pP04 program activity among Plasma cells

Activation of pP04
pP04 gene program activation in Plasma cells.
Gene program activation of pP04 by different cell subtypes
pP04 gene program activation among cells of different subtypes (Plasma cells).

pP04 top program genes

Top genes of pP04 program
Bar plots showing the top genes for each gene program, ranked by (left) unique weights, (right) raw weights.

pP04 gene-set enrichment of top program genes (using g-profiler)

GSEA wth gene profiler of pP04
pP04 gene-set enrichment summary using g-profiler webtool.
Source termID Name Padj Tsize Qsize Overlap Precision Recall
CORUM CORUM:742 eIF3 complex (EIF3S6, EIF3S5, EIF3S4, EIF3S3, EIF3S6IP, EIF3S2, EIF3S9, EIF3S12, EIF3S10, EIF3S8, EIF3S1, EIF3S7) 0.00188208806126765 12 108 5 0.0462962962962963 0.416666666666667
CORUM CORUM:1097 eIF3 complex (EIF3S6, EIF3S5, EIF3S4, EIF3S3, EIF3S6IP, EIF3S2, EIF3S9, EIF3S12, EIF3S10, EIF3S8, EIF3S1, EIF3S7, PCID1) 0.00199076975460329 13 108 5 0.0462962962962963 0.384615384615385
GO:BP GO:0006955 immune response 8.01985165686993e-17 2311 140 62 0.442857142857143 0.0268282128948507
GO:BP GO:0002376 immune system process 1.23982947879457e-14 3278 140 70 0.5 0.0213544844417328
GO:BP GO:0001775 cell activation 1.51029612157742e-14 1495 140 47 0.335714285714286 0.031438127090301
GO:BP GO:0002443 leukocyte mediated immunity 5.30373734114588e-14 877 140 36 0.257142857142857 0.0410490307867731
GO:BP GO:0002252 immune effector process 6.99986938143955e-14 1309 140 43 0.307142857142857 0.0328495034377387
GO:BP GO:0002366 leukocyte activation involved in immune response 2.48605211386382e-13 717 140 32 0.228571428571429 0.0446304044630404
GO:BP GO:0002263 cell activation involved in immune response 2.49555321616424e-13 721 140 32 0.228571428571429 0.0443828016643551
GO:BP GO:0045321 leukocyte activation 4.7039679218133e-13 1332 140 42 0.3 0.0315315315315315
GO:BP GO:0043299 leukocyte degranulation 2.37412466697292e-12 535 140 27 0.192857142857143 0.0504672897196262
GO:BP GO:0019882 antigen processing and presentation 4.07506425681663e-12 234 136 19 0.139705882352941 0.0811965811965812
GO:BP GO:0034341 response to interferon-gamma 7.17878361856352e-12 196 11 8 0.727272727272727 0.0408163265306122
GO:BP GO:0019883 antigen processing and presentation of endogenous antigen 7.17878361856352e-12 26 111 9 0.0810810810810811 0.346153846153846
GO:BP GO:0045055 regulated exocytosis 9.94594222605984e-12 785 140 31 0.221428571428571 0.0394904458598726
GO:BP GO:0050776 regulation of immune response 1.46051509562899e-11 996 137 34 0.248175182481752 0.034136546184739
GO:BP GO:0002684 positive regulation of immune system process 1.63865461800324e-11 1065 137 35 0.255474452554745 0.0328638497652582
GO:BP GO:0048002 antigen processing and presentation of peptide antigen 1.66328927535798e-11 192 136 17 0.125 0.0885416666666667
GO:BP GO:0002444 myeloid leukocyte mediated immunity 1.90790691484645e-11 551 140 26 0.185714285714286 0.0471869328493648
GO:BP GO:0002483 antigen processing and presentation of endogenous peptide antigen 1.90790691484645e-11 19 111 8 0.0720720720720721 0.421052631578947
GO:BP GO:0002682 regulation of immune system process 1.90790691484645e-11 1617 111 38 0.342342342342342 0.0235003092145949
GO:BP GO:0071346 cellular response to interferon-gamma 3.95142389489296e-11 175 9 7 0.777777777777778 0.04
GO:BP GO:0002478 antigen processing and presentation of exogenous peptide antigen 3.95142389489296e-11 174 136 16 0.117647058823529 0.0919540229885057
GO:BP GO:0016192 vesicle-mediated transport 4.49352017785752e-11 2180 140 50 0.357142857142857 0.0229357798165138
GO:BP GO:0043312 neutrophil degranulation 4.73683769604186e-11 482 140 24 0.171428571428571 0.0497925311203319
GO:BP GO:0002283 neutrophil activation involved in immune response 5.18879216153073e-11 485 140 24 0.171428571428571 0.0494845360824742
GO:BP GO:0019884 antigen processing and presentation of exogenous antigen 6.69148063324272e-11 182 136 16 0.117647058823529 0.0879120879120879
GO:BP GO:0002275 myeloid cell activation involved in immune response 7.96082054012202e-11 547 140 25 0.178571428571429 0.0457038391224863
GO:BP GO:0002446 neutrophil mediated immunity 7.96082054012202e-11 497 140 24 0.171428571428571 0.0482897384305835
GO:BP GO:0042119 neutrophil activation 7.96082054012202e-11 498 140 24 0.171428571428571 0.0481927710843374
GO:BP GO:0036230 granulocyte activation 9.79640838324171e-11 504 140 24 0.171428571428571 0.0476190476190476
GO:BP GO:0006887 exocytosis 1.74028040144183e-10 904 140 31 0.221428571428571 0.0342920353982301
GO:BP GO:0044419 biological process involved in interspecies interaction between organisms 1.74028040144183e-10 2255 115 44 0.382608695652174 0.0195121951219512
GO:BP GO:0002480 antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent 2.02577114141148e-10 8 9 4 0.444444444444444 0.5
GO:BP GO:0002486 antigen processing and presentation of endogenous peptide antigen via MHC class I via ER pathway, TAP-independent 3.91914123282796e-10 3 4 3 0.75 1
GO:BP GO:0002484 antigen processing and presentation of endogenous peptide antigen via MHC class I via ER pathway 3.91914123282796e-10 3 4 3 0.75 1
GO:BP GO:0051641 cellular localization 5.74153311597998e-10 3541 140 63 0.45 0.0177915842982208
GO:BP GO:0002764 immune response-regulating signaling pathway 5.78350461717001e-10 515 137 23 0.167883211678832 0.0446601941747573
GO:BP GO:0051649 establishment of localization in cell 7.01873549022956e-10 2813 140 55 0.392857142857143 0.019552079630288
GO:BP GO:0002274 myeloid leukocyte activation 7.05777817174165e-10 667 140 26 0.185714285714286 0.0389805097451274
GO:BP GO:0002757 immune response-activating signal transduction 8.41743682083727e-10 477 137 22 0.160583941605839 0.0461215932914046
GO:BP GO:0002429 immune response-activating cell surface receptor signaling pathway 8.41743682083727e-10 477 137 22 0.160583941605839 0.0461215932914046
GO:BP GO:0050778 positive regulation of immune response 9.80993953842711e-10 753 137 27 0.197080291970803 0.0358565737051793
GO:BP GO:0098609 cell-cell adhesion 1.63845782787222e-09 894 111 26 0.234234234234234 0.029082774049217
GO:BP GO:0007159 leukocyte cell-cell adhesion 1.82293236258007e-09 375 130 19 0.146153846153846 0.0506666666666667
GO:BP GO:0032940 secretion by cell 2.81301838411656e-09 1364 140 36 0.257142857142857 0.0263929618768328
GO:BP GO:0002768 immune response-regulating cell surface receptor signaling pathway 2.95745161030363e-09 512 137 22 0.160583941605839 0.04296875
GO:BP GO:0002253 activation of immune response 3.25273424664827e-09 568 137 23 0.167883211678832 0.0404929577464789
GO:BP GO:0001909 leukocyte mediated cytotoxicity 3.66895132866629e-09 107 111 11 0.0990990990990991 0.102803738317757
GO:BP GO:0071345 cellular response to cytokine stimulus 3.95519769702728e-09 1132 137 32 0.233576642335766 0.0282685512367491
GO:BP GO:0044403 biological process involved in symbiotic interaction 4.25391053756688e-09 1001 137 30 0.218978102189781 0.02997002997003
GO:BP GO:0016032 viral process 4.80059300905859e-09 942 137 29 0.211678832116788 0.0307855626326964
GO:BP GO:0006810 transport 4.80059300905859e-09 5224 140 77 0.55 0.014739663093415
GO:BP GO:0034097 response to cytokine 6.19647728799766e-09 1226 137 33 0.240875912408759 0.0269168026101142
GO:BP GO:0140352 export from cell 6.95495382246359e-09 1418 140 36 0.257142857142857 0.0253878702397743
GO:BP GO:0046903 secretion 8.10859796841507e-09 1501 140 37 0.264285714285714 0.0246502331778814
GO:BP GO:0060333 interferon-gamma-mediated signaling pathway 8.96775907812192e-09 88 111 10 0.0900900900900901 0.113636363636364
GO:BP GO:0001913 T cell mediated cytotoxicity 8.99672362051296e-09 42 111 8 0.0720720720720721 0.19047619047619
GO:BP GO:0001916 positive regulation of T cell mediated cytotoxicity 9.26089986024012e-09 26 111 7 0.0630630630630631 0.269230769230769
GO:BP GO:0046649 lymphocyte activation 1.14436842131803e-08 771 130 25 0.192307692307692 0.0324254215304799
GO:BP GO:0051234 establishment of localization 1.76863501483662e-08 5372 140 77 0.55 0.0143335815338794
GO:BP GO:0050852 T cell receptor signaling pathway 2.43921875712874e-08 203 137 14 0.102189781021898 0.0689655172413793
GO:BP GO:0001906 cell killing 4.206543291091e-08 175 111 12 0.108108108108108 0.0685714285714286
GO:BP GO:0051249 regulation of lymphocyte activation 4.46978225977088e-08 518 130 20 0.153846153846154 0.0386100386100386
GO:BP GO:0002250 adaptive immune response 5.48547618707828e-08 689 111 21 0.189189189189189 0.0304789550072569
GO:BP GO:0019885 antigen processing and presentation of endogenous peptide antigen via MHC class I 5.95217972321051e-08 13 4 3 0.75 0.230769230769231
GO:BP GO:0045087 innate immune response 6.29249756679053e-08 998 111 25 0.225225225225225 0.0250501002004008
GO:BP GO:0001914 regulation of T cell mediated cytotoxicity 7.81405037032915e-08 35 111 7 0.0630630630630631 0.2
GO:BP GO:0002711 positive regulation of T cell mediated immunity 8.22406414337719e-08 48 130 8 0.0615384615384615 0.166666666666667
GO:BP GO:0042270 protection from natural killer cell mediated cytotoxicity 8.22406414337719e-08 6 9 3 0.333333333333333 0.5
GO:BP GO:0019221 cytokine-mediated signaling pathway 8.47071181972213e-08 810 137 25 0.182481751824818 0.0308641975308642
GO:BP GO:1903039 positive regulation of leukocyte cell-cell adhesion 9.70842868639555e-08 241 130 14 0.107692307692308 0.0580912863070539
GO:BP GO:0042110 T cell activation 9.70842868639555e-08 489 130 19 0.146153846153846 0.0388548057259714
GO:BP GO:0050863 regulation of T cell activation 1.17940042982498e-07 337 130 16 0.123076923076923 0.0474777448071217
GO:BP GO:1903037 regulation of leukocyte cell-cell adhesion 1.21373990281928e-07 338 130 16 0.123076923076923 0.0473372781065089
GO:BP GO:0007155 cell adhesion 1.3302897780793e-07 1492 39 17 0.435897435897436 0.0113941018766756
GO:BP GO:0050851 antigen receptor-mediated signaling pathway 1.33798876085019e-07 323 137 16 0.116788321167883 0.0495356037151703
GO:BP GO:0002474 antigen processing and presentation of peptide antigen via MHC class I 1.35167668267534e-07 99 134 10 0.0746268656716418 0.101010101010101
GO:BP GO:0022610 biological adhesion 1.37300348464548e-07 1499 39 17 0.435897435897436 0.0113408939292862
GO:BP GO:0002479 antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent 1.77738709637739e-07 75 134 9 0.0671641791044776 0.12
GO:BP GO:0050870 positive regulation of T cell activation 2.59372380752814e-07 219 130 13 0.1 0.0593607305936073
GO:BP GO:0048584 positive regulation of response to stimulus 2.70429329364957e-07 2344 111 38 0.342342342342342 0.0162116040955631
GO:BP GO:0042590 antigen processing and presentation of exogenous peptide antigen via MHC class I 3.06337249153307e-07 80 134 9 0.0671641791044776 0.1125
GO:BP GO:0051251 positive regulation of lymphocyte activation 3.22860928979739e-07 365 130 16 0.123076923076923 0.0438356164383562
GO:BP GO:0050670 regulation of lymphocyte proliferation 3.23297795385992e-07 230 104 12 0.115384615384615 0.0521739130434783
GO:BP GO:0032944 regulation of mononuclear cell proliferation 3.51991502753122e-07 232 104 12 0.115384615384615 0.0517241379310345
GO:BP GO:0002694 regulation of leukocyte activation 5.21241240654456e-07 610 130 20 0.153846153846154 0.0327868852459016
GO:BP GO:0046651 lymphocyte proliferation 5.21241240654456e-07 294 104 13 0.125 0.0442176870748299
GO:BP GO:0032943 mononuclear cell proliferation 5.74687873199295e-07 297 104 13 0.125 0.0437710437710438
GO:BP GO:0098542 defense response to other organism 5.74687873199295e-07 1218 111 26 0.234234234234234 0.0213464696223317
GO:BP GO:0030155 regulation of cell adhesion 6.20212558557882e-07 748 130 22 0.169230769230769 0.0294117647058824
GO:BP GO:0022409 positive regulation of cell-cell adhesion 6.20212558557882e-07 284 130 14 0.107692307692308 0.0492957746478873
GO:BP GO:0022407 regulation of cell-cell adhesion 7.36855900411783e-07 445 130 17 0.130769230769231 0.0382022471910112
GO:BP GO:0070663 regulation of leukocyte proliferation 7.72558894304912e-07 251 104 12 0.115384615384615 0.047808764940239
GO:BP GO:0001912 positive regulation of leukocyte mediated cytotoxicity 8.80438701448815e-07 51 111 7 0.0630630630630631 0.137254901960784
GO:BP GO:0042267 natural killer cell mediated cytotoxicity 8.80438701448815e-07 62 91 7 0.0769230769230769 0.112903225806452
GO:BP GO:0001732 formation of cytoplasmic translation initiation complex 9.87792556787967e-07 16 108 5 0.0462962962962963 0.3125
GO:BP GO:0070887 cellular response to chemical stimulus 1.04012600022705e-06 3393 140 54 0.385714285714286 0.0159151193633952
GO:BP GO:0002228 natural killer cell mediated immunity 1.16907227132382e-06 65 91 7 0.0769230769230769 0.107692307692308
GO:BP GO:0002456 T cell mediated immunity 1.16907227132382e-06 98 130 9 0.0692307692307692 0.0918367346938776
GO:BP GO:0002449 lymphocyte mediated immunity 1.16907227132382e-06 354 111 14 0.126126126126126 0.0395480225988701
GO:BP GO:0002696 positive regulation of leukocyte activation 1.43465527418979e-06 412 130 16 0.123076923076923 0.0388349514563107
GO:BP GO:0050865 regulation of cell activation 1.43465527418979e-06 655 130 20 0.153846153846154 0.0305343511450382
GO:BP GO:0070661 leukocyte proliferation 1.43465527418979e-06 325 104 13 0.125 0.04
GO:BP GO:0051179 localization 1.44132809421469e-06 6901 140 85 0.607142857142857 0.012317055499203
GO:BP GO:0071310 cellular response to organic substance 1.46162538990732e-06 2776 9 9 1 0.00324207492795389
