pEpiTp01 program activity among Epithelial cells

Activation of pEpiTp01
pEpiTp01 gene program activation in Epithelial cells. (Top) Activation of program across all epithelial cells. (Bottom) Activation in MMRd (left), MMRp (middle), and normal epithelial cells (right).

Epithelial cell compositional overview

Overview of epithelial cell composition
Overview of epithelial cell composition. A tSNE plot colored by: (left) MMR status of epithelial cells, (middle) specimen, (righ) epithelial cell sub-type.
Gene program activation of pEpiTp01 by different cell subtypes
pEpiTp01 gene program activation among cells of different subtypes (Epithelial cells).

pEpiTp01 top program genes

Top genes of pEpiTp01 program
Bar plots showing the top genes for each gene program, ranked by (left) unique weights, (right) raw weights.

pEpiTp01 gene-set enrichment of top program genes (using g-profiler)

GSEA wth gene profiler of pEpiTp01
pEpiTp01 gene-set enrichment summary using g-profiler webtool.
Source termID Name Padj Tsize Qsize Overlap Precision Recall
GO:BP GO:0048524 positive regulation of viral process 0.00198322396796407 91 98 7 0.0714285714285714 0.0769230769230769
GO:BP GO:0090150 establishment of protein localization to membrane 0.00198322396796407 351 19 6 0.315789473684211 0.0170940170940171
GO:BP GO:0006413 translational initiation 0.00635219896512151 201 4 3 0.75 0.0149253731343284
GO:BP GO:0044403 biological process involved in symbiotic interaction 0.00745695079270589 1001 132 21 0.159090909090909 0.020979020979021
GO:BP GO:0006886 intracellular protein transport 0.00745695079270589 1186 88 18 0.204545454545455 0.015177065767285
GO:BP GO:0051204 protein insertion into mitochondrial membrane 0.00745695079270589 48 117 5 0.0427350427350427 0.104166666666667
GO:BP GO:0072594 establishment of protein localization to organelle 0.00745695079270589 584 19 6 0.315789473684211 0.0102739726027397
GO:BP GO:1900740 positive regulation of protein insertion into mitochondrial membrane involved in apoptotic signaling pathway 0.00745695079270589 26 117 4 0.0341880341880342 0.153846153846154
GO:BP GO:1900739 regulation of protein insertion into mitochondrial membrane involved in apoptotic signaling pathway 0.00745695079270589 26 117 4 0.0341880341880342 0.153846153846154
GO:BP GO:0090151 establishment of protein localization to mitochondrial membrane 0.00745695079270589 53 19 3 0.157894736842105 0.0566037735849057
GO:BP GO:0016071 mRNA metabolic process 0.00831201502906416 874 17 6 0.352941176470588 0.0068649885583524
GO:BP GO:0042886 amide transport 0.00831201502906416 2007 88 23 0.261363636363636 0.0114598903836572
GO:BP GO:0071214 cellular response to abiotic stimulus 0.00831201502906416 339 122 10 0.0819672131147541 0.0294985250737463
GO:BP GO:0043603 cellular amide metabolic process 0.00831201502906416 1241 117 21 0.179487179487179 0.0169218372280419
GO:BP GO:0006518 peptide metabolic process 0.00831201502906416 955 113 17 0.150442477876106 0.0178010471204188
GO:BP GO:0043903 regulation of biological process involved in symbiotic interaction 0.00831201502906416 203 124 8 0.0645161290322581 0.0394088669950739
GO:BP GO:0006605 protein targeting 0.00831201502906416 441 18 5 0.277777777777778 0.0113378684807256
GO:BP GO:0044249 cellular biosynthetic process 0.00831201502906416 6154 24 18 0.75 0.00292492687682808
GO:BP GO:0008637 apoptotic mitochondrial changes 0.00831201502906416 126 129 7 0.0542635658914729 0.0555555555555556
GO:BP GO:0009058 biosynthetic process 0.00831201502906416 6340 24 18 0.75 0.0028391167192429
GO:BP GO:0009059 macromolecule biosynthetic process 0.00831201502906416 5114 24 16 0.666666666666667 0.00312866640594447
GO:BP GO:1902686 mitochondrial outer membrane permeabilization involved in programmed cell death 0.00831201502906416 65 122 5 0.040983606557377 0.0769230769230769
GO:BP GO:1902108 regulation of mitochondrial membrane permeability involved in apoptotic process 0.00831201502906416 69 122 5 0.040983606557377 0.072463768115942
GO:BP GO:0046907 intracellular transport 0.00831201502906416 1767 88 21 0.238636363636364 0.0118845500848896
GO:BP GO:1901576 organic substance biosynthetic process 0.00831201502906416 6248 24 18 0.75 0.0028809218950064
GO:BP GO:1901564 organonitrogen compound metabolic process 0.00831201502906416 6792 114 63 0.552631578947368 0.0092756183745583
GO:BP GO:1901030 positive regulation of mitochondrial outer membrane permeabilization involved in apoptotic signaling pathway 0.00831201502906416 36 117 4 0.0341880341880342 0.111111111111111
GO:BP GO:0104004 cellular response to environmental stimulus 0.00831201502906416 339 122 10 0.0819672131147541 0.0294985250737463
GO:BP GO:0050792 regulation of viral process 0.00831201502906416 192 124 8 0.0645161290322581 0.0416666666666667
GO:BP GO:0098781 ncRNA transcription 0.00831201502906416 110 117 6 0.0512820512820513 0.0545454545454545
GO:BP GO:0097345 mitochondrial outer membrane permeabilization 0.00831201502906416 57 122 5 0.040983606557377 0.087719298245614
GO:BP GO:0010467 gene expression 0.00831201502906416 6179 24 18 0.75 0.00291309273345201
GO:BP GO:0051205 protein insertion into membrane 0.00831201502906416 78 19 3 0.157894736842105 0.0384615384615385
GO:BP GO:0072657 protein localization to membrane 0.00831201502906416 665 19 6 0.315789473684211 0.00902255639097744
GO:BP GO:1902110 positive regulation of mitochondrial membrane permeability involved in apoptotic process 0.00831201502906416 63 122 5 0.040983606557377 0.0793650793650794
GO:BP GO:0001844 protein insertion into mitochondrial membrane involved in apoptotic signaling pathway 0.00831201502906416 30 117 4 0.0341880341880342 0.133333333333333
GO:BP GO:0010661 positive regulation of muscle cell apoptotic process 0.00831201502906416 36 122 4 0.0327868852459016 0.111111111111111
GO:BP GO:0016032 viral process 0.00831201502906416 942 132 19 0.143939393939394 0.0201698513800425
GO:BP GO:0015031 protein transport 0.00831201502906416 1929 88 22 0.25 0.0114048729911871
GO:BP GO:0035794 positive regulation of mitochondrial membrane permeability 0.00831201502906416 67 122 5 0.040983606557377 0.0746268656716418
GO:BP GO:0034645 cellular macromolecule biosynthetic process 0.00831201502906416 5051 24 16 0.666666666666667 0.00316768956642249
GO:BP GO:0022613 ribonucleoprotein complex biogenesis 0.00831201502906416 446 4 3 0.75 0.00672645739910314
GO:BP GO:0019538 protein metabolic process 0.00851959774494745 5808 114 56 0.491228070175439 0.00964187327823691
GO:BP GO:1905710 positive regulation of membrane permeability 0.00945190961087754 72 122 5 0.040983606557377 0.0694444444444444
GO:BP GO:0015833 peptide transport 0.0102421689624304 1971 88 22 0.25 0.0111618467782851
GO:BP GO:0010821 regulation of mitochondrion organization 0.0102421689624304 158 129 7 0.0542635658914729 0.0443037974683544
GO:BP GO:0045047 protein targeting to ER 0.0127124591360012 113 18 3 0.166666666666667 0.0265486725663717
GO:BP GO:0097190 apoptotic signaling pathway 0.0127124591360012 600 137 14 0.102189781021898 0.0233333333333333
GO:BP GO:0034613 cellular protein localization 0.0127124591360012 2014 88 22 0.25 0.0109235352532274
GO:BP GO:0010663 positive regulation of striated muscle cell apoptotic process 0.0127124591360012 17 122 3 0.0245901639344262 0.176470588235294
GO:BP GO:0010666 positive regulation of cardiac muscle cell apoptotic process 0.0127124591360012 17 122 3 0.0245901639344262 0.176470588235294
GO:BP GO:0046902 regulation of mitochondrial membrane permeability 0.0129338837564438 80 122 5 0.040983606557377 0.0625
GO:BP GO:0072599 establishment of protein localization to endoplasmic reticulum 0.0129338837564438 117 18 3 0.166666666666667 0.0256410256410256
GO:BP GO:0070727 cellular macromolecule localization 0.0129338837564438 2024 88 22 0.25 0.0108695652173913
GO:BP GO:0045184 establishment of protein localization 0.0133338771330011 2035 88 22 0.25 0.0108108108108108
GO:BP GO:0006368 transcription elongation from RNA polymerase II promoter 0.0133338771330011 88 113 5 0.0442477876106195 0.0568181818181818
GO:BP GO:1901028 regulation of mitochondrial outer membrane permeabilization involved in apoptotic signaling pathway 0.0133338771330011 46 117 4 0.0341880341880342 0.0869565217391304
GO:BP GO:0033036 macromolecule localization 0.0154823323691835 3218 94 31 0.329787234042553 0.00963331261653201
GO:BP GO:0006412 translation 0.0161446953960169 764 4 3 0.75 0.00392670157068063
GO:BP GO:0010822 positive regulation of mitochondrion organization 0.0161446953960169 86 122 5 0.040983606557377 0.0581395348837209
GO:BP GO:0050434 positive regulation of viral transcription 0.0161446953960169 24 98 3 0.0306122448979592 0.125
GO:BP GO:0071705 nitrogen compound transport 0.016875977042027 2322 90 24 0.266666666666667 0.0103359173126615
GO:BP GO:0043043 peptide biosynthetic process 0.0172918052062897 790 4 3 0.75 0.00379746835443038
GO:BP GO:0003081 regulation of systemic arterial blood pressure by renin-angiotensin 0.0176451309045611 24 103 3 0.029126213592233 0.125
GO:BP GO:0062197 cellular response to chemical stress 0.0180961322354174 365 132 10 0.0757575757575758 0.0273972602739726
GO:BP GO:0044271 cellular nitrogen compound biosynthetic process 0.0192489748455765 5017 24 15 0.625 0.00298983456248754
