pS08 program activity among Stromal cells

Activation of pS08
pS08 gene program activation in Stromal cells.
Gene program activation of pS08 by different cell subtypes
pS08 gene program activation among cells of different subtypes (Stromal cells).

pS08 top program genes

Top genes of pS08 program
Bar plots showing the top genes for each gene program, ranked by (left) unique weights, (right) raw weights.

pS08 gene-set enrichment of top program genes (using g-profiler)

GSEA wth gene profiler of pS08
pS08 gene-set enrichment summary using g-profiler webtool.
Source termID Name Padj Tsize Qsize Overlap Precision Recall
CORUM CORUM:2346 ITGAV-ITGB5-ADAM9 complex 0.000589160994690949 3 59 3 0.0508474576271186 1
GO:BP GO:0043062 extracellular structure organization 1.76596654392553e-37 402 47 31 0.659574468085106 0.0771144278606965
GO:BP GO:0030198 extracellular matrix organization 1.76596654392553e-37 401 47 31 0.659574468085106 0.0773067331670823
GO:BP GO:0045229 external encapsulating structure organization 1.76596654392553e-37 404 47 31 0.659574468085106 0.0767326732673267
GO:BP GO:0030199 collagen fibril organization 2.70088924497904e-20 58 61 14 0.229508196721311 0.241379310344828
GO:BP GO:0032963 collagen metabolic process 1.24749783439759e-13 114 135 16 0.118518518518519 0.140350877192982
GO:BP GO:0022610 biological adhesion 1.79323240736262e-12 1499 61 28 0.459016393442623 0.018679119412942
GO:BP GO:0007155 cell adhesion 1.79323240736262e-12 1492 61 28 0.459016393442623 0.0187667560321716
GO:BP GO:0018126 protein hydroxylation 5.42644763450232e-11 28 126 9 0.0714285714285714 0.321428571428571
GO:BP GO:0031589 cell-substrate adhesion 2.47810642898084e-10 367 61 15 0.245901639344262 0.0408719346049046
GO:BP GO:0035987 endodermal cell differentiation 2.19715611502746e-09 45 115 9 0.0782608695652174 0.2
GO:BP GO:0042060 wound healing 2.33290063343556e-09 549 28 12 0.428571428571429 0.0218579234972678
GO:BP GO:0007492 endoderm development 3.2337807430421e-09 80 44 8 0.181818181818182 0.1
GO:BP GO:0009653 anatomical structure morphogenesis 4.23359812474777e-09 2797 46 27 0.58695652173913 0.00965319985698963
GO:BP GO:0043687 post-translational protein modification 5.82058781782737e-09 362 34 11 0.323529411764706 0.0303867403314917
GO:BP GO:0009611 response to wounding 6.9373000482613e-09 674 32 13 0.40625 0.0192878338278932
GO:BP GO:0001706 endoderm formation 7.57382270691133e-09 54 44 7 0.159090909090909 0.12962962962963
GO:BP GO:0048856 anatomical structure development 1.31470179906993e-08 6106 53 41 0.773584905660377 0.00671470684572552
GO:BP GO:0009888 tissue development 2.23098269508718e-08 2107 46 23 0.5 0.0109159943046986
GO:BP GO:0032502 developmental process 3.31089819868904e-08 6628 53 42 0.792452830188679 0.00633675316837658
GO:BP GO:0007160 cell-matrix adhesion 4.03355720976395e-08 235 61 11 0.180327868852459 0.0468085106382979
GO:BP GO:0001501 skeletal system development 4.12355339806552e-08 504 24 10 0.416666666666667 0.0198412698412698
GO:BP GO:0001704 formation of primary germ layer 5.80669803502322e-08 123 44 8 0.181818181818182 0.0650406504065041
GO:BP GO:0016477 cell migration 8.06062538565407e-08 1649 46 20 0.434782608695652 0.0121285627653123
GO:BP GO:0097435 supramolecular fiber organization 1.04042487260385e-07 734 44 14 0.318181818181818 0.0190735694822888
GO:BP GO:0007275 multicellular organism development 1.04042487260385e-07 5613 47 35 0.74468085106383 0.00623552467486193
GO:BP GO:0017185 peptidyl-lysine hydroxylation 1.75577619848084e-07 9 126 5 0.0396825396825397 0.555555555555556
GO:BP GO:0071230 cellular response to amino acid stimulus 2.47230273424916e-07 68 6 4 0.666666666666667 0.0588235294117647
GO:BP GO:0016043 cellular component organization 2.77867310267691e-07 6566 47 37 0.787234042553192 0.00563508985683826
GO:BP GO:0032964 collagen biosynthetic process 3.62009867704374e-07 56 126 8 0.0634920634920635 0.142857142857143
GO:BP GO:0051674 localization of cell 3.62009867704374e-07 1828 46 20 0.434782608695652 0.0109409190371991
GO:BP GO:0071229 cellular response to acid chemical 3.62009867704374e-07 76 6 4 0.666666666666667 0.0526315789473684
GO:BP GO:0048870 cell motility 3.62009867704374e-07 1828 46 20 0.434782608695652 0.0109409190371991
GO:BP GO:0030168 platelet activation 4.37876542898944e-07 160 4 4 1 0.025
GO:BP GO:0071840 cellular component organization or biogenesis 5.73493750863868e-07 6760 47 37 0.787234042553192 0.00547337278106509
GO:BP GO:0071559 response to transforming growth factor beta 8.25299547441727e-07 262 76 11 0.144736842105263 0.0419847328244275
GO:BP GO:0007369 gastrulation 9.00888416231299e-07 185 44 8 0.181818181818182 0.0432432432432432
GO:BP GO:0048513 animal organ development 1.45955720563297e-06 3672 39 24 0.615384615384615 0.0065359477124183
GO:BP GO:0043200 response to amino acid 1.48501266169815e-06 115 6 4 0.666666666666667 0.0347826086956522
GO:BP GO:0040011 locomotion 1.72190373158584e-06 2028 46 20 0.434782608695652 0.00986193293885602
GO:BP GO:0061448 connective tissue development 1.80107699941575e-06 256 24 7 0.291666666666667 0.02734375
GO:BP GO:0048731 system development 2.24302765986631e-06 5052 40 28 0.7 0.00554235946159937
GO:BP GO:0001503 ossification 2.30326943599475e-06 417 24 8 0.333333333333333 0.0191846522781775
GO:BP GO:0019511 peptidyl-proline hydroxylation 2.43933662276457e-06 16 117 5 0.0427350427350427 0.3125
GO:BP GO:0001101 response to acid chemical 2.45050068852371e-06 135 6 4 0.666666666666667 0.0296296296296296
GO:BP GO:0060348 bone development 3.4892030788684e-06 203 141 12 0.0851063829787234 0.0591133004926108
GO:BP GO:0009719 response to endogenous stimulus 3.67273405988096e-06 1683 29 14 0.482758620689655 0.0083184789067142
GO:BP GO:0007229 integrin-mediated signaling pathway 3.68565889638693e-06 111 59 7 0.11864406779661 0.0630630630630631
GO:BP GO:0072359 circulatory system development 3.69573750568999e-06 1194 28 12 0.428571428571429 0.0100502512562814
GO:BP GO:0071560 cellular response to transforming growth factor beta stimulus 5.64097337420612e-06 256 76 10 0.131578947368421 0.0390625
GO:BP GO:0018208 peptidyl-proline modification 6.30515479942449e-06 61 117 7 0.0598290598290598 0.114754098360656
GO:BP GO:0007596 blood coagulation 6.32809569491263e-06 347 4 4 1 0.0115273775216138
GO:BP GO:0034446 substrate adhesion-dependent cell spreading 6.32809569491263e-06 109 40 6 0.15 0.055045871559633
GO:BP GO:0007599 hemostasis 6.32809569491263e-06 351 4 4 1 0.0113960113960114
GO:BP GO:0043588 skin development 6.32809569491263e-06 424 7 5 0.714285714285714 0.0117924528301887
GO:BP GO:0050817 coagulation 6.42771825276545e-06 354 4 4 1 0.0112994350282486
GO:BP GO:0001568 blood vessel development 6.79587336207461e-06 792 28 10 0.357142857142857 0.0126262626262626
GO:BP GO:0032501 multicellular organismal process 6.92745942973638e-06 7946 42 35 0.833333333333333 0.00440473194059904
GO:BP GO:0018057 peptidyl-lysine oxidation 9.44403852976667e-06 5 52 3 0.0576923076923077 0.6
GO:BP GO:0001944 vasculature development 9.97249448229701e-06 830 28 10 0.357142857142857 0.0120481927710843
GO:BP GO:0006928 movement of cell or subcellular component 1.00134483561113e-05 2311 46 20 0.434782608695652 0.00865426222414539
GO:BP GO:0048646 anatomical structure formation involved in morphogenesis 1.22051735730708e-05 1202 121 25 0.206611570247934 0.0207986688851913
GO:BP GO:0010033 response to organic substance 1.38047877745127e-05 3412 29 18 0.620689655172414 0.00527549824150059
GO:BP GO:0070848 response to growth factor 1.89000387102263e-05 759 76 15 0.197368421052632 0.0197628458498024
GO:BP GO:0085029 extracellular matrix assembly 1.89000387102263e-05 47 115 6 0.0521739130434783 0.127659574468085
GO:BP GO:0090110 COPII-coated vesicle cargo loading 1.91389619560097e-05 15 82 4 0.0487804878048781 0.266666666666667
GO:BP GO:0050878 regulation of body fluid levels 2.35769876856986e-05 514 4 4 1 0.00778210116731518
GO:BP GO:0030574 collagen catabolic process 4.57201002923645e-05 47 135 6 0.0444444444444444 0.127659574468085
GO:BP GO:0048598 embryonic morphogenesis 7.36538445376146e-05 595 135 17 0.125925925925926 0.0285714285714286
GO:BP GO:0007179 transforming growth factor beta receptor signaling pathway 8.12083223687897e-05 206 76 8 0.105263157894737 0.0388349514563107
GO:BP GO:0033273 response to vitamin 9.90301591332263e-05 98 19 4 0.210526315789474 0.0408163265306122
GO:BP GO:0030154 cell differentiation 0.000126756314299605 4350 47 26 0.553191489361702 0.00597701149425287
GO:BP GO:0033627 cell adhesion mediated by integrin 0.000126756314299605 73 59 5 0.0847457627118644 0.0684931506849315
GO:BP GO:0071495 cellular response to endogenous stimulus 0.000126756314299605 1422 23 10 0.434782608695652 0.0070323488045007
GO:BP GO:0009790 embryo development 0.000139557349785473 1035 44 12 0.272727272727273 0.0115942028985507
GO:BP GO:1901700 response to oxygen-containing compound 0.000153287485592706 1739 20 10 0.5 0.00575043128234618
GO:BP GO:0051216 cartilage development 0.000158073048957478 196 24 5 0.208333333333333 0.0255102040816327
GO:BP GO:0071295 cellular response to vitamin 0.000161224661239603 33 19 3 0.157894736842105 0.0909090909090909
GO:BP GO:0035459 vesicle cargo loading 0.000164446956719386 26 82 4 0.0487804878048781 0.153846153846154
GO:BP GO:0048869 cellular developmental process 0.00016632010701552 4428 47 26 0.553191489361702 0.00587172538392051
GO:BP GO:0009887 animal organ morphogenesis 0.000181615081212721 1073 138 23 0.166666666666667 0.0214352283317801
GO:BP GO:0042221 response to chemical 0.000193428949142799 4781 47 27 0.574468085106383 0.00564735411001882
GO:BP GO:0018158 protein oxidation 0.000230321552046074 14 52 3 0.0576923076923077 0.214285714285714
GO:BP GO:0034097 response to cytokine 0.000236846752113684 1226 28 10 0.357142857142857 0.00815660685154975
GO:BP GO:0071363 cellular response to growth factor stimulus 0.000279366160342283 731 76 13 0.171052631578947 0.0177838577291382
GO:BP GO:0071310 cellular response to organic substance 0.000356955023416434 2776 6 6 1 0.00216138328530259
GO:BP GO:0031670 cellular response to nutrient 0.000369771453944217 45 19 3 0.157894736842105 0.0666666666666667
GO:BP GO:0035295 tube development 0.000414434721872106 1146 92 18 0.195652173913043 0.0157068062827225
GO:BP GO:0035239 tube morphogenesis 0.00045096580174462 950 121 19 0.15702479338843 0.02
GO:BP GO:0007178 transmembrane receptor protein serine/threonine kinase signaling pathway 0.00046686919239797 369 92 10 0.108695652173913 0.02710027100271
GO:BP GO:0030324 lung development 0.000484038872242879 173 58 6 0.103448275862069 0.0346820809248555
GO:BP GO:0030323 respiratory tube development 0.000545115578948886 177 58 6 0.103448275862069 0.0338983050847458
GO:BP GO:0071417 cellular response to organonitrogen compound 0.000650623187365376 666 6 4 0.666666666666667 0.00600600600600601
GO:BP GO:0090287 regulation of cellular response to growth factor stimulus 0.000759588223403533 315 114 10 0.087719298245614 0.0317460317460317
GO:BP GO:0007584 response to nutrient 0.000837023407802806 182 19 4 0.210526315789474 0.021978021978022
GO:BP GO:0022617 extracellular matrix disassembly 0.000837023407802806 82 135 6 0.0444444444444444 0.0731707317073171
GO:BP GO:0010810 regulation of cell-substrate adhesion 0.000844920768357375 222 31 5 0.161290322580645 0.0225225225225225
GO:BP GO:1901699 cellular response to nitrogen compound 0.000860163256402754 724 6 4 0.666666666666667 0.00552486187845304
GO:BP GO:0010243 response to organonitrogen compound 0.00087899488005125 1085 8 5 0.625 0.00460829493087558
GO:BP GO:0060541 respiratory system development 0.000971939271389184 199 58 6 0.103448275862069 0.0301507537688442
GO:BP GO:0018401 peptidyl-proline hydroxylation to 4-hydroxy-L-proline 0.000979535221461888 11 117 3 0.0256410256410256 0.272727272727273
GO:BP GO:0070887 cellular response to chemical stimulus 0.00100025625058408 3393 6 6 1 0.0017683465959328
GO:BP GO:0001775 cell activation 0.00106470285213321 1495 4 4 1 0.00267558528428094
GO:BP GO:0050793 regulation of developmental process 0.00111541459168567 2605 28 13 0.464285714285714 0.00499040307101727
GO:BP GO:1901698 response to nitrogen compound 0.00120698726702056 1172 8 5 0.625 0.00426621160409556
GO:BP GO:0051043 regulation of membrane protein ectodomain proteolysis 0.00140508017392159 24 59 3 0.0508474576271186 0.125
GO:BP GO:0007507 heart development 0.00142668361306597 578 8 4 0.5 0.0069204152249135
GO:BP GO:0009612 response to mechanical stimulus 0.00149690633346593 218 19 4 0.210526315789474 0.018348623853211
GO:BP GO:0001649 osteoblast differentiation 0.00169283296139327 232 35 5 0.142857142857143 0.021551724137931
GO:BP GO:0060350 endochondral bone morphogenesis 0.00169415029240463 58 138 5 0.036231884057971 0.0862068965517241
GO:BP GO:0048514 blood vessel morphogenesis 0.00170261652383411 711 28 7 0.25 0.00984528832630099
GO:BP GO:0002474 antigen processing and presentation of peptide antigen via MHC class I 0.00171088342654736 99 81 5 0.0617283950617284 0.0505050505050505
GO:BP GO:0050900 leukocyte migration 0.00182583206910882 511 4 3 0.75 0.00587084148727984
GO:BP GO:0001667 ameboidal-type cell migration 0.00186762847594639 494 28 6 0.214285714285714 0.0121457489878543
GO:BP GO:0035904 aorta development 0.0018920991411597 58 74 4 0.0540540540540541 0.0689655172413793
GO:BP GO:0060349 bone morphogenesis 0.00223139755523419 99 138 6 0.0434782608695652 0.0606060606060606
GO:BP GO:0051093 negative regulation of developmental process 0.00243642784682535 977 16 6 0.375 0.00614124872057318
GO:BP GO:0006888 endoplasmic reticulum to Golgi vesicle-mediated transport 0.00253898242245663 206 131 8 0.0610687022900763 0.0388349514563107
GO:BP GO:0002478 antigen processing and presentation of exogenous peptide antigen 0.00254009683350266 174 81 6 0.0740740740740741 0.0344827586206897
GO:BP GO:0019884 antigen processing and presentation of exogenous antigen 0.00319594305760314 182 81 6 0.0740740740740741 0.032967032967033
GO:BP GO:0030334 regulation of cell migration 0.00319600621424864 999 3 3 1 0.003003003003003
GO:BP GO:0016192 vesicle-mediated transport 0.00326705344875191 2180 109 27 0.247706422018349 0.0123853211009174
GO:BP GO:0006509 membrane protein ectodomain proteolysis 0.00326705344875191 43 118 4 0.0338983050847458 0.0930232558139535
GO:BP GO:0007167 enzyme linked receptor protein signaling pathway 0.00326705344875191 1103 76 14 0.184210526315789 0.0126926563916591
GO:BP GO:0140253 cell-cell fusion 0.00331132747107997 55 93 4 0.043010752688172 0.0727272727272727
GO:BP GO:0000768 syncytium formation by plasma membrane fusion 0.00331132747107997 55 93 4 0.043010752688172 0.0727272727272727
GO:BP GO:0030155 regulation of cell adhesion 0.00331132747107997 748 61 10 0.163934426229508 0.0133689839572193
GO:BP GO:0000904 cell morphogenesis involved in differentiation 0.00339366527076375 749 138 16 0.115942028985507 0.0213618157543391
GO:BP GO:0009628 response to abiotic stimulus 0.0035539273576345 1261 25 8 0.32 0.0063441712926249
GO:BP GO:2000145 regulation of cell motility 0.0035539273576345 1061 3 3 1 0.00282752120640905
GO:BP GO:0006949 syncytium formation 0.0036766781583739 57 93 4 0.043010752688172 0.0701754385964912
GO:BP GO:0048208 COPII vesicle coating 0.00371524245412079 65 82 4 0.0487804878048781 0.0615384615384615
GO:BP GO:0048207 vesicle targeting, rough ER to cis-Golgi 0.00371524245412079 65 82 4 0.0487804878048781 0.0615384615384615
GO:BP GO:0048002 antigen processing and presentation of peptide antigen 0.00375490347225616 192 81 6 0.0740740740740741 0.03125
GO:BP GO:0061035 regulation of cartilage development 0.00378629966604549 71 76 4 0.0526315789473684 0.0563380281690141
GO:BP GO:0040012 regulation of locomotion 0.00378629966604549 1104 3 3 1 0.00271739130434783
GO:BP GO:0071345 cellular response to cytokine stimulus 0.00380851124058657 1132 28 8 0.285714285714286 0.00706713780918728
GO:BP GO:0006903 vesicle targeting 0.00408883825047381 94 108 5 0.0462962962962963 0.0531914893617021
GO:BP GO:0051270 regulation of cellular component movement 0.00409665223584309 1141 3 3 1 0.00262927256792287
GO:BP GO:0031346 positive regulation of cell projection organization 0.00409931719964286 359 129 10 0.0775193798449612 0.0278551532033426
GO:BP GO:0045595 regulation of cell differentiation 0.00413889965614531 1679 25 9 0.36 0.0053603335318642
GO:BP GO:0006901 vesicle coating 0.00431468786123086 69 82 4 0.0487804878048781 0.0579710144927536
GO:BP GO:1901701 cellular response to oxygen-containing compound 0.0044733091514132 1227 6 4 0.666666666666667 0.0032599837000815
GO:BP GO:0060560 developmental growth involved in morphogenesis 0.00458567732895522 236 129 8 0.062015503875969 0.0338983050847458
GO:BP GO:0035850 epithelial cell differentiation involved in kidney development 0.00461058153390245 48 121 4 0.0330578512396694 0.0833333333333333
GO:BP GO:0019538 protein metabolic process 0.00484159571164181 5808 36 22 0.611111111111111 0.00378787878787879
GO:BP GO:0048199 vesicle targeting, to, from or within Golgi 0.00485402694136227 73 82 4 0.0487804878048781 0.0547945205479452
GO:BP GO:0048592 eye morphogenesis 0.00485402694136227 155 16 3 0.1875 0.0193548387096774
GO:BP GO:0055114 obsolete oxidation-reduction process 0.00485402694136227 745 117 14 0.11965811965812 0.0187919463087248
