072599 establishment of protein localization to endoplasmic reticulum 5.33948371417547e-66 117 30 30 1 0.256410256410256
GO:BP GO:0000184 nuclear-transcribed mRNA catabolic process, nonsense-mediated decay 2.38134557614929e-65 123 30 30 1 0.24390243902439
GO:BP GO:0070972 protein localization to endoplasmic reticulum 6.54461403031354e-63 146 30 30 1 0.205479452054795
GO:BP GO:0019083 viral transcription 6.82775341723291e-60 181 30 30 1 0.165745856353591
GO:BP GO:0019080 viral gene expression 1.30927782020798e-58 199 30 30 1 0.150753768844221
GO:BP GO:0006413 translational initiation 1.60938633558422e-58 201 30 30 1 0.149253731343284
GO:BP GO:0006612 protein targeting to membrane 2.34021950942981e-58 204 30 30 1 0.147058823529412
GO:BP GO:0000956 nuclear-transcribed mRNA catabolic process 9.98176978451075e-58 214 30 30 1 0.14018691588785
GO:BP GO:0090150 establishment of protein localization to membrane 6.0346822394035e-51 351 30 30 1 0.0854700854700855
GO:BP GO:0006402 mRNA catabolic process 9.23655055252021e-50 384 30 30 1 0.078125
GO:BP GO:0006401 RNA catabolic process 1.87574521942411e-48 424 30 30 1 0.0707547169811321
GO:BP GO:0006605 protein targeting 5.93460842123003e-48 441 30 30 1 0.0680272108843537
GO:BP GO:0034655 nucleobase-containing compound catabolic process 1.31475726542488e-44 567 30 30 1 0.0529100529100529
GO:BP GO:0072594 establishment of protein localization to organelle 3.07223256176823e-44 584 30 30 1 0.0513698630136986
GO:BP GO:0046700 heterocycle catabolic process 7.38151676431097e-44 602 30 30 1 0.0498338870431894
GO:BP GO:0044270 cellular nitrogen compound catabolic process 9.48589996561828e-44 608 30 30 1 0.0493421052631579
GO:BP GO:0019439 aromatic compound catabolic process 1.90574774919153e-43 623 30 30 1 0.0481540930979133
GO:BP GO:1901361 organic cyclic compound catabolic process 7.00042378613498e-43 651 30 30 1 0.0460829493087558
GO:BP GO:0072657 protein localization to membrane 1.28362759232369e-42 665 30 30 1 0.0451127819548872
GO:BP GO:0006412 translation 8.61288444168439e-41 764 30 30 1 0.0392670157068063
GO:BP GO:0043043 peptide biosynthetic process 2.29629381067665e-40 790 30 30 1 0.0379746835443038
GO:BP GO:0016071 mRNA metabolic process 4.82360739864153e-39 874 30 30 1 0.034324942791762
GO:BP GO:0043604 amide biosynthetic process 3.2902225061229e-38 932 30 30 1 0.0321888412017167
GO:BP GO:0016032 viral process 4.38614161299039e-38 942 30 30 1 0.0318471337579618
GO:BP GO:0006518 peptide metabolic process 6.42170583602369e-38 955 30 30 1 0.031413612565445
GO:BP GO:0044403 biological process involved in symbiotic interaction 2.59782202606672e-37 1001 30 30 1 0.02997002997003
GO:BP GO:0033365 protein localization to organelle 4.06930995640062e-37 1017 30 30 1 0.0294985250737463
GO:BP GO:0006886 intracellular protein transport 4.2183994069956e-35 1186 30 30 1 0.0252951096121417
GO:BP GO:0044265 cellular macromolecule catabolic process 1.26613451353129e-34 1231 30 30 1 0.0243704305442729
GO:BP GO:0043603 cellular amide metabolic process 1.5695834843914e-34 1241 30 30 1 0.024174053182917
GO:BP GO:0010629 negative regulation of gene expression 2.10584601895351e-32 1460 30 30 1 0.0205479452054795
GO:BP GO:0009057 macromolecule catabolic process 2.41406106694283e-32 1468 30 30 1 0.0204359673024523
GO:BP GO:0046907 intracellular transport 6.42503675769726e-30 1767 30 30 1 0.0169779286926995
GO:BP GO:1901566 organonitrogen compound biosynthetic process 2.63123198349864e-29 1853 30 30 1 0.0161899622234215
GO:BP GO:0015031 protein transport 8.63655608535546e-29 1929 30 30 1 0.015552099533437
GO:BP GO:0015833 peptide transport 1.61361413414738e-28 1971 30 30 1 0.015220700152207
GO:BP GO:0042886 amide transport 2.71871200947109e-28 2007 30 30 1 0.0149476831091181
GO:BP GO:0034613 cellular protein localization 2.94667712387742e-28 2014 30 30 1 0.0148957298907646
GO:BP GO:0070727 cellular macromolecule localization 3.34092242470184e-28 2024 30 30 1 0.0148221343873518
GO:BP GO:0045184 establishment of protein localization 3.84391580285128e-28 2035 30 30 1 0.0147420147420147
GO:BP GO:0044419 biological process involved in interspecies interaction between organisms 8.34439347161842e-27 2255 30 30 1 0.0133037694013304
GO:BP GO:1901575 organic substance catabolic process 9.57704465800116e-27 2267 30 30 1 0.0132333480370534
GO:BP GO:0071705 nitrogen compound transport 1.93195953966428e-26 2322 30 30 1 0.0129198966408269
GO:BP GO:0044248 cellular catabolic process 2.61251165486953e-26 2347 30 30 1 0.0127822752449936
GO:BP GO:0009056 catabolic process 2.85615939811052e-24 2744 30 30 1 0.010932944606414
GO:BP GO:0071702 organic substance transport 3.5597639204073e-24 2766 30 30 1 0.0108459869848156
GO:BP GO:0008104 protein localization 3.64396675521094e-24 2770 30 30 1 0.0108303249097473
GO:BP GO:0051649 establishment of localization in cell 5.6849031585825e-24 2813 30 30 1 0.0106647707074298
GO:BP GO:0006820 anion transport 1.24567057947164e-23 2889 30 30 1 0.0103842159916926
GO:BP GO:0033036 macromolecule localization 3.15511105875697e-22 3218 30 30 1 0.00932256059664388
GO:BP GO:0010605 negative regulation of macromolecule metabolic process 3.83800617982476e-22 3241 30 30 1 0.00925640234495526
GO:BP GO:0009892 negative regulation of metabolic process 3.18720388920381e-21 3479 30 30 1 0.00862316757688991
GO:BP GO:0051641 cellular localization 5.32948938676624e-21 3541 30 30 1 0.00847218299915278
GO:BP GO:0006811 ion transport 1.42879922165442e-20 3661 30 30 1 0.00819448238186288
GO:BP GO:0002181 cytoplasmic translation 4.93488451049609e-19 103 30 12 0.4 0.116504854368932
GO:BP GO:0016070 RNA metabolic process 2.71754926599791e-17 4710 30 30 1 0.00636942675159236
GO:BP GO:0044271 cellular nitrogen compound biosynthetic process 1.78664551555683e-16 5017 30 30 1 0.00597966912497508
GO:BP GO:0034645 cellular macromolecule biosynthetic process 2.15333847753366e-16 5051 30 30 1 0.00593941793704217
GO:BP GO:0009059 macromolecule biosynthetic process 3.07619352535004e-16 5114 30 30 1 0.00586624951114587
GO:BP GO:0010468 regulation of gene expression 4.88542751663099e-16 5196 30 30 1 0.00577367205542725
GO:BP GO:0090304 nucleic acid metabolic process 5.63050260896545e-16 5226 30 30 1 0.00574052812858783
GO:BP GO:0006810 transport 5.63050260896545e-16 5224 30 30 1 0.0057427258805513
GO:BP GO:0044267 cellular protein metabolic process 5.64175856062164e-16 5229 30 30 1 0.0057372346528973
GO:BP GO:0051234 establishment of localization 1.25132410974119e-15 5372 30 30 1 0.00558451228592703
GO:BP GO:0006139 nucleobase-containing compound metabolic process 9.33515127226065e-15 5746 30 30 1 0.00522102332057083
GO:BP GO:0048519 negative regulation of biological process 9.74456490039689e-15 5757 30 30 1 0.00521104742053153
GO:BP GO:0019538 protein metabolic process 1.2523161622576e-14 5808 30 30 1 0.00516528925619835
GO:BP GO:0046483 heterocycle metabolic process 2.02151324673061e-14 5904 30 30 1 0.00508130081300813
GO:BP GO:0006725 cellular aromatic compound metabolic process 2.59497363221282e-14 5956 30 30 1 0.00503693754197448
GO:BP GO:0044249 cellular biosynthetic process 6.84306287185518e-14 6154 30 30 1 0.0048748781280468
GO:BP GO:0010467 gene expression 7.62583443189327e-14 6179 30 30 1 0.00485515455575336
GO:BP GO:1901360 organic cyclic compound metabolic process 8.3728387957853e-14 6201 30 30 1 0.00483792936623125
GO:BP GO:0042254 ribosome biogenesis 8.69964997305769e-14 307 28 12 0.428571428571429 0.0390879478827362
GO:BP GO:1901576 organic substance biosynthetic process 1.023415183791e-13 6248 30 30 1 0.00480153649167734
GO:BP GO:0009058 biosynthetic process 1.56796090140698e-13 6340 30 30 1 0.00473186119873817
GO:BP GO:0034641 cellular nitrogen compound metabolic process 4.3773644879571e-13 6563 30 30 1 0.00457108029864391
GO:BP GO:0060255 regulation of macromolecule metabolic process 5.18909360686105e-13 6603 30 30 1 0.00454338936846888
GO:BP GO:1901564 organonitrogen compound metabolic process 1.19725420451822e-12 6792 30 30 1 0.00441696113074205
GO:BP GO:0051179 localization 1.90866029039376e-12 6901 30 30 1 0.00434719605854224
GO:BP GO:0019222 regulation of metabolic process 5.42735852037973e-12 7148 30 30 1 0.00419697817571349
GO:BP GO:0022613 ribonucleoprotein complex biogenesis 6.63761405845188e-12 446 28 12 0.428571428571429 0.0269058295964126
GO:BP GO:0006364 rRNA processing 2.33149901935423e-10 224 28 9 0.321428571428571 0.0401785714285714
GO:BP GO:0016072 rRNA metabolic process 3.40553344984944e-10 234 28 9 0.321428571428571 0.0384615384615385
GO:BP GO:0044260 cellular macromolecule metabolic process 6.38840301489072e-10 8390 30 30 1 0.00357568533969011
GO:BP GO:0042274 ribosomal small subunit biogenesis 9.21410007695212e-09 74 28 6 0.214285714285714 0.0810810810810811
GO:BP GO:0042273 ribosomal large subunit biogenesis 1.325717404824e-08 74 14 5 0.357142857142857 0.0675675675675676
GO:BP GO:0034470 ncRNA processing 3.45834934334522e-08 397 28 9 0.321428571428571 0.0226700251889169
GO:BP GO:0043170 macromolecule metabolic process 6.42263899167702e-08 9796 30 30 1 0.00306247447937934
GO:BP GO:0042255 ribosome assembly 1.25942141610137e-07 64 24 5 0.208333333333333 0.078125
GO:BP GO:0006807 nitrogen compound metabolic process 1.47428004510995e-07 10078 30 30 1 0.00297678110736257
GO:BP GO:0034660 ncRNA metabolic process 2.15858309915406e-07 493 28 9 0.321428571428571 0.0182555780933063