GO:BP GO:0070972 protein localization to endoplasmic reticulum 0.0192489748455765 146 18 3 0.166666666666667 0.0205479452054795
GO:BP GO:0090199 regulation of release of cytochrome c from mitochondria 0.0192489748455765 48 129 4 0.0310077519379845 0.0833333333333333
GO:BP GO:0048518 positive regulation of biological process 0.0192572186255684 6363 55 32 0.581818181818182 0.00502907433600503
GO:BP GO:0006508 proteolysis 0.0192572186255684 1836 94 21 0.223404255319149 0.011437908496732
GO:BP GO:0070585 protein localization to mitochondrion 0.0201103629430223 147 19 3 0.157894736842105 0.0204081632653061
GO:BP GO:2001238 positive regulation of extrinsic apoptotic signaling pathway 0.0201103629430223 48 137 4 0.0291970802919708 0.0833333333333333
GO:BP GO:2001235 positive regulation of apoptotic signaling pathway 0.0201103629430223 129 137 6 0.0437956204379562 0.0465116279069767
GO:BP GO:0019083 viral transcription 0.0201103629430223 181 98 6 0.0612244897959184 0.0331491712707182
GO:BP GO:0010823 negative regulation of mitochondrion organization 0.0201103629430223 51 129 4 0.0310077519379845 0.0784313725490196
GO:BP GO:0090559 regulation of membrane permeability 0.0201103629430223 95 122 5 0.040983606557377 0.0526315789473684
GO:BP GO:0033365 protein localization to organelle 0.0201103629430223 1017 19 6 0.315789473684211 0.00589970501474926
GO:BP GO:0051641 cellular localization 0.0201103629430223 3541 42 18 0.428571428571429 0.00508330979949167
GO:BP GO:0072655 establishment of protein localization to mitochondrion 0.0201103629430223 143 19 3 0.157894736842105 0.020979020979021
GO:BP GO:0019222 regulation of metabolic process 0.0201103629430223 7148 24 18 0.75 0.00251818690542809
GO:BP GO:0042493 response to drug 0.0205609768781604 396 31 5 0.161290322580645 0.0126262626262626
GO:BP GO:0000398 mRNA splicing, via spliceosome 0.0205609768781604 361 116 9 0.0775862068965517 0.0249307479224377
GO:BP GO:0000377 RNA splicing, via transesterification reactions with bulged adenosine as nucleophile 0.0205609768781604 361 116 9 0.0775862068965517 0.0249307479224377
GO:BP GO:0043604 amide biosynthetic process 0.0205609768781604 932 4 3 0.75 0.00321888412017167
GO:BP GO:0000375 RNA splicing, via transesterification reactions 0.0205609768781604 364 116 9 0.0775862068965517 0.0247252747252747
GO:BP GO:0010660 regulation of muscle cell apoptotic process 0.0205609768781604 94 129 5 0.0387596899224806 0.0531914893617021
GO:BP GO:0034599 cellular response to oxidative stress 0.0205609768781604 316 132 9 0.0681818181818182 0.0284810126582278
GO:BP GO:0045070 positive regulation of viral genome replication 0.0205609768781604 31 95 3 0.0315789473684211 0.0967741935483871
GO:BP GO:0007006 mitochondrial membrane organization 0.0205609768781604 151 19 3 0.157894736842105 0.0198675496688742
GO:BP GO:1903749 positive regulation of establishment of protein localization to mitochondrion 0.0205609768781604 58 117 4 0.0341880341880342 0.0689655172413793
GO:BP GO:0010468 regulation of gene expression 0.0208226777920003 5196 24 15 0.625 0.00288683602771363
GO:BP GO:0034641 cellular nitrogen compound metabolic process 0.0212311345765871 6563 24 17 0.708333333333333 0.00259027883589822
GO:BP GO:0090304 nucleic acid metabolic process 0.0216254176464008 5226 24 15 0.625 0.00287026406429392
GO:BP GO:0046483 heterocycle metabolic process 0.0222945053430977 5904 24 16 0.666666666666667 0.002710027100271
GO:BP GO:0051346 negative regulation of hydrolase activity 0.0225363692601155 470 132 11 0.0833333333333333 0.0234042553191489
GO:BP GO:0010657 muscle cell apoptotic process 0.0228150301130127 98 129 5 0.0387596899224806 0.0510204081632653
GO:BP GO:0009651 response to salt stress 0.0228774137828414 27 117 3 0.0256410256410256 0.111111111111111
GO:BP GO:0071702 organic substance transport 0.0233885774332125 2766 90 26 0.288888888888889 0.0093998553868402
GO:BP GO:0019080 viral gene expression 0.0235790128994186 199 98 6 0.0612244897959184 0.0301507537688442
GO:BP GO:0072593 reactive oxygen species metabolic process 0.0242067794596728 290 122 8 0.0655737704918033 0.0275862068965517
GO:BP GO:0016070 RNA metabolic process 0.02449740529028 4710 24 14 0.583333333333333 0.0029723991507431
GO:BP GO:0001836 release of cytochrome c from mitochondria 0.0246463424793951 59 129 4 0.0310077519379845 0.0677966101694915
GO:BP GO:0061024 membrane organization 0.0246463424793951 973 134 17 0.126865671641791 0.0174717368961973
GO:BP GO:0006354 DNA-templated transcription, elongation 0.0246463424793951 117 113 5 0.0442477876106195 0.0427350427350427
GO:BP GO:1901652 response to peptide 0.0246463424793951 551 51 7 0.137254901960784 0.0127041742286751
GO:BP GO:0044267 cellular protein metabolic process 0.0252227189932244 5229 114 49 0.429824561403509 0.00937081659973226
GO:BP GO:0006807 nitrogen compound metabolic process 0.0257675474574454 10078 117 82 0.700854700854701 0.00813653502679103
GO:BP GO:0006612 protein targeting to membrane 0.0271991169432945 204 18 3 0.166666666666667 0.0147058823529412
GO:BP GO:0003091 renal water homeostasis 0.0273193155633385 40 90 3 0.0333333333333333 0.075
GO:BP GO:0051649 establishment of localization in cell 0.0283226550860768 2813 42 15 0.357142857142857 0.0053323853537149
GO:BP GO:0042795 snRNA transcription by RNA polymerase II 0.0289913678287237 73 113 4 0.0353982300884956 0.0547945205479452
GO:BP GO:0006370 7-methylguanosine mRNA capping 0.0289913678287237 33 113 3 0.0265486725663717 0.0909090909090909
GO:BP GO:0036260 RNA capping 0.0290336783478405 34 113 3 0.0265486725663717 0.0882352941176471
GO:BP GO:0044265 cellular macromolecule catabolic process 0.0290336783478405 1231 19 6 0.315789473684211 0.00487408610885459
GO:BP GO:0050886 endocrine process 0.0290336783478405 82 103 4 0.0388349514563107 0.0487804878048781
GO:BP GO:0009452 7-methylguanosine RNA capping 0.0290336783478405 34 113 3 0.0265486725663717 0.0882352941176471
GO:BP GO:0009301 snRNA transcription 0.0290336783478405 74 113 4 0.0353982300884956 0.0540540540540541
GO:BP GO:0008104 protein localization 0.0290336783478405 2770 88 25 0.284090909090909 0.00902527075812274
GO:BP GO:0071407 cellular response to organic cyclic compound 0.0290336783478405 587 132 12 0.0909090909090909 0.020442930153322
GO:BP GO:1901360 organic cyclic compound metabolic process 0.0290336783478405 6201 24 16 0.666666666666667 0.00258022899532333
GO:BP GO:1903747 regulation of establishment of protein localization to mitochondrion 0.0290336783478405 72 117 4 0.0341880341880342 0.0555555555555556
GO:BP GO:0006611 protein export from nucleus 0.0300906635043698 185 117 6 0.0512820512820513 0.0324324324324324
GO:BP GO:0001990 regulation of systemic arterial blood pressure by hormone 0.0303999332240494 38 103 3 0.029126213592233 0.0789473684210526
GO:BP GO:0071426 ribonucleoprotein complex export from nucleus 0.0304667097694441 130 113 5 0.0442477876106195 0.0384615384615385
GO:BP GO:0071166 ribonucleoprotein complex localization 0.0309256803772287 131 113 5 0.0442477876106195 0.0381679389312977
GO:BP GO:0006396 RNA processing 0.0309256803772287 964 117 15 0.128205128205128 0.0155601659751037
GO:BP GO:0006820 anion transport 0.0309256803772287 2889 90 26 0.288888888888889 0.00899965385946694
GO:BP GO:0046782 regulation of viral transcription 0.031449510559133 41 98 3 0.0306122448979592 0.0731707317073171
GO:BP GO:0007565 female pregnancy 0.034132525257692 198 46 4 0.0869565217391304 0.0202020202020202
GO:BP GO:0071478 cellular response to radiation 0.0357331482843739 196 117 6 0.0512820512820513 0.0306122448979592
GO:BP GO:0051248 negative regulation of protein metabolic process 0.0358313465204017 1151 132 18 0.136363636363636 0.0156385751520417
GO:BP GO:0031503 protein-containing complex localization 0.0359091474669645 289 80 6 0.075 0.0207612456747405
GO:BP GO:0043933 protein-containing complex subunit organization 0.0360104602460363 1963 67 16 0.238805970149254 0.00815078960774325
GO:BP GO:2001233 regulation of apoptotic signaling pathway 0.0361572082449505 363 137 9 0.0656934306569343 0.0247933884297521
GO:BP GO:0044238 primary metabolic process 0.0369530990326964 10584 117 84 0.717948717948718 0.00793650793650794
GO:BP GO:0006139 nucleobase-containing compound metabolic process 0.0369714670147577 5746 24 15 0.625 0.00261051166028542
GO:BP GO:0009057 macromolecule catabolic process 0.0371005597479663 1468 50 11 0.22 0.00749318801089918
GO:BP GO:0006810 transport 0.0389262770579889 5224 5 5 1 0.000957120980091884
GO:BP GO:0006403 RNA localization 0.0389262770579889 238 68 5 0.0735294117647059 0.0210084033613445
GO:BP GO:0006405 RNA export from nucleus 0.039307264133227 143 113 5 0.0442477876106195 0.034965034965035
GO:BP GO:0051168 nuclear export 0.0401493955323627 204 117 6 0.0512820512820513 0.0294117647058824
GO:BP GO:0070507 regulation of microtubule cytoskeleton organization 0.0409341300491308 145 68 4 0.0588235294117647 0.0275862068965517
GO:BP GO:0006397 mRNA processing 0.0415753804672344 532 116 10 0.0862068965517241 0.018796992481203
GO:BP GO:0051234 establishment of localization 0.0427872640091627 5372 5 5 1 0.000930752047654505
GO:BP GO:0044237 cellular metabolic process 0.0428303204600723 10871 124 90 0.725806451612903 0.00827890718425168
GO:BP GO:0060255 regulation of macromolecule metabolic process 0.0460122570466257 6603 24 16 0.666666666666667 0.00242314099651673
