pEpi04 program activity among Epithelial cells

Activation of pEpi04
pEpi04 gene program activation in Epithelial cells. (Top) Activation of program across all epithelial cells. (Bottom) Activation in MMRd (left), MMRp (middle), and normal epithelial cells (right).

Epithelial cell compositional overview

Overview of epithelial cell composition
Overview of epithelial cell composition. A tSNE plot colored by: (left) MMR status of epithelial cells, (middle) specimen, (righ) epithelial cell sub-type.
Gene program activation of pEpi04 by different cell subtypes
pEpi04 gene program activation among cells of different subtypes (Epithelial cells).

pEpi04 top program genes

Top genes of pEpi04 program
Bar plots showing the top genes for each gene program, ranked by (left) unique weights, (right) raw weights.

pEpi04 gene-set enrichment of top program genes (using g-profiler)

GSEA wth gene profiler of pEpi04
pEpi04 gene-set enrichment summary using g-profiler webtool.
Source termID Name Padj Tsize Qsize Overlap Precision Recall
CORUM CORUM:6131 SELK multiprotein complex 0.0321200042922592 10 101 3 0.0297029702970297 0.3
GO:BP GO:0016126 sterol biosynthetic process 5.13851874451823e-37 80 115 27 0.234782608695652 0.3375
GO:BP GO:0006695 cholesterol biosynthetic process 1.5284494827025e-36 74 115 26 0.226086956521739 0.351351351351351
GO:BP GO:1902653 secondary alcohol biosynthetic process 1.5284494827025e-36 74 115 26 0.226086956521739 0.351351351351351
GO:BP GO:1902652 secondary alcohol metabolic process 8.14467280699898e-30 164 115 28 0.243478260869565 0.170731707317073
GO:BP GO:0016125 sterol metabolic process 1.43166562919135e-29 171 35 20 0.571428571428571 0.116959064327485
GO:BP GO:0006694 steroid biosynthetic process 2.95200700456569e-29 196 115 29 0.252173913043478 0.147959183673469
GO:BP GO:0008203 cholesterol metabolic process 3.17074758064387e-29 154 115 27 0.234782608695652 0.175324675324675
GO:BP GO:0046165 alcohol biosynthetic process 2.38825306030236e-27 158 115 26 0.226086956521739 0.164556962025316
GO:BP GO:0008202 steroid metabolic process 1.69610054820752e-25 342 35 21 0.6 0.0614035087719298
GO:BP GO:0045540 regulation of cholesterol biosynthetic process 2.39855964957301e-25 50 115 18 0.156521739130435 0.36
GO:BP GO:0106118 regulation of sterol biosynthetic process 2.39855964957301e-25 50 115 18 0.156521739130435 0.36
GO:BP GO:1901617 organic hydroxy compound biosynthetic process 9.14398917109217e-25 254 115 28 0.243478260869565 0.110236220472441
GO:BP GO:0044283 small molecule biosynthetic process 3.13902576260262e-24 704 115 39 0.339130434782609 0.0553977272727273
GO:BP GO:0008610 lipid biosynthetic process 1.84431046920084e-23 740 115 39 0.339130434782609 0.0527027027027027
GO:BP GO:0090181 regulation of cholesterol metabolic process 3.26738958922793e-23 64 115 18 0.156521739130435 0.28125
GO:BP GO:0050810 regulation of steroid biosynthetic process 5.65502541110095e-23 97 115 20 0.173913043478261 0.206185567010309
GO:BP GO:0006066 alcohol metabolic process 6.52554824565394e-23 382 35 20 0.571428571428571 0.0523560209424084
GO:BP GO:0046890 regulation of lipid biosynthetic process 1.20488894193267e-22 215 115 25 0.217391304347826 0.116279069767442
GO:BP GO:1902930 regulation of alcohol biosynthetic process 1.4174753973231e-21 78 115 18 0.156521739130435 0.230769230769231
GO:BP GO:1901615 organic hydroxy compound metabolic process 3.91580230739604e-21 571 35 21 0.6 0.0367775831873905
GO:BP GO:0019218 regulation of steroid metabolic process 2.24273142696627e-20 130 115 20 0.173913043478261 0.153846153846154
GO:BP GO:0019216 regulation of lipid metabolic process 1.01882712925649e-16 419 115 26 0.226086956521739 0.0620525059665871
GO:BP GO:0006629 lipid metabolic process 1.97940782770302e-15 1457 35 23 0.657142857142857 0.0157858613589568
GO:BP GO:0062012 regulation of small molecule metabolic process 5.575270056751e-15 447 115 25 0.217391304347826 0.0559284116331096
GO:BP GO:0044281 small molecule metabolic process 9.87977198444919e-14 1921 115 45 0.391304347826087 0.0234252993232691
GO:BP GO:0046949 fatty-acyl-CoA biosynthetic process 1.55125095393411e-13 31 109 10 0.0917431192660551 0.32258064516129
GO:BP GO:0034976 response to endoplasmic reticulum stress 4.52393595469764e-12 298 101 18 0.178217821782178 0.0604026845637584
GO:BP GO:0035337 fatty-acyl-CoA metabolic process 4.52393595469764e-12 42 109 10 0.0917431192660551 0.238095238095238
GO:BP GO:0035383 thioester metabolic process 4.72846459225205e-12 105 109 13 0.119266055045872 0.123809523809524
GO:BP GO:0006637 acyl-CoA metabolic process 4.72846459225205e-12 105 109 13 0.119266055045872 0.123809523809524
GO:BP GO:0033865 nucleoside bisphosphate metabolic process 9.95401893888858e-12 141 109 14 0.128440366972477 0.099290780141844
GO:BP GO:0034032 purine nucleoside bisphosphate metabolic process 9.95401893888858e-12 141 109 14 0.128440366972477 0.099290780141844
GO:BP GO:0033875 ribonucleoside bisphosphate metabolic process 9.95401893888858e-12 141 109 14 0.128440366972477 0.099290780141844
GO:BP GO:0034975 protein folding in endoplasmic reticulum 3.76375186970278e-11 11 61 6 0.0983606557377049 0.545454545454545
GO:BP GO:0044255 cellular lipid metabolic process 4.94849831763818e-11 1075 109 30 0.275229357798165 0.027906976744186
GO:BP GO:0035384 thioester biosynthetic process 5.24455406564034e-11 54 109 10 0.0917431192660551 0.185185185185185
GO:BP GO:0071616 acyl-CoA biosynthetic process 5.24455406564034e-11 54 109 10 0.0917431192660551 0.185185185185185
GO:BP GO:1901570 fatty acid derivative biosynthetic process 1.85829081379133e-10 61 109 10 0.0917431192660551 0.163934426229508
GO:BP GO:0055114 obsolete oxidation-reduction process 4.95188649827188e-10 745 73 20 0.273972602739726 0.0268456375838926
GO:BP GO:0033490 cholesterol biosynthetic process via lathosterol 4.95188649827188e-10 4 32 4 0.125 1
GO:BP GO:0033489 cholesterol biosynthetic process via desmosterol 4.95188649827188e-10 4 32 4 0.125 1
GO:BP GO:0033866 nucleoside bisphosphate biosynthetic process 4.99708279578107e-10 68 109 10 0.0917431192660551 0.147058823529412
GO:BP GO:0034030 ribonucleoside bisphosphate biosynthetic process 4.99708279578107e-10 68 109 10 0.0917431192660551 0.147058823529412
GO:BP GO:0034033 purine nucleoside bisphosphate biosynthetic process 4.99708279578107e-10 68 109 10 0.0917431192660551 0.147058823529412
GO:BP GO:0008299 isoprenoid biosynthetic process 5.52733128823179e-10 29 67 7 0.104477611940299 0.241379310344828
GO:BP GO:0006633 fatty acid biosynthetic process 1.59069743051326e-09 170 109 13 0.119266055045872 0.0764705882352941
GO:BP GO:0035966 response to topologically incorrect protein 2.76907139274935e-09 205 76 12 0.157894736842105 0.0585365853658537
GO:BP GO:1901568 fatty acid derivative metabolic process 2.77360486238371e-09 81 109 10 0.0917431192660551 0.123456790123457
GO:BP GO:0072330 monocarboxylic acid biosynthetic process 4.20596966998446e-09 226 109 14 0.128440366972477 0.0619469026548673
GO:BP GO:0035967 cellular response to topologically incorrect protein 5.29327986707336e-09 168 76 11 0.144736842105263 0.0654761904761905
GO:BP GO:0006720 isoprenoid metabolic process 1.25036254778322e-08 144 35 8 0.228571428571429 0.0555555555555556
GO:BP GO:0006986 response to unfolded protein 1.35256678654244e-08 184 76 11 0.144736842105263 0.0597826086956522
GO:BP GO:0006631 fatty acid metabolic process 1.39773804197439e-08 404 109 17 0.155963302752294 0.0420792079207921
GO:BP GO:0045338 farnesyl diphosphate metabolic process 1.62160999669945e-08 5 7 3 0.428571428571429 0.6
GO:BP GO:0034620 cellular response to unfolded protein 2.82644171983802e-08 149 76 10 0.131578947368421 0.0671140939597315
GO:BP GO:0070972 protein localization to endoplasmic reticulum 2.95566512374207e-08 146 78 10 0.128205128205128 0.0684931506849315
GO:BP GO:0035338 long-chain fatty-acyl-CoA biosynthetic process 4.57175598354106e-08 19 109 6 0.055045871559633 0.315789473684211
GO:BP GO:0046394 carboxylic acid biosynthetic process 5.43764482478907e-08 330 109 15 0.137614678899083 0.0454545454545455
GO:BP GO:0016053 organic acid biosynthetic process 7.41777572044489e-08 338 109 15 0.137614678899083 0.0443786982248521
GO:BP GO:0032787 monocarboxylic acid metabolic process 8.60295595541059e-08 658 109 20 0.18348623853211 0.0303951367781155
GO:BP GO:0030968 endoplasmic reticulum unfolded protein response 9.85350893557288e-08 128 101 10 0.099009900990099 0.078125
GO:BP GO:0090407 organophosphate biosynthetic process 1.07719078921691e-07 598 109 19 0.174311926605505 0.0317725752508361
GO:BP GO:0010033 response to organic substance 1.4727325293602e-07 3412 70 35 0.5 0.0102579132473623
GO:BP GO:0035336 long-chain fatty-acyl-CoA metabolic process 2.58102426127178e-07 25 109 6 0.055045871559633 0.24
GO:BP GO:0019637 organophosphate metabolic process 3.72086895210472e-07 1041 109 24 0.220183486238532 0.0230547550432277
GO:BP GO:0009152 purine ribonucleotide biosynthetic process 4.01041123772978e-07 179 109 11 0.100917431192661 0.0614525139664804
GO:BP GO:1901362 organic cyclic compound biosynthetic process 5.55274984294227e-07 4439 18 16 0.888888888888889 0.00360441540887587
GO:BP GO:0009260 ribonucleotide biosynthetic process 8.06116359898126e-07 192 109 11 0.100917431192661 0.0572916666666667
GO:BP GO:0009150 purine ribonucleotide metabolic process 9.68497956400303e-07 414 109 15 0.137614678899083 0.036231884057971
GO:BP GO:0045047 protein targeting to ER 1.03032179154072e-06 113 78 8 0.102564102564103 0.0707964601769911
GO:BP GO:0006984 ER-nucleus signaling pathway 1.07294130686297e-06 53 110 7 0.0636363636363636 0.132075471698113
GO:BP GO:0046390 ribose phosphate biosynthetic process 1.10160439214231e-06 199 109 11 0.100917431192661 0.0552763819095477
GO:BP GO:0006084 acetyl-CoA metabolic process 1.25950417057851e-06 38 93 6 0.0645161290322581 0.157894736842105
GO:BP GO:0006164 purine nucleotide biosynthetic process 1.25950417057851e-06 202 109 11 0.100917431192661 0.0544554455445545
GO:BP GO:0072599 establishment of protein localization to endoplasmic reticulum 1.26396186954036e-06 117 78 8 0.102564102564103 0.0683760683760684
GO:BP GO:0009259 ribonucleotide metabolic process 1.49368182901366e-06 431 109 15 0.137614678899083 0.0348027842227378
GO:BP GO:0006457 protein folding 1.9100367899027e-06 225 61 9 0.147540983606557 0.04
GO:BP GO:0019693 ribose phosphate metabolic process 1.96510544761343e-06 441 109 15 0.137614678899083 0.0340136054421769
GO:BP GO:0072522 purine-containing compound biosynthetic process 2.01544743672203e-06 213 109 11 0.100917431192661 0.0516431924882629
GO:BP GO:0006163 purine nucleotide metabolic process 2.46260737646244e-06 450 109 15 0.137614678899083 0.0333333333333333
GO:BP GO:0006790 sulfur compound metabolic process 2.46260737646244e-06 386 109 14 0.128440366972477 0.0362694300518135
GO:BP GO:0019752 carboxylic acid metabolic process 4.57818913942908e-06 1024 109 22 0.201834862385321 0.021484375
GO:BP GO:0072521 purine-containing compound metabolic process 4.57818913942908e-06 473 109 15 0.137614678899083 0.0317124735729387
GO:BP GO:1905897 regulation of response to endoplasmic reticulum stress 4.57818913942908e-06 84 87 7 0.0804597701149425 0.0833333333333333
GO:BP GO:0044272 sulfur compound biosynthetic process 7.34983508745295e-06 193 109 10 0.0917431192660551 0.0518134715025907
GO:BP GO:0043436 oxoacid metabolic process 7.63164247918246e-06 1057 109 22 0.201834862385321 0.0208136234626301
GO:BP GO:0036498 IRE1-mediated unfolded protein response 1.02350573584165e-05 67 76 6 0.0789473684210526 0.0895522388059701
GO:BP GO:0006082 organic acid metabolic process 1.25983661622745e-05 1090 109 22 0.201834862385321 0.0201834862385321
GO:BP GO:0046490 isopentenyl diphosphate metabolic process 1.31054182930907e-05 5 67 3 0.0447761194029851 0.6
GO:BP GO:0009240 isopentenyl diphosphate biosynthetic process 1.31054182930907e-05 5 67 3 0.0447761194029851 0.6
GO:BP GO:1900222 negative regulation of amyloid-beta clearance 1.32416500449455e-05 11 115 4 0.0347826086956522 0.363636363636364
GO:BP GO:0006636 unsaturated fatty acid biosynthetic process 1.59107313067243e-05 51 109 6 0.055045871559633 0.117647058823529
GO:BP GO:0009165 nucleotide biosynthetic process 1.76484799414302e-05 269 109 11 0.100917431192661 0.0408921933085502
GO:BP GO:1901293 nucleoside phosphate biosynthetic process 2.01973019144828e-05 273 109 11 0.100917431192661 0.0402930402930403
GO:BP GO:0042221 response to chemical 2.0778600289009e-05 4781 102 50 0.490196078431373 0.0104580631667015
GO:BP GO:0036109 alpha-linolenic acid metabolic process 2.17353523455334e-05 13 109 4 0.036697247706422 0.307692307692308
GO:BP GO:0009117 nucleotide metabolic process 2.29201806661757e-05 544 109 15 0.137614678899083 0.0275735294117647
GO:BP GO:0036503 ERAD pathway 2.57792908150332e-05 103 59 6 0.101694915254237 0.058252427184466
GO:BP GO:0006753 nucleoside phosphate metabolic process 2.88313897901379e-05 555 109 15 0.137614678899083 0.027027027027027
GO:BP GO:1901360 organic cyclic compound metabolic process 6.00238142477783e-05 6201 18 16 0.888888888888889 0.00258022899532333
GO:BP GO:0051649 establishment of localization in cell 6.04408310381377e-05 2813 78 29 0.371794871794872 0.0103092783505155
GO:BP GO:1903573 negative regulation of response to endoplasmic reticulum stress 6.36440786548644e-05 46 87 5 0.0574712643678161 0.108695652173913
GO:BP GO:1901576 organic substance biosynthetic process 6.53340255530548e-05 6248 18 16 0.888888888888889 0.00256081946222791
GO:BP GO:0006605 protein targeting 6.58677253955139e-05 441 78 11 0.141025641025641 0.0249433106575964
GO:BP GO:0016114 terpenoid biosynthetic process 6.85559885633367e-05 15 35 3 0.0857142857142857 0.2
GO:BP GO:0009058 biosynthetic process 7.91488344660392e-05 6340 18 16 0.888888888888889 0.00252365930599369
GO:BP GO:0006721 terpenoid metabolic process 8.26461460243046e-05 123 35 5 0.142857142857143 0.040650406504065
GO:BP GO:0006613 cotranslational protein targeting to membrane 0.000112504276623868 102 78 6 0.0769230769230769 0.0588235294117647
GO:BP GO:0046907 intracellular transport 0.000112504276623868 1767 110 27 0.245454545454545 0.0152801358234295
GO:BP GO:0055086 nucleobase-containing small molecule metabolic process 0.000118169600609417 629 109 15 0.137614678899083 0.0238473767885533
GO:BP GO:1900221 regulation of amyloid-beta clearance 0.000120683713764544 19 115 4 0.0347826086956522 0.210526315789474
GO:BP GO:0033559 unsaturated fatty acid metabolic process 0.000137361754678773 116 109 7 0.0642201834862385 0.0603448275862069
GO:BP GO:0030433 ubiquitin-dependent ERAD pathway 0.000137361754678773 82 101 6 0.0594059405940594 0.0731707317073171
GO:BP GO:0043651 linoleic acid metabolic process 0.000143787767010542 21 109 4 0.036697247706422 0.19047619047619
GO:BP GO:0006644 phospholipid metabolic process 0.000143787767010542 427 105 12 0.114285714285714 0.0281030444964871
GO:BP GO:0032527 protein exit from endoplasmic reticulum 0.000143787767010542 48 101 5 0.0495049504950495 0.104166666666667
GO:BP GO:0034625 fatty acid elongation, monounsaturated fatty acid 0.000146900594372693 7 109 3 0.0275229357798165 0.428571428571429
GO:BP GO:0019367 fatty acid elongation, saturated fatty acid 0.000146900594372693 7 109 3 0.0275229357798165 0.428571428571429
GO:BP GO:0034626 fatty acid elongation, polyunsaturated fatty acid 0.000146900594372693 7 109 3 0.0275229357798165 0.428571428571429
GO:BP GO:0019368 fatty acid elongation, unsaturated fatty acid 0.000146900594372693 7 109 3 0.0275229357798165 0.428571428571429
GO:BP GO:0048193 Golgi vesicle transport 0.000184597326266786 382 101 11 0.108910891089109 0.0287958115183246
GO:BP GO:0071702 organic substance transport 0.000222228591996814 2766 115 36 0.31304347826087 0.0130151843817787
GO:BP GO:0035437 maintenance of protein localization in endoplasmic reticulum 0.000279371584929638 14 63 3 0.0476190476190476 0.214285714285714
GO:BP GO:1901135 carbohydrate derivative metabolic process 0.000279523153581893 1145 109 20 0.18348623853211 0.0174672489082969