GO:BP GO:0044238 primary metabolic process 6.28784091925826e-07 10584 30 30 1 0.00283446712018141
GO:BP GO:0044237 cellular metabolic process 1.39000369303814e-06 10871 30 30 1 0.00275963572808389
GO:BP GO:0071704 organic substance metabolic process 4.71440266521907e-06 11326 30 30 1 0.00264877273529931
GO:BP GO:0006396 RNA processing 5.91298672189738e-06 964 28 10 0.357142857142857 0.0103734439834025
GO:BP GO:0000027 ribosomal large subunit assembly 8.19984500216938e-06 29 14 3 0.214285714285714 0.103448275862069
GO:BP GO:0008152 metabolic process 1.67821413533746e-05 11827 30 30 1 0.00253656886784476
GO:BP GO:0022618 ribonucleoprotein complex assembly 3.14561448524778e-05 197 24 5 0.208333333333333 0.0253807106598985
GO:BP GO:0050789 regulation of biological process 3.19319381699707e-05 12091 30 30 1 0.00248118435199735
GO:BP GO:0071826 ribonucleoprotein complex subunit organization 3.65685135960961e-05 204 24 5 0.208333333333333 0.0245098039215686
GO:BP GO:0065007 biological regulation 0.000175429855433195 12809 30 30 1 0.0023421032086814
GO:BP GO:0044085 cellular component biogenesis 0.000654625045797353 3257 28 14 0.5 0.00429843414184833
GO:BP GO:0070925 organelle assembly 0.0047972610073823 895 24 6 0.25 0.00670391061452514
GO:BP GO:0043065 positive regulation of apoptotic process 0.00621185189734487 604 7 3 0.428571428571429 0.00496688741721854
GO:BP GO:0043068 positive regulation of programmed cell death 0.0066747706047825 621 7 3 0.428571428571429 0.00483091787439614
GO:BP GO:0034622 cellular protein-containing complex assembly 0.00784609722910592 1107 15 5 0.333333333333333 0.004516711833785
GO:BP GO:0010942 positive regulation of cell death 0.00853434127729307 684 7 3 0.428571428571429 0.0043859649122807
GO:BP GO:0032270 positive regulation of cellular protein metabolic process 0.03756819917227 1477 6 3 0.5 0.002031144211239
GO:BP GO:0065003 protein-containing complex assembly 0.0385878089142244 1680 15 5 0.333333333333333 0.00297619047619048
GO:BP GO:0051247 positive regulation of protein metabolic process 0.0420861948186316 1564 6 3 0.5 0.00191815856777494
GO:CC GO:0022626 cytosolic ribosome 7.86219236187934e-68 109 30 30 1 0.275229357798165
GO:CC GO:0044391 ribosomal subunit 5.00103666694873e-60 190 30 30 1 0.157894736842105
GO:CC GO:0005840 ribosome 1.20632885763488e-56 245 30 30 1 0.122448979591837
GO:CC GO:1990904 ribonucleoprotein complex 8.60296933273022e-43 688 30 30 1 0.0436046511627907
GO:CC GO:0022625 cytosolic large ribosomal subunit 2.17697352670991e-33 57 21 15 0.714285714285714 0.263157894736842
GO:CC GO:0022627 cytosolic small ribosomal subunit 5.01239045150362e-29 47 29 14 0.482758620689655 0.297872340425532
GO:CC GO:0015934 large ribosomal subunit 2.50419654823485e-28 118 21 15 0.714285714285714 0.127118644067797
GO:CC GO:0015935 small ribosomal subunit 6.04258746294431e-26 75 29 14 0.482758620689655 0.186666666666667
GO:CC GO:0005829 cytosol 2.71251246507736e-16 5303 30 30 1 0.00565717518385819
GO:CC GO:0043228 non-membrane-bounded organelle 2.82962571018975e-16 5346 30 30 1 0.00561167227833894
GO:CC GO:0043232 intracellular non-membrane-bounded organelle 2.82962571018975e-16 5338 30 30 1 0.00562008242787561
GO:CC GO:0032991 protein-containing complex 7.91510507867113e-16 5548 30 30 1 0.00540735400144196
GO:CC GO:0042788 polysomal ribosome 1.98191434458165e-15 34 30 8 0.266666666666667 0.235294117647059
GO:CC GO:0005844 polysome 9.65980568328358e-15 72 30 9 0.3 0.125
GO:CC GO:0005925 focal adhesion 4.94822323167183e-12 420 30 12 0.4 0.0285714285714286
GO:CC GO:0030055 cell-substrate junction 5.63621324799987e-12 427 30 12 0.4 0.0281030444964871
GO:CC GO:0070161 anchoring junction 1.25647288200427e-08 836 30 12 0.4 0.0143540669856459
GO:CC GO:0070062 extracellular exosome 1.53861569015621e-08 2176 30 17 0.566666666666667 0.0078125
GO:CC GO:1903561 extracellular vesicle 2.53798787547976e-08 2261 30 17 0.566666666666667 0.0075187969924812
GO:CC GO:0043230 extracellular organelle 2.53798787547976e-08 2263 30 17 0.566666666666667 0.00751215201060539
GO:CC GO:0098556 cytoplasmic side of rough endoplasmic reticulum membrane 2.23944377697099e-07 6 26 3 0.115384615384615 0.5
GO:CC GO:0005783 endoplasmic reticulum 2.24675641209273e-06 1982 26 13 0.5 0.0065590312815338
GO:CC GO:0005615 extracellular space 3.54150510325418e-06 3594 30 18 0.6 0.00500834724540901
GO:CC GO:0005737 cytoplasm 3.71550644573109e-06 11911 30 30 1 0.00251868021156914
GO:CC GO:0098554 cytoplasmic side of endoplasmic reticulum membrane 5.21944533601903e-06 16 26 3 0.115384615384615 0.1875
GO:CC GO:0043229 intracellular organelle 1.43041839339918e-05 12491 30 30 1 0.00240172924505644
GO:CC GO:0005791 rough endoplasmic reticulum 2.08490818200895e-05 86 26 4 0.153846153846154 0.0465116279069767
GO:CC GO:0030054 cell junction 2.66256635421029e-05 2105 30 13 0.433333333333333 0.00617577197149644
GO:CC GO:0030867 rough endoplasmic reticulum membrane 2.90140881864559e-05 29 26 3 0.115384615384615 0.103448275862069
GO:CC GO:0031982 vesicle 8.97089784601946e-05 4055 30 17 0.566666666666667 0.00419235511713933
GO:CC GO:0005576 extracellular region 9.58267334254612e-05 4567 30 18 0.6 0.00394131815195971
GO:CC GO:0005730 nucleolus 0.000121979661489158 955 27 8 0.296296296296296 0.00837696335078534
GO:CC GO:0031981 nuclear lumen 0.000157000855382712 4444 29 17 0.586206896551724 0.00382538253825383
GO:CC GO:0005654 nucleoplasm 0.000246861739544486 4102 29 16 0.551724137931034 0.00390053632374451
GO:CC GO:0043226 organelle 0.000332182285208879 14008 30 30 1 0.00214163335237007
GO:CC GO:0005622 intracellular anatomical structure 0.00165050670202988 14790 30 30 1 0.00202839756592292
GO:CC GO:0070013 intracellular organelle lumen 0.00184390843252924 5402 29 17 0.586206896551724 0.00314698259903739
GO:CC GO:0043233 organelle lumen 0.00254479464327645 5565 29 17 0.586206896551724 0.00305480682839173
GO:CC GO:0031974 membrane-enclosed lumen 0.00254479464327645 5565 29 17 0.586206896551724 0.00305480682839173
GO:CC GO:0012505 endomembrane system 0.00312526282573438 4640 26 14 0.538461538461538 0.00301724137931034
GO:CC GO:0014069 postsynaptic density 0.00398503659047069 334 29 4 0.137931034482759 0.0119760479041916
GO:CC GO:0032279 asymmetric synapse 0.00415228518589314 340 29 4 0.137931034482759 0.0117647058823529
GO:CC GO:0099572 postsynaptic specialization 0.0048958548541103 358 29 4 0.137931034482759 0.0111731843575419
GO:CC GO:0098984 neuron to neuron synapse 0.00518481222652176 366 29 4 0.137931034482759 0.0109289617486339
GO:CC GO:0098562 cytoplasmic side of membrane 0.00527763761601111 194 26 3 0.115384615384615 0.0154639175257732
GO:CC GO:0043227 membrane-bounded organelle 0.0106153866808678 12858 30 27 0.9 0.00209986000933271
GO:CC GO:0005634 nucleus 0.0107161368140529 7592 29 19 0.655172413793103 0.00250263435194942
GO:CC GO:0016020 membrane 0.0296220282365076 9838 30 22 0.733333333333333 0.00223622687538118
GO:CC GO:0098794 postsynapse 0.032677116282991 639 29 4 0.137931034482759 0.00625978090766823
GO:CC GO:0043231 intracellular membrane-bounded organelle 0.0430119509850211 11296 29 23 0.793103448275862 0.00203611898016997
GO:MF GO:0003735 structural constituent of ribosome 2.38369129846368e-61 171 30 30 1 0.175438596491228
GO:MF GO:0005198 structural molecule activity 2.00392638387938e-42 698 30 30 1 0.0429799426934097
GO:MF GO:0003723 RNA binding 1.46576894226283e-24 1943 30 28 0.933333333333333 0.0144107050952136
GO:MF GO:0003676 nucleic acid binding 3.58376013864021e-15 4276 30 28 0.933333333333333 0.00654817586529467
GO:MF GO:1901363 heterocyclic compound binding 8.35132903285418e-11 6228 30 28 0.933333333333333 0.00449582530507386
GO:MF GO:0097159 organic cyclic compound binding 9.8780305892156e-11 6309 30 28 0.933333333333333 0.00443810429545094
GO:MF GO:0048027 mRNA 5'-UTR binding 2.35925225649941e-09 27 27 5 0.185185185185185 0.185185185185185
GO:MF GO:0019843 rRNA binding 1.6052593286138e-05 63 29 4 0.137931034482759 0.0634920634920635
GO:MF GO:0003729 mRNA binding 0.00511018738157106 552 27 5 0.185185185185185 0.00905797101449275
HP HP:0031640 Abnormal radial artery morphology 3.86430423848818e-15 22 30 10 0.333333333333333 0.454545454545455
HP HP:0030270 Elevated red cell adenosine deaminase level 3.86430423848818e-15 22 30 10 0.333333333333333 0.454545454545455
HP HP:0020118 Radial artery aplasia 3.86430423848818e-15 22 30 10 0.333333333333333 0.454545454545455
HP HP:0005532 Macrocytic dyserythropoietic anemia 5.10677695707617e-15 23 30 10 0.333333333333333 0.434782608695652
HP HP:0012133 Erythroid hypoplasia 9.64820099004131e-15 25 30 10 0.333333333333333 0.4
HP HP:0012410 Pure red cell aplasia 9.64820099004131e-15 25 30 10 0.333333333333333 0.4
HP HP:0006758 Malignant genitourinary tract tumor 1.33838740603699e-14 26 30 10 0.333333333333333 0.384615384615385
HP HP:0040276 Adenocarcinoma of the colon 1.852393967388e-14 27 30 10 0.333333333333333 0.37037037037037
HP HP:0001227 Abnormality of the thenar eminence 3.48987282673912e-14 29 30 10 0.333333333333333 0.344827586206897
HP HP:0030272 Abnormal erythrocyte enzyme level 3.48987282673912e-14 29 30 10 0.333333333333333 0.344827586206897
HP HP:0011904 Persistence of hemoglobin F 4.34457527681105e-14 30 30 10 0.333333333333333 0.333333333333333
HP HP:0040275 Adenocarcinoma of the large intestine 4.34457527681105e-14 30 30 10 0.333333333333333 0.333333333333333