GO:BP GO:0000902 cell morphogenesis 0.00485402694136227 1037 138 19 0.13768115942029 0.0183220829315333
GO:BP GO:0050772 positive regulation of axonogenesis 0.00485402694136227 84 129 5 0.0387596899224806 0.0595238095238095
GO:BP GO:0090114 COPII-coated vesicle budding 0.00485402694136227 72 82 4 0.0487804878048781 0.0555555555555556
GO:BP GO:0002576 platelet degranulation 0.00492356275707119 126 20 3 0.15 0.0238095238095238
GO:BP GO:0046718 viral entry into host cell 0.00534237067752751 141 44 4 0.0909090909090909 0.0283687943262411
GO:BP GO:0030335 positive regulation of cell migration 0.005444610034773 567 12 4 0.333333333333333 0.00705467372134039
GO:BP GO:0018215 protein phosphopantetheinylation 0.00599630345572362 344 72 7 0.0972222222222222 0.0203488372093023
GO:BP GO:0006950 response to stress 0.0060403543600892 4170 28 15 0.535714285714286 0.00359712230215827
GO:BP GO:0001655 urogenital system development 0.0060403543600892 337 121 9 0.0743801652892562 0.0267062314540059
GO:BP GO:2000147 positive regulation of cell motility 0.00616793928702305 591 12 4 0.333333333333333 0.00676818950930626
GO:BP GO:0048193 Golgi vesicle transport 0.00631746416376242 382 131 10 0.0763358778625954 0.0261780104712042
GO:BP GO:0040017 positive regulation of locomotion 0.00658622181625724 606 12 4 0.333333333333333 0.0066006600660066
GO:BP GO:0051272 positive regulation of cellular component movement 0.00658622181625724 604 12 4 0.333333333333333 0.00662251655629139
GO:BP GO:0071774 response to fibroblast growth factor 0.00683332262974046 153 19 3 0.157894736842105 0.0196078431372549
GO:BP GO:0044409 entry into host 0.00686237768459634 154 44 4 0.0909090909090909 0.025974025974026
GO:BP GO:0061005 cell differentiation involved in kidney development 0.00780893436166756 58 121 4 0.0330578512396694 0.0689655172413793
GO:BP GO:0019882 antigen processing and presentation 0.00805235020848113 234 81 6 0.0740740740740741 0.0256410256410256
GO:BP GO:0050776 regulation of immune response 0.00807792664817832 996 4 3 0.75 0.00301204819277108
GO:BP GO:0045785 positive regulation of cell adhesion 0.00808225403520718 437 61 7 0.114754098360656 0.0160183066361556
GO:BP GO:0033619 membrane protein proteolysis 0.00826370776340986 61 118 4 0.0338983050847458 0.0655737704918033
GO:BP GO:0009967 positive regulation of signal transduction 0.00840474726004113 1598 3 3 1 0.00187734668335419
GO:BP GO:0097006 regulation of plasma lipoprotein particle levels 0.00944790745501306 107 70 4 0.0571428571428571 0.0373831775700935
GO:BP GO:0001822 kidney development 0.00946682699032356 293 121 8 0.0661157024793388 0.0273037542662116
GO:BP GO:0022604 regulation of cell morphogenesis 0.00946682699032356 309 43 5 0.116279069767442 0.0161812297734628
GO:BP GO:0010811 positive regulation of cell-substrate adhesion 0.00956908454907386 124 61 4 0.0655737704918033 0.032258064516129
GO:BP GO:0060840 artery development 0.00956908454907386 102 74 4 0.0540540540540541 0.0392156862745098
GO:BP GO:0009725 response to hormone 0.00959202265689336 921 23 6 0.260869565217391 0.00651465798045603
GO:BP GO:0051179 localization 0.00983132297393158 6901 122 64 0.524590163934426 0.00927401825822345
GO:BP GO:0052126 movement in host environment 0.0101551234800988 177 44 4 0.0909090909090909 0.0225988700564972
GO:BP GO:0019886 antigen processing and presentation of exogenous peptide antigen via MHC class II 0.0103407665872633 96 81 4 0.0493827160493827 0.0416666666666667
GO:BP GO:0060284 regulation of cell development 0.0105807056251028 502 129 11 0.0852713178294574 0.0219123505976096
GO:BP GO:0010647 positive regulation of cell communication 0.0106580656393894 1777 3 3 1 0.00168823860438942
GO:BP GO:0023056 positive regulation of signaling 0.0106644333116104 1782 3 3 1 0.00168350168350168
GO:BP GO:0048729 tissue morphogenesis 0.0106644333116104 667 129 13 0.10077519379845 0.0194902548725637
GO:BP GO:0072001 renal system development 0.010712981526176 302 121 8 0.0661157024793388 0.0264900662251656
GO:BP GO:0007166 cell surface receptor signaling pathway 0.0108816556900424 3210 4 4 1 0.00124610591900312
GO:BP GO:0071711 basement membrane organization 0.0108816556900424 31 115 3 0.0260869565217391 0.0967741935483871
GO:BP GO:0022603 regulation of anatomical structure morphogenesis 0.0108896034565611 1042 74 12 0.162162162162162 0.0115163147792706
GO:BP GO:0043542 endothelial cell migration 0.0112855248913533 290 13 3 0.230769230769231 0.0103448275862069
GO:BP GO:0003401 axis elongation 0.0112855248913533 30 121 3 0.0247933884297521 0.1
GO:BP GO:0071300 cellular response to retinoic acid 0.0113063364763455 67 121 4 0.0330578512396694 0.0597014925373134
GO:BP GO:0002495 antigen processing and presentation of peptide antigen via MHC class II 0.0113063364763455 100 81 4 0.0493827160493827 0.04
GO:BP GO:0002376 immune system process 0.0114240575510139 3278 4 4 1 0.0012202562538133
GO:BP GO:0048519 negative regulation of biological process 0.0114788733264035 5757 13 10 0.769230769230769 0.00173701580684384
GO:BP GO:0002062 chondrocyte differentiation 0.0116619682106184 108 76 4 0.0526315789473684 0.037037037037037
GO:BP GO:0018205 peptidyl-lysine modification 0.0117873896533977 405 72 7 0.0972222222222222 0.0172839506172839
GO:BP GO:0001525 angiogenesis 0.0119995474453493 617 92 10 0.108695652173913 0.0162074554294976
GO:BP GO:0002504 antigen processing and presentation of peptide or polysaccharide antigen via MHC class II 0.0122234073159529 103 81 4 0.0493827160493827 0.0388349514563107
GO:BP GO:1905314 semi-lunar valve development 0.0122234073159529 41 92 3 0.0326086956521739 0.0731707317073171
GO:BP GO:2000026 regulation of multicellular organismal development 0.0122762904235745 1447 28 8 0.285714285714286 0.0055286800276434
GO:BP GO:0036211 protein modification process 0.0125297052608324 4041 34 16 0.470588235294118 0.00395941598614204
GO:BP GO:0006464 cellular protein modification process 0.0125297052608324 4041 34 16 0.470588235294118 0.00395941598614204
GO:BP GO:0007423 sensory organ development 0.0125765962042916 567 39 6 0.153846153846154 0.0105820105820106
GO:BP GO:0052547 regulation of peptidase activity 0.0125887640806379 467 47 6 0.127659574468085 0.012847965738758
GO:BP GO:0001654 eye development 0.0125974958414723 379 39 5 0.128205128205128 0.0131926121372032
GO:BP GO:0032330 regulation of chondrocyte differentiation 0.0127625098513179 51 76 3 0.0394736842105263 0.0588235294117647
GO:BP GO:0150063 visual system development 0.0129852815759899 383 39 5 0.128205128205128 0.0130548302872063
GO:BP GO:0050896 response to stimulus 0.0134793519309926 9407 10 10 1 0.00106303816307005
GO:BP GO:0006900 vesicle budding from membrane 0.0134793519309926 107 82 4 0.0487804878048781 0.0373831775700935
GO:BP GO:0001958 endochondral ossification 0.0134793519309926 30 135 3 0.0222222222222222 0.1
GO:BP GO:0048880 sensory system development 0.0134793519309926 389 39 5 0.128205128205128 0.012853470437018
GO:BP GO:0036075 replacement ossification 0.0134793519309926 30 135 3 0.0222222222222222 0.1
GO:BP GO:0031667 response to nutrient levels 0.0134793519309926 482 19 4 0.210526315789474 0.00829875518672199
GO:BP GO:0043434 response to peptide hormone 0.0136686959940922 462 20 4 0.2 0.00865800865800866
GO:BP GO:0090596 sensory organ morphogenesis 0.0136686959940922 262 16 3 0.1875 0.0114503816793893
GO:BP GO:0031669 cellular response to nutrient levels 0.0136686959940922 219 19 3 0.157894736842105 0.0136986301369863
GO:BP GO:0006024 glycosaminoglycan biosynthetic process 0.0141681302020135 107 142 5 0.0352112676056338 0.0467289719626168
GO:BP GO:0048705 skeletal system morphogenesis 0.0155877879390183 226 138 7 0.0507246376811594 0.0309734513274336
GO:BP GO:0009991 response to extracellular stimulus 0.0155877879390183 512 19 4 0.210526315789474 0.0078125
GO:BP GO:0090092 regulation of transmembrane receptor protein serine/threonine kinase signaling pathway 0.0171333882213164 257 92 6 0.0652173913043478 0.0233463035019455
GO:BP GO:0051701 biological process involved in interaction with host 0.0171506147790137 221 44 4 0.0909090909090909 0.0180995475113122
GO:BP GO:0006023 aminoglycan biosynthetic process 0.0174853362758151 114 142 5 0.0352112676056338 0.043859649122807
GO:BP GO:0010631 epithelial cell migration 0.0177072335613257 370 13 3 0.230769230769231 0.00810810810810811
GO:BP GO:0031668 cellular response to extracellular stimulus 0.0177546843679688 248 19 3 0.157894736842105 0.0120967741935484
GO:BP GO:0090132 epithelium migration 0.0179338199281575 373 13 3 0.230769230769231 0.00804289544235925
GO:BP GO:0017015 regulation of transforming growth factor beta receptor signaling pathway 0.0179338199281575 129 76 4 0.0526315789473684 0.0310077519379845
GO:BP GO:0044267 cellular protein metabolic process 0.0180358107307978 5229 36 19 0.527777777777778 0.00363358194683496
GO:BP GO:0048584 positive regulation of response to stimulus 0.0180358107307978 2344 3 3 1 0.00127986348122867
GO:BP GO:0043412 macromolecule modification 0.0180541597615348 4257 34 16 0.470588235294118 0.00375851538642236
GO:BP GO:0002009 morphogenesis of an epithelium 0.0180541597615348 560 129 11 0.0852713178294574 0.0196428571428571
GO:BP GO:1903510 mucopolysaccharide metabolic process 0.0180541597615348 116 142 5 0.0352112676056338 0.0431034482758621
GO:BP GO:0090130 tissue migration 0.0180541597615348 379 13 3 0.230769230769231 0.0079155672823219
GO:BP GO:0070482 response to oxygen levels 0.0180541597615348 408 25 4 0.16 0.00980392156862745
GO:BP GO:0061564 axon development 0.0180541597615348 523 138 11 0.0797101449275362 0.0210325047801147
GO:BP GO:1903844 regulation of cellular response to transforming growth factor beta stimulus 0.0185628228127027 132 76 4 0.0526315789473684 0.0303030303030303
GO:BP GO:0051239 regulation of multicellular organismal process 0.0186452185312074 2861 28 11 0.392857142857143 0.00384480950716533
GO:BP GO:0010975 regulation of neuron projection development 0.0190130778584966 451 138 10 0.072463768115942 0.0221729490022173
GO:BP GO:0048523 negative regulation of cellular process 0.0195232856886161 5139 22 13 0.590909090909091 0.00252967503405332
GO:BP GO:0032940 secretion by cell 0.0196279045140757 1364 125 19 0.152 0.0139296187683284
GO:BP GO:0003179 heart valve morphogenesis 0.0197356864850248 54 92 3 0.0326086956521739 0.0555555555555556
GO:BP GO:0002682 regulation of immune system process 0.0197356864850248 1617 4 3 0.75 0.00185528756957328
GO:BP GO:0072006 nephron development 0.0197356864850248 142 121 5 0.0413223140495868 0.0352112676056338
GO:BP GO:0065008 regulation of biological quality 0.0197912382569666 4131 4 4 1 0.000968288549987896
GO:BP GO:0045596 negative regulation of cell differentiation 0.0199206543699106 697 16 4 0.25 0.00573888091822095
GO:BP GO:1901652 response to peptide 0.020117150203455 551 20 4 0.2 0.00725952813067151
GO:BP GO:1901564 organonitrogen compound metabolic process 0.0202043150322834 6792 61 34 0.557377049180328 0.00500588928150766
GO:BP GO:0048583 regulation of response to stimulus 0.0218815244794869 4278 4 4 1 0.000935016362786349
GO:BP GO:1990138 neuron projection extension 0.022931289842573 170 32 3 0.09375 0.0176470588235294
GO:BP GO:0051130 positive regulation of cellular component organization 0.0233253393473994 1153 129 17 0.131782945736434 0.0147441457068517
GO:BP GO:0010951 negative regulation of endopeptidase activity 0.0235239533634449 253 22 3 0.136363636363636 0.0118577075098814
GO:BP GO:0120035 regulation of plasma membrane bounded cell projection organization 0.024109062935106 638 138 12 0.0869565217391304 0.0188087774294671
GO:BP GO:0051094 positive regulation of developmental process 0.0242786494640224 1341 28 7 0.25 0.0052199850857569
GO:BP GO:0010976 positive regulation of neuron projection development 0.0245609755083545 165 112 5 0.0446428571428571 0.0303030303030303
GO:BP GO:0007409 axonogenesis 0.0246035910149545 478 138 10 0.072463768115942 0.0209205020920502
GO:BP GO:0051962 positive regulation of nervous system development 0.0246035910149545 276 129 7 0.0542635658914729 0.0253623188405797
GO:BP GO:0006890 retrograde vesicle-mediated transport, Golgi to endoplasmic reticulum 0.0246445491091916 87 131 4 0.0305343511450382 0.0459770114942529
GO:BP GO:0007162 negative regulation of cell adhesion 0.0248881879762857 304 19 3 0.157894736842105 0.00986842105263158
GO:BP GO:0007156 homophilic cell adhesion via plasma membrane adhesion molecules 0.0251602631384406 167 112 5 0.0446428571428571 0.029940119760479
GO:BP GO:0006887 exocytosis 0.0252215334702226 904 125 14 0.112 0.0154867256637168
GO:BP GO:0032835 glomerulus development 0.0253154023963407 62 92 3 0.0326086956521739 0.0483870967741935
GO:BP GO:0140352 export from cell 0.0253921889933153 1418 125 19 0.152 0.0133991537376587
GO:BP GO:0032879 regulation of localization 0.0258298608009501 2872 3 3 1 0.00104456824512535
GO:BP GO:0010466 negative regulation of peptidase activity 0.0258298608009501 267 22 3 0.136363636363636 0.0112359550561798
GO:BP GO:0003170 heart valve development 0.0261368689858644 63 92 3 0.0326086956521739 0.0476190476190476
GO:BP GO:0030162 regulation of proteolysis 0.02655421731263 752 76 9 0.118421052631579 0.011968085106383
GO:BP GO:0007411 axon guidance 0.0266908292770797 283 129 7 0.0542635658914729 0.0247349823321555
GO:BP GO:0097485 neuron projection guidance 0.0270447003267794 284 129 7 0.0542635658914729 0.0246478873239437
GO:BP GO:0010712 regulation of collagen metabolic process 0.0271680221831271 52 114 3 0.0263157894736842 0.0576923076923077
GO:BP GO:0071496 cellular response to external stimulus 0.0275922393802892 322 19 3 0.157894736842105 0.0093167701863354
GO:BP GO:0031344 regulation of cell projection organization 0.0276376143897159 656 138 12 0.0869565217391304 0.0182926829268293
GO:BP GO:0048468 cell development 0.0285046572656311 2100 40 11 0.275 0.00523809523809524
GO:BP GO:0033993 response to lipid 0.0308661577608321 918 23 5 0.217391304347826 0.00544662309368192
GO:BP GO:0032526 response to retinoic acid 0.0309116496172349 110 58 3 0.0517241379310345 0.0272727272727273
GO:BP GO:0009966 regulation of signal transduction 0.0310581191170792 3165 3 3 1 0.000947867298578199
GO:BP GO:0050770 regulation of axonogenesis 0.0322129698388979 159 129 5 0.0387596899224806 0.0314465408805031
GO:BP GO:0051240 positive regulation of multicellular organismal process 0.0322129698388979 1455 28 7 0.25 0.00481099656357388
GO:BP GO:0031099 regeneration 0.0322129698388979 206 32 3 0.09375 0.0145631067961165
GO:BP GO:0006897 endocytosis 0.0324439083549611 696 43 6 0.13953488372093 0.00862068965517241
GO:BP GO:0007044 cell-substrate junction assembly 0.0324621368246603 101 128 4 0.03125 0.0396039603960396
GO:BP GO:0010720 positive regulation of cell development 0.0332808065057269 302 129 7 0.0542635658914729 0.0231788079470199
GO:BP GO:0050769 positive regulation of neurogenesis 0.0334745414728426 229 129 6 0.0465116279069767 0.0262008733624454
GO:BP GO:0030512 negative regulation of transforming growth factor beta receptor signaling pathway 0.0336402935963181 88 76 3 0.0394736842105263 0.0340909090909091
GO:BP GO:0009100 glycoprotein metabolic process 0.034630611411715 424 142 9 0.0633802816901408 0.0212264150943396
GO:BP GO:0051716 cellular response to stimulus 0.034630611411715 7781 6 6 1 0.000771109111939339
GO:BP GO:0006508 proteolysis 0.0346532948785337 1836 47 11 0.234042553191489 0.00599128540305011
GO:BP GO:0014070 response to organic cyclic compound 0.0352751867722435 967 23 5 0.217391304347826 0.00517063081695967
GO:BP GO:0060429 epithelium development 0.0356378473049167 1325 101 15 0.148514851485149 0.0113207547169811
GO:BP GO:0060562 epithelial tube morphogenesis 0.0357019637667366 329 121 7 0.0578512396694215 0.0212765957446809
GO:BP GO:0046579 positive regulation of Ras protein signal transduction 0.0357019637667366 75 92 3 0.0326086956521739 0.04
GO:BP GO:0008652 cellular amino acid biosynthetic process 0.0361407409408145 79 88 3 0.0340909090909091 0.0379746835443038
GO:BP GO:0090288 negative regulation of cellular response to growth factor stimulus 0.0363170842883516 119 114 4 0.0350877192982456 0.0336134453781513
GO:BP GO:0150115 cell-substrate junction organization 0.0372429497362914 107 128 4 0.03125 0.0373831775700935
GO:BP GO:0046903 secretion 0.0372745978850298 1501 125 19 0.152 0.0126582278481013
GO:BP GO:0010035 response to inorganic substance 0.0375447971517859 575 13 3 0.230769230769231 0.00521739130434783
GO:BP GO:0019221 cytokine-mediated signaling pathway 0.0382434596665926 810 28 5 0.178571428571429 0.00617283950617284
GO:BP GO:0051241 negative regulation of multicellular organismal process 0.0382434596665926 1160 20 5 0.25 0.00431034482758621
GO:BP GO:0006487 protein N-linked glycosylation 0.0385061019531898 76 95 3 0.0315789473684211 0.0394736842105263
GO:BP GO:0010646 regulation of cell communication 0.0385588326064026 3543 3 3 1 0.000846740050804403
GO:BP GO:0006955 immune response 0.0385835927913004 2311 4 3 0.75 0.00129813933362181
GO:BP GO:0023051 regulation of signaling 0.0391740499930452 3578 3 3 1 0.000838457238680827
GO:BP GO:1903076 regulation of protein localization to plasma membrane 0.0396632090449301 105 70 3 0.0428571428571429 0.0285714285714286
GO:BP GO:0048588 developmental cell growth 0.0401286806336165 235 32 3 0.09375 0.0127659574468085