GO:BP GO:0010951 negative regulation of endopeptidase activity 0.0461471937834412 253 132 7 0.053030303030303 0.0276679841897233
GO:BP GO:0008380 RNA splicing 0.0464812205487269 456 116 9 0.0775862068965517 0.0197368421052632
GO:BP GO:0045069 regulation of viral genome replication 0.0464812205487269 84 124 4 0.032258064516129 0.0476190476190476
GO:BP GO:0044706 multi-multicellular organism process 0.0464812205487269 227 46 4 0.0869565217391304 0.0176211453744493
GO:BP GO:0006725 cellular aromatic compound metabolic process 0.0472908893196291 5956 24 15 0.625 0.00251846877098724
GO:BP GO:0003044 regulation of systemic arterial blood pressure mediated by a chemical signal 0.0487515312780254 50 103 3 0.029126213592233 0.06
GO:BP GO:0010629 negative regulation of gene expression 0.0487761409945194 1460 19 6 0.315789473684211 0.00410958904109589
GO:BP GO:1901575 organic substance catabolic process 0.0487761409945194 2267 131 28 0.213740458015267 0.0123511248345831
GO:BP GO:0043154 negative regulation of cysteine-type endopeptidase activity involved in apoptotic process 0.0487761409945194 81 132 4 0.0303030303030303 0.0493827160493827
GO:BP GO:0031123 RNA 3'-end processing 0.0492762679853665 157 113 5 0.0442477876106195 0.0318471337579618
GO:BP GO:0006839 mitochondrial transport 0.0495344835939222 284 19 3 0.157894736842105 0.0105633802816901
GO:CC GO:0032991 protein-containing complex 0.0018111479445879 5548 68 38 0.558823529411765 0.00684931506849315
GO:CC GO:1990904 ribonucleoprotein complex 0.00441503264207548 688 17 6 0.352941176470588 0.00872093023255814
GO:CC GO:0005634 nucleus 0.00586619473036919 7592 55 37 0.672727272727273 0.00487355110642782
GO:CC GO:0005829 cytosol 0.00586619473036919 5303 49 27 0.551020408163265 0.00509145766547237
GO:CC GO:0031974 membrane-enclosed lumen 0.00900601311004153 5565 122 55 0.450819672131148 0.00988319856244385
GO:CC GO:0070013 intracellular organelle lumen 0.00900601311004153 5402 122 54 0.442622950819672 0.00999629766753054
GO:CC GO:0043233 organelle lumen 0.00900601311004153 5565 122 55 0.450819672131148 0.00988319856244385
GO:CC GO:0005622 intracellular anatomical structure 0.0114520842177623 14790 84 78 0.928571428571429 0.00527383367139959
GO:CC GO:0005737 cytoplasm 0.0114520842177623 11911 50 43 0.86 0.0036101083032491
GO:CC GO:0005654 nucleoplasm 0.0114520842177623 4102 117 42 0.358974358974359 0.0102389078498294
GO:CC GO:0043231 intracellular membrane-bounded organelle 0.013678367630842 11296 55 45 0.818181818181818 0.00398371104815864
GO:CC GO:0031981 nuclear lumen 0.0138246148495939 4444 117 44 0.376068376068376 0.0099009900990099
GO:CC GO:0098562 cytoplasmic side of membrane 0.0139527647018869 194 35 4 0.114285714285714 0.0206185567010309
GO:CC GO:0005681 spliceosomal complex 0.0173439591922176 191 17 3 0.176470588235294 0.0157068062827225
GO:CC GO:0043227 membrane-bounded organelle 0.018129859123393 12858 51 45 0.882352941176471 0.00349976668222119
GO:CC GO:0070062 extracellular exosome 0.0186051760442735 2176 49 14 0.285714285714286 0.00643382352941176
GO:CC GO:0043229 intracellular organelle 0.0186051760442735 12491 51 44 0.862745098039216 0.00352253622608278
GO:CC GO:0043226 organelle 0.0190910544588196 14008 51 47 0.92156862745098 0.00335522558537978
GO:CC GO:1903561 extracellular vesicle 0.022327249444762 2261 49 14 0.285714285714286 0.00619195046439629
GO:CC GO:0005791 rough endoplasmic reticulum 0.022327249444762 86 49 3 0.0612244897959184 0.0348837209302326
GO:CC GO:0043230 extracellular organelle 0.022327249444762 2263 49 14 0.285714285714286 0.00618647812638091
GO:CC GO:0005813 centrosome 0.0255767702795387 619 40 6 0.15 0.00969305331179321
GO:CC GO:0016591 RNA polymerase II, holoenzyme 0.0332196968234859 92 117 4 0.0341880341880342 0.0434782608695652
GO:CC GO:0009898 cytoplasmic side of plasma membrane 0.0332196968234859 168 31 3 0.0967741935483871 0.0178571428571429
GO:CC GO:1902494 catalytic complex 0.0377900207075922 1441 57 11 0.192982456140351 0.00763358778625954
GO:MF GO:0008135 translation factor activity, RNA binding 0.0202273877184923 99 136 6 0.0441176470588235 0.0606060606060606
GO:MF GO:0005515 protein binding 0.0230581017727432 14767 134 122 0.91044776119403 0.00826166452224555
GO:MF GO:0047485 protein N-terminus binding 0.0262202603470062 111 55 4 0.0727272727272727 0.036036036036036
GO:MF GO:0044877 protein-containing complex binding 0.0262202603470062 1287 63 13 0.206349206349206 0.0101010101010101
GO:MF GO:0051082 unfolded protein binding 0.0323022035781694 112 63 4 0.0634920634920635 0.0357142857142857
GO:MF GO:0052689 carboxylic ester hydrolase activity 0.0394773777973806 146 103 5 0.0485436893203883 0.0342465753424658
GO:MF GO:0003723 RNA binding 0.0394773777973806 1943 27 9 0.333333333333333 0.00463201235203294
GO:MF GO:0008134 transcription factor binding 0.0437721140726965 676 91 10 0.10989010989011 0.014792899408284
GO:MF GO:0140297 DNA-binding transcription factor binding 0.0470491366339929 391 132 9 0.0681818181818182 0.0230179028132992
GO:MF GO:0061135 endopeptidase regulator activity 0.0473287346562125 188 88 5 0.0568181818181818 0.0265957446808511
REAC REAC:R-HSA-167242 Abortive elongation of HIV-1 transcript in the absence of Tat 0.00772815842662631 21 113 4 0.0353982300884956 0.19047619047619
REAC REAC:R-HSA-72695 Formation of the ternary complex, and subsequently, the 43S complex 0.00772815842662631 52 14 3 0.214285714285714 0.0576923076923077
REAC REAC:R-HSA-72702 Ribosomal scanning and start codon recognition 0.00772815842662631 59 14 3 0.214285714285714 0.0508474576271186
REAC REAC:R-HSA-72649 Translation initiation complex formation 0.00772815842662631 59 14 3 0.214285714285714 0.0508474576271186
REAC REAC:R-HSA-72662 Activation of the mRNA upon binding of the cap-binding complex and eIFs, and subsequent binding to 43S 0.00772815842662631 60 14 3 0.214285714285714 0.05
REAC REAC:R-HSA-113418 Formation of the Early Elongation Complex 0.0162318265179023 31 113 4 0.0353982300884956 0.129032258064516
REAC REAC:R-HSA-167158 Formation of the HIV-1 Early Elongation Complex 0.0162318265179023 31 113 4 0.0353982300884956 0.129032258064516
REAC REAC:R-HSA-72165 mRNA Splicing - Minor Pathway 0.0162318265179023 51 113 5 0.0442477876106195 0.0980392156862745
REAC REAC:R-HSA-162599 Late Phase of HIV Life Cycle 0.0228872133459108 134 113 7 0.0619469026548673 0.0522388059701493
REAC REAC:R-HSA-72163 mRNA Splicing - Major Pathway 0.0265697835067863 178 116 8 0.0689655172413793 0.0449438202247191
REAC REAC:R-HSA-8851708 Signaling by FGFR2 IIIa TM 0.0287096000304445 18 113 3 0.0265486725663717 0.166666666666667
REAC REAC:R-HSA-72172 mRNA Splicing 0.0300637508223935 186 116 8 0.0689655172413793 0.043010752688172
REAC REAC:R-HSA-162587 HIV Life Cycle 0.0300637508223935 147 113 7 0.0619469026548673 0.0476190476190476
REAC REAC:R-HSA-167169 HIV Transcription Elongation 0.0302116728072871 44 113 4 0.0353982300884956 0.0909090909090909
REAC REAC:R-HSA-72203 Processing of Capped Intron-Containing Pre-mRNA 0.0302116728072871 235 116 9 0.0775862068965517 0.0382978723404255
REAC REAC:R-HSA-167246 Tat-mediated elongation of the HIV-1 transcript 0.0302116728072871 44 113 4 0.0353982300884956 0.0909090909090909
REAC REAC:R-HSA-167200 Formation of HIV-1 elongation complex containing HIV-1 Tat 0.0302116728072871 44 113 4 0.0353982300884956 0.0909090909090909
REAC REAC:R-HSA-167152 Formation of HIV elongation complex in the absence of HIV Tat 0.032977408425588 46 113 4 0.0353982300884956 0.0869565217391304
REAC REAC:R-HSA-8953854 Metabolism of RNA 0.0384677044662613 658 124 17 0.137096774193548 0.0258358662613982
REAC REAC:R-HSA-6803529 FGFR2 alternative splicing 0.0459753866541627 25 113 3 0.0265486725663717 0.12
REAC REAC:R-HSA-109606 Intrinsic Pathway for Apoptosis 0.0495739975107866 52 117 4 0.0341880341880342 0.0769230769230769
TF TF:M09935_1 Factor: GABP-alpha; motif: NNNRCCGGAAGTGN; match class: 1 0.000102867686544093 1047 17 9 0.529411764705882 0.00859598853868195
TF TF:M09905_1 Factor: SAP-1; motif: NNCCGGAAGTGN; match class: 1 0.000102867686544093 2989 17 13 0.764705882352941 0.00434928069588491
TF TF:M09901_1 Factor: nerf; motif: NNNCCGGAAGTGN; match class: 1 0.000102867686544093 1363 18 10 0.555555555555556 0.00733675715333822
TF TF:M08913_1 Factor: FLI-1; motif: NAYTTCCGGT; match class: 1 0.000102867686544093 3055 17 13 0.764705882352941 0.00425531914893617
TF TF:M02055_1 Factor: ESE-1; motif: NSMGGAARTN; match class: 1 0.000303004895807234 2176 123 34 0.276422764227642 0.015625
TF TF:M01214_1 Factor: ESE-1; motif: NSMGGAARTN; match class: 1 0.000303004895807234 2176 123 34 0.276422764227642 0.015625
TF TF:M09900_1 Factor: Elf-1; motif: NNANCCGGAAGTGS; match class: 1 0.000345555529834695 1158 94 20 0.212765957446809 0.0172711571675302
TF TF:M11425_1 Factor: PEA3; motif: NACCGGAAGTN; match class: 1 0.000345555529834695 2330 17 11 0.647058823529412 0.00472103004291845
TF TF:M01258 Factor: GABP; motif: CACTTCCGGNNN 0.000356094818218424 2838 121 39 0.322314049586777 0.0137420718816068
TF TF:M09605_1 Factor: Elf-1; motif: NAANCMGGAAGTGN; match class: 1 0.000403134280864952 1306 86 20 0.232558139534884 0.0153139356814701
TF TF:M02074 Factor: GABPalpha; motif: RCCGGAWRYN 0.000507423964574507 4607 117 51 0.435897435897436 0.011070110701107