HP HP:0001895 Normochromic anemia 5.89596678909302e-14 31 30 10 0.333333333333333 0.32258064516129
HP HP:0001896 Reticulocytopenia 1.0577290508663e-13 33 30 10 0.333333333333333 0.303030303030303
HP HP:0002669 Osteosarcoma 1.0577290508663e-13 33 30 10 0.333333333333333 0.303030303030303
HP HP:0040273 Adenocarcinoma of the intestines 1.95071631810322e-13 35 30 10 0.333333333333333 0.285714285714286
HP HP:0009944 Partial duplication of thumb phalanx 3.45528420685889e-13 37 30 10 0.333333333333333 0.27027027027027
HP HP:0012131 Abnormal number of erythroid precursors 4.41073579238881e-13 38 30 10 0.333333333333333 0.263157894736842
HP HP:0009999 Partial duplication of the phalanx of hand 5.31673661387078e-13 39 30 10 0.333333333333333 0.256410256410256
HP HP:0005518 Increased mean corpuscular volume 5.31673661387078e-13 39 30 10 0.333333333333333 0.256410256410256
HP HP:0001790 Nonimmune hydrops fetalis 8.85657499165211e-13 41 30 10 0.333333333333333 0.24390243902439
HP HP:0009777 Absent thumb 1.84825255701009e-12 44 30 10 0.333333333333333 0.227272727272727
HP HP:0025065 Abnormal mean corpuscular volume 5.73659230984049e-12 49 30 10 0.333333333333333 0.204081632653061
HP HP:0001894 Thrombocytosis 6.84387766690832e-12 50 30 10 0.333333333333333 0.2
HP HP:0000912 Sprengel anomaly 8.13918895341395e-12 51 30 10 0.333333333333333 0.196078431372549
HP HP:0009942 Duplication of thumb phalanx 1.18454353813515e-11 53 30 10 0.333333333333333 0.188679245283019
HP HP:0011902 Abnormal hemoglobin 1.39419051456482e-11 54 30 10 0.333333333333333 0.185185185185185
HP HP:0001972 Macrocytic anemia 4.13261877413466e-11 60 30 10 0.333333333333333 0.166666666666667
HP HP:0001087 Developmental glaucoma 7.88597957668339e-11 64 30 10 0.333333333333333 0.15625
HP HP:0009380 Aplasia of the fingers 9.87288554498172e-11 66 30 10 0.333333333333333 0.151515151515152
HP HP:0002672 Gastrointestinal carcinoma 9.87288554498172e-11 66 30 10 0.333333333333333 0.151515151515152
HP HP:0006749 Malignant gastrointestinal tract tumors 9.87288554498172e-11 66 30 10 0.333333333333333 0.151515151515152
HP HP:0001199 Triphalangeal thumb 1.08775624005327e-10 67 30 10 0.333333333333333 0.149253731343284
HP HP:0004808 Acute myeloid leukemia 1.08775624005327e-10 67 30 10 0.333333333333333 0.149253731343284
HP HP:0004312 Abnormal reticulocyte morphology 2.23827971279025e-10 72 30 10 0.333333333333333 0.138888888888889
HP HP:0100273 Neoplasm of the colon 4.98214574291923e-10 78 30 10 0.333333333333333 0.128205128205128
HP HP:0000085 Horseshoe kidney 8.10670942532536e-10 82 30 10 0.333333333333333 0.121951219512195
HP HP:0001421 Abnormality of the musculature of the hand 1.82289776821276e-09 89 30 10 0.333333333333333 0.112359550561798
HP HP:0010622 Neoplasm of the skeletal system 2.77590770414914e-09 93 30 10 0.333333333333333 0.10752688172043
HP HP:0001789 Hydrops fetalis 3.35721416898275e-09 95 30 10 0.333333333333333 0.105263157894737
HP HP:0009778 Short thumb 4.4837955258326e-09 98 30 10 0.333333333333333 0.102040816326531
HP HP:0002863 Myelodysplasia 5.9303759121102e-09 101 30 10 0.333333333333333 0.099009900990099
HP HP:0002488 Acute leukemia 7.05408919866448e-09 103 30 10 0.333333333333333 0.0970873786407767
HP HP:0000294 Low anterior hairline 7.5956927151988e-09 104 30 10 0.333333333333333 0.0961538461538462
HP HP:0100834 Neoplasm of the large intestine 8.98912268361776e-09 106 30 10 0.333333333333333 0.0943396226415094
HP HP:0000465 Webbed neck 1.39375207781978e-08 111 30 10 0.333333333333333 0.0900900900900901
HP HP:0001680 Coarctation of aorta 1.62970769247347e-08 113 30 10 0.333333333333333 0.0884955752212389
HP HP:0000519 Developmental cataract 4.59609510193688e-08 126 30 10 0.333333333333333 0.0793650793650794
HP HP:0009601 Aplasia/Hypoplasia of the thumb 4.59609510193688e-08 126 30 10 0.333333333333333 0.0793650793650794
HP HP:0008551 Microtia 8.24654119616092e-08 134 30 10 0.333333333333333 0.0746268656716418
HP HP:0000980 Pallor 1.07802932158256e-07 138 30 10 0.333333333333333 0.072463768115942
HP HP:0008772 Aplasia/Hypoplasia of the external ear 1.13453248436888e-07 139 30 10 0.333333333333333 0.0719424460431655
HP HP:0001909 Leukemia 1.46774430049458e-07 143 30 10 0.333333333333333 0.0699300699300699
HP HP:0008771 Aplasia/Hypoplasia of the ear 1.54164048996144e-07 144 30 10 0.333333333333333 0.0694444444444444
HP HP:0000782 Abnormal scapula morphology 1.81639647523213e-07 147 30 10 0.333333333333333 0.0680272108843537
HP HP:0000599 Abnormality of the frontal hairline 1.81639647523213e-07 147 30 10 0.333333333333333 0.0680272108843537
HP HP:0000185 Cleft soft palate 4.29857856110201e-07 161 30 10 0.333333333333333 0.062111801242236
HP HP:0100542 Abnormal localization of kidney 4.67616391221726e-07 163 30 10 0.333333333333333 0.0613496932515337
HP HP:0001875 Neutropenia 4.67616391221726e-07 163 30 10 0.333333333333333 0.0613496932515337
HP HP:0010972 Anemia of inadequate production 5.08464288951511e-07 165 30 10 0.333333333333333 0.0606060606060606
HP HP:0100242 Sarcoma 5.08464288951511e-07 165 30 10 0.333333333333333 0.0606060606060606
HP HP:0000104 Renal agenesis 7.04290777032042e-07 171 30 10 0.333333333333333 0.0584795321637427
HP HP:0011991 Abnormal neutrophil count 8.1833736285904e-07 174 30 10 0.333333333333333 0.0574712643678161
HP HP:0009602 Abnormality of thumb phalanx 1.59760654194059e-06 187 30 10 0.333333333333333 0.053475935828877
HP HP:0001254 Lethargy 1.73956810224329e-06 189 30 10 0.333333333333333 0.0529100529100529
HP HP:0009774 Triangular shaped phalanges of the hand 1.98797912600189e-06 192 30 10 0.333333333333333 0.0520833333333333
HP HP:0410030 Cleft lip 2.74371111806653e-06 199 30 10 0.333333333333333 0.050251256281407
HP HP:0001446 Abnormality of the musculature of the upper limbs 3.11113930711357e-06 202 30 10 0.333333333333333 0.0495049504950495
HP HP:0100736 Abnormal soft palate morphology 3.68445954866502e-06 206 30 10 0.333333333333333 0.0485436893203883
HP HP:0009997 Duplication of phalanx of hand 3.9753349306997e-06 208 30 10 0.333333333333333 0.0480769230769231
HP HP:0009142 Duplication of bones involving the upper extremities 4.04208388795274e-06 209 30 10 0.333333333333333 0.0478468899521531
HP HP:0004275 Duplication of hand bones 4.04208388795274e-06 209 30 10 0.333333333333333 0.0478468899521531
HP HP:0009553 Abnormality of the hairline 4.7582471332319e-06 213 30 10 0.333333333333333 0.0469483568075117
HP HP:0032309 Abnormal granulocyte count 4.83797359490496e-06 214 30 10 0.333333333333333 0.0467289719626168
HP HP:0007379 Neoplasm of the genitourinary tract 4.83797359490496e-06 214 30 10 0.333333333333333 0.0467289719626168
HP HP:0001882 Leukopenia 5.67213985267579e-06 218 30 10 0.333333333333333 0.0458715596330275
HP HP:0001518 Small for gestational age 5.84167476504079e-06 219 30 10 0.333333333333333 0.045662100456621
HP HP:0009381 Short finger 8.03412980138573e-06 287 30 11 0.366666666666667 0.0383275261324042
HP HP:0002250 Abnormal large intestine morphology 1.09285703255416e-05 235 30 10 0.333333333333333 0.0425531914893617
HP HP:0004377 Hematological neoplasm 1.30958511769848e-05 240 30 10 0.333333333333333 0.0416666666666667
HP HP:0000047 Hypospadias 1.3738701568961e-05 304 30 11 0.366666666666667 0.0361842105263158
HP HP:0001874 Abnormality of neutrophils 1.78964917310396e-05 249 30 10 0.333333333333333 0.0401606425702811
HP HP:0011361 Congenital abnormal hair pattern 2.04468872969207e-05 253 30 10 0.333333333333333 0.0395256916996047
HP HP:0100037 Abnormality of the scalp hair 2.13415423032634e-05 319 30 11 0.366666666666667 0.0344827586206897
HP HP:0100627 Displacement of the urethral meatus 2.14985576698098e-05 320 30 11 0.366666666666667 0.034375
HP HP:0032076 Abnormal male urethral meatus morphology 2.14985576698098e-05 320 30 11 0.366666666666667 0.034375
HP HP:0006265 Aplasia/Hypoplasia of fingers 2.40169295072436e-05 324 30 11 0.366666666666667 0.0339506172839506
HP HP:0007378 Neoplasm of the gastrointestinal tract 2.64953582533625e-05 262 30 10 0.333333333333333 0.0381679389312977
HP HP:0001965 Abnormal scalp morphology 2.7289538968006e-05 329 30 11 0.366666666666667 0.033434650455927
HP HP:0007700 Ocular anterior segment dysgenesis 5.52739283486804e-05 285 30 10 0.333333333333333 0.0350877192982456
HP HP:0010720 Abnormal hair pattern 5.81939859044408e-05 287 30 10 0.333333333333333 0.0348432055749129
HP HP:0001911 Abnormal granulocyte morphology 6.31621638663222e-05 290 30 10 0.333333333333333 0.0344827586206897
HP HP:0001631 Atrial septal defect 6.44751298880688e-05 361 30 11 0.366666666666667 0.0304709141274238
HP HP:0011994 Abnormal atrial septum morphology 6.72833629502291e-05 363 30 11 0.366666666666667 0.0303030303030303
HP HP:0008678 Renal hypoplasia/aplasia 7.34064643761449e-05 296 30 10 0.333333333333333 0.0337837837837838
HP HP:0005922 Abnormal hand morphology 8.33965379624684e-05 372 30 11 0.366666666666667 0.0295698924731183
HP HP:0000795 Abnormality of the urethra 8.46918966932928e-05 373 30 11 0.366666666666667 0.0294906166219839
HP HP:0010974 Abnormal myeloid leukocyte morphology 0.000112353486918661 312 30 10 0.333333333333333 0.032051282051282
HP HP:0001629 Ventricular septal defect 0.000112353486918661 385 30 11 0.366666666666667 0.0285714285714286
HP HP:0010438 Abnormal ventricular septum morphology 0.000133951117941506 393 30 11 0.366666666666667 0.0279898218829517
