pEpiTd14 program activity among Epithelial cells

Activation of pEpiTd14
pEpiTd14 gene program activation in Epithelial cells. (Top) Activation of program across all epithelial cells. (Bottom) Activation in MMRd (left), MMRp (middle), and normal epithelial cells (right).

Epithelial cell compositional overview

Overview of epithelial cell composition
Overview of epithelial cell composition. A tSNE plot colored by: (left) MMR status of epithelial cells, (middle) specimen, (righ) epithelial cell sub-type.
Gene program activation of pEpiTd14 by different cell subtypes
pEpiTd14 gene program activation among cells of different subtypes (Epithelial cells).

pEpiTd14 top program genes

Top genes of pEpiTd14 program
Bar plots showing the top genes for each gene program, ranked by (left) unique weights, (right) raw weights.

pEpiTd14 gene-set enrichment of top program genes (using g-profiler)

GSEA wth gene profiler of pEpiTd14
pEpiTd14 gene-set enrichment summary using g-profiler webtool.
Source termID Name Padj Tsize Qsize Overlap Precision Recall
GO:BP GO:0045934 negative regulation of nucleobase-containing compound metabolic process 0.019891538334192 1548 112 24 0.214285714285714 0.0155038759689922
GO:BP GO:0048024 regulation of mRNA splicing, via spliceosome 0.019891538334192 119 10 3 0.3 0.0252100840336134
GO:BP GO:0009746 response to hexose 0.019891538334192 209 34 5 0.147058823529412 0.0239234449760766
GO:BP GO:0009749 response to glucose 0.019891538334192 202 34 5 0.147058823529412 0.0247524752475248
GO:BP GO:0051253 negative regulation of RNA metabolic process 0.019891538334192 1445 112 23 0.205357142857143 0.015916955017301
GO:BP GO:0034284 response to monosaccharide 0.019891538334192 215 34 5 0.147058823529412 0.0232558139534884
GO:BP GO:0050684 regulation of mRNA processing 0.0221113892929034 158 10 3 0.3 0.0189873417721519
GO:BP GO:0009743 response to carbohydrate 0.0221113892929034 243 34 5 0.147058823529412 0.0205761316872428
GO:BP GO:0043484 regulation of RNA splicing 0.0221113892929034 160 10 3 0.3 0.01875
GO:BP GO:0031327 negative regulation of cellular biosynthetic process 0.0284164833345029 1707 112 23 0.205357142857143 0.0134739308728764
GO:BP GO:0035107 appendage morphogenesis 0.0284164833345029 141 38 4 0.105263157894737 0.0283687943262411
GO:BP GO:0051726 regulation of cell cycle 0.0284164833345029 1236 39 10 0.256410256410256 0.00809061488673139
GO:BP GO:0031324 negative regulation of cellular metabolic process 0.0284164833345029 2719 112 32 0.285714285714286 0.0117690327326223
GO:BP GO:0051172 negative regulation of nitrogen compound metabolic process 0.0284164833345029 2518 112 30 0.267857142857143 0.0119142176330421
GO:BP GO:0008380 RNA splicing 0.0284164833345029 456 47 7 0.148936170212766 0.0153508771929825
GO:BP GO:0035108 limb morphogenesis 0.0284164833345029 141 38 4 0.105263157894737 0.0283687943262411
GO:BP GO:1902369 negative regulation of RNA catabolic process 0.0284164833345029 71 79 4 0.0506329113924051 0.0563380281690141
GO:BP GO:1902373 negative regulation of mRNA catabolic process 0.0284164833345029 60 79 4 0.0506329113924051 0.0666666666666667
GO:BP GO:0071322 cellular response to carbohydrate stimulus 0.0299778505602779 148 115 6 0.0521739130434783 0.0405405405405405
GO:BP GO:2000113 negative regulation of cellular macromolecule biosynthetic process 0.0299778505602779 1628 112 22 0.196428571428571 0.0135135135135135
GO:BP GO:0048523 negative regulation of cellular process 0.0299778505602779 5139 141 59 0.418439716312057 0.0114808328468574
GO:BP GO:0010558 negative regulation of macromolecule biosynthetic process 0.0299778505602779 1639 112 22 0.196428571428571 0.0134228187919463
GO:BP GO:0009890 negative regulation of biosynthetic process 0.0299778505602779 1740 112 23 0.205357142857143 0.0132183908045977
GO:BP GO:0000398 mRNA splicing, via spliceosome 0.0299778505602779 361 32 5 0.15625 0.0138504155124654
GO:BP GO:0000377 RNA splicing, via transesterification reactions with bulged adenosine as nucleophile 0.0299778505602779 361 32 5 0.15625 0.0138504155124654
GO:BP GO:0048255 mRNA stabilization 0.0299778505602779 53 48 3 0.0625 0.0566037735849057
GO:BP GO:0000375 RNA splicing, via transesterification reactions 0.0303364986759268 364 32 5 0.15625 0.0137362637362637
GO:BP GO:0048736 appendage development 0.0312024130731922 176 38 4 0.105263157894737 0.0227272727272727
GO:BP GO:1902679 negative regulation of RNA biosynthetic process 0.0312024130731922 1341 112 19 0.169642857142857 0.0141685309470544
GO:BP GO:1903507 negative regulation of nucleic acid-templated transcription 0.0312024130731922 1339 112 19 0.169642857142857 0.0141896938013443
GO:BP GO:0045892 negative regulation of transcription, DNA-templated 0.0312024130731922 1337 112 19 0.169642857142857 0.0142109199700823
GO:BP GO:0060173 limb development 0.0312024130731922 176 38 4 0.105263157894737 0.0227272727272727
GO:BP GO:0043489 RNA stabilization 0.0312655860623744 61 48 3 0.0625 0.0491803278688525
GO:BP GO:1903311 regulation of mRNA metabolic process 0.0318401766875188 356 21 4 0.19047619047619 0.0112359550561798
GO:BP GO:1903312 negative regulation of mRNA metabolic process 0.0318401766875188 91 79 4 0.0506329113924051 0.043956043956044
GO:BP GO:0007010 cytoskeleton organization 0.0349314819526923 1423 93 17 0.182795698924731 0.0119465917076599
GO:BP GO:0030855 epithelial cell differentiation 0.0349314819526923 798 136 15 0.110294117647059 0.018796992481203
GO:BP GO:0046546 development of primary male sexual characteristics 0.0373758271547932 143 100 5 0.05 0.034965034965035
GO:BP GO:0008584 male gonad development 0.0373758271547932 142 100 5 0.05 0.0352112676056338
GO:BP GO:0000302 response to reactive oxygen species 0.0373758271547932 237 123 7 0.0569105691056911 0.029535864978903
GO:BP GO:0044773 mitotic DNA damage checkpoint 0.0409647522129198 106 38 3 0.0789473684210526 0.0283018867924528
GO:BP GO:0006913 nucleocytoplasmic transport 0.0409647522129198 354 12 3 0.25 0.00847457627118644
GO:BP GO:0051169 nuclear transport 0.0413366531196183 357 12 3 0.25 0.00840336134453781
GO:BP GO:0010564 regulation of cell cycle process 0.0421066986767059 809 39 7 0.179487179487179 0.00865265760197775
GO:BP GO:1901983 regulation of protein acetylation 0.0429052017589171 78 123 4 0.032520325203252 0.0512820512820513
GO:BP GO:1901700 response to oxygen-containing compound 0.0429052017589171 1739 25 8 0.32 0.00460034502587694
GO:BP GO:0071331 cellular response to hexose stimulus 0.0429052017589171 139 115 5 0.0434782608695652 0.0359712230215827
GO:BP GO:0071326 cellular response to monosaccharide stimulus 0.0429052017589171 140 115 5 0.0434782608695652 0.0357142857142857
GO:BP GO:0071333 cellular response to glucose stimulus 0.0429052017589171 137 115 5 0.0434782608695652 0.0364963503649635
GO:BP GO:0016071 mRNA metabolic process 0.0429052017589171 874 94 12 0.127659574468085 0.0137299771167048
GO:BP GO:0044774 mitotic DNA integrity checkpoint 0.0429052017589171 112 38 3 0.0789473684210526 0.0267857142857143
GO:BP GO:0007049 cell cycle 0.0429052017589171 1902 39 11 0.282051282051282 0.00578338590956887
GO:BP GO:0010628 positive regulation of gene expression 0.0437567053723047 1160 22 6 0.272727272727273 0.00517241379310345
GO:BP GO:0046661 male sex differentiation 0.0437567053723047 163 100 5 0.05 0.0306748466257669
GO:BP GO:0031056 regulation of histone modification 0.0437567053723047 150 31 3 0.0967741935483871 0.02
GO:BP GO:0048713 regulation of oligodendrocyte differentiation 0.0442886944740577 38 123 3 0.024390243902439 0.0789473684210526
GO:BP GO:0000122 negative regulation of transcription by RNA polymerase II 0.0445377789728686 901 131 15 0.114503816793893 0.0166481687014428
GO:BP GO:0018023 peptidyl-lysine trimethylation 0.0447279054885599 47 100 3 0.03 0.0638297872340425
GO:BP GO:0006397 mRNA processing 0.0448201640543676 532 32 5 0.15625 0.0093984962406015
GO:BP GO:0044770 cell cycle phase transition 0.0483294615156627 658 39 6 0.153846153846154 0.00911854103343465
GO:BP GO:0048519 negative regulation of biological process 0.0483294615156627 5757 141 61 0.432624113475177 0.0105957964217474
GO:BP GO:0018205 peptidyl-lysine modification 0.0483294615156627 405 43 5 0.116279069767442 0.0123456790123457