GO:BP GO:0045953 negative regulation of natural killer cell mediated cytotoxicity 1.48759555970011e-06 16 9 3 0.333333333333333 0.1875
GO:BP GO:0002709 regulation of T cell mediated immunity 1.73964493824607e-06 74 130 8 0.0615384615384615 0.108108108108108
GO:BP GO:0002716 negative regulation of natural killer cell mediated immunity 1.73964493824607e-06 17 9 3 0.333333333333333 0.176470588235294
GO:BP GO:0042129 regulation of T cell proliferation 1.73964493824607e-06 176 130 11 0.0846153846153846 0.0625
GO:BP GO:0051049 regulation of transport 1.73964493824607e-06 1809 104 30 0.288461538461538 0.0165837479270315
GO:BP GO:0050867 positive regulation of cell activation 1.94548316254748e-06 424 130 16 0.123076923076923 0.0377358490566038
GO:BP GO:0048583 regulation of response to stimulus 2.03348024450444e-06 4278 111 52 0.468468468468468 0.0121552127162225
GO:BP GO:0031343 positive regulation of cell killing 2.07036742844739e-06 59 111 7 0.0630630630630631 0.11864406779661
GO:BP GO:0001911 negative regulation of leukocyte mediated cytotoxicity 2.39269814629246e-06 20 104 5 0.0480769230769231 0.25
GO:BP GO:0060337 type I interferon signaling pathway 2.53681679045215e-06 95 9 4 0.444444444444444 0.0421052631578947
GO:BP GO:0071357 cellular response to type I interferon 2.62351335804767e-06 96 9 4 0.444444444444444 0.0416666666666667
GO:BP GO:0009607 response to biotic stimulus 2.80484855766029e-06 1626 111 29 0.261261261261261 0.0178351783517835
GO:BP GO:0034340 response to type I interferon 3.16585490741153e-06 101 9 4 0.444444444444444 0.0396039603960396
GO:BP GO:0010033 response to organic substance 3.37034980744196e-06 3412 137 52 0.37956204379562 0.0152403282532239
GO:BP GO:0002707 negative regulation of lymphocyte mediated immunity 4.40362709399138e-06 43 104 6 0.0576923076923077 0.13953488372093
GO:BP GO:0031342 negative regulation of cell killing 4.69517500725667e-06 24 9 3 0.333333333333333 0.125
GO:BP GO:0002698 negative regulation of immune effector process 5.64196652105935e-06 125 125 9 0.072 0.072
GO:BP GO:0051707 response to other organism 6.30388488861788e-06 1592 111 28 0.252252252252252 0.0175879396984925
GO:BP GO:0043207 response to external biotic stimulus 6.41660366354842e-06 1594 111 28 0.252252252252252 0.0175658720200753
GO:BP GO:0042098 T cell proliferation 7.11587125199695e-06 205 130 11 0.0846153846153846 0.0536585365853659
GO:BP GO:0006952 defense response 8.06708986149915e-06 1818 111 30 0.27027027027027 0.0165016501650165
GO:BP GO:0002819 regulation of adaptive immune response 8.97619015863136e-06 167 130 10 0.0769230769230769 0.0598802395209581
GO:BP GO:0001910 regulation of leukocyte mediated cytotoxicity 8.97619015863136e-06 74 111 7 0.0630630630630631 0.0945945945945946
GO:BP GO:0002460 adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains 8.97619015863136e-06 363 111 13 0.117117117117117 0.0358126721763085
GO:BP GO:0070527 platelet aggregation 1.0682943376875e-05 64 18 4 0.222222222222222 0.0625
GO:BP GO:0002699 positive regulation of immune effector process 1.09289390814091e-05 215 130 11 0.0846153846153846 0.0511627906976744
GO:BP GO:0002824 positive regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains 1.11374475442355e-05 96 130 8 0.0615384615384615 0.0833333333333333
GO:BP GO:0002704 negative regulation of leukocyte mediated immunity 1.13002628813313e-05 51 104 6 0.0576923076923077 0.117647058823529
GO:BP GO:1903708 positive regulation of hemopoiesis 1.28308820027151e-05 157 111 9 0.0810810810810811 0.0573248407643312
GO:BP GO:1902107 positive regulation of leukocyte differentiation 1.28308820027151e-05 157 111 9 0.0810810810810811 0.0573248407643312
GO:BP GO:0045785 positive regulation of cell adhesion 1.39732565579344e-05 437 130 15 0.115384615384615 0.034324942791762
GO:BP GO:0051240 positive regulation of multicellular organismal process 1.41944062424467e-05 1455 133 29 0.218045112781955 0.0199312714776632
GO:BP GO:0042221 response to chemical 1.48865744226766e-05 4781 140 64 0.457142857142857 0.013386320853378
GO:BP GO:0002821 positive regulation of adaptive immune response 1.55254440630361e-05 101 130 8 0.0615384615384615 0.0792079207920792
GO:BP GO:0001817 regulation of cytokine production 1.64513943736075e-05 806 104 18 0.173076923076923 0.0223325062034739
GO:BP GO:0034109 homotypic cell-cell adhesion 1.67838312272249e-05 87 105 7 0.0666666666666667 0.0804597701149425
GO:BP GO:0002708 positive regulation of lymphocyte mediated immunity 1.90245724138856e-05 104 130 8 0.0615384615384615 0.0769230769230769
GO:BP GO:0002683 negative regulation of immune system process 1.92375507782496e-05 420 104 13 0.125 0.030952380952381
GO:BP GO:0042269 regulation of natural killer cell mediated cytotoxicity 2.03786726887775e-05 41 9 3 0.333333333333333 0.0731707317073171
GO:BP GO:0002181 cytoplasmic translation 2.04394423158251e-05 103 133 8 0.0601503759398496 0.0776699029126214
GO:BP GO:0002504 antigen processing and presentation of peptide or polysaccharide antigen via MHC class II 2.38556257727785e-05 103 136 8 0.0588235294117647 0.0776699029126214
GO:BP GO:0043269 regulation of ion transport 2.38556257727785e-05 1379 99 23 0.232323232323232 0.0166787527193619
GO:BP GO:0007165 signal transduction 2.41778003006324e-05 6309 13 13 1 0.00206054842288794
GO:BP GO:0050671 positive regulation of lymphocyte proliferation 2.43098807043876e-05 141 11 4 0.363636363636364 0.0283687943262411
GO:BP GO:0002697 regulation of immune effector process 2.4429688654155e-05 461 130 15 0.115384615384615 0.0325379609544469
GO:BP GO:0010628 positive regulation of gene expression 2.4519601658437e-05 1160 11 7 0.636363636363636 0.00603448275862069
GO:BP GO:0032946 positive regulation of mononuclear cell proliferation 2.4519601658437e-05 142 11 4 0.363636363636364 0.028169014084507
GO:BP GO:0002715 regulation of natural killer cell mediated immunity 2.53515958921681e-05 45 9 3 0.333333333333333 0.0666666666666667
GO:BP GO:0002700 regulation of production of molecular mediator of immune response 2.82384719629044e-05 148 11 4 0.363636363636364 0.027027027027027
GO:BP GO:0001816 cytokine production 2.82384719629044e-05 844 104 18 0.173076923076923 0.0213270142180095
GO:BP GO:0002706 regulation of lymphocyte mediated immunity 2.96288938283317e-05 151 130 9 0.0692307692307692 0.0596026490066225
GO:BP GO:0002822 regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains 3.11090237317454e-05 152 130 9 0.0692307692307692 0.0592105263157895
GO:BP GO:0065008 regulation of biological quality 3.17804774319662e-05 4131 140 57 0.407142857142857 0.0137981118373275
GO:BP GO:1902105 regulation of leukocyte differentiation 3.19357312927894e-05 288 111 11 0.0990990990990991 0.0381944444444444
GO:BP GO:0070665 positive regulation of leukocyte proliferation 3.287225858796e-05 155 11 4 0.363636363636364 0.0258064516129032
GO:BP GO:0031341 regulation of cell killing 3.3096604063473e-05 93 111 7 0.0630630630630631 0.0752688172043011
GO:BP GO:0006950 response to stress 3.58176123422935e-05 4170 9 9 1 0.00215827338129496
GO:BP GO:0002183 cytoplasmic translational initiation 3.81641066393904e-05 35 108 5 0.0462962962962963 0.142857142857143
GO:BP GO:0002521 leukocyte differentiation 4.09513482452489e-05 550 130 16 0.123076923076923 0.0290909090909091
GO:BP GO:0048518 positive regulation of biological process 4.12536892087145e-05 6363 115 65 0.565217391304348 0.0102153072450102
GO:BP GO:0002703 regulation of leukocyte mediated immunity 4.39593328716954e-05 205 130 10 0.0769230769230769 0.0487804878048781
GO:BP GO:0002720 positive regulation of cytokine production involved in immune response 4.57005324650579e-05 54 130 6 0.0461538461538462 0.111111111111111
GO:BP GO:0007154 cell communication 4.72922952770781e-05 6829 44 32 0.727272727272727 0.004685898374579
GO:BP GO:0002705 positive regulation of leukocyte mediated immunity 5.2411271544934e-05 122 130 8 0.0615384615384615 0.0655737704918033
GO:BP GO:0080134 regulation of response to stress 5.32046970965643e-05 1443 93 22 0.236559139784946 0.0152460152460152
GO:BP GO:0023052 signaling 5.60132934898497e-05 6810 13 13 1 0.00190895741556535
GO:BP GO:0002763 positive regulation of myeloid leukocyte differentiation 6.34669757675479e-05 59 71 5 0.0704225352112676 0.0847457627118644
GO:BP GO:0050777 negative regulation of immune response 6.34669757675479e-05 157 104 8 0.0769230769230769 0.0509554140127389
GO:BP GO:0002440 production of molecular mediator of immune response 6.63120776252817e-05 189 11 4 0.363636363636364 0.0211640211640212
GO:BP GO:0006909 phagocytosis 6.69811710044258e-05 387 128 13 0.1015625 0.0335917312661499
GO:BP GO:0045824 negative regulation of innate immune response 6.9629950289742e-05 66 9 3 0.333333333333333 0.0454545454545455
GO:BP GO:0032879 regulation of localization 6.9629950289742e-05 2872 115 38 0.330434782608696 0.0132311977715877
GO:BP GO:0032956 regulation of actin cytoskeleton organization 7.02032571000297e-05 366 136 13 0.0955882352941176 0.0355191256830601
GO:BP GO:0007166 cell surface receptor signaling pathway 9.15306809424515e-05 3210 13 10 0.769230769230769 0.00311526479750779
GO:BP GO:0050860 negative regulation of T cell receptor signaling pathway 0.000107685746779914 23 96 4 0.0416666666666667 0.173913043478261
GO:BP GO:0000165 MAPK cascade 0.000125484126550411 935 137 21 0.153284671532847 0.0224598930481283
GO:BP GO:0002396 MHC protein complex assembly 0.000133000384740065 7 111 3 0.027027027027027 0.428571428571429
GO:BP GO:0002702 positive regulation of production of molecular mediator of immune response 0.000133000384740065 100 130 7 0.0538461538461538 0.07
GO:BP GO:0019886 antigen processing and presentation of exogenous peptide antigen via MHC class II 0.000134831489787234 96 136 7 0.0514705882352941 0.0729166666666667
GO:BP GO:0046635 positive regulation of alpha-beta T cell activation 0.000143492650225311 67 130 6 0.0461538461538462 0.0895522388059701
GO:BP GO:0051050 positive regulation of transport 0.000154871508948733 923 130 20 0.153846153846154 0.0216684723726977
GO:BP GO:0050854 regulation of antigen receptor-mediated signaling pathway 0.000154871508948733 68 130 6 0.0461538461538462 0.0882352941176471
GO:BP GO:0002285 lymphocyte activation involved in immune response 0.000156509837682369 190 130 9 0.0692307692307692 0.0473684210526316
GO:BP GO:0042102 positive regulation of T cell proliferation 0.000163562267860332 104 130 7 0.0538461538461538 0.0673076923076923
GO:BP GO:0110053 regulation of actin filament organization 0.000163562267860332 284 136 11 0.0808823529411765 0.0387323943661972
GO:BP GO:0051239 regulation of multicellular organismal process 0.000163562267860332 2861 111 36 0.324324324324324 0.0125830129325411
GO:BP GO:0002495 antigen processing and presentation of peptide antigen via MHC class II 0.000168363306716516 100 136 7 0.0514705882352941 0.07
GO:BP GO:0032970 regulation of actin filament-based process 0.000168885746140849 406 79 10 0.126582278481013 0.0246305418719212
GO:BP GO:1903706 regulation of hemopoiesis 0.000182351870580541 424 111 12 0.108108108108108 0.0283018867924528
GO:BP GO:0097190 apoptotic signaling pathway 0.000193564480577268 600 80 12 0.15 0.02
GO:BP GO:0050856 regulation of T cell receptor signaling pathway 0.000193991583071866 42 130 5 0.0384615384615385 0.119047619047619
GO:BP GO:0002695 negative regulation of leukocyte activation 0.000203449171485616 188 104 8 0.0769230769230769 0.0425531914893617
GO:BP GO:0002832 negative regulation of response to biotic stimulus 0.000212351479843539 100 9 3 0.333333333333333 0.03
GO:BP GO:0046641 positive regulation of alpha-beta T cell proliferation 0.000217655491557388 21 130 4 0.0307692307692308 0.19047619047619
GO:BP GO:0051246 regulation of protein metabolic process 0.000218495790388733 2704 137 40 0.291970802919708 0.014792899408284
GO:BP GO:0030097 hemopoiesis 0.000247790246309305 928 134 20 0.149253731343284 0.021551724137931
GO:BP GO:0002718 regulation of cytokine production involved in immune response 0.000249215183439019 85 11 3 0.272727272727273 0.0352941176470588
GO:BP GO:0030168 platelet activation 0.000252283933025087 160 18 4 0.222222222222222 0.025
GO:BP GO:0051716 cellular response to stimulus 0.000259468589124729 7781 13 13 1 0.0016707364092019
GO:BP GO:0032268 regulation of cellular protein metabolic process 0.000266956811732599 2541 112 33 0.294642857142857 0.012987012987013
GO:BP GO:0042592 homeostatic process 0.00027355711219028 1981 94 25 0.265957446808511 0.0126198889449773
GO:BP GO:0002520 immune system development 0.000286482456300275 1020 134 21 0.156716417910448 0.0205882352941176
GO:BP GO:0051250 negative regulation of lymphocyte activation 0.000291424879580573 156 96 7 0.0729166666666667 0.0448717948717949
GO:BP GO:0060627 regulation of vesicle-mediated transport 0.000302393094465385 536 125 14 0.112 0.0261194029850746
GO:BP GO:0050858 negative regulation of antigen receptor-mediated signaling pathway 0.000313176353747117 31 96 4 0.0416666666666667 0.129032258064516
GO:BP GO:0030029 actin filament-based process 0.000315326378769606 808 36 9 0.25 0.0111386138613861
GO:BP GO:0002367 cytokine production involved in immune response 0.000320575609350923 94 11 3 0.272727272727273 0.0319148936170213
GO:BP GO:1902165 regulation of intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator 0.0003348073853393 17 60 3 0.05 0.176470588235294
GO:BP GO:0007015 actin filament organization 0.000335985858027172 445 79 10 0.126582278481013 0.0224719101123595
GO:BP GO:0048522 positive regulation of cellular process 0.000341557794670776 5757 115 58 0.504347826086956 0.0100746916796943