HP HP:0001679 Abnormal aortic morphology 0.000133951117941506 319 30 10 0.333333333333333 0.0313479623824451
HP HP:0000286 Epicanthus 0.000141621422178578 476 30 12 0.4 0.0252100840336134
HP HP:0000501 Glaucoma 0.000143493230065842 323 30 10 0.333333333333333 0.0309597523219814
HP HP:0001873 Thrombocytopenia 0.000143493230065842 323 30 10 0.333333333333333 0.0309597523219814
HP HP:0011792 Neoplasm by histology 0.000143493230065842 323 30 10 0.333333333333333 0.0309597523219814
HP HP:0000470 Short neck 0.000171431716528105 330 30 10 0.333333333333333 0.0303030303030303
HP HP:0011873 Abnormal platelet count 0.00022585619722778 341 30 10 0.333333333333333 0.0293255131964809
HP HP:0001172 Abnormal thumb morphology 0.000235392510276689 343 30 10 0.333333333333333 0.0291545189504373
HP HP:0005120 Abnormal cardiac atrium morphology 0.000242945417847937 422 30 11 0.366666666666667 0.0260663507109005
HP HP:0011893 Abnormal leukocyte count 0.00030348764992424 354 30 10 0.333333333333333 0.0282485875706215
HP HP:0004372 Reduced consciousness/confusion 0.00040025833580337 366 30 10 0.333333333333333 0.0273224043715847
HP HP:0003319 Abnormality of the cervical spine 0.000425314414942932 369 30 10 0.333333333333333 0.02710027100271
HP HP:0001872 Abnormal thrombocyte morphology 0.00047275178626305 374 30 10 0.333333333333333 0.0267379679144385
HP HP:0005927 Aplasia/hypoplasia involving bones of the hand 0.00067963799723673 474 30 11 0.366666666666667 0.0232067510548523
HP HP:0000431 Wide nasal bridge 0.00103472643515449 497 30 11 0.366666666666667 0.0221327967806841
HP HP:0005280 Depressed nasal bridge 0.00110245396453941 501 30 11 0.366666666666667 0.0219560878243513
HP HP:0006496 Aplasia/hypoplasia involving bones of the upper limbs 0.00117384745594945 505 30 11 0.366666666666667 0.0217821782178218
HP HP:0011004 Abnormal systemic arterial morphology 0.00160057304095406 435 30 10 0.333333333333333 0.0229885057471264
HP HP:0012379 Abnormal enzyme/coenzyme activity 0.00194669593480002 446 30 10 0.333333333333333 0.0224215246636771
HP HP:0011927 Short digit 0.00197534698506246 537 30 11 0.366666666666667 0.0204841713221601
HP HP:0001713 Abnormal cardiac ventricle morphology 0.00202416410639113 539 30 11 0.366666666666667 0.0204081632653061
HP HP:0000464 Abnormality of the neck 0.00214229685027076 543 30 11 0.366666666666667 0.0202578268876611
HP HP:0000175 Cleft palate 0.0021945086730079 545 30 11 0.366666666666667 0.0201834862385321
HP HP:0100737 Abnormal hard palate morphology 0.00221206097140474 546 30 11 0.366666666666667 0.0201465201465201
HP HP:0009127 Abnormality of the musculature of the limbs 0.00273675326478799 468 30 10 0.333333333333333 0.0213675213675214
HP HP:0001671 Abnormal cardiac septum morphology 0.00334950366273383 574 30 11 0.366666666666667 0.0191637630662021
HP HP:0000377 Abnormality of the pinna 0.00334950366273383 673 30 12 0.4 0.0178306092124814
HP HP:0030962 Abnormal morphology of the great vessels 0.00335981043246374 575 30 11 0.366666666666667 0.0191304347826087
HP HP:0000202 Oral cleft 0.00373693754503511 583 30 11 0.366666666666667 0.0188679245283019
HP HP:0000969 Edema 0.00373693754503511 489 30 10 0.333333333333333 0.0204498977505112
HP HP:0000369 Low-set ears 0.00387461566324423 686 30 12 0.4 0.0174927113702624
HP HP:0045060 Aplasia/hypoplasia involving bones of the extremities 0.00455812826409535 598 30 11 0.366666666666667 0.0183946488294314
HP HP:0001881 Abnormal leukocyte morphology 0.00505084161068075 510 30 10 0.333333333333333 0.0196078431372549
HP HP:0010987 Abnormal cellular immune system morphology 0.00505084161068075 510 30 10 0.333333333333333 0.0196078431372549
HP HP:0000357 Abnormal location of ears 0.00591776997771576 721 30 12 0.4 0.0166435506241331
HP HP:0001903 Anemia 0.00652023723479585 528 30 10 0.333333333333333 0.0189393939393939
HP HP:0032251 Abnormal immune system morphology 0.00685474986227084 532 30 10 0.333333333333333 0.018796992481203
HP HP:0000218 High palate 0.00685474986227084 631 30 11 0.366666666666667 0.01743264659271
HP HP:0000036 Abnormal penis morphology 0.0069873530448722 633 30 11 0.366666666666667 0.0173775671406003
HP HP:0009815 Aplasia/hypoplasia of the extremities 0.00774555180880697 642 30 11 0.366666666666667 0.0171339563862928
HP HP:0011032 Abnormality of fluid regulation 0.0100722357588168 562 30 10 0.333333333333333 0.0177935943060498
HP HP:0001877 Abnormal erythrocyte morphology 0.0114262984457299 572 30 10 0.333333333333333 0.0174825174825175
HP HP:0000347 Micrognathia 0.0148206097100792 697 30 11 0.366666666666667 0.0157819225251076
HP HP:0009118 Aplasia/Hypoplasia of the mandible 0.0153023647981457 701 30 11 0.366666666666667 0.0156918687589158
HP HP:0010936 Abnormality of the lower urinary tract 0.0153023647981457 701 30 11 0.366666666666667 0.0156918687589158
HP HP:0009116 Aplasia/Hypoplasia involving bones of the skull 0.0170134230906625 711 30 11 0.366666666666667 0.0154711673699015
HP HP:0005918 Abnormal finger phalanx morphology 0.0227798655104426 631 30 10 0.333333333333333 0.0158478605388273
HP HP:0000508 Ptosis 0.0246124514886615 639 30 10 0.333333333333333 0.0156494522691706
HP HP:0000316 Hypertelorism 0.0317963974879481 663 30 10 0.333333333333333 0.0150829562594268
HP HP:0009122 Aplasia/hypoplasia affecting bones of the axial skeleton 0.0397487929150381 797 30 11 0.366666666666667 0.013801756587202
HP HP:0033353 Abnormal blood vessel morphology 0.0402377625840144 799 30 11 0.366666666666667 0.0137672090112641
HP HP:0000518 Cataract 0.0403999483686747 688 30 10 0.333333333333333 0.0145348837209302
HP HP:0011793 Neoplasm by anatomical site 0.0404687383286522 801 30 11 0.366666666666667 0.0137328339575531
HP HP:0025015 Abnormal vascular morphology 0.0405861645134372 802 30 11 0.366666666666667 0.013715710723192
HP HP:0000422 Abnormal nasal bridge morphology 0.0426686019350276 925 30 12 0.4 0.012972972972973
HP HP:0000517 Abnormality of the lens 0.046911744440827 707 30 10 0.333333333333333 0.0141442715700141
HPA HPA:0350473 pancreas; exocrine glandular cells[High] 0.000480293203074516 1879 30 17 0.566666666666667 0.00904736562001064
HPA HPA:0190223 esophagus; squamous epithelial cells[High] 0.000975649541382019 1596 30 15 0.5 0.0093984962406015
HPA HPA:0050053 breast; glandular cells[High] 0.0107175199461752 1299 30 12 0.4 0.0092378752886836
HPA HPA:0110223 cervix, uterine; squamous epithelial cells[High] 0.0136974394704174 986 30 10 0.333333333333333 0.0101419878296146
HPA HPA:0250133 hippocampus; neuronal cells[High] 0.0136974394704174 1210 30 11 0.366666666666667 0.00909090909090909
HPA HPA:0330223 oral mucosa; squamous epithelial cells[High] 0.0136974394704174 1112 7 5 0.714285714285714 0.00449640287769784
HPA HPA:0090162 cerebellum; Purkinje cells[≥Medium] 0.0150076571929513 4047 30 21 0.7 0.00518902891030393
HPA HPA:0250132 hippocampus; neuronal cells[≥Medium] 0.0159082954873003 4126 30 21 0.7 0.00508967523024721
HPA HPA:0080133 caudate; neuronal cells[High] 0.0159082954873003 1059 30 10 0.333333333333333 0.00944287063267233
HPA HPA:0100133 cerebral cortex; neuronal cells[High] 0.0166448309198795 1785 30 13 0.433333333333333 0.00728291316526611
HPA HPA:0530722 spleen; cells in white pulp[≥Medium] 0.019537228955675 2645 30 16 0.533333333333333 0.00604914933837429
HPA HPA:0420053 salivary gland; glandular cells[High] 0.019537228955675 1418 29 11 0.379310344827586 0.0077574047954866
HPA HPA:0600223 tonsil; squamous epithelial cells[High] 0.0268849180726053 1442 30 11 0.366666666666667 0.00762829403606103
HPA HPA:0420052 salivary gland; glandular cells[≥Medium] 0.0268849180726053 4742 30 22 0.733333333333333 0.00463939266132434
HPA HPA:0090163 cerebellum; Purkinje cells[High] 0.0404804454382404 1527 30 11 0.366666666666667 0.00720366732154551
HPA HPA:0380511 placenta; decidual cells[≥Low] 0.0408825975859794 4716 19 15 0.789473684210526 0.00318066157760814
HPA HPA:0060103 bronchus; respiratory epithelial cells[High] 0.0437241443668341 1890 29 12 0.413793103448276 0.00634920634920635
HPA HPA:0470683 skin 2; epidermal cells[High] 0.0467420650099479 1346 30 10 0.333333333333333 0.00742942050520059
HPA HPA:0110222 cervix, uterine; squamous epithelial cells[≥Medium] 0.0468496680463612 3617 30 18 0.6 0.00497649986176389
KEGG KEGG:03010 Ribosome 2.38628829080991e-52 153 30 30 1 0.196078431372549
KEGG KEGG:05171 Coronavirus disease - COVID-19 8.1666065204267e-47 231 30 30 1 0.12987012987013
MIRNA MIRNA:hsa-miR-652-3p hsa-miR-652-3p 2.46352838822633e-07 162 28 8 0.285714285714286 0.0493827160493827
MIRNA MIRNA:hsa-miR-100-5p hsa-miR-100-5p 6.93409967737411e-06 250 30 8 0.266666666666667 0.032
MIRNA MIRNA:hsa-miR-766-3p hsa-miR-766-3p 0.0209139334938065 604 21 6 0.285714285714286 0.00993377483443709
MIRNA MIRNA:hsa-miR-1260b hsa-miR-1260b 0.033563940946475 270 27 4 0.148148148148148 0.0148148148148148
MIRNA MIRNA:hsa-miR-99a-5p hsa-miR-99a-5p 0.033563940946475 131 20 3 0.15 0.0229007633587786
MIRNA MIRNA:hsa-miR-92a-3p hsa-miR-92a-3p 0.033563940946475 1404 25 8 0.32 0.0056980056980057
MIRNA MIRNA:hsa-miR-877-5p hsa-miR-877-5p 0.033563940946475 233 24 4 0.166666666666667 0.0171673819742489
MIRNA MIRNA:hsa-let-7a-5p hsa-let-7a-5p 0.033563940946475 637 25 5 0.2 0.00784929356357928
MIRNA MIRNA:hsa-miR-125b-5p hsa-miR-125b-5p 0.033563940946475 427 27 5 0.185185185185185 0.0117096018735363