TF TF:M11439 Factor: Net; motif: NRCCGGAAGTN 0.000507423964574507 2568 121 36 0.297520661157025 0.014018691588785
TF TF:M07209 Factor: ELK4; motif: NCRCTTCCGGN 0.000507423964574507 1118 121 22 0.181818181818182 0.0196779964221825
TF TF:M11437 Factor: SAP-1; motif: NRCCGGAWGYN 0.000507423964574507 2788 121 38 0.31404958677686 0.0136298421807747
TF TF:M11432_1 Factor: Elk-1; motif: NACMGGAAGTN; match class: 1 0.000546057001728113 1525 17 9 0.529411764705882 0.0059016393442623
TF TF:M02102 Factor: NRF-1; motif: YGCGCMTGCGC 0.000546057001728113 2020 122 31 0.254098360655738 0.0153465346534653
TF TF:M03832 Factor: Net; motif: CACTTCCKGK 0.000573131539702578 929 114 19 0.166666666666667 0.0204520990312164
TF TF:M09904_1 Factor: Elk-1; motif: RCCGGAAGTGN; match class: 1 0.000736791476977365 2743 17 11 0.647058823529412 0.004010207801677
TF TF:M02053_1 Factor: ELF1; motif: NCCGGAARTN; match class: 1 0.000767234531561876 1559 121 26 0.214876033057851 0.0166773572803079
TF TF:M03981 Factor: ETV3; motif: ACCGGAAGTN 0.000852993879896318 2327 121 33 0.272727272727273 0.0141813493768801
TF TF:M11413 Factor: ER71; motif: NACCGGAARTN 0.000874365543857389 2111 121 31 0.256198347107438 0.01468498342018
TF TF:M11433_1 Factor: Elk-1; motif: NRCCGGAAGTN; match class: 1 0.000990292562262319 2261 17 10 0.588235294117647 0.00442282176028306
TF TF:M04869_1 Factor: Egr-1; motif: GCGCATGCG; match class: 1 0.000990292562262319 10253 49 41 0.836734693877551 0.00399882961084561
TF TF:M02066_1 Factor: PEA3; motif: RCCGGAAGYN; match class: 1 0.000995218740360525 2283 17 10 0.588235294117647 0.00438020148926851
TF TF:M11392_1 Factor: Erg; motif: NACCGGAARYN; match class: 1 0.000995218740360525 3233 24 14 0.583333333333333 0.00433034333436437
TF TF:M01752_1 Factor: ERG; motif: ACCGGAART; match class: 1 0.00114748182067273 3705 17 12 0.705882352941177 0.00323886639676113
TF TF:M00025_1 Factor: Elk-1; motif: NNNNCCGGAARTNN; match class: 1 0.00143677386742018 4639 17 13 0.764705882352941 0.00280232808794999
TF TF:M09606_1 Factor: nerf; motif: NRRNSCGGAAGNRNNNN; match class: 1 0.00144824069410914 1704 18 9 0.5 0.00528169014084507
TF TF:M01078_1 Factor: c-Ets-1; motif: NNNRCCGGAWRYNNNN; match class: 1 0.00157252949107511 2448 17 10 0.588235294117647 0.00408496732026144
TF TF:M08423 Factor: TEF-3:ER81; motif: ACCGGAAATRCC 0.00157252949107511 3845 123 45 0.365853658536585 0.011703511053316
TF TF:M03982_1 Factor: ETV4; motif: ACCGGAAGTN; match class: 1 0.00172590027483144 2009 24 11 0.458333333333333 0.00547536087605774
TF TF:M11434_1 Factor: Elk-1; motif: NRSCGGAAGNN; match class: 1 0.00172590027483144 2935 24 13 0.541666666666667 0.00442930153321976
TF TF:M02054 Factor: ELF2; motif: CCCGGAARYN 0.0018196733060673 3066 121 38 0.31404958677686 0.0123939986953686
TF TF:M11451_1 Factor: Elf-1; motif: NANCCGGAAGTN; match class: 1 0.00205381373357188 2112 117 29 0.247863247863248 0.0137310606060606
TF TF:M11415 Factor: GABP-alpha; motif: NRCCGGAAGTN 0.00205381373357188 3257 121 39 0.322314049586777 0.0119742093951489
TF TF:M11447_1 Factor: Elf-1; motif: NAMCCGGAAGTN; match class: 1 0.00205381373357188 2593 24 12 0.5 0.00462784419591207
TF TF:M04698 Factor: GABP-alpha; motif: CACTTCCGG 0.00205381373357188 3196 123 39 0.317073170731707 0.0122027534418023
TF TF:M07415_1 Factor: Elf-1; motif: AWCCCGGAAGTN; match class: 1 0.00205381373357188 2397 12 8 0.666666666666667 0.0033375052148519
TF TF:M02071_1 Factor: ETV7; motif: NCCGGAANNN; match class: 1 0.00205381373357188 4465 117 47 0.401709401709402 0.0105263157894737
TF TF:M10115_1 Factor: LRF; motif: NRGGGKCKY; match class: 1 0.00205381373357188 2326 34 14 0.411764705882353 0.0060189165950129
TF TF:M04714_1 Factor: Elf-1; motif: ACTTCCGGG; match class: 1 0.00205381373357188 2659 17 10 0.588235294117647 0.00376081233546446
TF TF:M02073_1 Factor: Fli-1; motif: ACCGGAAGYN; match class: 1 0.00205381373357188 1488 17 8 0.470588235294118 0.00537634408602151
TF TF:M11399_1 Factor: Fli-1; motif: NACCGGAWWTCCGGTY; match class: 1 0.00205381373357188 11513 36 33 0.916666666666667 0.00286632502388604
TF TF:M02052_1 Factor: EHF; motif: CSCGGAARTN; match class: 1 0.00205381373357188 4056 117 44 0.376068376068376 0.0108481262327416
TF TF:M08759_1 Factor: c-Ets-2; motif: NCCGGAAGTG; match class: 1 0.00205381373357188 2915 123 37 0.300813008130081 0.0126929674099485
TF TF:M11422_1 Factor: Erm; motif: NRCMGGAAGTN; match class: 1 0.00205381373357188 934 109 17 0.155963302752294 0.0182012847965739
TF TF:M11428_1 Factor: PEA3; motif: NACCGGAAGTN; match class: 1 0.00205381373357188 2146 117 29 0.247863247863248 0.0135135135135135
TF TF:M11396_1 Factor: Erg; motif: NACCGGAARTN; match class: 1 0.00205381373357188 4963 17 13 0.764705882352941 0.00261938343743703
TF TF:M11436_1 Factor: SAP-1; motif: NRNCGGAWRYN; match class: 1 0.00205381373357188 136 76 6 0.0789473684210526 0.0441176470588235
TF TF:M09913 Factor: ER81; motif: NNCCGGAAGYG 0.00205381373357188 2871 121 36 0.297520661157025 0.0125391849529781
TF TF:M02072 Factor: Pet-1; motif: ACCGGAWRTN 0.00205381373357188 2395 121 32 0.264462809917355 0.0133611691022965
TF TF:M03970 Factor: ELK1; motif: ACCGGAAGTN 0.00211598719526892 4782 129 53 0.410852713178295 0.0110832287745713
TF TF:M09607 Factor: SAP-1; motif: ACCGGAAGTNN 0.00211598719526892 4727 124 51 0.411290322580645 0.0107890839856146
TF TF:M02062_1 Factor: Erg; motif: ACCGGAAGTN; match class: 1 0.0022588438105844 2718 17 10 0.588235294117647 0.00367917586460633
TF TF:M03970_1 Factor: ELK1; motif: ACCGGAAGTN; match class: 1 0.00227775809361159 1097 17 7 0.411764705882353 0.00638103919781222
TF TF:M04694 Factor: NRF-1; motif: CNCTGCGCATGCGC 0.00240636465369203 1548 129 25 0.193798449612403 0.0161498708010336
TF TF:M02065_1 Factor: ER81; motif: RCCGGAARYN; match class: 1 0.0025524218935773 6749 117 62 0.52991452991453 0.00918654615498592
TF TF:M09935 Factor: GABP-alpha; motif: NNNRCCGGAAGTGN 0.00265125985507567 4420 123 48 0.390243902439024 0.0108597285067873
TF TF:M02067_1 Factor: ER71; motif: ACCGGAARYN; match class: 1 0.00277626632600869 1619 17 8 0.470588235294118 0.00494132180358246
TF TF:M02053 Factor: ELF1; motif: NCCGGAARTN 0.00318127385949064 6033 117 57 0.487179487179487 0.00944803580308304
TF TF:M01258_1 Factor: GABP; motif: CACTTCCGGNNN; match class: 1 0.00321078208148203 428 57 8 0.140350877192982 0.0186915887850467
TF TF:M07052 Factor: NRF-1; motif: GCGCMTGCGCN 0.00339225069167379 2130 122 29 0.237704918032787 0.0136150234741784
TF TF:M03990_1 Factor: GABPA; motif: ACCGGAAGTN; match class: 1 0.00353364629600589 1206 12 6 0.5 0.00497512437810945
TF TF:M11449_1 Factor: Elf-1; motif: NANCCGGAAGTN; match class: 1 0.00353364629600589 695 12 5 0.416666666666667 0.00719424460431655
TF TF:M09641_1 Factor: NRF-1; motif: SYGCGCMTGCGCRNNGSN; match class: 1 0.00376361313918507 991 122 18 0.147540983606557 0.0181634712411705
TF TF:M07206 Factor: E2F-1; motif: NGGGCGGGARV 0.00376361313918507 14575 58 55 0.948275862068966 0.00377358490566038
TF TF:M03988_1 Factor: FLI1; motif: ACCGGAARTN; match class: 1 0.00379692576975818 2950 17 10 0.588235294117647 0.00338983050847458
TF TF:M11414 Factor: GABP-alpha; motif: NACCGGAAGTN 0.00425926776097551 2907 121 35 0.289256198347107 0.0120399036807706
TF TF:M10785_1 Factor: hoxa9; motif: RTCGTWANNN; match class: 1 0.00425926776097551 1160 116 19 0.163793103448276 0.0163793103448276
TF TF:M02059_1 Factor: ELK-1; motif: ACCGGAAGTN; match class: 1 0.00432046852223266 3759 17 11 0.647058823529412 0.00292631018888002
TF TF:M02069_1 Factor: Erm; motif: ACCGGAAGTN; match class: 1 0.00432046852223266 1955 12 7 0.583333333333333 0.00358056265984655
TF TF:M09900 Factor: Elf-1; motif: NNANCCGGAAGTGS 0.00439589496536596 5219 129 55 0.426356589147287 0.0105384173213259
TF TF:M01109 Factor: SZF1-1; motif: CCAGGGTAWCAGCNG 0.00448241019331144 4253 23 14 0.608695652173913 0.00329179402774512
TF TF:M04823 Factor: E2F-4; motif: NNTTCCCGCCNN 0.00448241019331144 12747 54 48 0.888888888888889 0.00376559190397741
TF TF:M03983 Factor: ETV5; motif: NCCGGAWGYN 0.00460346191931385 3129 123 37 0.300813008130081 0.0118248641738575
TF TF:M09611 Factor: ER81; motif: NNNGRCMGGAAGYRNNNNNNNS 0.00460346191931385 2666 127 34 0.267716535433071 0.0127531882970743
TF TF:M03977_1 Factor: ETS1; motif: ACCGGAARYN; match class: 1 0.00460346191931385 4677 117 47 0.401709401709402 0.0100491768227496
TF TF:M02063_1 Factor: c-ets-1; motif: ACCGGAWGTN; match class: 1 0.00461701599266822 2396 17 9 0.529411764705882 0.00375626043405676
TF TF:M08757 Factor: nerf; motif: AAMCCGGAAGTN 0.00478782263935626 715 113 14 0.123893805309735 0.0195804195804196
TF TF:M11452_1 Factor: Elf-1; motif: NANGCGGAAGTR; match class: 1 0.00478782263935626 1696 18 8 0.444444444444444 0.00471698113207547
TF TF:M09913_1 Factor: ER81; motif: NNCCGGAAGYG; match class: 1 0.00478782263935626 420 11 4 0.363636363636364 0.00952380952380952
TF TF:M11421 Factor: ER81; motif: NACCGGAAGTN 0.00478995906890175 2341 121 30 0.247933884297521 0.0128150363092695
TF TF:M12232 Factor: c-Krox; motif: NCGACCACCN 0.00494345501901411 2982 97 30 0.309278350515464 0.0100603621730382
TF TF:M11420 Factor: ER81; motif: NACCGGAAGTN 0.00498774833662305 3210 121 37 0.305785123966942 0.0115264797507788
TF TF:M04869 Factor: Egr-1; motif: GCGCATGCG 0.00499991412363822 11232 49 41 0.836734693877551 0.0036502849002849