GO:BP GO:0048534 hematopoietic or lymphoid organ development 0.000409214471220181 966 134 20 0.149253731343284 0.020703933747412
GO:BP GO:0050866 negative regulation of cell activation 0.000424305132215127 211 104 8 0.0769230769230769 0.037914691943128
GO:BP GO:0050896 response to stimulus 0.00049872156770233 9407 41 34 0.829268292682927 0.00361432975443818
GO:BP GO:0065007 biological regulation 0.000600939491061548 12809 29 29 1 0.00226403310172535
GO:BP GO:0045621 positive regulation of lymphocyte differentiation 0.000604446212632518 104 111 6 0.0540540540540541 0.0576923076923077
GO:BP GO:0009605 response to external stimulus 0.00066877407158588 2944 111 35 0.315315315315315 0.0118885869565217
GO:BP GO:0051651 maintenance of location in cell 0.000704692840520878 223 137 9 0.0656934306569343 0.0403587443946188
GO:BP GO:0045639 positive regulation of myeloid cell differentiation 0.000722276382980672 103 71 5 0.0704225352112676 0.0485436893203883
GO:BP GO:0030036 actin cytoskeleton organization 0.000747177414105738 709 79 12 0.151898734177215 0.0169252468265162
GO:BP GO:0001819 positive regulation of cytokine production 0.000780201143006067 452 104 11 0.105769230769231 0.0243362831858407
GO:BP GO:0030833 regulation of actin filament polymerization 0.000782653573927057 177 136 8 0.0588235294117647 0.0451977401129944
GO:BP GO:0006518 peptide metabolic process 0.000942655139199012 955 133 19 0.142857142857143 0.0198952879581152
GO:BP GO:0051493 regulation of cytoskeleton organization 0.000955805767368206 531 36 7 0.194444444444444 0.0131826741996234
GO:BP GO:0043408 regulation of MAPK cascade 0.000970283012293762 730 104 14 0.134615384615385 0.0191780821917808
GO:BP GO:0002468 dendritic cell antigen processing and presentation 0.00102830065613729 14 111 3 0.027027027027027 0.214285714285714
GO:BP GO:0050864 regulation of B cell activation 0.00105304818137122 194 130 8 0.0615384615384615 0.0412371134020619
GO:BP GO:1902533 positive regulation of intracellular signal transduction 0.00107465199839507 1037 104 17 0.163461538461538 0.0163934426229508
GO:BP GO:0008104 protein localization 0.00108955249641739 2770 71 24 0.338028169014085 0.00866425992779783
GO:BP GO:0038093 Fc receptor signaling pathway 0.00108955249641739 238 137 9 0.0656934306569343 0.0378151260504202
GO:BP GO:0045454 cell redox homeostasis 0.00109915618882124 58 140 5 0.0357142857142857 0.0862068965517241
GO:BP GO:0046634 regulation of alpha-beta T cell activation 0.00120181147248238 102 130 6 0.0461538461538462 0.0588235294117647
GO:BP GO:2001242 regulation of intrinsic apoptotic signaling pathway 0.00123169011227965 167 80 6 0.075 0.0359281437125748
GO:BP GO:0052548 regulation of endopeptidase activity 0.0012648898383623 437 134 12 0.0895522388059701 0.0274599542334096
GO:BP GO:0044070 regulation of anion transport 0.0012927412492099 896 99 15 0.151515151515152 0.0167410714285714
GO:BP GO:0008064 regulation of actin polymerization or depolymerization 0.00134039252405079 193 136 8 0.0588235294117647 0.0414507772020725
GO:BP GO:0065009 regulation of molecular function 0.00135375643158985 3221 139 43 0.309352517985612 0.0133498913380938
GO:BP GO:0030832 regulation of actin filament length 0.00137871782859013 194 136 8 0.0588235294117647 0.0412371134020619
GO:BP GO:0045010 actin nucleation 0.00138244391877954 57 79 4 0.0506329113924051 0.0701754385964912
GO:BP GO:0046640 regulation of alpha-beta T cell proliferation 0.00138417748257454 35 130 4 0.0307692307692308 0.114285714285714
GO:BP GO:0032649 regulation of interferon-gamma production 0.00141000912794913 110 125 6 0.048 0.0545454545454545
GO:BP GO:0030041 actin filament polymerization 0.00144710028526567 196 136 8 0.0588235294117647 0.0408163265306122
GO:BP GO:1902253 regulation of intrinsic apoptotic signaling pathway by p53 class mediator 0.00145382051987614 29 60 3 0.05 0.103448275862069
GO:BP GO:0048013 ephrin receptor signaling pathway 0.00145382051987614 88 20 3 0.15 0.0340909090909091
GO:BP GO:0002761 regulation of myeloid leukocyte differentiation 0.00146997151244 123 71 5 0.0704225352112676 0.040650406504065
GO:BP GO:0045619 regulation of lymphocyte differentiation 0.00146997151244 180 111 7 0.0630630630630631 0.0388888888888889
GO:BP GO:0030101 natural killer cell activation 0.00147416972204579 84 104 5 0.0480769230769231 0.0595238095238095
GO:BP GO:0045088 regulation of innate immune response 0.00147460228684704 309 137 10 0.072992700729927 0.0323624595469256
GO:BP GO:0060341 regulation of cellular localization 0.0015005136233068 851 130 17 0.130769230769231 0.0199764982373678
GO:BP GO:0046631 alpha-beta T cell activation 0.00153617702734183 155 130 7 0.0538461538461538 0.0451612903225806
GO:BP GO:0034622 cellular protein-containing complex assembly 0.00155457750049624 1107 111 18 0.162162162162162 0.016260162601626
GO:BP GO:0045730 respiratory burst 0.0016243641533749 35 52 3 0.0576923076923077 0.0857142857142857
GO:BP GO:0006811 ion transport 0.00163805654117527 3661 99 36 0.363636363636364 0.00983337885823546
GO:BP GO:0032609 interferon-gamma production 0.0017175346894 115 125 6 0.048 0.0521739130434783
GO:BP GO:0051051 negative regulation of transport 0.00172073760499282 474 129 12 0.0930232558139535 0.0253164556962025
GO:BP GO:0001894 tissue homeostasis 0.00172073760499282 270 54 6 0.111111111111111 0.0222222222222222
GO:BP GO:0071705 nitrogen compound transport 0.00176157166407942 2322 71 21 0.295774647887324 0.00904392764857881
GO:BP GO:0002573 myeloid leukocyte differentiation 0.00176974642408669 213 130 8 0.0615384615384615 0.0375586854460094
GO:BP GO:0002286 T cell activation involved in immune response 0.00180291641013783 112 130 6 0.0461538461538462 0.0535714285714286
GO:BP GO:1902903 regulation of supramolecular fiber organization 0.0018896752764167 387 136 11 0.0808823529411765 0.0284237726098191
GO:BP GO:0048519 negative regulation of biological process 0.0020008985088655 5757 137 64 0.467153284671533 0.0111169011638006
GO:BP GO:0022618 ribonucleoprotein complex assembly 0.00201653859516773 197 108 7 0.0648148148148148 0.0355329949238579
GO:BP GO:0050789 regulation of biological process 0.00204346770395989 12091 49 44 0.897959183673469 0.00363907038292945
GO:BP GO:0052547 regulation of peptidase activity 0.00205483097369174 467 134 12 0.0895522388059701 0.0256959314775161
GO:BP GO:2001233 regulation of apoptotic signaling pathway 0.00211519443656242 363 60 7 0.116666666666667 0.0192837465564738
GO:BP GO:0042886 amide transport 0.00212187216387208 2007 71 19 0.267605633802817 0.00946686596910812
GO:BP GO:0045185 maintenance of protein location 0.0021308344771208 98 53 4 0.0754716981132075 0.0408163265306122
GO:BP GO:0001895 retina homeostasis 0.0021308344771208 79 26 3 0.115384615384615 0.0379746835443038
GO:BP GO:0072657 protein localization to membrane 0.00218937236142344 665 69 10 0.144927536231884 0.0150375939849624
GO:BP GO:0006413 translational initiation 0.00220595002516675 201 108 7 0.0648148148148148 0.0348258706467662
GO:BP GO:0016064 immunoglobulin mediated immune response 0.0022709623483833 223 130 8 0.0615384615384615 0.0358744394618834
GO:BP GO:0008219 cell death 0.00233839033981071 2292 133 32 0.240601503759398 0.0139616055846422
GO:BP GO:0071826 ribonucleoprotein complex subunit organization 0.00236545613461245 204 108 7 0.0648148148148148 0.0343137254901961
GO:BP GO:0019724 B cell mediated immunity 0.00242268284436874 226 130 8 0.0615384615384615 0.0353982300884956
GO:BP GO:0090713 immunological memory process 0.00242268284436874 17 130 3 0.0230769230769231 0.176470588235294
GO:BP GO:0045582 positive regulation of T cell differentiation 0.00255212379956537 91 111 5 0.045045045045045 0.0549450549450549
GO:BP GO:0051235 maintenance of location 0.00260311697695604 337 137 10 0.072992700729927 0.029673590504451
GO:BP GO:1902229 regulation of intrinsic apoptotic signaling pathway in response to DNA damage 0.00260350021872642 37 60 3 0.05 0.0810810810810811
GO:BP GO:1902531 regulation of intracellular signal transduction 0.00269300706139703 1842 104 23 0.221153846153846 0.0124864277958741
GO:BP GO:0008154 actin polymerization or depolymerization 0.00294430343532569 223 136 8 0.0588235294117647 0.0358744394618834
GO:BP GO:0031347 regulation of defense response 0.00296946443331756 704 137 15 0.109489051094891 0.0213068181818182
GO:BP GO:0009617 response to bacterium 0.00308244173000354 743 9 4 0.444444444444444 0.0053835800807537
GO:BP GO:2000106 regulation of leukocyte apoptotic process 0.00308337971363649 82 71 4 0.0563380281690141 0.0487804878048781
GO:BP GO:0097066 response to thyroid hormone 0.00309390929520571 26 92 3 0.0326086956521739 0.115384615384615
GO:BP GO:0051130 positive regulation of cellular component organization 0.00309555536785766 1153 114 18 0.157894736842105 0.01561144839549
GO:BP GO:0048523 negative regulation of cellular process 0.00310130612995255 5139 137 58 0.423357664233577 0.0112862424596225
GO:BP GO:0010468 regulation of gene expression 0.00310130612995255 5196 9 8 0.888888888888889 0.00153964588144727
GO:BP GO:1903131 mononuclear cell differentiation 0.00314495464807497 430 111 10 0.0900900900900901 0.0232558139534884
GO:BP GO:0050900 leukocyte migration 0.00316864255507802 511 130 12 0.0923076923076923 0.0234833659491194
GO:BP GO:0097193 intrinsic apoptotic signaling pathway 0.00319254879417855 294 80 7 0.0875 0.0238095238095238
GO:BP GO:0002831 regulation of response to biotic stimulus 0.00319254879417855 415 137 11 0.0802919708029197 0.0265060240963855
GO:BP GO:0097435 supramolecular fiber organization 0.00324172964921823 734 79 11 0.139240506329114 0.0149863760217984
GO:BP GO:0033036 macromolecule localization 0.00324172964921823 3218 71 25 0.352112676056338 0.00776880049720323
GO:BP GO:0007596 blood coagulation 0.00324172964921823 347 18 4 0.222222222222222 0.0115273775216138
GO:BP GO:0080135 regulation of cellular response to stress 0.00324172964921823 725 80 11 0.1375 0.0151724137931034
GO:BP GO:0050790 regulation of catalytic activity 0.00328154368908626 2545 139 35 0.251798561151079 0.0137524557956778
GO:BP GO:0012501 programmed cell death 0.00330873547754233 2143 133 30 0.225563909774436 0.0139990667288847
GO:BP GO:0007599 hemostasis 0.00330873547754233 351 18 4 0.222222222222222 0.0113960113960114
GO:BP GO:0002347 response to tumor cell 0.00331194346710617 26 96 3 0.03125 0.115384615384615
GO:BP GO:0002433 immune response-regulating cell surface receptor signaling pathway involved in phagocytosis 0.00331783756092968 135 125 6 0.048 0.0444444444444444
GO:BP GO:0038096 Fc-gamma receptor signaling pathway involved in phagocytosis 0.00331783756092968 135 125 6 0.048 0.0444444444444444
GO:BP GO:0044093 positive regulation of molecular function 0.00331783756092968 1771 110 23 0.209090909090909 0.012987012987013
GO:BP GO:0050817 coagulation 0.00335833167779188 354 18 4 0.222222222222222 0.0112994350282486
GO:BP GO:0032101 regulation of response to external stimulus 0.00337935195562856 1051 137 19 0.138686131386861 0.0180780209324453
GO:BP GO:0051128 regulation of cellular component organization 0.00340943975608686 2412 114 29 0.254385964912281 0.0120232172470978
GO:BP GO:0007162 negative regulation of cell adhesion 0.00343718892530647 304 104 8 0.0769230769230769 0.0263157894736842
GO:BP GO:0038094 Fc-gamma receptor signaling pathway 0.00350847181163641 137 125 6 0.048 0.0437956204379562
GO:BP GO:0043270 positive regulation of ion transport 0.00369694193714057 694 99 12 0.121212121212121 0.0172910662824208
GO:BP GO:0051881 regulation of mitochondrial membrane potential 0.00374944486376824 74 85 4 0.0470588235294118 0.0540540540540541
GO:BP GO:0071349 cellular response to interleukin-12 0.00375050883740715 49 129 4 0.0310077519379845 0.0816326530612245
GO:BP GO:0032271 regulation of protein polymerization 0.00381050914110418 236 136 8 0.0588235294117647 0.0338983050847458
GO:BP GO:0050793 regulation of developmental process 0.00383851355922826 2605 112 30 0.267857142857143 0.0115163147792706
GO:BP GO:0048585 negative regulation of response to stimulus 0.00383851355922826 1733 12 6 0.5 0.00346220427005193
GO:BP GO:0031349 positive regulation of defense response 0.00392020456604468 362 137 10 0.072992700729927 0.0276243093922652
GO:BP GO:0031579 membrane raft organization 0.00392020456604468 26 104 3 0.0288461538461538 0.115384615384615
GO:BP GO:0033043 regulation of organelle organization 0.00392020456604468 1203 94 16 0.170212765957447 0.0133000831255195
GO:BP GO:0070671 response to interleukin-12 0.00393424796200474 50 129 4 0.0310077519379845 0.08
GO:BP GO:0034613 cellular protein localization 0.00393424796200474 2014 99 23 0.232323232323232 0.0114200595829196
GO:BP GO:0002431 Fc receptor mediated stimulatory signaling pathway 0.00393424796200474 141 125 6 0.048 0.0425531914893617
GO:BP GO:0042771 intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator 0.003959799661158 45 60 3 0.05 0.0666666666666667
GO:BP GO:0006915 apoptotic process 0.00405990035683599 1990 132 28 0.212121212121212 0.014070351758794
GO:BP GO:0019725 cellular homeostasis 0.00414584656922045 981 104 15 0.144230769230769 0.0152905198776758
GO:BP GO:0070727 cellular macromolecule localization 0.00415432511480048 2024 99 23 0.232323232323232 0.0113636363636364
GO:BP GO:0008284 positive regulation of cell population proliferation 0.00416794828461893 982 104 15 0.144230769230769 0.0152749490835031
GO:BP GO:0050794 regulation of cellular process 0.00417236012293125 11473 49 42 0.857142857142857 0.0036607687614399