GO:BP GO:1901137 carbohydrate derivative biosynthetic process 0.000292794821730492 686 109 15 0.137614678899083 0.021865889212828
GO:BP GO:1903513 endoplasmic reticulum to cytosol transport 0.000320650937018616 28 101 4 0.0396039603960396 0.142857142857143
GO:BP GO:0030970 retrograde protein transport, ER to cytosol 0.000320650937018616 28 101 4 0.0396039603960396 0.142857142857143
GO:BP GO:0006888 endoplasmic reticulum to Golgi vesicle-mediated transport 0.000377479400472548 206 101 8 0.0792079207920792 0.0388349514563107
GO:BP GO:0070887 cellular response to chemical stimulus 0.000413160924043269 3393 102 37 0.362745098039216 0.0109048040082523
GO:BP GO:0006612 protein targeting to membrane 0.000518660529054586 204 78 7 0.0897435897435897 0.0343137254901961
GO:BP GO:0008654 phospholipid biosynthetic process 0.000527095794771819 274 104 9 0.0865384615384615 0.0328467153284672
GO:BP GO:0033554 cellular response to stress 0.000532071658599978 2111 91 25 0.274725274725275 0.0118427285646613
GO:BP GO:0006820 anion transport 0.00053890575240078 2889 115 36 0.31304347826087 0.0124610591900312
GO:BP GO:0051641 cellular localization 0.000542194530945074 3541 78 31 0.397435897435897 0.00875458909912454
GO:BP GO:0071310 cellular response to organic substance 0.000620314795129921 2776 102 32 0.313725490196078 0.0115273775216138
GO:BP GO:0071705 nitrogen compound transport 0.000626525345332591 2322 115 31 0.269565217391304 0.0133505598621878
GO:BP GO:0006886 intracellular protein transport 0.000659998414188195 1186 78 16 0.205128205128205 0.0134907251264755
GO:BP GO:0015031 protein transport 0.000737710911789994 1929 72 20 0.277777777777778 0.0103680663556247
GO:BP GO:0043603 cellular amide metabolic process 0.000897336010255001 1241 93 18 0.193548387096774 0.0145044319097502
GO:BP GO:0000038 very long-chain fatty acid metabolic process 0.000954986936417724 35 109 4 0.036697247706422 0.114285714285714
GO:BP GO:0042761 very long-chain fatty acid biosynthetic process 0.000960880380583087 13 109 3 0.0275229357798165 0.230769230769231
GO:BP GO:0030163 protein catabolic process 0.000960880380583087 974 59 12 0.203389830508475 0.0123203285420945
GO:BP GO:0030497 fatty acid elongation 0.000960880380583087 13 109 3 0.0275229357798165 0.230769230769231
GO:BP GO:0006614 SRP-dependent cotranslational protein targeting to membrane 0.000960880380583087 96 78 5 0.0641025641025641 0.0520833333333333
GO:BP GO:0015833 peptide transport 0.000960880380583087 1971 72 20 0.277777777777778 0.0101471334348047
GO:BP GO:0001676 long-chain fatty acid metabolic process 0.000961116411044537 112 109 6 0.055045871559633 0.0535714285714286
GO:BP GO:0006810 transport 0.000968179199160792 5224 83 41 0.493975903614458 0.00784839203675344
GO:BP GO:0080135 regulation of cellular response to stress 0.00105160153908413 725 91 13 0.142857142857143 0.0179310344827586
GO:BP GO:0044238 primary metabolic process 0.00109854558919963 10584 32 29 0.90625 0.00273998488284203
GO:BP GO:0016192 vesicle-mediated transport 0.00114976362648409 2180 77 22 0.285714285714286 0.0100917431192661
GO:BP GO:0042886 amide transport 0.00116420284318227 2007 72 20 0.277777777777778 0.00996512207274539
GO:BP GO:0009889 regulation of biosynthetic process 0.00123817528427805 4361 9 8 0.888888888888889 0.00183444164182527
GO:BP GO:0060548 negative regulation of cell death 0.00127608473275081 1038 114 18 0.157894736842105 0.0173410404624277
GO:BP GO:0120178 steroid hormone biosynthetic process 0.00129693017310774 50 31 3 0.0967741935483871 0.06
GO:BP GO:0045184 establishment of protein localization 0.00137903061708503 2035 72 20 0.277777777777778 0.00982800982800983
GO:BP GO:0097242 amyloid-beta clearance 0.0014646434938632 38 115 4 0.0347826086956522 0.105263157894737
GO:BP GO:1901701 cellular response to oxygen-containing compound 0.00168445343559771 1227 30 9 0.3 0.00733496332518337
GO:BP GO:1902236 negative regulation of endoplasmic reticulum stress-induced intrinsic apoptotic signaling pathway 0.00169673257215185 20 87 3 0.0344827586206897 0.15
GO:BP GO:0036499 PERK-mediated unfolded protein response 0.00173560103645007 23 76 3 0.0394736842105263 0.130434782608696
GO:BP GO:0051234 establishment of localization 0.00173611629446936 5372 83 41 0.493975903614458 0.00763216679076694
GO:BP GO:0090150 establishment of protein localization to membrane 0.00190364993609582 351 78 8 0.102564102564103 0.0227920227920228
GO:BP GO:0010941 regulation of cell death 0.00214863018310044 1720 114 24 0.210526315789474 0.013953488372093
GO:BP GO:1901700 response to oxygen-containing compound 0.00230092985007182 1739 33 11 0.333333333333333 0.00632547441058079
GO:BP GO:0033036 macromolecule localization 0.00235523882002747 3218 80 28 0.35 0.00870105655686762
GO:BP GO:0045454 cell redox homeostasis 0.00241967586889065 58 87 4 0.0459770114942529 0.0689655172413793
GO:BP GO:0010498 proteasomal protein catabolic process 0.00252286090715477 491 59 8 0.135593220338983 0.0162932790224033
GO:BP GO:0140467 integrated stress response signaling 0.0026739320443978 27 76 3 0.0394736842105263 0.111111111111111
GO:BP GO:0072594 establishment of protein localization to organelle 0.00270785194837448 584 78 10 0.128205128205128 0.0171232876712329
GO:BP GO:0065008 regulation of biological quality 0.00307040885704925 4131 114 43 0.37719298245614 0.0104091019123699
GO:BP GO:0006890 retrograde vesicle-mediated transport, Golgi to endoplasmic reticulum 0.0031743311494713 87 63 4 0.0634920634920635 0.0459770114942529
GO:BP GO:0070059 intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress 0.0031743311494713 63 87 4 0.0459770114942529 0.0634920634920635
GO:BP GO:0042446 hormone biosynthetic process 0.0031779001892051 71 31 3 0.0967741935483871 0.0422535211267606
GO:BP GO:0044257 cellular protein catabolic process 0.00350448451017248 813 59 10 0.169491525423729 0.01230012300123
GO:BP GO:0043069 negative regulation of programmed cell death 0.00355094006957796 943 114 16 0.140350877192982 0.0169671261930011
GO:BP GO:0042632 cholesterol homeostasis 0.00368556016691733 99 58 4 0.0689655172413793 0.0404040404040404
GO:BP GO:0055092 sterol homeostasis 0.0038100703188989 100 58 4 0.0689655172413793 0.04
GO:BP GO:0043067 regulation of programmed cell death 0.00401165180214807 1582 114 22 0.192982456140351 0.0139064475347661
GO:BP GO:0051235 maintenance of location 0.00421410296745792 337 8 3 0.375 0.00890207715133531
GO:BP GO:0010256 endomembrane system organization 0.00421410296745792 484 82 9 0.109756097560976 0.0185950413223141
GO:BP GO:0042304 regulation of fatty acid biosynthetic process 0.00421410296745792 57 105 4 0.0380952380952381 0.0701754385964912
GO:BP GO:0071704 organic substance metabolic process 0.00461397636767545 11326 32 29 0.90625 0.00256048031078933
GO:BP GO:0097006 regulation of plasma lipoprotein particle levels 0.00487817906637956 107 105 5 0.0476190476190476 0.0467289719626168
GO:BP GO:0140354 lipid import into cell 0.00576028184575231 35 80 3 0.0375 0.0857142857142857
GO:BP GO:0007029 endoplasmic reticulum organization 0.00576028184575231 87 76 4 0.0526315789473684 0.0459770114942529
GO:BP GO:0043161 proteasome-mediated ubiquitin-dependent protein catabolic process 0.00587438335718609 434 59 7 0.11864406779661 0.0161290322580645
GO:BP GO:1902235 regulation of endoplasmic reticulum stress-induced intrinsic apoptotic signaling pathway 0.00609389232020292 33 87 3 0.0344827586206897 0.0909090909090909
GO:BP GO:0055088 lipid homeostasis 0.00628330740524164 167 110 6 0.0545454545454545 0.0359281437125748
GO:BP GO:0042445 hormone metabolic process 0.00666614494492068 228 31 4 0.129032258064516 0.0175438596491228
GO:BP GO:1901698 response to nitrogen compound 0.00666970014003529 1172 46 10 0.217391304347826 0.00853242320819113
GO:BP GO:0042981 regulation of apoptotic process 0.00682642481865936 1549 114 21 0.184210526315789 0.013557133634603
GO:BP GO:0051603 proteolysis involved in cellular protein catabolic process 0.0073945847313011 750 59 9 0.152542372881356 0.012
GO:BP GO:0032387 negative regulation of intracellular transport 0.00760287284669082 57 55 3 0.0545454545454545 0.0526315789473684
GO:BP GO:1903792 negative regulation of anion transport 0.00829021332039841 235 115 7 0.0608695652173913 0.0297872340425532
GO:BP GO:0007030 Golgi organization 0.00841059067140989 147 51 4 0.0784313725490196 0.0272108843537415
GO:BP GO:0006811 ion transport 0.00856087095652775 3661 81 29 0.358024691358025 0.00792133296913412
GO:BP GO:0008104 protein localization 0.0085810192792432 2770 72 22 0.305555555555556 0.00794223826714801
GO:BP GO:0120254 olefinic compound metabolic process 0.00876226753069812 121 109 5 0.0458715596330275 0.0413223140495868
GO:BP GO:0046337 phosphatidylethanolamine metabolic process 0.00876226753069812 32 105 3 0.0285714285714286 0.09375
GO:BP GO:0008219 cell death 0.00879894301011824 2292 114 27 0.236842105263158 0.0117801047120419
GO:BP GO:0009057 macromolecule catabolic process 0.00894863378438757 1468 115 20 0.173913043478261 0.0136239782016349
GO:BP GO:0080090 regulation of primary metabolic process 0.00894863378438757 6053 18 13 0.722222222222222 0.00214769535767388
GO:BP GO:0014074 response to purine-containing compound 0.00913902604390972 152 23 3 0.130434782608696 0.0197368421052632
GO:BP GO:0043604 amide biosynthetic process 0.00928813414524325 932 93 13 0.139784946236559 0.0139484978540773
GO:BP GO:0015909 long-chain fatty acid transport 0.00936599962194316 75 105 4 0.0380952380952381 0.0533333333333333
GO:BP GO:1901566 organonitrogen compound biosynthetic process 0.00970995226298972 1853 93 20 0.21505376344086 0.0107933081489477
GO:BP GO:0014070 response to organic cyclic compound 0.0101247674974905 967 23 6 0.260869565217391 0.0062047569803516
GO:BP GO:0008152 metabolic process 0.0101704297084056 11827 32 29 0.90625 0.00245201657224994
GO:BP GO:0042592 homeostatic process 0.0101704297084056 1981 94 21 0.223404255319149 0.0106007067137809
GO:BP GO:0033993 response to lipid 0.0113649886485161 918 5 3 0.6 0.00326797385620915
GO:BP GO:0033365 protein localization to organelle 0.0116023193277596 1017 110 15 0.136363636363636 0.0147492625368732
GO:BP GO:1901565 organonitrogen compound catabolic process 0.0116059437023668 1358 59 12 0.203389830508475 0.00883652430044183
GO:BP GO:0010243 response to organonitrogen compound 0.0117086501817461 1085 83 13 0.156626506024096 0.0119815668202765
GO:BP GO:0006915 apoptotic process 0.0117086501817461 1990 114 24 0.210526315789474 0.0120603015075377
GO:BP GO:0120162 positive regulation of cold-induced thermogenesis 0.0126977830262821 97 90 4 0.0444444444444444 0.0412371134020619
GO:BP GO:0006900 vesicle budding from membrane 0.0134689135524442 107 83 4 0.0481927710843374 0.0373831775700935
GO:BP GO:0051224 negative regulation of protein transport 0.0134889640693146 135 66 4 0.0606060606060606 0.0296296296296296
GO:BP GO:0012501 programmed cell death 0.0139948689266791 2143 114 25 0.219298245614035 0.0116658889407373
GO:BP GO:1904950 negative regulation of establishment of protein localization 0.0146609048983166 139 66 4 0.0606060606060606 0.0287769784172662
GO:BP GO:0032365 intracellular lipid transport 0.014847360783635 46 93 3 0.032258064516129 0.0652173913043478
GO:BP GO:0046889 positive regulation of lipid biosynthetic process 0.0149346751283184 88 105 4 0.0380952380952381 0.0454545454545455
GO:BP GO:0006641 triglyceride metabolic process 0.0150234470063404 113 82 4 0.0487804878048781 0.0353982300884956
GO:BP GO:0034754 cellular hormone metabolic process 0.0150243441632334 140 31 3 0.0967741935483871 0.0214285714285714
GO:BP GO:0034613 cellular protein localization 0.0161860817598512 2014 78 18 0.230769230769231 0.00893743793445879
GO:BP GO:0043066 negative regulation of apoptotic process 0.0161860817598512 921 114 14 0.12280701754386 0.0152008686210641
GO:BP GO:2001238 positive regulation of extrinsic apoptotic signaling pathway 0.0164265606888555 48 94 3 0.0319148936170213 0.0625
GO:BP GO:0010817 regulation of hormone levels 0.0164735937294272 536 31 5 0.161290322580645 0.00932835820895522
GO:BP GO:0007548 sex differentiation 0.0164996783766228 275 17 3 0.176470588235294 0.0109090909090909
GO:BP GO:0070727 cellular macromolecule localization 0.0165613846965313 2024 78 18 0.230769230769231 0.00889328063241107
GO:BP GO:0072657 protein localization to membrane 0.0176314925850859 665 78 9 0.115384615384615 0.0135338345864662
GO:BP GO:0051651 maintenance of location in cell 0.0212534665623333 223 23 3 0.130434782608696 0.0134529147982063
GO:BP GO:2001233 regulation of apoptotic signaling pathway 0.0219023790492294 363 94 7 0.074468085106383 0.0192837465564738
GO:BP GO:0043687 post-translational protein modification 0.0220817382633095 362 30 4 0.133333333333333 0.0110497237569061
GO:BP GO:0080134 regulation of response to stress 0.0224898612589316 1443 94 16 0.170212765957447 0.0110880110880111
GO:BP GO:0006508 proteolysis 0.02368753636442 1836 62 14 0.225806451612903 0.00762527233115468
GO:BP GO:0042180 cellular ketone metabolic process 0.0242353662232607 271 41 4 0.0975609756097561 0.014760147601476
GO:BP GO:0019217 regulation of fatty acid metabolic process 0.0243712588840992 105 105 4 0.0380952380952381 0.0380952380952381
GO:BP GO:0006796 phosphate-containing compound metabolic process 0.025022865259687 3087 31 12 0.387096774193548 0.00388726919339164
GO:BP GO:0071827 plasma lipoprotein particle organization 0.0251097633914313 52 105 3 0.0285714285714286 0.0576923076923077
GO:BP GO:0019222 regulation of metabolic process 0.025126504428309 7148 9 8 0.888888888888889 0.00111919418019026
GO:BP GO:0006793 phosphorus metabolic process 0.0265624799490931 3114 31 12 0.387096774193548 0.00385356454720617
GO:BP GO:0006639 acylglycerol metabolic process 0.0278289782886173 141 82 4 0.0487804878048781 0.0283687943262411
GO:BP GO:0097190 apoptotic signaling pathway 0.0282430582118119 600 94 9 0.0957446808510638 0.015
GO:BP GO:0006638 neutral lipid metabolic process 0.0282430582118119 142 82 4 0.0487804878048781 0.028169014084507
GO:BP GO:0051179 localization 0.0282651993072447 6901 83 44 0.530120481927711 0.00637588755252862
GO:BP GO:0046903 secretion 0.0284337788554278 1501 77 14 0.181818181818182 0.00932711525649567
GO:BP GO:0071825 protein-lipid complex subunit organization 0.0293981028137923 56 105 3 0.0285714285714286 0.0535714285714286
GO:BP GO:0071417 cellular response to organonitrogen compound 0.0303026393268914 666 30 5 0.166666666666667 0.00750750750750751
GO:BP GO:0090114 COPII-coated vesicle budding 0.0303026393268914 72 83 3 0.036144578313253 0.0416666666666667
GO:BP GO:0044070 regulation of anion transport 0.0306643777755145 896 115 13 0.11304347826087 0.0145089285714286
GO:BP GO:1901575 organic substance catabolic process 0.0313764114498767 2267 64 16 0.25 0.0070577856197618
GO:BP GO:0032940 secretion by cell 0.0315769039285115 1364 77 13 0.168831168831169 0.00953079178885631
GO:BP GO:0002444 myeloid leukocyte mediated immunity 0.0318266259197366 551 105 9 0.0857142857142857 0.0163339382940109
GO:BP GO:0006887 exocytosis 0.0323523132687315 904 77 10 0.12987012987013 0.0110619469026549
GO:BP GO:0010876 lipid localization 0.0330012120301214 530 110 9 0.0818181818181818 0.0169811320754717
GO:BP GO:0002446 neutrophil mediated immunity 0.0337339906837744 497 77 7 0.0909090909090909 0.0140845070422535
GO:BP GO:0006950 response to stress 0.0338122711925415 4170 94 33 0.351063829787234 0.0079136690647482
GO:BP GO:0006511 ubiquitin-dependent protein catabolic process 0.0339903321109938 655 59 7 0.11864406779661 0.0106870229007634
GO:BP GO:0044248 cellular catabolic process 0.0343179858998382 2347 114 25 0.219298245614035 0.0106518960374947
GO:BP GO:0002274 myeloid leukocyte activation 0.0343603898407537 667 105 10 0.0952380952380952 0.0149925037481259
GO:BP GO:0010565 regulation of cellular ketone metabolic process 0.034885174337086 194 105 5 0.0476190476190476 0.0257731958762887
GO:BP GO:0019941 modification-dependent protein catabolic process 0.0350687381538155 662 59 7 0.11864406779661 0.0105740181268882
GO:BP GO:0006487 protein N-linked glycosylation 0.0355167156720805 76 86 3 0.0348837209302326 0.0394736842105263