GO:BP GO:0098609 cell-cell adhesion 0.0401286806336165 894 59 8 0.135593220338983 0.00894854586129754
GO:BP GO:0030203 glycosaminoglycan metabolic process 0.0407120995267382 159 142 5 0.0352112676056338 0.0314465408805031
GO:BP GO:0051057 positive regulation of small GTPase mediated signal transduction 0.0407163640783956 82 92 3 0.0326086956521739 0.0365853658536585
GO:BP GO:0045055 regulated exocytosis 0.0407163640783956 785 54 7 0.12962962962963 0.0089171974522293
GO:BP GO:0045861 negative regulation of proteolysis 0.0426926211831665 359 22 3 0.136363636363636 0.00835654596100279
GO:BP GO:0051650 establishment of vesicle localization 0.0433596270348161 214 108 5 0.0462962962962963 0.0233644859813084
GO:BP GO:0071772 response to BMP 0.0435125583133069 171 46 3 0.0652173913043478 0.0175438596491228
GO:BP GO:0071773 cellular response to BMP stimulus 0.0435125583133069 171 46 3 0.0652173913043478 0.0175438596491228
GO:BP GO:0048545 response to steroid hormone 0.0437851718457389 349 23 3 0.130434782608696 0.00859598853868195
GO:BP GO:0006457 protein folding 0.0455367384726547 225 68 4 0.0588235294117647 0.0177777777777778
GO:BP GO:0019058 viral life cycle 0.0463695791314016 353 44 4 0.0909090909090909 0.0113314447592068
GO:BP GO:0034330 cell junction organization 0.0465786136446013 722 34 5 0.147058823529412 0.00692520775623269
GO:BP GO:0007219 Notch signaling pathway 0.0465786136446013 193 124 5 0.0403225806451613 0.0259067357512953
GO:BP GO:0030010 establishment of cell polarity 0.0466944491549189 142 58 3 0.0517241379310345 0.0211267605633803
GO:BP GO:0048589 developmental growth 0.0473687429098626 649 138 11 0.0797101449275362 0.0169491525423729
GO:BP GO:0006986 response to unfolded protein 0.0473758386917973 184 131 5 0.0381679389312977 0.0271739130434783
GO:CC GO:0005788 endoplasmic reticulum lumen 1.10142395239075e-33 307 38 25 0.657894736842105 0.0814332247557003
GO:CC GO:0031012 extracellular matrix 1.29137136597438e-28 562 53 29 0.547169811320755 0.0516014234875445
GO:CC GO:0030312 external encapsulating structure 1.29137136597438e-28 563 53 29 0.547169811320755 0.0515097690941385
GO:CC GO:0062023 collagen-containing extracellular matrix 2.55597470805856e-27 421 53 26 0.490566037735849 0.0617577197149644
GO:CC GO:0005783 endoplasmic reticulum 1.02767474252669e-21 1982 134 59 0.440298507462687 0.0297679112008073
GO:CC GO:0005581 collagen trimer 1.01280657497212e-20 95 23 12 0.521739130434783 0.126315789473684
GO:CC GO:0005576 extracellular region 8.86127659679013e-17 4567 47 40 0.851063829787234 0.00875848478213269
GO:CC GO:0005615 extracellular space 2.55701116908736e-16 3594 44 35 0.795454545454545 0.0097384529771842
GO:CC GO:0012505 endomembrane system 1.00054064625702e-15 4640 142 82 0.577464788732394 0.0176724137931034
GO:CC GO:0005583 fibrillar collagen trimer 2.85818543725184e-14 12 7 5 0.714285714285714 0.416666666666667
GO:CC GO:0098643 banded collagen fibril 2.85818543725184e-14 12 7 5 0.714285714285714 0.416666666666667
GO:CC GO:0005604 basement membrane 2.90717575664991e-14 97 34 10 0.294117647058824 0.103092783505155
GO:CC GO:0098644 complex of collagen trimers 6.20888720859741e-13 21 7 5 0.714285714285714 0.238095238095238
GO:CC GO:0071944 cell periphery 3.22445483647208e-11 6169 61 47 0.770491803278688 0.00761873885556816
GO:CC GO:0070062 extracellular exosome 1.2215013141898e-08 2176 77 30 0.38961038961039 0.0137867647058824
GO:CC GO:1903561 extracellular vesicle 2.78706138228737e-08 2261 77 30 0.38961038961039 0.0132684652808492
GO:CC GO:0043230 extracellular organelle 2.78706138228737e-08 2263 77 30 0.38961038961039 0.0132567388422448
GO:CC GO:0031982 vesicle 3.52424063653649e-08 4055 54 32 0.592592592592593 0.00789149198520345
GO:CC GO:0005588 collagen type V trimer 4.02635500256244e-08 4 128 4 0.03125 1
GO:CC GO:0070013 intracellular organelle lumen 1.74188486262e-07 5402 34 26 0.764705882352941 0.00481303221029248
GO:CC GO:0031974 membrane-enclosed lumen 3.13625512148579e-07 5565 34 26 0.764705882352941 0.00467205750224618
GO:CC GO:0043233 organelle lumen 3.13625512148579e-07 5565 34 26 0.764705882352941 0.00467205750224618
GO:CC GO:0099512 supramolecular fiber 2.18816638000371e-06 993 7 6 0.857142857142857 0.00604229607250755
GO:CC GO:0099081 supramolecular polymer 2.20368077049192e-06 1001 7 6 0.857142857142857 0.00599400599400599
GO:CC GO:0030120 vesicle coat 2.45035215367787e-06 55 85 6 0.0705882352941176 0.109090909090909
GO:CC GO:0005794 Golgi apparatus 4.28068215465087e-06 1623 142 32 0.225352112676056 0.0197165742452249
GO:CC GO:0005925 focal adhesion 5.09960685308988e-06 420 70 11 0.157142857142857 0.0261904761904762
GO:CC GO:0030055 cell-substrate junction 5.606614832664e-06 427 70 11 0.157142857142857 0.0257611241217799
GO:CC GO:0030127 COPII vesicle coat 5.606614832664e-06 15 82 4 0.0487804878048781 0.266666666666667
GO:CC GO:0099080 supramolecular complex 9.36262589002991e-06 1323 7 6 0.857142857142857 0.00453514739229025
GO:CC GO:0005793 endoplasmic reticulum-Golgi intermediate compartment 9.96656187865701e-06 131 108 8 0.0740740740740741 0.0610687022900763
GO:CC GO:0031984 organelle subcompartment 2.30022914649013e-05 1773 142 32 0.225352112676056 0.01804850535815
GO:CC GO:0098791 Golgi apparatus subcompartment 2.92139070461291e-05 885 142 21 0.147887323943662 0.023728813559322
GO:CC GO:0008305 integrin complex 3.40005167125873e-05 32 61 4 0.0655737704918033 0.125
GO:CC GO:0030117 membrane coat 4.79275645560337e-05 97 85 6 0.0705882352941176 0.0618556701030928
GO:CC GO:0048475 coated membrane 4.79275645560337e-05 97 85 6 0.0705882352941176 0.0618556701030928
GO:CC GO:0000139 Golgi membrane 4.80873140145062e-05 771 142 19 0.133802816901408 0.0246433203631647
GO:CC GO:0098636 protein complex involved in cell adhesion 5.43547286440114e-05 37 61 4 0.0655737704918033 0.108108108108108
GO:CC GO:0070971 endoplasmic reticulum exit site 8.20628438078476e-05 31 82 4 0.0487804878048781 0.129032258064516
GO:CC GO:0009986 cell surface 9.46622711175976e-05 899 118 18 0.152542372881356 0.0200222469410456
GO:CC GO:0030662 coated vesicle membrane 0.000123140623675587 177 85 7 0.0823529411764706 0.0395480225988701
GO:CC GO:0005737 cytoplasm 0.000176701713514571 11911 129 103 0.798449612403101 0.00864746872638737
GO:CC GO:0030660 Golgi-associated vesicle membrane 0.000234921710013516 52 131 5 0.0381679389312977 0.0961538461538462
GO:CC GO:0048770 pigment granule 0.000324754428059243 105 70 5 0.0714285714285714 0.0476190476190476
GO:CC GO:0042470 melanosome 0.000324754428059243 105 70 5 0.0714285714285714 0.0476190476190476
GO:CC GO:0031093 platelet alpha granule lumen 0.000324754428059243 66 20 3 0.15 0.0454545454545455
GO:CC GO:0043227 membrane-bounded organelle 0.000324754428059243 12858 45 42 0.933333333333333 0.00326644890340644
GO:CC GO:0043256 laminin complex 0.000328481430354202 12 115 3 0.0260869565217391 0.25
GO:CC GO:0005798 Golgi-associated vesicle 0.000336931318647449 94 131 6 0.0458015267175573 0.0638297872340425
GO:CC GO:0042383 sarcolemma 0.000350179693465851 140 28 4 0.142857142857143 0.0285714285714286
GO:CC GO:0030659 cytoplasmic vesicle membrane 0.000644178492168321 779 131 16 0.122137404580153 0.0205391527599487
GO:CC GO:0012507 ER to Golgi transport vesicle membrane 0.000715471386515102 57 82 4 0.0487804878048781 0.0701754385964912
GO:CC GO:0098588 bounding membrane of organelle 0.000715471386515102 2158 142 32 0.225352112676056 0.0148285449490269
GO:CC GO:0031091 platelet alpha granule 0.000715471386515102 90 20 3 0.15 0.0333333333333333
GO:CC GO:0012506 vesicle membrane 0.00080520676691054 800 131 16 0.122137404580153 0.02
GO:CC GO:0005789 endoplasmic reticulum membrane 0.00080520676691054 1117 95 16 0.168421052631579 0.0143240823634736
GO:CC GO:0098827 endoplasmic reticulum subcompartment 0.000822789490101547 1122 95 16 0.168421052631579 0.0142602495543672
GO:CC GO:0030133 transport vesicle 0.000863497005297519 414 131 11 0.083969465648855 0.0265700483091787
GO:CC GO:0043231 intracellular membrane-bounded organelle 0.00090108657757017 11296 27 25 0.925925925925926 0.00221317280453258
GO:CC GO:0042175 nuclear outer membrane-endoplasmic reticulum membrane network 0.000919749998945773 1139 95 16 0.168421052631579 0.0140474100087796
GO:CC GO:0030867 rough endoplasmic reticulum membrane 0.00101455919418951 29 72 3 0.0416666666666667 0.103448275862069
GO:CC GO:0032991 protein-containing complex 0.00102485309244923 5548 7 7 1 0.00126171593366979
GO:CC GO:0070161 anchoring junction 0.00126554998844078 836 70 11 0.157142857142857 0.0131578947368421
GO:CC GO:0030663 COPI-coated vesicle membrane 0.00132548006969696 18 131 3 0.0229007633587786 0.166666666666667
GO:CC GO:0031594 neuromuscular junction 0.00134383687804619 73 32 3 0.09375 0.0410958904109589
GO:CC GO:0005791 rough endoplasmic reticulum 0.00169679565382439 86 72 4 0.0555555555555556 0.0465116279069767
GO:CC GO:0030135 coated vesicle 0.00187803900373533 295 85 7 0.0823529411764706 0.023728813559322
GO:CC GO:0030141 secretory granule 0.00315042365272186 851 54 9 0.166666666666667 0.0105757931844888
GO:CC GO:0030027 lamellipodium 0.00317674556001755 200 137 7 0.0510948905109489 0.035
GO:CC GO:0030134 COPII-coated ER to Golgi transport vesicle 0.00317674556001755 90 82 4 0.0487804878048781 0.0444444444444444
GO:CC GO:0031410 cytoplasmic vesicle 0.00389841770392662 2424 85 22 0.258823529411765 0.00907590759075908
GO:CC GO:0097708 intracellular vesicle 0.00393713779098687 2428 85 22 0.258823529411765 0.00906095551894563
GO:CC GO:0030137 COPI-coated vesicle 0.00427648540257717 28 131 3 0.0229007633587786 0.107142857142857
GO:CC GO:0043226 organelle 0.00427648540257717 14008 45 42 0.933333333333333 0.0029982866933181
GO:CC GO:0043229 intracellular organelle 0.00570014463247134 12491 16 16 1 0.0012809222640301
GO:CC GO:0030175 filopodium 0.00658093594622081 107 40 3 0.075 0.0280373831775701
GO:CC GO:0031985 Golgi cisterna 0.00764312364394534 115 142 5 0.0352112676056338 0.0434782608695652
GO:CC GO:0030658 transport vesicle membrane 0.00923220699468962 209 82 5 0.0609756097560976 0.0239234449760766
GO:CC GO:0099503 secretory vesicle 0.00933537387995137 1020 54 9 0.166666666666667 0.00882352941176471
GO:CC GO:0140534 endoplasmic reticulum protein-containing complex 0.0148563001143007 128 95 4 0.0421052631578947 0.03125
GO:CC GO:0034774 secretory granule lumen 0.0156669014710709 320 20 3 0.15 0.009375
GO:CC GO:0060205 cytoplasmic vesicle lumen 0.0159412713361391 324 20 3 0.15 0.00925925925925926
GO:CC GO:0031983 vesicle lumen 0.0160713267428267 326 20 3 0.15 0.00920245398773006
GO:CC GO:0032580 Golgi cisterna membrane 0.0161444917219126 90 142 4 0.028169014084507 0.0444444444444444
GO:CC GO:0005795 Golgi stack 0.0177176907429946 149 142 5 0.0352112676056338 0.0335570469798658
GO:CC GO:0042581 specific granule 0.0220927876031389 158 47 3 0.0638297872340425 0.0189873417721519
GO:CC GO:0016020 membrane 0.0241560980696998 9838 143 89 0.622377622377622 0.00904655417767839
GO:CC GO:0033116 endoplasmic reticulum-Golgi intermediate compartment membrane 0.0258380554258379 74 108 3 0.0277777777777778 0.0405405405405405
GO:CC GO:0009897 external side of plasma membrane 0.0258380554258379 408 59 5 0.0847457627118644 0.0122549019607843
GO:CC GO:0031090 organelle membrane 0.0263407046635247 3612 142 39 0.274647887323944 0.010797342192691
GO:CC GO:0030667 secretory granule membrane 0.0311298644197176 303 54 4 0.0740740740740741 0.0132013201320132
GO:CC GO:0098858 actin-based cell projection 0.031514334067966 220 40 3 0.075 0.0136363636363636
GO:CC GO:0030054 cell junction 0.0321146947190852 2105 59 13 0.220338983050847 0.00617577197149644
GO:CC GO:0031252 cell leading edge 0.0324588643023053 422 137 8 0.0583941605839416 0.018957345971564
GO:CC GO:0098802 plasma membrane signaling receptor complex 0.0418443504127731 300 61 4 0.0655737704918033 0.0133333333333333
GO:CC GO:0005622 intracellular anatomical structure 0.0489358994023634 14790 16 16 1 0.00108181203515889
GO:MF GO:0005201 extracellular matrix structural constituent 8.2661458851831e-27 171 38 19 0.5 0.111111111111111
GO:MF GO:0030020 extracellular matrix structural constituent conferring tensile strength 1.85385493150059e-19 41 14 9 0.642857142857143 0.219512195121951
GO:MF GO:0005518 collagen binding 3.75002977417941e-16 70 59 12 0.203389830508475 0.171428571428571
GO:MF GO:0005198 structural molecule activity 1.09391186299316e-15 698 38 19 0.5 0.0272206303724928
GO:MF GO:0048407 platelet-derived growth factor binding 4.15057369882427e-14 11 7 5 0.714285714285714 0.454545454545455
GO:MF GO:0005178 integrin binding 3.02990160335478e-12 147 61 12 0.19672131147541 0.0816326530612245
GO:MF GO:0050839 cell adhesion molecule binding 7.96949162116636e-10 546 61 16 0.262295081967213 0.0293040293040293
GO:MF GO:0044877 protein-containing complex binding 1.92788447574441e-09 1287 61 22 0.360655737704918 0.0170940170940171
GO:MF GO:0002020 protease binding 1.01834718571143e-08 133 79 10 0.126582278481013 0.075187969924812
GO:MF GO:0019838 growth factor binding 1.72144673706148e-08 138 7 5 0.714285714285714 0.036231884057971
GO:MF GO:0019798 procollagen-proline dioxygenase activity 1.79829106555188e-08 8 117 5 0.0427350427350427 0.625
GO:MF GO:0031418 L-ascorbic acid binding 9.00960649216205e-08 21 117 6 0.0512820512820513 0.285714285714286
GO:MF GO:0043394 proteoglycan binding 2.97609416875369e-07 36 38 5 0.131578947368421 0.138888888888889
GO:MF GO:0031543 peptidyl-proline dioxygenase activity 3.16692983298825e-07 13 117 5 0.0427350427350427 0.384615384615385
GO:MF GO:0016706 2-oxoglutarate-dependent dioxygenase activity 5.07934880417576e-07 48 117 7 0.0598290598290598 0.145833333333333
GO:MF GO:0050840 extracellular matrix binding 5.56731381607906e-07 56 59 6 0.101694915254237 0.107142857142857
GO:MF GO:0046872 metal ion binding 2.59376605574145e-06 4260 53 30 0.566037735849057 0.00704225352112676
GO:MF GO:0005509 calcium ion binding 3.69241137510863e-06 721 39 11 0.282051282051282 0.0152565880721221
GO:MF GO:0043169 cation binding 3.81840130529532e-06 4351 53 30 0.566037735849057 0.00689496667432774
GO:MF GO:0004720 protein-lysine 6-oxidase activity 4.10653622674823e-06 5 52 3 0.0576923076923077 0.6
GO:MF GO:0008201 heparin binding 4.3145958413725e-06 168 16 5 0.3125 0.0297619047619048
GO:MF GO:0030023 extracellular matrix constituent conferring elasticity 5.5464704175142e-06 9 133 4 0.0300751879699248 0.444444444444444
GO:MF GO:0097493 structural molecule activity conferring elasticity 1.37418728194195e-05 11 133 4 0.0300751879699248 0.363636363636364
GO:MF GO:0004222 metalloendopeptidase activity 1.95910330521484e-05 108 135 8 0.0592592592592593 0.0740740740740741
GO:MF GO:0005539 glycosaminoglycan binding 2.0335548132534e-05 238 16 5 0.3125 0.0210084033613445
GO:MF GO:1901681 sulfur compound binding 3.25527698072204e-05 264 16 5 0.3125 0.0189393939393939
GO:MF GO:0004656 procollagen-proline 4-dioxygenase activity 3.43913556622012e-05 5 117 3 0.0256410256410256 0.6
GO:MF GO:0051213 dioxygenase activity 3.43913556622012e-05 96 117 7 0.0598290598290598 0.0729166666666667
GO:MF GO:0030246 carbohydrate binding 3.71049474417212e-05 275 80 9 0.1125 0.0327272727272727
GO:MF GO:0048029 monosaccharide binding 7.37204594246126e-05 71 117 6 0.0512820512820513 0.0845070422535211
GO:MF GO:0016705 oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen 9.66659883802141e-05 167 80 7 0.0875 0.0419161676646707
GO:MF GO:0016641 oxidoreductase activity, acting on the CH-NH2 group of donors, oxygen as acceptor 0.000140649536255447 16 52 3 0.0576923076923077 0.1875
GO:MF GO:0031545 peptidyl-proline 4-dioxygenase activity 0.000233273003669925 9 117 3 0.0256410256410256 0.333333333333333
GO:MF GO:0043167 ion binding 0.000233273003669925 6057 59 35 0.593220338983051 0.00577843817071157
GO:MF GO:0043236 laminin binding 0.000233473389497997 28 109 4 0.036697247706422 0.142857142857143
GO:MF GO:0016638 oxidoreductase activity, acting on the CH-NH2 group of donors 0.000252513591894233 20 52 3 0.0576923076923077 0.15
GO:MF GO:0005506 iron ion binding 0.00052784728892145 155 117 7 0.0598290598290598 0.0451612903225806
GO:MF GO:0008237 metallopeptidase activity 0.000635631181222559 188 135 8 0.0592592592592593 0.0425531914893617
GO:MF GO:0043177 organic acid binding 0.000956057864018377 120 117 6 0.0512820512820513 0.05
GO:MF GO:0061134 peptidase regulator activity 0.00107167934615288 224 22 4 0.181818181818182 0.0178571428571429
GO:MF GO:0046914 transition metal ion binding 0.00120025284616294 1111 135 20 0.148148148148148 0.018001800180018
GO:MF GO:0019899 enzyme binding 0.00122875980279366 2074 4 4 1 0.00192864030858245
GO:MF GO:0005102 signaling receptor binding 0.00187392265041438 1672 61 15 0.245901639344262 0.00897129186602871
GO:MF GO:0005507 copper ion binding 0.00213315744173615 61 97 4 0.0412371134020619 0.0655737704918033
GO:MF GO:0016491 oxidoreductase activity 0.00244731691020902 771 117 14 0.11965811965812 0.0181582360570687
GO:MF GO:0019842 vitamin binding 0.00254781123514807 149 117 6 0.0512820512820513 0.0402684563758389
GO:MF GO:0015026 coreceptor activity 0.00297196030152621 47 58 3 0.0517241379310345 0.0638297872340425
GO:MF GO:0001968 fibronectin binding 0.00391031493179987 28 109 3 0.0275229357798165 0.107142857142857
GO:MF GO:0001618 virus receptor activity 0.00513482459727777 76 44 3 0.0681818181818182 0.0394736842105263