GO:BP GO:0008283 cell population proliferation 0.0042927775740409 2054 104 24 0.230769230769231 0.0116845180136319
GO:BP GO:0050868 negative regulation of T cell activation 0.0042927775740409 123 96 5 0.0520833333333333 0.040650406504065
GO:BP GO:0030098 lymphocyte differentiation 0.00437221631513097 376 111 9 0.0810810810810811 0.023936170212766
GO:BP GO:2000249 regulation of actin cytoskeleton reorganization 0.00439184559618312 40 71 3 0.0422535211267606 0.075
GO:BP GO:0051495 positive regulation of cytoskeleton organization 0.00439451880520009 231 79 6 0.0759493670886076 0.025974025974026
GO:BP GO:0032103 positive regulation of response to external stimulus 0.00447965251450008 513 137 12 0.0875912408759124 0.0233918128654971
GO:BP GO:0061024 membrane organization 0.00449960738919004 973 106 15 0.141509433962264 0.0154162384378212
GO:BP GO:0032703 negative regulation of interleukin-2 production 0.00458640538943384 28 104 3 0.0288461538461538 0.107142857142857
GO:BP GO:0090087 regulation of peptide transport 0.00460904923223329 618 99 11 0.111111111111111 0.0177993527508091
GO:BP GO:0006605 protein targeting 0.00460904923223329 441 96 9 0.09375 0.0204081632653061
GO:BP GO:0045637 regulation of myeloid cell differentiation 0.00475685510399059 263 71 6 0.0845070422535211 0.0228136882129278
GO:BP GO:0022408 negative regulation of cell-cell adhesion 0.00480225909207898 194 96 6 0.0625 0.0309278350515464
GO:BP GO:0034314 Arp2/3 complex-mediated actin nucleation 0.00493422407209791 41 73 3 0.0410958904109589 0.0731707317073171
GO:BP GO:0070371 ERK1 and ERK2 cascade 0.00506806103521113 329 104 8 0.0769230769230769 0.0243161094224924
GO:BP GO:0042113 B cell activation 0.0051568263835511 330 104 8 0.0769230769230769 0.0242424242424242
GO:BP GO:0002833 positive regulation of response to biotic stimulus 0.00519931206805134 250 137 8 0.0583941605839416 0.032
GO:BP GO:0031329 regulation of cellular catabolic process 0.0054341228911521 866 134 16 0.119402985074627 0.0184757505773672
GO:BP GO:0072594 establishment of protein localization to organelle 0.00543859689485011 584 124 12 0.0967741935483871 0.0205479452054795
GO:BP GO:1902624 positive regulation of neutrophil migration 0.00551810730736355 30 105 3 0.0285714285714286 0.1
GO:BP GO:0070228 regulation of lymphocyte apoptotic process 0.00553126206904974 55 57 3 0.0526315789473684 0.0545454545454545
GO:BP GO:0038061 NIK/NF-kappaB signaling 0.00553126206904974 194 137 7 0.0510948905109489 0.0360824742268041
GO:BP GO:0032535 regulation of cellular component size 0.00557228992959947 388 136 10 0.0735294117647059 0.0257731958762887
GO:BP GO:0042100 B cell proliferation 0.00557228992959947 98 130 5 0.0384615384615385 0.0510204081632653
GO:BP GO:0043603 cellular amide metabolic process 0.00570264398651289 1241 133 20 0.150375939849624 0.016116035455278
GO:BP GO:2000107 negative regulation of leukocyte apoptotic process 0.00574376015715768 45 71 3 0.0422535211267606 0.0666666666666667
GO:BP GO:1902743 regulation of lamellipodium organization 0.00601519199965287 55 136 4 0.0294117647058824 0.0727272727272727
GO:BP GO:0032615 interleukin-12 production 0.00605428338095716 60 125 4 0.032 0.0666666666666667
GO:BP GO:0032655 regulation of interleukin-12 production 0.00605428338095716 60 125 4 0.032 0.0666666666666667
GO:BP GO:0032872 regulation of stress-activated MAPK cascade 0.00607335683575539 190 69 5 0.072463768115942 0.0263157894736842
GO:BP GO:0031532 actin cytoskeleton reorganization 0.00613941972920052 106 71 4 0.0563380281690141 0.0377358490566038
GO:BP GO:0010984 regulation of lipoprotein particle clearance 0.00616645143170702 36 92 3 0.0326086956521739 0.0833333333333333
GO:BP GO:0043281 regulation of cysteine-type endopeptidase activity involved in apoptotic process 0.0062411562547939 217 126 7 0.0555555555555556 0.032258064516129
GO:BP GO:0048871 multicellular organismal homeostasis 0.00641094081591276 530 85 9 0.105882352941176 0.0169811320754717
GO:BP GO:0070302 regulation of stress-activated protein kinase signaling cascade 0.00642594838183063 193 69 5 0.072463768115942 0.0259067357512953
GO:BP GO:0071887 leukocyte apoptotic process 0.00647838292275543 108 71 4 0.0563380281690141 0.037037037037037
GO:BP GO:0060548 negative regulation of cell death 0.00647838292275543 1038 126 17 0.134920634920635 0.0163776493256262
GO:BP GO:1904951 positive regulation of establishment of protein localization 0.00655690064572201 345 130 9 0.0692307692307692 0.0260869565217391
GO:BP GO:0034113 heterotypic cell-cell adhesion 0.006649994790334 62 125 4 0.032 0.0645161290322581
GO:BP GO:0006816 calcium ion transport 0.00683364608884761 436 104 9 0.0865384615384615 0.0206422018348624
GO:BP GO:0099173 postsynapse organization 0.00701557233860825 169 21 3 0.142857142857143 0.0177514792899408
GO:BP GO:0010638 positive regulation of organelle organization 0.00710126805610764 603 125 12 0.096 0.0199004975124378
GO:BP GO:1903038 negative regulation of leukocyte cell-cell adhesion 0.00710126805610764 142 96 5 0.0520833333333333 0.0352112676056338
GO:BP GO:0032507 maintenance of protein location in cell 0.00720650091227287 67 53 3 0.0566037735849057 0.0447761194029851
GO:BP GO:0042127 regulation of cell population proliferation 0.00731301160991596 1774 104 21 0.201923076923077 0.0118376550169109
GO:BP GO:0030099 myeloid cell differentiation 0.00746511110501389 428 130 10 0.0769230769230769 0.0233644859813084
GO:BP GO:0006749 glutathione metabolic process 0.00752963319127006 63 129 4 0.0310077519379845 0.0634920634920635
GO:BP GO:0043410 positive regulation of MAPK cascade 0.00759087156537337 539 104 10 0.0961538461538462 0.0185528756957328
GO:BP GO:0051247 positive regulation of protein metabolic process 0.00767214644938626 1564 110 20 0.181818181818182 0.0127877237851662
GO:BP GO:0030888 regulation of B cell proliferation 0.00767214644938626 63 130 4 0.0307692307692308 0.0634920634920635
GO:BP GO:0031589 cell-substrate adhesion 0.00767214644938626 367 39 5 0.128205128205128 0.0136239782016349
GO:BP GO:0032388 positive regulation of intracellular transport 0.00770420969360217 229 92 6 0.0652173913043478 0.0262008733624454
GO:BP GO:0030838 positive regulation of actin filament polymerization 0.00770660966252031 104 79 4 0.0506329113924051 0.0384615384615385
GO:BP GO:0010467 gene expression 0.00784076996788268 6179 9 8 0.888888888888889 0.00129470788153423
GO:BP GO:0006820 anion transport 0.00784076996788268 2889 71 22 0.309859154929577 0.00761509172724126
GO:BP GO:0050766 positive regulation of phagocytosis 0.00795585097976878 67 125 4 0.032 0.0597014925373134
GO:BP GO:0044087 regulation of cellular component biogenesis 0.00807136278391397 990 136 17 0.125 0.0171717171717172
GO:BP GO:2000026 regulation of multicellular organismal development 0.00807602423363686 1447 111 19 0.171171171171171 0.0131306150656531
GO:BP GO:0065003 protein-containing complex assembly 0.00808630787921874 1680 111 21 0.189189189189189 0.0125
GO:BP GO:0060255 regulation of macromolecule metabolic process 0.0081112348817255 6603 12 10 0.833333333333333 0.00151446312282296
GO:BP GO:0014068 positive regulation of phosphatidylinositol 3-kinase signaling 0.00819768086594704 93 91 4 0.043956043956044 0.043010752688172
GO:BP GO:2001243 negative regulation of intrinsic apoptotic signaling pathway 0.00848614569641824 100 39 3 0.0769230769230769 0.03
GO:BP GO:0044089 positive regulation of cellular component biogenesis 0.00848614569641824 540 125 11 0.088 0.0203703703703704
GO:BP GO:0045089 positive regulation of innate immune response 0.00848614569641824 216 137 7 0.0510948905109489 0.0324074074074074
GO:BP GO:0048870 cell motility 0.00848614569641824 1828 23 8 0.347826086956522 0.00437636761487965
GO:BP GO:0051674 localization of cell 0.00848614569641824 1828 23 8 0.347826086956522 0.00437636761487965
GO:BP GO:0015833 peptide transport 0.00851141134946488 1971 71 17 0.23943661971831 0.00862506341958397
GO:BP GO:0046718 viral entry into host cell 0.00851141134946488 141 61 4 0.0655737704918033 0.0283687943262411
GO:BP GO:0006928 movement of cell or subcellular component 0.00866845808545745 2311 23 9 0.391304347826087 0.00389441800086543
GO:BP GO:0051223 regulation of protein transport 0.00884736497717866 586 99 10 0.101010101010101 0.0170648464163823
GO:BP GO:0032270 positive regulation of cellular protein metabolic process 0.00886208945786686 1477 110 19 0.172727272727273 0.012863913337847
GO:BP GO:0010941 regulation of cell death 0.00896514301281708 1720 132 24 0.181818181818182 0.013953488372093
GO:BP GO:0009967 positive regulation of signal transduction 0.00904163640050544 1598 110 20 0.181818181818182 0.0125156445556946
GO:BP GO:0050878 regulation of body fluid levels 0.00911538226464468 514 18 4 0.222222222222222 0.00778210116731518
GO:BP GO:2000116 regulation of cysteine-type endopeptidase activity 0.00925158663914375 240 126 7 0.0555555555555556 0.0291666666666667
GO:BP GO:0007010 cytoskeleton organization 0.00932290545327909 1423 36 9 0.25 0.00632466619817287
GO:BP GO:0009057 macromolecule catabolic process 0.00932544046163355 1468 137 22 0.160583941605839 0.0149863760217984
GO:BP GO:0070201 regulation of establishment of protein localization 0.00932723341193549 611 130 12 0.0923076923076923 0.0196399345335516
GO:BP GO:0010604 positive regulation of macromolecule metabolic process 0.00951709887379561 3483 11 7 0.636363636363636 0.00200976169968418
GO:BP GO:1903829 positive regulation of cellular protein localization 0.00962163486874876 303 130 8 0.0615384615384615 0.0264026402640264
GO:BP GO:0001818 negative regulation of cytokine production 0.00976686296992191 381 104 8 0.0769230769230769 0.020997375328084
GO:BP GO:0007160 cell-matrix adhesion 0.00978285757451802 235 39 4 0.102564102564103 0.0170212765957447
GO:BP GO:0048878 chemical homeostasis 0.00978285757451802 1229 94 15 0.159574468085106 0.0122050447518308
GO:BP GO:0035556 intracellular signal transduction 0.00985722451348483 2772 139 35 0.251798561151079 0.0126262626262626
GO:BP GO:0009894 regulation of catabolic process 0.00985722451348483 1033 134 17 0.126865671641791 0.0164569215876089
GO:BP GO:0071702 organic substance transport 0.00985722451348483 2766 71 21 0.295774647887324 0.00759219088937093
GO:BP GO:0010605 negative regulation of macromolecule metabolic process 0.00985992059774179 3241 120 35 0.291666666666667 0.0107991360691145
GO:BP GO:0070227 lymphocyte apoptotic process 0.00991430588753491 74 57 3 0.0526315789473684 0.0405405405405405
GO:BP GO:0002724 regulation of T cell cytokine production 0.0101743032888241 33 130 3 0.0230769230769231 0.0909090909090909
GO:BP GO:0002861 regulation of inflammatory response to antigenic stimulus 0.0101743032888241 33 130 3 0.0230769230769231 0.0909090909090909
GO:BP GO:1903793 positive regulation of anion transport 0.0105063489903838 504 99 9 0.0909090909090909 0.0178571428571429
GO:BP GO:0044248 cellular catabolic process 0.0105314724945472 2347 140 31 0.221428571428571 0.0132083510864934
GO:BP GO:0016043 cellular component organization 0.0105314724945472 6566 114 57 0.5 0.00868108437404813
GO:BP GO:0044409 entry into host 0.010697871095262 154 61 4 0.0655737704918033 0.025974025974026
GO:BP GO:0042060 wound healing 0.0107119999597202 549 18 4 0.222222222222222 0.00728597449908925
GO:BP GO:0022607 cellular component assembly 0.0109037682966335 3010 111 31 0.279279279279279 0.0102990033222591
GO:BP GO:0051283 negative regulation of sequestering of calcium ion 0.011251228193801 124 129 5 0.0387596899224806 0.0403225806451613
GO:BP GO:0051924 regulation of calcium ion transport 0.01126312110198 259 91 6 0.0659340659340659 0.0231660231660232
GO:BP GO:1902622 regulation of neutrophil migration 0.0113841543235271 43 105 3 0.0285714285714286 0.0697674418604651
GO:BP GO:0044267 cellular protein metabolic process 0.0115192865780446 5229 112 47 0.419642857142857 0.00898833428953911
GO:BP GO:0070372 regulation of ERK1 and ERK2 cascade 0.0116304519446971 309 104 7 0.0673076923076923 0.0226537216828479
GO:BP GO:0051282 regulation of sequestering of calcium ion 0.0118387600278606 126 129 5 0.0387596899224806 0.0396825396825397
GO:BP GO:0072332 intrinsic apoptotic signaling pathway by p53 class mediator 0.0120383631063374 77 60 3 0.05 0.038961038961039
GO:BP GO:0051258 protein polymerization 0.0121617935180135 305 79 6 0.0759493670886076 0.019672131147541
GO:BP GO:0051222 positive regulation of protein transport 0.0123211088776166 329 99 7 0.0707070707070707 0.0212765957446809
GO:BP GO:0009611 response to wounding 0.0123850081049844 674 92 10 0.108695652173913 0.0148367952522255
GO:BP GO:0008360 regulation of cell shape 0.0123920021920799 154 107 5 0.0467289719626168 0.0324675324675325
GO:BP GO:0023056 positive regulation of signaling 0.012515936835035 1782 110 21 0.190909090909091 0.0117845117845118
GO:BP GO:0010959 regulation of metal ion transport 0.0128553638151946 268 91 6 0.0659340659340659 0.0223880597014925
GO:BP GO:0043069 negative regulation of programmed cell death 0.0128553638151946 943 126 15 0.119047619047619 0.0159066808059385
GO:BP GO:0044265 cellular macromolecule catabolic process 0.0128553638151946 1231 137 19 0.138686131386861 0.0154346060113729
GO:BP GO:0002823 negative regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains 0.0129149312560391 46 104 3 0.0288461538461538 0.0652173913043478
GO:BP GO:0022604 regulation of cell morphogenesis 0.012917666317788 309 136 8 0.0588235294117647 0.0258899676375405
GO:BP GO:0051248 negative regulation of protein metabolic process 0.012917666317788 1151 104 15 0.144230769230769 0.0130321459600348