GO:BP GO:0045055 regulated exocytosis 0.0358936225946271 785 105 11 0.104761904761905 0.0140127388535032
GO:BP GO:0106106 cold-induced thermogenesis 0.0358936225946271 144 90 4 0.0444444444444444 0.0277777777777778
GO:BP GO:0009894 regulation of catabolic process 0.0358936225946271 1033 115 14 0.121739130434783 0.0135527589545015
GO:BP GO:0120161 regulation of cold-induced thermogenesis 0.0358936225946271 144 90 4 0.0444444444444444 0.0277777777777778
GO:BP GO:0044265 cellular macromolecule catabolic process 0.036814719186537 1231 50 9 0.18 0.00731112916328188
GO:BP GO:0044237 cellular metabolic process 0.0369049803156088 10871 10 10 1 0.000919878576027964
GO:BP GO:0043632 modification-dependent macromolecule catabolic process 0.0369049803156088 673 59 7 0.11864406779661 0.0104011887072808
GO:BP GO:1901699 cellular response to nitrogen compound 0.0376913265170706 724 30 5 0.166666666666667 0.0069060773480663
GO:BP GO:0031329 regulation of cellular catabolic process 0.0377395571802672 866 110 12 0.109090909090909 0.0138568129330254
GO:BP GO:0009056 catabolic process 0.0378968437565 2744 115 28 0.243478260869565 0.0102040816326531
GO:BP GO:0030879 mammary gland development 0.0381232854279444 140 96 4 0.0416666666666667 0.0285714285714286
GO:BP GO:0031331 positive regulation of cellular catabolic process 0.0381232854279444 393 101 7 0.0693069306930693 0.0178117048346056
GO:BP GO:0140352 export from cell 0.0381232854279444 1418 77 13 0.168831168831169 0.00916784203102962
GO:BP GO:0032869 cellular response to insulin stimulus 0.0386208618669332 235 30 3 0.1 0.0127659574468085
GO:BP GO:0043271 negative regulation of ion transport 0.0390819781724812 349 115 7 0.0608695652173913 0.0200573065902579
GO:BP GO:0098657 import into cell 0.0391913547110014 235 92 5 0.0543478260869565 0.0212765957446809
GO:BP GO:0048608 reproductive structure development 0.0394713709485352 429 17 3 0.176470588235294 0.00699300699300699
GO:BP GO:0098656 anion transmembrane transport 0.0396160318085774 550 112 9 0.0803571428571429 0.0163636363636364
GO:BP GO:0061458 reproductive system development 0.0397849550030552 432 17 3 0.176470588235294 0.00694444444444444
GO:BP GO:1990845 adaptive thermogenesis 0.0406835648832013 155 90 4 0.0444444444444444 0.0258064516129032
GO:BP GO:0031667 response to nutrient levels 0.0415496121608369 482 30 4 0.133333333333333 0.00829875518672199
GO:BP GO:1905039 carboxylic acid transmembrane transport 0.0429225102745518 154 93 4 0.043010752688172 0.025974025974026
GO:BP GO:0045444 fat cell differentiation 0.0431174850596411 229 33 3 0.0909090909090909 0.0131004366812227
GO:BP GO:1903825 organic acid transmembrane transport 0.0435090892457652 155 93 4 0.043010752688172 0.0258064516129032
GO:BP GO:0048732 gland development 0.0438400703878577 436 96 7 0.0729166666666667 0.0160550458715596
GO:BP GO:2001242 regulation of intrinsic apoptotic signaling pathway 0.0442712414318655 167 87 4 0.0459770114942529 0.0239520958083832
GO:BP GO:0007584 response to nutrient 0.044285959768145 182 80 4 0.05 0.021978021978022
GO:BP GO:0019725 cellular homeostasis 0.0445209110554104 981 66 9 0.136363636363636 0.00917431192660551
GO:BP GO:0006869 lipid transport 0.0445209110554104 480 110 8 0.0727272727272727 0.0166666666666667
GO:BP GO:0009314 response to radiation 0.0464687823200277 461 33 4 0.121212121212121 0.00867678958785249
GO:BP GO:0098739 import across plasma membrane 0.0467635084983465 163 92 4 0.0434782608695652 0.0245398773006135
GO:BP GO:0009991 response to extracellular stimulus 0.0471018496679311 512 30 4 0.133333333333333 0.0078125
GO:BP GO:0062013 positive regulation of small molecule metabolic process 0.0485707421547686 145 105 4 0.0380952380952381 0.0275862068965517
GO:CC GO:0005783 endoplasmic reticulum 8.66497605714245e-38 1982 110 69 0.627272727272727 0.0348133198789102
GO:CC GO:0098827 endoplasmic reticulum subcompartment 3.77035268919985e-36 1122 110 55 0.5 0.0490196078431373
GO:CC GO:0005789 endoplasmic reticulum membrane 3.77035268919985e-36 1117 110 55 0.5 0.0492390331244405
GO:CC GO:0042175 nuclear outer membrane-endoplasmic reticulum membrane network 6.26836740097197e-36 1139 110 55 0.5 0.04828797190518
GO:CC GO:0031984 organelle subcompartment 3.95648867240659e-28 1773 110 57 0.518181818181818 0.0321489001692047
GO:CC GO:0012505 endomembrane system 4.3840200372155e-22 4640 110 77 0.7 0.0165948275862069
GO:CC GO:0031090 organelle membrane 5.08762828554132e-16 3612 112 62 0.553571428571429 0.0171650055370986
GO:CC GO:0005737 cytoplasm 3.13347209341051e-14 11911 90 88 0.977777777777778 0.0073881286206028
GO:CC GO:0140534 endoplasmic reticulum protein-containing complex 3.13347209341051e-14 128 110 15 0.136363636363636 0.1171875
GO:CC GO:0043231 intracellular membrane-bounded organelle 4.37118592081751e-13 11296 116 106 0.913793103448276 0.00938385269121813
GO:CC GO:0043227 membrane-bounded organelle 2.96836698042408e-12 12858 116 111 0.956896551724138 0.00863275781614559
GO:CC GO:0043229 intracellular organelle 1.18037905009492e-11 12491 116 109 0.939655172413793 0.00872628292370507
GO:CC GO:0030176 integral component of endoplasmic reticulum membrane 1.84607212872167e-10 158 110 13 0.118181818181818 0.0822784810126582
GO:CC GO:0042470 melanosome 2.63274389053571e-10 105 76 10 0.131578947368421 0.0952380952380952
GO:CC GO:0048770 pigment granule 2.63274389053571e-10 105 76 10 0.131578947368421 0.0952380952380952
GO:CC GO:0031227 intrinsic component of endoplasmic reticulum membrane 2.8133133033961e-10 166 110 13 0.118181818181818 0.0783132530120482
GO:CC GO:0034663 endoplasmic reticulum chaperone complex 1.39063361939869e-09 9 70 5 0.0714285714285714 0.555555555555556
GO:CC GO:0005622 intracellular anatomical structure 2.38149616644856e-09 14790 105 104 0.990476190476191 0.00703177822853279
GO:CC GO:0043226 organelle 8.76744330199257e-09 14008 116 111 0.956896551724138 0.00792404340376928
GO:CC GO:0005793 endoplasmic reticulum-Golgi intermediate compartment 3.8387548014509e-08 131 103 10 0.0970873786407767 0.0763358778625954
GO:CC GO:0031301 integral component of organelle membrane 1.12867597947543e-07 382 112 15 0.133928571428571 0.0392670157068063
GO:CC GO:0005788 endoplasmic reticulum lumen 1.7241639849435e-07 307 103 13 0.12621359223301 0.0423452768729642
GO:CC GO:0031300 intrinsic component of organelle membrane 2.91781500106413e-07 413 112 15 0.133928571428571 0.036319612590799
GO:CC GO:0097708 intracellular vesicle 3.66962465691311e-07 2428 77 29 0.376623376623377 0.0119439868204283
GO:CC GO:0031410 cytoplasmic vesicle 3.66962465691311e-07 2424 77 29 0.376623376623377 0.011963696369637
GO:CC GO:0016021 integral component of membrane 7.53393444612552e-06 5711 115 60 0.521739130434783 0.0105060409735598
GO:CC GO:0031224 intrinsic component of membrane 7.77331158515855e-06 5868 115 61 0.530434782608696 0.0103953646898432
GO:CC GO:0030134 COPII-coated ER to Golgi transport vesicle 1.04848866981647e-05 90 110 7 0.0636363636363636 0.0777777777777778
GO:CC GO:0048500 signal recognition particle 1.41625106651816e-05 6 78 3 0.0384615384615385 0.5
GO:CC GO:0005786 signal recognition particle, endoplasmic reticulum targeting 1.41625106651816e-05 6 78 3 0.0384615384615385 0.5
GO:CC GO:0016020 membrane 4.01590467194405e-05 9838 84 64 0.761904761904762 0.00650538727383615
GO:CC GO:0005791 rough endoplasmic reticulum 6.47446290628965e-05 86 58 5 0.0862068965517241 0.0581395348837209
GO:CC GO:0005790 smooth endoplasmic reticulum 7.04598714080658e-05 34 70 4 0.0571428571428571 0.117647058823529
GO:CC GO:0098588 bounding membrane of organelle 0.000104080594539478 2158 83 24 0.289156626506024 0.0111214087117702
GO:CC GO:0033116 endoplasmic reticulum-Golgi intermediate compartment membrane 0.000165398820320425 74 83 5 0.0602409638554217 0.0675675675675676
GO:CC GO:0005777 peroxisome 0.000244817712385573 141 80 6 0.075 0.0425531914893617
GO:CC GO:0042579 microbody 0.000244817712385573 141 80 6 0.075 0.0425531914893617
GO:CC GO:0044322 endoplasmic reticulum quality control compartment 0.00063508881528832 27 59 3 0.0508474576271186 0.111111111111111
GO:CC GO:0030867 rough endoplasmic reticulum membrane 0.000732173678167543 29 58 3 0.0517241379310345 0.103448275862069
GO:CC GO:0070062 extracellular exosome 0.000825922184459993 2176 77 21 0.272727272727273 0.00965073529411765
GO:CC GO:0031982 vesicle 0.000974098456853139 4055 77 31 0.402597402597403 0.00764488286066584
GO:CC GO:0005811 lipid droplet 0.00109442193315019 95 101 5 0.0495049504950495 0.0526315789473684
GO:CC GO:1903561 extracellular vesicle 0.00131805509156729 2261 77 21 0.272727272727273 0.00928792569659443
GO:CC GO:0043230 extracellular organelle 0.00131805509156729 2263 77 21 0.272727272727273 0.00927971718957137
GO:CC GO:0005766 primary lysosome 0.00880032040509022 154 101 5 0.0495049504950495 0.0324675324675325
GO:CC GO:0042582 azurophil granule 0.00880032040509022 154 101 5 0.0495049504950495 0.0324675324675325
GO:CC GO:0005925 focal adhesion 0.00999427197463598 420 78 7 0.0897435897435897 0.0166666666666667
GO:CC GO:0030135 coated vesicle 0.00999427197463598 295 110 7 0.0636363636363636 0.023728813559322
GO:CC GO:0000139 Golgi membrane 0.00999427197463598 771 110 12 0.109090909090909 0.0155642023346304
GO:CC GO:0031968 organelle outer membrane 0.0104208732973558 227 107 6 0.0560747663551402 0.026431718061674
GO:CC GO:0030055 cell-substrate junction 0.0104920794775428 427 78 7 0.0897435897435897 0.0163934426229508
GO:CC GO:0019867 outer membrane 0.0105160960843693 229 107 6 0.0560747663551402 0.0262008733624454
GO:CC GO:0005778 peroxisomal membrane 0.0129258183911039 64 80 3 0.0375 0.046875
GO:CC GO:0031903 microbody membrane 0.0129258183911039 64 80 3 0.0375 0.046875
GO:CC GO:0005635 nuclear envelope 0.0153120440563606 467 99 8 0.0808080808080808 0.0171306209850107
GO:CC GO:0005615 extracellular space 0.0153120440563606 3594 77 25 0.324675324675325 0.00695603784084585
GO:CC GO:1904813 ficolin-1-rich granule lumen 0.019408026070134 124 101 4 0.0396039603960396 0.032258064516129
GO:CC GO:0012507 ER to Golgi transport vesicle membrane 0.0194116111150797 57 110 3 0.0272727272727273 0.0526315789473684
GO:CC GO:0000323 lytic vacuole 0.0198506636989335 712 101 10 0.099009900990099 0.0140449438202247
GO:CC GO:0005764 lysosome 0.0198506636989335 712 101 10 0.099009900990099 0.0140449438202247
GO:CC GO:0098791 Golgi apparatus subcompartment 0.0217968399799574 885 110 12 0.109090909090909 0.0135593220338983
GO:CC GO:0005794 Golgi apparatus 0.0228650394445965 1623 110 18 0.163636363636364 0.011090573012939
GO:CC GO:0005829 cytosol 0.0231078666158476 5303 29 15 0.517241379310345 0.0028285875919291
GO:CC GO:0005741 mitochondrial outer membrane 0.0231078666158476 202 107 5 0.0467289719626168 0.0247524752475248
GO:CC GO:0009986 cell surface 0.0250939381112791 899 36 6 0.166666666666667 0.00667408231368187
GO:CC GO:0070161 anchoring junction 0.0279026879481927 836 78 9 0.115384615384615 0.0107655502392345
GO:CC GO:0048471 perinuclear region of cytoplasm 0.0324792999790835 735 107 10 0.0934579439252336 0.0136054421768707
GO:CC GO:0030133 transport vesicle 0.0345571315421523 414 83 6 0.072289156626506 0.0144927536231884
GO:CC GO:0005773 vacuole 0.0381754871106455 810 101 10 0.099009900990099 0.0123456790123457
GO:CC GO:0035578 azurophil granule lumen 0.0428006835661817 91 101 3 0.0297029702970297 0.032967032967033
GO:MF GO:0016491 oxidoreductase activity 4.63189162822321e-09 771 73 20 0.273972602739726 0.0259403372243839
GO:MF GO:0016616 oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor 2.72219668704658e-06 125 64 8 0.125 0.064
GO:MF GO:0016614 oxidoreductase activity, acting on CH-OH group of donors 3.73453067935502e-06 137 64 8 0.125 0.0583941605839416
GO:MF GO:0003824 catalytic activity 1.04130554938421e-05 5896 32 25 0.78125 0.00424016282225237
GO:MF GO:0016860 intramolecular oxidoreductase activity 3.04682990365625e-05 53 22 4 0.181818181818182 0.0754716981132075
GO:MF GO:0015037 peptide disulfide oxidoreductase activity 3.04682990365625e-05 13 87 4 0.0459770114942529 0.307692307692308
GO:MF GO:0004312 fatty acid synthase activity 3.04682990365625e-05 11 109 4 0.036697247706422 0.363636363636364
GO:MF GO:0005515 protein binding 3.31722792727688e-05 14767 114 109 0.956140350877193 0.00738132322069479
GO:MF GO:0016717 oxidoreductase activity, acting on paired donors, with oxidation of a pair of donors resulting in the reduction of molecular oxygen to two molecules of water 3.31722792727688e-05 5 73 3 0.0410958904109589 0.6
GO:MF GO:0016853 isomerase activity 3.43741849455302e-05 169 35 6 0.171428571428571 0.0355029585798817
GO:MF GO:0016705 oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen 5.91648747944471e-05 167 10 4 0.4 0.0239520958083832
GO:MF GO:0008312 7S RNA binding 0.000105826760800454 7 78 3 0.0384615384615385 0.428571428571429
GO:MF GO:0009922 fatty acid elongase activity 0.000205113155555629 7 109 3 0.0275229357798165 0.428571428571429
GO:MF GO:0102337 3-oxo-cerotoyl-CoA synthase activity 0.000205113155555629 7 109 3 0.0275229357798165 0.428571428571429
GO:MF GO:0102336 3-oxo-arachidoyl-CoA synthase activity 0.000205113155555629 7 109 3 0.0275229357798165 0.428571428571429
GO:MF GO:0102756 very-long-chain 3-ketoacyl-CoA synthase activity 0.000205113155555629 7 109 3 0.0275229357798165 0.428571428571429
GO:MF GO:0102338 3-oxo-lignoceronyl-CoA synthase activity 0.000205113155555629 7 109 3 0.0275229357798165 0.428571428571429
GO:MF GO:0050661 NADP binding 0.000212424368790693 52 97 5 0.0515463917525773 0.0961538461538462
GO:MF GO:0016628 oxidoreductase activity, acting on the CH-CH group of donors, NAD or NADP as acceptor 0.000264822287912467 27 29 3 0.103448275862069 0.111111111111111
GO:MF GO:0016864 intramolecular oxidoreductase activity, transposing S-S bonds 0.000737209756162592 19 61 3 0.0491803278688525 0.157894736842105
GO:MF GO:0003756 protein disulfide isomerase activity 0.000737209756162592 19 61 3 0.0491803278688525 0.157894736842105
GO:MF GO:0015036 disulfide oxidoreductase activity 0.000888522802501258 41 87 4 0.0459770114942529 0.0975609756097561
GO:MF GO:0051087 chaperone binding 0.000910746890333755 103 70 5 0.0714285714285714 0.0485436893203883
GO:MF GO:0051787 misfolded protein binding 0.00109507077753958 28 50 3 0.06 0.107142857142857
GO:MF GO:0033764 steroid dehydrogenase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor 0.00170979153195466 30 56 3 0.0535714285714286 0.1
GO:MF GO:0043022 ribosome binding 0.0017624215679502 59 78 4 0.0512820512820513 0.0677966101694915
GO:MF GO:0003723 RNA binding 0.00194340651339769 1943 116 26 0.224137931034483 0.013381369016984
GO:MF GO:0016627 oxidoreductase activity, acting on the CH-CH group of donors 0.00212404160997882 65 29 3 0.103448275862069 0.0461538461538462
GO:MF GO:0016229 steroid dehydrogenase activity 0.00233757788271008 35 56 3 0.0535714285714286 0.0857142857142857
GO:MF GO:0016667 oxidoreductase activity, acting on a sulfur group of donors 0.00247431481393686 60 87 4 0.0459770114942529 0.0666666666666667
GO:MF GO:0050750 low-density lipoprotein particle receptor binding 0.00333714956599884 23 103 3 0.029126213592233 0.130434782608696
GO:MF GO:0036094 small molecule binding 0.00333714956599884 2506 101 27 0.267326732673267 0.0107741420590583
GO:MF GO:0005488 binding 0.00406384804160912 17074 116 115 0.991379310344828 0.00673538713833899
GO:MF GO:0070325 lipoprotein particle receptor binding 0.00468470205843999 28 103 3 0.029126213592233 0.107142857142857
GO:MF GO:0031072 heat shock protein binding 0.00506759577992353 127 55 4 0.0727272727272727 0.031496062992126
GO:MF GO:0016746 transferase activity, transferring acyl groups 0.00712568885624824 261 109 7 0.0642201834862385 0.0268199233716475
GO:MF GO:0051082 unfolded protein binding 0.00712568885624824 112 70 4 0.0571428571428571 0.0357142857142857
GO:MF GO:0000166 nucleotide binding 0.00795967717915863 2171 101 23 0.227722772277228 0.0105941962229387
GO:MF GO:1901265 nucleoside phosphate binding 0.00795967717915863 2172 101 23 0.227722772277228 0.0105893186003683
GO:MF GO:0045296 cadherin binding 0.0109953645691523 333 74 6 0.0810810810810811 0.018018018018018