GO:MF GO:0140272 exogenous protein binding 0.00524679250370532 77 44 3 0.0681818181818182 0.038961038961039
GO:MF GO:0004866 endopeptidase inhibitor activity 0.00637145177202347 176 47 4 0.0851063829787234 0.0227272727272727
GO:MF GO:0030414 peptidase inhibitor activity 0.00710155891054283 182 47 4 0.0851063829787234 0.021978021978022
GO:MF GO:0061135 endopeptidase regulator activity 0.00788234419376543 188 47 4 0.0851063829787234 0.0212765957446809
GO:MF GO:0031406 carboxylic acid binding 0.00859394267252169 194 117 6 0.0512820512820513 0.0309278350515464
GO:MF GO:0004175 endopeptidase activity 0.00975353205864329 450 135 10 0.0740740740740741 0.0222222222222222
GO:MF GO:0140096 catalytic activity, acting on a protein 0.0132916573253906 2332 141 30 0.212765957446809 0.0128644939965695
GO:MF GO:0005515 protein binding 0.023200111574596 14767 56 52 0.928571428571429 0.00352136520620302
GO:MF GO:0005048 signal sequence binding 0.0236658218735041 49 131 3 0.0229007633587786 0.0612244897959184
GO:MF GO:0042802 identical protein binding 0.0236658218735041 2067 4 3 0.75 0.00145137880986938
GO:MF GO:0098631 cell adhesion mediator activity 0.0240089168482017 58 112 3 0.0267857142857143 0.0517241379310345
GO:MF GO:0016853 isomerase activity 0.0359223856392523 169 90 4 0.0444444444444444 0.0236686390532544
GO:MF GO:0004857 enzyme inhibitor activity 0.0375277748163652 385 22 3 0.136363636363636 0.00779220779220779
GO:MF GO:0008233 peptidase activity 0.0497212232546269 646 59 6 0.101694915254237 0.00928792569659443
HP HP:0006256 Abnormality of hand joint mobility 1.50975676927645e-11 29 16 8 0.5 0.275862068965517
HP HP:0006094 Finger joint hypermobility 1.50975676927645e-11 28 16 8 0.5 0.285714285714286
HP HP:0025019 Arterial rupture 5.93421968221814e-11 8 7 5 0.714285714285714 0.625
HP HP:0000592 Blue sclerae 1.95176268056052e-10 81 27 11 0.407407407407407 0.135802469135802
HP HP:0030009 Cervical insufficiency 9.5159572975359e-10 4 7 4 0.571428571428571 1
HP HP:0000591 Abnormal sclera morphology 1.78283922743719e-09 102 27 11 0.407407407407407 0.107843137254902
HP HP:0000993 Molluscoid pseudotumors 2.89108872016625e-09 6 67 6 0.0895522388059701 1
HP HP:0000974 Hyperextensible skin 4.68478342002991e-09 62 17 8 0.470588235294118 0.129032258064516
HP HP:0000977 Soft skin 4.68478342002991e-09 35 17 7 0.411764705882353 0.2
HP HP:0001073 Cigarette-paper scars 5.94110930507684e-09 6 7 4 0.571428571428571 0.666666666666667
HP HP:0100823 Genital hernia 5.94110930507684e-09 6 7 4 0.571428571428571 0.666666666666667
HP HP:0000139 Uterine prolapse 5.94110930507684e-09 6 7 4 0.571428571428571 0.666666666666667
HP HP:0000015 Bladder diverticulum 6.4062825396768e-09 22 7 5 0.714285714285714 0.227272727272727
HP HP:0001382 Joint hypermobility 1.18350261041122e-08 304 25 14 0.56 0.0460526315789474
HP HP:0004872 Incisional hernia 1.64943259823956e-08 4 16 4 0.25 1
HP HP:0002645 Wormian bones 1.77259418781914e-08 49 92 12 0.130434782608696 0.244897959183673
HP HP:0001788 Premature rupture of membranes 1.77259418781914e-08 9 51 6 0.117647058823529 0.666666666666667
HP HP:0005294 Arterial dissection 1.84636667602112e-08 8 7 4 0.571428571428571 0.5
HP HP:0001027 Soft, doughy skin 2.13968595763933e-08 11 17 5 0.294117647058824 0.454545454545455
HP HP:0001030 Fragile skin 2.13968595763933e-08 30 7 5 0.714285714285714 0.166666666666667
HP HP:0001075 Atrophic scars 2.13968595763933e-08 30 7 5 0.714285714285714 0.166666666666667
HP HP:0012888 Abnormality of the uterine cervix 2.71773851972922e-08 9 7 4 0.571428571428571 0.444444444444444
HP HP:0006149 Increased laxity of fingers 2.95294485842312e-08 5 14 4 0.285714285714286 0.8
HP HP:0004947 Arteriovenous fistula 6.51774198238365e-08 11 7 4 0.571428571428571 0.363636363636364
HP HP:0001384 Abnormality of the hip joint 6.57047778984826e-08 295 17 11 0.647058823529412 0.0372881355932203
HP HP:0005072 Hyperextensibility at wrists 7.82268136192989e-08 6 14 4 0.285714285714286 0.666666666666667
HP HP:0005262 Abnormality of the synovia 8.41593671637486e-08 304 17 11 0.647058823529412 0.0361842105263158
HP HP:0002827 Hip dislocation 1.09813063874372e-07 228 17 10 0.588235294117647 0.043859649122807
HP HP:0010749 Blepharochalasis 1.66574345220792e-07 6 17 4 0.235294117647059 0.666666666666667
HP HP:0025014 Subcutaneous spheroids 1.77869101819775e-07 3 7 3 0.428571428571429 1
HP HP:0001058 Poor wound healing 2.50500024775127e-07 22 14 5 0.357142857142857 0.227272727272727
HP HP:0003834 Shoulder dislocation 2.68875889217583e-07 16 7 4 0.571428571428571 0.25
HP HP:0001373 Joint dislocation 2.85400766906714e-07 347 17 11 0.647058823529412 0.031700288184438
HP HP:0010647 Abnormal elasticity of skin 2.87637740200109e-07 181 17 9 0.529411764705882 0.0497237569060773
HP HP:0025487 Abnormality of bladder morphology 3.10476859493064e-07 55 7 5 0.714285714285714 0.0909090909090909
HP HP:0030311 Lower extremity joint dislocation 4.02619923234715e-07 267 17 10 0.588235294117647 0.0374531835205993
HP HP:0005988 Congenital muscular torticollis 4.59282306041276e-07 9 14 4 0.285714285714286 0.444444444444444
HP HP:0001388 Joint laxity 5.57614981327739e-07 205 27 11 0.407407407407407 0.0536585365853659
HP HP:0025509 Piezogenic pedal papules 5.57614981327739e-07 4 7 3 0.428571428571429 0.75
HP HP:0030095 Reduced muscle collagen VI 6.28894324291347e-07 3 11 3 0.272727272727273 1
HP HP:0008067 Abnormally lax or hyperextensible skin 7.44451074785675e-07 139 17 8 0.470588235294118 0.0575539568345324
HP HP:0000703 Dentinogenesis imperfecta 7.61672222173037e-07 13 67 6 0.0895522388059701 0.461538461538462
HP HP:0002815 Abnormality of the knee 9.42160727755886e-07 323 16 10 0.625 0.0309597523219814
HP HP:0100297 Increased endomysial connective tissue 1.00790709223232e-06 11 14 4 0.285714285714286 0.363636363636364
HP HP:0002616 Aortic root aneurysm 1.03562512829458e-06 73 7 5 0.714285714285714 0.0684931506849315
HP HP:0004944 Dilatation of the cerebral artery 1.1067893399922e-06 38 23 6 0.260869565217391 0.157894736842105
HP HP:0010299 Abnormality of dentin 1.17723865150682e-06 14 67 6 0.0895522388059701 0.428571428571429
HP HP:0004334 Dermal atrophy 1.24917797637137e-06 77 7 5 0.714285714285714 0.0649350649350649
HP HP:0002644 Abnormality of pelvic girdle bone morphology 1.24917797637137e-06 536 17 12 0.705882352941177 0.0223880597014925
HP HP:0001762 Talipes equinovarus 1.31299352273583e-06 293 14 9 0.642857142857143 0.0307167235494881
HP HP:0031869 Recurrent joint dislocation 2.04822051176681e-06 7 6 3 0.5 0.428571428571429
HP HP:0003771 Pulp stones 2.04822051176681e-06 6 7 3 0.428571428571429 0.5
HP HP:0001883 Talipes 2.07187190680216e-06 358 16 10 0.625 0.0279329608938547
HP HP:0001704 Tricuspid valve prolapse 2.19753153130881e-06 12 16 4 0.25 0.333333333333333
HP HP:0001634 Mitral valve prolapse 2.19753153130881e-06 88 7 5 0.714285714285714 0.0568181818181818
HP HP:0010511 Long toe 2.21278969209253e-06 32 16 5 0.3125 0.15625
HP HP:0005656 Positional foot deformity 2.21278969209253e-06 363 16 10 0.625 0.0275482093663912
HP HP:0010750 Dermatochalasis 3.08589411083133e-06 7 7 3 0.428571428571429 0.428571428571429
HP HP:0006243 Phalangeal dislocation 3.08589411083133e-06 7 7 3 0.428571428571429 0.428571428571429
HP HP:0009113 Diaphragmatic weakness 3.08589411083133e-06 15 14 4 0.285714285714286 0.266666666666667
HP HP:0001387 Joint stiffness 3.08589411083133e-06 175 17 8 0.470588235294118 0.0457142857142857
HP HP:0100491 Abnormality of lower limb joint 3.16642481244618e-06 594 17 12 0.705882352941177 0.0202020202020202
HP HP:0012727 Thoracic aortic aneurysm 3.48804322178308e-06 99 7 5 0.714285714285714 0.0505050505050505
HP HP:0006367 Crumpled long bones 3.51807470171332e-06 6 42 4 0.0952380952380952 0.666666666666667
HP HP:0009073 Progressive proximal muscle weakness 3.72937986022224e-06 16 14 4 0.285714285714286 0.25
HP HP:0010648 Dermal translucency 4.19574417177186e-06 15 4 3 0.75 0.2
HP HP:0003272 Abnormality of the hip bone 4.36761899280276e-06 480 17 11 0.647058823529412 0.0229166666666667
HP HP:0008081 Pes valgus 4.56665932010488e-06 38 16 5 0.3125 0.131578947368421
HP HP:0001238 Slender finger 4.57108298294336e-06 124 24 8 0.333333333333333 0.0645161290322581
HP HP:0001633 Abnormal mitral valve morphology 5.85926299498326e-06 112 7 5 0.714285714285714 0.0446428571428571
HP HP:0000978 Bruising susceptibility 5.89797613080333e-06 135 23 8 0.347826086956522 0.0592592592592593
HP HP:0003179 Protrusio acetabuli 6.78899801407177e-06 10 27 4 0.148148148148148 0.4
HP HP:0001270 Motor delay 7.62709909943973e-06 651 17 12 0.705882352941177 0.0184331797235023
HP HP:0031364 Ecchymosis 7.7704627853382e-06 43 7 4 0.571428571428571 0.0930232558139535
HP HP:0003741 Congenital muscular dystrophy 8.43048791312356e-06 20 14 4 0.285714285714286 0.2
HP HP:0007502 Follicular hyperkeratosis 8.43048791312356e-06 20 14 4 0.285714285714286 0.2
HP HP:0001065 Striae distensae 9.54157625123459e-06 18 16 4 0.25 0.222222222222222
HP HP:0002650 Scoliosis 1.04932137459024e-05 941 27 18 0.666666666666667 0.0191285866099894
HP HP:0025323 Abnormal arterial physiology 1.08117342066746e-05 130 7 5 0.714285714285714 0.0384615384615385
HP HP:0010754 Abnormality of the temporomandibular joint 1.08117342066746e-05 11 7 3 0.428571428571429 0.272727272727273
HP HP:0006460 Increased laxity of ankles 1.08117342066746e-05 7 11 3 0.272727272727273 0.428571428571429
HP HP:0006705 Abnormal atrioventricular valve morphology 1.1442549069536e-05 132 7 5 0.714285714285714 0.0378787878787879
HP HP:0009145 Abnormal cerebral artery morphology 1.1442549069536e-05 61 23 6 0.260869565217391 0.0983606557377049
HP HP:0001622 Premature birth 1.28820414553483e-05 145 17 7 0.411764705882353 0.0482758620689655
HP HP:0009811 Abnormality of the elbow 1.29321884424224e-05 237 16 8 0.5 0.0337552742616034
HP HP:0000987 Atypical scarring of skin 1.34872886748711e-05 138 7 5 0.714285714285714 0.036231884057971
HP HP:0004942 Aortic aneurysm 1.34872886748711e-05 138 7 5 0.714285714285714 0.036231884057971
HP HP:0001892 Abnormal bleeding 1.48204841329747e-05 439 8 7 0.875 0.0159453302961276
HP HP:0020152 Distal joint laxity 1.48864466830374e-05 8 11 3 0.272727272727273 0.375
HP HP:0100026 Arteriovenous malformation 1.54191690814248e-05 54 7 4 0.571428571428571 0.0740740740740741
HP HP:0002758 Osteoarthritis 1.77019761385135e-05 56 7 4 0.571428571428571 0.0714285714285714
HP HP:0003713 Muscle fiber necrosis 2.16101066802317e-05 9 11 3 0.272727272727273 0.333333333333333
HP HP:0008065 Aplasia/Hypoplasia of the skin 2.25819969450412e-05 161 17 7 0.411764705882353 0.0434782608695652
HP HP:0100699 Scarring 2.41080131772166e-05 159 7 5 0.714285714285714 0.0314465408805031
HP HP:0100659 Abnormality of the cerebral vasculature 2.54806368614626e-05 269 8 6 0.75 0.0223048327137546
HP HP:0010674 Abnormality of the curvature of the vertebral column 2.64554290070706e-05 1014 27 18 0.666666666666667 0.0177514792899408
HP HP:0031365 Macular purpura 2.69180635363517e-05 63 7 4 0.571428571428571 0.0634920634920635
HP HP:0001787 Abnormal delivery 2.79923084059811e-05 77 22 6 0.272727272727273 0.0779220779220779
HP HP:0000926 Platyspondyly 2.89713493017858e-05 113 72 11 0.152777777777778 0.0973451327433628
HP HP:0000023 Inguinal hernia 2.9467208240591e-05 241 23 9 0.391304347826087 0.037344398340249
HP HP:0002617 Vascular dilatation 4.73662099306623e-05 185 7 5 0.714285714285714 0.027027027027027
HP HP:0001063 Acrocyanosis 4.73662099306623e-05 19 7 3 0.428571428571429 0.157894736842105
HP HP:0002036 Hiatus hernia 5.74786679231482e-05 28 17 4 0.235294117647059 0.142857142857143
HP HP:0006466 Ankle flexion contracture 7.1908616029589e-05 41 27 5 0.185185185185185 0.121951219512195
HP HP:0001482 Subcutaneous nodule 8.23436180501644e-05 85 7 4 0.571428571428571 0.0470588235294118
HP HP:0001933 Subcutaneous hemorrhage 8.65591825347705e-05 211 7 5 0.714285714285714 0.023696682464455
HP HP:0003043 Abnormal shoulder morphology 9.58994139404803e-05 89 14 5 0.357142857142857 0.0561797752808989
HP HP:0002877 Nocturnal hypoventilation 9.79428524791052e-05 15 11 3 0.272727272727273 0.2
HP HP:0007126 Proximal amyotrophy 9.966309570653e-05 40 14 4 0.285714285714286 0.1
HP HP:0030310 Upper extremity joint dislocation 9.966309570653e-05 90 7 4 0.571428571428571 0.0444444444444444
HP HP:0009810 Abnormality of upper limb joint 0.000118320692925034 454 16 9 0.5625 0.0198237885462555
HP HP:0002035 Rectal prolapse 0.000127992029134718 27 7 3 0.428571428571429 0.111111111111111
HP HP:0002953 Vertebral compression fractures 0.000135005816052812 30 114 7 0.0614035087719298 0.233333333333333
HP HP:0002812 Coxa vara 0.000144940431585818 57 4 3 0.75 0.0526315789473684
HP HP:0001181 Adducted thumb 0.000149748415539492 85 16 5 0.3125 0.0588235294117647
HP HP:0001702 Abnormal tricuspid valve morphology 0.000151019591043483 39 16 4 0.25 0.102564102564103
HP HP:0100679 Lack of skin elasticity 0.000151019591043483 39 16 4 0.25 0.102564102564103
HP HP:0200036 Skin nodule 0.000157024177380946 103 7 4 0.571428571428571 0.0388349514563107
HP HP:0100540 Palpebral edema 0.000157024177380946 37 17 4 0.235294117647059 0.108108108108108
HP HP:0000979 Purpura 0.000160685836676104 104 7 4 0.571428571428571 0.0384615384615385
HP HP:0002105 Hemoptysis 0.000162558030461064 59 23 5 0.217391304347826 0.0847457627118644
HP HP:0009763 Limb pain 0.000162558030461064 30 7 3 0.428571428571429 0.1
HP HP:0030163 Abnormal vascular physiology 0.000165025222113434 248 7 5 0.714285714285714 0.0201612903225806
HP HP:0000444 Convex nasal ridge 0.000189091143858319 64 4 3 0.75 0.046875
HP HP:0002808 Kyphosis 0.000234846878517074 420 27 11 0.407407407407407 0.0261904761904762
HP HP:0000473 Torticollis 0.000248578746188599 52 14 4 0.285714285714286 0.0769230769230769
HP HP:0001653 Mitral regurgitation 0.000250591490818512 118 7 4 0.571428571428571 0.0338983050847458
HP HP:0000963 Thin skin 0.000260515259905087 72 4 3 0.75 0.0416666666666667
HP HP:0003306 Spinal rigidity 0.000262596188306093 53 14 4 0.285714285714286 0.0754716981132075
HP HP:0007495 Prematurely aged appearance 0.000277581207414856 123 7 4 0.571428571428571 0.032520325203252
HP HP:0001001 Abnormality of subcutaneous fat tissue 0.000277581207414856 44 17 4 0.235294117647059 0.0909090909090909
HP HP:0003010 Prolonged bleeding time 0.000277581207414856 44 17 4 0.235294117647059 0.0909090909090909
HP HP:0003323 Progressive muscle weakness 0.000277581207414856 54 14 4 0.285714285714286 0.0740740740740741
HP HP:0001654 Abnormal heart valve morphology 0.000277581207414856 279 7 5 0.714285714285714 0.017921146953405
HP HP:0003083 Dislocated radial head 0.000277581207414856 37 7 3 0.428571428571429 0.0810810810810811
HP HP:0011061 Abnormality of dental structure 0.000277581207414856 280 7 5 0.714285714285714 0.0178571428571429
HP HP:0004299 Hernia of the abdominal wall 0.00029957715736839 404 24 10 0.416666666666667 0.0247524752475248
HP HP:0031105 Abnormal uterus morphology 0.000308780360900116 127 7 4 0.571428571428571 0.031496062992126
HP HP:0001763 Pes planus 0.000314202993377028 290 7 5 0.714285714285714 0.0172413793103448
HP HP:0010866 Abdominal wall defect 0.00032044064679583 408 24 10 0.416666666666667 0.0245098039215686
HP HP:0011006 Abnormal morphology of the musculature of the neck 0.000321618353568197 57 14 4 0.285714285714286 0.0701754385964912
HP HP:0005918 Abnormal finger phalanx morphology 0.000322977776750164 631 17 10 0.588235294117647 0.0158478605388273
HP HP:0003995 Abnormality of the radial head 0.000329641303495883 40 7 3 0.428571428571429 0.075
HP HP:0006479 Abnormality of the dental pulp 0.000329641303495883 40 7 3 0.428571428571429 0.075
HP HP:0003312 Abnormal form of the vertebral bodies 0.000329641303495883 292 53 13 0.245283018867925 0.0445205479452055
HP HP:0008180 Mildly elevated creatine kinase 0.000329641303495883 58 14 4 0.285714285714286 0.0689655172413793
HP HP:0003557 Increased variability in muscle fiber diameter 0.000329641303495883 58 14 4 0.285714285714286 0.0689655172413793
HP HP:0002828 Multiple joint contractures 0.000329641303495883 58 14 4 0.285714285714286 0.0689655172413793
HP HP:0001376 Limitation of joint mobility 0.000333193017300303 367 17 8 0.470588235294118 0.0217983651226158
HP HP:0031481 Abnormal mitral valve physiology 0.000333193017300303 132 7 4 0.571428571428571 0.0303030303030303
HP HP:0001278 Orthostatic hypotension 0.000342291751401581 41 7 3 0.428571428571429 0.0731707317073171
HP HP:0001187 Hyperextensibility of the finger joints 0.000343379942528564 17 16 3 0.1875 0.176470588235294
HP HP:0030089 Abnormal muscle fiber protein expression 0.000343379942528564 25 11 3 0.272727272727273 0.12
HP HP:0002761 Generalized joint laxity 0.000361595611843912 42 7 3 0.428571428571429 0.0714285714285714
HP HP:0004326 Cachexia 0.000361595611843912 60 14 4 0.285714285714286 0.0666666666666667
HP HP:0001367 Abnormal joint morphology 0.000365603188610635 999 7 7 1 0.00700700700700701
HP HP:0030962 Abnormal morphology of the great vessels 0.000366055504745221 575 7 6 0.857142857142857 0.0104347826086957
HP HP:0004349 Reduced bone mineral density 0.000374981596910772 452 27 11 0.407407407407407 0.0243362831858407
HP HP:0012084 Abnormality of skeletal muscle fiber size 0.000374981596910772 61 14 4 0.285714285714286 0.0655737704918033
HP HP:0100541 Femoral hernia 0.000396637001213621 17 17 3 0.176470588235294 0.176470588235294