GO:BP GO:1903047 mitotic cell cycle process 0.0483294615156627 911 94 12 0.127659574468085 0.013172338090011
GO:BP GO:0043266 regulation of potassium ion transport 0.0483294615156627 110 45 3 0.0666666666666667 0.0272727272727273
GO:BP GO:0006473 protein acetylation 0.0489897539709527 205 123 6 0.0487804878048781 0.0292682926829268
GO:CC GO:0005634 nucleus 0.00173158058943917 7592 138 81 0.58695652173913 0.0106691253951528
GO:CC GO:0005654 nucleoplasm 0.00173158058943917 4102 136 51 0.375 0.0124329595319356
GO:CC GO:0005667 transcription regulator complex 0.00173158058943917 432 131 13 0.099236641221374 0.0300925925925926
GO:CC GO:0017053 transcription repressor complex 0.00173158058943917 77 131 6 0.0458015267175573 0.0779220779220779
GO:CC GO:0016604 nuclear body 0.00201284026944596 816 47 10 0.212765957446809 0.0122549019607843
GO:CC GO:0043229 intracellular organelle 0.00224028584183514 12491 120 99 0.825 0.00792570650868625
GO:CC GO:0031981 nuclear lumen 0.00224028584183514 4444 123 49 0.398373983739837 0.011026102610261
GO:CC GO:0005622 intracellular anatomical structure 0.00577689354541855 14790 102 94 0.92156862745098 0.00635564570655849
GO:CC GO:0043231 intracellular membrane-bounded organelle 0.00577689354541855 11296 120 91 0.758333333333333 0.00805594900849858
GO:CC GO:0043227 membrane-bounded organelle 0.00889155304296723 12858 40 37 0.925 0.0028775859387152
GO:CC GO:0031974 membrane-enclosed lumen 0.0119894905047936 5565 32 19 0.59375 0.00341419586702606
GO:CC GO:0043233 organelle lumen 0.0119894905047936 5565 32 19 0.59375 0.00341419586702606
GO:CC GO:0070013 intracellular organelle lumen 0.0119894905047936 5402 123 53 0.430894308943089 0.00981118104405776
GO:CC GO:0043232 intracellular non-membrane-bounded organelle 0.02974157131327 5338 112 47 0.419642857142857 0.00880479580367179
GO:CC GO:0043228 non-membrane-bounded organelle 0.02974157131327 5346 112 47 0.419642857142857 0.00879161990273101
GO:CC GO:0034451 centriolar satellite 0.0306908147513776 107 39 3 0.0769230769230769 0.0280373831775701
GO:CC GO:0000228 nuclear chromosome 0.0362405259774933 252 131 7 0.0534351145038168 0.0277777777777778
GO:CC GO:0043226 organelle 0.044633937390971 14008 40 37 0.925 0.00264134780125642
GO:CC GO:0016607 nuclear speck 0.0454753004702038 412 47 5 0.106382978723404 0.0121359223300971
MIRNA MIRNA:hsa-miR-548a-3p hsa-miR-548a-3p 0.0182871556489373 169 112 8 0.0714285714285714 0.0473372781065089
MIRNA MIRNA:hsa-miR-548g-3p hsa-miR-548g-3p 0.0182871556489373 95 55 5 0.0909090909090909 0.0526315789473684
MIRNA MIRNA:hsa-miR-561-3p hsa-miR-561-3p 0.0182871556489373 140 130 8 0.0615384615384615 0.0571428571428571
MIRNA MIRNA:hsa-miR-204-5p hsa-miR-204-5p 0.0182871556489373 395 13 5 0.384615384615385 0.0126582278481013
MIRNA MIRNA:hsa-miR-30a-5p hsa-miR-30a-5p 0.0209932198216405 730 6 4 0.666666666666667 0.00547945205479452
MIRNA MIRNA:hsa-miR-520f-5p hsa-miR-520f-5p 0.0209932198216405 69 50 4 0.08 0.0579710144927536
MIRNA MIRNA:hsa-miR-5582-3p hsa-miR-5582-3p 0.023009689126493 247 112 9 0.0803571428571429 0.0364372469635627
MIRNA MIRNA:hsa-miR-149-5p hsa-miR-149-5p 0.0246309703644474 394 13 4 0.307692307692308 0.0101522842639594
MIRNA MIRNA:hsa-miR-548e-3p hsa-miR-548e-3p 0.0246309703644474 166 112 7 0.0625 0.0421686746987952
MIRNA MIRNA:hsa-miR-548s hsa-miR-548s 0.0246309703644474 426 13 4 0.307692307692308 0.00938967136150235
MIRNA MIRNA:hsa-miR-367-3p hsa-miR-367-3p 0.0246309703644474 329 62 7 0.112903225806452 0.0212765957446809
MIRNA MIRNA:hsa-miR-548az-3p hsa-miR-548az-3p 0.0246309703644474 166 112 7 0.0625 0.0421686746987952
MIRNA MIRNA:hsa-miR-340-5p hsa-miR-340-5p 0.0246309703644474 340 101 9 0.0891089108910891 0.0264705882352941
MIRNA MIRNA:hsa-miR-363-3p hsa-miR-363-3p 0.0246309703644474 340 62 7 0.112903225806452 0.0205882352941176
MIRNA MIRNA:hsa-miR-548ar-3p hsa-miR-548ar-3p 0.0246309703644474 166 112 7 0.0625 0.0421686746987952
MIRNA MIRNA:hsa-miR-3666 hsa-miR-3666 0.0246309703644474 364 7 3 0.428571428571429 0.00824175824175824
MIRNA MIRNA:hsa-miR-4295 hsa-miR-4295 0.0246309703644474 366 7 3 0.428571428571429 0.00819672131147541
MIRNA MIRNA:hsa-miR-548av-3p hsa-miR-548av-3p 0.0246309703644474 96 94 5 0.0531914893617021 0.0520833333333333
MIRNA MIRNA:hsa-miR-450a-2-3p hsa-miR-450a-2-3p 0.0246309703644474 98 55 4 0.0727272727272727 0.0408163265306122
MIRNA MIRNA:hsa-miR-548f-3p hsa-miR-548f-3p 0.0246309703644474 165 112 7 0.0625 0.0424242424242424
MIRNA MIRNA:hsa-miR-4672 hsa-miR-4672 0.0246309703644474 131 31 4 0.129032258064516 0.0305343511450382
MIRNA MIRNA:hsa-miR-133a-3p hsa-miR-133a-3p 0.0246309703644474 129 14 3 0.214285714285714 0.0232558139534884
MIRNA MIRNA:hsa-miR-23c hsa-miR-23c 0.0246309703644474 131 17 3 0.176470588235294 0.0229007633587786
MIRNA MIRNA:hsa-miR-301b-3p hsa-miR-301b-3p 0.0246309703644474 375 7 3 0.428571428571429 0.008
MIRNA MIRNA:hsa-miR-211-5p hsa-miR-211-5p 0.0246309703644474 332 7 3 0.428571428571429 0.00903614457831325
MIRNA MIRNA:hsa-miR-6884-3p hsa-miR-6884-3p 0.0246309703644474 73 21 3 0.142857142857143 0.0410958904109589
MIRNA MIRNA:hsa-miR-130a-3p hsa-miR-130a-3p 0.0246309703644474 398 13 4 0.307692307692308 0.0100502512562814
MIRNA MIRNA:hsa-miR-454-3p hsa-miR-454-3p 0.0248134712738033 396 7 3 0.428571428571429 0.00757575757575758
MIRNA MIRNA:hsa-miR-301a-3p hsa-miR-301a-3p 0.0248134712738033 395 7 3 0.428571428571429 0.00759493670886076
MIRNA MIRNA:hsa-miR-129-5p hsa-miR-129-5p 0.0248134712738033 621 26 6 0.230769230769231 0.00966183574879227
MIRNA MIRNA:hsa-miR-1202 hsa-miR-1202 0.0249019847768309 58 43 3 0.0697674418604651 0.0517241379310345
MIRNA MIRNA:hsa-miR-22-3p hsa-miR-22-3p 0.025814443220142 163 133 7 0.0526315789473684 0.0429447852760736
MIRNA MIRNA:hsa-miR-588 hsa-miR-588 0.0320692303256817 225 13 3 0.230769230769231 0.0133333333333333
MIRNA MIRNA:hsa-miR-3175 hsa-miR-3175 0.0321997018959523 272 11 3 0.272727272727273 0.0110294117647059
MIRNA MIRNA:hsa-miR-3187-3p hsa-miR-3187-3p 0.0340655295083116 233 13 3 0.230769230769231 0.0128755364806867
MIRNA MIRNA:hsa-miR-4701-5p hsa-miR-4701-5p 0.0369026587205498 245 13 3 0.230769230769231 0.0122448979591837
MIRNA MIRNA:hsa-miR-6768-5p hsa-miR-6768-5p 0.0369026587205498 148 46 4 0.0869565217391304 0.027027027027027
MIRNA MIRNA:hsa-miR-4435 hsa-miR-4435 0.0369026587205498 246 13 3 0.230769230769231 0.0121951219512195
MIRNA MIRNA:hsa-miR-548av-5p hsa-miR-548av-5p 0.0373365242011557 147 22 3 0.136363636363636 0.0204081632653061
MIRNA MIRNA:hsa-miR-26b-5p hsa-miR-26b-5p 0.0373365242011557 1852 84 21 0.25 0.0113390928725702
MIRNA MIRNA:hsa-miR-548k hsa-miR-548k 0.0373365242011557 147 22 3 0.136363636363636 0.0204081632653061
MIRNA MIRNA:hsa-miR-8054 hsa-miR-8054 0.0373365242011557 147 22 3 0.136363636363636 0.0204081632653061
MIRNA MIRNA:hsa-miR-555 hsa-miR-555 0.0408959081026202 56 59 3 0.0508474576271186 0.0535714285714286
MIRNA MIRNA:hsa-miR-6847-5p hsa-miR-6847-5p 0.0415125233208609 162 21 3 0.142857142857143 0.0185185185185185
MIRNA MIRNA:hsa-miR-130b-3p hsa-miR-130b-3p 0.0483207777510046 571 7 3 0.428571428571429 0.00525394045534151
TF TF:M00425_1 Factor: E2F; motif: TTTCGCGC; match class: 1 0.000103730518517946 5355 129 65 0.503875968992248 0.0121381886087768
TF TF:M00427_1 Factor: E2F; motif: TTTSGCGS; match class: 1 0.000267025996178277 3831 132 52 0.393939393939394 0.0135734795092665
TF TF:M04826_1 Factor: p300; motif: ACNTCCG; match class: 1 0.000365256472797448 15260 141 132 0.936170212765957 0.00865006553079948
TF TF:M07250 Factor: E2F-1; motif: NNNSSCGCSAANN 0.000430272874978111 10703 134 101 0.753731343283582 0.00943660655890872
TF TF:M08878_1 Factor: EGR; motif: CGCCCCCGCNN; match class: 1 0.000430272874978111 3224 136 46 0.338235294117647 0.0142679900744417
TF TF:M10119 Factor: REX-1; motif: GGCMGCCATTTT 0.000430272874978111 1888 118 30 0.254237288135593 0.0158898305084746
TF TF:M00516 Factor: E2F-1; motif: TTTSGCGCGMNR 0.000430272874978111 6904 140 78 0.557142857142857 0.011297798377752
TF TF:M08982_1 Factor: YY1; motif: NAANATGGCGNNN; match class: 1 0.000430814479288865 1662 113 27 0.238938053097345 0.0162454873646209
TF TF:M00695 Factor: ETF; motif: GVGGMGG 0.000442457282493099 10430 130 96 0.738461538461539 0.00920421860019175
TF TF:M00427 Factor: E2F; motif: TTTSGCGS 0.000442457282493099 9485 130 90 0.692307692307692 0.00948866631523458