GO:MF GO:0016874 ligase activity 0.0111406640156646 177 95 5 0.0526315789473684 0.0282485875706215
GO:MF GO:0043021 ribonucleoprotein complex binding 0.0132175304190666 137 78 4 0.0512820512820513 0.0291970802919708
GO:MF GO:0097159 organic cyclic compound binding 0.0134389193411046 6309 116 54 0.46551724137931 0.00855920114122682
GO:MF GO:0003713 transcription coactivator activity 0.014572447995271 280 98 6 0.0612244897959184 0.0214285714285714
GO:MF GO:0030554 adenyl nucleotide binding 0.0172660922286111 1578 101 17 0.168316831683168 0.0107731305449937
GO:MF GO:0004860 protein kinase inhibitor activity 0.018631550979554 70 94 3 0.0319148936170213 0.0428571428571429
GO:MF GO:0050839 cell adhesion molecule binding 0.0197196809648319 546 74 7 0.0945945945945946 0.0128205128205128
GO:MF GO:0019210 kinase inhibitor activity 0.0203797993815398 74 94 3 0.0319148936170213 0.0405405405405405
GO:MF GO:0046872 metal ion binding 0.0203797993815398 4260 9 6 0.666666666666667 0.00140845070422535
GO:MF GO:1901363 heterocyclic compound binding 0.0207748353713886 6228 116 52 0.448275862068966 0.00834938985228003
GO:MF GO:0043167 ion binding 0.0217548009484861 6057 9 7 0.777777777777778 0.00115568763414231
GO:MF GO:0043169 cation binding 0.0217548009484861 4351 9 6 0.666666666666667 0.00137899333486555
GO:MF GO:0032559 adenyl ribonucleotide binding 0.0286478117256377 1565 101 16 0.158415841584158 0.010223642172524
GO:MF GO:0016747 transferase activity, transferring acyl groups other than amino-acyl groups 0.0317137590331627 230 109 5 0.0458715596330275 0.0217391304347826
GO:MF GO:0003712 transcription coregulator activity 0.0328149346455502 506 113 8 0.0707964601769911 0.0158102766798419
GO:MF GO:0097367 carbohydrate derivative binding 0.0335319643386326 2285 103 21 0.203883495145631 0.00919037199124726
GO:MF GO:0046914 transition metal ion binding 0.0352440594783971 1111 9 3 0.333333333333333 0.0027002700270027
GO:MF GO:0005524 ATP binding 0.0380789678231685 1501 101 15 0.148514851485149 0.00999333777481679
GO:MF GO:0046906 tetrapyrrole binding 0.0381383348827504 154 115 4 0.0347826086956522 0.025974025974026
GO:MF GO:0004197 cysteine-type endopeptidase activity 0.043125079877722 121 85 3 0.0352941176470588 0.0247933884297521
HP HP:0003107 Abnormal circulating cholesterol concentration 0.00855506561561889 100 32 7 0.21875 0.07
HP HP:0003146 Hypocholesterolemia 0.00946536654197837 13 16 3 0.1875 0.230769230769231
HP HP:0200044 Porokeratosis 0.0463733425352023 7 67 3 0.0447761194029851 0.428571428571429
HPA HPA:0350473 pancreas; exocrine glandular cells[High] 0.00200891955144081 1879 76 30 0.394736842105263 0.0159659393294305
HPA HPA:0180053 epididymis; glandular cells[High] 0.00329446913501476 1779 76 28 0.368421052631579 0.0157391793142215
HPA HPA:0290402 liver; hepatocytes[≥Medium] 0.00357121982473588 3640 47 30 0.638297872340426 0.00824175824175824
HPA HPA:0380523 placenta; trophoblastic cells[High] 0.00440297919269835 1998 110 38 0.345454545454545 0.019019019019019
HPA HPA:0550053 stomach 2; glandular cells[High] 0.00440297919269835 2350 63 28 0.444444444444444 0.0119148936170213
HPA HPA:0570733 testis; Leydig cells[High] 0.00501651932061961 1718 17 10 0.588235294117647 0.00582072176949942
HPA HPA:0430053 seminal vesicle; glandular cells[High] 0.00661364672385197 1410 73 22 0.301369863013699 0.0156028368794326
HPA HPA:0290401 liver; hepatocytes[≥Low] 0.00669157830272973 5611 78 57 0.730769230769231 0.0101586170023169
HPA HPA:0570732 testis; Leydig cells[≥Medium] 0.0132384372654055 5295 116 76 0.655172413793103 0.0143531633616619
HPA HPA:0180052 epididymis; glandular cells[≥Medium] 0.0137540916633163 5560 69 50 0.72463768115942 0.00899280575539568
HPA HPA:0290000 liver 0.0137540916633163 6158 64 50 0.78125 0.00811951932445599
HPA HPA:0150053 duodenum; glandular cells[High] 0.0137540916633163 2767 63 29 0.46031746031746 0.0104806649801229
HPA HPA:0540053 stomach 1; glandular cells[High] 0.014774981247511 2365 63 26 0.412698412698413 0.0109936575052854
HPA HPA:0430051 seminal vesicle; glandular cells[≥Low] 0.0443400336285422 6672 76 59 0.776315789473684 0.00884292565947242
HPA HPA:0020052 adrenal gland; glandular cells[≥Medium] 0.0443400336285422 5867 65 47 0.723076923076923 0.0080109084711096
HPA HPA:0100201 cerebral cortex; endothelial cells[≥Low] 0.0443400336285422 4556 74 44 0.594594594594595 0.009657594381036
HPA HPA:0150052 duodenum; glandular cells[≥Medium] 0.0443400336285422 6480 76 58 0.763157894736842 0.00895061728395062
HPA HPA:0170053 endometrium 2; glandular cells[High] 0.0443400336285422 1282 23 8 0.347826086956522 0.0062402496099844
HPA HPA:0190221 esophagus; squamous epithelial cells[≥Low] 0.0443400336285422 6524 69 53 0.768115942028985 0.00812385039852851
HPA HPA:0190222 esophagus; squamous epithelial cells[≥Medium] 0.0443400336285422 4937 75 47 0.626666666666667 0.00951995138748228
HPA HPA:0210051 fallopian tube; glandular cells[≥Low] 0.0443400336285422 6089 68 50 0.735294117647059 0.00821152898669732
HPA HPA:0350472 pancreas; exocrine glandular cells[≥Medium] 0.0443400336285422 5157 76 49 0.644736842105263 0.00950164824510374
HPA HPA:0390000 prostate 0.0443400336285422 6528 78 59 0.756410256410256 0.00903799019607843
HPA HPA:0380522 placenta; trophoblastic cells[≥Medium] 0.0443400336285422 5074 78 49 0.628205128205128 0.0096570752857706
HPA HPA:0020051 adrenal gland; glandular cells[≥Low] 0.0443400336285422 7265 78 64 0.82051282051282 0.0088093599449415
HPA HPA:0390051 prostate; glandular cells[≥Low] 0.0443400336285422 6528 78 59 0.756410256410256 0.00903799019607843
HPA HPA:0390053 prostate; glandular cells[High] 0.0443400336285422 1284 77 18 0.233766233766234 0.014018691588785
HPA HPA:0430000 seminal vesicle 0.0443400336285422 6672 76 59 0.776315789473684 0.00884292565947242
HPA HPA:0430052 seminal vesicle; glandular cells[≥Medium] 0.0443400336285422 5096 76 48 0.631578947368421 0.00941915227629513
HPA HPA:0480052 small intestine; glandular cells[≥Medium] 0.0443400336285422 6461 78 59 0.756410256410256 0.00913171335706547
HPA HPA:0480053 small intestine; glandular cells[High] 0.0443400336285422 2723 63 26 0.412698412698413 0.00954829232464194
HPA HPA:0540052 stomach 1; glandular cells[≥Medium] 0.0443400336285422 6201 78 57 0.730769230769231 0.00919206579583938
HPA HPA:0380512 placenta; decidual cells[≥Medium] 0.0443400336285422 3463 107 48 0.448598130841121 0.0138608143228415
HPA HPA:0020000 adrenal gland 0.0443400336285422 7271 78 64 0.82051282051282 0.00880209049649292
HPA HPA:0190000 esophagus 0.0443400336285422 6524 69 53 0.768115942028985 0.00812385039852851
HPA HPA:0050052 breast; glandular cells[≥Medium] 0.044679120874203 4971 76 47 0.618421052631579 0.00945483806075236
HPA HPA:0540000 stomach 1 0.044679120874203 7493 78 65 0.833333333333333 0.00867476311223809
HPA HPA:0540051 stomach 1; glandular cells[≥Low] 0.044679120874203 7493 78 65 0.833333333333333 0.00867476311223809
HPA HPA:0160052 endometrium 1; glandular cells[≥Medium] 0.0484880809000701 5014 74 46 0.621621621621622 0.00917431192660551
HPA HPA:0550052 stomach 2; glandular cells[≥Medium] 0.0484880809000701 6134 78 56 0.717948717948718 0.0091294424519074
KEGG KEGG:00100 Steroid biosynthesis 5.49816411252677e-16 20 115 12 0.104347826086957 0.6
KEGG KEGG:04141 Protein processing in endoplasmic reticulum 5.47708260819314e-11 170 71 16 0.225352112676056 0.0941176470588235
KEGG KEGG:00900 Terpenoid backbone biosynthesis 2.1673773350321e-09 22 27 6 0.222222222222222 0.272727272727273
KEGG KEGG:01212 Fatty acid metabolism 5.45482287229849e-09 57 109 11 0.100917431192661 0.192982456140351
KEGG KEGG:03060 Protein export 1.38746975836279e-06 23 78 6 0.0769230769230769 0.260869565217391
KEGG KEGG:01040 Biosynthesis of unsaturated fatty acids 2.41572801190264e-05 27 109 6 0.055045871559633 0.222222222222222
KEGG KEGG:01100 Metabolic pathways 3.42727545520495e-05 1490 32 18 0.5625 0.0120805369127517
KEGG KEGG:00061 Fatty acid biosynthesis 0.000641178832425681 18 93 4 0.043010752688172 0.222222222222222
KEGG KEGG:00062 Fatty acid elongation 0.00498674253688015 27 109 4 0.036697247706422 0.148148148148148
MIRNA MIRNA:hsa-miR-192-5p hsa-miR-192-5p 0.00151032823634812 989 52 15 0.288461538461538 0.0151668351870576
MIRNA MIRNA:hsa-miR-92a-3p hsa-miR-92a-3p 0.00205886534798817 1404 23 11 0.478260869565217 0.00783475783475784
MIRNA MIRNA:hsa-miR-4638-3p hsa-miR-4638-3p 0.00791409314363061 47 25 3 0.12 0.0638297872340425
MIRNA MIRNA:hsa-miR-6891-5p hsa-miR-6891-5p 0.00791409314363061 137 74 6 0.0810810810810811 0.0437956204379562
MIRNA MIRNA:hsa-miR-3919 hsa-miR-3919 0.00791409314363061 160 115 8 0.0695652173913043 0.05
MIRNA MIRNA:hsa-miR-34a-5p hsa-miR-34a-5p 0.00791409314363061 728 83 14 0.168674698795181 0.0192307692307692
MIRNA MIRNA:hsa-miR-335-5p hsa-miR-335-5p 0.00791409314363061 2571 35 17 0.485714285714286 0.00661221314663555
MIRNA MIRNA:hsa-miR-324-3p hsa-miR-324-3p 0.00791409314363061 336 108 11 0.101851851851852 0.0327380952380952
MIRNA MIRNA:hsa-miR-484 hsa-miR-484 0.00791409314363061 890 77 15 0.194805194805195 0.0168539325842697
MIRNA MIRNA:hsa-miR-215-5p hsa-miR-215-5p 0.00791409314363061 753 44 10 0.227272727272727 0.0132802124833997
MIRNA MIRNA:hsa-miR-4658 hsa-miR-4658 0.00791409314363061 63 17 3 0.176470588235294 0.0476190476190476
MIRNA MIRNA:hsa-miR-210-3p hsa-miR-210-3p 0.00791409314363061 123 10 3 0.3 0.024390243902439
MIRNA MIRNA:hsa-miR-6790-5p hsa-miR-6790-5p 0.00791409314363061 64 17 3 0.176470588235294 0.046875
MIRNA MIRNA:hsa-let-7e-5p hsa-let-7e-5p 0.00791409314363061 608 6 4 0.666666666666667 0.00657894736842105
MIRNA MIRNA:hsa-let-7b-5p hsa-let-7b-5p 0.0103003024337238 1212 112 22 0.196428571428571 0.0181518151815182
MIRNA MIRNA:hsa-miR-583 hsa-miR-583 0.014530278789161 155 108 7 0.0648148148148148 0.0451612903225806
MIRNA MIRNA:hsa-miR-7705 hsa-miR-7705 0.0166536489780566 50 32 3 0.09375 0.06
MIRNA MIRNA:hsa-miR-22-3p hsa-miR-22-3p 0.0253488198588351 163 13 3 0.230769230769231 0.0184049079754601
MIRNA MIRNA:hsa-miR-455-3p hsa-miR-455-3p 0.0267641800692112 782 116 16 0.137931034482759 0.020460358056266
MIRNA MIRNA:hsa-miR-615-3p hsa-miR-615-3p 0.0269712208086025 891 113 17 0.150442477876106 0.0190796857463524
MIRNA MIRNA:hsa-miR-1260b hsa-miR-1260b 0.0269712208086025 270 20 4 0.2 0.0148148148148148
MIRNA MIRNA:hsa-miR-1245b-3p hsa-miR-1245b-3p 0.0286645005646969 78 69 4 0.0579710144927536 0.0512820512820513
MIRNA MIRNA:hsa-miR-3173-3p hsa-miR-3173-3p 0.0319337864164459 134 74 5 0.0675675675675676 0.0373134328358209
MIRNA MIRNA:hsa-miR-23c hsa-miR-23c 0.0336257621554164 131 45 4 0.0888888888888889 0.0305343511450382
MIRNA MIRNA:hsa-miR-130a-5p hsa-miR-130a-5p 0.0336257621554164 130 45 4 0.0888888888888889 0.0307692307692308
MIRNA MIRNA:hsa-miR-93-3p hsa-miR-93-3p 0.0336257621554164 268 80 7 0.0875 0.0261194029850746
MIRNA MIRNA:hsa-miR-1255b-2-3p hsa-miR-1255b-2-3p 0.0342977182269677 56 107 4 0.0373831775700935 0.0714285714285714
MIRNA MIRNA:hsa-miR-3692-3p hsa-miR-3692-3p 0.0342977182269677 127 21 3 0.142857142857143 0.0236220472440945
MIRNA MIRNA:hsa-miR-6882-5p hsa-miR-6882-5p 0.0352280994734856 67 41 3 0.0731707317073171 0.0447761194029851
MIRNA MIRNA:hsa-miR-191-5p hsa-miR-191-5p 0.0352280994734856 78 80 4 0.05 0.0512820512820513
MIRNA MIRNA:hsa-miR-1267 hsa-miR-1267 0.0358709002119176 154 107 6 0.0560747663551402 0.038961038961039
MIRNA MIRNA:hsa-miR-378d hsa-miR-378d 0.036287827707804 34 93 3 0.032258064516129 0.0882352941176471
MIRNA MIRNA:hsa-miR-498 hsa-miR-498 0.036287827707804 316 22 4 0.181818181818182 0.0126582278481013
MIRNA MIRNA:hsa-miR-378e hsa-miR-378e 0.036287827707804 34 93 3 0.032258064516129 0.0882352941176471
MIRNA MIRNA:hsa-miR-378f hsa-miR-378f 0.036287827707804 34 93 3 0.032258064516129 0.0882352941176471
MIRNA MIRNA:hsa-miR-652-3p hsa-miR-652-3p 0.036287827707804 162 109 6 0.055045871559633 0.037037037037037
MIRNA MIRNA:hsa-miR-378h hsa-miR-378h 0.036287827707804 34 93 3 0.032258064516129 0.0882352941176471
MIRNA MIRNA:hsa-miR-6511b-5p hsa-miR-6511b-5p 0.036287827707804 105 62 4 0.0645161290322581 0.0380952380952381
MIRNA MIRNA:hsa-miR-19b-3p hsa-miR-19b-3p 0.036287827707804 712 5 3 0.6 0.00421348314606742
MIRNA MIRNA:hsa-miR-124-3p hsa-miR-124-3p 0.036287827707804 1442 51 13 0.254901960784314 0.00901525658807212
MIRNA MIRNA:hsa-miR-145-3p hsa-miR-145-3p 0.036287827707804 59 116 4 0.0344827586206897 0.0677966101694915
MIRNA MIRNA:hsa-miR-6077 hsa-miR-6077 0.036287827707804 278 61 6 0.0983606557377049 0.0215827338129496
MIRNA MIRNA:hsa-miR-378i hsa-miR-378i 0.036287827707804 34 93 3 0.032258064516129 0.0882352941176471
MIRNA MIRNA:hsa-miR-4694-3p hsa-miR-4694-3p 0.036287827707804 120 57 4 0.0701754385964912 0.0333333333333333
MIRNA MIRNA:hsa-miR-6811-5p hsa-miR-6811-5p 0.036287827707804 104 62 4 0.0645161290322581 0.0384615384615385
MIRNA MIRNA:hsa-miR-4262 hsa-miR-4262 0.036287827707804 134 23 3 0.130434782608696 0.0223880597014925
MIRNA MIRNA:hsa-miR-193b-3p hsa-miR-193b-3p 0.036287827707804 847 76 12 0.157894736842105 0.0141676505312869
MIRNA MIRNA:hsa-miR-6516-3p hsa-miR-6516-3p 0.0381186796192463 85 38 3 0.0789473684210526 0.0352941176470588
MIRNA MIRNA:hsa-miR-378b hsa-miR-378b 0.0381874769281614 35 93 3 0.032258064516129 0.0857142857142857
MIRNA MIRNA:hsa-miR-937-5p hsa-miR-937-5p 0.0408005656268161 83 91 4 0.043956043956044 0.0481927710843374
MIRNA MIRNA:hsa-miR-875-3p hsa-miR-875-3p 0.0408005656268161 109 116 5 0.0431034482758621 0.0458715596330275
MIRNA MIRNA:hsa-miR-324-5p hsa-miR-324-5p 0.0408005656268161 297 86 7 0.0813953488372093 0.0235690235690236
MIRNA MIRNA:hsa-miR-342-3p hsa-miR-342-3p 0.041959499711653 300 110 8 0.0727272727272727 0.0266666666666667
MIRNA MIRNA:hsa-miR-378c hsa-miR-378c 0.0436387963460912 39 93 3 0.032258064516129 0.0769230769230769
MIRNA MIRNA:hsa-miR-584-3p hsa-miR-584-3p 0.0438447528274607 56 65 3 0.0461538461538462 0.0535714285714286
MIRNA MIRNA:hsa-miR-766-3p hsa-miR-766-3p 0.0470854923377255 604 70 9 0.128571428571429 0.0149006622516556
REAC REAC:R-HSA-191273 Cholesterol biosynthesis 4.95841120156759e-29 24 115 18 0.156521739130435 0.75
REAC REAC:R-HSA-8957322 Metabolism of steroids 5.89338465049056e-23 148 41 19 0.463414634146341 0.128378378378378
REAC REAC:R-HSA-2426168 Activation of gene expression by SREBF (SREBP) 1.00665928841844e-21 40 115 17 0.147826086956522 0.425
REAC REAC:R-HSA-1655829 Regulation of cholesterol biosynthesis by SREBP (SREBF) 4.61326653628286e-21 53 115 18 0.156521739130435 0.339622641509434
REAC REAC:R-HSA-556833 Metabolism of lipids 5.18652725298337e-15 730 115 38 0.330434782608696 0.0520547945205479
REAC REAC:R-HSA-75105 Fatty acyl-CoA biosynthesis 1.37451148106101e-10 37 109 10 0.0917431192660551 0.27027027027027
REAC REAC:R-HSA-6807062 Cholesterol biosynthesis via lathosterol 2.84805843208813e-09 4 32 4 0.125 1
REAC REAC:R-HSA-6807047 Cholesterol biosynthesis via desmosterol 2.84805843208813e-09 4 32 4 0.125 1
REAC REAC:R-HSA-75876 Synthesis of very long-chain fatty acyl-CoAs 4.24998178246756e-06 24 109 6 0.055045871559633 0.25
REAC REAC:R-HSA-1430728 Metabolism 4.24998178246756e-06 2070 32 20 0.625 0.00966183574879227
REAC REAC:R-HSA-2046105 Linoleic acid (LA) metabolism 2.17248659510683e-05 8 109 4 0.036697247706422 0.5
REAC REAC:R-HSA-381119 Unfolded Protein Response (UPR) 2.9002885653278e-05 91 91 8 0.0879120879120879 0.0879120879120879
REAC REAC:R-HSA-1799339 SRP-dependent cotranslational protein targeting to membrane 3.97125019867179e-05 113 78 8 0.102564102564103 0.0707964601769911
REAC REAC:R-HSA-8978868 Fatty acid metabolism 3.97125019867179e-05 173 109 11 0.100917431192661 0.0635838150289017
REAC REAC:R-HSA-2046104 alpha-linolenic (omega3) and linoleic (omega6) acid metabolism 0.000102295202028317 12 109 4 0.036697247706422 0.333333333333333
REAC REAC:R-HSA-2046106 alpha-linolenic acid (ALA) metabolism 0.000102295202028317 12 109 4 0.036697247706422 0.333333333333333
REAC REAC:R-HSA-381070 IRE1alpha activates chaperones 0.000325409212288055 49 70 5 0.0714285714285714 0.102040816326531
REAC REAC:R-HSA-163765 ChREBP activates metabolic gene expression 0.000410583281799873 7 93 3 0.032258064516129 0.428571428571429