GO:BP GO:0043067 regulation of programmed cell death 0.0129855676162118 1582 132 22 0.166666666666667 0.0139064475347661
GO:BP GO:0051208 sequestering of calcium ion 0.0130789093845332 130 129 5 0.0387596899224806 0.0384615384615385
GO:BP GO:0002260 lymphocyte homeostasis 0.0131078702026638 61 79 3 0.0379746835443038 0.0491803278688525
GO:BP GO:0042176 regulation of protein catabolic process 0.0132264397489899 401 130 9 0.0692307692307692 0.0224438902743142
GO:BP GO:1902905 positive regulation of supramolecular fiber organization 0.0132264397489899 214 79 5 0.0632911392405063 0.0233644859813084
GO:BP GO:0045580 regulation of T cell differentiation 0.0132264397489899 152 111 5 0.045045045045045 0.0328947368421053
GO:BP GO:0009893 positive regulation of metabolic process 0.0132801101303753 3783 110 36 0.327272727272727 0.00951625693893735
GO:BP GO:0019222 regulation of metabolic process 0.0133419649012911 7148 12 10 0.833333333333333 0.00139899272523783
GO:BP GO:0043254 regulation of protein-containing complex assembly 0.0133633387755727 460 136 10 0.0735294117647059 0.0217391304347826
GO:BP GO:0051336 regulation of hydrolase activity 0.0133954046694002 1321 110 17 0.154545454545455 0.0128690386071158
GO:BP GO:2000516 positive regulation of CD4-positive, alpha-beta T cell activation 0.0135187457801054 38 130 3 0.0230769230769231 0.0789473684210526
GO:BP GO:0040011 locomotion 0.0135187457801054 2028 23 8 0.347826086956522 0.00394477317554241
GO:BP GO:1903362 regulation of cellular protein catabolic process 0.013649309990008 257 130 7 0.0538461538461538 0.0272373540856031
GO:BP GO:0010629 negative regulation of gene expression 0.0146241050320512 1460 118 19 0.161016949152542 0.013013698630137
GO:BP GO:0043549 regulation of kinase activity 0.0146241050320512 921 59 9 0.152542372881356 0.00977198697068404
GO:BP GO:0015031 protein transport 0.0146343857842581 1929 71 16 0.225352112676056 0.00829445308449974
GO:BP GO:0045597 positive regulation of cell differentiation 0.0146744548395276 879 111 13 0.117117117117117 0.0147895335608646
GO:BP GO:0030001 metal ion transport 0.0147211496238763 514 104 9 0.0865384615384615 0.0175097276264591
GO:BP GO:0031399 regulation of protein modification process 0.0150482084320096 1671 104 19 0.182692307692308 0.0113704368641532
GO:BP GO:0050853 B cell receptor signaling pathway 0.0151347935383249 135 130 5 0.0384615384615385 0.037037037037037
GO:BP GO:0052126 movement in host environment 0.0155106172086553 177 61 4 0.0655737704918033 0.0225988700564972
GO:BP GO:0060249 anatomical structure homeostasis 0.0156598483266048 482 54 6 0.111111111111111 0.012448132780083
GO:BP GO:1901700 response to oxygen-containing compound 0.0158516630892683 1739 72 15 0.208333333333333 0.00862564692351926
GO:BP GO:0050731 positive regulation of peptidyl-tyrosine phosphorylation 0.0158670380232155 198 130 6 0.0461538461538462 0.0303030303030303
GO:BP GO:1901222 regulation of NIK/NF-kappaB signaling 0.0158670380232155 113 96 4 0.0416666666666667 0.0353982300884956
GO:BP GO:0040017 positive regulation of locomotion 0.0160858777824528 606 107 10 0.0934579439252336 0.0165016501650165
GO:BP GO:0002820 negative regulation of adaptive immune response 0.0161359089314522 51 104 3 0.0288461538461538 0.0588235294117647
GO:BP GO:0030890 positive regulation of B cell proliferation 0.0161964741104351 41 130 3 0.0230769230769231 0.0731707317073171
GO:BP GO:0045595 regulation of cell differentiation 0.0161964741104351 1679 112 20 0.178571428571429 0.0119118522930316
GO:BP GO:0048015 phosphatidylinositol-mediated signaling 0.0161964741104351 197 91 5 0.0549450549450549 0.0253807106598985
GO:BP GO:0072659 protein localization to plasma membrane 0.016308432772711 283 92 6 0.0652173913043478 0.0212014134275618
GO:BP GO:0051094 positive regulation of developmental process 0.016359834367676 1341 111 17 0.153153153153153 0.0126771066368382
GO:BP GO:0050730 regulation of peptidyl-tyrosine phosphorylation 0.0167121837971782 269 130 7 0.0538461538461538 0.0260223048327138
GO:BP GO:0051241 negative regulation of multicellular organismal process 0.0167283598479757 1160 107 15 0.14018691588785 0.0129310344827586
GO:BP GO:0051048 negative regulation of secretion 0.0167283598479757 176 103 5 0.0485436893203883 0.0284090909090909
GO:BP GO:0006897 endocytosis 0.0167283598479757 696 65 8 0.123076923076923 0.0114942528735632
GO:BP GO:0032273 positive regulation of protein polymerization 0.0168262720304194 141 79 4 0.0506329113924051 0.0283687943262411
GO:BP GO:0048017 inositol lipid-mediated signaling 0.0171755681440441 201 91 5 0.0549450549450549 0.0248756218905473
GO:BP GO:0032269 negative regulation of cellular protein metabolic process 0.0174061628807105 1082 104 14 0.134615384615385 0.0129390018484288
GO:BP GO:0002889 regulation of immunoglobulin mediated immune response 0.0181872679639069 54 104 3 0.0288461538461538 0.0555555555555556
GO:BP GO:0002712 regulation of B cell mediated immunity 0.0181872679639069 54 104 3 0.0288461538461538 0.0555555555555556
GO:BP GO:0072655 establishment of protein localization to mitochondrion 0.0182333455740498 143 80 4 0.05 0.027972027972028
GO:BP GO:0071840 cellular component organization or biogenesis 0.0183827199598466 6760 114 57 0.5 0.00843195266272189
GO:BP GO:0043066 negative regulation of apoptotic process 0.0185118013934879 921 85 11 0.129411764705882 0.011943539630836
GO:BP GO:0051403 stress-activated MAPK cascade 0.0185332464445247 272 69 5 0.072463768115942 0.0183823529411765
GO:BP GO:0032880 regulation of protein localization 0.0185978026457241 922 85 11 0.129411764705882 0.0119305856832972
GO:BP GO:0030162 regulation of proteolysis 0.0186751336399896 752 134 13 0.0970149253731343 0.0172872340425532
GO:BP GO:0031334 positive regulation of protein-containing complex assembly 0.0189779639227027 263 103 6 0.058252427184466 0.0228136882129278
GO:BP GO:0042981 regulation of apoptotic process 0.0193701863216572 1549 132 21 0.159090909090909 0.013557133634603
GO:BP GO:0070585 protein localization to mitochondrion 0.0196181408118849 147 80 4 0.05 0.0272108843537415
GO:BP GO:0010591 regulation of lamellipodium assembly 0.0196740261318632 43 136 3 0.0220588235294118 0.0697674418604651
GO:BP GO:0030593 neutrophil chemotaxis 0.0200187128663177 103 57 3 0.0526315789473684 0.029126213592233
GO:BP GO:0002791 regulation of peptide secretion 0.0201386486826612 325 85 6 0.0705882352941176 0.0184615384615385
GO:BP GO:0006401 RNA catabolic process 0.0204050320606852 424 134 9 0.0671641791044776 0.0212264150943396
GO:BP GO:0033365 protein localization to organelle 0.0204050320606852 1017 137 16 0.116788321167883 0.015732546705998
GO:BP GO:0050918 positive chemotaxis 0.0208122586074133 68 88 3 0.0340909090909091 0.0441176470588235
GO:BP GO:0014066 regulation of phosphatidylinositol 3-kinase signaling 0.0212546884797163 133 91 4 0.043956043956044 0.0300751879699248
GO:BP GO:0035722 interleukin-12-mediated signaling pathway 0.0213064467205454 47 129 3 0.0232558139534884 0.0638297872340425
GO:BP GO:0006734 NADH metabolic process 0.0217109380491813 46 133 3 0.0225563909774436 0.0652173913043478
GO:BP GO:0050871 positive regulation of B cell activation 0.0217512193806115 151 130 5 0.0384615384615385 0.033112582781457
GO:BP GO:0045184 establishment of protein localization 0.0219462074171171 2035 71 16 0.225352112676056 0.00786240786240786
GO:BP GO:0050764 regulation of phagocytosis 0.0219462074171171 98 125 4 0.032 0.0408163265306122
GO:BP GO:0002218 activation of innate immune response 0.0220314692006816 144 137 5 0.0364963503649635 0.0347222222222222
GO:BP GO:0061515 myeloid cell development 0.0221030182499498 67 92 3 0.0326086956521739 0.0447761194029851
GO:BP GO:0031098 stress-activated protein kinase signaling cascade 0.0221120301109032 288 69 5 0.072463768115942 0.0173611111111111
GO:BP GO:0008630 intrinsic apoptotic signaling pathway in response to DNA damage 0.02216910505037 103 60 3 0.05 0.029126213592233
GO:BP GO:0010647 positive regulation of cell communication 0.0222357840282869 1777 110 20 0.181818181818182 0.0112549240292628
GO:BP GO:0097581 lamellipodium organization 0.0223946451024499 91 136 4 0.0294117647058824 0.043956043956044
GO:BP GO:1902532 negative regulation of intracellular signal transduction 0.0224401866818507 549 12 3 0.25 0.00546448087431694
GO:BP GO:0030595 leukocyte chemotaxis 0.0224401866818507 227 88 5 0.0568181818181818 0.0220264317180617
GO:BP GO:0043085 positive regulation of catalytic activity 0.0227247322746091 1418 110 17 0.154545454545455 0.0119887165021157
GO:BP GO:0032663 regulation of interleukin-2 production 0.0228981614764586 61 104 3 0.0288461538461538 0.0491803278688525
GO:BP GO:0097529 myeloid leukocyte migration 0.0230726877902502 221 130 6 0.0461538461538462 0.0271493212669683
GO:BP GO:0030217 T cell differentiation 0.0233513614219071 260 111 6 0.0540540540540541 0.0230769230769231
GO:BP GO:0002455 humoral immune response mediated by circulating immunoglobulin 0.0234842492383991 156 130 5 0.0384615384615385 0.032051282051282
GO:BP GO:0009892 negative regulation of metabolic process 0.0235959963441471 3479 120 35 0.291666666666667 0.0100603621730382
GO:BP GO:0034381 plasma lipoprotein particle clearance 0.023599484765764 70 92 3 0.0326086956521739 0.0428571428571429
GO:BP GO:0030316 osteoclast differentiation 0.023599484765764 98 130 4 0.0307692307692308 0.0408163265306122
GO:BP GO:0032680 regulation of tumor necrosis factor production 0.0236045627835448 163 125 5 0.04 0.0306748466257669
GO:BP GO:0009056 catabolic process 0.0237841608022091 2744 140 33 0.235714285714286 0.0120262390670554
GO:BP GO:0048872 homeostasis of number of cells 0.0242640096275829 261 79 5 0.0632911392405063 0.0191570881226054
GO:BP GO:0032623 interleukin-2 production 0.0242718255583684 63 104 3 0.0288461538461538 0.0476190476190476
GO:BP GO:0010950 positive regulation of endopeptidase activity 0.0242718255583684 187 110 5 0.0454545454545455 0.0267379679144385
GO:BP GO:0032640 tumor necrosis factor production 0.0243546939475175 165 125 5 0.04 0.0303030303030303
GO:BP GO:0090066 regulation of anatomical structure size 0.0243546939475175 518 136 10 0.0735294117647059 0.0193050193050193
GO:BP GO:0006812 cation transport 0.0243546939475175 1197 131 17 0.129770992366412 0.0142021720969089
GO:BP GO:1990266 neutrophil migration 0.0247034742403693 124 105 4 0.0380952380952381 0.032258064516129
GO:BP GO:1905475 regulation of protein localization to membrane 0.0247034742403693 201 65 4 0.0615384615384615 0.0199004975124378
GO:BP GO:0006412 translation 0.0247034742403693 764 108 11 0.101851851851852 0.0143979057591623
GO:BP GO:0031647 regulation of protein stability 0.0249188666919619 300 130 7 0.0538461538461538 0.0233333333333333
GO:BP GO:0051338 regulation of transferase activity 0.0249691403854982 1035 59 9 0.152542372881356 0.00869565217391304
GO:BP GO:1903555 regulation of tumor necrosis factor superfamily cytokine production 0.025130494117573 167 125 5 0.04 0.029940119760479
GO:BP GO:1905897 regulation of response to endoplasmic reticulum stress 0.0252780178040301 84 80 3 0.0375 0.0357142857142857
GO:BP GO:0030100 regulation of endocytosis 0.025422999253688 212 99 5 0.0505050505050505 0.0235849056603774
GO:BP GO:0043280 positive regulation of cysteine-type endopeptidase activity involved in apoptotic process 0.0257251985470975 138 96 4 0.0416666666666667 0.0289855072463768
GO:BP GO:0010243 response to organonitrogen compound 0.025747730557157 1085 7 3 0.428571428571429 0.00276497695852535
GO:BP GO:0060348 bone development 0.0258543370997345 203 104 5 0.0480769230769231 0.0246305418719212
GO:BP GO:0001776 leukocyte homeostasis 0.0258543370997345 86 79 3 0.0379746835443038 0.0348837209302326
GO:BP GO:0044085 cellular component biogenesis 0.0258543370997345 3257 111 31 0.279279279279279 0.00951796131409272
GO:BP GO:0045859 regulation of protein kinase activity 0.0258543370997345 809 38 6 0.157894736842105 0.00741656365883807
GO:BP GO:1903076 regulation of protein localization to plasma membrane 0.0259865879123634 105 65 3 0.0461538461538462 0.0285714285714286
GO:BP GO:0030335 positive regulation of cell migration 0.0260920190716194 567 107 9 0.0841121495327103 0.0158730158730159
GO:BP GO:2001234 negative regulation of apoptotic signaling pathway 0.026206404119245 236 57 4 0.0701754385964912 0.0169491525423729
GO:BP GO:0071706 tumor necrosis factor superfamily cytokine production 0.026378662428224 170 125 5 0.04 0.0294117647058824
GO:BP GO:0051701 biological process involved in interaction with host 0.0264078267059279 221 61 4 0.0655737704918033 0.0180995475113122
GO:BP GO:0006959 humoral immune response 0.0264078267059279 384 130 8 0.0615384615384615 0.0208333333333333
GO:BP GO:0007167 enzyme linked receptor protein signaling pathway 0.0264078267059279 1103 7 3 0.428571428571429 0.00271985494106981
GO:BP GO:0019674 NAD metabolic process 0.0264090056233956 52 133 3 0.0225563909774436 0.0576923076923077
GO:BP GO:0060402 calcium ion transport into cytosol 0.0264090056233956 165 129 5 0.0387596899224806 0.0303030303030303
GO:BP GO:0035710 CD4-positive, alpha-beta T cell activation 0.0267032407655536 104 130 4 0.0307692307692308 0.0384615384615385
GO:BP GO:0019080 viral gene expression 0.0270336645440768 199 108 5 0.0462962962962963 0.0251256281407035
GO:BP GO:0046907 intracellular transport 0.0273145426661688 1767 99 18 0.181818181818182 0.0101867572156197
GO:BP GO:0010522 regulation of calcium ion transport into cytosol 0.0274817596387622 106 129 4 0.0310077519379845 0.0377358490566038