HP HP:0100744 Abnormality of the humeroradial joint 0.000425522233134359 45 7 3 0.428571428571429 0.0666666666666667
HP HP:0001679 Abnormal aortic morphology 0.000432655170351455 319 7 5 0.714285714285714 0.0156739811912226
HP HP:0000925 Abnormality of the vertebral column 0.000444434909584105 1304 11 10 0.909090909090909 0.00766871165644172
HP HP:0001386 Joint swelling 0.000508649922532514 48 7 3 0.428571428571429 0.0625
HP HP:0001197 Abnormality of prenatal development or birth 0.000526031799095371 846 17 11 0.647058823529412 0.0130023640661939
HP HP:0002107 Pneumothorax 0.000543841938038384 40 23 4 0.173913043478261 0.1
HP HP:0001533 Slender build 0.000547241721964532 30 11 3 0.272727272727273 0.1
HP HP:0002999 Patellar dislocation 0.000584789490760236 51 7 3 0.428571428571429 0.0588235294117647
HP HP:0031650 Abnormal atrioventricular valve physiology 0.000584789490760236 157 7 4 0.571428571428571 0.0254777070063694
HP HP:0008780 Congenital bilateral hip dislocation 0.000584789490760236 7 51 3 0.0588235294117647 0.428571428571429
HP HP:0000938 Osteopenia 0.000597947924259359 236 27 8 0.296296296296296 0.0338983050847458
HP HP:0004298 Abnormality of the abdominal wall 0.000603670584725458 449 24 10 0.416666666666667 0.022271714922049
HP HP:0012450 Chronic constipation 0.000606980018352743 52 7 3 0.428571428571429 0.0576923076923077
HP HP:0032153 Joint subluxation 0.000606980018352743 20 17 3 0.176470588235294 0.15
HP HP:0003700 Generalized amyotrophy 0.000620427940579695 71 14 4 0.285714285714286 0.0563380281690141
HP HP:0006380 Knee flexion contracture 0.000649527947096427 72 14 4 0.285714285714286 0.0555555555555556
HP HP:0003042 Elbow dislocation 0.000656386699317646 81 24 5 0.208333333333333 0.0617283950617284
HP HP:0011799 Abnormality of facial soft tissue 0.000658871218310289 413 17 8 0.470588235294118 0.0193704600484262
HP HP:0005743 Avascular necrosis of the capital femoral epiphysis 0.000681381806082871 21 17 3 0.176470588235294 0.142857142857143
HP HP:0002987 Elbow flexion contracture 0.000698869503373079 74 84 8 0.0952380952380952 0.108108108108108
HP HP:0100539 Periorbital edema 0.000706599287562595 60 17 4 0.235294117647059 0.0666666666666667
HP HP:0002817 Abnormality of the upper limb 0.000753550412142399 1395 11 10 0.909090909090909 0.00716845878136201
HP HP:0001374 Congenital hip dislocation 0.000771096676400404 76 14 4 0.285714285714286 0.0526315789473684
HP HP:0003560 Muscular dystrophy 0.000805408968657176 77 14 4 0.285714285714286 0.051948051948052
HP HP:0000277 Abnormality of the mandible 0.000806374424784624 897 25 14 0.56 0.0156075808249721
HP HP:0003508 Proportionate short stature 0.000819083106010111 125 17 5 0.294117647058824 0.04
HP HP:0012499 Descending aortic dissection 0.000850463689190171 17 23 3 0.130434782608696 0.176470588235294
HP HP:0100790 Hernia 0.000883727759009189 475 24 10 0.416666666666667 0.0210526315789474
HP HP:0000565 Esotropia 0.00090535670050988 137 16 5 0.3125 0.0364963503649635
HP HP:0006487 Bowing of the long bones 0.000954973276136841 241 53 11 0.207547169811321 0.045643153526971
HP HP:0012179 Craniofacial dystonia 0.000985459519371601 82 14 4 0.285714285714286 0.0487804878048781
HP HP:0002783 Recurrent lower respiratory tract infections 0.00102670875056058 109 11 4 0.363636363636364 0.036697247706422
HP HP:0002757 Recurrent fractures 0.00102670875056058 131 4 3 0.75 0.0229007633587786
HP HP:0004348 Abnormality of bone mineral density 0.00103738500510137 516 27 11 0.407407407407407 0.0213178294573643
HP HP:0002813 Abnormality of limb bone morphology 0.00109136707487424 1465 11 10 0.909090909090909 0.0068259385665529
HP HP:0020045 Esodeviation 0.00109136707487424 144 16 5 0.3125 0.0347222222222222
HP HP:0010500 Hyperextensibility of the knee 0.00109136707487424 27 16 3 0.1875 0.111111111111111
HP HP:0040068 Abnormality of limb bone 0.00109136707487424 1465 11 10 0.909090909090909 0.0068259385665529
HP HP:0001760 Abnormal foot morphology 0.00109211491576015 1215 7 7 1 0.00576131687242798
HP HP:0000282 Facial edema 0.00109211491576015 69 17 4 0.235294117647059 0.0579710144927536
HP HP:0001369 Arthritis 0.00115123895361348 196 7 4 0.571428571428571 0.0204081632653061
HP HP:0011729 Abnormality of joint mobility 0.00115940999606465 1095 27 16 0.592592592592593 0.0146118721461187
HP HP:0030791 Abnormal jaw morphology 0.00116612044945388 940 17 11 0.647058823529412 0.0117021276595745
HP HP:0003367 Abnormal femoral neck morphology 0.00121088960044975 141 4 3 0.75 0.0212765957446809
HP HP:0000014 Abnormality of the bladder 0.00128476004895731 421 7 5 0.714285714285714 0.0118764845605701
HP HP:0030972 Abnormal systemic blood pressure 0.0013088938316979 423 7 5 0.714285714285714 0.0118203309692671
HP HP:0000325 Triangular face 0.00135619825611887 119 92 10 0.108695652173913 0.0840336134453782
HP HP:0002018 Nausea 0.00137069537943018 73 7 3 0.428571428571429 0.0410958904109589
HP HP:0000883 Thin ribs 0.0014361057901858 44 53 5 0.0943396226415094 0.113636363636364
HP HP:0004373 Focal dystonia 0.00144119286390284 93 14 4 0.285714285714286 0.043010752688172
HP HP:0031784 Abnormal ascending aorta morphology 0.00144119286390284 21 23 3 0.130434782608696 0.142857142857143
HP HP:0004933 Ascending aortic dissection 0.00144119286390284 21 23 3 0.130434782608696 0.142857142857143
HP HP:0011004 Abnormal systemic arterial morphology 0.00144830330532653 435 7 5 0.714285714285714 0.0114942528735632
HP HP:0002359 Frequent falls 0.00148738737107008 94 14 4 0.285714285714286 0.0425531914893617
HP HP:0000130 Abnormality of the uterus 0.00148738737107008 213 7 4 0.571428571428571 0.0187793427230047
HP HP:0000765 Abnormal thorax morphology 0.00151801360701351 777 7 6 0.857142857142857 0.00772200772200772
HP HP:0003045 Abnormal patella morphology 0.00152677311344698 95 14 4 0.285714285714286 0.0421052631578947
HP HP:0032016 Abnormal sputum 0.00152677311344698 106 23 5 0.217391304347826 0.0471698113207547
HP HP:0003803 Type 1 muscle fiber predominance 0.001588419297511 47 11 3 0.272727272727273 0.0638297872340425
HP HP:0200034 Papule 0.001588419297511 78 7 3 0.428571428571429 0.0384615384615385
HP HP:0009122 Aplasia/hypoplasia affecting bones of the axial skeleton 0.00161263890915555 797 17 10 0.588235294117647 0.0125470514429109
HP HP:0100323 Juvenile aseptic necrosis 0.00161263890915555 30 17 3 0.176470588235294 0.1
HP HP:0000411 Protruding ear 0.00168624009080827 166 24 6 0.25 0.036144578313253
HP HP:0003366 Abnormal femoral neck/head morphology 0.00170262288784507 163 4 3 0.75 0.0184049079754601
HP HP:0033353 Abnormal blood vessel morphology 0.00172210812121557 799 7 6 0.857142857142857 0.00750938673341677
HP HP:0025015 Abnormal vascular morphology 0.00175313432180447 802 7 6 0.857142857142857 0.00748129675810474
HP HP:0012385 Camptodactyly 0.00181007635574275 266 16 6 0.375 0.0225563909774436
HP HP:0000098 Tall stature 0.00181428003384086 177 23 6 0.260869565217391 0.0338983050847458
HP HP:0005692 Joint hyperflexibility 0.00182407873018071 175 92 12 0.130434782608696 0.0685714285714286
HP HP:0011844 Abnormal appendicular skeleton morphology 0.00188349190776947 1575 11 10 0.909090909090909 0.00634920634920635
HP HP:0002791 Hypoventilation 0.00192630148020162 51 11 3 0.272727272727273 0.0588235294117647
HP HP:0001167 Abnormality of finger 0.00199103212088747 1008 17 11 0.647058823529412 0.0109126984126984
HP HP:0000940 Abnormal diaphysis morphology 0.00199431975360418 268 53 11 0.207547169811321 0.041044776119403
HP HP:0000961 Cyanosis 0.00199431975360418 86 7 3 0.428571428571429 0.0348837209302326
HP HP:0000286 Epicanthus 0.00203126510659587 476 7 5 0.714285714285714 0.0105042016806723
HP HP:0001324 Muscle weakness 0.00203126510659587 898 11 8 0.727272727272727 0.0089086859688196
HP HP:0001537 Umbilical hernia 0.00210780327194899 257 17 6 0.352941176470588 0.0233463035019455
HP HP:0100490 Camptodactyly of finger 0.00210780327194899 172 16 5 0.3125 0.0290697674418605
HP HP:0002093 Respiratory insufficiency 0.00211501645232649 547 16 8 0.5 0.0146252285191956
HP HP:0002315 Headache 0.0021279460656588 240 7 4 0.571428571428571 0.0166666666666667
HP HP:0000766 Abnormal sternum morphology 0.00215471598744979 382 27 9 0.333333333333333 0.0235602094240838
HP HP:0011843 Abnormality of musculoskeletal physiology 0.0021976623969709 1379 7 7 1 0.0050761421319797
HP HP:0000311 Round face 0.00221742577655105 93 16 4 0.25 0.043010752688172
HP HP:0000969 Edema 0.00222746621283411 489 7 5 0.714285714285714 0.0102249488752556
HP HP:0040070 Abnormal upper limb bone morphology 0.00222746621283411 406 8 5 0.625 0.0123152709359606
HP HP:0003330 Abnormal bone structure 0.00225714708979576 687 8 6 0.75 0.00873362445414847
HP HP:0011276 Vascular skin abnormality 0.00228960191904847 493 7 5 0.714285714285714 0.0101419878296146
HP HP:0001551 Abnormal umbilicus morphology 0.00228960191904847 263 17 6 0.352941176470588 0.0228136882129278
HP HP:0003307 Hyperlordosis 0.00229765068889603 177 16 5 0.3125 0.0282485875706215
HP HP:0001220 Interphalangeal joint contracture of finger 0.00229765068889603 177 16 5 0.3125 0.0282485875706215
HP HP:3000030 Abnormality of bony orbit of skull 0.0023545321575899 24 25 3 0.12 0.125
HP HP:0000586 Shallow orbits 0.0023545321575899 24 25 3 0.12 0.125
HP HP:0009124 Abnormal adipose tissue morphology 0.00243196372345383 192 4 3 0.75 0.015625
HP HP:0002979 Bowing of the legs 0.00243196372345383 192 4 3 0.75 0.015625
HP HP:0010529 Echolalia 0.00243196372345383 36 17 3 0.176470588235294 0.0833333333333333
HP HP:0030044 Flexion contracture of digit 0.00252458468351814 289 16 6 0.375 0.0207612456747405
HP HP:0002034 Abnormal rectum morphology 0.00267128362746397 98 7 3 0.428571428571429 0.0306122448979592
HP HP:0003510 Severe short stature 0.00268431452625165 93 17 4 0.235294117647059 0.043010752688172
HP HP:0032012 Heterotropia 0.00278633188524446 186 16 5 0.3125 0.0268817204301075
HP HP:0002659 Increased susceptibility to fractures 0.00281153467862128 203 4 3 0.75 0.0147783251231527
HP HP:0001155 Abnormality of the hand 0.00288723071064145 1276 11 9 0.818181818181818 0.00705329153605016
HP HP:0003458 EMG: myopathic abnormalities 0.00292213049473856 118 14 4 0.285714285714286 0.0338983050847458
HP HP:0002647 Aortic dissection 0.00292213049473856 31 51 4 0.0784313725490196 0.129032258064516
HP HP:0000347 Micrognathia 0.0029302973699507 697 17 9 0.529411764705882 0.0129124820659971
HP HP:0006261 Abnormal phalangeal joint morphology of the hand 0.00300351572886665 190 16 5 0.3125 0.0263157894736842
HP HP:0009118 Aplasia/Hypoplasia of the mandible 0.0030323968382859 701 17 9 0.529411764705882 0.0128388017118402
HP HP:0002814 Abnormality of the lower limb 0.0030323968382859 1465 7 7 1 0.00477815699658703
HP HP:0003468 Abnormal vertebral morphology 0.00305110719875938 406 27 9 0.333333333333333 0.0221674876847291
HP HP:0003324 Generalized muscle weakness 0.00305110719875938 120 14 4 0.285714285714286 0.0333333333333333
HP HP:0002170 Intracranial hemorrhage 0.00308069441078038 129 23 5 0.217391304347826 0.0387596899224806
HP HP:0011119 Abnormality of the nasal dorsum 0.00308069441078038 212 4 3 0.75 0.0141509433962264
HP HP:0001072 Thickened skin 0.00308101427772723 405 17 7 0.411764705882353 0.0172839506172839
HP HP:0002615 Hypotension 0.00309234669254007 105 7 3 0.428571428571429 0.0285714285714286
HP HP:0011849 Abnormal bone ossification 0.00319308629609533 607 27 11 0.407407407407407 0.0181219110378913
HP HP:0040069 Abnormal lower limb bone morphology 0.00326612466169853 649 4 4 1 0.0061633281972265
HP HP:0009116 Aplasia/Hypoplasia involving bones of the skull 0.00326612466169853 711 17 9 0.529411764705882 0.0126582278481013
HP HP:0011025 Abnormal cardiovascular system physiology 0.00326612466169853 1147 8 7 0.875 0.00610287707061901
HP HP:0012785 Flexion contracture of finger 0.00330125971011664 196 16 5 0.3125 0.0255102040816327
HP HP:0012332 Abnormal autonomic nervous system physiology 0.00335374909926164 109 7 3 0.428571428571429 0.0275229357798165
HP HP:0002996 Limited elbow movement 0.00340080293207303 125 14 4 0.285714285714286 0.032
HP HP:0003677 Slowly progressive 0.00340207105753186 164 11 4 0.363636363636364 0.024390243902439
HP HP:0001334 Communicating hydrocephalus 0.00345914887408423 17 42 3 0.0714285714285714 0.176470588235294
HP HP:0003028 Abnormality of the ankles 0.00355643430263916 127 14 4 0.285714285714286 0.031496062992126
HP HP:0011032 Abnormality of fluid regulation 0.00369272592437073 562 7 5 0.714285714285714 0.00889679715302491
HP HP:0000002 Abnormality of body height 0.0037983281678854 1335 11 9 0.818181818181818 0.00674157303370787
HP HP:0002138 Subarachnoid hemorrhage 0.0037983281678854 32 23 3 0.130434782608696 0.09375
HP HP:0031653 Abnormal heart valve physiology 0.00390687973024014 295 7 4 0.571428571428571 0.0135593220338983
HP HP:0011821 Abnormality of facial skeleton 0.00409511960460195 1115 17 11 0.647058823529412 0.00986547085201794
HP HP:0002981 Abnormality of the calf 0.00420255248297985 242 4 3 0.75 0.012396694214876
HP HP:0002823 Abnormality of femur morphology 0.00420255248297985 242 4 3 0.75 0.012396694214876
HP HP:0001871 Abnormality of blood and blood-forming tissues 0.00420255248297985 1201 8 7 0.875 0.00582847626977519
HP HP:0011329 Abnormality of cranial sutures 0.00438883827222344 287 92 15 0.16304347826087 0.0522648083623693
HP HP:0009115 Aplasia/hypoplasia involving the skeleton 0.00483806001776344 1050 5 5 1 0.00476190476190476
HP HP:0000278 Retrognathia 0.00516415327081936 261 4 3 0.75 0.0114942528735632
HP HP:0003170 Abnormal acetabulum morphology 0.00530080668969017 71 27 4 0.148148148148148 0.0563380281690141
HP HP:0003325 Limb-girdle muscle weakness 0.00537812778294864 79 11 3 0.272727272727273 0.0379746835443038
HP HP:0000678 Dental crowding 0.00552415245837322 85 23 4 0.173913043478261 0.0470588235294118
HP HP:0003199 Decreased muscle mass 0.00564021079742085 54 16 3 0.1875 0.0555555555555556
HP HP:0009473 Joint contracture of the hand 0.00570333198936477 225 16 5 0.3125 0.0222222222222222
HP HP:0000481 Abnormal cornea morphology 0.00575043941768909 625 7 5 0.714285714285714 0.008
HP HP:0012378 Fatigue 0.00594994482637152 335 7 4 0.571428571428571 0.0119402985074627
HP HP:0001780 Abnormality of toe 0.00618444636720681 616 17 8 0.470588235294118 0.012987012987013
HP HP:0002747 Respiratory insufficiency due to muscle weakness 0.00619556360893993 84 11 3 0.272727272727273 0.0357142857142857
HP HP:0001291 Abnormal cranial nerve morphology 0.00628381519343472 269 14 5 0.357142857142857 0.0185873605947955
HP HP:0003549 Abnormality of connective tissue 0.00671105774125829 1307 27 16 0.592592592592593 0.0122417750573833
HP HP:0001519 Disproportionate tall stature 0.00687501756866362 53 67 5 0.0746268656716418 0.0943396226415094
HP HP:0003394 Muscle spasm 0.00752451579463934 150 7 3 0.428571428571429 0.02
HP HP:0100807 Long fingers 0.00789727771472703 237 24 6 0.25 0.0253164556962025
HP HP:0005750 Contractures of the joints of the lower limbs 0.00792877212455209 162 14 4 0.285714285714286 0.0246913580246914
HP HP:0007392 Excessive wrinkled skin 0.00842891887720345 33 67 4 0.0597014925373134 0.121212121212121
HP HP:0000767 Pectus excavatum 0.00848309820733385 253 23 6 0.260869565217391 0.0237154150197628
HP HP:0002829 Arthralgia 0.00884753549238526 161 7 3 0.428571428571429 0.0186335403726708
HP HP:0004347 Weakness of muscles of respiration 0.00884753549238526 97 11 3 0.272727272727273 0.0309278350515464
HP HP:0010936 Abnormality of the lower urinary tract 0.00902378587143604 701 7 5 0.714285714285714 0.00713266761768902
HP HP:0000006 Autosomal dominant inheritance 0.00920376604456606 1774 7 7 1 0.00394588500563698
HP HP:0040064 Abnormality of limbs 0.0094740421113139 2001 8 8 1 0.00399800099950025
HP HP:0000962 Hyperkeratosis 0.0094758380568129 241 17 5 0.294117647058824 0.020746887966805
HP HP:0001319 Neonatal hypotonia 0.0107190828651002 179 14 4 0.285714285714286 0.0223463687150838
HP HP:0100360 Contractures of the joints of the upper limbs 0.0114384977375274 270 16 5 0.3125 0.0185185185185185
HP HP:0000973 Cutis laxa 0.0115517252871407 96 84 7 0.0833333333333333 0.0729166666666667
HP HP:0001558 Decreased fetal movement 0.0121015793839388 186 14 4 0.285714285714286 0.021505376344086
HP HP:0011297 Abnormal digit morphology 0.0121745419616979 1284 17 11 0.647058823529412 0.00856697819314642
HP HP:0002795 Abnormal respiratory system physiology 0.0123119224380704 1219 11 8 0.727272727272727 0.00656275635767022
HP HP:0002818 Abnormality of the radius 0.0127903391518194 187 7 3 0.428571428571429 0.0160427807486631
HP HP:0100678 Premature skin wrinkling 0.0127923813766988 50 84 5 0.0595238095238095 0.1
HP HP:0003701 Proximal muscle weakness 0.0132655662503135 192 14 4 0.285714285714286 0.0208333333333333
HP HP:0001627 Abnormal heart morphology 0.0137074967590834 1244 7 6 0.857142857142857 0.00482315112540193
HP HP:0000008 Abnormal morphology of female internal genitalia 0.0138807369339491 437 7 4 0.571428571428571 0.0091533180778032
HP HP:0002751 Kyphoscoliosis 0.0141217486502832 170 50 7 0.14 0.0411764705882353
HP HP:0001557 Prenatal movement abnormality 0.0141344481570605 196 14 4 0.285714285714286 0.0204081632653061
HP HP:0002326 Transient ischemic attack 0.0145542082759414 55 23 3 0.130434782608696 0.0545454545454545