TF TF:M11601_1 Factor: TCF-1; motif: ACATCGRGRCGCTGW; match class: 1 0.00511608860955955 11053 51 42 0.823529411764706 0.00379987333755541
TF TF:M11402 Factor: Fli-1; motif: NACCGGAARTN 0.00535258708040957 3885 117 41 0.35042735042735 0.0105534105534106
TF TF:M00803 Factor: E2F; motif: GGCGSG 0.00544750209272829 13190 57 51 0.894736842105263 0.00386656557998484
TF TF:M11404_1 Factor: Fli-1; motif: NACCGGAARTN; match class: 1 0.00544750209272829 3171 17 10 0.588235294117647 0.00315357931251971
TF TF:M03969_1 Factor: ELF5; motif: ANSMGGAAGTN; match class: 1 0.00561310664037036 443 99 10 0.101010101010101 0.0225733634311512
TF TF:M11424_1 Factor: Erm; motif: NNSCGGAWGYN; match class: 1 0.00569339171176819 2835 98 29 0.295918367346939 0.0102292768959436
TF TF:M02056 Factor: ELF4; motif: NCCGGAARTN 0.00578104801596775 5332 117 51 0.435897435897436 0.0095648912228057
TF TF:M11400_1 Factor: Fli-1; motif: NACCGGAARTN; match class: 1 0.00585709480204347 4201 24 14 0.583333333333333 0.00333253987145918
TF TF:M08917 Factor: GABP-ALPHA; motif: RCCGGAARTNN 0.00585709480204347 2702 123 33 0.268292682926829 0.0122131754256107
TF TF:M08377_1 Factor: meis1:Elf-1; motif: NTGCCGGAAGTN; match class: 1 0.00585709480204347 5051 43 23 0.534883720930233 0.00455355375173233
TF TF:M03988 Factor: FLI1; motif: ACCGGAARTN 0.00585709480204347 8318 117 70 0.598290598290598 0.00841548449146429
TF TF:M11432 Factor: Elk-1; motif: NACMGGAAGTN 0.00585709480204347 6140 129 61 0.472868217054264 0.00993485342019544
TF TF:M11450_1 Factor: Elf-1; motif: NANSCGGAAGTR; match class: 1 0.00587694043404714 1315 18 7 0.388888888888889 0.00532319391634981
TF TF:M11422 Factor: Erm; motif: NRCMGGAAGTN 0.00587694043404714 4669 129 50 0.387596899224806 0.0107089312486614
TF TF:M08760 Factor: ETV7; motif: NNSCGGAAGTR 0.00587694043404714 2349 123 30 0.24390243902439 0.0127713920817369
TF TF:M11430_1 Factor: PEA3; motif: NACCGGAAGTN; match class: 1 0.00587694043404714 4902 17 12 0.705882352941177 0.00244798041615667
TF TF:M03975_1 Factor: ERG; motif: ACCGGAARTN; match class: 1 0.00587694043404714 4024 17 11 0.647058823529412 0.00273359840954274
TF TF:M00032_1 Factor: c-Ets-1(p54); motif: NCMGGAWGYN; match class: 1 0.00587694043404714 2161 121 28 0.231404958677686 0.012956964368348
TF TF:M02074_1 Factor: GABPalpha; motif: RCCGGAWRYN; match class: 1 0.00587694043404714 1005 65 12 0.184615384615385 0.0119402985074627
TF TF:M08451_1 Factor: Elk-1:HOXA1; motif: ACCGGAAGTAATTA; match class: 1 0.00587694043404714 2584 24 11 0.458333333333333 0.00425696594427245
TF TF:M02066 Factor: PEA3; motif: RCCGGAAGYN 0.00587694043404714 7045 117 62 0.52991452991453 0.00880056777856636
TF TF:M11419_1 Factor: ER81; motif: NNCCGGAWGYN; match class: 1 0.00635607209189872 1427 17 7 0.411764705882353 0.00490539593552908
TF TF:M10018 Factor: NRF-1; motif: CNSTGCGCATGCGCNNS 0.00636124283561788 1816 129 26 0.201550387596899 0.0143171806167401
TF TF:M11449 Factor: Elf-1; motif: NANCCGGAAGTN 0.00675536332343318 4305 35 18 0.514285714285714 0.00418118466898955
TF TF:M09892 Factor: E2F-1; motif: NNNNGGCGGGAARN 0.00675536332343318 13528 54 49 0.907407407407407 0.00362211709047901
TF TF:M09734 Factor: ZNF692; motif: SYNGGSCCCASCCNC 0.00686190356797254 11678 91 71 0.78021978021978 0.00607980818633328
TF TF:M03990 Factor: GABPA; motif: ACCGGAAGTN 0.00694133789511741 5258 117 50 0.427350427350427 0.00950931913275009
TF TF:M11425 Factor: PEA3; motif: NACCGGAAGTN 0.00707006780259667 7428 130 70 0.538461538461538 0.00942380183091007
TF TF:M07380 Factor: E2F-4; motif: NTTTCSCGCC 0.00751778231042904 13022 58 51 0.879310344827586 0.00391644908616188
TF TF:M03876_1 Factor: Kaiso; motif: GCMGGGRGCRGS; match class: 1 0.00752319926494744 9106 58 41 0.706896551724138 0.00450252580716011
TF TF:M08934 Factor: JUND; motif: NATGAGTCAT 0.00752319926494744 4329 12 9 0.75 0.00207900207900208
TF TF:M11401_1 Factor: Fli-1; motif: NACCGGATATCCGGTN; match class: 1 0.00752319926494744 11801 36 32 0.888888888888889 0.00271163460723667
TF TF:M01165 Factor: Elk-1; motif: RACCGGAAGTR 0.00784382335616018 7773 117 66 0.564102564102564 0.00849093014280201
TF TF:M10849 Factor: Cdx-2; motif: NRTCGTAANNNN 0.0079689653055504 11163 116 85 0.732758620689655 0.00761444056257279
TF TF:M03983_1 Factor: ETV5; motif: NCCGGAWGYN; match class: 1 0.0079689653055504 537 57 8 0.140350877192982 0.0148975791433892
TF TF:M01595_1 Factor: STAT3; motif: NNTTCCRGGAANNNNN; match class: 1 0.00819452000497667 2700 28 12 0.428571428571429 0.00444444444444444
TF TF:M11427_1 Factor: PEA3; motif: NACCGGAAGTN; match class: 1 0.00819452000497667 4606 123 47 0.382113821138211 0.0102040816326531
TF TF:M01752 Factor: ERG; motif: ACCGGAART 0.00852860248032583 9474 117 76 0.64957264957265 0.0080219548237281
TF TF:M11529_1 Factor: E2F-2; motif: GCGCGCGCNCS; match class: 1 0.00898412120810576 14473 139 120 0.863309352517986 0.00829130104332205
TF TF:M08566 Factor: ER71:Sox-20; motif: NCCGGAARYNNNNNACAAWRS 0.00898412120810576 35 61 3 0.0491803278688525 0.0857142857142857
TF TF:M03969 Factor: ELF5; motif: ANSMGGAAGTN 0.00898412120810576 3339 12 8 0.666666666666667 0.00239592692422881
TF TF:M01208_1 Factor: FLI-1; motif: CMGGAWGTSAN; match class: 1 0.00904349397145114 1286 63 13 0.206349206349206 0.0101088646967341
TF TF:M11603_1 Factor: TCF-1; motif: ACATCGRGRCGCTGW; match class: 1 0.00904349397145114 13184 54 48 0.888888888888889 0.00364077669902913
TF TF:M07052_1 Factor: NRF-1; motif: GCGCMTGCGCN; match class: 1 0.00910352105204443 734 122 14 0.114754098360656 0.0190735694822888
TF TF:M11442 Factor: Net; motif: NACCGGAAGTN 0.00926946379570828 2012 121 26 0.214876033057851 0.0129224652087475
TF TF:M11401 Factor: Fli-1; motif: NACCGGATATCCGGTN 0.00927184927281472 11952 36 32 0.888888888888889 0.00267737617135207
TF TF:M12139 Factor: Egr-1; motif: NMCRCCCMCNCNN 0.00927184927281472 3773 68 26 0.382352941176471 0.00689106811555791
TF TF:M11450 Factor: Elf-1; motif: NANSCGGAAGTR 0.0093653241351952 5601 27 17 0.62962962962963 0.00303517229066238
TF TF:M11533_1 Factor: E2F-1; motif: NTTTTGGCGCCAWWWN; match class: 1 0.00939450441169496 8705 50 35 0.7 0.00402067777139575
TF TF:M02273 Factor: NURR1; motif: AAGGTCAC 0.00978693754253074 7668 9 9 1 0.00117370892018779
TF TF:M03791 Factor: GABPalpha_GABPbeta; motif: CTTCCKGY 0.0100334117673073 2969 34 14 0.411764705882353 0.00471539238800943
TF TF:M11662 Factor: HSF2; motif: RGAANGTTCYRGAAN 0.0102562755642723 272 88 7 0.0795454545454545 0.0257352941176471
TF TF:M08662_1 Factor: AP-2gamma:HES-7; motif: NNCACGYGNNNNNNSCCNNNGGS; match class: 1 0.0104327085229597 220 77 6 0.0779220779220779 0.0272727272727273
TF TF:M04721_1 Factor: STAT1; motif: NTTCCNGGA; match class: 1 0.0106249869435805 2635 6 5 0.833333333333333 0.00189753320683112
TF TF:M03967_1 Factor: ELF3; motif: WACCCGGAAGTAN; match class: 1 0.0109011536669827 1972 33 11 0.333333333333333 0.00557809330628803
TF TF:M00333_1 Factor: ZF5; motif: NRNGNGCGCGCWN; match class: 1 0.0112226680542764 12401 77 63 0.818181818181818 0.00508023546488186
TF TF:M11832 Factor: ERR1; motif: NNSAAGGTCRN 0.0112550851392191 1763 8 5 0.625 0.00283607487237663
TF TF:M11825 Factor: SF-1; motif: NNCAAGGTCAN 0.0112550851392191 1760 8 5 0.625 0.00284090909090909
TF TF:M09968 Factor: KLF15; motif: RGGGMGGRGNNGGGGGNGG 0.0112550851392191 3157 60 21 0.35 0.00665188470066519
TF TF:M10018_1 Factor: NRF-1; motif: CNSTGCGCATGCGCNNS; match class: 1 0.0112550851392191 851 122 15 0.122950819672131 0.0176263219741481
TF TF:M10785 Factor: hoxa9; motif: RTCGTWANNN 0.0112550851392191 5632 124 54 0.435483870967742 0.00958806818181818
TF TF:M08964 Factor: NR1B1:RXR-ALPHA; motif: RRGGTCANNNNNRGGTCA 0.0113038843341733 7003 91 49 0.538461538461538 0.0069970012851635
TF TF:M03924_1 Factor: YY1; motif: NNCGCCATTNN; match class: 1 0.0113164854122922 3700 137 43 0.313868613138686 0.0116216216216216
TF TF:M02063 Factor: c-ets-1; motif: ACCGGAWGTN 0.0118976346653801 7600 117 64 0.547008547008547 0.00842105263157895
TF TF:M11656 Factor: HSF1; motif: RGAANRTTCYRGAAN 0.012085774047981 2033 78 19 0.243589743589744 0.00934579439252336
TF TF:M03966_1 Factor: ELF1; motif: AACCCGGAAGTR; match class: 1 0.012085774047981 1577 123 22 0.178861788617886 0.0139505389980977
TF TF:M09605 Factor: Elf-1; motif: NAANCMGGAAGTGN 0.0122438995879441 5778 130 57 0.438461538461538 0.009865005192108
TF TF:M11419 Factor: ER81; motif: NNCCGGAWGYN 0.0125334153950546 5699 129 56 0.434108527131783 0.00982628531321285
TF TF:M08377 Factor: meis1:Elf-1; motif: NTGCCGGAAGTN 0.0125334153950546 11275 115 84 0.730434782608696 0.00745011086474501
TF TF:M07206_1 Factor: E2F-1; motif: NGGGCGGGARV; match class: 1 0.0125334153950546 10849 58 45 0.775862068965517 0.00414784772790119
TF TF:M03821 Factor: ER-beta; motif: ANNSTGACCYRGNN 0.0125334153950546 6456 10 9 0.9 0.00139405204460967
TF TF:M02064_1 Factor: c-ets-2; motif: ACCGGAWRTN; match class: 1 0.0131377658534224 4592 17 11 0.647058823529412 0.00239547038327526
TF TF:M11535 Factor: E2F-4; motif: TTTTGGCGCCAWWN 0.0133033526488827 10884 55 43 0.781818181818182 0.00395075339948548
TF TF:M11437_1 Factor: SAP-1; motif: NRCCGGAWGYN; match class: 1 0.0133033526488827 456 57 7 0.12280701754386 0.0153508771929825
TF TF:M02054_1 Factor: ELF2; motif: CCCGGAARYN; match class: 1 0.0133033526488827 456 57 7 0.12280701754386 0.0153508771929825