REAC REAC:R-HSA-8957275 Post-translational protein phosphorylation 0.0024783477044781 107 50 5 0.1 0.0467289719626168
REAC REAC:R-HSA-400206 Regulation of lipid metabolism by PPARalpha 0.00334179945806547 116 113 7 0.0619469026548673 0.0603448275862069
REAC REAC:R-HSA-381038 XBP1(S) activates chaperone genes 0.00334179945806547 47 70 4 0.0571428571428571 0.0851063829787234
REAC REAC:R-HSA-1989781 PPARA activates gene expression 0.00334179945806547 115 113 7 0.0619469026548673 0.0608695652173913
REAC REAC:R-HSA-381426 Regulation of Insulin-like Growth Factor (IGF) transport and uptake by Insulin-like Growth Factor Binding Proteins (IGFBPs) 0.00349372315135516 124 50 5 0.1 0.0403225806451613
REAC REAC:R-HSA-72766 Translation 0.00349372315135516 292 78 9 0.115384615384615 0.0308219178082192
REAC REAC:R-HSA-983170 Antigen Presentation: Folding, assembly and peptide loading of class I MHC 0.0045073529584392 25 61 3 0.0491803278688525 0.12
REAC REAC:R-HSA-381042 PERK regulates gene expression 0.028938958979557 32 91 3 0.032967032967033 0.09375
REAC REAC:R-HSA-9619665 EGR2 and SOX10-mediated initiation of Schwann cell myelination 0.0368949541929993 28 115 3 0.0260869565217391 0.107142857142857
REAC REAC:R-HSA-532668 N-glycan trimming in the ER and Calnexin/Calreticulin cycle 0.045553289462893 35 101 3 0.0297029702970297 0.0857142857142857
TF TF:M02106 Factor: NF-YA; motif: CRGCCAATCAGNRN 1.06411776744688e-12 1741 109 41 0.376146788990826 0.0235496840896037
TF TF:M03862_1 Factor: YB-1; motif: NNNNCCAATNN; match class: 1 7.78984978045327e-10 3120 59 34 0.576271186440678 0.0108974358974359
TF TF:M10006 Factor: NF-YC; motif: NNRRCCAATCAGNR 9.90190468701309e-09 2510 116 44 0.379310344827586 0.0175298804780877
TF TF:M07206 Factor: E2F-1; motif: NGGGCGGGARV 9.90190468701309e-09 14575 116 113 0.974137931034483 0.00775300171526587
TF TF:M10005 Factor: NF-YA; motif: NYRRCCAATCAGAR 2.15509140924918e-08 2225 74 31 0.418918918918919 0.0139325842696629
TF TF:M00287 Factor: NF-Y; motif: NNNRRCCAATSRGNNN 2.16741422591633e-08 1635 114 34 0.298245614035088 0.0207951070336391
TF TF:M04683 Factor: NF-YA; motif: YTCTSATTGGYYRN 2.67673624311184e-08 1657 114 34 0.298245614035088 0.0205190102595051
TF TF:M11529_1 Factor: E2F-2; motif: GCGCGCGCNCS; match class: 1 3.30261870516175e-08 14473 115 111 0.965217391304348 0.00766945346507289
TF TF:M10438_1 Factor: ZF5; motif: GGSGCGCGS; match class: 1 3.67808986110118e-08 14873 116 113 0.974137931034483 0.00759766018960533
TF TF:M09894_1 Factor: E2F-4; motif: SNGGGCGGGAANN; match class: 1 4.05988609283574e-08 13929 115 109 0.947826086956522 0.00782540024409505
TF TF:M10438 Factor: ZF5; motif: GGSGCGCGS 7.91896396783355e-08 16228 116 116 1 0.00714813901897954
TF TF:M00716_1 Factor: ZF5; motif: GSGCGCGR; match class: 1 8.45987393176044e-08 14106 116 110 0.948275862068966 0.00779810009924855
TF TF:M07302 Factor: NF-Y; motif: RGCCAATCRGN 1.19688608268682e-06 1576 76 24 0.315789473684211 0.0152284263959391
TF TF:M03805_1 Factor: YB-1; motif: CCAMTCNGMR; match class: 1 1.30280312045141e-06 3680 70 35 0.5 0.00951086956521739
TF TF:M02107 Factor: NF-YC; motif: NRGCCAATYAGMGC 1.7118463967614e-06 1001 75 19 0.253333333333333 0.018981018981019
TF TF:M11529 Factor: E2F-2; motif: GCGCGCGCNCS 2.17741814867688e-06 16263 115 114 0.991304347826087 0.00700977679394946
TF TF:M07250 Factor: E2F-1; motif: NNNSSCGCSAANN 2.27262801766345e-06 10703 93 77 0.827956989247312 0.00719424460431655
TF TF:M02106_1 Factor: NF-YA; motif: CRGCCAATCAGNRN; match class: 1 3.74471326815506e-06 217 57 9 0.157894736842105 0.0414746543778802
TF TF:M09816 Factor: NFYA; motif: RRCCAATCAGN 3.74471326815506e-06 1969 114 33 0.289473684210526 0.0167597765363128
TF TF:M00716 Factor: ZF5; motif: GSGCGCGR 6.53117672775851e-06 16103 116 114 0.982758620689655 0.00707942619387692
TF TF:M07222 Factor: NFYA; motif: AGNSYKCTGATTGGTNNR 6.71423201054776e-06 714 113 19 0.168141592920354 0.0266106442577031
TF TF:M00687 Factor: alpha-CP1; motif: CAGCCAATGAG 7.43917698132496e-06 2326 116 36 0.310344827586207 0.0154772141014617
TF TF:M00209 Factor: NF-Y; motif: NCTGATTGGYTASY 9.87909709756144e-06 3776 74 35 0.472972972972973 0.00926906779661017
TF TF:M09894 Factor: E2F-4; motif: SNGGGCGGGAANN 9.87909709756144e-06 16194 116 114 0.982758620689655 0.00703964431270841
TF TF:M11531 Factor: E2F-2; motif: GCGCGCGCGYW 1.24204928400309e-05 13270 70 66 0.942857142857143 0.00497362471740769
TF TF:M09636 Factor: MAZ; motif: GGGMGGGGSSGGGGGGGGGGGG 1.24204928400309e-05 16244 116 114 0.982758620689655 0.0070179758680128
TF TF:M11531_1 Factor: E2F-2; motif: GCGCGCGCGYW; match class: 1 1.24204928400309e-05 12351 116 99 0.853448275862069 0.00801554529997571
TF TF:M00775 Factor: NF-Y; motif: NNNNRRCCAATSR 1.33845846860498e-05 1428 76 21 0.276315789473684 0.0147058823529412
TF TF:M12152 Factor: Sp1; motif: NWRGCCACGCCCMCN 1.96577636816675e-05 7341 55 40 0.727272727272727 0.0054488489306634
TF TF:M12156 Factor: Sp2; motif: NTAAGYCCCGCCCMCTN 2.13811018607104e-05 4320 104 47 0.451923076923077 0.0108796296296296
TF TF:M03922 Factor: SP4; motif: NWRGCCACGCCCMCTYN 2.39484259391977e-05 6046 107 59 0.551401869158878 0.00975851802844856
TF TF:M02090 Factor: E2F-4; motif: GCGGGAAANA 2.44411819977246e-05 11966 103 87 0.844660194174757 0.00727060003342805
TF TF:M07395 Factor: Sp1; motif: NGGGGCGGGGN 2.75307098546059e-05 10640 115 89 0.773913043478261 0.00836466165413534
TF TF:M10006_1 Factor: NF-YC; motif: NNRRCCAATCAGNR; match class: 1 2.75307098546059e-05 388 57 10 0.175438596491228 0.0257731958762887
TF TF:M12186 Factor: BTEB4; motif: NCCACGCCCM 2.87584896817562e-05 9135 80 60 0.75 0.00656814449917898
TF TF:M03805 Factor: YB-1; motif: CCAMTCNGMR 4.3541278964599e-05 10161 115 86 0.747826086956522 0.00846373388446019
TF TF:M12173 Factor: GKLF; motif: NNCCMCRCCCN 4.36350628111043e-05 10023 71 57 0.802816901408451 0.00568692008380724
TF TF:M10072 Factor: sp4; motif: NNGNARGRGGCGGRGCNNRR 4.86730715742756e-05 10494 111 85 0.765765765765766 0.00809986659043263
TF TF:M09892 Factor: E2F-1; motif: NNNNGGCGGGAARN 5.71604875407358e-05 13528 115 102 0.88695652173913 0.00753991720875222
TF TF:M00196 Factor: Sp1; motif: NGGGGGCGGGGYN 5.71604875407358e-05 10233 115 86 0.747826086956522 0.00840418254666276
TF TF:M12151 Factor: Sp1; motif: NWRGCCMCGCCCMCN 5.71604875407358e-05 6821 70 45 0.642857142857143 0.00659727312710746
TF TF:M07206_1 Factor: E2F-1; motif: NGGGCGGGARV; match class: 1 7.06123574709532e-05 10849 115 89 0.773913043478261 0.00820352106184902
TF TF:M07395_1 Factor: Sp1; motif: NGGGGCGGGGN; match class: 1 7.74398749747972e-05 6334 111 61 0.54954954954955 0.00963056520366277
TF TF:M04516_1 Factor: E2F-1; motif: TTTGGCGCCAAA; match class: 1 8.69212268597837e-05 10227 68 55 0.808823529411765 0.00537792118900949
TF TF:M00803 Factor: E2F; motif: GGCGSG 9.44660289498559e-05 13190 115 100 0.869565217391304 0.00758150113722517
TF TF:M00333_1 Factor: ZF5; motif: NRNGNGCGCGCWN; match class: 1 0.000102874997204844 12401 116 97 0.836206896551724 0.00782194984275462
TF TF:M03924 Factor: YY1; motif: NNCGCCATTNN 0.000105664991352944 10084 54 45 0.833333333333333 0.00446251487504958
TF TF:M03862 Factor: YB-1; motif: NNNNCCAATNN 0.000109346564101399 9198 59 46 0.779661016949153 0.00500108719286801
TF TF:M00932 Factor: Sp1; motif: NNGGGGCGGGGNN 0.000129548105809495 10419 115 86 0.747826086956522 0.00825415107016028
TF TF:M08207_1 Factor: E2F-3:TBR2; motif: ANGTGYKANGGCGCSTTNNCRNNT; match class: 1 0.000148428244674328 15466 97 93 0.958762886597938 0.00601319022371654
TF TF:M08525_1 Factor: E2F-1:HES-7; motif: GGCRCGTGSYNNWNGGCGCSM; match class: 1 0.000148428244674328 15268 116 109 0.939655172413793 0.00713911448781766
TF TF:M09969 Factor: EKLF; motif: NGGGYGKGGCNNGG 0.000148428244674328 4589 82 39 0.475609756097561 0.0084985835694051
TF TF:M07084 Factor: E2F-4; motif: NGGCGGGAARN 0.000148428244674328 10834 115 88 0.765217391304348 0.00812257707218017
TF TF:M11417 Factor: c-Ets-2; motif: NACCGGAAGYRCTTCCGGTN 0.000148428244674328 14334 52 51 0.980769230769231 0.00355797404771871
TF TF:M00931 Factor: Sp1; motif: GGGGCGGGGC 0.000149592034436301 10281 115 85 0.739130434782609 0.00826767824141621
TF TF:M11530 Factor: E2F-2; motif: NWTTTGGCGCCAWWNN 0.000172750000900234 14593 85 80 0.941176470588235 0.0054820804495306
TF TF:M12351 Factor: TIEG1; motif: NCCCNSNCCCCGCCCCC 0.000184403269446716 12302 104 87 0.836538461538462 0.00707202080962445
TF TF:M03920 Factor: SP1; motif: RCCMCRCCCMC 0.000220432983748444 7283 104 62 0.596153846153846 0.00851297542221612
TF TF:M04823 Factor: E2F-4; motif: NNTTCCCGCCNN 0.000220432983748444 12747 115 97 0.843478260869565 0.00760963363928768
TF TF:M11883 Factor: pax-6; motif: NYACGCNTSRNYGCNYN 0.00022582069686483 13445 77 70 0.909090909090909 0.00520639642989959
TF TF:M11018 Factor: IRX-1; motif: NACRYNNNNNNNNRYGNN 0.000262978747291429 16955 104 103 0.990384615384615 0.00607490415806547
TF TF:M03807 Factor: SP2; motif: GNNGGGGGCGGGGSN 0.000299544474186964 8415 112 72 0.642857142857143 0.00855614973262032
TF TF:M09970 Factor: KLF3; motif: NNNNNNGGGCGGGGCNNGN 0.000299544474186964 7728 112 68 0.607142857142857 0.0087991718426501
TF TF:M01588 Factor: GKLF; motif: GCCMCRCCCNNN 0.000299544474186964 8944 112 75 0.669642857142857 0.00838550983899821
TF TF:M08205 Factor: E2F-1:Elk-1; motif: SGCGCSNNAMCGGAAGT 0.000299544474186964 14429 116 105 0.905172413793103 0.00727701157391365
TF TF:M09765 Factor: SP1; motif: NRGKGGGCGGGGCN 0.000299544474186964 7469 111 66 0.594594594594595 0.00883652430044183
TF TF:M11018_1 Factor: IRX-1; motif: NACRYNNNNNNNNRYGNN; match class: 1 0.000322745799117692 15920 104 100 0.961538461538462 0.00628140703517588
TF TF:M02089 Factor: E2F-3; motif: GGCGGGN 0.000322745799117692 13173 104 90 0.865384615384615 0.00683215668412662
TF TF:M01660_1 Factor: GABP-alpha; motif: CTTCCK; match class: 1 0.000322745799117692 5133 44 26 0.590909090909091 0.0050652639781804
TF TF:M04683_1 Factor: NF-YA; motif: YTCTSATTGGYYRN; match class: 1 0.000322745799117692 185 12 4 0.333333333333333 0.0216216216216216
TF TF:M04710 Factor: CHD2; motif: TCTCGCGAG 0.000375970149525788 14109 79 73 0.924050632911392 0.00517400240980934
TF TF:M07380_1 Factor: E2F-4; motif: NTTTCSCGCC; match class: 1 0.000388542774895103 7965 112 69 0.616071428571429 0.00866290018832392
TF TF:M04515_1 Factor: E2F-1; motif: WWTGGCGCCAAA; match class: 1 0.00040125909321974 12173 68 59 0.867647058823529 0.00484679208083463
TF TF:M08526_1 Factor: E2F-3:HES-7; motif: NNNSGCGCSNNNNNCRCGYGNN; match class: 1 0.00040125909321974 14997 116 107 0.922413793103448 0.00713476028539041
TF TF:M07129 Factor: Sp2; motif: GYCCCGCCYCYNNNN 0.000468117896629165 6260 111 58 0.522522522522523 0.00926517571884984
TF TF:M09826 Factor: BTEB3; motif: CCNNSCCNSCCCCKCCCCC 0.000547120927239255 11467 104 82 0.788461538461538 0.00715095491410133
TF TF:M09636_1 Factor: MAZ; motif: GGGMGGGGSSGGGGGGGGGGGG; match class: 1 0.000596241396042381 14096 115 102 0.88695652173913 0.0072360953461975
TF TF:M04826_1 Factor: p300; motif: ACNTCCG; match class: 1 0.000638278156949767 15260 99 93 0.939393939393939 0.00609436435124508
TF TF:M08525 Factor: E2F-1:HES-7; motif: GGCRCGTGSYNNWNGGCGCSM 0.000703544612313637 17065 116 114 0.982758620689655 0.00668033987694111
TF TF:M02052_1 Factor: EHF; motif: CSCGGAARTN; match class: 1 0.000734618011637212 4056 24 15 0.625 0.00369822485207101
TF TF:M03567 Factor: Sp2; motif: NYSGCCCCGCCCCCY 0.000791580611686076 7710 71 46 0.647887323943662 0.0059662775616083
TF TF:M11434 Factor: Elk-1; motif: NRSCGGAAGNN 0.00081864168113618 8219 115 71 0.617391304347826 0.00863852050127753
TF TF:M08224_1 Factor: Elk-1:Pax-1; motif: ACCGGAACTACGCWTSANTG; match class: 1 0.00081864168113618 2748 78 26 0.333333333333333 0.00946142649199418
TF TF:M11417_1 Factor: c-Ets-2; motif: NACCGGAAGYRCTTCCGGTN; match class: 1 0.000897779689735686 14041 49 47 0.959183673469388 0.0033473399330532
TF TF:M12183 Factor: KLF14; motif: NRCCACRCCCMCN 0.000897779689735686 6878 109 60 0.55045871559633 0.00872346612387322
TF TF:M10005_1 Factor: NF-YA; motif: NYRRCCAATCAGAR; match class: 1 0.000906293027769368 277 101 9 0.0891089108910891 0.0324909747292419
TF TF:M07250_1 Factor: E2F-1; motif: NNNSSCGCSAANN; match class: 1 0.000987424401159781 5515 76 39 0.513157894736842 0.0070716228467815
TF TF:M00333 Factor: ZF5; motif: NRNGNGCGCGCWN 0.00106510878504053 15072 112 103 0.919642857142857 0.00683386411889597
TF TF:M07380 Factor: E2F-4; motif: NTTTCSCGCC 0.00118620566810698 13022 112 94 0.839285714285714 0.0072185532176317
TF TF:M02059 Factor: ELK-1; motif: ACCGGAAGTN 0.00118620566810698 9423 116 78 0.672413793103448 0.00827761859280484
TF TF:M01837 Factor: FKLF; motif: BGGGNGGVMD 0.00118620566810698 5442 40 24 0.6 0.00441014332965821
TF TF:M01214_1 Factor: ESE-1; motif: NSMGGAARTN; match class: 1 0.00121159554247557 2176 24 11 0.458333333333333 0.00505514705882353
TF TF:M02055_1 Factor: ESE-1; motif: NSMGGAARTN; match class: 1 0.00121159554247557 2176 24 11 0.458333333333333 0.00505514705882353
TF TF:M05993 Factor: ZNF711; motif: NTGCGTGCGC 0.00122310119510774 38 27 3 0.111111111111111 0.0789473684210526
TF TF:M04869_1 Factor: Egr-1; motif: GCGCATGCG; match class: 1 0.00122310119510774 10253 69 53 0.768115942028985 0.00516921876523944
TF TF:M11603_1 Factor: TCF-1; motif: ACATCGRGRCGCTGW; match class: 1 0.00126179634451758 13184 89 77 0.865168539325843 0.00584041262135922
TF TF:M07039_1 Factor: ETF; motif: CCCCGCCCCYN; match class: 1 0.00150416236007497 13611 100 87 0.87 0.00639188891337888
TF TF:M10530 Factor: sp4; motif: NNNGCYCCGCCCCCY 0.00155303062389428 8227 111 68 0.612612612612613 0.00826546736355901
TF TF:M04710_1 Factor: CHD2; motif: TCTCGCGAG; match class: 1 0.00155303062389428 11477 74 60 0.810810810810811 0.00522784699834452
TF TF:M08441 Factor: AP-2gamma:Elk-1; motif: NGCCKNRGGSGRCGGAAGTG 0.00155875724895165 16345 116 111 0.956896551724138 0.0067910676047721
TF TF:M00428 Factor: E2F-1; motif: NKTSSCGC 0.00161604657871828 8947 77 53 0.688311688311688 0.00592377333184308
TF TF:M08457 Factor: ER71:SREBP-2; motif: NTSACGTGACGGAARY 0.00163585653509012 12052 73 61 0.835616438356164 0.00506140059741122
TF TF:M00196_1 Factor: Sp1; motif: NGGGGGCGGGGYN; match class: 1 0.00163585653509012 5919 111 54 0.486486486486487 0.00912316269640142
TF TF:M07115 Factor: NF-YB; motif: NNNYNRRCCAATCAG 0.00163585653509012 529 74 10 0.135135135135135 0.0189035916824197
TF TF:M04826 Factor: p300; motif: ACNTCCG 0.00170063059772246 17806 102 102 1 0.00572840615522857
TF TF:M00695 Factor: ETF; motif: GVGGMGG 0.0017150903325896 10430 116 83 0.71551724137931 0.00795781399808245
TF TF:M07409 Factor: BTEB2; motif: GCCCCRCCCH 0.00172334563367484 5198 82 39 0.475609756097561 0.00750288572527895
TF TF:M11061 Factor: HES-1; motif: GGCRCGTGNC 0.00186218192022533 6271 111 56 0.504504504504504 0.00892999521607399
TF TF:M11435_1 Factor: Elk-1; motif: NNCCGGAAGTN; match class: 1 0.00187447906258694 5745 44 26 0.590909090909091 0.00452567449956484
TF TF:M04748_1 Factor: GABP-alpha; motif: AACCGGAAR; match class: 1 0.00189676168396376 10368 51 41 0.803921568627451 0.00395447530864198
TF TF:M04950_1 Factor: Egr-1; motif: NGCGTGCGY; match class: 1 0.00189676168396376 5551 55 30 0.545454545454545 0.00540443163393983
TF TF:M03876 Factor: Kaiso; motif: GCMGGGRGCRGS 0.00202703539912751 13622 112 96 0.857142857142857 0.00704742328586111
TF TF:M00322 Factor: c-Myc:Max; motif: GCCAYGYGSN 0.00204683564761185 7873 102 61 0.598039215686274 0.00774799949193446
TF TF:M01168 Factor: SREBP; motif: NNNNYCACNCCANNN 0.00206437278274086 6651 106 56 0.528301886792453 0.00841978649827094
TF TF:M11490 Factor: LBP-1; motif: NRCCGGTNNNNACCGGYN 0.00207885513778758 6748 114 60 0.526315789473684 0.00889152341434499
TF TF:M00778 Factor: AhR; motif: NTNGCGTGNNN 0.00219892613587654 3526 56 23 0.410714285714286 0.00652297220646625
TF TF:M04516 Factor: E2F-1; motif: TTTGGCGCCAAA 0.00220712715394256 11383 103 79 0.766990291262136 0.00694017394360011
TF TF:M11235 Factor: OASIS; motif: YGCCACGTCANC 0.0022824766749756 368 111 10 0.0900900900900901 0.0271739130434783