GO:BP GO:0007163 establishment or maintenance of cell polarity 0.0277265074198095 220 139 6 0.0431654676258993 0.0272727272727273
GO:BP GO:0071621 granulocyte chemotaxis 0.0284287943737771 126 57 3 0.0526315789473684 0.0238095238095238
GO:BP GO:0072593 reactive oxygen species metabolic process 0.0286923116602051 290 140 7 0.05 0.0241379310344828
GO:BP GO:0043043 peptide biosynthetic process 0.0289332551120261 790 108 11 0.101851851851852 0.0139240506329114
GO:BP GO:0002792 negative regulation of peptide secretion 0.0289332551120261 85 85 3 0.0352941176470588 0.0352941176470588
GO:BP GO:1990778 protein localization to cell periphery 0.0290591239495688 338 92 6 0.0652173913043478 0.0177514792899408
GO:BP GO:0043933 protein-containing complex subunit organization 0.0296551651313631 1963 111 21 0.189189189189189 0.010697911360163
GO:BP GO:0016477 cell migration 0.0298170889232988 1649 107 18 0.168224299065421 0.0109157064887811
GO:BP GO:0042093 T-helper cell differentiation 0.0298170889232988 66 111 3 0.027027027027027 0.0454545454545455
GO:BP GO:1901698 response to nitrogen compound 0.0298170889232988 1172 7 3 0.428571428571429 0.00255972696245734
GO:BP GO:0070374 positive regulation of ERK1 and ERK2 cascade 0.0306297999712746 215 104 5 0.0480769230769231 0.0232558139534884
GO:BP GO:1903827 regulation of cellular protein localization 0.0313934881315595 572 130 10 0.0769230769230769 0.0174825174825175
GO:BP GO:0009966 regulation of signal transduction 0.0314704749553408 3165 71 21 0.295774647887324 0.00663507109004739
GO:BP GO:2000147 positive regulation of cell motility 0.0314704749553408 591 107 9 0.0841121495327103 0.0152284263959391
GO:BP GO:0010952 positive regulation of peptidase activity 0.0314704749553408 205 110 5 0.0454545454545455 0.024390243902439
GO:BP GO:0002687 positive regulation of leukocyte migration 0.0314704749553408 137 105 4 0.0380952380952381 0.0291970802919708
GO:BP GO:0051494 negative regulation of cytoskeleton organization 0.0316102969557112 166 136 5 0.0367647058823529 0.0301204819277108
GO:BP GO:0002294 CD4-positive, alpha-beta T cell differentiation involved in immune response 0.0317408040674443 68 111 3 0.027027027027027 0.0441176470588235
GO:BP GO:0043112 receptor metabolic process 0.031775858873893 174 130 5 0.0384615384615385 0.028735632183908
GO:BP GO:0010951 negative regulation of endopeptidase activity 0.0322164124204342 253 126 6 0.0476190476190476 0.0237154150197628
GO:BP GO:0030183 B cell differentiation 0.0325059264852553 140 104 4 0.0384615384615385 0.0285714285714286
GO:BP GO:0007204 positive regulation of cytosolic calcium ion concentration 0.0325777539582974 325 129 7 0.0542635658914729 0.0215384615384615
GO:BP GO:0048869 cellular developmental process 0.0325777539582974 4428 112 39 0.348214285714286 0.00880758807588076
GO:BP GO:0002293 alpha-beta T cell differentiation involved in immune response 0.0326411821819701 69 111 3 0.027027027027027 0.0434782608695652
GO:BP GO:0002287 alpha-beta T cell activation involved in immune response 0.0326411821819701 69 111 3 0.027027027027027 0.0434782608695652
GO:BP GO:0032502 developmental process 0.0327490744084072 6628 59 31 0.525423728813559 0.00467712733856367
GO:BP GO:0014065 phosphatidylinositol 3-kinase signaling 0.032810042464007 161 91 4 0.043956043956044 0.0248447204968944
GO:BP GO:0055082 cellular chemical homeostasis 0.0328868345789145 841 104 11 0.105769230769231 0.0130796670630202
GO:BP GO:0010810 regulation of cell-substrate adhesion 0.032930091240058 222 35 3 0.0857142857142857 0.0135135135135135
GO:BP GO:0060429 epithelium development 0.032930091240058 1325 67 11 0.164179104477612 0.00830188679245283
GO:BP GO:0050672 negative regulation of lymphocyte proliferation 0.0331546710677279 85 91 3 0.032967032967033 0.0352941176470588
GO:BP GO:0002244 hematopoietic progenitor cell differentiation 0.0334638559518197 172 134 5 0.0373134328358209 0.0290697674418605
GO:BP GO:2001056 positive regulation of cysteine-type endopeptidase activity 0.0334844788678478 154 96 4 0.0416666666666667 0.025974025974026
GO:BP GO:0023051 regulation of signaling 0.0334844788678478 3578 104 31 0.298076923076923 0.00866405813303522
GO:BP GO:0043086 negative regulation of catalytic activity 0.0335227076456699 851 39 6 0.153846153846154 0.00705052878965922
GO:BP GO:1902904 negative regulation of supramolecular fiber organization 0.0337441972147989 170 136 5 0.0367647058823529 0.0294117647058824
GO:BP GO:0090316 positive regulation of intracellular protein transport 0.0338861447965596 186 80 4 0.05 0.021505376344086
GO:BP GO:0032945 negative regulation of mononuclear cell proliferation 0.0338896086352104 86 91 3 0.032967032967033 0.0348837209302326
GO:BP GO:0051272 positive regulation of cellular component movement 0.0345136408717837 604 107 9 0.0841121495327103 0.0149006622516556
GO:BP GO:0002576 platelet degranulation 0.0347142496961486 126 119 4 0.0336134453781513 0.0317460317460317
GO:BP GO:0006626 protein targeting to mitochondrion 0.0361111386546347 101 80 3 0.0375 0.0297029702970297
GO:BP GO:0033209 tumor necrosis factor-mediated signaling pathway 0.0362821960392554 177 134 5 0.0373134328358209 0.0282485875706215
GO:BP GO:0002223 stimulatory C-type lectin receptor signaling pathway 0.0365464028568144 112 137 4 0.0291970802919708 0.0357142857142857
GO:BP GO:0019538 protein metabolic process 0.0366579700294412 5808 112 48 0.428571428571429 0.00826446280991736
GO:BP GO:1904375 regulation of protein localization to cell periphery 0.0367863726230826 126 65 3 0.0461538461538462 0.0238095238095238
GO:BP GO:0001932 regulation of protein phosphorylation 0.0370184204035879 1240 93 13 0.139784946236559 0.0104838709677419
GO:BP GO:0060401 cytosolic calcium ion transport 0.0373071812159802 186 129 5 0.0387596899224806 0.0268817204301075
GO:BP GO:0006839 mitochondrial transport 0.0375664022597212 284 85 5 0.0588235294117647 0.0176056338028169
GO:BP GO:0006886 intracellular protein transport 0.0376742652564445 1186 130 16 0.123076923076923 0.0134907251264755
GO:BP GO:0051046 regulation of secretion 0.0376990397992876 647 85 8 0.0941176470588235 0.0123647604327666
GO:BP GO:0002292 T cell differentiation involved in immune response 0.037833435480174 75 111 3 0.027027027027027 0.04
GO:BP GO:0010466 negative regulation of peptidase activity 0.037833435480174 267 126 6 0.0476190476190476 0.0224719101123595
GO:BP GO:0032386 regulation of intracellular transport 0.0378459698439673 367 92 6 0.0652173913043478 0.0163487738419619
GO:BP GO:0016050 vesicle organization 0.0379421533297511 341 99 6 0.0606060606060606 0.0175953079178886
GO:BP GO:0032874 positive regulation of stress-activated MAPK cascade 0.037973660642673 121 69 3 0.0434782608695652 0.0247933884297521
GO:BP GO:1903531 negative regulation of secretion by cell 0.0380463157642421 152 103 4 0.0388349514563107 0.0263157894736842
GO:BP GO:0070664 negative regulation of leukocyte proliferation 0.0382096243806539 92 91 3 0.032967032967033 0.0326086956521739
GO:BP GO:0030154 cell differentiation 0.0383265507734435 4350 112 38 0.339285714285714 0.00873563218390805
GO:BP GO:0002220 innate immune response activating cell surface receptor signaling pathway 0.0387428435439282 115 137 4 0.0291970802919708 0.0347826086956522
GO:BP GO:0002437 inflammatory response to antigenic stimulus 0.0388383166778425 65 130 3 0.0230769230769231 0.0461538461538462
GO:BP GO:0030198 extracellular matrix organization 0.0390301378939551 401 40 4 0.1 0.00997506234413965
GO:BP GO:0070304 positive regulation of stress-activated protein kinase signaling cascade 0.0390402633213595 123 69 3 0.0434782608695652 0.024390243902439
GO:BP GO:0097530 granulocyte migration 0.0390671021041757 151 105 4 0.0380952380952381 0.0264900662251656
GO:BP GO:0043062 extracellular structure organization 0.0391595851698235 402 40 4 0.1 0.00995024875621891
GO:BP GO:0051209 release of sequestered calcium ion into cytosol 0.0391595851698235 123 129 4 0.0310077519379845 0.032520325203252
GO:BP GO:1905477 positive regulation of protein localization to membrane 0.0391921307991475 131 65 3 0.0461538461538462 0.0229007633587786
GO:BP GO:0002758 innate immune response-activating signal transduction 0.0392465417554401 116 137 4 0.0291970802919708 0.0344827586206897
GO:BP GO:0045229 external encapsulating structure organization 0.0396200005060084 404 40 4 0.1 0.0099009900990099
GO:BP GO:0051129 negative regulation of cellular component organization 0.0397213870061565 759 136 12 0.0882352941176471 0.0158102766798419
GO:BP GO:0120034 positive regulation of plasma membrane bounded cell projection assembly 0.0409452857647194 106 82 3 0.0365853658536585 0.0283018867924528
GO:BP GO:2000514 regulation of CD4-positive, alpha-beta T cell activation 0.0410445821694237 67 130 3 0.0230769230769231 0.0447761194029851
GO:BP GO:0045123 cellular extravasation 0.0414121858910132 70 125 3 0.024 0.0428571428571429
GO:BP GO:0050708 regulation of protein secretion 0.0415329461136318 295 85 5 0.0588235294117647 0.0169491525423729
GO:BP GO:0045861 negative regulation of proteolysis 0.0420669986602253 359 126 7 0.0555555555555556 0.0194986072423398
GO:BP GO:0019058 viral life cycle 0.0423290438441934 353 99 6 0.0606060606060606 0.0169971671388102
GO:BP GO:0048864 stem cell development 0.0438763103940722 84 107 3 0.0280373831775701 0.0357142857142857
GO:BP GO:0043488 regulation of mRNA stability 0.0446391441369771 191 134 5 0.0373134328358209 0.0261780104712042
GO:BP GO:1901575 organic substance catabolic process 0.0453457170868778 2267 140 27 0.192857142857143 0.011910013233348
GO:BP GO:0044092 negative regulation of molecular function 0.0454089754341942 1219 39 7 0.179487179487179 0.00574241181296144
GO:BP GO:0002790 peptide secretion 0.0455781484935638 421 85 6 0.0705882352941176 0.0142517814726841
GO:BP GO:0010646 regulation of cell communication 0.0457159987942896 3543 104 30 0.288461538461538 0.00846740050804403
GO:BP GO:0072665 protein localization to vacuole 0.0458021534070651 71 130 3 0.0230769230769231 0.0422535211267606
GO:BP GO:0030837 negative regulation of actin filament polymerization 0.045896556800822 68 136 3 0.0220588235294118 0.0441176470588235
GO:BP GO:0051480 regulation of cytosolic calcium ion concentration 0.0461652366598954 360 129 7 0.0542635658914729 0.0194444444444444
GO:BP GO:0043367 CD4-positive, alpha-beta T cell differentiation 0.0477765711782107 85 111 3 0.027027027027027 0.0352941176470588
GO:BP GO:0051346 negative regulation of hydrolase activity 0.0489784583285066 470 57 5 0.087719298245614 0.0106382978723404
GO:BP GO:0043271 negative regulation of ion transport 0.0497795200225599 349 28 3 0.107142857142857 0.00859598853868195
GO:BP GO:0043604 amide biosynthetic process 0.0497795200225599 932 116 12 0.103448275862069 0.0128755364806867
GO:CC GO:0031982 vesicle 2.73183065080599e-33 4055 140 99 0.707142857142857 0.0244143033292232
GO:CC GO:0070062 extracellular exosome 7.88182380308918e-32 2176 140 75 0.535714285714286 0.0344669117647059
GO:CC GO:0043230 extracellular organelle 5.62021800964152e-31 2263 140 75 0.535714285714286 0.033141847105612
GO:CC GO:1903561 extracellular vesicle 5.62021800964152e-31 2261 140 75 0.535714285714286 0.033171163202123
GO:CC GO:0005615 extracellular space 8.76210365889737e-22 3594 140 80 0.571428571428571 0.0222593210907067
GO:CC GO:0097708 intracellular vesicle 1.04465026949071e-20 2428 140 65 0.464285714285714 0.0267710049423394
GO:CC GO:0031410 cytoplasmic vesicle 1.04465026949071e-20 2424 140 65 0.464285714285714 0.0268151815181518
GO:CC GO:0005576 extracellular region 5.41023125282989e-20 4567 140 87 0.621428571428571 0.0190497044011386
GO:CC GO:0071556 integral component of lumenal side of endoplasmic reticulum membrane 2.03328041791598e-19 25 111 12 0.108108108108108 0.48
GO:CC GO:0098553 lumenal side of endoplasmic reticulum membrane 2.03328041791598e-19 25 111 12 0.108108108108108 0.48
GO:CC GO:0098576 lumenal side of membrane 2.97574992741247e-19 33 120 13 0.108333333333333 0.393939393939394
GO:CC GO:0042611 MHC protein complex 1.54085387124394e-17 24 111 11 0.0990990990990991 0.458333333333333
GO:CC GO:0045335 phagocytic vesicle 7.38412624211899e-13 137 81 13 0.160493827160494 0.0948905109489051
GO:CC GO:0030139 endocytic vesicle 6.33706542554836e-12 306 81 16 0.197530864197531 0.0522875816993464
GO:CC GO:0012507 ER to Golgi transport vesicle membrane 8.12320321905978e-12 57 11 6 0.545454545454545 0.105263157894737
GO:CC GO:0030666 endocytic vesicle membrane 1.47270571590413e-11 159 111 14 0.126126126126126 0.0880503144654088
GO:CC GO:0030176 integral component of endoplasmic reticulum membrane 2.36013551816308e-11 158 116 14 0.120689655172414 0.0886075949367089
GO:CC GO:0042612 MHC class I protein complex 4.1701041382037e-11 8 9 4 0.444444444444444 0.5
GO:CC GO:0031227 intrinsic component of endoplasmic reticulum membrane 4.1701041382037e-11 166 116 14 0.120689655172414 0.0843373493975904
GO:CC GO:0030134 COPII-coated ER to Golgi transport vesicle 1.03750906448314e-10 90 11 6 0.545454545454545 0.0666666666666667
GO:CC GO:0012505 endomembrane system 3.53227095552845e-10 4640 121 64 0.528925619834711 0.0137931034482759
GO:CC GO:0009986 cell surface 4.41794325887107e-10 899 115 26 0.226086956521739 0.0289210233592881
GO:CC GO:0030670 phagocytic vesicle membrane 6.9912128874632e-10 76 81 9 0.111111111111111 0.118421052631579
GO:CC GO:0005773 vacuole 7.72967792054501e-10 810 140 27 0.192857142857143 0.0333333333333333
GO:CC GO:0098552 side of membrane 8.3548598032966e-10 619 120 22 0.183333333333333 0.0355411954765751