TF TF:M02093 Factor: ERR1; motif: CAAGGTCAMNN 0.0133325426639032 1395 6 4 0.666666666666667 0.0028673835125448
TF TF:M11399 Factor: Fli-1; motif: NACCGGAWWTCCGGTY 0.0134316525712704 12977 36 33 0.916666666666667 0.00254296062264006
TF TF:M01660_1 Factor: GABP-alpha; motif: CTTCCK; match class: 1 0.0136824762417708 5133 18 12 0.666666666666667 0.00233781414377557
TF TF:M02067 Factor: ER71; motif: ACCGGAARYN 0.0137053709125401 5930 117 53 0.452991452991453 0.00893760539629005
TF TF:M09641 Factor: NRF-1; motif: SYGCGCMTGCGCRNNGSN 0.0140157621910621 3222 112 33 0.294642857142857 0.0102420856610801
TF TF:M03979_1 Factor: ETV1; motif: ACCGGAAGTN; match class: 1 0.0140226006342981 57 48 3 0.0625 0.0526315789473684
TF TF:M08913 Factor: FLI-1; motif: NAYTTCCGGT 0.0140646878225206 8322 117 68 0.581196581196581 0.00817111271329007
TF TF:M11434 Factor: Elk-1; motif: NRSCGGAAGNN 0.0140655843090496 8219 18 15 0.833333333333333 0.00182503954252342
TF TF:M00491_1 Factor: MAZR; motif: NSGGGGGGGGMCN; match class: 1 0.0142263354264523 368 94 8 0.0851063829787234 0.0217391304347826
TF TF:M09901 Factor: nerf; motif: NNNCCGGAAGTGN 0.0142263354264523 5352 34 19 0.558823529411765 0.00355007473841555
TF TF:M03975 Factor: ERG; motif: ACCGGAARTN 0.0142263354264523 10002 131 86 0.656488549618321 0.00859828034393121
TF TF:M02056_1 Factor: ELF4; motif: NCCGGAARTN; match class: 1 0.014709998889178 1291 123 19 0.154471544715447 0.0147172734314485
TF TF:M09905 Factor: SAP-1; motif: NNCCGGAAGTGN 0.014709998889178 8273 18 15 0.833333333333333 0.00181312703976792
TF TF:M00327_1 Factor: Pax-3; motif: NNNNNNCGTCACGSTYNNNNN; match class: 1 0.014709998889178 6888 117 59 0.504273504273504 0.00856562137049942
TF TF:M02069 Factor: Erm; motif: ACCGGAAGTN 0.014709998889178 6892 117 59 0.504273504273504 0.00856065002901915
TF TF:M02085_1 Factor: Bcl-6; motif: NTTYCTAGRA; match class: 1 0.0149249661178182 1072 71 12 0.169014084507042 0.0111940298507463
TF TF:M11658 Factor: HSF4; motif: RGAANNTTCYRGAAN 0.0151233317516279 400 88 8 0.0909090909090909 0.02
TF TF:M08873 Factor: DLX2; motif: AMSMCTGACKG 0.0163900550453096 7441 132 69 0.522727272727273 0.00927294718451821
TF TF:M09613_1 Factor: Fli-1; motif: RCMGGAAGYGNNN; match class: 1 0.0164622160284833 866 127 15 0.118110236220472 0.0173210161662818
TF TF:M02061_1 Factor: ERF; motif: ACCGGAARYN; match class: 1 0.0176390965372783 363 76 7 0.0921052631578947 0.0192837465564738
TF TF:M11442_1 Factor: Net; motif: NACCGGAAGTN; match class: 1 0.0176390965372783 227 57 5 0.087719298245614 0.0220264317180617
TF TF:M08451 Factor: Elk-1:HOXA1; motif: ACCGGAAGTAATTA 0.0176554363574319 8421 18 15 0.833333333333333 0.00178126113288208
TF TF:M03902 Factor: GLI2; motif: GCGACCACMCTR 0.0176554363574319 1567 96 18 0.1875 0.01148691767709
TF TF:M11452 Factor: Elf-1; motif: NANGCGGAAGTR 0.017761056696125 6276 18 13 0.722222222222222 0.00207138304652645
TF TF:M09963 Factor: JunB; motif: NNTGAGTCANN 0.017761056696125 905 32 7 0.21875 0.00773480662983425
TF TF:M11448_1 Factor: Elf-1; motif: NANGCGGAAGTN; match class: 1 0.018493068469602 2324 18 8 0.444444444444444 0.00344234079173838
TF TF:M04694_1 Factor: NRF-1; motif: CNCTGCGCATGCGC; match class: 1 0.0187924392359782 466 79 8 0.10126582278481 0.0171673819742489
TF TF:M04698_1 Factor: GABP-alpha; motif: CACTTCCGG; match class: 1 0.0189328118661642 576 24 5 0.208333333333333 0.00868055555555556
TF TF:M04059 Factor: NRF-1; motif: YGCGCATGCGCN 0.0189328118661642 1471 129 21 0.162790697674419 0.0142760027192386
TF TF:M00716_1 Factor: ZF5; motif: GSGCGCGR; match class: 1 0.0189848305293602 14106 54 49 0.907407407407407 0.00347369913511981
TF TF:M11455 Factor: ELFR; motif: NANSCGGAAGTN 0.0196622609711112 631 123 12 0.0975609756097561 0.0190174326465927
TF TF:M11404 Factor: Fli-1; motif: NACCGGAARTN 0.0199236156752283 8743 131 77 0.587786259541985 0.00880704563650921
TF TF:M11578_1 Factor: foxl2; motif: NACGTMAACAN; match class: 1 0.0201446024314078 960 118 15 0.127118644067797 0.015625
TF TF:M00652 Factor: NRF-1; motif: CGCATGCGCR 0.020171965697671 1376 129 20 0.155038759689922 0.0145348837209302
TF TF:M11415_1 Factor: GABP-alpha; motif: NRCCGGAAGTN; match class: 1 0.0203251220524316 546 86 9 0.104651162790698 0.0164835164835165
TF TF:M04863_1 Factor: TF3C-beta; motif: CCNGGAGGGCTTCCTGGAGGAG; match class: 1 0.0203735550604085 8573 49 33 0.673469387755102 0.00384929429604572
TF TF:M11528_1 Factor: E2F-2; motif: NTTTTGGCGCCAWWWN; match class: 1 0.0203735550604085 4778 50 23 0.46 0.00481372959397237
TF TF:M03971 Factor: ELK1; motif: NACTTCCGSCGGAAGYN 0.0203735550604085 11293 18 17 0.944444444444444 0.00150535730098291
TF TF:M09894_1 Factor: E2F-4; motif: SNGGGCGGGAANN; match class: 1 0.0204394257043278 13929 131 109 0.83206106870229 0.00782540024409505
TF TF:M11659 Factor: HSF4; motif: NGAANRTTCTAGAAN 0.0215635411726017 329 88 7 0.0795454545454545 0.0212765957446809
TF TF:M11829 Factor: LRH-1; motif: NTCAAGGTCAN 0.0217920468372283 2181 8 5 0.625 0.00229252636405319
TF TF:M11395_1 Factor: Erg; motif: NACCGGAWWTCCGGTN; match class: 1 0.0217920468372283 7963 35 24 0.685714285714286 0.00301393947004898
TF TF:M07402 Factor: ESRRA; motif: YCAAGGTCACN 0.0221508161266141 1698 6 4 0.666666666666667 0.00235571260306243
TF TF:M03876 Factor: Kaiso; motif: GCMGGGRGCRGS 0.0221508161266141 13622 58 51 0.879310344827586 0.00374394362061371
TF TF:M08867 Factor: AP2; motif: GCCYGSGGSN 0.0221508161266141 10054 58 42 0.724137931034483 0.0041774418142033
TF TF:M11826 Factor: LRH-1; motif: NTCAAGGTCRN 0.0222210731653306 2199 8 5 0.625 0.0022737608003638
TF TF:M08345_1 Factor: HOXB2:PEA3; motif: ACCGGAAATGRN; match class: 1 0.0224186730374153 2198 121 26 0.214876033057851 0.0118289353958144
TF TF:M10026 Factor: PATZ; motif: GGGGNGGGGGMKGGRRNGGNRN 0.022580509995408 8389 52 34 0.653846153846154 0.00405292645130528
TF TF:M02070_1 Factor: TEL1; motif: CNCGGAANNN; match class: 1 0.0229427939324505 4841 33 17 0.515151515151515 0.00351167114232597
TF TF:M11392 Factor: Erg; motif: NACCGGAARYN 0.0229688106453307 8690 18 15 0.833333333333333 0.00172612197928654
TF TF:M02111 Factor: NR1B2; motif: NTGACCY 0.0232763485856112 9671 77 52 0.675324675324675 0.00537690001034019
TF TF:M07103 Factor: JunB; motif: NRRTGASTCAK 0.0232763485856112 2383 27 10 0.37037037037037 0.00419639110365086
TF TF:M11397_1 Factor: Erg; motif: NACCGGATATCCGGTN; match class: 1 0.0232763485856112 11731 35 30 0.857142857142857 0.00255732674111329
TF TF:M11657 Factor: HSF1; motif: NGAANRTTCKAGAAN 0.0232763485856112 337 88 7 0.0795454545454545 0.0207715133531157
TF TF:M00032 Factor: c-Ets-1(p54); motif: NCMGGAWGYN 0.0233248897103043 7858 117 64 0.547008547008547 0.00814456604734029
TF TF:M11439_1 Factor: Net; motif: NRCCGGAAGTN; match class: 1 0.0236481592039605 382 57 6 0.105263157894737 0.0157068062827225
TF TF:M11448 Factor: Elf-1; motif: NANGCGGAAGTN 0.0240659406494015 7600 18 14 0.777777777777778 0.00184210526315789
TF TF:M07313 Factor: ATF-3; motif: SNTGACGYNATN 0.0243529787186877 2894 39 14 0.358974358974359 0.00483759502418798
TF TF:M03989 Factor: FLI1; motif: ACCGGAAATCCGGT 0.0245822080026781 10442 35 28 0.8 0.00268147864393794
TF TF:M02055 Factor: ESE-1; motif: NSMGGAARTN 0.0249534078510749 7559 117 62 0.52991452991453 0.00820214314062707
TF TF:M01214 Factor: ESE-1; motif: NSMGGAARTN 0.0249534078510749 7559 117 62 0.52991452991453 0.00820214314062707
TF TF:M08917_1 Factor: GABP-ALPHA; motif: RCCGGAARTNN; match class: 1 0.0251856272700058 389 57 6 0.105263157894737 0.0154241645244216
TF TF:M02062 Factor: Erg; motif: ACCGGAAGTN 0.0254166185806644 8056 117 65 0.555555555555556 0.00806852035749752
TF TF:M03966 Factor: ELF1; motif: AACCCGGAAGTR 0.0254166185806644 6610 18 13 0.722222222222222 0.00196671709531014
TF TF:M02073 Factor: Fli-1; motif: ACCGGAAGYN 0.0254166185806644 5839 117 51 0.435897435897436 0.00873437232402809
TF TF:M02070 Factor: TEL1; motif: CNCGGAANNN 0.025493336416479 10837 123 85 0.691056910569106 0.00784349912337363
TF TF:M02000 Factor: ERR3; motif: CAAGGTCA 0.0257592324000708 2320 8 5 0.625 0.0021551724137931
TF TF:M00727 Factor: SF-1; motif: TGACCTTG 0.0257592324000708 2320 8 5 0.625 0.0021551724137931
TF TF:M00740_1 Factor: Rb:E2F-1:DP-1; motif: TTTSGCGC; match class: 1 0.025863580177326 4583 129 46 0.356589147286822 0.0100370936068078
TF TF:M07323 Factor: IRF-4; motif: KRAAMNGAAANYN 0.025863580177326 938 34 7 0.205882352941176 0.00746268656716418
TF TF:M02071 Factor: ETV7; motif: NCCGGAANNN 0.025863580177326 10116 18 16 0.888888888888889 0.00158165282720443
TF TF:M01742 Factor: Zfp206; motif: TGCGCAKGCGC 0.0265827437920455 274 112 7 0.0625 0.0255474452554745
TF TF:M07092 Factor: Fra-2; motif: NRRTGASTCAB 0.0273389782361138 3156 12 7 0.583333333333333 0.00221799746514575
TF TF:M02059 Factor: ELK-1; motif: ACCGGAAGTN 0.0273710561082793 9423 117 73 0.623931623931624 0.00774700201634299
TF TF:M11986_1 Factor: NFATc2; motif: NTTTCCATNNATGGAAAN; match class: 1 0.0274009078349597 5796 138 58 0.420289855072464 0.0100069013112491
TF TF:M02057_1 Factor: Elf5; motif: CSMGGAARNN; match class: 1 0.0277211605780063 3538 4 4 1 0.00113058224985868
TF TF:M11981_1 Factor: NFATc1; motif: NTTTCCRTNNAYGGAAAN; match class: 1 0.0277211605780063 5744 39 21 0.538461538461538 0.00365598885793872
TF TF:M11393_1 Factor: Erg; motif: NACCGGATATCCGGTN; match class: 1 0.0277211605780063 13665 37 34 0.918918918918919 0.00248810830589096