TF TF:M04515 Factor: E2F-1; motif: WWTGGCGCCAAA 0.00232449506091387 13334 114 96 0.842105263157895 0.0071996400179991
TF TF:M01783 Factor: SP2; motif: GGGCGGGAC 0.00232449506091387 9148 112 73 0.651785714285714 0.0079798863139484
TF TF:M08205_1 Factor: E2F-1:Elk-1; motif: SGCGCSNNAMCGGAAGT; match class: 1 0.00238922801840464 10438 104 75 0.721153846153846 0.00718528453726768
TF TF:M09971 Factor: GKLF; motif: WGGGYGKGGC 0.00250174630276682 5546 66 34 0.515151515151515 0.00613054453660296
TF TF:M04869 Factor: Egr-1; motif: GCGCATGCG 0.00253254328807869 11232 63 51 0.80952380952381 0.00454059829059829
TF TF:M02089_1 Factor: E2F-3; motif: GGCGGGN; match class: 1 0.00260148433341505 9362 112 74 0.660714285714286 0.00790429395428327
TF TF:M00932_1 Factor: Sp1; motif: NNGGGGCGGGGNN; match class: 1 0.00260148433341505 6047 111 54 0.486486486486487 0.00893004795766496
TF TF:M00287_1 Factor: NF-Y; motif: NNNRRCCAATSRGNNN; match class: 1 0.00261943203153166 184 44 5 0.113636363636364 0.0271739130434783
TF TF:M03978 Factor: ETS1; motif: GCCGGAWGTACTTCCGGN 0.00261943203153166 12082 89 72 0.808988764044944 0.00595927826518788
TF TF:M10115 Factor: LRF; motif: NRGGGKCKY 0.00272591988628861 7623 65 41 0.630769230769231 0.00537845992391447
TF TF:M12165 Factor: BTEB2; motif: NCCACRCCCN 0.00272591988628861 4901 68 32 0.470588235294118 0.00652927973882881
TF TF:M00738 Factor: E2F-4:DP-1; motif: TTTSGCGC 0.00272591988628861 9812 73 53 0.726027397260274 0.00540154912352222
TF TF:M10072_1 Factor: sp4; motif: NNGNARGRGGCGGRGCNNRR; match class: 1 0.00272591988628861 6225 111 55 0.495495495495495 0.00883534136546185
TF TF:M11882 Factor: pax-6; motif: NYACGCNYSANYGMNCN 0.00277445740710348 15490 116 107 0.922413793103448 0.00690768237572627
TF TF:M11963_1 Factor: rfx2; motif: NGTTRCCATGGYAACN; match class: 1 0.00288170522659682 63 67 4 0.0597014925373134 0.0634920634920635
TF TF:M11075 Factor: Sohlh2; motif: NNCACGTGNN 0.00292422423784587 11927 69 57 0.826086956521739 0.00477907269221095
TF TF:M10071 Factor: Sp1; motif: NGGGGGCGGGGCCNGGGGGGGG 0.00316940130870585 8495 71 47 0.661971830985915 0.00553266627427899
TF TF:M09817_1 Factor: PAX5; motif: RNGCGTGACCNN; match class: 1 0.00316940130870585 6170 115 56 0.48695652173913 0.00907617504051864
TF TF:M12157 Factor: KLF15; motif: RCCACGCCCCCC 0.00319462461287722 3619 105 36 0.342857142857143 0.00994749930920144
TF TF:M12153 Factor: Sp3; motif: NGCCACGCCCMCN 0.00319462461287722 6205 107 53 0.495327102803738 0.00854149879129734
TF TF:M04797 Factor: Egr-1; motif: CCGCCCMCG 0.00322272838683645 5116 115 49 0.426086956521739 0.00957779515246286
TF TF:M08457_1 Factor: ER71:SREBP-2; motif: NTSACGTGACGGAARY; match class: 1 0.0032665603497117 5591 37 22 0.594594594594595 0.003934895367555
TF TF:M11963 Factor: rfx2; motif: NGTTRCCATGGYAACN 0.0032665603497117 66 67 4 0.0597014925373134 0.0606060606060606
TF TF:M00425 Factor: E2F; motif: TTTCGCGC 0.00341358018405676 11043 57 46 0.807017543859649 0.00416553472788192
TF TF:M02065 Factor: ER81; motif: RCCGGAARYN 0.0034679071461436 12550 116 93 0.801724137931034 0.00741035856573705
TF TF:M09892_1 Factor: E2F-1; motif: NNNNGGCGGGAARN; match class: 1 0.0034679071461436 9162 115 74 0.643478260869565 0.00807683911809649
TF TF:M09967 Factor: AP-2rep; motif: NGGGGCGGGGC 0.00351022388001482 4023 82 32 0.390243902439024 0.00795426298782003
TF TF:M08207 Factor: E2F-3:TBR2; motif: ANGTGYKANGGCGCSTTNNCRNNT 0.00364683144446209 17055 112 109 0.973214285714286 0.00639108765757842
TF TF:M10048 Factor: rfx2; motif: CNGTTGCCATGGCRACNN 0.00371938994300713 133 67 5 0.0746268656716418 0.037593984962406
TF TF:M01770_1 Factor: XBP-1; motif: WNNGMCACGTC; match class: 1 0.00371938994300713 4554 80 34 0.425 0.00746596398770312
TF TF:M01273 Factor: SP4; motif: SCCCCGCCCCS 0.00382513584276574 3296 82 28 0.341463414634146 0.00849514563106796
TF TF:M08313 Factor: GCMa:PEA3; motif: ATRCGGGCGGAAGTR 0.00391063130148013 15419 97 90 0.927835051546392 0.00583695440690058
TF TF:M00803_1 Factor: E2F; motif: GGCGSG; match class: 1 0.00410399558258234 10230 86 62 0.720930232558139 0.00606060606060606
TF TF:M01593_1 Factor: Zfx; motif: SNSCAGGCCKCGSCSS; match class: 1 0.00423420448523573 970 111 16 0.144144144144144 0.0164948453608247
TF TF:M00931_1 Factor: Sp1; motif: GGGGCGGGGC; match class: 1 0.00429099579689863 5905 82 41 0.5 0.0069432684165961
TF TF:M05720 Factor: ZNF134; motif: NGAAGACGGGGTCGGCNN 0.00429099579689863 18 103 3 0.029126213592233 0.166666666666667
TF TF:M07063 Factor: Sp1; motif: GGGGCGGGGC 0.00440838326312882 7696 111 63 0.567567567567568 0.00818607068607069
TF TF:M10435 Factor: Sp2; motif: GGGGCGGGG 0.00440838326312882 7696 111 63 0.567567567567568 0.00818607068607069
TF TF:M01240_1 Factor: BEN; motif: CAGCGRNV; match class: 1 0.00440838326312882 13227 112 93 0.830357142857143 0.00703107280562486
TF TF:M04631 Factor: RREB-1; motif: GCACCCMRACY 0.00480517451620933 710 107 13 0.121495327102804 0.0183098591549296
TF TF:M11058_1 Factor: Hey1; motif: NGCRCGYGYN; match class: 1 0.00495842791812236 10925 70 54 0.771428571428571 0.00494279176201373
TF TF:M01783_1 Factor: SP2; motif: GGGCGGGAC; match class: 1 0.00509852687805132 4333 112 42 0.375 0.00969305331179321
TF TF:M02011 Factor: HES-1; motif: GSCACGMGMC 0.00518692344330893 4259 100 38 0.38 0.00892228222587462
TF TF:M10680 Factor: HPX42B; motif: CGATTANCG 0.00523738866908452 1321 60 13 0.216666666666667 0.00984102952308857
TF TF:M00933 Factor: Sp1; motif: CCCCGCCCCN 0.00552333827896731 9715 104 70 0.673076923076923 0.00720535254760679
TF TF:M11066_1 Factor: HES-7; motif: GNCACGYGNN; match class: 1 0.00556127386046223 8172 69 44 0.63768115942029 0.00538423886441508
TF TF:M11530_1 Factor: E2F-2; motif: NWTTTGGCGCCAWWNN; match class: 1 0.00560849356142217 13449 85 73 0.858823529411765 0.00542791285597442
TF TF:M02064 Factor: c-ets-2; motif: ACCGGAWRTN 0.00562636542641388 10939 90 67 0.744444444444444 0.00612487430295274
TF TF:M00915 Factor: AP-2; motif: SNNNCCNCAGGCN 0.00617925869591258 9612 56 41 0.732142857142857 0.00426550145651269
TF TF:M11022 Factor: IRX2a; motif: ACRYGNNNNACRYGT 0.00624315879515482 9487 82 56 0.682926829268293 0.0059028143775693
TF TF:M00986 Factor: Churchill; motif: CGGGNN 0.00648579951052769 14197 112 97 0.866071428571429 0.0068324293864901
TF TF:M11098 Factor: Max; motif: NCACGTGNNNNNCACGTGN 0.00659578401621531 826 109 14 0.128440366972477 0.0169491525423729
TF TF:M11492 Factor: LBP9; motif: ACYRGTNNNNACYRGT 0.00659578401621531 7582 116 64 0.551724137931034 0.00844104457926668
TF TF:M01967_1 Factor: Pbx; motif: NKTGATTGACRKSN; match class: 1 0.00669397942361519 889 67 11 0.164179104477612 0.0123734533183352
TF TF:M08225_1 Factor: Elk-1:Pax-5; motif: ACCGGAACYACGCWTSANYG; match class: 1 0.00678155520936087 7993 44 30 0.681818181818182 0.00375328412360816
TF TF:M07277_1 Factor: BTEB2; motif: RGGGNGKGGN; match class: 1 0.00678155520936087 4149 111 40 0.36036036036036 0.0096408773198361
TF TF:M09658 Factor: Sp2; motif: GGSNNGGGGGCGGGGCCNGNGS 0.00678511909254042 5262 110 47 0.427272727272727 0.00893196503230711
TF TF:M11249 Factor: Luman; motif: NGCCACGTGKMN 0.00685353526207075 894 67 11 0.164179104477612 0.0123042505592841
TF TF:M08206 Factor: E2F-3:Prrxl1; motif: SGCGCTAATTNN 0.00685353526207075 11802 81 64 0.790123456790123 0.00542280969327233
TF TF:M11022_1 Factor: IRX2a; motif: ACRYGNNNNACRYGT; match class: 1 0.006953117405363 6246 56 31 0.553571428571429 0.00496317643291707
TF TF:M00976 Factor: AhR,; motif: NRCGTGNGN 0.006953117405363 4351 54 24 0.444444444444444 0.00551597333946219
TF TF:M04823_1 Factor: E2F-4; motif: NNTTCCCGCCNN; match class: 1 0.006953117405363 7850 115 65 0.565217391304348 0.00828025477707006
TF TF:M09972 Factor: BTEB2; motif: WGGGTGKGGCNGGN 0.006953117405363 9217 104 67 0.644230769230769 0.00726917652164479
TF TF:M11404 Factor: Fli-1; motif: NACCGGAARTN 0.006953117405363 8743 88 56 0.636363636363636 0.00640512409927942
TF TF:M10550 Factor: ZNF684; motif: MAAGGGGTGGACTGT 0.00696411246153951 15246 102 93 0.911764705882353 0.00609996064541519
TF TF:M04632 Factor: SREBP-1; motif: NNNGTGGGGTGAN 0.00715331181920236 4860 106 43 0.405660377358491 0.0088477366255144
TF TF:M03975 Factor: ERG; motif: ACCGGAARTN 0.00744352181031964 10002 116 78 0.672413793103448 0.00779844031193761
TF TF:M12164 Factor: BTEB2; motif: NMCACGCCCN 0.00746118243782961 2984 67 22 0.328358208955224 0.00737265415549598
TF TF:M11877 Factor: pax-2; motif: NCGTCACGCNYSRNYGCNYN 0.0075335578999414 11523 37 32 0.864864864864865 0.00277705458647922
TF TF:M00322_1 Factor: c-Myc:Max; motif: GCCAYGYGSN; match class: 1 0.0075335578999414 2862 93 27 0.290322580645161 0.00943396226415094
TF TF:M01253 Factor: CNOT3; motif: GGCCGCGSSS 0.00767598555025009 3926 114 39 0.342105263157895 0.00993377483443709
TF TF:M11433 Factor: Elk-1; motif: NRCCGGAAGTN 0.00767598555025009 7679 86 50 0.581395348837209 0.00651126448756348
TF TF:M08869 Factor: CLOCKBMAL; motif: NNNWCACGTGGN 0.00767598555025009 1848 35 11 0.314285714285714 0.00595238095238095
TF TF:M04106_1 Factor: RUNX2; motif: NRACCGCAAACCGCAN; match class: 1 0.00770056925160055 8372 63 41 0.650793650793651 0.00489727663640707
TF TF:M02090_1 Factor: E2F-4; motif: GCGGGAAANA; match class: 1 0.00799696589028577 6378 111 54 0.486486486486487 0.00846660395108184
TF TF:M00982 Factor: KROX; motif: CCCGCCCCCRCCCC 0.00813647061923344 7815 114 64 0.56140350877193 0.00818937939859245
TF TF:M04110 Factor: RUNX3; motif: NRACCGCANWAACCRCAN 0.00830941532337266 9266 115 73 0.634782608695652 0.0078782646233542
TF TF:M09766 Factor: ZNF592; motif: NSARNATGGAGKN 0.00830955765303469 7042 8 8 1 0.00113604089747231
TF TF:M11096 Factor: USF2; motif: NNCACGTGACN 0.00839284011316043 1561 69 15 0.217391304347826 0.00960922485586163
TF TF:M11435 Factor: Elk-1; motif: NNCCGGAAGTN 0.00840382115479953 11728 95 73 0.768421052631579 0.00622442019099591
TF TF:M04744 Factor: ATF-3; motif: GGCGCSSNSNGRTSACGTSA 0.00851057425352698 10089 114 77 0.675438596491228 0.00763207453662405
TF TF:M08523 Factor: E2F-1:TBR2; motif: NGGTGNNANGGCGCNNTNNCRNNN 0.00851057425352698 12160 91 72 0.791208791208791 0.00592105263157895
TF TF:M11052_1 Factor: Hey2; motif: NNCACGYGNN; match class: 1 0.00851057425352698 9523 69 48 0.695652173913043 0.0050404284364171
TF TF:M11399_1 Factor: Fli-1; motif: NACCGGAWWTCCGGTY; match class: 1 0.00851057425352698 11513 89 68 0.764044943820225 0.00590636671588639
TF TF:M02011_1 Factor: HES-1; motif: GSCACGMGMC; match class: 1 0.00852020563848998 845 111 14 0.126126126126126 0.0165680473372781
TF TF:M08377 Factor: meis1:Elf-1; motif: NTGCCGGAAGTN 0.00852571317608983 11275 92 69 0.75 0.00611973392461197
TF TF:M00246 Factor: Egr-2; motif: NTGCGTRGGCGK 0.008663797160444 6212 109 52 0.477064220183486 0.00837089504185447
TF TF:M05439 Factor: RREB-1; motif: GGGWCSA 0.00911116679434273 8635 73 47 0.643835616438356 0.00544296467863347
TF TF:M00426 Factor: E2F; motif: TTTSGCGS 0.00911116679434273 11885 87 68 0.781609195402299 0.00572149768615902
TF TF:M03567_1 Factor: Sp2; motif: NYSGCCCCGCCCCCY; match class: 1 0.00911116679434273 3614 104 34 0.326923076923077 0.00940785832872164
TF TF:M11535 Factor: E2F-4; motif: TTTTGGCGCCAWWN 0.00963229740956711 10884 84 62 0.738095238095238 0.00569643513414186
TF TF:M12158_1 Factor: KLF15; motif: NCCMCGCCCMCN; match class: 1 0.00963229740956711 6004 105 49 0.466666666666667 0.00816122584943371
TF TF:M12158 Factor: KLF15; motif: NCCMCGCCCMCN 0.00963229740956711 11088 109 79 0.724770642201835 0.00712481962481962
TF TF:M01660 Factor: GABP-alpha; motif: CTTCCK 0.00963229740956711 11116 115 83 0.721739130434783 0.00746671464555596
TF TF:M11066 Factor: HES-7; motif: GNCACGYGNN 0.00963229740956711 11507 60 48 0.8 0.00417137394629356
TF TF:M07042_1 Factor: HES-1; motif: NNCKYGTGNNN; match class: 1 0.00963229740956711 661 29 6 0.206896551724138 0.00907715582450832
TF TF:M04097_1 Factor: RFX3; motif: NGTTRCCATGGYAACN; match class: 1 0.00963229740956711 97 67 4 0.0597014925373134 0.0412371134020619
TF TF:M07354 Factor: Egr-1; motif: GCGGGGGCGG 0.00963229740956711 7801 29 21 0.724137931034483 0.00269196256890142
TF TF:M12166 Factor: CPBP; motif: NGCCACGCCCN 0.00963229740956711 1328 65 13 0.2 0.00978915662650602
TF TF:M02062 Factor: Erg; motif: ACCGGAAGTN 0.00963229740956711 8056 116 66 0.568965517241379 0.00819265143992056
TF TF:M04950 Factor: Egr-1; motif: NGCGTGCGY 0.00963229740956711 10935 115 82 0.71304347826087 0.00749885688157293
TF TF:M09973 Factor: CPBP; motif: GNNRGGGHGGGGNNGGGRN 0.00980677241262826 10853 75 56 0.746666666666667 0.00515986363217544
TF TF:M09991_1 Factor: N-Myc; motif: NGCCACGTGSNN; match class: 1 0.0098656539574258 329 37 5 0.135135135135135 0.0151975683890578
TF TF:M11393_1 Factor: Erg; motif: NACCGGATATCCGGTN; match class: 1 0.0100404333587067 13665 66 58 0.878787878787879 0.00424442005122576
TF TF:M01240 Factor: BEN; motif: CAGCGRNV 0.0102284069785446 16498 112 106 0.946428571428571 0.00642502121469269
TF TF:M08526 Factor: E2F-3:HES-7; motif: NNNSGCGCSNNNNNCRCGYGNN 0.0104905583465036 16867 116 111 0.956896551724138 0.00658089761071916
TF TF:M04467 Factor: HNF4A; motif: RRGGTCAAAGTCCANN 0.0104905583465036 1641 18 7 0.388888888888889 0.00426569165143205
TF TF:M04691_1 Factor: Kaiso; motif: TCTCGCGAG; match class: 1 0.0105491930019201 10488 46 36 0.782608695652174 0.0034324942791762
TF TF:M02070 Factor: TEL1; motif: CNCGGAANNN 0.0110481606549775 10837 45 36 0.8 0.00332195256989942
TF TF:M09626 Factor: HNF-4alpha; motif: NRGNNCAAAGTYCA 0.0111805684333769 1925 5 4 0.8 0.00207792207792208
TF TF:M11490_1 Factor: LBP-1; motif: NRCCGGTNNNNACCGGYN; match class: 1 0.0111805684333769 5988 114 52 0.456140350877193 0.00868403473613895
TF TF:M11393 Factor: Erg; motif: NACCGGATATCCGGTN 0.0111805684333769 14105 66 59 0.893939393939394 0.00418291386033322
TF TF:M10111 Factor: ZF5; motif: NGAGCGCGC 0.0111805684333769 2647 93 25 0.268817204301075 0.00944465432565168
TF TF:M02052 Factor: EHF; motif: CSCGGAARTN 0.0116344989125704 10107 29 24 0.827586206896552 0.00237459186702286
TF TF:M10086 Factor: TAFII250; motif: RARRWGGCGGMGGNGR 0.0116418493543182 9262 34 26 0.764705882352941 0.00280716907795293
TF TF:M01593 Factor: Zfx; motif: SNSCAGGCCKCGSCSS 0.0116780154660489 4163 111 39 0.351351351351351 0.0093682440547682
TF TF:M07356 Factor: HIF2A; motif: ACGTGNNN 0.0116780154660489 1852 88 19 0.215909090909091 0.0102591792656587
TF TF:M07226 Factor: SP1; motif: NCCCCKCCCCC 0.0120103722915871 8292 104 61 0.586538461538462 0.00735648818137964
TF TF:M00981_1 Factor: CREB,; motif: NTGACGTNA; match class: 1 0.0120103722915871 2904 115 31 0.269565217391304 0.0106749311294766
TF TF:M04107 Factor: RUNX2; motif: WRACCGCANWAACCGCAN 0.0120103722915871 12351 112 87 0.776785714285714 0.00704396405149381
TF TF:M12160_1 Factor: KLF15; motif: RCCMCRCCCMCN; match class: 1 0.0120265293248551 8031 109 62 0.568807339449541 0.0077200846718964
TF TF:M03988 Factor: FLI1; motif: ACCGGAARTN 0.0122971519138458 8318 88 53 0.602272727272727 0.00637172397210868
TF TF:M08304_1 Factor: FOXO1A:ETV7; motif: NWMAACAGGAMNNNCTTCCNN; match class: 1 0.0126529290735412 7620 30 21 0.7 0.00275590551181102
TF TF:M09991 Factor: N-Myc; motif: NGCCACGTGSNN 0.0128492140315929 1842 69 16 0.231884057971014 0.00868621064060804
TF TF:M00139 Factor: AhR; motif: CCYCNRRSTNGCGTGASA 0.0128492140315929 3728 15 9 0.6 0.00241416309012876
TF TF:M10071_1 Factor: Sp1; motif: NGGGGGCGGGGCCNGGGGGGGG; match class: 1 0.0129386808685806 4623 82 33 0.402439024390244 0.00713822193380921
TF TF:M01298 Factor: MECP2; motif: CCGGSNNNANNAWWT 0.0129386808685806 1290 17 6 0.352941176470588 0.00465116279069767
TF TF:M03860_1 Factor: USF2; motif: NNNCCACGTGACN; match class: 1 0.0129950550402534 971 69 11 0.159420289855072 0.0113285272914521
TF TF:M11399 Factor: Fli-1; motif: NACCGGAWWTCCGGTY 0.013491476776417 12977 89 73 0.820224719101124 0.00562533713493103
TF TF:M01770 Factor: XBP-1; motif: WNNGMCACGTC 0.0137546671090459 11003 92 67 0.728260869565217 0.0060892483868036
TF TF:M09816_1 Factor: NFYA; motif: RRCCAATCAGN; match class: 1 0.0137546671090459 278 12 3 0.25 0.0107913669064748
TF TF:M03807_1 Factor: SP2; motif: GNNGGGGGCGGGGSN; match class: 1 0.0137546671090459 4199 104 37 0.355769230769231 0.00881162181471779