GO:CC GO:0000323 lytic vacuole 1.35502542255594e-09 712 140 25 0.178571428571429 0.0351123595505618
GO:CC GO:0005764 lysosome 1.35502542255594e-09 712 140 25 0.178571428571429 0.0351123595505618
GO:CC GO:0030141 secretory granule 2.00965576920142e-09 851 140 27 0.192857142857143 0.0317273795534665
GO:CC GO:0016020 membrane 2.23875749121678e-09 9838 120 96 0.8 0.00975808091075422
GO:CC GO:0005768 endosome 2.50444389713936e-09 987 115 26 0.226086956521739 0.0263424518743668
GO:CC GO:0042613 MHC class II protein complex 4.00293382459745e-09 16 111 6 0.0540540540540541 0.375
GO:CC GO:0030662 coated vesicle membrane 4.00293382459745e-09 177 11 6 0.545454545454545 0.0338983050847458
GO:CC GO:0005774 vacuolar membrane 4.97135829923242e-09 441 120 18 0.15 0.0408163265306122
GO:CC GO:0001772 immunological synapse 6.49520266730875e-09 43 130 8 0.0615384615384615 0.186046511627907
GO:CC GO:0030659 cytoplasmic vesicle membrane 9.58387268642812e-09 779 111 22 0.198198198198198 0.0282413350449294
GO:CC GO:0030658 transport vesicle membrane 9.7015726419797e-09 209 11 6 0.545454545454545 0.0287081339712919
GO:CC GO:0070161 anchoring junction 1.10711197582957e-08 836 105 22 0.20952380952381 0.0263157894736842
GO:CC GO:0012506 vesicle membrane 1.44884420880325e-08 800 111 22 0.198198198198198 0.0275
GO:CC GO:0005925 focal adhesion 1.58958766716427e-08 420 105 16 0.152380952380952 0.0380952380952381
GO:CC GO:0099503 secretory vesicle 1.61708093044773e-08 1020 140 28 0.2 0.0274509803921569
GO:CC GO:0005737 cytoplasm 1.76840847287424e-08 11911 140 120 0.857142857142857 0.0100747208462766
GO:CC GO:0030055 cell-substrate junction 1.87235999475447e-08 427 105 16 0.152380952380952 0.0374707259953162
GO:CC GO:0071944 cell periphery 1.99952151870881e-08 6169 107 65 0.607476635514019 0.0105365537364241
GO:CC GO:0005765 lysosomal membrane 2.72157314246555e-08 383 120 16 0.133333333333333 0.0417754569190601
GO:CC GO:0098852 lytic vacuole membrane 2.72157314246555e-08 383 120 16 0.133333333333333 0.0417754569190601
GO:CC GO:0098588 bounding membrane of organelle 2.73002674494694e-08 2158 106 35 0.330188679245283 0.0162187210379981
GO:CC GO:0030135 coated vesicle 5.88563846902088e-08 295 11 6 0.545454545454545 0.0203389830508475
GO:CC GO:0043227 membrane-bounded organelle 8.33474884161386e-08 12858 140 124 0.885714285714286 0.00964380152434282
GO:CC GO:0031301 integral component of organelle membrane 8.777136858272e-08 382 131 16 0.122137404580153 0.0418848167539267
GO:CC GO:0033290 eukaryotic 48S preinitiation complex 1.48605200191359e-07 15 108 5 0.0462962962962963 0.333333333333333
GO:CC GO:0005886 plasma membrane 1.50363450131458e-07 5681 107 60 0.560747663551402 0.0105615208590037
GO:CC GO:0031300 intrinsic component of organelle membrane 2.46777096850586e-07 413 131 16 0.122137404580153 0.0387409200968523
GO:CC GO:0005852 eukaryotic translation initiation factor 3 complex 2.80974323429022e-07 17 108 5 0.0462962962962963 0.294117647058824
GO:CC GO:0016282 eukaryotic 43S preinitiation complex 2.80974323429022e-07 17 108 5 0.0462962962962963 0.294117647058824
GO:CC GO:0071541 eukaryotic translation initiation factor 3 complex, eIF3m 2.96374081709011e-07 7 108 4 0.037037037037037 0.571428571428571
GO:CC GO:0010008 endosome membrane 3.40618212521289e-07 505 111 16 0.144144144144144 0.0316831683168317
GO:CC GO:0055038 recycling endosome membrane 3.56775359984747e-07 84 9 4 0.444444444444444 0.0476190476190476
GO:CC GO:0070993 translation preinitiation complex 3.56775359984747e-07 18 108 5 0.0462962962962963 0.277777777777778
GO:CC GO:0030133 transport vesicle 3.56775359984747e-07 414 11 6 0.545454545454545 0.0144927536231884
GO:CC GO:0042470 melanosome 4.71205819502741e-07 105 135 9 0.0666666666666667 0.0857142857142857
GO:CC GO:0048770 pigment granule 4.71205819502741e-07 105 135 9 0.0666666666666667 0.0857142857142857
GO:CC GO:0032991 protein-containing complex 6.81272788880592e-07 5548 138 70 0.507246376811594 0.0126171593366979
GO:CC GO:0034774 secretory granule lumen 8.30393049065844e-07 320 140 14 0.1 0.04375
GO:CC GO:0098797 plasma membrane protein complex 8.95733301479943e-07 694 13 7 0.538461538461538 0.0100864553314121
GO:CC GO:0060205 cytoplasmic vesicle lumen 9.37420471224672e-07 324 140 14 0.1 0.0432098765432099
GO:CC GO:0031983 vesicle lumen 9.95524145791382e-07 326 140 14 0.1 0.0429447852760736
GO:CC GO:0005766 primary lysosome 1.51051709970873e-06 154 140 10 0.0714285714285714 0.0649350649350649
GO:CC GO:0042582 azurophil granule 1.51051709970873e-06 154 140 10 0.0714285714285714 0.0649350649350649
GO:CC GO:0031090 organelle membrane 2.38055354736856e-06 3612 125 48 0.384 0.0132890365448505
GO:CC GO:0031226 intrinsic component of plasma membrane 2.38878708109112e-06 1726 52 18 0.346153846153846 0.0104287369640788
GO:CC GO:0015629 actin cytoskeleton 2.58954498733467e-06 513 84 13 0.154761904761905 0.0253411306042885
GO:CC GO:0098796 membrane protein complex 3.48462280703871e-06 1322 111 24 0.216216216216216 0.0181543116490166
GO:CC GO:0031901 early endosome membrane 3.77089057953485e-06 159 9 4 0.444444444444444 0.0251572327044025
GO:CC GO:0005884 actin filament 3.87574920398985e-06 118 79 7 0.0886075949367089 0.0593220338983051
GO:CC GO:0005789 endoplasmic reticulum membrane 4.03658140339669e-06 1117 11 7 0.636363636363636 0.0062667860340197
GO:CC GO:0005770 late endosome 4.03658140339669e-06 275 111 11 0.0990990990990991 0.04
GO:CC GO:0098827 endoplasmic reticulum subcompartment 4.1070436027006e-06 1122 11 7 0.636363636363636 0.00623885918003565
GO:CC GO:0042175 nuclear outer membrane-endoplasmic reticulum membrane network 4.49085663393974e-06 1139 11 7 0.636363636363636 0.00614574187884109
GO:CC GO:0000139 Golgi membrane 4.80276897689521e-06 771 81 15 0.185185185185185 0.0194552529182879
GO:CC GO:0055037 recycling endosome 6.72370568128859e-06 188 9 4 0.444444444444444 0.0212765957446809
GO:CC GO:0097433 dense body 6.89885167994514e-06 6 75 3 0.04 0.5
GO:CC GO:0043226 organelle 9.30213415664798e-06 14008 140 126 0.9 0.00899486007995431
GO:CC GO:0030669 clathrin-coated endocytic vesicle membrane 1.15615612700615e-05 36 111 5 0.045045045045045 0.138888888888889
GO:CC GO:0098791 Golgi apparatus subcompartment 2.11635073835386e-05 885 11 6 0.545454545454545 0.00677966101694915
GO:CC GO:0005887 integral component of plasma membrane 2.62122839695351e-05 1645 52 16 0.307692307692308 0.00972644376899696
GO:CC GO:0005783 endoplasmic reticulum 2.67640448441278e-05 1982 86 24 0.27906976744186 0.012108980827447
GO:CC GO:0005775 vacuolar lumen 3.09240813900992e-05 174 140 9 0.0642857142857143 0.0517241379310345
GO:CC GO:0005794 Golgi apparatus 7.48911326249389e-05 1623 63 17 0.26984126984127 0.0104744300677757
GO:CC GO:0031984 organelle subcompartment 7.48911326249389e-05 1773 11 7 0.636363636363636 0.00394811054709532
GO:CC GO:0045334 clathrin-coated endocytic vesicle 7.97049200777864e-05 54 111 5 0.045045045045045 0.0925925925925926
GO:CC GO:0140534 endoplasmic reticulum protein-containing complex 8.84523681479452e-05 128 121 7 0.0578512396694215 0.0546875
GO:CC GO:0005769 early endosome 8.84523681479452e-05 378 9 4 0.444444444444444 0.0105820105820106
GO:CC GO:0005938 cell cortex 9.01563228132407e-05 311 139 11 0.079136690647482 0.0353697749196141
GO:CC GO:0032588 trans-Golgi network membrane 9.01563228132407e-05 94 111 6 0.0540540540540541 0.0638297872340425
GO:CC GO:1990904 ribonucleoprotein complex 0.000113478968087661 688 118 15 0.127118644067797 0.0218023255813953
GO:CC GO:1904813 ficolin-1-rich granule lumen 0.000126216595061889 124 133 7 0.0526315789473684 0.0564516129032258
GO:CC GO:0030667 secretory granule membrane 0.000151355325024929 303 125 10 0.08 0.033003300330033
GO:CC GO:0043202 lysosomal lumen 0.000159653445269329 97 120 6 0.05 0.0618556701030928
GO:CC GO:0031252 cell leading edge 0.000171656206038447 422 92 10 0.108695652173913 0.023696682464455
GO:CC GO:0101002 ficolin-1-rich granule 0.000210781800532738 184 133 8 0.0601503759398496 0.0434782608695652
GO:CC GO:0035578 azurophil granule lumen 0.000256801718181143 91 140 6 0.0428571428571429 0.0659340659340659
GO:CC GO:0098685 Schaffer collateral - CA1 synapse 0.00039971817936621 80 21 3 0.142857142857143 0.0375
GO:CC GO:0030027 lamellipodium 0.000430690485001787 200 136 8 0.0588235294117647 0.04
GO:CC GO:0030863 cortical cytoskeleton 0.000591326655652537 107 139 6 0.0431654676258993 0.0560747663551402
GO:CC GO:0031224 intrinsic component of membrane 0.000701522541209212 5868 59 32 0.542372881355932 0.005453306066803
GO:CC GO:0031902 late endosome membrane 0.00072578815453877 140 111 6 0.0540540540540541 0.0428571428571429
GO:CC GO:0009897 external side of plasma membrane 0.000785273147661847 408 115 10 0.0869565217391304 0.0245098039215686
GO:CC GO:0030054 cell junction 0.000785273147661847 2105 106 25 0.235849056603774 0.0118764845605701
GO:CC GO:0005811 lipid droplet 0.000785273147661847 95 106 5 0.0471698113207547 0.0526315789473684
GO:CC GO:0031904 endosome lumen 0.000812480026793871 35 62 3 0.0483870967741935 0.0857142857142857
GO:CC GO:0005829 cytosol 0.000817496144298051 5303 137 58 0.423357664233577 0.0109372053554592
GO:CC GO:0005793 endoplasmic reticulum-Golgi intermediate compartment 0.000914650228831971 131 80 5 0.0625 0.0381679389312977
GO:CC GO:0016021 integral component of membrane 0.00102292764177353 5711 59 31 0.525423728813559 0.00542812116967256
GO:CC GO:0072562 blood microparticle 0.0011517532658254 140 18 3 0.166666666666667 0.0214285714285714
GO:CC GO:0030665 clathrin-coated vesicle membrane 0.00210668549542469 114 111 5 0.045045045045045 0.043859649122807
GO:CC GO:0005771 multivesicular body 0.00269479229161979 62 54 3 0.0555555555555556 0.0483870967741935
GO:CC GO:0070820 tertiary granule 0.00271200064614155 163 125 6 0.048 0.0368098159509202
GO:CC GO:0062023 collagen-containing extracellular matrix 0.00282443068813137 421 133 10 0.075187969924812 0.0237529691211401
GO:CC GO:0005622 intracellular anatomical structure 0.00323997941113846 14790 140 124 0.885714285714286 0.00838404327248141
GO:CC GO:0030136 clathrin-coated vesicle 0.00337732287224739 193 111 6 0.0540540540540541 0.0310880829015544
GO:CC GO:0043229 intracellular organelle 0.00454407249986494 12491 140 109 0.778571428571429 0.00872628292370507
GO:CC GO:0005911 cell-cell junction 0.00490481747622863 494 103 9 0.087378640776699 0.0182186234817814
GO:CC GO:0005856 cytoskeleton 0.00541136142826753 2332 20 8 0.4 0.00343053173241852
GO:CC GO:0099513 polymeric cytoskeletal fiber 0.00655660634505544 764 7 3 0.428571428571429 0.00392670157068063
GO:CC GO:1904724 tertiary granule lumen 0.00750333446984034 55 91 3 0.032967032967033 0.0545454545454545
GO:CC GO:0005791 rough endoplasmic reticulum 0.00893776289548766 86 62 3 0.0483870967741935 0.0348837209302326
GO:CC GO:0005802 trans-Golgi network 0.011188884295884 250 111 6 0.0540540540540541 0.024
GO:CC GO:0035577 azurophil granule membrane 0.011560664385832 57 103 3 0.029126213592233 0.0526315789473684
GO:CC GO:0033116 endoplasmic reticulum-Golgi intermediate compartment membrane 0.0117126880326048 74 80 3 0.0375 0.0405405405405405
GO:CC GO:0099512 supramolecular fiber 0.0131610485630256 993 7 3 0.428571428571429 0.00302114803625378
GO:CC GO:0042581 specific granule 0.0133285969205862 158 128 5 0.0390625 0.0316455696202532
GO:CC GO:0099081 supramolecular polymer 0.0133285969205862 1001 7 3 0.428571428571429 0.002997002997003
GO:CC GO:1905368 peptidase complex 0.0144880233447465 96 134 4 0.0298507462686567 0.0416666666666667
GO:CC GO:0031012 extracellular matrix 0.0182507530527403 562 133 10 0.075187969924812 0.0177935943060498
GO:CC GO:0030312 external encapsulating structure 0.0183095218202363 563 133 10 0.075187969924812 0.0177619893428064
GO:CC GO:0043231 intracellular membrane-bounded organelle 0.0188444214114674 11296 97 70 0.721649484536082 0.00619688385269122
GO:CC GO:0005903 brush border 0.0206214400164671 107 136 4 0.0294117647058824 0.0373831775700935
GO:CC GO:0099080 supramolecular complex 0.0261152628473741 1323 7 3 0.428571428571429 0.00226757369614512
GO:CC GO:0098857 membrane microdomain 0.027354807393694 335 104 6 0.0576923076923077 0.017910447761194
GO:CC GO:0045121 membrane raft 0.027354807393694 335 104 6 0.0576923076923077 0.017910447761194
GO:CC GO:0043005 neuron projection 0.0279191564941852 1380 7 3 0.428571428571429 0.00217391304347826
GO:CC GO:0030496 midbody 0.0334580942463311 196 135 5 0.037037037037037 0.0255102040816327
GO:CC GO:0009898 cytoplasmic side of plasma membrane 0.0343564608186487 168 104 4 0.0384615384615385 0.0238095238095238
GO:CC GO:1905369 endopeptidase complex 0.0356502091222575 72 134 3 0.0223880597014925 0.0416666666666667
GO:CC GO:0048471 perinuclear region of cytoplasm 0.0391856830856518 735 101 9 0.0891089108910891 0.0122448979591837
GO:CC GO:0019898 extrinsic component of membrane 0.0426974144121124 313 92 5 0.0543478260869565 0.0159744408945687
GO:CC GO:0016323 basolateral plasma membrane 0.0432533964594121 222 130 5 0.0384615384615385 0.0225225225225225
GO:CC GO:0030864 cortical actin cytoskeleton 0.0467057046794001 79 139 3 0.0215827338129496 0.0379746835443038
GO:CC GO:0043235 receptor complex 0.0488078575153004 522 39 4 0.102564102564103 0.00766283524904215
GO:CC GO:0098562 cytoplasmic side of membrane 0.0492361305181664 194 104 4 0.0384615384615385 0.0206185567010309
GO:MF GO:0042605 peptide antigen binding 5.24007298376214e-13 30 111 10 0.0900900900900901 0.333333333333333
GO:MF GO:0044877 protein-containing complex binding 6.12489239849373e-13 1287 138 40 0.289855072463768 0.0310800310800311