TF TF:M07250_1 Factor: E2F-1; motif: NNNSSCGCSAANN; match class: 1 0.000442457282493099 5515 134 64 0.477611940298507 0.0116047144152312
TF TF:M00738_1 Factor: E2F-4:DP-1; motif: TTTSGCGC; match class: 1 0.000442457282493099 3999 132 51 0.386363636363636 0.0127531882970743
TF TF:M00982 Factor: KROX; motif: CCCGCCCCCRCCCC 0.000442457282493099 7815 136 82 0.602941176470588 0.0104926423544466
TF TF:M07354_1 Factor: Egr-1; motif: GCGGGGGCGG; match class: 1 0.000510700914994658 3561 128 46 0.359375 0.0129177197416456
TF TF:M08205_1 Factor: E2F-1:Elk-1; motif: SGCGCSNNAMCGGAAGT; match class: 1 0.000515728997181201 10438 134 98 0.73134328358209 0.0093887717953631
TF TF:M00333_1 Factor: ZF5; motif: NRNGNGCGCGCWN; match class: 1 0.000557246029176402 12401 136 111 0.816176470588235 0.00895089105717281
TF TF:M03893_1 Factor: WT1; motif: GNGGGGGCGGGG; match class: 1 0.000557246029176402 3980 138 52 0.376811594202899 0.0130653266331658
TF TF:M07615_1 Factor: Sp3; motif: GGGGCGGGGSNN; match class: 1 0.000625966856523338 2885 140 42 0.3 0.0145580589254766
TF TF:M10530 Factor: sp4; motif: NNNGCYCCGCCCCCY 0.000625966856523338 8227 127 79 0.622047244094488 0.00960252826060532
TF TF:M00695_1 Factor: ETF; motif: GVGGMGG; match class: 1 0.000625966856523338 7032 90 54 0.6 0.00767918088737201
TF TF:M03893 Factor: WT1; motif: GNGGGGGCGGGG 0.000625966856523338 8290 141 87 0.617021276595745 0.0104945717732207
TF TF:M12273_1 Factor: YY1; motif: GGCSGCCATTTTGN; match class: 1 0.000625966856523338 1261 113 22 0.194690265486726 0.0174464710547185
TF TF:M00982_1 Factor: KROX; motif: CCCGCCCCCRCCCC; match class: 1 0.000625966856523338 3518 136 47 0.345588235294118 0.0133598635588402
TF TF:M10068 Factor: Sox-3; motif: NCCTTTGTNYN 0.000625966856523338 1650 129 28 0.217054263565891 0.016969696969697
TF TF:M09723 Factor: BTEB1; motif: GGGGGCGGGGCNGSGGGNGS 0.000625966856523338 10156 125 90 0.72 0.00886175659708547
TF TF:M00740_1 Factor: Rb:E2F-1:DP-1; motif: TTTSGCGC; match class: 1 0.000723700032884356 4583 140 57 0.407142857142857 0.0124372681649575
TF TF:M01308 Factor: Sox-4; motif: AACAAWGR 0.000740627515996457 1653 138 29 0.210144927536232 0.0175438596491228
TF TF:M01035_1 Factor: YY1; motif: NYNKCCATNTT; match class: 1 0.000939680725218004 1112 122 21 0.172131147540984 0.0188848920863309
TF TF:M08878 Factor: EGR; motif: CGCCCCCGCNN 0.000939680725218004 7483 141 80 0.567375886524823 0.0106908993719097
TF TF:M00430_1 Factor: E2F-1; motif: NTTSGCGG; match class: 1 0.000939680725218004 2524 125 35 0.28 0.0138668779714739
TF TF:M08205 Factor: E2F-1:Elk-1; motif: SGCGCSNNAMCGGAAGT 0.0010156884704858 14429 136 121 0.889705882352941 0.00838588952803382
TF TF:M01240_1 Factor: BEN; motif: CAGCGRNV; match class: 1 0.00108439749294969 13227 125 106 0.848 0.00801391093974446
TF TF:M01873 Factor: Egr-1; motif: GCGGGGGCGG 0.00108439749294969 6738 141 74 0.524822695035461 0.0109824873849807
TF TF:M02036 Factor: WT1; motif: CGCCCCCNCN 0.00110612800828835 9767 141 96 0.680851063829787 0.0098290160745367
TF TF:M07617 Factor: Sp4; motif: SCCCCKCCCCCSN 0.00112920552583559 3595 138 47 0.340579710144928 0.0130737134909597
TF TF:M09636_1 Factor: MAZ; motif: GGGMGGGGSSGGGGGGGGGGGG; match class: 1 0.00112920552583559 14096 141 123 0.872340425531915 0.00872587968217934
TF TF:M12351_1 Factor: TIEG1; motif: NCCCNSNCCCCGCCCCC; match class: 1 0.00113869196445926 8180 126 77 0.611111111111111 0.00941320293398533
TF TF:M09894_1 Factor: E2F-4; motif: SNGGGCGGGAANN; match class: 1 0.00113914942737091 13929 141 122 0.865248226950355 0.00875870486036327
TF TF:M00428 Factor: E2F-1; motif: NKTSSCGC 0.00120020023740866 8947 141 90 0.638297872340426 0.0100592377333184
TF TF:M00425 Factor: E2F; motif: TTTCGCGC 0.00124448199489035 11043 130 97 0.746153846153846 0.00878384496966404
TF TF:M00740 Factor: Rb:E2F-1:DP-1; motif: TTTSGCGC 0.00124448199489035 10427 136 97 0.713235294117647 0.00930277165052268
TF TF:M01219 Factor: SP1:SP3; motif: CCSCCCCCYCC 0.00132585976803989 6812 141 74 0.524822695035461 0.0108631826189078
TF TF:M00940 Factor: E2F-1; motif: NTTTCGCGCS 0.00134731483595873 7802 136 79 0.580882352941177 0.0101256088182517
TF TF:M07208 Factor: EGR1; motif: NCNCCGCCCCCGCN 0.00137539930093359 6183 136 67 0.492647058823529 0.0108361636745916
TF TF:M00050 Factor: E2F; motif: TTTSGCGC 0.00144268624260634 7056 135 73 0.540740740740741 0.0103458049886621
TF TF:M12156 Factor: Sp2; motif: NTAAGYCCCGCCCMCTN 0.00146251761391557 4320 136 52 0.382352941176471 0.012037037037037
TF TF:M03567_1 Factor: Sp2; motif: NYSGCCCCGCCCCCY; match class: 1 0.00146251761391557 3614 140 47 0.335714285714286 0.0130049806308799
TF TF:M04287_1 Factor: BARHL2; motif: NNTAAAYGNN; match class: 1 0.00146251761391557 713 139 17 0.122302158273381 0.0238429172510519
TF TF:M00986 Factor: Churchill; motif: CGGGNN 0.00146251761391557 14197 136 119 0.875 0.0083820525463126
TF TF:M12158 Factor: KLF15; motif: NCCMCGCCCMCN 0.00146251761391557 11088 112 85 0.758928571428571 0.00766594516594517
TF TF:M00933 Factor: Sp1; motif: CCCCGCCCCN 0.00146271200694133 9715 126 86 0.682539682539683 0.00885229027277406
TF TF:M07226 Factor: SP1; motif: NCCCCKCCCCC 0.00146271200694133 8292 126 77 0.611111111111111 0.00928605885190545
TF TF:M12155 Factor: Sp2; motif: NTWAGTCCCGCCCMCTT 0.0015777678037978 4591 136 54 0.397058823529412 0.0117621433238946
TF TF:M00932 Factor: Sp1; motif: NNGGGGCGGGGNN 0.00163607925180824 10419 134 95 0.708955223880597 0.00911795757750264
TF TF:M00196 Factor: Sp1; motif: NGGGGGCGGGGYN 0.00163607925180824 10233 136 95 0.698529411764706 0.0092836900224763
TF TF:M11639_1 Factor: Sox-4; motif: NAACAAAGRN; match class: 1 0.00163607925180824 347 46 7 0.152173913043478 0.0201729106628242
TF TF:M07397 Factor: ZBP89; motif: CCCCKCCCCCNN 0.00175646646771438 7143 126 69 0.547619047619048 0.00965980680386392
TF TF:M07409 Factor: BTEB2; motif: GCCCCRCCCH 0.00175923185373746 5198 140 60 0.428571428571429 0.0115429011158138
TF TF:M08874 Factor: E2F1; motif: NNNNNGCGSSAAAN 0.00175923185373746 7201 97 56 0.577319587628866 0.00777669768087766
TF TF:M02036_1 Factor: WT1; motif: CGCCCCCNCN; match class: 1 0.00176217614365142 5290 138 60 0.434782608695652 0.0113421550094518
TF TF:M00426_1 Factor: E2F; motif: TTTSGCGS; match class: 1 0.00176217614365142 5830 132 62 0.46969696969697 0.0106346483704974
TF TF:M00738 Factor: E2F-4:DP-1; motif: TTTSGCGC 0.00176217614365142 9812 136 92 0.676470588235294 0.00937627395026498
TF TF:M09970 Factor: KLF3; motif: NNNNNNGGGCGGGGCNNGN 0.00178290388351385 7728 112 66 0.589285714285714 0.00854037267080745
TF TF:M10086 Factor: TAFII250; motif: RARRWGGCGGMGGNGR 0.00183325835008261 9262 141 91 0.645390070921986 0.00982509177283524
TF TF:M11381_1 Factor: ESE-1; motif: SATKGCGGATGCN; match class: 1 0.00186156943680584 9745 137 92 0.671532846715328 0.00944073884043099
TF TF:M00430 Factor: E2F-1; motif: NTTSGCGG 0.00188725053603423 8016 133 78 0.586466165413534 0.00973053892215569
TF TF:M10438_1 Factor: ZF5; motif: GGSGCGCGS; match class: 1 0.00188725053603423 14873 136 122 0.897058823529412 0.00820278356753849
TF TF:M00431 Factor: E2F-1; motif: TTTSGCGS 0.00189017564726271 7257 136 74 0.544117647058823 0.0101970511230536
TF TF:M00243 Factor: Egr-1; motif: WTGCGTGGGCGK 0.00194503006622328 5356 126 56 0.444444444444444 0.0104555638536221
TF TF:M02281 Factor: SP1; motif: CCCCKCCCCC 0.00194503006622328 6480 138 69 0.5 0.0106481481481481
TF TF:M07302 Factor: NF-Y; motif: RGCCAATCRGN 0.00194503006622328 1576 135 26 0.192592592592593 0.016497461928934
TF TF:M11578 Factor: foxl2; motif: NACGTMAACAN 0.00245332581654534 5451 63 33 0.523809523809524 0.00605393505778756
TF TF:M09826 Factor: BTEB3; motif: CCNNSCCNSCCCCKCCCCC 0.00245332581654534 11467 130 98 0.753846153846154 0.00854626319002355
TF TF:M02106 Factor: NF-YA; motif: CRGCCAATCAGNRN 0.00245332581654534 1741 90 21 0.233333333333333 0.0120620333141872
TF TF:M07206 Factor: E2F-1; motif: NGGGCGGGARV 0.00259094457399338 14575 136 120 0.882352941176471 0.00823327615780446
TF TF:M09636 Factor: MAZ; motif: GGGMGGGGSSGGGGGGGGGGGG 0.00259094457399338 16244 130 123 0.946153846153846 0.00757202659443487
TF TF:M12160 Factor: KLF15; motif: RCCMCRCCCMCN 0.00260323697808181 12729 112 92 0.821428571428571 0.00722759054128368