TF TF:M09723 Factor: BTEB1; motif: GGGGGCGGGGCNGSGGGNGS 0.0138715216950828 10156 110 74 0.672727272727273 0.00728633320204805
TF TF:M11256 Factor: AIBZIP; motif: NGCCACGTCAYN 0.0140496062793147 1323 114 18 0.157894736842105 0.0136054421768707
TF TF:M08767_1 Factor: HES-1; motif: GNCACGTGNC; match class: 1 0.0140496062793147 7709 86 49 0.569767441860465 0.00635620703074329
TF TF:M04744_1 Factor: ATF-3; motif: GGCGCSSNSNGRTSACGTSA; match class: 1 0.0140496062793147 4889 116 45 0.387931034482759 0.00920433626508489
TF TF:M08390 Factor: A-Myb:Elf-1; motif: NMCCGGAACCGTTA 0.014173062755522 11072 87 64 0.735632183908046 0.00578034682080925
TF TF:M09947 Factor: HNF-4alpha; motif: NRGKNCAAAGTCCA 0.0143664760820366 2111 5 4 0.8 0.00189483657034581
TF TF:M12345 Factor: Zbtb37; motif: NYACCGCRNTCACCGCR 0.0143664760820366 5505 79 36 0.455696202531646 0.00653950953678474
TF TF:M08235 Factor: ERF:TBR2; motif: NNTNRCACCGGAWGY 0.0143664760820366 272 104 7 0.0673076923076923 0.0257352941176471
TF TF:M10530_1 Factor: sp4; motif: NNNGCYCCGCCCCCY; match class: 1 0.0143664760820366 3780 111 36 0.324324324324324 0.00952380952380952
TF TF:M08676_1 Factor: C/EBPgamma:Elf-1; motif: TKRCGHAATWSCGGAAGT; match class: 1 0.0145367800516465 2364 31 11 0.354838709677419 0.00465313028764805
TF TF:M11880_1 Factor: pax-6; motif: NYACGCWTSANYGMNCN; match class: 1 0.0151698490332869 7046 10 9 0.9 0.00127732046551235
TF TF:M08313_1 Factor: GCMa:PEA3; motif: ATRCGGGCGGAAGTR; match class: 1 0.0153438003645641 9721 97 64 0.65979381443299 0.00658368480608991
TF TF:M12160 Factor: KLF15; motif: RCCMCRCCCMCN 0.0153631677394062 12729 110 87 0.790909090909091 0.00683478670751827
TF TF:M07467 Factor: Six-4; motif: GGCTCARRTTWCN 0.015423659416132 568 67 8 0.119402985074627 0.0140845070422535
TF TF:M08441_1 Factor: AP-2gamma:Elk-1; motif: NGCCKNRGGSGRCGGAAGTG; match class: 1 0.0156567619824798 12761 114 90 0.789473684210526 0.0070527388135726
TF TF:M08911 Factor: CTCF; motif: NCCRSTAGGGGGCGC 0.015741393389297 9094 112 69 0.616071428571429 0.00758742027710578
TF TF:M00986_1 Factor: Churchill; motif: CGGGNN; match class: 1 0.015741393389297 10357 112 76 0.678571428571429 0.00733803224872067
TF TF:M09820 Factor: USF2; motif: NNNGGTCACGTGRYNN 0.0159709600835912 2091 69 17 0.246376811594203 0.00813008130081301
TF TF:M12351_1 Factor: TIEG1; motif: NCCCNSNCCCCGCCCCC; match class: 1 0.0160332814375181 8180 17 14 0.823529411764706 0.00171149144254279
TF TF:M09868 Factor: ATF-3; motif: GGTSACGTGAN 0.016165028321973 6391 87 43 0.494252873563218 0.00672821154748866
TF TF:M11601 Factor: TCF-1; motif: ACATCGRGRCGCTGW 0.0161739450740959 14823 68 62 0.911764705882353 0.00418268906429198
TF TF:M03929_1 Factor: ZBTB7C; motif: NCGACCACCGNN; match class: 1 0.0161804170590265 303 12 3 0.25 0.0099009900990099
TF TF:M11434_1 Factor: Elk-1; motif: NRSCGGAAGNN; match class: 1 0.0165452272095876 2935 34 13 0.382352941176471 0.00442930153321976
TF TF:M11492_1 Factor: LBP9; motif: ACYRGTNNNNACYRGT; match class: 1 0.0167025427980985 6005 116 52 0.448275862068966 0.00865945045795171
TF TF:M00516 Factor: E2F-1; motif: TTTSGCGCGMNR 0.0172767077629317 6904 23 16 0.695652173913043 0.00231749710312862
TF TF:M09603 Factor: Egr-1; motif: NNNNNGYGKGGGNGGGNN 0.0174144141860589 4627 110 41 0.372727272727273 0.00886103306678193
TF TF:M10098_1 Factor: DP-1; motif: NRNNGGCGGGAANN; match class: 1 0.0175081736730188 2168 104 23 0.221153846153846 0.0106088560885609
TF TF:M11427 Factor: PEA3; motif: NACCGGAAGTN 0.0175081736730188 10585 86 61 0.709302325581395 0.0057628719886632
TF TF:M00695_1 Factor: ETF; motif: GVGGMGG; match class: 1 0.0175081736730188 7032 115 58 0.504347826086956 0.00824800910125142
TF TF:M09606_1 Factor: nerf; motif: NRRNSCGGAAGNRNNNN; match class: 1 0.0176303172042528 1704 63 14 0.222222222222222 0.00821596244131455
TF TF:M02055 Factor: ESE-1; motif: NSMGGAARTN 0.0176303172042528 7559 29 20 0.689655172413793 0.00264585262600873
TF TF:M01214 Factor: ESE-1; motif: NSMGGAARTN 0.0176303172042528 7559 29 20 0.689655172413793 0.00264585262600873
TF TF:M08767 Factor: HES-1; motif: GNCACGTGNC 0.0178613246654223 7813 86 49 0.569767441860465 0.00627159861768847
TF TF:M01165 Factor: Elk-1; motif: RACCGGAAGTR 0.0178834704184843 7773 114 62 0.543859649122807 0.00797632831596552
TF TF:M11603 Factor: TCF-1; motif: ACATCGRGRCGCTGW 0.0178834704184843 16361 101 95 0.940594059405941 0.0058064910457796
TF TF:M08226 Factor: Elk-1:Pax-9; motif: ACCGGAACYACGCWYSANTG 0.0178834704184843 12039 44 37 0.840909090909091 0.00307334496220616
TF TF:M11256_1 Factor: AIBZIP; motif: NGCCACGTCAYN; match class: 1 0.0182246064196183 75 111 4 0.036036036036036 0.0533333333333333
TF TF:M11533 Factor: E2F-1; motif: NTTTTGGCGCCAWWWN 0.01826537494957 13105 81 67 0.827160493827161 0.00511255246089279
TF TF:M04106 Factor: RUNX2; motif: NRACCGCAAACCGCAN 0.0186466917509138 13833 114 95 0.833333333333333 0.00686763536470758
TF TF:M03928 Factor: ZBTB7B; motif: NCGACCACCGAA 0.0186974826935317 633 63 8 0.126984126984127 0.0126382306477093
TF TF:M08875 Factor: E2F; motif: NNTTTCGCGCN 0.0188676101331646 6203 103 48 0.466019417475728 0.00773819119780751
TF TF:M00217_1 Factor: USF; motif: NCACGTGN; match class: 1 0.0188676101331646 1248 76 13 0.171052631578947 0.0104166666666667
TF TF:M10432 Factor: MAZ; motif: GGGMGGGGS 0.0189873510524497 9259 73 48 0.657534246575342 0.00518414515606437
TF TF:M03860 Factor: USF2; motif: NNNCCACGTGACN 0.0189873510524497 3576 70 24 0.342857142857143 0.00671140939597315
TF TF:M01588_1 Factor: GKLF; motif: GCCMCRCCCNNN; match class: 1 0.0189873510524497 3962 82 29 0.353658536585366 0.00731953558808683
TF TF:M07300 Factor: NF-1C; motif: TTGGCNN 0.0190788041031704 6211 116 53 0.456896551724138 0.00853324746417646
TF TF:M09887 Factor: CREB1; motif: NRRTGACGTMA 0.0192162576875504 5419 33 18 0.545454545454545 0.0033216460601587
TF TF:M11227 Factor: ATF-6; motif: TGRTGACGTGGCAN 0.0200500440516369 201 111 6 0.0540540540540541 0.0298507462686567
TF TF:M00243 Factor: Egr-1; motif: WTGCGTGGGCGK 0.0200837319654275 5356 115 47 0.408695652173913 0.00877520537714713
TF TF:M03896 Factor: EGR1; motif: NACGCCCACGCANW 0.0200837319654275 6129 115 52 0.452173913043478 0.00848425518029042
TF TF:M09606 Factor: nerf; motif: NRRNSCGGAAGNRNNNN 0.0200972025931389 6249 34 20 0.588235294117647 0.00320051208193311
TF TF:M00245 Factor: Egr-3; motif: NTGCGTGGGCGK 0.0201605000065694 7313 61 35 0.573770491803279 0.00478599753862984
TF TF:M09897 Factor: Egr-1; motif: NNNNGCGKGGGYGGNRN 0.0208880763892217 4244 106 37 0.349056603773585 0.0087181903864279
TF TF:M09670 Factor: USF2; motif: NGGTCACGTGNNSNNNNNN 0.0208880763892217 2368 69 18 0.260869565217391 0.00760135135135135
TF TF:M08232_1 Factor: Elk-1:TEF; motif: RCCGGAAGTTACGTAAN; match class: 1 0.0210632037877645 1294 8 4 0.5 0.00309119010819165
TF TF:M11424_1 Factor: Erm; motif: NNSCGGAWGYN; match class: 1 0.0211698309405282 2835 24 10 0.416666666666667 0.00352733686067019
TF TF:M00981 Factor: CREB,; motif: NTGACGTNA 0.0212325384375491 8345 116 66 0.568965517241379 0.0079089275014979
TF TF:M11881 Factor: pax-6; motif: NYACGCNTSANYGCNYN 0.0212325384375491 13174 77 64 0.831168831168831 0.00485805374221952
TF TF:M04934_1 Factor: TR4; motif: ACCCCGS; match class: 1 0.0213257535079975 15478 70 65 0.928571428571429 0.00419950898048844
TF TF:M09896 Factor: E2F-7; motif: GRGGCGGGAANNN 0.0213257535079975 9927 56 40 0.714285714285714 0.00402941472751083
TF TF:M01665 Factor: IRF-8; motif: AGTTTCW 0.0214200439043917 4771 9 7 0.777777777777778 0.00146719765248376
TF TF:M11425_1 Factor: PEA3; motif: NACCGGAAGTN; match class: 1 0.0214200439043917 2330 24 9 0.375 0.00386266094420601
TF TF:M00008 Factor: Sp1; motif: GGGGCGGGGT 0.0214200439043917 10055 82 56 0.682926829268293 0.00556936847339632
TF TF:M07300_1 Factor: NF-1C; motif: TTGGCNN; match class: 1 0.0214200439043917 1188 112 16 0.142857142857143 0.0134680134680135
TF TF:M09641 Factor: NRF-1; motif: SYGCGCMTGCGCRNNGSN 0.0214200439043917 3222 114 32 0.280701754385965 0.00993171942892613
TF TF:M00411 Factor: HNF4alpha1; motif: NRGGNCAAAGGTCAN 0.0215145014761164 1811 10 5 0.5 0.00276090557702927
TF TF:M02065_1 Factor: ER81; motif: RCCGGAARYN; match class: 1 0.0215275052511026 6749 28 18 0.642857142857143 0.0026670617869314
TF TF:M08213_1 Factor: Elk-1:TBR2; motif: TNRCACCGGAAGN; match class: 1 0.0220341383475988 1417 113 18 0.15929203539823 0.0127028934368384
TF TF:M00055_1 Factor: N-Myc; motif: NNCCACGTGNNN; match class: 1 0.0227825603111769 1452 76 14 0.184210526315789 0.00964187327823691
TF TF:M01703 Factor: Gli2; motif: GACCACCCANG 0.0231898542167974 3764 32 14 0.4375 0.00371944739638682
TF TF:M04748 Factor: GABP-alpha; motif: AACCGGAAR 0.0231898542167974 16027 54 52 0.962962962962963 0.00324452486429151
TF TF:M00975_1 Factor: RFX; motif: SHGTTGCSN; match class: 1 0.0234502571661212 1006 5 3 0.6 0.00298210735586481
TF TF:M01873_1 Factor: Egr-1; motif: GCGGGGGCGG; match class: 1 0.0239759897186755 2672 115 28 0.243478260869565 0.0104790419161677
TF TF:M07601_1 Factor: C-Myc; motif: NGCCACGTGNN; match class: 1 0.0239846816200245 4180 76 28 0.368421052631579 0.00669856459330144
TF TF:M00113 Factor: CREB; motif: NNGNTGACGTNN 0.0240262992772218 4801 86 34 0.395348837209302 0.0070818579462612
TF TF:M08913_1 Factor: FLI-1; motif: NAYTTCCGGT; match class: 1 0.0241783525156878 3055 116 31 0.267241379310345 0.0101472995090016
TF TF:M11397_1 Factor: Erg; motif: NACCGGATATCCGGTN; match class: 1 0.0243113219221354 11731 89 67 0.752808988764045 0.00571136305515301
TF TF:M00177 Factor: CREB; motif: NSTGACGTAANN 0.0245236721527738 5221 116 46 0.396551724137931 0.00881057268722467
TF TF:M00933_1 Factor: Sp1; motif: CCCCGCCCCN; match class: 1 0.0245671117508065 5166 111 44 0.396396396396396 0.00851722802942315
TF TF:M07617 Factor: Sp4; motif: SCCCCKCCCCCSN 0.0245671117508065 3595 104 32 0.307692307692308 0.00890125173852573
TF TF:M04714_1 Factor: Elf-1; motif: ACTTCCGGG; match class: 1 0.0245671117508065 2659 26 10 0.384615384615385 0.00376081233546446
TF TF:M09734 Factor: ZNF692; motif: SYNGGSCCCASCCNC 0.0245977394449271 11678 57 45 0.789473684210526 0.00385339955471827
TF TF:M12162 Factor: KLF3; motif: GRCCACGCCCN 0.0248670723723116 1163 65 11 0.169230769230769 0.00945829750644884
TF TF:M00939 Factor: E2F; motif: TTTSGCGSG 0.0248670723723116 6433 23 15 0.652173913043478 0.00233172703248873
TF TF:M04696 Factor: YY1; motif: GCCGCCATNTTGNNNNNGGNCN 0.0248670723723116 7819 79 45 0.569620253164557 0.00575521166389564
TF TF:M07277 Factor: BTEB2; motif: RGGGNGKGGN 0.0248670723723116 8492 111 64 0.576576576576577 0.00753650494583137
TF TF:M08869_1 Factor: CLOCKBMAL; motif: NNNWCACGTGGN; match class: 1 0.0248670723723116 137 69 4 0.0579710144927536 0.0291970802919708
TF TF:M11541_1 Factor: Foxn2; motif: NNGCGTCNNNNNGACGCNN; match class: 1 0.0250399174640795 5493 85 37 0.435294117647059 0.00673584562170035
TF TF:M02063 Factor: c-ets-1; motif: ACCGGAWGTN 0.0258258141830978 7600 116 61 0.525862068965517 0.00802631578947368
TF TF:M02056_1 Factor: ELF4; motif: NCCGGAARTN; match class: 1 0.0259162328121751 1291 116 17 0.146551724137931 0.0131680867544539
TF TF:M07615 Factor: Sp3; motif: GGGGCGGGGSNN 0.0260247837454706 6807 111 54 0.486486486486487 0.00793301013662406
TF TF:M05361 Factor: Sp6; motif: WGGGCGG 0.0265510301057127 8578 14 12 0.857142857142857 0.00139892748892516
TF TF:M00088_1 Factor: Ik-3; motif: TNYTGGGAATACC; match class: 1 0.0265510301057127 1019 34 7 0.205882352941176 0.00686947988223749
TF TF:M08993 Factor: ZNF777; motif: GTCCGYCCCGTCSAACAAT 0.0265510301057127 10617 110 75 0.681818181818182 0.00706414241311105
TF TF:M11880 Factor: pax-6; motif: NYACGCWTSANYGMNCN 0.0265510301057127 13087 50 43 0.86 0.00328570336975625
TF TF:M05444 Factor: CPBP; motif: NGGGCGG 0.0265510301057127 8578 14 12 0.857142857142857 0.00139892748892516
TF TF:M05332 Factor: Sp2; motif: WGGGCGG 0.0265510301057127 8578 14 12 0.857142857142857 0.00139892748892516
TF TF:M00341 Factor: GABP; motif: VCCGGAAGNGCR 0.0265510301057127 8224 70 42 0.6 0.00510700389105058
TF TF:M06948 Factor: Sp2; motif: TGGGCGCGCCCA 0.0265510301057127 8864 115 68 0.591304347826087 0.00767148014440433
TF TF:M08959_1 Factor: PAX-7; motif: NASCGTRACKAAT; match class: 1 0.0265510301057127 3856 114 36 0.315789473684211 0.00933609958506224
TF TF:M10121 Factor: ZFX; motif: SNAGGCCNCR 0.0265510301057127 3997 80 28 0.35 0.00700525394045534
TF TF:M11883_1 Factor: pax-6; motif: NYACGCNTSRNYGCNYN; match class: 1 0.027549333254521 7768 41 26 0.634146341463415 0.0033470648815654
TF TF:M01752 Factor: ERG; motif: ACCGGAART 0.0278479132707819 9474 116 72 0.620689655172414 0.00759974667511083
TF TF:M08451_1 Factor: Elk-1:HOXA1; motif: ACCGGAAGTAATTA; match class: 1 0.0278479132707819 2584 23 9 0.391304347826087 0.00348297213622291
TF TF:M00940 Factor: E2F-1; motif: NTTTCGCGCS 0.0278479132707819 7802 61 36 0.590163934426229 0.00461420148679826
TF TF:M01822_1 Factor: CPBP; motif: SNCCCNN; match class: 1 0.0278479132707819 18663 116 116 1 0.00621550661737127
TF TF:M00917_1 Factor: CREB; motif: CNNTGACGTMA; match class: 1 0.0278479132707819 1590 96 17 0.177083333333333 0.0106918238993711
TF TF:M05438 Factor: Osx; motif: WGGGCGGGTS 0.0278479132707819 181 55 4 0.0727272727272727 0.0220994475138122
TF TF:M11541 Factor: Foxn2; motif: NNGCGTCNNNNNGACGCNN 0.0279772728532991 5751 85 38 0.447058823529412 0.0066075465136498
TF TF:M11759 Factor: HNF-4alpha; motif: RRGGTCAAAGTCCAN 0.0279772728532991 2090 18 7 0.388888888888889 0.00334928229665072
TF TF:M00187_1 Factor: USF; motif: GYCACGTGNC; match class: 1 0.0284584764152814 1528 75 14 0.186666666666667 0.00916230366492147
TF TF:M03893 Factor: WT1; motif: GNGGGGGCGGGG 0.0293369728529739 8290 104 59 0.567307692307692 0.00711700844390832
TF TF:M02036 Factor: WT1; motif: CGCCCCCNCN 0.0293378750630971 9767 115 73 0.634782608695652 0.00747414764001229
TF TF:M11601_1 Factor: TCF-1; motif: ACATCGRGRCGCTGW; match class: 1 0.0300123043746987 11053 63 47 0.746031746031746 0.00425223921107392
TF TF:M11382 Factor: ESE-1; motif: NWTRCGGAWGCN 0.0300123043746987 10339 44 33 0.75 0.00319179804623271
TF TF:M00236 Factor: Arnt; motif: NDDNNCACGTGNNNNN 0.0300123043746987 2210 77 18 0.233766233766234 0.0081447963800905
TF TF:M01260_1 Factor: STAT1; motif: NNTTTCYNGGAARNNNNNNNNN; match class: 1 0.0302664457940835 657 8 3 0.375 0.0045662100456621
TF TF:M09973_1 Factor: CPBP; motif: GNNRGGGHGGGGNNGGGRN; match class: 1 0.0306844385742869 6607 110 52 0.472727272727273 0.0078704404419555
TF TF:M10491_1 Factor: ZNF586; motif: CAGGCCYRGAGG; match class: 1 0.0309308535187978 7720 111 59 0.531531531531532 0.00764248704663212
TF TF:M07410 Factor: RFX2; motif: GTYNCCATGGCAACNGNNN 0.0315085660511489 521 67 7 0.104477611940299 0.0134357005758157
TF TF:M11255 Factor: AIBZIP; motif: YGCCACGTGGCN 0.0320565400623768 716 37 6 0.162162162162162 0.00837988826815642
TF TF:M11181_1 Factor: MyoD; motif: CGNCAGSTGTYN; match class: 1 0.0320565400623768 488 72 7 0.0972222222222222 0.014344262295082
TF TF:M00378_1 Factor: Pax-4; motif: NNNNNYCACCCB; match class: 1 0.0320565400623768 14711 115 99 0.860869565217391 0.00672965807898851
TF TF:M10104 Factor: YY1; motif: CAARATGGCGGC 0.0320565400623768 6071 79 37 0.468354430379747 0.0060945478504365
TF TF:M00431 Factor: E2F-1; motif: TTTSGCGS 0.0320565400623768 7257 61 34 0.557377049180328 0.00468513159707868
TF TF:M11882_1 Factor: pax-6; motif: NYACGCNYSANYGMNCN; match class: 1 0.0320565400623768 11423 41 33 0.804878048780488 0.00288890834281712
TF TF:M07067 Factor: USF1; motif: NNNNGTCACGTGGN 0.0320565400623768 3152 69 21 0.304347826086957 0.00666243654822335
TF TF:M08487 Factor: GCMa:Erg; motif: ATGCGGGCGGAARKG 0.0320565400623768 13942 116 96 0.827586206896552 0.00688566920097547
TF TF:M08226_1 Factor: Elk-1:Pax-9; motif: ACCGGAACYACGCWYSANTG; match class: 1 0.0320565400623768 5604 44 22 0.5 0.00392576730906495
TF TF:M08884 Factor: GCM; motif: NNNNATGMGGGN 0.0320565400623768 1185 5 3 0.6 0.00253164556962025
TF TF:M00346_1 Factor: GATA-1; motif: NCWGATAACA; match class: 1 0.0320565400623768 679 8 3 0.375 0.00441826215022091
TF TF:M00039_1 Factor: CREB; motif: TGACGTMA; match class: 1 0.0324160227553599 1482 96 16 0.166666666666667 0.0107962213225371