MIRNA MIRNA:hsa-miR-423-5p hsa-miR-423-5p 0.033563940946475 342 14 3 0.214285714285714 0.0087719298245614
MIRNA MIRNA:hsa-miR-324-3p hsa-miR-324-3p 0.033563940946475 336 14 3 0.214285714285714 0.00892857142857143
MIRNA MIRNA:hsa-miR-320a hsa-miR-320a 0.033563940946475 584 28 5 0.178571428571429 0.00856164383561644
MIRNA MIRNA:hsa-miR-31-5p hsa-miR-31-5p 0.033563940946475 223 27 4 0.148148148148148 0.0179372197309417
MIRNA MIRNA:hsa-miR-30c-5p hsa-miR-30c-5p 0.033563940946475 519 8 3 0.375 0.00578034682080925
MIRNA MIRNA:hsa-miR-331-3p hsa-miR-331-3p 0.033563940946475 403 24 4 0.166666666666667 0.00992555831265509
MIRNA MIRNA:hsa-miR-16-5p hsa-miR-16-5p 0.033563940946475 1556 25 9 0.36 0.0057840616966581
MIRNA MIRNA:hsa-miR-484 hsa-miR-484 0.0391470057463953 890 29 6 0.206896551724138 0.00674157303370787
MIRNA MIRNA:hsa-miR-744-5p hsa-miR-744-5p 0.0414313727723521 435 14 3 0.214285714285714 0.00689655172413793
MIRNA MIRNA:hsa-miR-1277-5p hsa-miR-1277-5p 0.0473294974978616 621 11 3 0.272727272727273 0.00483091787439614
REAC REAC:R-HSA-156902 Peptide chain elongation 7.52207049606602e-63 90 30 30 1 0.333333333333333
REAC REAC:R-HSA-192823 Viral mRNA Translation 7.52207049606602e-63 90 30 30 1 0.333333333333333
REAC REAC:R-HSA-156842 Eukaryotic Translation Elongation 1.44409367050842e-62 94 30 30 1 0.319148936170213
REAC REAC:R-HSA-2408557 Selenocysteine synthesis 1.44409367050842e-62 94 30 30 1 0.319148936170213
REAC REAC:R-HSA-72764 Eukaryotic Translation Termination 1.44409367050842e-62 94 30 30 1 0.319148936170213
REAC REAC:R-HSA-975956 Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC) 2.5583011412271e-62 96 30 30 1 0.3125
REAC REAC:R-HSA-72689 Formation of a pool of free 40S subunits 1.65365834468737e-61 102 30 30 1 0.294117647058824
REAC REAC:R-HSA-9633012 Response of EIF2AK4 (GCN2) to amino acid deficiency 1.65365834468737e-61 102 30 30 1 0.294117647058824
REAC REAC:R-HSA-156827 L13a-mediated translational silencing of Ceruloplasmin expression 3.88862440464678e-60 112 30 30 1 0.267857142857143
REAC REAC:R-HSA-1799339 SRP-dependent cotranslational protein targeting to membrane 4.33157833463967e-60 113 30 30 1 0.265486725663717
REAC REAC:R-HSA-72706 GTP hydrolysis and joining of the 60S ribosomal subunit 4.33157833463967e-60 113 30 30 1 0.265486725663717
REAC REAC:R-HSA-975957 Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC) 9.07735924871517e-60 116 30 30 1 0.258620689655172
REAC REAC:R-HSA-927802 Nonsense-Mediated Decay (NMD) 9.07735924871517e-60 116 30 30 1 0.258620689655172
REAC REAC:R-HSA-2408522 Selenoamino acid metabolism 1.13355200470405e-59 117 30 30 1 0.256410256410256
REAC REAC:R-HSA-72737 Cap-dependent Translation Initiation 2.3710708365335e-59 120 30 30 1 0.25
REAC REAC:R-HSA-72613 Eukaryotic Translation Initiation 2.3710708365335e-59 120 30 30 1 0.25
REAC REAC:R-HSA-168273 Influenza Viral RNA Transcription and Replication 7.44363607419127e-58 133 30 30 1 0.225563909774436
REAC REAC:R-HSA-168255 Influenza Infection 6.21596910386927e-56 152 30 30 1 0.197368421052632
REAC REAC:R-HSA-9711097 Cellular response to starvation 1.72657232831902e-55 157 30 30 1 0.191082802547771
REAC REAC:R-HSA-9010553 Regulation of expression of SLITs and ROBOs 2.75439018742659e-54 171 30 30 1 0.175438596491228
REAC REAC:R-HSA-6791226 Major pathway of rRNA processing in the nucleolus and cytosol 2.4218891410506e-53 183 30 30 1 0.163934426229508
REAC REAC:R-HSA-8868773 rRNA processing in the nucleus and cytosol 1.30912397565845e-52 193 30 30 1 0.155440414507772
REAC REAC:R-HSA-72312 rRNA processing 6.44849055186537e-52 203 30 30 1 0.147783251231527
REAC REAC:R-HSA-376176 Signaling by ROBO receptors 5.3238386636734e-51 217 30 30 1 0.138248847926267
REAC REAC:R-HSA-72766 Translation 6.59497075299424e-47 292 30 30 1 0.102739726027397
REAC REAC:R-HSA-71291 Metabolism of amino acids and derivatives 9.08673907605245e-44 368 30 30 1 0.0815217391304348
REAC REAC:R-HSA-2262752 Cellular responses to stress 1.80972558804049e-38 546 30 30 1 0.0549450549450549
REAC REAC:R-HSA-422475 Axon guidance 2.06619367807441e-38 549 30 30 1 0.0546448087431694
REAC REAC:R-HSA-8953897 Cellular responses to external stimuli 3.67629755106172e-38 560 30 30 1 0.0535714285714286
REAC REAC:R-HSA-9675108 Nervous system development 7.60201220283035e-38 574 30 30 1 0.0522648083623693
REAC REAC:R-HSA-8953854 Metabolism of RNA 4.89240647033971e-36 658 30 30 1 0.0455927051671733
REAC REAC:R-HSA-5663205 Infectious disease 3.31539192899877e-33 815 30 30 1 0.0368098159509202
REAC REAC:R-HSA-1266738 Developmental Biology 1.25328867385318e-29 1069 30 30 1 0.0280636108512629
REAC REAC:R-HSA-1643685 Disease 4.25389343912795e-25 1509 30 30 1 0.0198807157057654
REAC REAC:R-HSA-72695 Formation of the ternary complex, and subsequently, the 43S complex 6.17372084555911e-25 52 29 14 0.482758620689655 0.269230769230769
REAC REAC:R-HSA-72702 Ribosomal scanning and start codon recognition 4.34949016497647e-24 59 29 14 0.482758620689655 0.23728813559322
REAC REAC:R-HSA-72649 Translation initiation complex formation 4.34949016497647e-24 59 29 14 0.482758620689655 0.23728813559322
REAC REAC:R-HSA-72662 Activation of the mRNA upon binding of the cap-binding complex and eIFs, and subsequent binding to 43S 5.5165795038394e-24 60 29 14 0.482758620689655 0.233333333333333
REAC REAC:R-HSA-392499 Metabolism of proteins 1.0281234808541e-21 1961 30 30 1 0.0152983171851096
REAC REAC:R-HSA-1430728 Metabolism 5.13990846409761e-21 2070 30 30 1 0.0144927536231884
TF TF:M09608 Factor: Erg; motif: NNACCGGAARTSN 1.3252571699371e-05 8152 30 28 0.933333333333333 0.00343473994111874
TF TF:M02062 Factor: Erg; motif: ACCGGAAGTN 6.72542719090648e-05 8056 30 27 0.9 0.00335153922542205
TF TF:M03988 Factor: FLI1; motif: ACCGGAARTN 9.99437201736803e-05 8318 30 27 0.9 0.0032459725895648
TF TF:M00025_1 Factor: Elk-1; motif: NNNNCCGGAARTNN; match class: 1 0.00010762000825075 4639 30 21 0.7 0.0045268376805346
TF TF:M11422 Factor: Erm; motif: NRCMGGAAGTN 0.000127392240668474 4669 22 17 0.772727272727273 0.00364103662454487
TF TF:M11392 Factor: Erg; motif: NACCGGAARYN 0.000127392240668474 8690 30 27 0.9 0.00310701956271577
TF TF:M02056_1 Factor: ELF4; motif: NCCGGAARTN; match class: 1 0.000127392240668474 1291 30 12 0.4 0.00929512006196747
TF TF:M11404 Factor: Fli-1; motif: NACCGGAARTN 0.000129625805888728 8743 30 27 0.9 0.00308818483358115
TF TF:M11396_1 Factor: Erg; motif: NACCGGAARTN; match class: 1 0.000164969768328296 4963 30 21 0.7 0.00423131170662906
TF TF:M02065_1 Factor: ER81; motif: RCCGGAARYN; match class: 1 0.000170749701472717 6749 30 24 0.8 0.0035560823825752
TF TF:M11400 Factor: Fli-1; motif: NACCGGAARTN 0.000213055074294008 9946 30 28 0.933333333333333 0.00281520209129298
TF TF:M02064 Factor: c-ets-2; motif: ACCGGAWRTN 0.000213055074294008 10939 30 29 0.966666666666667 0.00265106499680044
TF TF:M02063 Factor: c-ets-1; motif: ACCGGAWGTN 0.000221911499283114 7600 30 25 0.833333333333333 0.00328947368421053
TF TF:M02061 Factor: ERF; motif: ACCGGAARYN 0.000221911499283114 2579 7 7 1 0.00271423032183017
TF TF:M03970 Factor: ELK1; motif: ACCGGAAGTN 0.000241198490349979 4782 21 16 0.761904761904762 0.00334588038477624
TF TF:M02068 Factor: etv3; motif: ACCGGAAGYN 0.000241198490349979 3443 21 14 0.666666666666667 0.00406622131861748
TF TF:M00025 Factor: Elk-1; motif: NNNNCCGGAARTNN 0.000306950190880055 10262 21 21 1 0.00204638472032742
TF TF:M08377_1 Factor: meis1:Elf-1; motif: NTGCCGGAAGTN; match class: 1 0.000313428031480307 5051 29 20 0.689655172413793 0.00395961195802811
TF TF:M08224 Factor: Elk-1:Pax-1; motif: ACCGGAACTACGCWTSANTG 0.000349683950662809 8925 17 17 1 0.0019047619047619
TF TF:M10849 Factor: Cdx-2; motif: NRTCGTAANNNN 0.000351078325457052 11163 29 28 0.96551724137931 0.00250828630296515
TF TF:M08982_1 Factor: YY1; motif: NAANATGGCGNNN; match class: 1 0.000351078325457052 1662 29 12 0.413793103448276 0.0072202166064982
TF TF:M01165 Factor: Elk-1; motif: RACCGGAAGTR 0.000351078325457052 7773 21 19 0.904761904761905 0.00244435867747331
TF TF:M01752 Factor: ERG; motif: ACCGGAART 0.000351078325457052 9474 30 27 0.9 0.00284990500316656
TF TF:M12238_1 Factor: DREF; motif: MTRTCGCGAYAK; match class: 1 0.000370696094181053 293 15 5 0.333333333333333 0.0170648464163823
TF TF:M03982 Factor: ETV4; motif: ACCGGAAGTN 0.000375582153993162 6826 21 18 0.857142857142857 0.0026369762672136
TF TF:M08910 Factor: C/EBPBETA; motif: KRTTGCGYAAY 0.000375582153993162 4674 29 19 0.655172413793103 0.0040650406504065
TF TF:M11396 Factor: Erg; motif: NACCGGAARTN 0.000525249483808324 10765 21 21 1 0.00195076637250348
TF TF:M11382_1 Factor: ESE-1; motif: NWTRCGGAWGCN; match class: 1 0.000525249483808324 4112 20 14 0.7 0.00340466926070039
TF TF:M11392_1 Factor: Erg; motif: NACCGGAARYN; match class: 1 0.000618499581680594 3233 30 16 0.533333333333333 0.00494896381070213
TF TF:M02059 Factor: ELK-1; motif: ACCGGAAGTN 0.000650893390548355 9423 21 20 0.952380952380952 0.00212246630584739
TF TF:M08913 Factor: FLI-1; motif: NAYTTCCGGT 0.000650893390548355 8322 30 25 0.833333333333333 0.00300408555635664
TF TF:M01752_1 Factor: ERG; motif: ACCGGAART; match class: 1 0.000650893390548355 3705 30 17 0.566666666666667 0.00458839406207827
TF TF:M12238 Factor: DREF; motif: MTRTCGCGAYAK 0.000650893390548355 350 15 5 0.333333333333333 0.0142857142857143
TF TF:M11400_1 Factor: Fli-1; motif: NACCGGAARTN; match class: 1 0.000659236099960976 4201 30 18 0.6 0.00428469412044751