TF TF:M12275_1 Factor: YY1; motif: NGCCGCCATYTTGN; match class: 1 0.00262173221583475 1600 113 23 0.20353982300885 0.014375
TF TF:M10436_1 Factor: YY1; motif: CAANATGGCGGC; match class: 1 0.00288501195792498 2285 115 29 0.252173913043478 0.012691466083151
TF TF:M03814 Factor: BTEB2; motif: GNAGGGGGNGGGSSNN 0.00288501195792498 5124 130 55 0.423076923076923 0.0107338017174083
TF TF:M12159 Factor: KLF15; motif: GCCACGCCCMCN 0.00292649970135619 1422 136 24 0.176470588235294 0.0168776371308017
TF TF:M12310 Factor: ZNF597; motif: NGCCGCCATTTTGN 0.00302646622033978 437 112 11 0.0982142857142857 0.0251716247139588
TF TF:M01873_1 Factor: Egr-1; motif: GCGGGGGCGG; match class: 1 0.00318127621417943 2672 136 36 0.264705882352941 0.0134730538922156
TF TF:M07397_1 Factor: ZBP89; motif: CCCCKCCCCCNN; match class: 1 0.00318127621417943 2951 138 39 0.282608695652174 0.013215859030837
TF TF:M08441_1 Factor: AP-2gamma:Elk-1; motif: NGCCKNRGGSGRCGGAAGTG; match class: 1 0.00318127621417943 12761 141 113 0.801418439716312 0.00885510539926338
TF TF:M08525_1 Factor: E2F-1:HES-7; motif: GGCRCGTGSYNNWNGGCGCSM; match class: 1 0.00318127621417943 15268 125 114 0.912 0.0074665968037726
TF TF:M00940_1 Factor: E2F-1; motif: NTTTCGCGCS; match class: 1 0.00318127621417943 2643 132 35 0.265151515151515 0.0132425274309497
TF TF:M11531 Factor: E2F-2; motif: GCGCGCGCGYW 0.00318127621417943 13270 96 82 0.854166666666667 0.00617935192162773
TF TF:M01284 Factor: Sox-9; motif: RNACAAAGGVN 0.00318127621417943 5964 130 61 0.469230769230769 0.0102280348759222
TF TF:M05439_1 Factor: RREB-1; motif: GGGWCSA; match class: 1 0.00329216799841593 3200 133 40 0.300751879699248 0.0125
TF TF:M07129 Factor: Sp2; motif: GYCCCGCCYCYNNNN 0.00334821527241968 6260 140 67 0.478571428571429 0.010702875399361
TF TF:M07405_1 Factor: SREBP-1; motif: RTCACCCCAY; match class: 1 0.00352713856514573 1516 42 12 0.285714285714286 0.0079155672823219
TF TF:M10072 Factor: sp4; motif: NNGNARGRGGCGGRGCNNRR 0.00356870101516502 10494 136 95 0.698529411764706 0.00905279207166
TF TF:M07354 Factor: Egr-1; motif: GCGGGGGCGG 0.00356870101516502 7801 141 79 0.560283687943262 0.0101269068068196
TF TF:M10530_1 Factor: sp4; motif: NNNGCYCCGCCCCCY; match class: 1 0.00360178230171744 3780 138 46 0.333333333333333 0.0121693121693122
TF TF:M01100_1 Factor: LRF; motif: GGGGKYNNB; match class: 1 0.00360178230171744 2762 123 34 0.276422764227642 0.0123099203475742
TF TF:M09723_1 Factor: BTEB1; motif: GGGGGCGGGGCNGSGGGNGS; match class: 1 0.0037230206312758 6113 141 66 0.468085106382979 0.0107966628496646
TF TF:M00775 Factor: NF-Y; motif: NNNNRRCCAATSR 0.00375866034997705 1428 89 18 0.202247191011236 0.0126050420168067
TF TF:M02106_1 Factor: NF-YA; motif: CRGCCAATCAGNRN; match class: 1 0.00386971356065339 217 90 7 0.0777777777777778 0.032258064516129
TF TF:M07226_1 Factor: SP1; motif: NCCCCKCCCCC; match class: 1 0.00386971356065339 3915 138 47 0.340579710144928 0.0120051085568327
TF TF:M03896 Factor: EGR1; motif: NACGCCCACGCANW 0.00410781118582671 6129 136 64 0.470588235294118 0.0104421602218959
TF TF:M00716 Factor: ZF5; motif: GSGCGCGR 0.00435963211382735 16103 136 127 0.933823529411765 0.00788672918089797
TF TF:M10104_1 Factor: YY1; motif: CAARATGGCGGC; match class: 1 0.00435963211382735 1138 122 19 0.155737704918033 0.0166959578207381
TF TF:M07615 Factor: Sp3; motif: GGGGCGGGGSNN 0.00439865348491706 6807 122 63 0.516393442622951 0.00925517849272807
TF TF:M00919 Factor: E2F; motif: NCSCGCSAAAN 0.0044017854394051 6149 136 64 0.470588235294118 0.0104081964547081
TF TF:M00932_1 Factor: Sp1; motif: NNGGGGCGGGGNN; match class: 1 0.00476872526020736 6047 141 65 0.460992907801418 0.010749131800893
TF TF:M09967 Factor: AP-2rep; motif: NGGGGCGGGGC 0.00505299496340123 4023 140 48 0.342857142857143 0.0119313944817301
TF TF:M00246 Factor: Egr-2; motif: NTGCGTRGGCGK 0.00505299496340123 6212 115 56 0.48695652173913 0.00901481004507405
TF TF:M01219_1 Factor: SP1:SP3; motif: CCSCCCCCYCC; match class: 1 0.00511237281591936 2937 138 38 0.27536231884058 0.0129383724889343
TF TF:M07395 Factor: Sp1; motif: NGGGGCGGGGN 0.00512587679504158 10640 134 94 0.701492537313433 0.00883458646616541
TF TF:M01035 Factor: YY1; motif: NYNKCCATNTT 0.00528115803553361 5924 89 44 0.49438202247191 0.00742741390952059
TF TF:M00426 Factor: E2F; motif: TTTSGCGS 0.00528115803553361 11885 130 99 0.761538461538461 0.0083298275136727
TF TF:M04953 Factor: Sp1; motif: GGNDGGRGGCGGGG 0.00528115803553361 8688 134 81 0.604477611940298 0.0093232044198895
TF TF:M01168_1 Factor: SREBP; motif: NNNNYCACNCCANNN; match class: 1 0.00548115986291407 1367 42 11 0.261904761904762 0.00804681784930505
TF TF:M12313 Factor: ZNF460; motif: NNACNCCCCCCNN 0.00557686320915562 5825 125 57 0.456 0.00978540772532189
TF TF:M01273 Factor: SP4; motif: SCCCCGCCCCS 0.00557686320915562 3296 138 41 0.297101449275362 0.0124393203883495
TF TF:M10578_1 Factor: Barhl-1; motif: NTAAACGN; match class: 1 0.00582833503857964 1391 139 23 0.165467625899281 0.0165348670021567
TF TF:M07234_1 Factor: YY1; motif: CAARATGGCNGC; match class: 1 0.00587892254622067 1177 122 19 0.155737704918033 0.016142735768904
TF TF:M08899 Factor: SOX; motif: NNNNCWTTGTT 0.00587892254622067 2066 102 24 0.235294117647059 0.0116166505324298
TF TF:M00918 Factor: E2F; motif: TTTSGCGSG 0.00588971657842256 5575 136 59 0.433823529411765 0.0105829596412556
TF TF:M10435_1 Factor: Sp2; motif: GGGGCGGGG; match class: 1 0.00609391964434246 3495 140 43 0.307142857142857 0.0123032904148784
TF TF:M10069_1 Factor: Sox-4; motif: NYCTTTGTYYYN; match class: 1 0.00609391964434246 1742 46 13 0.282608695652174 0.00746268656716418
TF TF:M09834_1 Factor: ZNF148; motif: NNNNNNCCNNCCCCTCCCCCACCCN; match class: 1 0.00609391964434246 2869 138 37 0.268115942028986 0.0128964796096201
TF TF:M00986_1 Factor: Churchill; motif: CGGGNN; match class: 1 0.00609391964434246 10357 136 93 0.683823529411765 0.0089794341990924
TF TF:M00516_1 Factor: E2F-1; motif: TTTSGCGCGMNR; match class: 1 0.00609391964434246 2069 115 26 0.226086956521739 0.0125664572257129
TF TF:M07063_1 Factor: Sp1; motif: GGGGCGGGGC; match class: 1 0.00609391964434246 3495 140 43 0.307142857142857 0.0123032904148784
TF TF:M03862_1 Factor: YB-1; motif: NNNNCCAATNN; match class: 1 0.00613691753697226 3120 137 39 0.284671532846715 0.0125
TF TF:M12173_1 Factor: GKLF; motif: NNCCMCRCCCN; match class: 1 0.00646338422045657 4965 136 54 0.397058823529412 0.0108761329305136
TF TF:M02044_1 Factor: YY1; motif: GCCGCCATTTTG; match class: 1 0.0068312824720892 1198 122 19 0.155737704918033 0.0158597662771285
TF TF:M09819_1 Factor: SOX10; motif: NNAACAAAGNN; match class: 1 0.0069139747810174 1114 131 19 0.145038167938931 0.0170556552962298
TF TF:M00024_1 Factor: E2F-1; motif: TWSGCGCGAAAAYKR; match class: 1 0.00693295563498017 2681 127 33 0.259842519685039 0.0123088399850802
TF TF:M09826_1 Factor: BTEB3; motif: CCNNSCCNSCCCCKCCCCC; match class: 1 0.00704345323063224 7508 125 68 0.544 0.00905700586041556
TF TF:M00428_1 Factor: E2F-1; motif: NKTSSCGC; match class: 1 0.0070916658317724 3615 141 44 0.312056737588652 0.0121715076071923
TF TF:M05444 Factor: CPBP; motif: NGGGCGG 0.00731389951542656 8578 135 80 0.592592592592593 0.00932618325950105
TF TF:M05332 Factor: Sp2; motif: WGGGCGG 0.00731389951542656 8578 135 80 0.592592592592593 0.00932618325950105
TF TF:M05361 Factor: Sp6; motif: WGGGCGG 0.00731389951542656 8578 135 80 0.592592592592593 0.00932618325950105
TF TF:M04953_1 Factor: Sp1; motif: GGNDGGRGGCGGGG; match class: 1 0.00731389951542656 4065 138 47 0.340579710144928 0.0115621156211562
TF TF:M00939 Factor: E2F; motif: TTTSGCGSG 0.00735823275252893 6433 136 65 0.477941176470588 0.0101041504741178
TF TF:M04691 Factor: Kaiso; motif: TCTCGCGAG 0.00740034301222053 15113 131 117 0.893129770992366 0.00774167934890492
TF TF:M08390_1 Factor: A-Myb:Elf-1; motif: NMCCGGAACCGTTA; match class: 1 0.00761176051145819 4784 55 26 0.472727272727273 0.00543478260869565
TF TF:M03807_1 Factor: SP2; motif: GNNGGGGGCGGGGSN; match class: 1 0.0077148402069841 4199 138 48 0.347826086956522 0.0114312931650393
TF TF:M09970_1 Factor: KLF3; motif: NNNNNNGGGCGGGGCNNGN; match class: 1 0.00774686031898284 3783 140 45 0.321428571428571 0.0118953211736717
TF TF:M11535 Factor: E2F-4; motif: TTTTGGCGCCAWWN 0.00777140512454518 10884 141 99 0.702127659574468 0.00909592061742007