HP HP:0000692 Misalignment of teeth 0.0151368750460406 290 23 6 0.260869565217391 0.0206896551724138
HP HP:0002857 Genu valgum 0.0152662842561197 124 22 4 0.181818181818182 0.032258064516129
HP HP:0011355 Localized skin lesion 0.015439539613683 805 7 5 0.714285714285714 0.0062111801242236
HP HP:0040072 Abnormality of forearm bone 0.0155677837920781 204 7 3 0.428571428571429 0.0147058823529412
HP HP:0002311 Incoordination 0.015613867652562 203 14 4 0.285714285714286 0.0197044334975369
HP HP:0000615 Abnormal pupil morphology 0.0156297503839718 52 52 4 0.0769230769230769 0.0769230769230769
HP HP:0000606 Abnormality of the periorbital region 0.0156297503839718 205 7 3 0.428571428571429 0.0146341463414634
HP HP:0004303 Abnormal muscle fiber morphology 0.015880019775449 205 14 4 0.285714285714286 0.0195121951219512
HP HP:0002973 Abnormality of the forearm 0.0160379312860821 208 7 3 0.428571428571429 0.0144230769230769
HP HP:0002705 High, narrow palate 0.0168751069824062 123 23 4 0.173913043478261 0.032520325203252
HP HP:0010827 Abnormality of the seventh cranial nerve 0.0170206853194981 210 14 4 0.285714285714286 0.019047619047619
HP HP:0010628 Facial palsy 0.0170206853194981 210 14 4 0.285714285714286 0.019047619047619
HP HP:0000975 Hyperhidrosis 0.0170593597912972 129 11 3 0.272727272727273 0.0232558139534884
HP HP:0002205 Recurrent respiratory infections 0.0171233741620275 468 11 5 0.454545454545455 0.0106837606837607
HP HP:0000164 Abnormality of the dentition 0.0173890918479717 836 7 5 0.714285714285714 0.00598086124401914
HP HP:0000812 Abnormal internal genitalia 0.0174816596019145 476 7 4 0.571428571428571 0.00840336134453781
HP HP:3000050 Abnormality of odontoid tissue 0.0181033797387035 176 27 5 0.185185185185185 0.0284090909090909
HP HP:0000939 Osteoporosis 0.018234129356544 257 27 6 0.222222222222222 0.0233463035019455
HP HP:0002878 Respiratory failure 0.0187653437390082 218 14 4 0.285714285714286 0.018348623853211
HP HP:0000218 High palate 0.0190763581933247 631 16 7 0.4375 0.0110935023771791
HP HP:0011354 Generalized abnormality of skin 0.0206310584419984 876 7 5 0.714285714285714 0.00570776255707763
HP HP:0005344 Abnormal carotid artery morphology 0.0207477006514173 65 23 3 0.130434782608696 0.0461538461538462
HP HP:0002597 Abnormality of the vasculature 0.020895585862048 1613 8 7 0.875 0.00433973961562306
HP HP:0002250 Abnormal large intestine morphology 0.0209504128040004 235 7 3 0.428571428571429 0.0127659574468085
HP HP:0011121 Abnormality of skin morphology 0.0221749318661034 1740 11 9 0.818181818181818 0.00517241379310345
HP HP:0010460 Abnormality of the female genitalia 0.0221749318661034 517 7 4 0.571428571428571 0.00773694390715667
HP HP:0002270 Abnormality of the autonomic nervous system 0.0222774733378916 242 7 3 0.428571428571429 0.012396694214876
HP HP:0009121 Abnormal axial skeleton morphology 0.0225766211487565 2298 8 8 1 0.00348128807658834
HP HP:0030319 Weakness of facial musculature 0.0225766211487565 233 14 4 0.285714285714286 0.0171673819742489
HP HP:0100864 Short femoral neck 0.0235347796916077 36 141 5 0.0354609929078014 0.138888888888889
HP HP:0002621 Atherosclerosis 0.0236852168356641 69 23 3 0.130434782608696 0.0434782608695652
HP HP:0002577 Abnormal stomach morphology 0.0241301999453982 250 7 3 0.428571428571429 0.012
HP HP:0000235 Abnormality of the fontanelles or cranial sutures 0.0242527805115165 370 27 7 0.259259259259259 0.0189189189189189
HP HP:0001620 High pitched voice 0.0243393227824605 38 42 3 0.0714285714285714 0.0789473684210526
HP HP:0001626 Abnormality of the cardiovascular system 0.0246019155809244 2327 8 8 1 0.00343790287924366
HP HP:0007024 Pseudobulbar paralysis 0.024960454686895 19 86 3 0.0348837209302326 0.157894736842105
HP HP:0004322 Short stature 0.0250671816467123 1215 4 4 1 0.00329218106995885
HP HP:0003457 EMG abnormality 0.0251203317482124 242 14 4 0.285714285714286 0.0165289256198347
HP HP:0001172 Abnormal thumb morphology 0.0254930137449195 343 16 5 0.3125 0.0145772594752187
HP HP:0003121 Limb joint contracture 0.0263570232221866 346 16 5 0.3125 0.0144508670520231
HP HP:0025142 Constitutional symptom 0.0264619720752705 939 7 5 0.714285714285714 0.0053248136315229
HP HP:0002013 Vomiting 0.0272528369275064 264 7 3 0.428571428571429 0.0113636363636364
HP HP:0001005 Dermatological manifestations of systemic disorders 0.027490490305101 265 7 3 0.428571428571429 0.0113207547169811
HP HP:0002793 Abnormal pattern of respiration 0.0280575563484209 352 16 5 0.3125 0.0142045454545455
HP HP:0001659 Aortic regurgitation 0.0284927142084263 75 23 3 0.130434782608696 0.04
HP HP:0000545 Myopia 0.0298730082227686 346 23 6 0.260869565217391 0.0173410404624277
HP HP:0100261 Abnormal tendon morphology 0.0298730082227686 695 16 7 0.4375 0.0100719424460432
HP HP:0002634 Arteriosclerosis 0.0301809838716605 77 23 3 0.130434782608696 0.038961038961039
HP HP:0012732 Anorectal anomaly 0.0303001233723061 277 7 3 0.428571428571429 0.0108303249097473
HP HP:0001939 Abnormality of metabolism/homeostasis 0.0305482655382424 2203 7 7 1 0.00317748524738992
HP HP:0003236 Elevated serum creatine kinase 0.0312916135415346 261 14 4 0.285714285714286 0.0153256704980843
HP HP:0011947 Respiratory tract infection 0.03142849935158 558 11 5 0.454545454545455 0.00896057347670251
HP HP:0040081 Abnormal circulating creatine kinase concentration 0.0320920836607754 264 14 4 0.285714285714286 0.0151515151515152
HP HP:0011021 Abnormality of circulating enzyme level 0.0327049643340689 266 14 4 0.285714285714286 0.0150375939849624
HP HP:0030680 Abnormality of cardiovascular system morphology 0.0332393618976373 1528 7 6 0.857142857142857 0.00392670157068063
HP HP:0000189 Narrow palate 0.0333859838219254 158 23 4 0.173913043478261 0.0253164556962025
HP HP:0009108 Aplasia/Hypoplasia involving the femoral head and neck 0.0333859838219254 40 141 5 0.0354609929078014 0.125
HP HP:0002460 Distal muscle weakness 0.0336620258080822 177 11 3 0.272727272727273 0.0169491525423729
HP HP:0000951 Abnormality of the skin 0.0341576317639661 1868 11 9 0.818181818181818 0.00481798715203426
HP HP:0001824 Weight loss 0.0349821897570877 273 14 4 0.285714285714286 0.0146520146520147
HP HP:0000768 Pectus carinatum 0.0349821897570877 136 27 4 0.148148148148148 0.0294117647058824
HP HP:0100545 Arterial stenosis 0.037271866214519 85 23 3 0.130434782608696 0.0352941176470588
HP HP:0011368 Epidermal thickening 0.038110195551039 362 17 5 0.294117647058824 0.0138121546961326
HP HP:0007550 Hypohidrosis or hyperhidrosis 0.0399879460970755 190 11 3 0.272727272727273 0.0157894736842105
HP HP:0012531 Pain 0.0407394683565968 636 7 4 0.571428571428571 0.00628930817610063
HP HP:0006824 Cranial nerve paralysis 0.0407842692939532 287 14 4 0.285714285714286 0.0139372822299652
HP HP:0011314 Abnormality of long bone morphology 0.0408705927181685 630 4 3 0.75 0.00476190476190476
HP HP:0031910 Abnormal cranial nerve physiology 0.0411339420601761 288 14 4 0.285714285714286 0.0138888888888889
HP HP:0001999 Abnormal facial shape 0.0413398012226288 1000 5 4 0.8 0.004
HP HP:0003198 Myopathy 0.0416886537337215 290 14 4 0.285714285714286 0.0137931034482759
HP HP:0025276 Abnormality of skin adnexa physiology 0.0426315414231243 196 11 3 0.272727272727273 0.0153061224489796
HP HP:0000539 Abnormality of refraction 0.0427352875757174 531 17 6 0.352941176470588 0.0112994350282486
HP HP:0002020 Gastroesophageal reflux 0.042871046361749 375 17 5 0.294117647058824 0.0133333333333333
HP HP:0005930 Abnormality of epiphysis morphology 0.0431488510950456 239 17 4 0.235294117647059 0.0167364016736402
HP HP:0011029 Internal hemorrhage 0.0433839050447712 282 8 3 0.375 0.0106382978723404
HP HP:0002019 Constipation 0.0447109823765417 332 7 3 0.428571428571429 0.00903614457831325
HP HP:0100749 Chest pain 0.0449533165144097 93 23 3 0.130434782608696 0.032258064516129
HP HP:0000316 Hypertelorism 0.0451524964151726 663 4 3 0.75 0.00452488687782805
HP HP:0009103 Aplasia/Hypoplasia involving the pelvis 0.0453498278667108 61 141 6 0.0425531914893617 0.0983606557377049
HP HP:0001252 Hypotonia 0.0453498278667108 1566 17 11 0.647058823529412 0.0070242656449553
HP HP:0410280 Pediatric onset 0.0456115378061755 627 11 5 0.454545454545455 0.00797448165869218
HP HP:0010876 Abnormal circulating protein concentration 0.0465933682439664 480 14 5 0.357142857142857 0.0104166666666667
HP HP:0002983 Micromelia 0.0468151562559656 100 22 3 0.136363636363636 0.03
HP HP:0000301 Abnormality of facial musculature 0.0472043835442715 306 14 4 0.285714285714286 0.0130718954248366
HP HP:0012758 Neurodevelopmental delay 0.0476674108069723 1976 11 9 0.818181818181818 0.00455465587044534
HP HP:0000492 Abnormal eyelid morphology 0.0481154396404151 1117 7 5 0.714285714285714 0.0044762757385855
KEGG KEGG:04512 ECM-receptor interaction 1.42074766910069e-12 88 44 12 0.272727272727273 0.136363636363636
KEGG KEGG:04974 Protein digestion and absorption 1.42074766910069e-12 103 14 9 0.642857142857143 0.087378640776699
KEGG KEGG:04510 Focal adhesion 1.85074557091715e-08 200 44 12 0.272727272727273 0.06
KEGG KEGG:05146 Amoebiasis 5.93448410435425e-07 101 4 4 1 0.0396039603960396
KEGG KEGG:04933 AGE-RAGE signaling pathway in diabetic complications 5.93448410435425e-07 100 4 4 1 0.04
KEGG KEGG:05165 Human papillomavirus infection 2.72046277094677e-06 331 44 12 0.272727272727273 0.0362537764350453
KEGG KEGG:04151 PI3K-Akt signaling pathway 4.69986072068682e-06 353 44 12 0.272727272727273 0.0339943342776204
KEGG KEGG:04611 Platelet activation 0.000222767808622462 124 4 3 0.75 0.0241935483870968
KEGG KEGG:04926 Relaxin signaling pathway 0.000223054336818557 129 4 3 0.75 0.0232558139534884
KEGG KEGG:05205 Proteoglycans in cancer 0.000733489131109288 205 4 3 0.75 0.0146341463414634
KEGG KEGG:05415 Diabetic cardiomyopathy 0.000733489131109288 203 4 3 0.75 0.0147783251231527
KEGG KEGG:05222 Small cell lung cancer 0.000891596324182177 92 40 5 0.125 0.0543478260869565
KEGG KEGG:04141 Protein processing in endoplasmic reticulum 0.00167094555701282 170 95 9 0.0947368421052632 0.0529411764705882
MIRNA MIRNA:hsa-miR-29b-3p hsa-miR-29b-3p 7.54960958198984e-20 260 56 21 0.375 0.0807692307692308
MIRNA MIRNA:hsa-miR-29c-3p hsa-miR-29c-3p 1.43838309524484e-11 253 56 15 0.267857142857143 0.0592885375494071
MIRNA MIRNA:hsa-miR-29a-3p hsa-miR-29a-3p 7.09135720593972e-09 264 56 13 0.232142857142857 0.0492424242424242
MIRNA MIRNA:hsa-miR-767-5p hsa-miR-767-5p 1.30318183904391e-06 185 60 10 0.166666666666667 0.0540540540540541
MIRNA MIRNA:hsa-miR-218-5p hsa-miR-218-5p 0.000233083790302783 814 142 24 0.169014084507042 0.0294840294840295
MIRNA MIRNA:hsa-miR-133a-3p hsa-miR-133a-3p 0.000233083790302783 129 60 7 0.116666666666667 0.0542635658914729
MIRNA MIRNA:hsa-miR-143-3p hsa-miR-143-3p 0.000428359633448476 227 7 4 0.571428571428571 0.0176211453744493
MIRNA MIRNA:hsa-miR-124-3p hsa-miR-124-3p 0.000673533426239339 1442 84 23 0.273809523809524 0.0159500693481276
MIRNA MIRNA:hsa-miR-29b-1-5p hsa-miR-29b-1-5p 0.00075975076251117 74 7 3 0.428571428571429 0.0405405405405405
MIRNA MIRNA:hsa-miR-4677-3p hsa-miR-4677-3p 0.0248467769648595 74 54 4 0.0740740740740741 0.0540540540540541
MIRNA MIRNA:hsa-miR-200c-3p hsa-miR-200c-3p 0.0250911647223404 214 81 7 0.0864197530864197 0.0327102803738318
MIRNA MIRNA:hsa-miR-5689 hsa-miR-5689 0.0329196995507866 57 79 4 0.0506329113924051 0.0701754385964912
MIRNA MIRNA:hsa-miR-200b-3p hsa-miR-200b-3p 0.0361288268254673 185 26 4 0.153846153846154 0.0216216216216216
MIRNA MIRNA:hsa-miR-4679 hsa-miR-4679 0.0448138667570182 68 76 4 0.0526315789473684 0.0588235294117647
MIRNA MIRNA:hsa-miR-3605-5p hsa-miR-3605-5p 0.0448138667570182 107 48 4 0.0833333333333333 0.0373831775700935
REAC REAC:R-HSA-1474244 Extracellular matrix organization 1.47855622221149e-35 298 80 38 0.475 0.12751677852349
REAC REAC:R-HSA-1474290 Collagen formation 4.55034365321172e-29 89 128 27 0.2109375 0.303370786516854
REAC REAC:R-HSA-1650814 Collagen biosynthesis and modifying enzymes 2.08453910040829e-24 67 128 22 0.171875 0.328358208955224
REAC REAC:R-HSA-3000178 ECM proteoglycans 2.15297673827904e-24 75 44 17 0.386363636363636 0.226666666666667
REAC REAC:R-HSA-2022090 Assembly of collagen fibrils and other multimeric structures 6.10427986927896e-20 60 24 12 0.5 0.2
REAC REAC:R-HSA-216083 Integrin cell surface interactions 9.41443476176392e-20 84 44 15 0.340909090909091 0.178571428571429
REAC REAC:R-HSA-1474228 Degradation of the extracellular matrix 3.20157952738113e-19 140 38 16 0.421052631578947 0.114285714285714
REAC REAC:R-HSA-3000170 Syndecan interactions 5.28249439642706e-19 26 44 11 0.25 0.423076923076923
REAC REAC:R-HSA-3000171 Non-integrin membrane-ECM interactions 1.6851786563677e-18 58 44 13 0.295454545454545 0.224137931034483
REAC REAC:R-HSA-8948216 Collagen chain trimerization 1.05019630130356e-17 44 14 9 0.642857142857143 0.204545454545455
REAC REAC:R-HSA-8874081 MET activates PTK2 signaling 8.77162670519007e-17 30 38 10 0.263157894736842 0.333333333333333
REAC REAC:R-HSA-1442490 Collagen degradation 3.3708065851101e-16 64 14 9 0.642857142857143 0.140625
REAC REAC:R-HSA-8875878 MET promotes cell motility 2.0438721211629e-15 40 38 10 0.263157894736842 0.25
REAC REAC:R-HSA-8957275 Post-translational protein phosphorylation 3.88732548424122e-13 107 34 11 0.323529411764706 0.102803738317757
REAC REAC:R-HSA-6806834 Signaling by MET 1.79380621646019e-12 76 38 10 0.263157894736842 0.131578947368421
REAC REAC:R-HSA-381426 Regulation of Insulin-like Growth Factor (IGF) transport and uptake by Insulin-like Growth Factor Binding Proteins (IGFBPs) 1.79380621646019e-12 124 34 11 0.323529411764706 0.0887096774193548
REAC REAC:R-HSA-9006934 Signaling by Receptor Tyrosine Kinases 7.997798149409e-12 485 11 10 0.909090909090909 0.0206185567010309
REAC REAC:R-HSA-419037 NCAM1 interactions 2.31267555588819e-11 42 11 6 0.545454545454545 0.142857142857143
REAC REAC:R-HSA-1566948 Elastic fibre formation 4.1583511505681e-11 44 61 9 0.147540983606557 0.204545454545455
REAC REAC:R-HSA-186797 Signaling by PDGF 1.01975698581085e-10 54 11 6 0.545454545454545 0.111111111111111
REAC REAC:R-HSA-375165 NCAM signaling for neurite out-growth 1.69087228777506e-10 59 11 6 0.545454545454545 0.101694915254237
REAC REAC:R-HSA-2243919 Crosslinking of collagen fibrils 2.86259716396446e-09 18 52 6 0.115384615384615 0.333333333333333
REAC REAC:R-HSA-3000480 Scavenging by Class A Receptors 2.8620782288952e-07 19 4 3 0.75 0.157894736842105
REAC REAC:R-HSA-2129379 Molecules associated with elastic fibres 8.15844102046316e-07 37 61 6 0.0983606557377049 0.162162162162162
REAC REAC:R-HSA-3000157 Laminin interactions 1.07137573332828e-06 30 40 5 0.125 0.166666666666667
REAC REAC:R-HSA-76009 Platelet Aggregation (Plug Formation) 2.20120531048159e-06 38 4 3 0.75 0.0789473684210526
REAC REAC:R-HSA-162582 Signal Transduction 3.84089581679167e-06 2705 11 11 1 0.00406654343807763
REAC REAC:R-HSA-2173782 Binding and Uptake of Ligands by Scavenger Receptors 4.9952015148856e-06 95 8 4 0.5 0.0421052631578947
REAC REAC:R-HSA-2214320 Anchoring fibril formation 5.30336825946522e-05 15 24 3 0.125 0.2
REAC REAC:R-HSA-76002 Platelet activation, signaling and aggregation 6.35241057785096e-05 258 20 6 0.3 0.0232558139534884
REAC REAC:R-HSA-422475 Axon guidance 7.43140274639166e-05 549 11 6 0.545454545454545 0.0109289617486339
REAC REAC:R-HSA-75892 Platelet Adhesion to exposed collagen 7.51769342832258e-05 15 28 3 0.107142857142857 0.2
REAC REAC:R-HSA-9675108 Nervous system development 9.05092396690029e-05 574 11 6 0.545454545454545 0.0104529616724739
REAC REAC:R-HSA-198933 Immunoregulatory interactions between a Lymphoid and a non-Lymphoid cell 0.000186478680534881 181 4 3 0.75 0.0165745856353591
REAC REAC:R-HSA-202733 Cell surface interactions at the vascular wall 0.000209740396875587 190 4 3 0.75 0.0157894736842105
REAC REAC:R-HSA-114608 Platelet degranulation 0.000688125186868359 125 20 4 0.2 0.032
REAC REAC:R-HSA-76005 Response to elevated platelet cytosolic Ca2+ 0.000781067972983679 130 20 4 0.2 0.0307692307692308
REAC REAC:R-HSA-6785807 Interleukin-4 and Interleukin-13 signaling 0.00153336589115879 110 28 4 0.142857142857143 0.0363636363636364
REAC REAC:R-HSA-446203 Asparagine N-linked glycosylation 0.00180564442250844 304 142 13 0.0915492957746479 0.0427631578947368
REAC REAC:R-HSA-1266738 Developmental Biology 0.00243954915011361 1069 11 6 0.545454545454545 0.00561272217025257
REAC REAC:R-HSA-597592 Post-translational protein modification 0.0035680989123798 1377 46 15 0.326086956521739 0.0108932461873638
REAC REAC:R-HSA-1592389 Activation of Matrix Metalloproteinases 0.0055716215590865 33 135 4 0.0296296296296296 0.121212121212121
REAC REAC:R-HSA-109582 Hemostasis 0.00591077083951417 657 8 4 0.5 0.0060882800608828
REAC REAC:R-HSA-983170 Antigen Presentation: Folding, assembly and peptide loading of class I MHC 0.00602688960944886 25 81 3 0.037037037037037 0.12
REAC REAC:R-HSA-5653656 Vesicle-mediated transport 0.00789863483827318 717 4 3 0.75 0.00418410041841004
REAC REAC:R-HSA-1280218 Adaptive Immune System 0.0106940594319995 800 4 3 0.75 0.00375
REAC REAC:R-HSA-168256 Immune System 0.0107931783471422 2139 4 4 1 0.0018700327255727
REAC REAC:R-HSA-199977 ER to Golgi Anterograde Transport 0.0165050182100651 154 131 7 0.0534351145038168 0.0454545454545455
REAC REAC:R-HSA-3781865 Diseases of glycosylation 0.0165050182100651 140 107 6 0.0560747663551402 0.0428571428571429