TF TF:M11428 Factor: PEA3; motif: NACCGGAAGTN 0.0277211605780063 7186 130 65 0.5 0.00904536598942388
TF TF:M11435_1 Factor: Elk-1; motif: NNCCGGAAGTN; match class: 1 0.0281762669793714 5745 18 12 0.666666666666667 0.002088772845953
TF TF:M07380_1 Factor: E2F-4; motif: NTTTCSCGCC; match class: 1 0.0282740863214008 7965 57 35 0.614035087719298 0.00439422473320778
TF TF:M07483 Factor: CXXC1; motif: KNRNAMCGMWAAMNN 0.0285004438005208 1318 8 4 0.5 0.00303490136570561
TF TF:M04008 Factor: HSF1; motif: TTCTAGAAYNTTC 0.0285004438005208 358 88 7 0.0795454545454545 0.0195530726256983
TF TF:M10438_1 Factor: ZF5; motif: GGSGCGCGS; match class: 1 0.0285004438005208 14873 54 50 0.925925925925926 0.00336179654407315
TF TF:M09892_1 Factor: E2F-1; motif: NNNNGGCGGGAARN; match class: 1 0.0285004438005208 9162 58 39 0.672413793103448 0.00425671250818599
TF TF:M07397_1 Factor: ZBP89; motif: CCCCKCCCCCNN; match class: 1 0.0285004438005208 2951 99 27 0.272727272727273 0.00914944086750254
TF TF:M09607_1 Factor: SAP-1; motif: ACCGGAAGTNN; match class: 1 0.0285004438005208 977 123 15 0.121951219512195 0.015353121801433
TF TF:M04106_1 Factor: RUNX2; motif: NRACCGCAAACCGCAN; match class: 1 0.0285004438005208 8372 51 33 0.647058823529412 0.00394171046344959
TF TF:M03982 Factor: ETV4; motif: ACCGGAAGTN 0.0285004438005208 6826 117 57 0.487179487179487 0.00835042484617638
TF TF:M00025 Factor: Elk-1; motif: NNNNCCGGAARTNN 0.0290652744904757 10262 18 16 0.888888888888889 0.00155915026310661
TF TF:M11446 Factor: Elf-1; motif: RANSMGGAAGTR 0.0303031004367239 2915 86 24 0.27906976744186 0.00823327615780446
TF TF:M06863 Factor: ZNF789; motif: NGGTKAGGCGGW 0.0303031004367239 75 122 4 0.0327868852459016 0.0533333333333333
TF TF:M09606 Factor: nerf; motif: NRRNSCGGAAGNRNNNN 0.0310911618429487 6249 114 52 0.456140350877193 0.00832133141302608
TF TF:M11530_1 Factor: E2F-2; motif: NWTTTGGCGCCAWWNN; match class: 1 0.0311633098726807 13449 54 47 0.87037037037037 0.00349468361959997
TF TF:M11979_1 Factor: NFATc1; motif: NTTTCCRTNNAYGGAAAN; match class: 1 0.0318336191406529 8680 39 27 0.692307692307692 0.00311059907834101
TF TF:M00341_1 Factor: GABP; motif: VCCGGAAGNGCR; match class: 1 0.0318336191406529 2318 12 6 0.5 0.00258843830888697
TF TF:M11839 Factor: ERR3; motif: NNSAAGGTCAN 0.0319141804517904 1371 8 4 0.5 0.00291757840991977
TF TF:M09896 Factor: E2F-7; motif: GRGGCGGGAANNN 0.0319141804517904 9927 58 41 0.706896551724138 0.0041301500956986
TF TF:M08487_1 Factor: GCMa:Erg; motif: ATGCGGGCGGAARKG; match class: 1 0.0320360161222122 8790 131 76 0.580152671755725 0.00864618885096701
TF TF:M11397 Factor: Erg; motif: NACCGGATATCCGGTN 0.0320360161222122 12005 35 30 0.857142857142857 0.00249895876718034
TF TF:M00925 Factor: AP-1; motif: NTGACTCAN 0.0324829011446641 2554 27 10 0.37037037037037 0.00391542678151919
TF TF:M07392 Factor: Pitx3; motif: GGATTANNNNY 0.0324829011446641 331 49 5 0.102040816326531 0.0151057401812689
TF TF:M08418_1 Factor: TEF-3:Elk-1; motif: RMATWCCGGAWGT; match class: 1 0.0324829011446641 5247 15 10 0.666666666666667 0.00190585096245474
TF TF:M03551 Factor: JunB; motif: TGACTCAN 0.0331610657726287 4253 15 9 0.6 0.00211615330355044
TF TF:M11382_1 Factor: ESE-1; motif: NWTRCGGAWGCN; match class: 1 0.0331610657726287 4112 24 12 0.5 0.00291828793774319
TF TF:M08423_1 Factor: TEF-3:ER81; motif: ACCGGAAATRCC; match class: 1 0.0331610657726287 654 114 11 0.0964912280701754 0.0168195718654434
TF TF:M04010 Factor: HSF4; motif: TTCTAGAANNTTC 0.0331610657726287 185 88 5 0.0568181818181818 0.027027027027027
TF TF:M02280 Factor: AP1; motif: TGACTCA 0.0331610657726287 4255 15 9 0.6 0.00211515863689777
TF TF:M00199_1 Factor: AP-1; motif: NTGASTCAG; match class: 1 0.0331610657726287 4265 15 9 0.6 0.00211019929660023
TF TF:M11451 Factor: Elf-1; motif: NANCCGGAAGTN 0.0331610657726287 6886 18 13 0.722222222222222 0.00188788846935812
TF TF:M00803_1 Factor: E2F; motif: GGCGSG; match class: 1 0.033375955463222 10230 52 38 0.730769230769231 0.00371456500488759
TF TF:M08944 Factor: JUNB:C-JUN; motif: NATGACKCAT 0.034153000094894 5313 15 10 0.666666666666667 0.00188217579521927
TF TF:M00114_1 Factor: Tax/CREB; motif: GGGGGTTGACGYANA; match class: 1 0.0343101455308992 1564 23 7 0.304347826086957 0.00447570332480818
TF TF:M11981 Factor: NFATc1; motif: NTTTCCRTNNAYGGAAAN 0.0343101455308992 6351 39 22 0.564102564102564 0.00346402141395056
TF TF:M09896_1 Factor: E2F-7; motif: GRGGCGGGAANNN; match class: 1 0.0343101455308992 4525 95 35 0.368421052631579 0.00773480662983425
TF TF:M03976 Factor: ERG; motif: ACCGGAWATCCGGT 0.0343101455308992 12803 35 31 0.885714285714286 0.00242130750605327
TF TF:M11447 Factor: Elf-1; motif: NAMCCGGAAGTN 0.0343101455308992 7703 117 62 0.52991452991453 0.00804881215110996
TF TF:M01078 Factor: c-Ets-1; motif: NNNRCCGGAWRYNNNN 0.0343101455308992 7544 117 61 0.521367521367521 0.00808589607635207
TF TF:M12158 Factor: KLF15; motif: NCCMCGCCCMCN 0.0345243397440853 11088 92 66 0.717391304347826 0.00595238095238095
TF TF:M09904 Factor: Elk-1; motif: RCCGGAAGTGN 0.0345243397440853 8164 130 71 0.546153846153846 0.00869671729544341
TF TF:M02281_1 Factor: SP1; motif: CCCCKCCCCC; match class: 1 0.0345964363098579 2558 99 24 0.242424242424242 0.00938232994526974
TF TF:M10747 Factor: GSH2; motif: NTCRTTAN 0.0345964363098579 3019 124 32 0.258064516129032 0.0105995362702882
TF TF:M12165 Factor: BTEB2; motif: NCCACRCCCN 0.0345964363098579 4901 29 15 0.517241379310345 0.003060599877576
TF TF:M10874 Factor: alx3; motif: NKCRTTAN 0.0345964363098579 3019 124 32 0.258064516129032 0.0105995362702882
TF TF:M10936 Factor: CHX10; motif: NTCRTTAN 0.0345964363098579 3019 124 32 0.258064516129032 0.0105995362702882
TF TF:M04516 Factor: E2F-1; motif: TTTGGCGCCAAA 0.0345964363098579 11383 51 40 0.784313725490196 0.00351401212334183
TF TF:M10945 Factor: VSX1; motif: NTCRTTAN 0.0345964363098579 3019 124 32 0.258064516129032 0.0105995362702882
TF TF:M09924 Factor: c-Fos; motif: NTGAGTCAN 0.0345964363098579 2431 12 6 0.5 0.00246812011517894
TF TF:M12313_1 Factor: ZNF460; motif: NNACNCCCCCCNN; match class: 1 0.0345964363098579 2203 95 21 0.221052631578947 0.00953245574216977
TF TF:M08759 Factor: c-Ets-2; motif: NCCGGAAGTG 0.0345964363098579 8319 130 72 0.553846153846154 0.00865488640461594
TF TF:M11533 Factor: E2F-1; motif: NTTTTGGCGCCAWWWN 0.0345964363098579 13105 54 46 0.851851851851852 0.00351011064479206
TF TF:M02068 Factor: etv3; motif: ACCGGAAGYN 0.0345964363098579 3443 114 33 0.289473684210526 0.00958466453674121
TF TF:M00646_1 Factor: LF-A1; motif: GGGSTCWR; match class: 1 0.0345964363098579 6320 37 21 0.567567567567568 0.00332278481012658
TF TF:M04721 Factor: STAT1; motif: NTTCCNGGA 0.0345964363098579 7847 10 9 0.9 0.00114693513444629
TF TF:M10563 Factor: Msx-1; motif: NTCRTTAN 0.0345964363098579 3019 124 32 0.258064516129032 0.0105995362702882
TF TF:M08441 Factor: AP-2gamma:Elk-1; motif: NGCCKNRGGSGRCGGAAGTG 0.0345964363098579 16345 104 97 0.932692307692308 0.00593453655552157
TF TF:M10942 Factor: VSX1; motif: NTCRTTAN 0.0345964363098579 3019 124 32 0.258064516129032 0.0105995362702882
TF TF:M10939 Factor: CHX10; motif: NTCRTTAN 0.0345964363098579 3019 124 32 0.258064516129032 0.0105995362702882
TF TF:M09616 Factor: Fra-2; motif: RTGACTCANNN 0.0348076900866945 4760 19 11 0.578947368421053 0.0023109243697479
TF TF:M10106 Factor: VDR; motif: NRGGTCANNGRGKTCA 0.0349835031665205 6955 24 16 0.666666666666667 0.00230050323508267
TF TF:M10438 Factor: ZF5; motif: GGSGCGCGS 0.0349835031665205 16228 132 121 0.916666666666667 0.0074562484594528
TF TF:M11421_1 Factor: ER81; motif: NACCGGAAGTN; match class: 1 0.0349835031665205 299 57 5 0.087719298245614 0.0167224080267559
TF TF:M11531 Factor: E2F-2; motif: GCGCGCGCGYW 0.0359720526852609 13270 84 69 0.821428571428571 0.00519969856819895
TF TF:M11986 Factor: NFATc2; motif: NTTTCCATNNATGGAAAN 0.0360432752240918 6055 138 59 0.427536231884058 0.0097440132122213
TF TF:M03967 Factor: ELF3; motif: WACCCGGAAGTAN 0.0360432752240918 7610 130 67 0.515384615384615 0.0088042049934297
TF TF:M04059_1 Factor: NRF-1; motif: YGCGCATGCGCN; match class: 1 0.0360432752240918 1033 122 15 0.122950819672131 0.0145208131655373
TF TF:M08313_1 Factor: GCMa:PEA3; motif: ATRCGGGCGGAAGTR; match class: 1 0.0360432752240918 9721 63 43 0.682539682539683 0.00442341322909166
TF TF:M01973 Factor: PLAG1; motif: CCCCCKWNNNGGSCCC 0.0361093590241279 6167 50 26 0.52 0.00421598832495541
TF TF:M04516_1 Factor: E2F-1; motif: TTTGGCGCCAAA; match class: 1 0.0361093590241279 10227 54 39 0.722222222222222 0.003813435024934
TF TF:M11979 Factor: NFATc1; motif: NTTTCCRTNNAYGGAAAN 0.0361093590241279 8844 39 27 0.692307692307692 0.00305291723202171
TF TF:M08920 Factor: JUNB:FOSB; motif: NRTGASTCAT 0.036359045947717 3151 27 11 0.407407407407407 0.00349095525230086
TF TF:M00191_1 Factor: ER; motif: NNARGNCANNNTGACCYNN; match class: 1 0.0364283813320548 769 7 3 0.428571428571429 0.00390117035110533
TF TF:M02052 Factor: EHF; motif: CSCGGAARTN 0.0364283813320548 10107 117 76 0.64957264957265 0.00751954091223904
TF TF:M07209_1 Factor: ELK4; motif: NCRCTTCCGGN; match class: 1 0.0364283813320548 84 57 3 0.0526315789473684 0.0357142857142857
TF TF:M02068_1 Factor: etv3; motif: ACCGGAAGYN; match class: 1 0.0364619476815761 613 57 7 0.12280701754386 0.0114192495921697