TF TF:M07380_1 Factor: E2F-4; motif: NTTTCSCGCC; match class: 1 0.00791501387898325 7965 136 76 0.558823529411765 0.00954174513496547
TF TF:M12157 Factor: KLF15; motif: RCCACGCCCCCC 0.00818374774868253 3619 138 43 0.311594202898551 0.0118817352859906
TF TF:M11531_1 Factor: E2F-2; motif: GCGCGCGCGYW; match class: 1 0.00833690651808436 12351 136 105 0.772058823529412 0.00850133592421666
TF TF:M11603 Factor: TCF-1; motif: ACATCGRGRCGCTGW 0.00864558007161267 16361 130 122 0.938461538461538 0.00745675692194854
TF TF:M11535_1 Factor: E2F-4; motif: TTTTGGCGCCAWWN; match class: 1 0.00864558007161267 6532 140 67 0.478571428571429 0.010257195345989
TF TF:M10785 Factor: hoxa9; motif: RTCGTWANNN 0.00868668415359266 5632 126 55 0.436507936507937 0.009765625
TF TF:M03925_1 Factor: YY2; motif: NCCGCCATNTY; match class: 1 0.00868668415359266 765 133 15 0.112781954887218 0.0196078431372549
TF TF:M12351 Factor: TIEG1; motif: NCCCNSNCCCCGCCCCC 0.00869885497769887 12302 128 99 0.7734375 0.00804747195577955
TF TF:M10121 Factor: ZFX; motif: SNAGGCCNCR 0.00869885497769887 3997 134 45 0.335820895522388 0.0112584438328747
TF TF:M09765 Factor: SP1; motif: NRGKGGGCGGGGCN 0.00877361696929715 7469 140 74 0.528571428571429 0.00990761815504084
TF TF:M07039 Factor: ETF; motif: CCCCGCCCCYN 0.00884299179386799 16384 112 106 0.946428571428571 0.0064697265625
TF TF:M07436_1 Factor: WT1; motif: NNGGGNGGGSGN; match class: 1 0.00927830596692792 2405 138 32 0.231884057971014 0.0133056133056133
TF TF:M12151 Factor: Sp1; motif: NWRGCCMCGCCCMCN 0.00935155779970493 6821 140 69 0.492857142857143 0.0101158187948981
TF TF:M11438 Factor: SAP-1; motif: NTCGTAAATGCN 0.00935155779970493 5901 124 56 0.451612903225806 0.00948991696322657
TF TF:M00716_1 Factor: ZF5; motif: GSGCGCGR; match class: 1 0.00989792413035374 14106 141 119 0.843971631205674 0.00843612647100525
TF TF:M11601_1 Factor: TCF-1; motif: ACATCGRGRCGCTGW; match class: 1 0.00989792413035374 11053 129 92 0.713178294573643 0.00832353207274043
TF TF:M10005_1 Factor: NF-YA; motif: NYRRCCAATCAGAR; match class: 1 0.00989792413035374 277 117 8 0.0683760683760684 0.0288808664259928
TF TF:M11221_1 Factor: CREB1; motif: RTGACGYGTCAN; match class: 1 0.0100405464816542 5695 134 58 0.432835820895522 0.0101843722563652
TF TF:M09658 Factor: Sp2; motif: GGSNNGGGGGCGGGGCCNGNGS 0.0101145344069313 5262 138 56 0.405797101449275 0.0106423413150893
TF TF:M10849_1 Factor: Cdx-2; motif: NRTCGTAANNNN; match class: 1 0.0101145344069313 4497 75 31 0.413333333333333 0.00689348454525239
TF TF:M07206_1 Factor: E2F-1; motif: NGGGCGGGARV; match class: 1 0.0104661218500316 10849 136 95 0.698529411764706 0.00875656742556918
TF TF:M04107 Factor: RUNX2; motif: WRACCGCANWAACCGCAN 0.0104910343234582 12351 141 108 0.765957446808511 0.00874423123633714
TF TF:M10885 Factor: PRX-2; motif: NKCGTTAN 0.0107053434263458 5715 134 58 0.432835820895522 0.0101487314085739
TF TF:M10887 Factor: PRX-2; motif: NNCRTTAN 0.0107053434263458 5715 134 58 0.432835820895522 0.0101487314085739
TF TF:M11529_1 Factor: E2F-2; motif: GCGCGCGCNCS; match class: 1 0.0107171651817062 14473 141 121 0.858156028368794 0.00836039521868306
TF TF:M00931 Factor: Sp1; motif: GGGGCGGGGC 0.0107171651817062 10281 134 90 0.671641791044776 0.00875401225561716
TF TF:M04696_1 Factor: YY1; motif: GCCGCCATNTTGNNNNNGGNCN; match class: 1 0.0107805899674218 1973 113 24 0.212389380530973 0.0121642169285352
TF TF:M04110 Factor: RUNX3; motif: NRACCGCANWAACCRCAN 0.0109605383343985 9266 141 87 0.617021276595745 0.00938916468810706
TF TF:M00245_1 Factor: Egr-3; motif: NTGCGTGGGCGK; match class: 1 0.0109605383343985 2363 90 23 0.255555555555556 0.00973338975878121
TF TF:M10632 Factor: Nkx2-8; motif: STCGTTGAN 0.0109605383343985 4871 50 24 0.48 0.00492711968794909
TF TF:M10112 Factor: Miz-1; motif: NNRGGWGGGGGAGGGGMRR 0.0109799892990313 8711 141 83 0.588652482269504 0.00952818275743313
TF TF:M10072_1 Factor: sp4; motif: NNGNARGRGGCGGRGCNNRR; match class: 1 0.0109799892990313 6225 140 64 0.457142857142857 0.010281124497992
TF TF:M08487 Factor: GCMa:Erg; motif: ATGCGGGCGGAARKG 0.0109799892990313 13942 140 117 0.835714285714286 0.00839190933868885
TF TF:M10006 Factor: NF-YC; motif: NNRRCCAATCAGNR 0.0111569235192416 2510 118 29 0.245762711864407 0.0115537848605578
TF TF:M04515 Factor: E2F-1; motif: WWTGGCGCCAAA 0.0111569235192416 13334 141 114 0.808510638297872 0.00854957252137393
TF TF:M02089 Factor: E2F-3; motif: GGCGGGN 0.0111569235192416 13173 141 113 0.801418439716312 0.0085781522811812
TF TF:M02281_1 Factor: SP1; motif: CCCCKCCCCC; match class: 1 0.0111569235192416 2558 138 33 0.239130434782609 0.0129007036747459
TF TF:M08461 Factor: Erm:EVX1; motif: NNCGGAAATKR 0.0112789066709979 3396 28 13 0.464285714285714 0.00382803297997644
TF TF:M03928 Factor: ZBTB7B; motif: NCGACCACCGAA 0.0114452976022449 633 132 13 0.0984848484848485 0.0205371248025276
TF TF:M10026 Factor: PATZ; motif: GGGGNGGGGGMKGGRRNGGNRN 0.0118391873708082 8389 126 73 0.579365079365079 0.00870187149839075
TF TF:M07614 Factor: Sox-4; motif: ACAAWGNRNYN 0.0118795200204697 1860 60 15 0.25 0.00806451612903226
TF TF:M07614_1 Factor: Sox-4; motif: ACAAWGNRNYN; match class: 1 0.0118795200204697 119 23 3 0.130434782608696 0.0252100840336134
TF TF:M10999 Factor: LIM-1; motif: NNCGTTAN 0.0119434052702666 5894 134 59 0.440298507462687 0.0100101798439091
TF TF:M02044 Factor: YY1; motif: GCCGCCATTTTG 0.0119804455726107 6102 122 56 0.459016393442623 0.00917731891183219
TF TF:M00803 Factor: E2F; motif: GGCGSG 0.0119937167858094 13190 90 75 0.833333333333333 0.00568612585291888
TF TF:M00244 Factor: NGFI-C; motif: WTGCGTGGGYGG 0.0119937167858094 6184 118 55 0.466101694915254 0.00889391979301423
TF TF:M07409_1 Factor: BTEB2; motif: GCCCCRCCCH; match class: 1 0.0120213299312664 1829 138 26 0.188405797101449 0.014215418261345
TF TF:M09892 Factor: E2F-1; motif: NNNNGGCGGGAARN 0.0120213299312664 13528 141 115 0.815602836879433 0.00850088704908338
TF TF:M00287 Factor: NF-Y; motif: NNNRRCCAATSRGNNN 0.0121011421203322 1635 90 18 0.2 0.0110091743119266
TF TF:M02071 Factor: ETV7; motif: NCCGGAANNN 0.0121974697514535 10116 140 92 0.657142857142857 0.00909450375642546
TF TF:M11395 Factor: Erg; motif: NACCGGAWWTCCGGTN 0.0121974697514535 8715 128 76 0.59375 0.0087205966724039
TF TF:M00333 Factor: ZF5; motif: NRNGNGCGCGCWN 0.0121974697514535 15072 136 120 0.882352941176471 0.00796178343949045
TF TF:M02065 Factor: ER81; motif: RCCGGAARYN 0.0124926230934024 12550 130 101 0.776923076923077 0.00804780876494024
TF TF:M04516 Factor: E2F-1; motif: TTTGGCGCCAAA 0.0125011306938809 11383 130 94 0.723076923076923 0.00825792848985329
TF TF:M01303_1 Factor: SP1; motif: GGGGYGGGGNS; match class: 1 0.0127042130577903 3507 138 41 0.297101449275362 0.0116909039064728
TF TF:M01240 Factor: BEN; motif: CAGCGRNV 0.0128841270798598 16498 130 122 0.938461538461538 0.00739483573766517
TF TF:M03920 Factor: SP1; motif: RCCMCRCCCMC 0.0128841270798598 7283 141 72 0.51063829787234 0.00988603597418646
TF TF:M08899_1 Factor: SOX; motif: NNNNCWTTGTT; match class: 1 0.0129949261283588 154 45 4 0.0888888888888889 0.025974025974026
TF TF:M08423 Factor: TEF-3:ER81; motif: ACCGGAAATRCC 0.0129949261283588 3845 32 15 0.46875 0.00390117035110533
TF TF:M08390 Factor: A-Myb:Elf-1; motif: NMCCGGAACCGTTA 0.0130336994191803 11072 91 67 0.736263736263736 0.00605130057803468
TF TF:M07380 Factor: E2F-4; motif: NTTTCSCGCC 0.0130776867156601 13022 136 108 0.794117647058823 0.0082936568883428
TF TF:M02065_1 Factor: ER81; motif: RCCGGAARYN; match class: 1 0.0130944303766739 6749 117 58 0.495726495726496 0.00859386575789006
TF TF:M07063 Factor: Sp1; motif: GGGGCGGGGC 0.0130944303766739 7696 141 75 0.531914893617021 0.00974532224532225
TF TF:M05444_1 Factor: CPBP; motif: NGGGCGG; match class: 1 0.0130944303766739 3313 128 37 0.2890625 0.0111681255659523
TF TF:M10435 Factor: Sp2; motif: GGGGCGGGG 0.0130944303766739 7696 141 75 0.531914893617021 0.00974532224532225
TF TF:M05361_1 Factor: Sp6; motif: WGGGCGG; match class: 1 0.0130944303766739 3313 128 37 0.2890625 0.0111681255659523
TF TF:M05332_1 Factor: Sp2; motif: WGGGCGG; match class: 1 0.0130944303766739 3313 128 37 0.2890625 0.0111681255659523
TF TF:M10783 Factor: hoxa9; motif: RTCGTWAANN 0.0132149901706545 1897 31 10 0.32258064516129 0.00527148128624143