TF TF:M02070 Factor: TEL1; motif: CNCGGAANNN 0.000678064635775783 10837 30 28 0.933333333333333 0.00258374088769955
TF TF:M02066 Factor: PEA3; motif: RCCGGAAGYN 0.000747068200552072 7045 30 23 0.766666666666667 0.00326472675656494
TF TF:M03975 Factor: ERG; motif: ACCGGAARTN 0.000757999517690538 10002 30 27 0.9 0.0026994601079784
TF TF:M08910_1 Factor: C/EBPBETA; motif: KRTTGCGYAAY; match class: 1 0.000783009225092618 3194 25 14 0.56 0.00438321853475266
TF TF:M02056 Factor: ELF4; motif: NCCGGAARTN 0.000814049756381364 5332 30 20 0.666666666666667 0.00375093773443361
TF TF:M07140 Factor: Kaiso; motif: NTCTCGCGAGANYTN 0.000837686736063135 552 27 7 0.259259259259259 0.0126811594202899
TF TF:M08423 Factor: TEF-3:ER81; motif: ACCGGAAATRCC 0.000837686736063135 3845 30 17 0.566666666666667 0.00442132639791938
TF TF:M02071 Factor: ETV7; motif: NCCGGAANNN 0.000877939072961 10116 30 27 0.9 0.00266903914590747
TF TF:M08917 Factor: GABP-ALPHA; motif: RCCGGAARTNN 0.000908825629073965 2702 19 11 0.578947368421053 0.00407105847520355
TF TF:M01660_1 Factor: GABP-alpha; motif: CTTCCK; match class: 1 0.000991113688850548 5133 29 19 0.655172413793103 0.00370153906097799
TF TF:M02053_1 Factor: ELF1; motif: NCCGGAARTN; match class: 1 0.00101875720988413 1559 30 11 0.366666666666667 0.00705580500320718
TF TF:M08760 Factor: ETV7; motif: NNSCGGAAGTR 0.00101875720988413 2349 29 13 0.448275862068966 0.00553426990208599
TF TF:M09935 Factor: GABP-alpha; motif: NNNRCCGGAAGTGN 0.00101875720988413 4420 30 18 0.6 0.00407239819004525
TF TF:M11436 Factor: SAP-1; motif: NRNCGGAWRYN 0.00110018565376604 1431 6 5 0.833333333333333 0.00349406009783368
TF TF:M11432 Factor: Elk-1; motif: NACMGGAAGTN 0.00110018565376604 6140 22 17 0.772727272727273 0.00276872964169381
TF TF:M03924_1 Factor: YY1; motif: NNCGCCATTNN; match class: 1 0.00121884833461442 3700 29 16 0.551724137931034 0.00432432432432432
TF TF:M04287 Factor: BARHL2; motif: NNTAAAYGNN 0.00123631581365564 4416 12 10 0.833333333333333 0.00226449275362319
TF TF:M08377 Factor: meis1:Elf-1; motif: NTGCCGGAAGTN 0.00126253715048163 11275 30 28 0.933333333333333 0.00248337028824834
TF TF:M11433 Factor: Elk-1; motif: NRCCGGAAGTN 0.00126823119589162 7679 21 18 0.857142857142857 0.00234405521552285
TF TF:M08224_1 Factor: Elk-1:Pax-1; motif: ACCGGAACTACGCWTSANTG; match class: 1 0.00143325432194982 2748 30 14 0.466666666666667 0.00509461426491994
TF TF:M02067 Factor: ER71; motif: ACCGGAARYN 0.00148988191165253 5930 21 16 0.761904761904762 0.00269814502529511
TF TF:M12350 Factor: zbtb2; motif: NTTTCCGGTAAN 0.00149947588528893 418 27 6 0.222222222222222 0.0143540669856459
TF TF:M03983 Factor: ETV5; motif: NCCGGAWGYN 0.00149947588528893 3129 21 12 0.571428571428571 0.00383509108341323
TF TF:M02074 Factor: GABPalpha; motif: RCCGGAWRYN 0.00152128298682351 4607 30 18 0.6 0.00390709789450836
TF TF:M09608_1 Factor: Erg; motif: NNACCGGAARTSN; match class: 1 0.00153332442958202 2389 30 13 0.433333333333333 0.0054416073670992
TF TF:M03977 Factor: ETS1; motif: ACCGGAARYN 0.00154441978083 10512 30 27 0.9 0.00256849315068493
TF TF:M11452 Factor: Elf-1; motif: NANGCGGAAGTR 0.00155810717059368 6276 30 21 0.7 0.00334608030592734
TF TF:M01163 Factor: Elk-1; motif: AACCGGAAGTR 0.00163447065453673 5260 23 16 0.695652173913043 0.00304182509505703
TF TF:M11427 Factor: PEA3; motif: NACCGGAAGTN 0.00173490288336934 10585 30 27 0.9 0.00255077940481814
TF TF:M03985 Factor: ETV6; motif: NSCGGAAGTR 0.0017731353913517 1136 29 9 0.310344827586207 0.00792253521126761
TF TF:M08759 Factor: c-Ets-2; motif: NCCGGAAGTG 0.00194642019388704 8319 30 24 0.8 0.00288496213487198
TF TF:M09607 Factor: SAP-1; motif: ACCGGAAGTNN 0.00194642019388704 4727 30 18 0.6 0.00380791199492278
TF TF:M02044 Factor: YY1; motif: GCCGCCATTTTG 0.00200052212505458 6102 29 20 0.689655172413793 0.00327761389708292
TF TF:M11446 Factor: Elf-1; motif: RANSMGGAAGTR 0.00225500378804781 2915 30 14 0.466666666666667 0.00480274442538594
TF TF:M11438 Factor: SAP-1; motif: NTCGTAAATGCN 0.00241645773555177 5901 30 20 0.666666666666667 0.0033892560582952
TF TF:M03988_1 Factor: FLI1; motif: ACCGGAARTN; match class: 1 0.0025125009329696 2950 30 14 0.466666666666667 0.00474576271186441
TF TF:M11435 Factor: Elk-1; motif: NNCCGGAAGTN 0.00252058288346564 11728 30 28 0.933333333333333 0.00238744884038199
TF TF:M02070_1 Factor: TEL1; motif: CNCGGAANNN; match class: 1 0.00252058288346564 4841 30 18 0.6 0.00371824003305102
TF TF:M11428 Factor: PEA3; motif: NACCGGAAGTN 0.00253504785778773 7186 21 17 0.80952380952381 0.00236571110492625
TF TF:M04714 Factor: Elf-1; motif: ACTTCCGGG 0.00253504785778773 7798 30 23 0.766666666666667 0.00294947422416004
TF TF:M11402 Factor: Fli-1; motif: NACCGGAARTN 0.00267332123799594 3885 30 16 0.533333333333333 0.00411840411840412
TF TF:M11430 Factor: PEA3; motif: NACCGGAAGTN 0.00267332123799594 10865 30 27 0.9 0.00248504371836171
TF TF:M08345_1 Factor: HOXB2:PEA3; motif: ACCGGAAATGRN; match class: 1 0.00278341878502277 2198 30 12 0.4 0.00545950864422202
TF TF:M11382 Factor: ESE-1; motif: NWTRCGGAWGCN 0.00282359533959892 10339 24 22 0.916666666666667 0.00212786536415514
TF TF:M02052 Factor: EHF; motif: CSCGGAARTN 0.00308026135218274 10107 30 26 0.866666666666667 0.00257247452260809
TF TF:M03981 Factor: ETV3; motif: ACCGGAAGTN 0.00311066438931277 2327 21 10 0.476190476190476 0.00429737859905458
TF TF:M11448_1 Factor: Elf-1; motif: NANGCGGAAGTN; match class: 1 0.00311066438931277 2324 29 12 0.413793103448276 0.00516351118760757
TF TF:M08913_1 Factor: FLI-1; motif: NAYTTCCGGT; match class: 1 0.00315906930622385 3055 30 14 0.466666666666667 0.00458265139116203
TF TF:M10436 Factor: YY1; motif: CAANATGGCGGC 0.00315906930622385 8220 26 21 0.807692307692308 0.00255474452554745
TF TF:M00179 Factor: ATF2; motif: VGTGACGTMACN 0.00343491838599685 6065 26 18 0.692307692307692 0.00296784830997527
TF TF:M03975_1 Factor: ERG; motif: ACCGGAARTN; match class: 1 0.0037513033030992 4024 30 16 0.533333333333333 0.00397614314115308
TF TF:M11394 Factor: Erg; motif: NACMGGAARTN 0.00403736468010349 4051 30 16 0.533333333333333 0.00394964206368798
TF TF:M02065 Factor: ER81; motif: RCCGGAARYN 0.00412349832740386 12550 21 21 1 0.00167330677290837
TF TF:M11425 Factor: PEA3; motif: NACCGGAAGTN 0.00420558474098875 7428 30 22 0.733333333333333 0.00296176628971459
TF TF:M02062_1 Factor: Erg; motif: ACCGGAAGTN; match class: 1 0.00434629903019035 2718 16 9 0.5625 0.0033112582781457
TF TF:M11404_1 Factor: Fli-1; motif: NACCGGAARTN; match class: 1 0.00442626083153835 3171 30 14 0.466666666666667 0.00441501103752759
TF TF:M00916 Factor: CREB; motif: NNTKACGTCANNNS 0.00442626083153835 5889 27 18 0.666666666666667 0.00305654610290372
TF TF:M02074_1 Factor: GABPalpha; motif: RCCGGAWRYN; match class: 1 0.0045967052029999 1005 16 6 0.375 0.00597014925373134
TF TF:M04698 Factor: GABP-alpha; motif: CACTTCCGG 0.0045967052029999 3196 30 14 0.466666666666667 0.00438047559449312
TF TF:M11316 Factor: C/EBPbeta; motif: NRTTGCGYAAYN 0.0045967052029999 5225 25 16 0.64 0.0030622009569378
TF TF:M09904 Factor: Elk-1; motif: RCCGGAAGTGN 0.0045967052029999 8164 30 23 0.766666666666667 0.0028172464478197
TF TF:M02073 Factor: Fli-1; motif: ACCGGAAGYN 0.0045967052029999 5839 19 14 0.736842105263158 0.00239767083404693
TF TF:M11451 Factor: Elf-1; motif: NANCCGGAAGTN 0.00468998317094256 6886 30 21 0.7 0.00304966598896311
TF TF:M02063_1 Factor: c-ets-1; motif: ACCGGAWGTN; match class: 1 0.0049323379825462 2396 30 12 0.4 0.00500834724540901
TF TF:M01214 Factor: ESE-1; motif: NSMGGAARTN 0.0049323379825462 7559 30 22 0.733333333333333 0.0029104378886096
TF TF:M11435_1 Factor: Elk-1; motif: NNCCGGAAGTN; match class: 1 0.0049323379825462 5745 30 19 0.633333333333333 0.00330722367275892
TF TF:M02055 Factor: ESE-1; motif: NSMGGAARTN 0.0049323379825462 7559 30 22 0.733333333333333 0.0029104378886096
TF TF:M03977_1 Factor: ETS1; motif: ACCGGAARYN; match class: 1 0.0049323379825462 4677 30 17 0.566666666666667 0.00363480863801582
TF TF:M01078 Factor: c-Ets-1; motif: NNNRCCGGAWRYNNNN 0.0049323379825462 7544 30 22 0.733333333333333 0.00291622481442206
TF TF:M11434_1 Factor: Elk-1; motif: NRSCGGAAGNN; match class: 1 0.00509374537366194 2935 29 13 0.448275862068966 0.00442930153321976
TF TF:M04691_1 Factor: Kaiso; motif: TCTCGCGAG; match class: 1 0.00523505855548913 10488 30 26 0.866666666666667 0.0024790236460717
TF TF:M09905 Factor: SAP-1; motif: NNCCGGAAGTGN 0.00526797591131377 8273 30 23 0.766666666666667 0.00278012812764414
TF TF:M00460_1 Factor: STAT5A; motif: TTCCNRGAANNNNNNTTCCNNGRR; match class: 1 0.00526797591131377 2567 14 8 0.571428571428571 0.00311647837943124
TF TF:M08266_1 Factor: ER71:Pax-5; motif: ACCGGAACYACGCWTSANTG; match class: 1 0.00529193503647821 8979 30 24 0.8 0.00267290344136318
TF TF:M02059_1 Factor: ELK-1; motif: ACCGGAAGTN; match class: 1 0.00561719656380203 3759 30 15 0.5 0.00399042298483639
TF TF:M08345 Factor: HOXB2:PEA3; motif: ACCGGAAATGRN 0.00561719656380203 8027 19 16 0.842105263157895 0.0019932727046219
TF TF:M08222 Factor: Elk-1:HOXB13; motif: ACCGGAAGTNGTAAAN 0.00561719656380203 7653 30 22 0.733333333333333 0.00287468966418398
TF TF:M01229_1 Factor: GTF2IRD1-isoform2; motif: GGGATTRNR; match class: 1 0.00566634162707902 9375 12 12 1 0.00128
TF TF:M00981 Factor: CREB,; motif: NTGACGTNA 0.00579517178925581 8345 30 23 0.766666666666667 0.00275614140203715