REAC REAC:R-HSA-948021 Transport to the Golgi and subsequent modification 0.0165050182100651 185 139 8 0.0575539568345324 0.0432432432432432
REAC REAC:R-HSA-3906995 Diseases associated with O-glycosylation of proteins 0.0222544978820532 65 107 4 0.0373831775700935 0.0615384615384615
REAC REAC:R-HSA-1236975 Antigen processing-Cross presentation 0.0227935955122318 99 71 4 0.0563380281690141 0.0404040404040404
REAC REAC:R-HSA-204005 COPII-mediated vesicle transport 0.0244110890596467 67 108 4 0.037037037037037 0.0597014925373134
REAC REAC:R-HSA-5083635 Defective B3GALTL causes Peters-plus syndrome (PpS) 0.0256515013270313 35 107 3 0.0280373831775701 0.0857142857142857
REAC REAC:R-HSA-5173214 O-glycosylation of TSR domain-containing proteins 0.0273766648538472 36 107 3 0.0280373831775701 0.0833333333333333
REAC REAC:R-HSA-449147 Signaling by Interleukins 0.0275699361207275 446 28 5 0.178571428571429 0.0112107623318386
REAC REAC:R-HSA-373760 L1CAM interactions 0.0353228060904518 119 70 4 0.0571428571428571 0.0336134453781513
REAC REAC:R-HSA-174824 Plasma lipoprotein assembly, remodeling, and clearance 0.0411477852804407 67 70 3 0.0428571428571429 0.0447761194029851
TF TF:M01858_1 Factor: AP-2beta; motif: GCNNNGGSCNGVGGGN; match class: 1 4.14077521627864e-06 3141 116 46 0.396551724137931 0.014645017510347
TF TF:M10108 Factor: WT1; motif: RGGNGGGGGAGGRGGNGGRG 4.67373764866159e-05 6511 141 79 0.560283687943262 0.0121333128551682
TF TF:M10134 Factor: FPM315; motif: GGGAGGAGGRRGRGGRGGRR 9.10270737718505e-05 2472 141 42 0.297872340425532 0.0169902912621359
TF TF:M01175_1 Factor: CKROX; motif: SCCCTCCCC; match class: 1 0.000279909051846158 2679 43 20 0.465116279069767 0.00746547219111609
TF TF:M00695_1 Factor: ETF; motif: GVGGMGG; match class: 1 0.000313611857544368 7032 141 80 0.567375886524823 0.0113765642775882
TF TF:M10107 Factor: DB1; motif: GGRRRRGRRGGAGGGGGNGRRR 0.000400023039120418 5822 141 70 0.49645390070922 0.0120233596702164
TF TF:M06948 Factor: Sp2; motif: TGGGCGCGCCCA 0.000407508714170334 8864 136 90 0.661764705882353 0.0101534296028881
TF TF:M00915 Factor: AP-2; motif: SNNNCCNCAGGCN 0.000407508714170334 9612 143 99 0.692307692307692 0.0102996254681648
TF TF:M02089_1 Factor: E2F-3; motif: GGCGGGN; match class: 1 0.000453120441757192 9362 143 97 0.678321678321678 0.010361033967101
TF TF:M01858 Factor: AP-2beta; motif: GCNNNGGSCNGVGGGN 0.000478271172016532 7418 125 74 0.592 0.00997573469937989
TF TF:M11235_1 Factor: OASIS; motif: YGCCACGTCANC; match class: 1 0.00101430898095781 14 131 4 0.0305343511450382 0.285714285714286
TF TF:M07039_1 Factor: ETF; motif: CCCCGCCCCYN; match class: 1 0.00101430898095781 13611 143 123 0.86013986013986 0.00903680846374256
TF TF:M10107_1 Factor: DB1; motif: GGRRRRGRRGGAGGGGGNGRRR; match class: 1 0.00113254395380375 2657 141 40 0.283687943262411 0.015054572826496
TF TF:M11256 Factor: AIBZIP; motif: NGCCACGTCAYN 0.00113254395380375 1323 142 26 0.183098591549296 0.0196523053665911
TF TF:M10026 Factor: PATZ; motif: GGGGNGGGGGMKGGRRNGGNRN 0.00140582635485111 8389 141 87 0.617021276595745 0.0103707235665753
TF TF:M00196 Factor: Sp1; motif: NGGGGGCGGGGYN 0.0014182769409399 10233 143 101 0.706293706293706 0.00987002833968533
TF TF:M10071 Factor: Sp1; motif: NGGGGGCGGGGCCNGGGGGGGG 0.00149170722752217 8495 68 48 0.705882352941177 0.00565038257798705
TF TF:M08205_1 Factor: E2F-1:Elk-1; motif: SGCGCSNNAMCGGAAGT; match class: 1 0.00158621747076764 10438 77 60 0.779220779220779 0.00574822762981414
TF TF:M07395 Factor: Sp1; motif: NGGGGCGGGGN 0.00158621747076764 10640 82 64 0.780487804878049 0.00601503759398496
TF TF:M00470_1 Factor: AP-2gamma; motif: GCCYNNGGS; match class: 1 0.00158621747076764 5600 127 60 0.47244094488189 0.0107142857142857
TF TF:M01770_1 Factor: XBP-1; motif: WNNGMCACGTC; match class: 1 0.00177383827435132 4554 90 40 0.444444444444444 0.00878348704435661
TF TF:M09723 Factor: BTEB1; motif: GGGGGCGGGGCNGSGGGNGS 0.00177383827435132 10156 68 53 0.779411764705882 0.00521858999606144
TF TF:M09636_1 Factor: MAZ; motif: GGGMGGGGSSGGGGGGGGGGGG; match class: 1 0.00198465336288435 14096 135 118 0.874074074074074 0.00837116912599319
TF TF:M11235 Factor: OASIS; motif: YGCCACGTCANC 0.00198465336288435 368 134 12 0.0895522388059701 0.0326086956521739
TF TF:M10112_1 Factor: Miz-1; motif: NNRGGWGGGGGAGGGGMRR; match class: 1 0.00198465336288435 4075 64 29 0.453125 0.00711656441717791
TF TF:M07141 Factor: FPM315; motif: GGAGGAGGRRGRGGRGGRRGR 0.00198465336288435 2175 141 34 0.24113475177305 0.015632183908046
TF TF:M10134_1 Factor: FPM315; motif: GGGAGGAGGRRGRGGRGGRR; match class: 1 0.00211058341583646 585 11 5 0.454545454545455 0.00854700854700855
TF TF:M10008_1 Factor: CSX; motif: NKRAGWGS; match class: 1 0.00230798561298528 3963 143 51 0.356643356643357 0.0128690386071158
TF TF:M10108_1 Factor: WT1; motif: RGGNGGGGGAGGRGGNGGRG; match class: 1 0.00258676330605335 2864 47 19 0.404255319148936 0.0066340782122905
TF TF:M00915_1 Factor: AP-2; motif: SNNNCCNCAGGCN; match class: 1 0.00258676330605335 4551 108 45 0.416666666666667 0.00988793671720501
TF TF:M00333_1 Factor: ZF5; motif: NRNGNGCGCGCWN; match class: 1 0.00258676330605335 12401 135 108 0.8 0.00870897508265463
TF TF:M09968 Factor: KLF15; motif: RGGGMGGRGNNGGGGGNGG 0.00258676330605335 3157 128 40 0.3125 0.0126702565726956
TF TF:M06948_1 Factor: Sp2; motif: TGGGCGCGCCCA; match class: 1 0.00321150613375406 6205 74 41 0.554054054054054 0.00660757453666398
TF TF:M09984 Factor: MAZ; motif: GGGGGAGGGGGNGRGRRRGNRG 0.00340065914119869 9544 141 93 0.659574468085106 0.00974434199497066
TF TF:M03806 Factor: ZBTB7C; motif: GKCCCGGGCKG 0.00358069228065634 3031 126 38 0.301587301587302 0.0125371164632135
TF TF:M09739 Factor: ZGPAT; motif: GRGGCWGNGGNG 0.00381417565555182 8226 80 52 0.65 0.00632141988815949
TF TF:M11247 Factor: Luman; motif: YGCCACGTCAYC 0.00433796033697954 174 134 8 0.0597014925373134 0.0459770114942529
TF TF:M04106_1 Factor: RUNX2; motif: NRACCGCAAACCGCAN; match class: 1 0.00454428995152342 8372 131 79 0.603053435114504 0.00943621595795509
TF TF:M07289_1 Factor: GKLF; motif: NNNRGGNGNGGSN; match class: 1 0.00454428995152342 10555 134 95 0.708955223880597 0.00900047370914259
TF TF:M04516_1 Factor: E2F-1; motif: TTTGGCGCCAAA; match class: 1 0.00471370112989824 10227 131 91 0.694656488549618 0.00889801505817933
TF TF:M11401 Factor: Fli-1; motif: NACCGGATATCCGGTN 0.00480991319064821 11952 75 62 0.826666666666667 0.00518741633199465
TF TF:M08911 Factor: CTCF; motif: NCCRSTAGGGGGCGC 0.00480991319064821 9094 139 88 0.633093525179856 0.00967670991862767
TF TF:M04863_1 Factor: TF3C-beta; motif: CCNGGAGGGCTTCCTGGAGGAG; match class: 1 0.00492105878314935 8573 62 43 0.693548387096774 0.00501574711302928
TF TF:M08905 Factor: TIEG1; motif: GGSGGKGNNN 0.00493762397135671 5153 100 45 0.45 0.00873277702309334
TF TF:M02089 Factor: E2F-3; motif: GGCGGGN 0.00528421046588884 13173 82 71 0.865853658536585 0.00538981249525545
TF TF:M11603_1 Factor: TCF-1; motif: ACATCGRGRCGCTGW; match class: 1 0.00537126352866683 13184 82 71 0.865853658536585 0.00538531553398058
TF TF:M01873 Factor: Egr-1; motif: GCGGGGGCGG 0.00537126352866683 6738 133 68 0.511278195488722 0.0100920154348471
TF TF:M00695 Factor: ETF; motif: GVGGMGG 0.00537126352866683 10430 141 98 0.695035460992908 0.00939597315436242
TF TF:M01104_1 Factor: MOVO-B; motif: GNGGGGG; match class: 1 0.00597990843439742 5626 126 57 0.452380952380952 0.0101315321720583
TF TF:M00649_1 Factor: MAZ; motif: GGGGAGGG; match class: 1 0.00618171695753951 4166 43 21 0.488372093023256 0.00504080652904465
TF TF:M00932 Factor: Sp1; motif: NNGGGGCGGGGNN 0.00618171695753951 10419 82 61 0.74390243902439 0.00585468854976485
TF TF:M07261 Factor: LKLF; motif: GGGGTGGKSN 0.00713609368991174 9774 141 93 0.659574468085106 0.00951503990178023
TF TF:M10116 Factor: ZID; motif: GGNGMTGGAGCCN 0.00789507887249198 1601 67 16 0.238805970149254 0.00999375390381012
TF TF:M11227 Factor: ATF-6; motif: TGRTGACGTGGCAN 0.00789507887249198 201 134 8 0.0597014925373134 0.0398009950248756
TF TF:M00931 Factor: Sp1; motif: GGGGCGGGGC 0.00789507887249198 10281 134 92 0.686567164179104 0.00894854586129754
TF TF:M00333 Factor: ZF5; motif: NRNGNGCGCGCWN 0.00789507887249198 15072 135 121 0.896296296296296 0.00802813163481953
TF TF:M00986_1 Factor: Churchill; motif: CGGGNN; match class: 1 0.00789507887249198 10357 143 98 0.685314685314685 0.0094621994786135
TF TF:M09826 Factor: BTEB3; motif: CCNNSCCNSCCCCKCCCCC 0.00848344524293718 11467 77 61 0.792207792207792 0.00531961280195343
TF TF:M08214_1 Factor: Elk-1:ETV7; motif: ANSCGGACGGATDTCCGGNT; match class: 1 0.00864221749899144 2312 26 11 0.423076923076923 0.00475778546712803
TF TF:M08905_1 Factor: TIEG1; motif: GGSGGKGNNN; match class: 1 0.00865356155443538 1017 126 18 0.142857142857143 0.0176991150442478
TF TF:M11274_1 Factor: XBP-1; motif: NGMCACRTCAYC; match class: 1 0.00920387682454086 109 131 6 0.0458015267175573 0.055045871559633
TF TF:M05432 Factor: ZSCAN18; motif: TRRCGRCGNMCC 0.00929316893455182 4117 141 49 0.347517730496454 0.0119018702939033
TF TF:M00469 Factor: AP-2alpha; motif: GCCNNNRGS 0.00982846433296464 5147 98 43 0.438775510204082 0.00835438119292792
TF TF:M11529_1 Factor: E2F-2; motif: GCGCGCGCNCS; match class: 1 0.00982846433296464 14473 77 70 0.909090909090909 0.00483659227527119
TF TF:M09970 Factor: KLF3; motif: NNNNNNGGGCGGGGCNNGN 0.00982846433296464 7728 134 74 0.552238805970149 0.00957556935817805
TF TF:M00803_1 Factor: E2F; motif: GGCGSG; match class: 1 0.00982846433296464 10230 134 91 0.67910447761194 0.00889540566959922
TF TF:M09894_1 Factor: E2F-4; motif: SNGGGCGGGAANN; match class: 1 0.00982846433296464 13929 64 58 0.90625 0.00416397444181205
TF TF:M03971 Factor: ELK1; motif: NACTTCCGSCGGAAGYN 0.00982846433296464 11293 74 58 0.783783783783784 0.00513592490923581
TF TF:M07615 Factor: Sp3; motif: GGGGCGGGGSNN 0.00982846433296464 6807 123 63 0.51219512195122 0.00925517849272807
TF TF:M01100 Factor: LRF; motif: GGGGKYNNB 0.00982846433296464 7557 134 73 0.544776119402985 0.00965991795686119
TF TF:M11256_1 Factor: AIBZIP; motif: NGCCACGTCAYN; match class: 1 0.00982846433296464 75 66 4 0.0606060606060606 0.0533333333333333
TF TF:M09734_1 Factor: ZNF692; motif: SYNGGSCCCASCCNC; match class: 1 0.00982846433296464 6255 50 29 0.58 0.00463629096722622
TF TF:M10020_1 Factor: OSR2; motif: NNNNCWGCTNCTGNNG; match class: 1 0.00982846433296464 667 83 11 0.132530120481928 0.0164917541229385
TF TF:M07297 Factor: MAZ; motif: CCCTCCCYCYN 0.00982846433296464 2964 143 39 0.272727272727273 0.0131578947368421
TF TF:M08867 Factor: AP2; motif: GCCYGSGGSN 0.00982846433296464 10054 141 94 0.666666666666667 0.00934951263178834
TF TF:M09984_1 Factor: MAZ; motif: GGGGGAGGGGGNGRGRRRGNRG; match class: 1 0.00982846433296464 5555 128 56 0.4375 0.0100810081008101
TF TF:M01112 Factor: RBP-Jkappa; motif: ANCGTGGGAAM 0.0105118847852946 2796 142 37 0.26056338028169 0.0132331902718169
TF TF:M10438_1 Factor: ZF5; motif: GGSGCGCGS; match class: 1 0.0105118847852946 14873 77 71 0.922077922077922 0.00477375109258388
TF TF:M10432 Factor: MAZ; motif: GGGMGGGGS 0.0105118847852946 9259 126 80 0.634920634920635 0.00864024192677395
TF TF:M10026_1 Factor: PATZ; motif: GGGGNGGGGGMKGGRRNGGNRN; match class: 1 0.0105118847852946 4894 141 55 0.390070921985816 0.0112382509194933
TF TF:M07375 Factor: BCL-6; motif: TTCCTAGAAA 0.0105118847852946 556 29 6 0.206896551724138 0.0107913669064748
TF TF:M12351 Factor: TIEG1; motif: NCCCNSNCCCCGCCCCC 0.0107675204489471 12302 143 110 0.769230769230769 0.00894163550642172
TF TF:M10072 Factor: sp4; motif: NNGNARGRGGCGGRGCNNRR 0.0107675204489471 10494 77 57 0.74025974025974 0.005431675242996
TF TF:M08525_1 Factor: E2F-1:HES-7; motif: GGCRCGTGSYNNWNGGCGCSM; match class: 1 0.0108969088022049 15268 77 72 0.935064935064935 0.00471574534975111
TF TF:M12354 Factor: ZNF37A; motif: CCYYGGCTCCNTSCCMN 0.0112117672142667 10961 143 101 0.706293706293706 0.00921448772922179
TF TF:M11401_1 Factor: Fli-1; motif: NACCGGATATCCGGTN; match class: 1 0.0115976814916455 11801 85 67 0.788235294117647 0.00567748495890179
TF TF:M12354_1 Factor: ZNF37A; motif: CCYYGGCTCCNTSCCMN; match class: 1 0.0115976814916455 5624 142 61 0.429577464788732 0.010846372688478
TF TF:M00931_1 Factor: Sp1; motif: GGGGCGGGGC; match class: 1 0.0118668293055269 5905 128 58 0.453125 0.00982218458933107
TF TF:M07354 Factor: Egr-1; motif: GCGGGGGCGG 0.0118722149573991 7801 134 74 0.552238805970149 0.00948596333803359
TF TF:M00196_1 Factor: Sp1; motif: NGGGGGCGGGGYN; match class: 1 0.0119439419500901 5919 68 35 0.514705882352941 0.00591316100692685
TF TF:M11253 Factor: AIBZIP; motif: YGCCACGTCACC 0.0119639233742961 229 134 8 0.0597014925373134 0.0349344978165939
TF TF:M09826_1 Factor: BTEB3; motif: CCNNSCCNSCCCCKCCCCC; match class: 1 0.0119639233742961 7508 48 31 0.645833333333333 0.00412892914224827
TF TF:M12160 Factor: KLF15; motif: RCCMCRCCCMCN 0.0119639233742961 12729 134 106 0.791044776119403 0.00832744127582685
TF TF:M01835_1 Factor: GKLF; motif: CCTCCYN; match class: 1 0.0128185066365092 10142 143 95 0.664335664335664 0.00936698875961349
TF TF:M09760_1 Factor: DPF2; motif: NYCACYTCCYCNYYCY; match class: 1 0.0128235328371546 2978 141 38 0.269503546099291 0.012760241773002
TF TF:M10533 Factor: ZID; motif: NGGNGCTGGAGCCNS 0.0129076797757027 1749 67 16 0.238805970149254 0.00914808461978273
TF TF:M01721 Factor: PUR1; motif: GGGNCAGNN 0.0130161965359565 9145 134 83 0.619402985074627 0.00907599781301257
TF TF:M01721_1 Factor: PUR1; motif: GGGNCAGNN; match class: 1 0.0135745552584221 3414 129 39 0.302325581395349 0.0114235500878735
TF TF:M11478_1 Factor: AP-2beta; motif: NSCCNNNGGSN; match class: 1 0.0135745552584221 8037 121 69 0.570247933884298 0.0085852930197835
TF TF:M02036 Factor: WT1; motif: CGCCCCCNCN 0.0139373579482864 9767 141 91 0.645390070921986 0.00931708815398792
TF TF:M07063 Factor: Sp1; motif: GGGGCGGGGC 0.0140999951836273 7696 128 70 0.546875 0.0090956340956341
TF TF:M10435 Factor: Sp2; motif: GGGGCGGGG 0.0140999951836273 7696 128 70 0.546875 0.0090956340956341
TF TF:M02090_1 Factor: E2F-4; motif: GCGGGAAANA; match class: 1 0.0143103514131615 6378 31 20 0.645161290322581 0.00313577924114142
TF TF:M07348 Factor: AP-2alpha; motif: NSCCNCRGGSN 0.0146596996112835 8047 142 79 0.556338028169014 0.00981732322604697
TF TF:M11022 Factor: IRX2a; motif: ACRYGNNNNACRYGT 0.0146864461250547 9487 95 63 0.663157894736842 0.00664066617476547
TF TF:M07261_1 Factor: LKLF; motif: GGGGTGGKSN; match class: 1 0.0146864461250547 4062 133 45 0.338345864661654 0.0110782865583456
TF TF:M03976_1 Factor: ERG; motif: ACCGGAWATCCGGT; match class: 1 0.0146864461250547 7781 59 37 0.627118644067797 0.00475517285695926
TF TF:M10020 Factor: OSR2; motif: NNNNCWGCTNCTGNNG 0.0150839971885393 2584 141 34 0.24113475177305 0.0131578947368421
TF TF:M12158 Factor: KLF15; motif: NCCMCGCCCMCN 0.015322305940538 11088 143 101 0.706293706293706 0.00910894660894661
TF TF:M00706_1 Factor: TFII-I; motif: RGAGGKAGG; match class: 1 0.0154632650539878 1590 130 23 0.176923076923077 0.0144654088050314
TF TF:M00470 Factor: AP-2gamma; motif: GCCYNNGGS 0.016583010801127 9422 130 82 0.630769230769231 0.00870303544894927
TF TF:M04953 Factor: Sp1; motif: GGNDGGRGGCGGGG 0.016583010801127 8688 58 39 0.672413793103448 0.00448895027624309
TF TF:M01303 Factor: SP1; motif: GGGGYGGGGNS 0.016583010801127 7898 143 78 0.545454545454545 0.00987591795391238
TF TF:M00716_1 Factor: ZF5; motif: GSGCGCGR; match class: 1 0.0170827356609754 14106 135 114 0.844444444444444 0.00808166737558486
TF TF:M09973_1 Factor: CPBP; motif: GNNRGGGHGGGGNNGGGRN; match class: 1 0.0175252260450053 6607 143 68 0.475524475524476 0.0102921144240957
TF TF:M04811 Factor: RelA-p65; motif: BCWGGGRANNK 0.0175252260450053 7311 142 73 0.514084507042254 0.00998495417863493
TF TF:M01131_1 Factor: Sox-10; motif: CWTTGTN; match class: 1 0.0178805143100843 2650 9 6 0.666666666666667 0.00226415094339623
TF TF:M11531_1 Factor: E2F-2; motif: GCGCGCGCGYW; match class: 1 0.0182356198335935 12351 75 61 0.813333333333333 0.00493887134644968
TF TF:M07039 Factor: ETF; motif: CCCCGCCCCYN 0.0182356198335935 16384 135 126 0.933333333333333 0.0076904296875
TF TF:M09910 Factor: ER-beta; motif: RGGTCASCNTGMCCY 0.0182356198335935 9520 61 43 0.704918032786885 0.00451680672268908
TF TF:M00469_1 Factor: AP-2alpha; motif: GCCNNNRGS; match class: 1 0.0182356198335935 3334 126 37 0.293650793650794 0.0110977804439112
TF TF:M00736_1 Factor: E2F-1:DP-1; motif: TTTCSCGC; match class: 1 0.0182356198335935 4639 41 20 0.48780487804878 0.00431127398146152
TF TF:M01587 Factor: FPM315; motif: SRGGGAGGAGGN 0.0182356198335935 3246 85 27 0.317647058823529 0.00831792975970425
TF TF:M01857_1 Factor: AP-2alpha; motif: NGCCYSNNGSN; match class: 1 0.0187709195166295 4616 81 33 0.407407407407407 0.00714904679376083
TF TF:M11255_1 Factor: AIBZIP; motif: YGCCACGTGGCN; match class: 1 0.0187709195166295 409 85 8 0.0941176470588235 0.019559902200489
TF TF:M08878 Factor: EGR; motif: CGCCCCCGCNN 0.0188591758490226 7483 133 70 0.526315789473684 0.00935453695042095
TF TF:M07329 Factor: Osx; motif: CCNCCCCCNNN 0.0191554265512414 6803 67 37 0.552238805970149 0.00543877701014258
TF TF:M09658 Factor: Sp2; motif: GGSNNGGGGGCGGGGCCNGNGS 0.0194903785866349 5262 64 30 0.46875 0.00570125427594071
TF TF:M10086 Factor: TAFII250; motif: RARRWGGCGGMGGNGR 0.0194903785866349 9262 142 87 0.612676056338028 0.00939321960699633