TF TF:M01242 Factor: MTF-1; motif: GTGTGCANMACTTTGCGCAC 0.0324160227553599 3931 53 20 0.377358490566038 0.00508776392775375
TF TF:M00017_1 Factor: ATF; motif: CNSTGACGTNNNYC; match class: 1 0.0324160227553599 2222 96 21 0.21875 0.00945094509450945
TF TF:M10886 Factor: PRX-2; motif: NYAATTAN 0.0330598044254616 1156 59 10 0.169491525423729 0.00865051903114187
TF TF:M11972 Factor: rfx5; motif: NYRGCAACSGTTRCYAN 0.0333917566995322 1444 26 7 0.269230769230769 0.00484764542936288
TF TF:M00740 Factor: Rb:E2F-1:DP-1; motif: TTTSGCGC 0.0333917566995322 10427 116 77 0.663793103448276 0.00738467440299223
TF TF:M10683 Factor: HOXB7; motif: GTCRTTAN 0.0337873685814989 1643 4 3 0.75 0.00182592818015825
TF TF:M08213 Factor: Elk-1:TBR2; motif: TNRCACCGGAAGN 0.0337877104870205 6273 116 52 0.448275862068966 0.00828949465965248
TF TF:M01223 Factor: P50:P50; motif: NRGGGAMTNCCCN 0.0337877104870205 1283 111 16 0.144144144144144 0.0124707716289945
TF TF:M02073 Factor: Fli-1; motif: ACCGGAAGYN 0.0337877104870205 5839 28 16 0.571428571428571 0.00274019523891077
TF TF:M11595_1 Factor: GCMa; motif: RTGCGGGTN; match class: 1 0.0337877104870205 5786 56 27 0.482142857142857 0.00466643622537159
TF TF:M11098_1 Factor: Max; motif: NCACGTGNNNNNCACGTGN; match class: 1 0.0338359155994948 628 107 10 0.0934579439252336 0.0159235668789809
TF TF:M07039 Factor: ETF; motif: CCCCGCCCCYN 0.03418044690031 16384 94 88 0.936170212765957 0.00537109375
TF TF:M03895 Factor: CTCF; motif: WGCGCCMYCTAGYGGYN 0.0343089426864406 9251 112 68 0.607142857142857 0.00735055669657334
TF TF:M10098 Factor: DP-1; motif: NRNNGGCGGGAANN 0.0343089426864406 7015 70 37 0.528571428571429 0.0052744119743407
TF TF:M10574 Factor: Gbx2; motif: NYAATTAN 0.0345983796140931 614 59 7 0.11864406779661 0.011400651465798
TF TF:M10573 Factor: Gbx2; motif: NYAATTAN 0.0345983796140931 614 59 7 0.11864406779661 0.011400651465798
TF TF:M04405 Factor: Msx-1; motif: NCAATTAN 0.0345983796140931 614 59 7 0.11864406779661 0.011400651465798
TF TF:M10571 Factor: Gbx2; motif: NYAATTAN 0.0345983796140931 614 59 7 0.11864406779661 0.011400651465798
TF TF:M10860 Factor: En-1; motif: NYAATTAN 0.0345983796140931 614 59 7 0.11864406779661 0.011400651465798
TF TF:M00217 Factor: USF; motif: NCACGTGN 0.0345983796140931 4108 69 25 0.36231884057971 0.0060856864654333
TF TF:M11964_1 Factor: rfx2; motif: NGTTRCCATGGYAACN; match class: 1 0.0345983796140931 163 67 4 0.0597014925373134 0.0245398773006135
TF TF:M05499 Factor: LKLF; motif: NGGGCGG 0.0350822697056063 7900 116 62 0.53448275862069 0.00784810126582279
TF TF:M05386 Factor: KLF17; motif: NGGGCGG 0.0350822697056063 7900 116 62 0.53448275862069 0.00784810126582279
TF TF:M01973 Factor: PLAG1; motif: CCCCCKWNNNGGSCCC 0.0351491985368494 6167 14 10 0.714285714285714 0.0016215339711367
TF TF:M11447_1 Factor: Elf-1; motif: NAMCCGGAAGTN; match class: 1 0.0351491985368494 2593 24 9 0.375 0.00347088314693405
TF TF:M01243_1 Factor: MTF-1; motif: TGCGCAC; match class: 1 0.0354570491312071 731 16 4 0.25 0.00547195622435021
TF TF:M07464 Factor: Prep-1; motif: GRBTGANAGATN 0.0356102864516696 4367 4 4 1 0.000915960613693611
TF TF:M00976_1 Factor: AhR,; motif: NRCGTGNGN; match class: 1 0.0360150483389042 1011 47 8 0.170212765957447 0.00791295746785361
TF TF:M00209_1 Factor: NF-Y; motif: NCTGATTGGYTASY; match class: 1 0.0360150483389042 680 28 5 0.178571428571429 0.00735294117647059
TF TF:M12155_1 Factor: Sp2; motif: NTWAGTCCCGCCCMCTT; match class: 1 0.0360150483389042 1008 104 13 0.125 0.0128968253968254
TF TF:M07354_1 Factor: Egr-1; motif: GCGGGGGCGG; match class: 1 0.0360150483389042 3561 47 17 0.361702127659574 0.0047739399045212
TF TF:M04002 Factor: GCMb; motif: NATGCGGGTN 0.0361883698673678 1282 5 3 0.6 0.00234009360374415
TF TF:M03876_1 Factor: Kaiso; motif: GCMGGGRGCRGS; match class: 1 0.0363085645385993 9106 17 14 0.823529411764706 0.00153744783659126
TF TF:M12273 Factor: YY1; motif: GGCSGCCATTTTGN 0.0363085645385993 6229 73 35 0.479452054794521 0.00561887943490127
TF TF:M12188 Factor: KLF17; motif: NGMCMCRCCCTN 0.0363085645385993 3673 65 22 0.338461538461538 0.00598965423359652
TF TF:M11964 Factor: rfx2; motif: NGTTRCCATGGYAACN 0.0363085645385993 167 67 4 0.0597014925373134 0.0239520958083832
TF TF:M08874 Factor: E2F1; motif: NNNNNGCGSSAAAN 0.0363146522997369 7201 103 52 0.504854368932039 0.00722121927510068
TF TF:M12086 Factor: ZNF501; motif: NNGCGACGCGAACAN 0.0364223187571437 1830 73 15 0.205479452054795 0.00819672131147541
TF TF:M11462 Factor: nerf; motif: AAYSCGGAAGTR 0.0364223187571437 449 42 5 0.119047619047619 0.0111358574610245
TF TF:M00918 Factor: E2F; motif: TTTSGCGSG 0.0364549842562227 5575 13 9 0.692307692307692 0.00161434977578475
TF TF:M00938 Factor: E2F-1; motif: TTGGCGCGRAANNGNM 0.0364549842562227 7334 44 26 0.590909090909091 0.00354513226070357
TF TF:M04097 Factor: RFX3; motif: NGTTRCCATGGYAACN 0.0364850342799507 168 67 4 0.0597014925373134 0.0238095238095238
TF TF:M11451_1 Factor: Elf-1; motif: NANCCGGAAGTN; match class: 1 0.0368289458662482 2112 24 8 0.333333333333333 0.00378787878787879
TF TF:M09901_1 Factor: nerf; motif: NNNCCGGAAGTGN; match class: 1 0.0370379641342979 1363 15 5 0.333333333333333 0.00366837857666911
TF TF:M11755 Factor: HNF-4alpha; motif: RRGGTCAAAGTCCAN 0.0372798694593023 2266 18 7 0.388888888888889 0.0030891438658429
TF TF:M00425_1 Factor: E2F; motif: TTTCGCGC; match class: 1 0.0373930049463089 5355 75 32 0.426666666666667 0.00597572362278245
TF TF:M04196_1 Factor: USF1; motif: RNCACGTGAY; match class: 1 0.0374465552056377 856 33 6 0.181818181818182 0.00700934579439252
TF TF:M08412_1 Factor: rfx3:SREBP-2; motif: ATGGYAACRTCACGTGAY; match class: 1 0.0374637675964858 4386 76 28 0.368421052631579 0.00638394892840857
TF TF:M03922_1 Factor: SP4; motif: NWRGCCACGCCCMCTYN; match class: 1 0.0374637675964858 2143 82 18 0.219512195121951 0.00839944003733084
TF TF:M08759_1 Factor: c-Ets-2; motif: NCCGGAAGTG; match class: 1 0.0374637675964858 2915 26 10 0.384615384615385 0.00343053173241852
TF TF:M00244_1 Factor: NGFI-C; motif: WTGCGTGGGYGG; match class: 1 0.0376978414437879 1772 17 6 0.352941176470588 0.00338600451467269
TF TF:M12163 Factor: KLF3; motif: GRCCRCGCCCN 0.0378956398623745 733 65 8 0.123076923076923 0.0109140518417462
TF TF:M02059_1 Factor: ELK-1; motif: ACCGGAAGTN; match class: 1 0.0385219199794942 3759 38 15 0.394736842105263 0.00399042298483639
TF TF:M03925 Factor: YY2; motif: NCCGCCATNTY 0.0385219199794942 4641 53 22 0.415094339622642 0.00474035768153415
TF TF:M12155 Factor: Sp2; motif: NTWAGTCCCGCCCMCTT 0.0385219199794942 4591 107 38 0.355140186915888 0.00827706382051841
TF TF:M00528 Factor: PPAR; motif: WASNRGGNCAAAGGTCA 0.0386049096064296 4030 113 36 0.31858407079646 0.00893300248138958
TF TF:M04146 Factor: TFAP2A; motif: YGCCCNNRGGCN 0.0387883524657511 6552 105 49 0.466666666666667 0.00747863247863248
TF TF:M07322 Factor: HSF4; motif: CTGCMRN 0.0389346034726917 16573 116 108 0.931034482758621 0.00651662342364086
TF TF:M10632_1 Factor: Nkx2-8; motif: STCGTTGAN; match class: 1 0.0389346034726917 831 58 8 0.137931034482759 0.00962695547533093
TF TF:M11428_1 Factor: PEA3; motif: NACCGGAAGTN; match class: 1 0.0391616694913537 2146 24 8 0.333333333333333 0.00372786579683131
TF TF:M11094 Factor: USF1; motif: NNCACGTGACN 0.0392411359658069 1968 69 15 0.217391304347826 0.00762195121951219
TF TF:M08805 Factor: EAR2; motif: NCTYTGACCTN 0.039246268568068 1027 104 13 0.125 0.0126582278481013
TF TF:M11204 Factor: TCFL4; motif: YNCAYGTGANN 0.0398651908175 1345 45 9 0.2 0.00669144981412639
TF TF:M11397 Factor: Erg; motif: NACCGGATATCCGGTN 0.039918556368067 12005 89 67 0.752808988764045 0.00558100791336943
TF TF:M10529_1 Factor: Sp1; motif: RGGGMGGRGSNGGGG; match class: 1 0.0402509756302313 2816 23 9 0.391304347826087 0.00319602272727273
TF TF:M07617_1 Factor: Sp4; motif: SCCCCKCCCCCSN; match class: 1 0.0402588072590949 901 14 4 0.285714285714286 0.00443951165371809
TF TF:M01200_1 Factor: CTCF; motif: NNNGCCASCAGRKGGCRSNN; match class: 1 0.0402667399577025 554 22 4 0.181818181818182 0.0072202166064982
TF TF:M11430_1 Factor: PEA3; motif: NACCGGAAGTN; match class: 1 0.0405627727943361 4902 63 26 0.412698412698413 0.00530395756833945
TF TF:M11448 Factor: Elf-1; motif: NANGCGGAAGTN 0.0406278232917137 7600 35 22 0.628571428571429 0.00289473684210526
TF TF:M02281 Factor: SP1; motif: CCCCKCCCCC 0.0407719795859902 6480 109 50 0.458715596330275 0.00771604938271605
TF TF:M11090 Factor: TFEA; motif: YRCACGTGACN 0.0407719795859902 6189 69 33 0.478260869565217 0.00533204071740184
TF TF:M08390_1 Factor: A-Myb:Elf-1; motif: NMCCGGAACCGTTA; match class: 1 0.0407719795859902 4784 87 33 0.379310344827586 0.00689799331103679
TF TF:M12313 Factor: ZNF460; motif: NNACNCCCCCCNN 0.0407719795859902 5825 24 14 0.583333333333333 0.00240343347639485
TF TF:M00919 Factor: E2F; motif: NCSCGCSAAAN 0.040970351026874 6149 23 14 0.608695652173913 0.00227679297446739
TF TF:M09877 Factor: BMAL1; motif: NSCACGTGNSN 0.041027877870133 2189 69 16 0.231884057971014 0.00730927364093193
TF TF:M01714_1 Factor: KLF15; motif: GAGNNGGGGNGTDG; match class: 1 0.0414598962716172 209 28 3 0.107142857142857 0.0143540669856459
TF TF:M11389 Factor: elf5; motif: GAMCCGGAAGTN 0.0417428223106311 1308 23 6 0.260869565217391 0.00458715596330275
TF TF:M04194 Factor: TFEB; motif: RNCACGTGAC 0.0417624827366654 1436 59 11 0.186440677966102 0.00766016713091922
TF TF:M01854 Factor: AML2; motif: CCRCACCAYDN 0.0422333035540352 2791 41 13 0.317073170731707 0.00465782873522035
TF TF:M00139_1 Factor: AhR; motif: CCYCNRRSTNGCGTGASA; match class: 1 0.0422903960955785 437 14 3 0.214285714285714 0.0068649885583524
TF TF:M04743 Factor: c-Myc; motif: NSCACGTGGN 0.0422903960955785 4819 77 30 0.38961038961039 0.00622535795808259
TF TF:M10625_1 Factor: Nkx3-2; motif: NTCGTTAN; match class: 1 0.0422903960955785 1314 23 6 0.260869565217391 0.0045662100456621
TF TF:M07353_1 Factor: E2A; motif: CAGNTGNN; match class: 1 0.0422903960955785 263 108 6 0.0555555555555556 0.0228136882129278
TF TF:M11788 Factor: Rev-ErbAalpha; motif: NAWNTRGGTYAGTRGGTCRN 0.0427363274428676 1579 78 14 0.179487179487179 0.00886637112096264
TF TF:M03920_1 Factor: SP1; motif: RCCMCRCCCMC; match class: 1 0.0428778996285417 3020 104 27 0.259615384615385 0.00894039735099338
TF TF:M11033_1 Factor: Six-2; motif: NCGTATCRYN; match class: 1 0.043251152429773 2382 32 10 0.3125 0.00419815281276238
TF TF:M04797_1 Factor: Egr-1; motif: CCGCCCMCG; match class: 1 0.0434972913563684 1565 14 5 0.357142857142857 0.00319488817891374
TF TF:M07302_1 Factor: NF-Y; motif: RGCCAATCRGN; match class: 1 0.0438194555715944 184 108 5 0.0462962962962963 0.0271739130434783
TF TF:M09760 Factor: DPF2; motif: NYCACYTCCYCNYYCY 0.0440594852175182 8179 24 17 0.708333333333333 0.00207849370338672
TF TF:M09904_1 Factor: Elk-1; motif: RCCGGAAGTGN; match class: 1 0.0440656792555669 2743 24 9 0.375 0.003281079110463
TF TF:M03976 Factor: ERG; motif: ACCGGAWATCCGGT 0.0441172156100639 12803 89 70 0.786516853932584 0.00546746856205577
TF TF:M10426 Factor: ctcf; motif: CCRSCAGGGGGCGCN 0.0442295693258072 9305 111 67 0.603603603603604 0.00720042987641053
TF TF:M03806 Factor: ZBTB7C; motif: GKCCCGGGCKG 0.044271248457518 3031 114 29 0.254385964912281 0.00956779940613659
TF TF:M08223_1 Factor: Elk-1:OC-2; motif: RCCGGAASCGATCGATNN; match class: 1 0.0452387152557427 5853 44 22 0.5 0.00375875619340509
TF TF:M11396 Factor: Erg; motif: NACCGGAARTN 0.045558989364206 10765 116 78 0.672413793103448 0.00724570366929865
TF TF:M08455 Factor: ERF:T-bet; motif: TMACACCGGAAR 0.0456752516422039 374 104 7 0.0673076923076923 0.018716577540107
TF TF:M11081 Factor: SREBP-1; motif: RTCRCGTGAY 0.0463920274856238 11062 69 50 0.72463768115942 0.00451997830410414
TF TF:M01078 Factor: c-Ets-1; motif: NNNRCCGGAWRYNNNN 0.0464207510361821 7544 116 59 0.508620689655172 0.00782078472958643
TF TF:M03821 Factor: ER-beta; motif: ANNSTGACCYRGNN 0.0464207510361821 6456 5 5 1 0.000774473358116481
TF TF:M00634 Factor: GCM; motif: CNNRCCCGCATD 0.0465039120481312 2152 7 4 0.571428571428571 0.00185873605947955
TF TF:M11877_1 Factor: pax-2; motif: NCGTCACGCNYSRNYGCNYN; match class: 1 0.0466997542991213 5304 37 18 0.486486486486487 0.00339366515837104
TF TF:M11491 Factor: LBP9; motif: ACYRGTTNNAACYRGT 0.0467462425284959 5146 38 18 0.473684210526316 0.00349786241741158
TF TF:M08470 Factor: Fli-1:Dlx-2; motif: RNCGGAARYAATTA 0.0467462425284959 5930 7 6 0.857142857142857 0.00101180438448567
TF TF:M11058 Factor: Hey1; motif: NGCRCGYGYN 0.0467462425284959 13162 116 91 0.78448275862069 0.00691384288102112
TF TF:M07406 Factor: SREBP-2; motif: RTGGGGTGAY 0.0467462425284959 5983 88 39 0.443181818181818 0.00651846899548721
TF TF:M00916_1 Factor: CREB; motif: NNTKACGTCANNNS; match class: 1 0.0471826660602139 1692 98 17 0.173469387755102 0.0100472813238771
TF TF:M11437 Factor: SAP-1; motif: NRCCGGAWGYN 0.0472942130328836 2788 24 9 0.375 0.00322812051649928
TF TF:M09764_1 Factor: ROX; motif: GNNNCASGTGGS; match class: 1 0.0473482210637228 1631 69 13 0.188405797101449 0.00797057020232986
TF TF:M03893_1 Factor: WT1; motif: GNGGGGGCGGGG; match class: 1 0.0488023194262504 3980 24 11 0.458333333333333 0.00276381909547739
TF TF:M07365 Factor: NFATc2; motif: GGAAAANNNN 0.0488586401326862 111 115 4 0.0347826086956522 0.036036036036036
TF TF:M11482 Factor: AP-2gamma; motif: NSCCYNNRGSN 0.0489050387920336 6696 112 52 0.464285714285714 0.00776583034647551
TF TF:M01243 Factor: MTF-1; motif: TGCGCAC 0.0494037882092826 2835 112 27 0.241071428571429 0.00952380952380952
TF TF:M03914 Factor: KLF16; motif: GMCACGCCCCC 0.0494037882092826 3363 109 30 0.275229357798165 0.00892060660124889
TF TF:M11052 Factor: Hey2; motif: NNCACGYGNN 0.049922378817219 12502 60 48 0.8 0.00383938569828827
WP WP:WP4718 Cholesterol metabolism (includes both Bloch and Kandutsch-Russell pathways) 2.68245860422364e-32 47 115 25 0.217391304347826 0.531914893617021
WP WP:WP197 Cholesterol Biosynthesis Pathway 3.39047334955303e-24 15 67 13 0.194029850746269 0.866666666666667
WP WP:WP1982 Sterol Regulatory Element-Binding Proteins (SREBP) signalling 1.15758735879038e-14 73 115 17 0.147826086956522 0.232876712328767
WP WP:WP3963 Mevalonate pathway 7.38231965104556e-11 7 67 6 0.0895522388059701 0.857142857142857
WP WP:WP4724 Omega-9 FA synthesis 3.69308451483705e-10 16 109 8 0.073394495412844 0.5
WP WP:WP4804 Cholesterol Biosynthesis with Skeletal Dysplasias 1.38003582312458e-09 7 115 6 0.0521739130434783 0.857142857142857
WP WP:WP357 Fatty Acid Biosynthesis 2.95233879185699e-06 22 93 6 0.0645161290322581 0.272727272727273
WP WP:WP2011 SREBF and miR33 in cholesterol and lipid homeostasis 9.00792692420282e-06 19 29 4 0.137931034482759 0.210526315789474
WP WP:WP3613 Photodynamic therapy-induced unfolded protein response 1.33391608916237e-05 29 50 5 0.1 0.172413793103448
WP WP:WP4723 Omega-3/Omega-6 FA synthesis 0.00017765585999732 15 84 4 0.0476190476190476 0.266666666666667
WP WP:WP430 Statin Pathway 0.000547503417875344 33 18 3 0.166666666666667 0.0909090909090909
WP WP:WP4290 Metabolic reprogramming in colon cancer 0.000651035630193285 44 77 5 0.0649350649350649 0.113636363636364
WP WP:WP4545 Oxysterols derived from cholesterol 0.000886423322561721 46 16 3 0.1875 0.0652173913043478
WP WP:WP3995 Prion disease pathway 0.0197283056273127 37 61 3 0.0491803278688525 0.0810810810810811
WP WP:WP3942 PPAR signaling pathway 0.0284100319823109 67 80 4 0.05 0.0597014925373134
WP WP:WP3965 Lipid Metabolism Pathway 0.0284100319823109 29 93 3 0.032258064516129 0.103448275862069
WP WP:WP4313 Ferroptosis 0.0400123114804558 40 80 3 0.0375 0.075

pEpi04 transcription factor target enrichment of top program genes

TF enrichment of pEpi04
Possible regulators of activation of pEpi04 in epithelial cells. (Left) pearson correlation of TF expression and gene expression program activatity in Epithelial cells, (right) negative log p-value for enrichment of TF binding sites among top uniqueness weighted genes for the gene program. Blue bars indicate significant TFs meeting the following criteria: FDR<0.1, overlap > 2, Corr. R > 0, permutation based p-value < 0.05.