TF TF:M08226 Factor: Elk-1:Pax-9; motif: ACCGGAACYACGCWYSANTG 0.00579517178925581 12039 18 18 1 0.00149514079242462
TF TF:M11320_1 Factor: C/EBPdelta; motif: NRTTGCGYAAYN; match class: 1 0.00603453142460084 2586 25 11 0.44 0.00425367362722351
TF TF:M11447 Factor: Elf-1; motif: NAMCCGGAAGTN 0.00603453142460084 7703 30 22 0.733333333333333 0.00285603011813579
TF TF:M11420 Factor: ER81; motif: NACCGGAAGTN 0.00609146355330018 3210 21 11 0.523809523809524 0.00342679127725857
TF TF:M09901 Factor: nerf; motif: NNNCCGGAAGTGN 0.00631699403915518 5352 30 18 0.6 0.00336322869955157
TF TF:M08632 Factor: TEF-3:Dlx-2; motif: RMATWCYNNNYAATTA 0.00631699403915518 600 18 5 0.277777777777778 0.00833333333333333
TF TF:M10849_1 Factor: Cdx-2; motif: NRTCGTAANNNN; match class: 1 0.00631699403915518 4497 29 16 0.551724137931034 0.00355792750722704
TF TF:M08226_1 Factor: Elk-1:Pax-9; motif: ACCGGAACYACGCWYSANTG; match class: 1 0.00640956522496781 5604 29 18 0.620689655172414 0.00321199143468951
TF TF:M01167 Factor: SAP-1a; motif: NACCGGAAGTV 0.006495156399447 1948 7 5 0.714285714285714 0.00256673511293634
TF TF:M10632 Factor: Nkx2-8; motif: STCGTTGAN 0.00707381624960073 4871 30 17 0.566666666666667 0.00349004311229727
TF TF:M01876_1 Factor: GABP-beta; motif: ASMGGAAGKGN; match class: 1 0.0072774062085335 197 29 4 0.137931034482759 0.0203045685279188
TF TF:M11442 Factor: Net; motif: NACCGGAAGTN 0.00740882486014369 2012 7 5 0.714285714285714 0.00248508946322068
TF TF:M06079 Factor: ZNF276; motif: NNGGAAAGACGC 0.00744582414272884 90 25 3 0.12 0.0333333333333333
TF TF:M11430_1 Factor: PEA3; motif: NACCGGAAGTN; match class: 1 0.00744582414272884 4902 30 17 0.566666666666667 0.00346797225622195
TF TF:M08313_1 Factor: GCMa:PEA3; motif: ATRCGGGCGGAAGTR; match class: 1 0.00765221135091009 9721 29 24 0.827586206896552 0.00246888180228372
TF TF:M01214_1 Factor: ESE-1; motif: NSMGGAARTN; match class: 1 0.00780208586967672 2176 30 11 0.366666666666667 0.00505514705882353
TF TF:M02055_1 Factor: ESE-1; motif: NSMGGAARTN; match class: 1 0.00780208586967672 2176 30 11 0.366666666666667 0.00505514705882353
TF TF:M02053 Factor: ELF1; motif: NCCGGAARTN 0.00780208586967672 6033 30 19 0.633333333333333 0.00314934526769435
TF TF:M09904_1 Factor: Elk-1; motif: RCCGGAAGTGN; match class: 1 0.00878675426026804 2743 25 11 0.44 0.004010207801677
TF TF:M08637 Factor: TEF-3:Erg; motif: ACCGGAAATRNNNNNCATWCC 0.00878675426026804 4382 25 14 0.56 0.00319488817891374
TF TF:M02044_1 Factor: YY1; motif: GCCGCCATTTTG; match class: 1 0.00878675426026804 1198 29 8 0.275862068965517 0.00667779632721202
TF TF:M11413 Factor: ER71; motif: NACCGGAARTN 0.00878675426026804 2111 7 5 0.714285714285714 0.00236854571293226
TF TF:M04711 Factor: PU.1; motif: ACTTCCTCT 0.00878675426026804 1712 12 6 0.5 0.00350467289719626
TF TF:M12275 Factor: YY1; motif: NGCCGCCATYTTGN 0.00957891787188831 7043 29 20 0.689655172413793 0.00283969899190686
TF TF:M10632_1 Factor: Nkx2-8; motif: STCGTTGAN; match class: 1 0.00959804892570146 831 15 5 0.333333333333333 0.00601684717208183
TF TF:M08510 Factor: TEF-3:Fli-1; motif: ACCGGAAATGCC 0.00972949644141395 7360 30 21 0.7 0.00285326086956522
TF TF:M08225_1 Factor: Elk-1:Pax-5; motif: ACCGGAACYACGCWTSANYG; match class: 1 0.00997627570470989 7993 9 9 1 0.00112598523708245
TF TF:M11450 Factor: Elf-1; motif: NANSCGGAAGTR 0.00997627570470989 5601 30 18 0.6 0.00321371183717193
TF TF:M10785 Factor: hoxa9; motif: RTCGTWANNN 0.00997627570470989 5632 9 8 0.888888888888889 0.00142045454545455
TF TF:M11415 Factor: GABP-alpha; motif: NRCCGGAAGTN 0.0108105925871322 3257 19 10 0.526315789473684 0.00307031010132023
TF TF:M02066_1 Factor: PEA3; motif: RCCGGAAGYN; match class: 1 0.0108351740094273 2283 30 11 0.366666666666667 0.00481822163819536
TF TF:M02064_1 Factor: c-ets-2; motif: ACCGGAWRTN; match class: 1 0.0114109623596596 4592 30 16 0.533333333333333 0.00348432055749129
TF TF:M11419 Factor: ER81; motif: NNCCGGAWGYN 0.0120273786957406 5699 21 14 0.666666666666667 0.00245657132830321
TF TF:M11418 Factor: ER81; motif: NRCMGGAWGNN 0.0122457244506432 3978 22 12 0.545454545454545 0.00301659125188537
TF TF:M00017 Factor: ATF; motif: CNSTGACGTNNNYC 0.0123111329888406 7226 27 19 0.703703703703704 0.00262939385552173
TF TF:M11983_1 Factor: NFATc2; motif: NTTTCCGCGGAAAN; match class: 1 0.0123194813622293 7294 16 13 0.8125 0.0017822868110776
TF TF:M11421 Factor: ER81; motif: NACCGGAAGTN 0.0127785764360972 2341 7 5 0.714285714285714 0.00213583938487826
TF TF:M01660 Factor: GABP-alpha; motif: CTTCCK 0.0127918322539414 11116 30 26 0.866666666666667 0.00233897085282476
TF TF:M03924 Factor: YY1; motif: NNCGCCATTNN 0.0131387162327082 10084 29 24 0.827586206896552 0.00238000793335978
TF TF:M02073_1 Factor: Fli-1; motif: ACCGGAAGYN; match class: 1 0.0133784244681179 1488 6 4 0.666666666666667 0.00268817204301075
TF TF:M02072 Factor: Pet-1; motif: ACCGGAWRTN 0.0137914463381433 2395 7 5 0.714285714285714 0.00208768267223382
TF TF:M09900 Factor: Elf-1; motif: NNANCCGGAAGTGS 0.0137914463381433 5219 30 17 0.566666666666667 0.00325732899022801
TF TF:M11450_1 Factor: Elf-1; motif: NANSCGGAAGTR; match class: 1 0.0142278149280808 1315 29 8 0.275862068965517 0.00608365019011407
TF TF:M11448 Factor: Elf-1; motif: NANGCGGAAGTN 0.0143716923850825 7600 30 21 0.7 0.00276315789473684
TF TF:M11431 Factor: PEA3; motif: NTCGTAAATGCA 0.0143716923850825 10559 24 21 0.875 0.00198882469930865
TF TF:M11300_1 Factor: B-ATF; motif: NNATGACACN; match class: 1 0.0145019078570931 2584 20 9 0.45 0.00348297213622291
TF TF:M03967 Factor: ELF3; motif: WACCCGGAAGTAN 0.0145728297268188 7610 8 8 1 0.00105124835742444
TF TF:M10104 Factor: YY1; motif: CAARATGGCGGC 0.0145728297268188 6071 29 18 0.620689655172414 0.00296491517048262
TF TF:M08220 Factor: Elk-1:HOXA3; motif: ACCGGWAATKRNNTNWCNNATTAN 0.0154805776368534 12140 21 20 0.952380952380952 0.00164744645799012
TF TF:M11437 Factor: SAP-1; motif: NRCCGGAWGYN 0.0156281458844455 2788 19 9 0.473684210526316 0.00322812051649928
TF TF:M04517 Factor: E2F2; motif: AAAATGGCGCCATTTT 0.0162192981921054 9190 28 22 0.785714285714286 0.00239390642002176
TF TF:M11449 Factor: Elf-1; motif: NANCCGGAAGTN 0.0176997549498312 4305 7 6 0.857142857142857 0.00139372822299652
TF TF:M11439 Factor: Net; motif: NRCCGGAAGTN 0.0178536785218876 2568 7 5 0.714285714285714 0.00194704049844237
TF TF:M02069 Factor: Erm; motif: ACCGGAAGTN 0.0187367957223881 6892 19 14 0.736842105263158 0.002031340684852
TF TF:M11407 Factor: Pet-1; motif: NACCGGAAGTN 0.0188927902864569 772 19 5 0.263157894736842 0.00647668393782383
TF TF:M11438_1 Factor: SAP-1; motif: NTCGTAAATGCN; match class: 1 0.0191744799446418 1191 26 7 0.269230769230769 0.00587741393786734
TF TF:M08451_1 Factor: Elk-1:HOXA1; motif: ACCGGAAGTAATTA; match class: 1 0.0191744799446418 2584 29 11 0.379310344827586 0.00425696594427245
TF TF:M11460 Factor: nerf; motif: NANSCGGAAGTN 0.0199610851401595 736 30 6 0.2 0.00815217391304348
TF TF:M11320 Factor: C/EBPdelta; motif: NRTTGCGYAAYN 0.0199610851401595 5477 25 15 0.6 0.00273872557969691
TF TF:M11414 Factor: GABP-alpha; motif: NACCGGAAGTN 0.0199610851401595 2907 19 9 0.473684210526316 0.00309597523219814
TF TF:M11696 Factor: MEF-2B1; motif: CCNWATWWRG 0.0199610851401595 2268 28 10 0.357142857142857 0.00440917107583774
TF TF:M10169 Factor: ZNF76; motif: RNNGCMTKCTGGGARNTGTAGT 0.0199610851401595 1378 23 7 0.304347826086957 0.00507982583454282
TF TF:M11375 Factor: Spi-B; motif: NAWGCGGAAGTN 0.0199969368880022 2608 29 11 0.379310344827586 0.00421779141104294
TF TF:M03966 Factor: ELF1; motif: AACCCGGAAGTR 0.021202007713155 6610 30 19 0.633333333333333 0.00287443267776097
TF TF:M01861 Factor: ATF-1; motif: TNACGTCAN 0.0212815787823265 6294 29 18 0.620689655172414 0.00285986653956149
TF TF:M11527 Factor: E2F-3; motif: NTTTTGGCGCCAAAAN 0.0219476348633595 6929 29 19 0.655172413793103 0.00274209842690143
TF TF:M06322 Factor: ZNF181; motif: NCGGAAAGACGC 0.0224968125527869 149 25 3 0.12 0.0201342281879195
TF TF:M03791 Factor: GABPalpha_GABPbeta; motif: CTTCCKGY 0.0224968125527869 2969 19 9 0.473684210526316 0.00303132367800606
TF TF:M09905_1 Factor: SAP-1; motif: NNCCGGAAGTGN; match class: 1 0.0224968125527869 2989 30 12 0.4 0.0040147206423553
TF TF:M10783 Factor: hoxa9; motif: RTCGTWAANN 0.0231095877994215 1897 3 3 1 0.00158144438587243
TF TF:M00793 Factor: YY1; motif: GCCATNTTN 0.02331766032618 5186 29 16 0.551724137931034 0.00308522946394138
TF TF:M03990 Factor: GABPA; motif: ACCGGAAGTN 0.0233346616675285 5258 19 12 0.631578947368421 0.00228223659186002
TF TF:M11454 Factor: ELFR; motif: NANGMGGAAGTN 0.0235209168341106 1072 30 7 0.233333333333333 0.00652985074626866
TF TF:M09966 Factor: Kaiso; motif: SARNYCTCGCGAGAN 0.0235209168341106 2356 15 7 0.466666666666667 0.00297113752122241
TF TF:M08266 Factor: ER71:Pax-5; motif: ACCGGAACYACGCWTSANTG 0.0235209168341106 14377 30 29 0.966666666666667 0.0020171106628643
TF TF:M00074 Factor: c-Ets-1(p54); motif: NNACMGGAWRTNN 0.0238872055206222 3484 30 13 0.433333333333333 0.00373134328358209
TF TF:M00485_1 Factor: Nkx2-2; motif: TTAAGTRSTT; match class: 1 0.0241570668112333 304 29 4 0.137931034482759 0.0131578947368421
TF TF:M10938 Factor: CHX10; motif: GCYAATTAY 0.0241570668112333 328 27 4 0.148148148148148 0.0121951219512195
TF TF:M11457 Factor: nerf; motif: NANGCGGAAGTR 0.0242023251841396 1082 30 7 0.233333333333333 0.00646950092421442
TF TF:M02058 Factor: SAP1A; motif: NCCGGAARYN 0.0242509550291298 842 19 5 0.263157894736842 0.00593824228028504