TF TF:M03924 Factor: YY1; motif: NNCGCCATTNN 0.0133650860113553 10084 134 88 0.656716417910448 0.00872669575565252
TF TF:M00196_1 Factor: Sp1; motif: NGGGGGCGGGGYN; match class: 1 0.0133650860113553 5919 140 61 0.435714285714286 0.0103057948977868
TF TF:M03970 Factor: ELK1; motif: ACCGGAAGTN 0.013520241046375 4782 52 24 0.461538461538462 0.00501882057716437
TF TF:M10086_1 Factor: TAFII250; motif: RARRWGGCGGMGGNGR; match class: 1 0.0135332707362595 4153 141 47 0.333333333333333 0.0113171201541055
TF TF:M00933_1 Factor: Sp1; motif: CCCCGCCCCN; match class: 1 0.0135509748947241 5166 140 55 0.392857142857143 0.0106465350367789
TF TF:M00025 Factor: Elk-1; motif: NNNNCCGGAARTNN 0.0137364417689442 10262 117 79 0.675213675213675 0.00769830442408887
TF TF:M00803_1 Factor: E2F; motif: GGCGSG; match class: 1 0.0142561572994561 10230 136 90 0.661764705882353 0.00879765395894428
TF TF:M03807 Factor: SP2; motif: GNNGGGGGCGGGGSN 0.0147257810923646 8415 141 80 0.567375886524823 0.0095068330362448
TF TF:M10006_1 Factor: NF-YC; motif: NNRRCCAATCAGNR; match class: 1 0.0147257810923646 388 117 9 0.0769230769230769 0.0231958762886598
TF TF:M00077 Factor: GATA-3; motif: NNGATARNG 0.0149759291358843 1447 21 7 0.333333333333333 0.00483759502418798
TF TF:M04823 Factor: E2F-4; motif: NNTTCCCGCCNN 0.0151037520237182 12747 136 106 0.779411764705882 0.00831568212128344
TF TF:M03989_1 Factor: FLI1; motif: ACCGGAAATCCGGT; match class: 1 0.0153020364010936 5595 128 54 0.421875 0.0096514745308311
TF TF:M03989 Factor: FLI1; motif: ACCGGAAATCCGGT 0.0158193646580628 10442 129 87 0.674418604651163 0.00833173721509289
TF TF:M00793 Factor: YY1; motif: GCCATNTTN 0.0159428496798452 5186 89 38 0.426966292134831 0.00732741997686078
TF TF:M07268 Factor: Sox-4; motif: BCWTTGT 0.0164108808473472 5575 54 27 0.5 0.00484304932735426
TF TF:M00024 Factor: E2F-1; motif: TWSGCGCGAAAAYKR 0.0165096175082402 8919 123 74 0.601626016260163 0.00829689427065815
TF TF:M09816 Factor: NFYA; motif: RRCCAATCAGN 0.0165979801902793 1969 42 12 0.285714285714286 0.00609446419502285
TF TF:M01104_1 Factor: MOVO-B; motif: GNGGGGG; match class: 1 0.0165979801902793 5626 125 53 0.424 0.00942054745822965
TF TF:M09973_1 Factor: CPBP; motif: GNNRGGGHGGGGNNGGGRN; match class: 1 0.0165979801902793 6607 138 65 0.471014492753623 0.00983805055244438
TF TF:M12158_1 Factor: KLF15; motif: NCCMCGCCCMCN; match class: 1 0.0165979801902793 6004 126 56 0.444444444444444 0.00932711525649567
TF TF:M11638_1 Factor: Sox-4; motif: NAACAAAGRN; match class: 1 0.0165979801902793 296 46 5 0.108695652173913 0.0168918918918919
TF TF:M11018_1 Factor: IRX-1; motif: NACRYNNNNNNNNRYGNN; match class: 1 0.0165979801902793 15920 136 124 0.911764705882353 0.00778894472361809
TF TF:M09898 Factor: Egr-2; motif: GNGRRNGWGKGGGNGGRG 0.0171498415527974 6484 138 64 0.463768115942029 0.00987045033929673
TF TF:M11603_1 Factor: TCF-1; motif: ACATCGRGRCGCTGW; match class: 1 0.0171498415527974 13184 130 104 0.8 0.00788834951456311
TF TF:M10151_1 Factor: EZI; motif: GGGGAGGGGRRGGRGRRGGRRR; match class: 1 0.0171498415527974 575 136 12 0.0882352941176471 0.0208695652173913
TF TF:M10426 Factor: ctcf; motif: CCRSCAGGGGGCGCN 0.0172256554659733 9305 141 86 0.609929078014184 0.0092423428264374
TF TF:M00931_1 Factor: Sp1; motif: GGGGCGGGGC; match class: 1 0.0172256554659733 5905 101 46 0.455445544554455 0.00779000846740051
TF TF:M00687 Factor: alpha-CP1; motif: CAGCCAATGAG 0.0172256554659733 2326 126 28 0.222222222222222 0.0120378331900258
TF TF:M00736 Factor: E2F-1:DP-1; motif: TTTCSCGC 0.0173584692009153 10390 135 90 0.666666666666667 0.00866217516843118
TF TF:M08526_1 Factor: E2F-3:HES-7; motif: NNNSGCGCSNNNNNCRCGYGNN; match class: 1 0.017380246670391 14997 141 123 0.872340425531915 0.00820164032806561
TF TF:M00245 Factor: Egr-3; motif: NTGCGTGGGCGK 0.017380246670391 7313 115 60 0.521739130434783 0.00820456720907972
TF TF:M11547 Factor: foxo4; motif: NCGTMMACAN 0.0174889916257665 3449 63 22 0.349206349206349 0.00637866048129893
TF TF:M03567 Factor: Sp2; motif: NYSGCCCCGCCCCCY 0.0175699833303116 7710 112 61 0.544642857142857 0.00791180285343709
TF TF:M00144_1 Factor: Pax-5; motif: RRMSWGANWYCTNRAGCGKRACSRYNSM; match class: 1 0.0175704775112348 7128 88 47 0.534090909090909 0.00659371492704826
TF TF:M03914 Factor: KLF16; motif: GMCACGCCCCC 0.0176864294638872 3363 138 39 0.282608695652174 0.0115967885816235
TF TF:M10529_1 Factor: Sp1; motif: RGGGMGGRGSNGGGG; match class: 1 0.0179816926001592 2816 27 11 0.407407407407407 0.00390625
TF TF:M01175 Factor: CKROX; motif: SCCCTCCCC 0.0181250210408022 7292 54 32 0.592592592592593 0.00438837081733406
TF TF:M10591_1 Factor: BSX; motif: NNCGTTAN; match class: 1 0.018170911313966 2259 124 27 0.217741935483871 0.0119521912350598
TF TF:M09984_1 Factor: MAZ; motif: GGGGGAGGGGGNGRGRRRGNRG; match class: 1 0.018382390648685 5555 136 56 0.411764705882353 0.0100810081008101
TF TF:M07277_1 Factor: BTEB2; motif: RGGGNGKGGN; match class: 1 0.0184416626651552 4149 140 46 0.328571428571429 0.0110870089178115
TF TF:M09862 Factor: ZNF614; motif: NCYCWGCCYYNNN 0.0189768992135244 9361 126 78 0.619047619047619 0.00833244311505181
TF TF:M09968 Factor: KLF15; motif: RGGGMGGRGNNGGGGGNGG 0.0196582798841921 3157 52 18 0.346153846153846 0.00570161545771302
TF TF:M11546 Factor: foxo4; motif: NNGTMAACAN 0.0196582798841921 4235 63 25 0.396825396825397 0.00590318772136954
TF TF:M10591 Factor: BSX; motif: NNCGTTAN 0.0196582798841921 7760 114 62 0.543859649122807 0.00798969072164948
TF TF:M04849_1 Factor: RelA-p65; motif: AAASTCCC; match class: 1 0.0196641619494367 1170 4 3 0.75 0.00256410256410256
TF TF:M01744 Factor: REX1; motif: AANATGGCKGCN 0.0203748974758361 628 24 5 0.208333333333333 0.00796178343949045
TF TF:M10438 Factor: ZF5; motif: GGSGCGCGS 0.0208200352297593 16228 130 120 0.923076923076923 0.00739462657135815
TF TF:M04108 Factor: RUNX2; motif: WAACCGCAA 0.0208953576275538 1174 35 8 0.228571428571429 0.00681431005110733
TF TF:M11884 Factor: Pax-4a; motif: TTYACGCWTSANYGMACN 0.021028335531363 348 140 9 0.0642857142857143 0.0258620689655172
TF TF:M08523 Factor: E2F-1:TBR2; motif: NGGTGNNANGGCGCNNTNNCRNNN 0.0212395616873164 12160 141 105 0.74468085106383 0.00863486842105263
TF TF:M11221 Factor: CREB1; motif: RTGACGYGTCAN 0.0213072887441066 9677 139 87 0.62589928057554 0.00899038958354862
TF TF:M00453 Factor: IRF-7; motif: TNSGAAWNCGAAANTNNN 0.0216690940257462 3082 22 10 0.454545454545455 0.00324464633354964
TF TF:M12227_1 Factor: ZIC4; motif: NNCCNCCCRYNGYGN; match class: 1 0.0219937199341412 5898 141 60 0.425531914893617 0.0101729399796541
TF TF:M11530 Factor: E2F-2; motif: NWTTTGGCGCCAWWNN 0.0219937199341412 14593 137 117 0.854014598540146 0.0080175426574385
TF TF:M10628 Factor: NKX3A; motif: NTCGTTAN 0.0219937199341412 4543 137 48 0.35036496350365 0.0105657054809597
TF TF:M07370 Factor: YY1; motif: NNNNAARATGGNNNN 0.0219937199341412 5811 126 54 0.428571428571429 0.00929272070211667
TF TF:M00938 Factor: E2F-1; motif: TTGGCGCGRAANNGNM 0.0219937199341412 7334 141 71 0.50354609929078 0.00968093809653668
TF TF:M11533 Factor: E2F-1; motif: NTTTTGGCGCCAWWWN 0.0219937199341412 13105 141 111 0.787234042553192 0.00847004959938955
TF TF:M12231_1 Factor: LRF; motif: NCGACCACCGN; match class: 1 0.0223423565460647 5126 80 34 0.425 0.00663285212641436
TF TF:M11579 Factor: foxl2; motif: NNYGTAAACAN 0.0223423565460647 5888 63 31 0.492063492063492 0.00526494565217391
TF TF:M08342_1 Factor: HOXB2:TBR2; motif: NNGTGNTAATKN; match class: 1 0.0224501859881598 199 112 6 0.0535714285714286 0.0301507537688442
TF TF:M07370_1 Factor: YY1; motif: NNNNAARATGGNNNN; match class: 1 0.0225793562479659 1076 122 16 0.131147540983607 0.0148698884758364
TF TF:M04691_1 Factor: Kaiso; motif: TCTCGCGAG; match class: 1 0.0225793562479659 10488 135 90 0.666666666666667 0.0085812356979405
TF TF:M07436 Factor: WT1; motif: NNGGGNGGGSGN 0.0225946155083663 6182 138 61 0.442028985507246 0.00986735684244581
TF TF:M10071 Factor: Sp1; motif: NGGGGGCGGGGCCNGGGGGGGG 0.022611341724773 8495 112 65 0.580357142857143 0.00765155974102413
TF TF:M01104 Factor: MOVO-B; motif: GNGGGGG 0.022611341724773 10261 141 92 0.652482269503546 0.00896598772049508
TF TF:M04869_1 Factor: Egr-1; motif: GCGCATGCG; match class: 1 0.0226269511873717 10253 136 89 0.654411764705882 0.00868038622842095