TF TF:M09738_1 Factor: ZNF511; motif: GGRRGRGGCWGNG; match class: 1 0.0194903785866349 4738 35 18 0.514285714285714 0.00379907133811735
TF TF:M05821 Factor: ZNF880; motif: GGAGGGCTYK 0.020631504949706 203 132 7 0.053030303030303 0.0344827586206897
TF TF:M10477 Factor: ZNF436; motif: TCCTCCAGGAAGCCY 0.0213569266445229 14518 77 69 0.896103896103896 0.00475272076043532
TF TF:M10438 Factor: ZF5; motif: GGSGCGCGS 0.0215064682148303 16228 143 132 0.923076923076923 0.00813408922849396
TF TF:M08208_1 Factor: E2F-3:FOXI1; motif: NGACACCGCGCCCAC; match class: 1 0.0215064682148303 7127 67 38 0.567164179104478 0.00533183667742388
TF TF:M12351_1 Factor: TIEG1; motif: NCCCNSNCCCCGCCCCC; match class: 1 0.0215404694297723 8180 56 36 0.642857142857143 0.00440097799511002
TF TF:M10530 Factor: sp4; motif: NNNGCYCCGCCCCCY 0.0216938215127386 8227 77 47 0.61038961038961 0.00571289656010696
TF TF:M11393_1 Factor: Erg; motif: NACCGGATATCCGGTN; match class: 1 0.0223457436491788 13665 74 64 0.864864864864865 0.00468349798755946
TF TF:M09636 Factor: MAZ; motif: GGGMGGGGSSGGGGGGGGGGGG 0.0223485234595255 16244 135 125 0.925925925925926 0.00769514897808422
TF TF:M08888_1 Factor: MAFB; motif: NTCAGCN; match class: 1 0.0226332540546608 3375 8 6 0.75 0.00177777777777778
TF TF:M08214 Factor: Elk-1:ETV7; motif: ANSCGGACGGATDTCCGGNT 0.0235869719510014 7951 31 22 0.709677419354839 0.00276694755376682
TF TF:M00444 Factor: VDR; motif: GGGKNARNRRGGWSA 0.0235869719510014 10308 66 48 0.727272727272727 0.00465657741559953
TF TF:M03978_1 Factor: ETS1; motif: GCCGGAWGTACTTCCGGN; match class: 1 0.023921041685785 6486 32 20 0.625 0.00308356460067838
TF TF:M11229 Factor: ATF-6; motif: TGRTGACGTGGCAN 0.023921041685785 342 134 9 0.0671641791044776 0.0263157894736842
TF TF:M06527 Factor: ZNF675; motif: TGAAAGGGGA 0.0244756159155758 171 118 6 0.0508474576271186 0.0350877192982456
TF TF:M04516 Factor: E2F-1; motif: TTTGGCGCCAAA 0.025449775000396 11383 131 94 0.717557251908397 0.00825792848985329
TF TF:M11529 Factor: E2F-2; motif: GCGCGCGCNCS 0.0256952979226861 16263 82 78 0.951219512195122 0.00479616306954436
TF TF:M12227 Factor: ZIC4; motif: NNCCNCCCRYNGYGN 0.0257511117693253 11063 81 60 0.740740740740741 0.00542348368435325
TF TF:M08867_1 Factor: AP2; motif: GCCYGSGGSN; match class: 1 0.0259498476196564 5186 141 55 0.390070921985816 0.0106054762822985
TF TF:M00932_1 Factor: Sp1; motif: NNGGGGCGGGGNN; match class: 1 0.0259498476196564 6047 128 57 0.4453125 0.00942616173309079
TF TF:M10085 Factor: RBPJK; motif: NSNSTGGGAAN 0.0260758328030431 3436 63 22 0.349206349206349 0.00640279394644936
TF TF:M07395_1 Factor: Sp1; motif: NGGGGCGGGGN; match class: 1 0.0261149811835736 6334 128 59 0.4609375 0.00931480896747711
TF TF:M11478 Factor: AP-2beta; motif: NSCCNNNGGSN 0.0263029953194874 9942 121 79 0.652892561983471 0.00794608730637699
TF TF:M09628 Factor: HTF4; motif: NNSCAGGTGNN 0.0269408311263903 382 76 7 0.0921052631578947 0.0183246073298429
TF TF:M11393 Factor: Erg; motif: NACCGGATATCCGGTN 0.0271781553861807 14105 74 65 0.878378378378378 0.00460829493087558
TF TF:M11246 Factor: OASIS; motif: YGCCACGTRNNCN 0.0277861286337058 207 140 7 0.05 0.0338164251207729
TF TF:M07208 Factor: EGR1; motif: NCNCCGCCCCCGCN 0.028281017264754 6183 82 40 0.48780487804878 0.00646935144751739
TF TF:M10151 Factor: EZI; motif: GGGGAGGGGRRGGRGRRGGRRR 0.0289395344191103 2108 35 11 0.314285714285714 0.00521821631878558
TF TF:M04149_1 Factor: TFAP2B; motif: NGCCCNNRGGCA; match class: 1 0.029129277654073 1413 29 8 0.275862068965517 0.0056617126680821
TF TF:M00008_1 Factor: Sp1; motif: GGGGCGGGGT; match class: 1 0.0299958546927954 4937 110 43 0.390909090909091 0.00870974275876038
TF TF:M03567 Factor: Sp2; motif: NYSGCCCCGCCCCCY 0.0303093460476169 7710 143 75 0.524475524475524 0.00972762645914397
TF TF:M01045 Factor: AP-2alphaA; motif: ANNGCCTNAGGSNNT 0.0304671292462992 5875 45 24 0.533333333333333 0.00408510638297872
TF TF:M11601_1 Factor: TCF-1; motif: ACATCGRGRCGCTGW; match class: 1 0.0304671292462992 11053 80 59 0.7375 0.00533791730751832
TF TF:M09910_1 Factor: ER-beta; motif: RGGTCASCNTGMCCY; match class: 1 0.0314851823481932 4079 76 28 0.368421052631579 0.00686442755577347
TF TF:M07040 Factor: GKLF; motif: NNRRGRRNGNSNNN 0.0314851823481932 12705 143 110 0.769230769230769 0.00865800865800866
TF TF:M01131 Factor: Sox-10; motif: CWTTGTN 0.0314851823481932 8992 9 9 1 0.0010008896797153
TF TF:M03976 Factor: ERG; motif: ACCGGAWATCCGGT 0.0315008208326544 12803 77 63 0.818181818181818 0.00492072170585019
TF TF:M00665_1 Factor: Sp3; motif: ASMCTTGGGSRGGG; match class: 1 0.0315008208326544 2293 43 13 0.302325581395349 0.0056694286960314
TF TF:M12160_1 Factor: KLF15; motif: RCCMCRCCCMCN; match class: 1 0.0315008208326544 8031 134 73 0.544776119402985 0.00908977711368447
TF TF:M11230 Factor: CREBL1; motif: YGCCACGTCAYC 0.0315529325659534 56 66 3 0.0454545454545455 0.0535714285714286
TF TF:M11531 Factor: E2F-2; motif: GCGCGCGCGYW 0.0315529325659534 13270 75 63 0.84 0.00474755086661643
TF TF:M11595 Factor: GCMa; motif: RTGCGGGTN 0.0321792610821534 12117 140 104 0.742857142857143 0.00858298258644879
TF TF:M03978 Factor: ETS1; motif: GCCGGAWGTACTTCCGGN 0.0323556670048565 12082 72 57 0.791666666666667 0.00471776195994041
TF TF:M09739_1 Factor: ZGPAT; motif: GRGGCWGNGGNG; match class: 1 0.0323556670048565 2740 55 17 0.309090909090909 0.0062043795620438
TF TF:M10059_1 Factor: Smad2; motif: TGTCTGNCWCCT; match class: 1 0.0327245701974611 1258 8 4 0.5 0.00317965023847377
TF TF:M03882_1 Factor: RelB:p50; motif: RGAAANTCCCYNNHGC; match class: 1 0.0327245701974611 714 115 12 0.104347826086957 0.0168067226890756
TF TF:M11882 Factor: pax-6; motif: NYACGCNYSANYGMNCN 0.0327245701974611 15490 131 117 0.893129770992366 0.00755326016785023
TF TF:M01253 Factor: CNOT3; motif: GGCCGCGSSS 0.0327245701974611 3926 141 44 0.312056737588652 0.011207335710647
TF TF:M07277 Factor: BTEB2; motif: RGGGNGKGGN 0.0338314348152677 8492 128 73 0.5703125 0.00859632595383891
TF TF:M02078 Factor: SPI1; motif: NGRGGAAGTN 0.034107265756405 3506 4 4 1 0.00114090131203651
TF TF:M11697 Factor: MEF-2B1; motif: CCNWATWNRG 0.034107265756405 1096 22 6 0.272727272727273 0.00547445255474453
TF TF:M08205 Factor: E2F-1:Elk-1; motif: SGCGCSNNAMCGGAAGT 0.034107265756405 14429 77 68 0.883116883116883 0.00471273130501074
TF TF:M01857 Factor: AP-2alpha; motif: NGCCYSNNGSN 0.034107265756405 9178 81 52 0.641975308641975 0.0056657223796034
TF TF:M03846 Factor: SMAD5; motif: GSGGCAGM 0.0341798379957825 8552 86 52 0.604651162790698 0.00608044901777362
TF TF:M09918 Factor: Pet-1; motif: GCNGGAAGYG 0.0344820223190692 13610 137 111 0.81021897810219 0.00815576781778104
TF TF:M10112 Factor: Miz-1; motif: NNRGGWGGGGGAGGGGMRR 0.0344820223190692 8711 64 41 0.640625 0.00470669268740673
TF TF:M03971_1 Factor: ELK1; motif: NACTTCCGSCGGAAGYN; match class: 1 0.0344820223190692 7157 80 43 0.5375 0.00600810395417074
TF TF:M02105 Factor: NF-E4; motif: CHCCCTCKCCWG 0.0348323585938974 2647 137 32 0.233576642335766 0.0120891575368342
TF TF:M01104 Factor: MOVO-B; motif: GNGGGGG 0.0349132524975985 10261 143 93 0.65034965034965 0.00906344410876133
TF TF:M01595 Factor: STAT3; motif: NNTTCCRGGAANNNNN 0.0349132524975985 7736 13 11 0.846153846153846 0.00142192347466391
TF TF:M08819 Factor: LKLF; motif: CNCCACCCS 0.0349132524975985 5591 143 58 0.405594405594406 0.0103738150599177
TF TF:M00430_1 Factor: E2F-1; motif: NTTSGCGG; match class: 1 0.0349132524975985 2524 126 29 0.23015873015873 0.0114896988906498
TF TF:M12341 Factor: BCL-6; motif: NYGCTTTCKAGGAANN 0.0358337431962139 6051 93 43 0.462365591397849 0.00710626342753264
TF TF:M11528 Factor: E2F-2; motif: NTTTTGGCGCCAWWWN 0.0358337431962139 10373 80 56 0.7 0.00539863106140943
TF TF:M02075 Factor: PDEF; motif: MCCGGATNTN 0.0358337431962139 2666 120 29 0.241666666666667 0.0108777194298575
TF TF:M01256_1 Factor: REST; motif: NNNNGGNGCTGTCCATGGTGCT; match class: 1 0.03593403261373 246 17 3 0.176470588235294 0.0121951219512195
TF TF:M09610_1 Factor: ER-beta; motif: NRGGTCANKSTGACCTNN; match class: 1 0.0362268373529317 1574 7 4 0.571428571428571 0.00254129606099111
TF TF:M00800_1 Factor: AP-2; motif: GSCCSCRGGCNRNRNN; match class: 1 0.0362851704065121 4268 54 22 0.407407407407407 0.00515463917525773
TF TF:M00737_1 Factor: E2F-1:DP-2; motif: TTTSSCGC; match class: 1 0.0362851704065121 2933 44 15 0.340909090909091 0.00511421752471872
TF TF:M04106 Factor: RUNX2; motif: NRACCGCAAACCGCAN 0.0362851704065121 13833 77 66 0.857142857142857 0.00477119930600737
TF TF:M04849_1 Factor: RelA-p65; motif: AAASTCCC; match class: 1 0.0364893258338271 1170 9 4 0.444444444444444 0.00341880341880342
TF TF:M04595 Factor: SALL2; motif: GGGTGGG 0.0364893258338271 13013 141 110 0.780141843971631 0.0084530853761623
TF TF:M07355 Factor: GR; motif: AGAACAN 0.0364893258338271 5862 8 7 0.875 0.00119413169566701
TF TF:M03920 Factor: SP1; motif: RCCMCRCCCMC 0.0364893258338271 7283 143 71 0.496503496503497 0.00974872991898943
TF TF:M08306 Factor: GCMa:Elf-1; motif: NNCGGAARTGCKGGT 0.0364893258338271 2776 75 21 0.28 0.00756484149855908
TF TF:M08487_1 Factor: GCMa:Erg; motif: ATGCGGGCGGAARKG; match class: 1 0.0373060292006622 8790 77 48 0.623376623376623 0.00546075085324232
TF TF:M02023 Factor: MAZ; motif: NKGGGAGGGGRGGR 0.0373060292006622 7134 134 66 0.492537313432836 0.00925147182506308
TF TF:M05439 Factor: RREB-1; motif: GGGWCSA 0.0373432753870034 8635 125 72 0.576 0.00833815865662999
TF TF:M07206_1 Factor: E2F-1; motif: NGGGCGGGARV; match class: 1 0.0374522340899332 10849 68 50 0.735294117647059 0.00460871969766799
TF TF:M12158_1 Factor: KLF15; motif: NCCMCGCCCMCN; match class: 1 0.0374933063588661 6004 143 61 0.426573426573427 0.0101598934043971
TF TF:M05775 Factor: ZXDL; motif: NGGGGWS 0.038383714872931 6964 142 68 0.47887323943662 0.00976450315910396
TF TF:M09746_1 Factor: HNRPUL1; motif: NCNCAGN; match class: 1 0.038383714872931 7619 68 39 0.573529411764706 0.00511878199238745
TF TF:M02104 Factor: NF-E2; motif: CATGACTCAGCANNCN 0.0387995267594893 1146 47 9 0.191489361702128 0.00785340314136126
TF TF:M09591 Factor: AP-2gamma; motif: NTGSCCTGRGGSNN 0.0404192966366876 8337 46 30 0.652173913043478 0.00359841669665347
TF TF:M00737 Factor: E2F-1:DP-2; motif: TTTSSCGC 0.0407634560045996 8771 46 31 0.673913043478261 0.00353437464371223
TF TF:M00189 Factor: AP-2; motif: MKCCCSCNGGCG 0.0409146894753262 10621 128 86 0.671875 0.00809716599190283
TF TF:M08226_1 Factor: Elk-1:Pax-9; motif: ACCGGAACYACGCWYSANTG; match class: 1 0.0410809239206237 5604 59 28 0.474576271186441 0.00499643112062812
TF TF:M11395_1 Factor: Erg; motif: NACCGGAWWTCCGGTN; match class: 1 0.0424851374026508 7963 74 43 0.581081081081081 0.00539997488383775
TF TF:M01770 Factor: XBP-1; motif: WNNGMCACGTC 0.0427285096459872 11003 110 77 0.7 0.00699809142961011
TF TF:M00922 Factor: SRF; motif: CCAWATAWGGMNMNG 0.0427285096459872 291 16 3 0.1875 0.0103092783505155
TF TF:M09973 Factor: CPBP; motif: GNNRGGGHGGGGNNGGGRN 0.0427679284468877 10853 134 91 0.67910447761194 0.00838477840228508
TF TF:M09760 Factor: DPF2; motif: NYCACYTCCYCNYYCY 0.0429671177215458 8179 134 73 0.544776119402985 0.00892529649101357
TF TF:M01073 Factor: HIC1; motif: NNNGGKTGCCCSNNNNNN 0.0437731193624786 4088 139 44 0.316546762589928 0.0107632093933464
TF TF:M04515_1 Factor: E2F-1; motif: WWTGGCGCCAAA; match class: 1 0.0444558657044728 12173 135 100 0.740740740740741 0.00821490183192311
TF TF:M03876_1 Factor: Kaiso; motif: GCMGGGRGCRGS; match class: 1 0.0444697224296498 9106 143 84 0.587412587412587 0.00922468701954755
TF TF:M00189_1 Factor: AP-2; motif: MKCCCSCNGGCG; match class: 1 0.0444697224296498 6093 73 35 0.479452054794521 0.005744296733957
TF TF:M10086_1 Factor: TAFII250; motif: RARRWGGCGGMGGNGR; match class: 1 0.0444697224296498 4153 141 45 0.319148936170213 0.0108355405730797
TF TF:M01119_1 Factor: Kaiso; motif: NTCCTGCNAN; match class: 1 0.0448396044076737 542 32 5 0.15625 0.00922509225092251
TF TF:M11874 Factor: Pax-9; motif: NNGTCRCGCWTSANYGM 0.0450953800643727 409 42 5 0.119047619047619 0.0122249388753056
TF TF:M04726_1 Factor: REST; motif: GGACAGCKC; match class: 1 0.0458082860134538 1229 73 12 0.164383561643836 0.00976403580146461
TF TF:M04148 Factor: TFAP2A; motif: NGCCCYNNGGGCN 0.0458533537746946 10040 121 78 0.644628099173554 0.00776892430278884
TF TF:M08441_1 Factor: AP-2gamma:Elk-1; motif: NGCCKNRGGSGRCGGAAGTG; match class: 1 0.0461163464222836 12761 130 100 0.769230769230769 0.00783637645952511
TF TF:M11603 Factor: TCF-1; motif: ACATCGRGRCGCTGW 0.0461163464222836 16361 77 73 0.948051948051948 0.0044618299614938
TF TF:M03807 Factor: SP2; motif: GNNGGGGGCGGGGSN 0.0464117291203197 8415 48 31 0.645833333333333 0.00368389780154486
TF TF:M03896 Factor: EGR1; motif: NACGCCCACGCANW 0.0464849016200089 6129 123 54 0.439024390243902 0.00881057268722467
TF TF:M04826_1 Factor: p300; motif: ACNTCCG; match class: 1 0.046569362135522 15260 70 64 0.914285714285714 0.00419397116644823
TF TF:M11533_1 Factor: E2F-1; motif: NTTTTGGCGCCAWWWN; match class: 1 0.046569362135522 8705 94 56 0.595744680851064 0.0064330844342332
TF TF:M09898 Factor: Egr-2; motif: GNGRRNGWGKGGGNGGRG 0.0473407548714218 6484 48 26 0.541666666666667 0.0040098704503393
TF TF:M11397 Factor: Erg; motif: NACCGGATATCCGGTN 0.0474873581589419 12005 75 58 0.773333333333333 0.00483132028321533
TF TF:M04823_1 Factor: E2F-4; motif: NNTTCCCGCCNN; match class: 1 0.0482609457226199 7850 55 33 0.6 0.00420382165605096
TF TF:M01783 Factor: SP2; motif: GGGCGGGAC 0.0484896372629501 9148 143 84 0.587412587412587 0.00918233493659816
TF TF:M11018 Factor: IRX-1; motif: NACRYNNNNNNNNRYGNN 0.0489655147325103 16955 82 79 0.963414634146341 0.00465939250958419
TF TF:M09896_1 Factor: E2F-7; motif: GRGGCGGGAANNN; match class: 1 0.0489655147325103 4525 53 22 0.415094339622642 0.00486187845303867
TF TF:M11397_1 Factor: Erg; motif: NACCGGATATCCGGTN; match class: 1 0.0489655147325103 11731 75 57 0.76 0.00485892080811525
TF TF:M01860_1 Factor: AP-4; motif: NCAGCTGYNGNCN; match class: 1 0.0490730637264837 1669 126 21 0.166666666666667 0.0125823846614739
TF TF:M01240_1 Factor: BEN; motif: CAGCGRNV; match class: 1 0.0490730637264837 13227 143 112 0.783216783216783 0.00846752854010736
TF TF:M11533 Factor: E2F-1; motif: NTTTTGGCGCCAWWWN 0.0490730637264837 13105 133 104 0.781954887218045 0.00793590232735597
TF TF:M05949 Factor: ZNF714; motif: NGGGAAGGAAGM 0.0490730637264837 44 113 3 0.0265486725663717 0.0681818181818182
TF TF:M00777_1 Factor: STAT; motif: NNNNNTTCTKGGA; match class: 1 0.0490730637264837 797 7 3 0.428571428571429 0.00376411543287327
TF TF:M07348_1 Factor: AP-2alpha; motif: NSCCNCRGGSN; match class: 1 0.0490730637264837 2945 55 17 0.309090909090909 0.00577249575551783
TF TF:M11696_1 Factor: MEF-2B1; motif: CCNWATWWRG; match class: 1 0.0490730637264837 898 51 8 0.156862745098039 0.0089086859688196
TF TF:M08208 Factor: E2F-3:FOXI1; motif: NGACACCGCGCCCAC 0.0491964230894071 12560 67 54 0.805970149253731 0.00429936305732484
TF TF:M04934_1 Factor: TR4; motif: ACCCCGS; match class: 1 0.0492042287691434 15478 143 126 0.881118881118881 0.00814058663910066
TF TF:M11811 Factor: PPARdelta; motif: NRRGGTCGYGACCYYN 0.0493043699824252 403 27 4 0.148148148148148 0.00992555831265509
WP WP:WP2911 miRNA targets in ECM and membrane receptors 5.30197270771529e-16 43 44 12 0.272727272727273 0.27906976744186
WP WP:WP4786 Type I collagen synthesis in the context of Osteogenesis imperfecta 8.68026860940279e-16 33 117 14 0.11965811965812 0.424242424242424
WP WP:WP3967 miR-509-3p alteration of YAP1/ECM axis 1.43075268240952e-10 19 8 5 0.625 0.263157894736842
WP WP:WP453 Inflammatory Response Pathway 1.0266058898016e-08 33 4 4 1 0.121212121212121
WP WP:WP306 Focal Adhesion 2.2823744201071e-08 201 44 12 0.272727272727273 0.0597014925373134
WP WP:WP3932 Focal Adhesion-PI3K-Akt-mTOR-signaling pathway 2.2823744201071e-08 309 44 14 0.318181818181818 0.0453074433656958
WP WP:WP4172 PI3K-Akt Signaling Pathway 7.25934633857154e-06 345 44 12 0.272727272727273 0.0347826086956522
WP WP:WP4754 IL-18 signaling pathway 3.0993080155422e-05 279 4 4 1 0.014336917562724
WP WP:WP615 Senescence and Autophagy in Cancer 4.0022534114011e-05 108 8 4 0.5 0.037037037037037
WP WP:WP3874 Canonical and Non-Canonical TGF-B signaling 6.05293038413135e-05 17 52 4 0.0769230769230769 0.235294117647059
WP WP:WP4658 Small cell lung cancer 0.00172268093961013 98 40 5 0.125 0.0510204081632653
WP WP:WP2572 Primary Focal Segmental Glomerulosclerosis FSGS 0.00577663913387461 74 40 4 0.1 0.0540540540540541
WP WP:WP366 TGF-beta Signaling Pathway 0.0102509534842033 133 28 4 0.142857142857143 0.0300751879699248
WP WP:WP129 Matrix Metalloproteinases 0.0127423822714673 30 135 4 0.0296296296296296 0.133333333333333
WP WP:WP2865 IL1 and megakaryocytes in obesity 0.0265048277503948 25 99 3 0.0303030303030303 0.12
WP WP:WP1982 Sterol Regulatory Element-Binding Proteins (SREBP) signalling 0.0434046662264588 73 82 4 0.0487804878048781 0.0547945205479452

pS08 transcription factor target enrichment of top program genes

TF enrichment of pS08
TFs corrosponding to activation of pS08. (Left) pearson correlation of TF expression and gene expression program activatity in Stromal cells, (right) negative log p-value for enrichment of TF binding sites among top uniqueness weighted genes for the gene program. Blue bars indicate significant TFs meeting the following criteria: FDR<0.1, overlap > 2, Corr. R > 0, permutation based p-value < 0.05.