TF TF:M00983_1 Factor: MAF; motif: NGCTGAGTCAN; match class: 1 0.0364619476815761 1157 132 17 0.128787878787879 0.0146931719965428
TF TF:M01208 Factor: FLI-1; motif: CMGGAWGTSAN 0.0368603463418603 6232 132 58 0.439393939393939 0.00930680359435173
TF TF:M09833 Factor: RXRALPHA; motif: CNNTGRCCTYTNN 0.0369419545932839 5363 121 48 0.396694214876033 0.00895021443222077
TF TF:M10530_1 Factor: sp4; motif: NNNGCYCCGCCCCCY; match class: 1 0.0372244051558983 3780 51 19 0.372549019607843 0.00502645502645503
TF TF:M07100 Factor: HSF1; motif: NTTCTRGAANNTTCY 0.0372244051558983 3350 78 24 0.307692307692308 0.00716417910447761
TF TF:M08968 Factor: RXR-ALPHA; motif: RAGGTCA 0.0376613849268358 5242 9 7 0.777777777777778 0.00133536818008394
TF TF:M08963 Factor: NR1B1; motif: RAGGTCA 0.0376613849268358 5242 9 7 0.777777777777778 0.00133536818008394
TF TF:M03542 Factor: COUP-TF1; motif: TGACCTY 0.0376613849268358 5242 9 7 0.777777777777778 0.00133536818008394
TF TF:M07261 Factor: LKLF; motif: GGGGTGGKSN 0.0382612039022107 9774 75 50 0.666666666666667 0.00511561285041948
TF TF:M11406 Factor: Pet-1; motif: NACCGGAAGTN 0.0382612039022107 1301 129 18 0.13953488372093 0.0138355111452729
TF TF:M04515 Factor: E2F-1; motif: WWTGGCGCCAAA 0.038321196924196 13334 51 44 0.862745098039216 0.00329983500824959
TF TF:M07454 Factor: Gli1; motif: TGGGTGGTCN 0.038321196924196 2038 19 7 0.368421052631579 0.00343473994111874
TF TF:M04106 Factor: RUNX2; motif: NRACCGCAAACCGCAN 0.0386594318507196 13833 51 45 0.882352941176471 0.00325309043591412
TF TF:M04456 Factor: ESRRA; motif: NTCAAGGTCAN 0.0386594318507196 1559 8 4 0.5 0.00256574727389352
TF TF:M01167_1 Factor: SAP-1a; motif: NACCGGAAGTV; match class: 1 0.0386594318507196 187 57 4 0.0701754385964912 0.0213903743315508
TF TF:M04714 Factor: Elf-1; motif: ACTTCCGGG 0.0386594318507196 7798 117 62 0.52991452991453 0.0079507566042575
TF TF:M00665 Factor: Sp3; motif: ASMCTTGGGSRGGG 0.0386594318507196 7729 58 34 0.586206896551724 0.00439901669038685
TF TF:M11845_1 Factor: ER-alpha; motif: NAGGTCANSNTGACCYN; match class: 1 0.0389107930387006 1742 22 7 0.318181818181818 0.00401836969001148
TF TF:M03860 Factor: USF2; motif: NNNCCACGTGACN 0.0389699581331938 3576 129 37 0.286821705426357 0.0103467561521253
TF TF:M11529 Factor: E2F-2; motif: GCGCGCGCNCS 0.0389854763665272 16263 139 127 0.913669064748201 0.00780913730554018
TF TF:M03821_1 Factor: ER-beta; motif: ANNSTGACCYRGNN; match class: 1 0.039127855653913 1368 9 4 0.444444444444444 0.00292397660818713
TF TF:M11460 Factor: nerf; motif: NANSCGGAAGTN 0.039127855653913 736 123 12 0.0975609756097561 0.016304347826087
TF TF:M10079 Factor: STAT1; motif: NCCNTTTCCNGGAAANCNC 0.0395461122030656 2284 6 4 0.666666666666667 0.00175131348511384
TF TF:M08571_1 Factor: Erm:E2A; motif: CASGTGNNNCGGAAGNN; match class: 1 0.0397071603121735 4425 78 29 0.371794871794872 0.00655367231638418
TF TF:M07289_1 Factor: GKLF; motif: NNNRGGNGNGGSN; match class: 1 0.0400158365275184 10555 61 44 0.721311475409836 0.00416864045476078
TF TF:M07367 Factor: Slug; motif: SSSNNNKCACCTGN 0.0408716383922254 1680 4 3 0.75 0.00178571428571429
TF TF:M02072_1 Factor: Pet-1; motif: ACCGGAWRTN; match class: 1 0.0420352926859624 323 57 5 0.087719298245614 0.0154798761609907
TF TF:M00737 Factor: E2F-1:DP-2; motif: TTTSSCGC 0.042172836660655 8771 100 59 0.59 0.00672671303158135
TF TF:M08227 Factor: Elk-1:PDEF; motif: NCMGGAMGGANATCCGGN 0.0424719925587544 8419 122 68 0.557377049180328 0.00807696876113553
TF TF:M08526_1 Factor: E2F-3:HES-7; motif: NNNSGCGCSNNNNNCRCGYGNN; match class: 1 0.0424719925587544 14997 58 53 0.913793103448276 0.00353404014136161
TF TF:M09613 Factor: Fli-1; motif: RCMGGAAGYGNNN 0.0424719925587544 5169 136 51 0.375 0.00986651189785258
TF TF:M00678 Factor: Tel-2; motif: YTACTTCCTG 0.0424885598243952 5292 130 50 0.384615384615385 0.00944822373393802
TF TF:M08760_1 Factor: ETV7; motif: NNSCGGAAGTR; match class: 1 0.0428234317853705 326 57 5 0.087719298245614 0.0153374233128834
TF TF:M11393 Factor: Erg; motif: NACCGGATATCCGGTN 0.0428767258480039 14105 37 34 0.918918918918919 0.00241049273307338
TF TF:M11433 Factor: Elk-1; motif: NRCCGGAAGTN 0.0428767258480039 7679 117 61 0.521367521367521 0.00794374267482745
TF TF:M01036 Factor: COUPTF; motif: NNNNNTGACCYTTGNMCNYNGMN 0.0430887788358551 3807 27 12 0.444444444444444 0.00315208825847124
TF TF:M00738_1 Factor: E2F-4:DP-1; motif: TTTSGCGC; match class: 1 0.0434422746728012 3999 129 40 0.310077519379845 0.0100025006251563
TF TF:M03981_1 Factor: ETV3; motif: ACCGGAAGTN; match class: 1 0.0438597727296865 329 57 5 0.087719298245614 0.0151975683890578
TF TF:M10115 Factor: LRF; motif: NRGGGKCKY 0.0438597727296865 7623 98 52 0.530612244897959 0.00682146136691591
TF TF:M11655 Factor: HSF1; motif: NGAANGTTCKRGAAN 0.0442622582276979 1207 88 13 0.147727272727273 0.0107705053852527
TF TF:M07232 Factor: TP53; motif: RCATGYCCAGACATG 0.044822338519398 2606 135 30 0.222222222222222 0.0115118956254797
TF TF:M09631 Factor: JunB; motif: NNNTGAGTCAY 0.044822338519398 1915 32 9 0.28125 0.00469973890339426
TF TF:M10477_1 Factor: ZNF436; motif: TCCTCCAGGAAGCCY; match class: 1 0.044822338519398 8681 133 75 0.56390977443609 0.00863955765464808
TF TF:M11835 Factor: ERR1; motif: NNCAAGGTCAN 0.044822338519398 1664 8 4 0.5 0.00240384615384615
TF TF:M04723_1 Factor: Thap1; motif: SCGCCATSTTKGNTNMGGGCARNN; match class: 1 0.0454289144688251 5283 137 52 0.37956204379562 0.00984289229604391
TF TF:M11420_1 Factor: ER81; motif: NACCGGAAGTN; match class: 1 0.0455191248130913 494 117 9 0.0769230769230769 0.0182186234817814
TF TF:M09664_1 Factor: STAT3; motif: NTTCCYGGAAN; match class: 1 0.0465019341062217 1875 27 8 0.296296296296296 0.00426666666666667
TF TF:M11838 Factor: ERR3; motif: NNSAAGGTCRN 0.0465019341062217 1071 6 3 0.5 0.00280112044817927
TF TF:M11407 Factor: Pet-1; motif: NACCGGAAGTN 0.0465019341062217 772 121 12 0.0991735537190083 0.0155440414507772
TF TF:M07084 Factor: E2F-4; motif: NGGCGGGAARN 0.0465019341062217 10834 131 88 0.67175572519084 0.00812257707218017
TF TF:M03987 Factor: FEV; motif: ACCGGAAGTN 0.0465127057552286 1318 121 17 0.140495867768595 0.0128983308042489
TF TF:M06463 Factor: ZNF595; motif: NGKGGCGGCMGM 0.0477645599143059 113 50 3 0.06 0.0265486725663717
TF TF:M00333 Factor: ZF5; motif: NRNGNGCGCGCWN 0.0477645599143059 15072 58 53 0.913793103448276 0.00351645435244161
TF TF:M10683 Factor: HOXB7; motif: GTCRTTAN 0.0477645599143059 1643 132 21 0.159090909090909 0.0127814972611077
TF TF:M11218 Factor: CREB1; motif: NRTGAYGCGTN 0.0477645599143059 8461 112 63 0.5625 0.00744592837726037
TF TF:M09887 Factor: CREB1; motif: NRRTGACGTMA 0.0477645599143059 5419 107 43 0.401869158878505 0.00793504336593467
TF TF:M08824 Factor: NET; motif: CMGGAARTR 0.0477645599143059 1028 129 15 0.116279069767442 0.014591439688716
TF TF:M09739 Factor: ZGPAT; motif: GRGGCWGNGGNG 0.0478936802375585 8226 50 31 0.62 0.0037685387794797
TF TF:M11841 Factor: ERR3; motif: NNSAAGGTCAN 0.0478936802375585 784 8 3 0.375 0.0038265306122449
TF TF:M11576_1 Factor: BF-1; motif: NACGYMAACAN; match class: 1 0.0478936802375585 87 135 4 0.0296296296296296 0.0459770114942529
TF TF:M11845 Factor: ER-alpha; motif: NAGGTCANSNTGACCYN 0.0478936802375585 3780 12 7 0.583333333333333 0.00185185185185185
TF TF:M03846 Factor: SMAD5; motif: GSGGCAGM 0.0480017342022317 8552 101 58 0.574257425742574 0.00678203928905519
TF TF:M00915 Factor: AP-2; motif: SNNNCCNCAGGCN 0.0482122228590982 9612 63 42 0.666666666666667 0.00436953807740325
TF TF:M09894 Factor: E2F-4; motif: SNGGGCGGGAANN 0.048314894035076 16194 133 121 0.909774436090226 0.00747190317401507
TF TF:M11402_1 Factor: Fli-1; motif: NACCGGAARTN; match class: 1 0.0485140981718103 601 117 10 0.0854700854700855 0.0166389351081531
TF TF:M08877 Factor: EGR3; motif: NCMCRCCCACTNMN 0.0485761015414179 6099 52 26 0.5 0.00426299393343171
TF TF:M11395 Factor: Erg; motif: NACCGGAWWTCCGGTN 0.0485761015414179 8715 35 24 0.685714285714286 0.00275387263339071
TF TF:M00986 Factor: Churchill; motif: CGGGNN 0.048603878443277 14197 58 51 0.879310344827586 0.00359230823413397
TF TF:M11526 Factor: E2F-3; motif: NTTTTGGCGCCAAAAN 0.048603878443277 7178 54 30 0.555555555555556 0.00417943716912789
TF TF:M08418 Factor: TEF-3:Elk-1; motif: RMATWCCGGAWGT 0.048603878443277 11758 24 21 0.875 0.00178601803027726
TF TF:M00051 Factor: NF-kappaB; motif: GGGGATYCCC 0.0488932490106486 6413 62 31 0.5 0.00483393107749883
TF TF:M11454 Factor: ELFR; motif: NANGMGGAAGTN 0.0489843607139829 1072 137 16 0.116788321167883 0.0149253731343284
TF TF:M11840 Factor: ERR3; motif: NNSAAGGTCRN 0.0489989377755291 1116 6 3 0.5 0.00268817204301075
TF TF:M04691_1 Factor: Kaiso; motif: TCTCGCGAG; match class: 1 0.0494316447798289 10488 62 44 0.709677419354839 0.0041952707856598
TF TF:M00695 Factor: ETF; motif: GVGGMGG 0.0496648283598029 10430 51 37 0.725490196078431 0.00354745925215724

pEpiTp01 transcription factor target enrichment of top program genes

TF enrichment of pEpiTp01
Possible regulators of activation of pEpiTp01 in epithelial cells. (Left) pearson correlation of TF expression and gene expression program activatity in Epithelial cells, (right) negative log p-value for enrichment of TF binding sites among top uniqueness weighted genes for the gene program. Blue bars indicate significant TFs meeting the following criteria: FDR<0.1, overlap > 2, Corr. R > 0, permutation based p-value < 0.05.