TF TF:M10529 Factor: Sp1; motif: RGGGMGGRGSNGGGG 0.0226269511873717 6891 130 63 0.484615384615385 0.00914235959947758
TF TF:M08875 Factor: E2F; motif: NNTTTCGCGCN 0.0226276955266586 6203 135 60 0.444444444444444 0.00967273899725939
TF TF:M08020 Factor: YY2; motif: NNCCGCCATTW 0.0231719141677694 1331 32 8 0.25 0.00601051840721262
TF TF:M09898_1 Factor: Egr-2; motif: GNGRRNGWGKGGGNGGRG; match class: 1 0.0235273736137481 2541 125 29 0.232 0.0114128295946478
TF TF:M10681 Factor: HPX42B; motif: NNYNATTANN 0.0235273736137481 2469 41 13 0.317073170731707 0.0052652895909275
TF TF:M03967_1 Factor: ELF3; motif: WACCCGGAAGTAN; match class: 1 0.0235273736137481 1972 69 16 0.231884057971014 0.00811359026369168
TF TF:M09761_1 Factor: EGR1; motif: NGNGKGGGYGGNGS; match class: 1 0.0236994937273606 1568 136 22 0.161764705882353 0.014030612244898
TF TF:M11882 Factor: pax-6; motif: NYACGCNYSANYGMNCN 0.02392257060433 15490 130 116 0.892307692307692 0.00748870238863783
TF TF:M02090 Factor: E2F-4; motif: GCGGGAAANA 0.0243831116722497 11966 136 100 0.735294117647059 0.00835701153267591
TF TF:M11638 Factor: Sox-4; motif: NAACAAAGRN 0.0245919478731987 2748 138 33 0.239130434782609 0.0120087336244541
TF TF:M00209 Factor: NF-Y; motif: NCTGATTGGYTASY 0.0247806504455601 3776 42 17 0.404761904761905 0.0045021186440678
TF TF:M11452_1 Factor: Elf-1; motif: NANGCGGAAGTR; match class: 1 0.0249061427622367 1696 32 9 0.28125 0.00530660377358491
TF TF:M00737 Factor: E2F-1:DP-2; motif: TTTSSCGC 0.0258843410052874 8771 127 74 0.582677165354331 0.00843689431079694
TF TF:M01199 Factor: RNF96; motif: BCCCGCRGCC 0.0265382713911203 8473 129 73 0.565891472868217 0.00861560250206538
TF TF:M10071_1 Factor: Sp1; motif: NGGGGGCGGGGCCNGGGGGGGG; match class: 1 0.0274358099961518 4623 140 49 0.35 0.0105991780229288
TF TF:M04515_1 Factor: E2F-1; motif: WWTGGCGCCAAA; match class: 1 0.0274358099961518 12173 130 97 0.746153846153846 0.00796845477696542
TF TF:M05439 Factor: RREB-1; motif: GGGWCSA 0.0275361317066398 8635 141 80 0.567375886524823 0.00926462072958888
TF TF:M08398 Factor: POU2F1:Elk-1; motif: ACCGGAWATGCAW 0.0275361317066398 7882 13 11 0.846153846153846 0.00139558487693479
TF TF:M03981 Factor: ETV3; motif: ACCGGAAGTN 0.0275361317066398 2327 34 11 0.323529411764706 0.00472711645896003
TF TF:M08525 Factor: E2F-1:HES-7; motif: GGCRCGTGSYNNWNGGCGCSM 0.0275361317066398 17065 125 119 0.952 0.00697333723996484
TF TF:M10005 Factor: NF-YA; motif: NYRRCCAATCAGAR 0.0283497793852005 2225 118 25 0.211864406779661 0.0112359550561798
TF TF:M02023_1 Factor: MAZ; motif: NKGGGAGGGGRGGR; match class: 1 0.0284600378942798 3112 124 33 0.266129032258065 0.0106041131105398
TF TF:M00483_1 Factor: ATF6; motif: TGACGTGG; match class: 1 0.0285172485507019 246 97 6 0.0618556701030928 0.024390243902439
TF TF:M04683_1 Factor: NF-YA; motif: YTCTSATTGGYYRN; match class: 1 0.0285509616297728 185 87 5 0.0574712643678161 0.027027027027027
TF TF:M10067 Factor: Sox-2; motif: NNCCTTTGTNYYN 0.0290465400729705 6131 138 60 0.434782608695652 0.00978633175664655
TF TF:M01888 Factor: Smad3; motif: NGNCAGACASNNN 0.0290465400729705 4104 24 12 0.5 0.00292397660818713
TF TF:M09905 Factor: SAP-1; motif: NNCCGGAAGTGN 0.0290984071105815 8273 52 33 0.634615384615385 0.00398887948748942
TF TF:M09892_1 Factor: E2F-1; motif: NNNNGGCGGGAARN; match class: 1 0.0290984071105815 9162 136 81 0.595588235294118 0.00884086444007859
TF TF:M01594_1 Factor: TCF-3; motif: NCTTTGWTNTKYW; match class: 1 0.0295415367682013 823 134 14 0.104477611940299 0.0170109356014581
TF TF:M03922 Factor: SP4; motif: NWRGCCACGCCCMCTYN 0.0300588506501246 6046 140 60 0.428571428571429 0.00992391663910023
TF TF:M04826 Factor: p300; motif: ACNTCCG 0.030778104783964 17806 141 137 0.971631205673759 0.0076940357182972
TF TF:M01972_1 Factor: EGR-1; motif: TGCGTGGGCGK; match class: 1 0.0308192696608479 1472 94 16 0.170212765957447 0.0108695652173913
TF TF:M09966 Factor: Kaiso; motif: SARNYCTCGCGAGAN 0.0310140854383334 2356 125 27 0.216 0.0114601018675722
TF TF:M09834 Factor: ZNF148; motif: NNNNNNCCNNCCCCTCCCCCACCCN 0.0310787363000079 6953 138 66 0.478260869565217 0.00949230547964907
TF TF:M12230 Factor: LRF; motif: RCGACCACCNN 0.031120604993427 8543 11 10 0.909090909090909 0.00117054898747513
TF TF:M00292 Factor: Freac-4; motif: CTWAWGTAAACANWGN 0.0318817631324989 2722 73 20 0.273972602739726 0.00734753857457752
TF TF:M09632 Factor: Kaiso; motif: GNTCTCGCGAGRNNNNGGN 0.0318817631324989 3001 62 19 0.306451612903226 0.00633122292569144
TF TF:M11401_1 Factor: Fli-1; motif: NACCGGATATCCGGTN; match class: 1 0.0318817631324989 11801 128 93 0.7265625 0.00788068807728159
TF TF:M10942 Factor: VSX1; motif: NTCRTTAN 0.0318817631324989 3019 134 34 0.253731343283582 0.0112620072871812
TF TF:M10945 Factor: VSX1; motif: NTCRTTAN 0.0318817631324989 3019 134 34 0.253731343283582 0.0112620072871812
TF TF:M10936 Factor: CHX10; motif: NTCRTTAN 0.0318817631324989 3019 134 34 0.253731343283582 0.0112620072871812
TF TF:M10563 Factor: Msx-1; motif: NTCRTTAN 0.0318817631324989 3019 134 34 0.253731343283582 0.0112620072871812
TF TF:M10939 Factor: CHX10; motif: NTCRTTAN 0.0318817631324989 3019 134 34 0.253731343283582 0.0112620072871812
TF TF:M07617_1 Factor: Sp4; motif: SCCCCKCCCCCSN; match class: 1 0.0318817631324989 901 138 15 0.108695652173913 0.0166481687014428
TF TF:M01973_1 Factor: PLAG1; motif: CCCCCKWNNNGGSCCC; match class: 1 0.0318817631324989 2398 16 7 0.4375 0.00291909924937448
TF TF:M05327 Factor: WT1; motif: NGCGGGGGGGTSMMCYN 0.0318817631324989 5509 135 54 0.4 0.00980214194953712
TF TF:M10874 Factor: alx3; motif: NKCRTTAN 0.0318817631324989 3019 134 34 0.253731343283582 0.0112620072871812
TF TF:M07084 Factor: E2F-4; motif: NGGCGGGAARN 0.0318817631324989 10834 136 92 0.676470588235294 0.00849178512091564
TF TF:M10747 Factor: GSH2; motif: NTCRTTAN 0.0318817631324989 3019 134 34 0.253731343283582 0.0112620072871812
TF TF:M09862_1 Factor: ZNF614; motif: NCYCWGCCYYNNN; match class: 1 0.0320934108662061 4193 136 44 0.323529411764706 0.0104936799427617
TF TF:M04683 Factor: NF-YA; motif: YTCTSATTGGYYRN 0.0328254232135786 1657 117 20 0.170940170940171 0.012070006035003
TF TF:M07372 Factor: AML2; motif: TGTGGTNNN 0.0333097003171419 567 9 3 0.333333333333333 0.00529100529100529
TF TF:M11430_1 Factor: PEA3; motif: NACCGGAAGTN; match class: 1 0.0336497164511191 4902 52 23 0.442307692307692 0.00469196246430029
TF TF:M04110_1 Factor: RUNX3; motif: NRACCGCANWAACCRCAN; match class: 1 0.0337970787259395 3764 130 39 0.3 0.0103613177470776
TF TF:M11883 Factor: pax-6; motif: NYACGCNTSRNYGCNYN 0.033992326435179 13445 130 104 0.8 0.00773521755299368
TF TF:M04863_1 Factor: TF3C-beta; motif: CCNGGAGGGCTTCCTGGAGGAG; match class: 1 0.033992326435179 8573 125 71 0.568 0.00828181500058323
TF TF:M01303 Factor: SP1; motif: GGGGYGGGGNS 0.0341117194181228 7898 141 74 0.524822695035461 0.00936946062294252
TF TF:M01308_1 Factor: Sox-4; motif: AACAAWGR; match class: 1 0.0349195916611404 107 45 3 0.0666666666666667 0.0280373831775701
TF TF:M11586 Factor: foxj3; motif: ACGTAAACAN 0.0350499968945354 1252 63 11 0.174603174603175 0.00878594249201278
TF TF:M03977 Factor: ETS1; motif: ACCGGAARYN 0.0351455942855596 10512 140 92 0.657142857142857 0.00875190258751903
TF TF:M02052 Factor: EHF; motif: CSCGGAARTN 0.0351455942855596 10107 124 80 0.645161290322581 0.00791530622340952
TF TF:M04413_1 Factor: NKX3-1; motif: NCCACTTAA; match class: 1 0.0351853883235123 62 78 3 0.0384615384615385 0.0483870967741935
TF TF:M00691_1 Factor: ATF-1; motif: CYYTGACGTCA; match class: 1 0.0359277417267824 854 105 12 0.114285714285714 0.0140515222482436
TF TF:M03988 Factor: FLI1; motif: ACCGGAARTN 0.0361325415364368 8318 70 42 0.6 0.00504929069487858
TF TF:M09918_1 Factor: Pet-1; motif: GCNGGAAGYG; match class: 1 0.0361325415364368 7159 126 62 0.492063492063492 0.00866042743399916
TF TF:M11530_1 Factor: E2F-2; motif: NWTTTGGCGCCAWWNN; match class: 1 0.0363972383730315 13449 141 112 0.794326241134752 0.0083277567105361
TF TF:M06105 Factor: ZNF705D; motif: NCCAAAAAAAYY 0.0363972383730315 150 70 4 0.0571428571428571 0.0266666666666667
TF TF:M09896 Factor: E2F-7; motif: GRGGCGGGAANNN 0.0370028103792303 9927 135 85 0.62962962962963 0.00856250629596051
TF TF:M09918 Factor: Pet-1; motif: GCNGGAAGYG 0.0371912952896826 13610 133 107 0.804511278195489 0.00786186627479794