TF TF:M12275_1 Factor: YY1; motif: NGCCGCCATYTTGN; match class: 1 0.0245819517171112 1600 27 8 0.296296296296296 0.005
TF TF:M08205 Factor: E2F-1:Elk-1; motif: SGCGCSNNAMCGGAAGT 0.0245819517171112 14429 30 29 0.966666666666667 0.00200984129184282
TF TF:M00007_1 Factor: Elk-1; motif: NAAACMGGAAGTNCVH; match class: 1 0.02493346140809 1119 9 4 0.444444444444444 0.00357462019660411
TF TF:M01124 Factor: Oct-4; motif: ATTGWSWTGCWAAWN 0.0256308394378598 6034 26 16 0.615384615384615 0.00265164070268479
TF TF:M03958_1 Factor: E2F2; motif: AAAAATGGCGCCAAAAWG; match class: 1 0.0256308394378598 4181 26 13 0.5 0.00310930399425975
TF TF:M04016 Factor: IRF5; motif: CCGAAACCGAAACY 0.0260311340010314 314 29 4 0.137931034482759 0.0127388535031847
TF TF:M07386 Factor: Lmx1; motif: RDNTAATT 0.0265291293912474 6123 28 17 0.607142857142857 0.00277641678915564
TF TF:M11983 Factor: NFATc2; motif: NTTTCCGCGGAAAN 0.0275645345614889 8048 16 13 0.8125 0.00161530815109344
TF TF:M11316_1 Factor: C/EBPbeta; motif: NRTTGCGYAAYN; match class: 1 0.0276645451829205 2743 25 10 0.4 0.00364564345607
TF TF:M02052_1 Factor: EHF; motif: CSCGGAARTN; match class: 1 0.027848524561987 4056 30 14 0.466666666666667 0.00345167652859961
TF TF:M08982 Factor: YY1; motif: NAANATGGCGNNN 0.0279417267577566 7125 29 19 0.655172413793103 0.00266666666666667
TF TF:M00953 Factor: AR; motif: NNNGNRRGNACANNGTGTTCTNNNNNN 0.0279417267577566 2415 28 10 0.357142857142857 0.0041407867494824
TF TF:M11301_1 Factor: B-ATF; motif: NNAYGACACN; match class: 1 0.0279417267577566 1972 23 8 0.347826086956522 0.00405679513184584
TF TF:M04714_1 Factor: Elf-1; motif: ACTTCCGGG; match class: 1 0.0279417267577566 2659 30 11 0.366666666666667 0.00413689356901091
TF TF:M11425_1 Factor: PEA3; motif: NACCGGAAGTN; match class: 1 0.0282865403456418 2330 29 10 0.344827586206897 0.00429184549356223
TF TF:M08760_1 Factor: ETV7; motif: NNSCGGAAGTR; match class: 1 0.0284827284544201 326 29 4 0.137931034482759 0.0122699386503067
TF TF:M09606 Factor: nerf; motif: NRRNSCGGAAGNRNNNN 0.0287731430545067 6249 30 18 0.6 0.0028804608737398
TF TF:M09605 Factor: Elf-1; motif: NAANCMGGAAGTGN 0.0292884178779533 5778 10 8 0.8 0.00138456213222568
TF TF:M04518_1 Factor: E2F-4; motif: AATGGCGCCAAA; match class: 1 0.0292884178779533 1054 10 4 0.4 0.00379506641366224
TF TF:M00250 Factor: Gfi-1; motif: NNNNNNNAAATCACWGYNNNNNNN 0.0292884178779533 1032 5 3 0.6 0.00290697674418605
TF TF:M04765_1 Factor: Pasx-5; motif: GTCACGSTT; match class: 1 0.0292884178779533 4135 18 10 0.555555555555556 0.00241837968561064
TF TF:M04696 Factor: YY1; motif: GCCGCCATNTTGNNNNNGGNCN 0.0292884178779533 7819 29 20 0.689655172413793 0.00255787185062028
TF TF:M11427_1 Factor: PEA3; motif: NACCGGAAGTN; match class: 1 0.0292884178779533 4606 30 15 0.5 0.00325662179765523
TF TF:M04698_1 Factor: GABP-alpha; motif: CACTTCCGG; match class: 1 0.0301682191270577 576 29 5 0.172413793103448 0.00868055555555556
TF TF:M08637_1 Factor: TEF-3:Erg; motif: ACCGGAAATRNNNNNCATWCC; match class: 1 0.0303231871824968 592 17 4 0.235294117647059 0.00675675675675676
TF TF:M10795 Factor: HOXA10; motif: NGTCGTAAAAN 0.0303638939914534 6913 9 8 0.888888888888889 0.0011572399826414
TF TF:M02054 Factor: ELF2; motif: CCCGGAARYN 0.0309486392739254 3066 7 5 0.714285714285714 0.00163078930202218
TF TF:M00425_1 Factor: E2F; motif: TTTCGCGC; match class: 1 0.0313437545464682 5355 5 5 1 0.000933706816059757
TF TF:M11883_1 Factor: pax-6; motif: NYACGCNTSRNYGCNYN; match class: 1 0.0313437545464682 7768 7 7 1 0.000901132852729145
TF TF:M10625_1 Factor: Nkx3-2; motif: NTCGTTAN; match class: 1 0.0315102621274496 1314 20 6 0.3 0.0045662100456621
TF TF:M07483 Factor: CXXC1; motif: KNRNAMCGMWAAMNN 0.0318690581237124 1318 20 6 0.3 0.00455235204855842
TF TF:M11452_1 Factor: Elf-1; motif: NANGCGGAAGTR; match class: 1 0.0321266515215132 1696 7 4 0.571428571428571 0.00235849056603774
TF TF:M10650_1 Factor: HOX11L2; motif: NAATTGNNNNNNNNNNNNNCAATTN; match class: 1 0.0321266515215132 199 23 3 0.130434782608696 0.0150753768844221
TF TF:M11014_1 Factor: ISL2; motif: NCAMTTAN; match class: 1 0.032392530500923 422 24 4 0.166666666666667 0.00947867298578199
TF TF:M00917 Factor: CREB; motif: CNNTGACGTMA 0.0326626684683565 5578 26 15 0.576923076923077 0.00268913589100036
TF TF:M07260 Factor: Ikaros; motif: TGGGAGN 0.033514120503802 13523 17 17 1 0.00125711750351253
TF TF:M04822 Factor: c-ets-1; motif: GGAGTTG 0.0341761184230277 5496 5 5 1 0.000909752547307132
TF TF:M08418_1 Factor: TEF-3:Elk-1; motif: RMATWCCGGAWGT; match class: 1 0.0341761184230277 5247 30 16 0.533333333333333 0.00304936153992758
TF TF:M00425 Factor: E2F; motif: TTTCGCGC 0.03431744060741 11043 11 11 1 0.000996106130580458
TF TF:M01281_1 Factor: NFATc2; motif: GGAAAA; match class: 1 0.0343845318748965 11109 30 25 0.833333333333333 0.00225042758124044
TF TF:M03555_1 Factor: NFATc2; motif: GGAAAA; match class: 1 0.0343845318748965 11109 30 25 0.833333333333333 0.00225042758124044
TF TF:M01886_1 Factor: NFATc3; motif: GGAAAA; match class: 1 0.0343845318748965 11109 30 25 0.833333333333333 0.00225042758124044
TF TF:M11527_1 Factor: E2F-3; motif: NTTTTGGCGCCAAAAN; match class: 1 0.035735172223641 6697 29 18 0.620689655172414 0.00268777064357175
TF TF:M12276_1 Factor: YY1; motif: NGCCATYTTKGRCNWWNNGTGCK; match class: 1 0.0358427129834796 3614 24 11 0.458333333333333 0.003043718871057
TF TF:M01078_1 Factor: c-Ets-1; motif: NNNRCCGGAWRYNNNN; match class: 1 0.0358427129834796 2448 29 10 0.344827586206897 0.00408496732026144
TF TF:M03990_1 Factor: GABPA; motif: ACCGGAAGTN; match class: 1 0.036166153086145 1206 30 7 0.233333333333333 0.00580431177446103
TF TF:M11406 Factor: Pet-1; motif: NACCGGAAGTN 0.0363642512068879 1301 21 6 0.285714285714286 0.00461183704842429
TF TF:M08759_1 Factor: c-Ets-2; motif: NCCGGAAGTG; match class: 1 0.036626628124805 2915 29 11 0.379310344827586 0.00377358490566038
TF TF:M11384 Factor: ESE-1; motif: ACCCGGAAGTRNNNNNNNWWWWW 0.0373483144536077 3272 30 12 0.4 0.00366748166259169
TF TF:M10880_1 Factor: Alx-4; motif: NNCRTTAN; match class: 1 0.0374397917651222 2683 27 10 0.37037037037037 0.00372717107715244
TF TF:M10578 Factor: Barhl-1; motif: NTAAACGN 0.0374397917651222 6099 10 8 0.8 0.00131169044105591
TF TF:M08415_1 Factor: TEF-3:Elf-1; motif: RGAATGCGGAAGTN; match class: 1 0.0383271313347388 2752 8 5 0.625 0.00181686046511628
TF TF:M10797_1 Factor: HOXA10; motif: RGTCGTAAAAN; match class: 1 0.0393522393229714 1128 17 5 0.294117647058824 0.00443262411347518
TF TF:M11431_1 Factor: PEA3; motif: NTCGTAAATGCA; match class: 1 0.0395471100426351 4298 24 12 0.5 0.0027919962773383
TF TF:M01798 Factor: RPC155; motif: TCMNGRGTTCRAGWCC 0.0395471100426351 975 12 4 0.333333333333333 0.0041025641025641
TF TF:M02097 Factor: LHX3; motif: ATTAAW 0.0401102014473577 11840 29 25 0.862068965517241 0.00211148648648649
TF TF:M03803 Factor: Sox-17; motif: TTGTYY 0.0401102014473577 15590 26 26 1 0.00166773572803079
TF TF:M08232 Factor: Elk-1:TEF; motif: RCCGGAAGTTACGTAAN 0.0401102014473577 6188 10 8 0.8 0.00129282482223659
TF TF:M08225 Factor: Elk-1:Pax-5; motif: ACCGGAACYACGCWTSANYG 0.0401102014473577 14039 18 18 1 0.00128214260274948
TF TF:M11881_1 Factor: pax-6; motif: NYACGCNTSANYGCNYN; match class: 1 0.0420559443778921 7158 30 19 0.633333333333333 0.0026543727298128
TF TF:M07370 Factor: YY1; motif: NNNNAARATGGNNNN 0.0421881844325692 5811 19 12 0.631578947368421 0.00206504904491482
TF TF:M08767_1 Factor: HES-1; motif: GNCACGTGNC; match class: 1 0.0421881844325692 7709 19 14 0.736842105263158 0.00181605915164094
TF TF:M08423_1 Factor: TEF-3:ER81; motif: ACCGGAAATRCC; match class: 1 0.0429208378146925 654 29 5 0.172413793103448 0.00764525993883792
TF TF:M07456 Factor: HOX; motif: TTWATKNN 0.0445450615985679 2040 30 9 0.3 0.00441176470588235
TF TF:M09607_1 Factor: SAP-1; motif: ACCGGAAGTNN; match class: 1 0.0454383035536964 977 29 6 0.206896551724138 0.00614124872057318
TF TF:M02077 Factor: Spic; motif: NGNGGAASTN 0.0455028806546291 8354 25 18 0.72 0.00215465645199904
TF TF:M04609_1 Factor: AP-3; motif: TKGAAAKN; match class: 1 0.0457130570929028 655 9 3 0.333333333333333 0.00458015267175573
TF TF:M11754 Factor: HNF-4alpha; motif: RRGGTCAAAGGTCAN 0.0463382023205526 1336 29 7 0.241379310344828 0.00523952095808383
TF TF:M08767 Factor: HES-1; motif: GNCACGTGNC 0.0472407566073504 7813 19 14 0.736842105263158 0.00179188531933956
TF TF:M11528 Factor: E2F-2; motif: NTTTTGGCGCCAWWWN 0.0474037802946667 10373 29 23 0.793103448275862 0.00221729490022173
TF TF:M02071_1 Factor: ETV7; motif: NCCGGAANNN; match class: 1 0.0490749258233496 4465 6 5 0.833333333333333 0.00111982082866741
TF TF:M02011 Factor: HES-1; motif: GSCACGMGMC 0.0490749258233496 4259 19 10 0.526315789473684 0.00234796900680911
WP WP:WP477 Cytoplasmic Ribosomal Proteins 2.2249300958863e-59 90 30 30 1 0.333333333333333

pEpiTp12 transcription factor target enrichment of top program genes

TF enrichment of pEpiTp12
Possible regulators of activation of pEpiTp12 in epithelial cells. (Left) pearson correlation of TF expression and gene expression program activatity in Epithelial cells, (right) negative log p-value for enrichment of TF binding sites among top uniqueness weighted genes for the gene program. Blue bars indicate significant TFs meeting the following criteria: FDR<0.1, overlap > 2, Corr. R > 0, permutation based p-value < 0.05.