TF TF:M11391 Factor: Erg; motif: NACCGGATATCCGGTN 0.0372984613705629 10082 128 82 0.640625 0.00813330688355485
TF TF:M06271 Factor: ZNF284; motif: NGGTCRGKAAGA 0.0383244138164184 45 112 3 0.0267857142857143 0.0666666666666667
TF TF:M04516_1 Factor: E2F-1; motif: TTTGGCGCCAAA; match class: 1 0.0386815077627895 10227 130 84 0.646153846153846 0.0082135523613963
TF TF:M09761 Factor: EGR1; motif: NGNGKGGGYGGNGS 0.0386815077627895 5162 126 48 0.380952380952381 0.00929872142580395
TF TF:M07277 Factor: BTEB2; motif: RGGGNGKGGN 0.0388000401469253 8492 141 78 0.553191489361702 0.00918511540273198
TF TF:M00139 Factor: AhR; motif: CCYCNRRSTNGCGTGASA 0.0388000401469253 3728 141 41 0.290780141843972 0.0109978540772532
TF TF:M07296 Factor: MAF; motif: GCTGAGTCAN 0.0388000401469253 5670 57 27 0.473684210526316 0.00476190476190476
TF TF:M08457_1 Factor: ER71:SREBP-2; motif: NTSACGTGACGGAARY; match class: 1 0.0388000401469253 5591 123 50 0.40650406504065 0.00894294401717045
TF TF:M09894 Factor: E2F-4; motif: SNGGGCGGGAANN 0.0389311958350695 16194 136 124 0.911764705882353 0.00765715697171792
TF TF:M12160_1 Factor: KLF15; motif: RCCMCRCCCMCN; match class: 1 0.0397251550895741 8031 89 50 0.561797752808989 0.00622587473540032
TF TF:M11880_1 Factor: pax-6; motif: NYACGCWTSANYGMNCN; match class: 1 0.0397251550895741 7046 126 61 0.484126984126984 0.00865739426625036
TF TF:M11449_1 Factor: Elf-1; motif: NANCCGGAAGTN; match class: 1 0.0397251550895741 695 39 6 0.153846153846154 0.00863309352517986
TF TF:M04287 Factor: BARHL2; motif: NNTAAAYGNN 0.0400505948554341 4416 117 40 0.341880341880342 0.00905797101449275
TF TF:M02059 Factor: ELK-1; motif: ACCGGAAGTN 0.0403878527153241 9423 114 70 0.614035087719298 0.00742863207046588
TF TF:M04869 Factor: Egr-1; motif: GCGCATGCG 0.0406121489854877 11232 136 94 0.691176470588235 0.00836894586894587
TF TF:M11601 Factor: TCF-1; motif: ACATCGRGRCGCTGW 0.0412468115875602 14823 90 79 0.877777777777778 0.0053295554206301
TF TF:M11381 Factor: ESE-1; motif: SATKGCGGATGCN 0.041523795440593 15720 138 123 0.891304347826087 0.00782442748091603
TF TF:M07234 Factor: YY1; motif: CAARATGGCNGC 0.0418186240960948 6045 115 50 0.434782608695652 0.00827129859387924
TF TF:M12186_1 Factor: BTEB4; motif: NCCACGCCCM; match class: 1 0.0418719020666235 3958 138 42 0.304347826086957 0.010611419909045
TF TF:M11271_1 Factor: JunD; motif: NRTGACGCAYN; match class: 1 0.0425084745685514 1497 133 20 0.150375939849624 0.0133600534402138
TF TF:M11529 Factor: E2F-2; motif: GCGCGCGCNCS 0.0425084745685514 16263 130 119 0.915384615384615 0.00731722314456127
TF TF:M04863 Factor: TF3C-beta; motif: CCNGGAGGGCTTCCTGGAGGAG 0.0427261769670162 13618 128 103 0.8046875 0.00756351887208107
TF TF:M03925 Factor: YY2; motif: NCCGCCATNTY 0.0427261769670162 4641 133 46 0.345864661654135 0.0099116569704805
TF TF:M08281 Factor: Fli-1:C/EBPbeta; motif: RNCGGAWRTTGCGCAAY 0.0433640859649356 7571 81 44 0.54320987654321 0.00581164971602166
TF TF:M11639 Factor: Sox-4; motif: NAACAAAGRN 0.0438553488139454 3125 138 35 0.253623188405797 0.0112
TF TF:M07395_1 Factor: Sp1; motif: NGGGGCGGGGN; match class: 1 0.0443863257491089 6334 95 44 0.463157894736842 0.00694663719608462
TF TF:M01652_1 Factor: p53; motif: RGRCWWGYCYNGRCWWGYYY; match class: 1 0.0445273615446725 5253 31 16 0.516129032258065 0.00304587854559299
TF TF:M07045 Factor: IRF-1; motif: NNRAAANNGAAASN 0.0445850410062311 535 22 4 0.181818181818182 0.00747663551401869
TF TF:M04788 Factor: IRF-1; motif: STTTCACTTTCNNT 0.0447697883781585 536 22 4 0.181818181818182 0.00746268656716418
TF TF:M00736_1 Factor: E2F-1:DP-1; motif: TTTCSCGC; match class: 1 0.0451472616678748 4639 130 45 0.346153846153846 0.00970036645828842
TF TF:M04710 Factor: CHD2; motif: TCTCGCGAG 0.0465962829740605 14109 135 111 0.822222222222222 0.00786731873272379
TF TF:M08826 Factor: NF-E4; motif: GTGAGGS 0.0465962829740605 11318 123 86 0.699186991869919 0.00759851563880544
TF TF:M07605 Factor: LEF-1; motif: NANNWWCAAAGNN 0.0467025525415789 1722 49 11 0.224489795918367 0.00638792102206736
TF TF:M11490_1 Factor: LBP-1; motif: NRCCGGTNNNNACCGGYN; match class: 1 0.0467025525415789 5988 103 45 0.436893203883495 0.00751503006012024
TF TF:M01882 Factor: IRF-2; motif: NNRAAAGTGAAASNNA 0.0467025525415789 258 22 3 0.136363636363636 0.0116279069767442
TF TF:M05464 Factor: Sall1; motif: NAKKCGKAAAKG 0.0467025525415789 923 64 9 0.140625 0.00975081256771398
TF TF:M11401 Factor: Fli-1; motif: NACCGGATATCCGGTN 0.0468037323408969 11952 128 93 0.7265625 0.00778112449799197
TF TF:M09859_1 Factor: NF90; motif: NCCNCWGCCYCCNC; match class: 1 0.047052394632052 1011 118 14 0.11864406779661 0.0138476755687438
TF TF:M01118 Factor: WT1; motif: SMCNCCNSC 0.0474478475544706 6808 54 29 0.537037037037037 0.00425969447708578
TF TF:M09973 Factor: CPBP; motif: GNNRGGGHGGGGNNGGGRN 0.0475228497036756 10853 126 85 0.674603174603175 0.00783193587026629
TF TF:M11404 Factor: Fli-1; motif: NACCGGAARTN 0.0475228497036756 8743 70 43 0.614285714285714 0.00491822029051813
TF TF:M11882_1 Factor: pax-6; motif: NYACGCNYSANYGMNCN; match class: 1 0.0478732160707992 11423 130 91 0.7 0.00796638361201086
TF TF:M10026_1 Factor: PATZ; motif: GGGGNGGGGGMKGGRRNGGNRN; match class: 1 0.0479303975990836 4894 111 41 0.369369369369369 0.00837760523089497
TF TF:M00004_1 Factor: c-Myb; motif: NCNRNNGRCNGTTGGKGG; match class: 1 0.0483039403909941 1883 33 9 0.272727272727273 0.00477960701009028
TF TF:M06377 Factor: ZNF773; motif: GGGTGGCCGC 0.0485207220506975 277 101 6 0.0594059405940594 0.0216606498194946
TF TF:M06576 Factor: ZNF419; motif: GGGTGGCCGC 0.0485207220506975 277 101 6 0.0594059405940594 0.0216606498194946
TF TF:M10436 Factor: YY1; motif: CAANATGGCGGC 0.0487390353226358 8220 115 63 0.547826086956522 0.00766423357664234
TF TF:M07457 Factor: Hoxa9; motif: NTTAAWTAMA 0.0491104880921437 4710 23 12 0.521739130434783 0.00254777070063694
TF TF:M01173_1 Factor: SREBP-1; motif: NSNNTCACNCCANNN; match class: 1 0.0493124902182538 721 40 6 0.15 0.00832177531206657
TF TF:M08226_1 Factor: Elk-1:Pax-9; motif: ACCGGAACYACGCWYSANTG; match class: 1 0.0493124902182538 5604 56 26 0.464285714285714 0.0046395431834404
TF TF:M00069_1 Factor: YY1; motif: NNNCGGCCATCTTGNCTSNW; match class: 1 0.0493282363033532 2205 113 23 0.20353982300885 0.0104308390022676
TF TF:M10887_1 Factor: PRX-2; motif: NNCRTTAN; match class: 1 0.0493282363033532 1198 134 17 0.126865671641791 0.0141903171953255
TF TF:M10885_1 Factor: PRX-2; motif: NKCGTTAN; match class: 1 0.0493282363033532 1198 134 17 0.126865671641791 0.0141903171953255
TF TF:M02062 Factor: Erg; motif: ACCGGAAGTN 0.0496134468142398 8056 53 32 0.60377358490566 0.00397219463753724
TF TF:M10785_1 Factor: hoxa9; motif: RTCGTWANNN; match class: 1 0.0496134468142398 1160 34 7 0.205882352941176 0.00603448275862069
TF TF:M00649 Factor: MAZ; motif: GGGGAGGG 0.0496134468142398 9327 54 36 0.666666666666667 0.00385976198134448
TF TF:M11451_1 Factor: Elf-1; motif: NANCCGGAAGTN; match class: 1 0.0498248663577686 2112 47 12 0.25531914893617 0.00568181818181818
TF TF:M12057 Factor: ZBP99; motif: GCCCMTCCCCCR 0.0498248663577686 5225 133 50 0.37593984962406 0.00956937799043062
TF TF:M04107_1 Factor: RUNX2; motif: WRACCGCANWAACCGCAN; match class: 1 0.0498248663577686 6444 141 62 0.439716312056738 0.00962135319677219
TF TF:M08472_1 Factor: Fli-1:E2A; motif: NCCGGAWRCASCTGN; match class: 1 0.0498248663577686 2240 39 11 0.282051282051282 0.00491071428571429
TF TF:M08224_1 Factor: Elk-1:Pax-1; motif: ACCGGAACTACGCWTSANTG; match class: 1 0.0498248663577686 2748 56 16 0.285714285714286 0.00582241630276565
TF TF:M11427 Factor: PEA3; motif: NACCGGAAGTN 0.0498248663577686 10585 114 76 0.666666666666667 0.00717997165800661
TF TF:M01588 Factor: GKLF; motif: GCCMCRCCCNNN 0.049899164255472 8944 140 80 0.571428571428571 0.00894454382826476

pEpiTd14 transcription factor target enrichment of top program genes

TF enrichment of pEpiTd14
Possible regulators of activation of pEpiTd14 in epithelial cells. (Left) pearson correlation of TF expression and gene expression program activatity in Epithelial cells, (right) negative log p-value for enrichment of TF binding sites among top uniqueness weighted genes for the gene program. Blue bars indicate significant TFs meeting the following criteria: FDR<0.1, overlap > 2, Corr. R > 0, permutation based p-value < 0.05.