GO:MF GO:0046977 TAP binding 2.97319661447038e-08 9 81 5 0.0617283950617284 0.555555555555556
GO:MF GO:0003823 antigen binding 3.22113945218908e-08 163 111 12 0.108108108108108 0.0736196319018405
GO:MF GO:0023026 MHC class II protein complex binding 1.43234189187926e-07 17 133 6 0.0451127819548872 0.352941176470588
GO:MF GO:0050839 cell adhesion molecule binding 4.13419378366447e-07 546 140 20 0.142857142857143 0.0366300366300366
GO:MF GO:0042277 peptide binding 7.0188482916282e-07 314 11 6 0.545454545454545 0.0191082802547771
GO:MF GO:0023023 MHC protein complex binding 1.22256153399887e-06 25 133 6 0.0451127819548872 0.24
GO:MF GO:0033218 amide binding 1.95747410868608e-06 389 11 6 0.545454545454545 0.0154241645244216
GO:MF GO:0045296 cadherin binding 1.14131002288966e-05 333 140 14 0.1 0.042042042042042
GO:MF GO:0042608 T cell receptor binding 1.81971930744002e-05 11 111 4 0.036036036036036 0.363636363636364
GO:MF GO:0005515 protein binding 1.98984112784473e-05 14767 140 132 0.942857142857143 0.00893885013882305
GO:MF GO:0030881 beta-2-microglobulin binding 0.000102845814870926 7 81 3 0.037037037037037 0.428571428571429
GO:MF GO:0005200 structural constituent of cytoskeleton 0.000114629856600305 104 73 6 0.0821917808219178 0.0576923076923077
GO:MF GO:0042287 MHC protein binding 0.000224566577798951 39 130 5 0.0384615384615385 0.128205128205128
GO:MF GO:0042609 CD4 receptor binding 0.000244959328651473 9 88 3 0.0340909090909091 0.333333333333333
GO:MF GO:0032395 MHC class II receptor activity 0.000296728316486974 8 111 3 0.027027027027027 0.375
GO:MF GO:0003779 actin binding 0.000431788608118349 448 79 10 0.126582278481013 0.0223214285714286
GO:MF GO:0140375 immune receptor activity 0.000431788608118349 133 115 7 0.0608695652173913 0.0526315789473684
GO:MF GO:0003743 translation initiation factor activity 0.000467160071105639 58 108 5 0.0462962962962963 0.0862068965517241
GO:MF GO:0008135 translation factor activity, RNA binding 0.000499428007014751 99 108 6 0.0555555555555556 0.0606060606060606
GO:MF GO:0045182 translation regulator activity 0.00064734426532032 155 108 7 0.0648148148148148 0.0451612903225806
GO:MF GO:0090079 translation regulator activity, nucleic acid binding 0.00144627449912188 123 108 6 0.0555555555555556 0.0487804878048781
GO:MF GO:0042288 MHC class I protein binding 0.00144627449912188 20 80 3 0.0375 0.15
GO:MF GO:0043236 laminin binding 0.00175194904334552 28 61 3 0.0491803278688525 0.107142857142857
GO:MF GO:0044548 S100 protein binding 0.00179399044769458 14 128 3 0.0234375 0.214285714285714
GO:MF GO:0050840 extracellular matrix binding 0.00259547159870017 56 92 4 0.0434782608695652 0.0714285714285714
GO:MF GO:0051015 actin filament binding 0.00259547159870017 212 136 8 0.0588235294117647 0.0377358490566038
GO:MF GO:0030234 enzyme regulator activity 0.00377023930620884 1248 126 20 0.158730158730159 0.016025641025641
GO:MF GO:0060089 molecular transducer activity 0.00681901871373319 1458 59 13 0.220338983050847 0.00891632373113855
GO:MF GO:0038023 signaling receptor activity 0.00681901871373319 1458 59 13 0.220338983050847 0.00891632373113855
GO:MF GO:0003723 RNA binding 0.00681901871373319 1943 133 27 0.203007518796992 0.0138960370560988
GO:MF GO:0042802 identical protein binding 0.00681905306447309 2067 65 17 0.261538461538462 0.00822447992259313
GO:MF GO:0061134 peptidase regulator activity 0.00945946705221492 224 126 7 0.0555555555555556 0.03125
GO:MF GO:0043022 ribosome binding 0.0106706271042534 59 61 3 0.0491803278688525 0.0508474576271186
GO:MF GO:0004857 enzyme inhibitor activity 0.0112516047743924 385 38 5 0.131578947368421 0.012987012987013
GO:MF GO:0008092 cytoskeletal protein binding 0.0118059359718491 996 139 17 0.122302158273381 0.0170682730923695
GO:MF GO:0005198 structural molecule activity 0.015662285584703 698 7 3 0.428571428571429 0.00429799426934097
GO:MF GO:0061135 endopeptidase regulator activity 0.0165014301536744 188 126 6 0.0476190476190476 0.0319148936170213
GO:MF GO:0008047 enzyme activator activity 0.0171345354549645 540 78 8 0.102564102564103 0.0148148148148148
GO:MF GO:0043028 cysteine-type endopeptidase regulator activity involved in apoptotic process 0.0186455301675413 38 126 3 0.0238095238095238 0.0789473684210526
GO:MF GO:0043021 ribonucleoprotein complex binding 0.0186455301675413 137 75 4 0.0533333333333333 0.0291970802919708
GO:MF GO:0019904 protein domain specific binding 0.0186455301675413 710 137 13 0.0948905109489051 0.0183098591549296
GO:MF GO:0005102 signaling receptor binding 0.0192369887655214 1672 113 20 0.176991150442478 0.0119617224880383
GO:MF GO:0048306 calcium-dependent protein binding 0.0192818323741541 82 128 4 0.03125 0.0487804878048781
GO:MF GO:0001540 amyloid-beta binding 0.0206556731038714 83 62 3 0.0483870967741935 0.036144578313253
GO:MF GO:0015485 cholesterol binding 0.0350229392376639 50 130 3 0.0230769230769231 0.06
GO:MF GO:0030246 carbohydrate binding 0.0384929727073749 275 113 6 0.0530973451327434 0.0218181818181818
GO:MF GO:0098631 cell adhesion mediator activity 0.0384929727073749 58 125 3 0.024 0.0517241379310345
GO:MF GO:0098772 molecular function regulator 0.0384929727073749 2363 112 24 0.214285714285714 0.0101565806178587
GO:MF GO:0004866 endopeptidase inhibitor activity 0.0384929727073749 176 126 5 0.0396825396825397 0.0284090909090909
GO:MF GO:0019899 enzyme binding 0.0384929727073749 2074 12 5 0.416666666666667 0.00241080038572806
GO:MF GO:0019887 protein kinase regulator activity 0.0384929727073749 191 38 3 0.0789473684210526 0.0157068062827225
GO:MF GO:0005544 calcium-dependent phospholipid binding 0.0384929727073749 54 128 3 0.0234375 0.0555555555555556
GO:MF GO:0030414 peptidase inhibitor activity 0.0421441986521587 182 126 5 0.0396825396825397 0.0274725274725275
GO:MF GO:0032934 sterol binding 0.0443294483257662 60 130 3 0.0230769230769231 0.05
GO:MF GO:0016627 oxidoreductase activity, acting on the CH-CH group of donors 0.0449285301454747 65 123 3 0.024390243902439 0.0461538461538462
GO:MF GO:0003924 GTPase activity 0.0465273335363133 328 103 6 0.058252427184466 0.0182926829268293
GO:MF GO:0019207 kinase regulator activity 0.0469784580188955 221 38 3 0.0789473684210526 0.0135746606334842
HP HP:0002637 Cerebral ischemia 0.0120103466862764 99 8 4 0.5 0.0404040404040404
HP HP:0033401 Tissue ischemia 0.0120103466862764 99 8 4 0.5 0.0404040404040404
HP HP:0025323 Abnormal arterial physiology 0.0173606727690899 130 8 4 0.5 0.0307692307692308
HP HP:0010885 Avascular necrosis 0.024149024350861 73 6 3 0.5 0.0410958904109589
HP HP:0100539 Periorbital edema 0.0326571076331493 60 8 3 0.375 0.05
HP HP:0000282 Facial edema 0.0385704738567393 69 8 3 0.375 0.0434782608695652
HP HP:0001287 Meningitis 0.0427614341532201 72 59 6 0.101694915254237 0.0833333333333333
HPA HPA:0530722 spleen; cells in white pulp[≥Medium] 2.65421582740876e-11 2645 123 69 0.560975609756098 0.0260869565217391
HPA HPA:0600443 tonsil; non-germinal center cells[High] 1.28778227266781e-10 1271 119 44 0.369747899159664 0.034618410700236
HPA HPA:0030073 appendix; lymphoid tissue[High] 1.28778227266781e-10 803 119 35 0.294117647058824 0.0435865504358655
HPA HPA:0310433 lymph node; germinal center cells[High] 5.07424135673166e-10 908 119 36 0.302521008403361 0.039647577092511
HPA HPA:0310443 lymph node; non-germinal center cells[High] 1.89073747111405e-09 1169 119 40 0.336134453781513 0.0342172797262618
HPA HPA:0310442 lymph node; non-germinal center cells[≥Medium] 3.38230931467796e-09 3875 123 80 0.650406504065041 0.0206451612903226
HPA HPA:0530723 spleen; cells in white pulp[High] 7.13192066073937e-09 811 119 32 0.26890756302521 0.0394574599260173
HPA HPA:0530721 spleen; cells in white pulp[≥Low] 1.2684448085223e-08 4249 123 83 0.67479674796748 0.0195340080018828
HPA HPA:0600442 tonsil; non-germinal center cells[≥Medium] 1.2684448085223e-08 4079 123 81 0.658536585365854 0.0198578082863447
HPA HPA:0530712 spleen; cells in red pulp[≥Medium] 4.68048121037473e-08 3049 121 66 0.545454545454545 0.0216464414562152
HPA HPA:0030072 appendix; lymphoid tissue[≥Medium] 2.20410958225457e-07 3131 122 66 0.540983606557377 0.0210795273075695
HPA HPA:0600433 tonsil; germinal center cells[High] 9.29406453264629e-07 1179 119 35 0.294117647058824 0.0296861747243427
HPA HPA:0530711 spleen; cells in red pulp[≥Low] 4.02855913913542e-06 5195 123 88 0.715447154471545 0.016939364773821
HPA HPA:0040083 bone marrow; hematopoietic cells[High] 4.06550748714492e-06 1376 105 34 0.323809523809524 0.0247093023255814
HPA HPA:0600432 tonsil; germinal center cells[≥Medium] 1.09731926587031e-05 3988 123 73 0.59349593495935 0.0183049147442327
HPA HPA:0530713 spleen; cells in red pulp[High] 3.33668076857456e-05 778 105 23 0.219047619047619 0.0295629820051414
HPA HPA:0310441 lymph node; non-germinal center cells[≥Low] 3.98094794201742e-05 5915 123 93 0.75609756097561 0.0157227387996619
HPA HPA:0530000 spleen 5.21476545001594e-05 5756 123 91 0.739837398373984 0.0158095899930507
HPA HPA:0040082 bone marrow; hematopoietic cells[≥Medium] 9.59654237544412e-05 4126 121 71 0.586776859504132 0.0172079495879787
HPA HPA:0600441 tonsil; non-germinal center cells[≥Low] 0.000139007472527672 5966 123 92 0.747967479674797 0.015420717398592
HPA HPA:0040000 bone marrow 0.000288514171059294 6349 123 95 0.772357723577236 0.0149629862970547
HPA HPA:0040081 bone marrow; hematopoietic cells[≥Low] 0.000288514171059294 6349 123 95 0.772357723577236 0.0149629862970547
HPA HPA:0030071 appendix; lymphoid tissue[≥Low] 0.000344402330388434 4976 123 80 0.650406504065041 0.0160771704180064
HPA HPA:0310432 lymph node; germinal center cells[≥Medium] 0.000344402330388434 3209 121 58 0.479338842975207 0.0180741664069804
HPA HPA:0310431 lymph node; germinal center cells[≥Low] 0.000608529332403286 4935 140 88 0.628571428571429 0.0178318135764944
HPA HPA:0310000 lymph node 0.000714980463748059 6374 123 94 0.764227642276423 0.0147474113586445
HPA HPA:0300413 lung; macrophages[High] 0.00147083396863706 1224 123 29 0.235772357723577 0.0236928104575163
HPA HPA:0320842 nasopharynx; basal cells[≥Medium] 0.0213840882670974 288 120 10 0.0833333333333333 0.0347222222222222
HPA HPA:0211092 fallopian tube; non-ciliated cells[≥Medium] 0.0220934680214787 328 125 11 0.088 0.0335365853658537
HPA HPA:0170053 endometrium 2; glandular cells[High] 0.0229242188291232 1282 120 26 0.216666666666667 0.0202808112324493
HPA HPA:0600431 tonsil; germinal center cells[≥Low] 0.0229242188291232 5845 111 76 0.684684684684685 0.0130025662959795
HPA HPA:0211091 fallopian tube; non-ciliated cells[≥Low] 0.0324532970277933 456 125 13 0.104 0.0285087719298246
HPA HPA:0320841 nasopharynx; basal cells[≥Low] 0.0360415940640475 370 120 11 0.0916666666666667 0.0297297297297297
HPA HPA:0091072 cerebellum; white matter cells - cytoplasm/membrane[≥Medium] 0.0435351115686609 225 119 8 0.0672268907563025 0.0355555555555556
HPA HPA:0091003 cerebellum; molecular layer cells - cytoplasm/membrane[High] 0.0482131822085438 182 119 7 0.0588235294117647 0.0384615384615385
HPA HPA:0090972 cerebellum; granular cells - cytoplasm/membrane[≥Medium] 0.0482131822085438 231 119 8 0.0672268907563025 0.0346320346320346
HPA HPA:0170252 endometrium 2; cells in endometrial stroma[≥Medium] 0.0493607767142488 1722 121 31 0.256198347107438 0.0180023228803717
KEGG KEGG:05416 Viral myocarditis 3.83780399629224e-12 56 9 7 0.777777777777778 0.125
KEGG KEGG:04612 Antigen processing and presentation 3.34956478278558e-11 69 111 14 0.126126126126126 0.202898550724638
KEGG KEGG:04145 Phagosome 1.03219541499711e-09 147 9 7 0.777777777777778 0.0476190476190476
KEGG KEGG:05330 Allograft rejection 1.03219541499711e-09 34 111 10 0.0900900900900901 0.294117647058824
KEGG KEGG:05332 Graft-versus-host disease 1.72168112757861e-09 37 111 10 0.0900900900900901 0.27027027027027
KEGG KEGG:04940 Type I diabetes mellitus 3.37239880494816e-09 40 111 10 0.0900900900900901 0.25
KEGG KEGG:05320 Autoimmune thyroid disease 2.38326761315781e-08 49 9 5 0.555555555555556 0.102040816326531
KEGG KEGG:04514 Cell adhesion molecules 2.69997864922031e-07 146 111 14 0.126126126126126 0.0958904109589041
KEGG KEGG:05169 Epstein-Barr virus infection 3.60773144168796e-07 198 9 6 0.666666666666667 0.0303030303030303
KEGG KEGG:05166 Human T-cell leukemia virus 1 infection 3.04912520691034e-05 216 9 5 0.555555555555556 0.0231481481481481
KEGG KEGG:04672 Intestinal immune network for IgA production 4.21628490032171e-05 45 111 7 0.0630630630630631 0.155555555555556
KEGG KEGG:04650 Natural killer cell mediated cytotoxicity 0.000101564610722905 123 9 4 0.444444444444444 0.032520325203252
KEGG KEGG:04218 Cellular senescence 0.000232731040834118 156 9 4 0.444444444444444 0.0256410256410256
KEGG KEGG:04670 Leukocyte transendothelial migration 0.000232731040834118 114 105 9 0.0857142857142857 0.0789473684210526
KEGG KEGG:05168 Herpes simplex virus 1 infection 0.000244763749377091 494 11 6 0.545454545454545 0.0121457489878543
KEGG KEGG:05310 Asthma 0.000358385462231207 27 111 5 0.045045045045045 0.185185185185185
KEGG KEGG:05167 Kaposi sarcoma-associated herpesvirus infection 0.000427053813432499 193 9 4 0.444444444444444 0.0207253886010363
KEGG KEGG:05203 Viral carcinogenesis 0.000482454851322449 202 9 4 0.444444444444444 0.0198019801980198
KEGG KEGG:05170 Human immunodeficiency virus 1 infection 0.000532324636331623 210 9 4 0.444444444444444 0.019047619047619
KEGG KEGG:05140 Leishmaniasis 0.000553343467613485 72 111 7 0.0630630630630631 0.0972222222222222
KEGG KEGG:05163 Human cytomegalovirus infection 0.000609409523204363 223 9 4 0.444444444444444 0.0179372197309417
KEGG KEGG:04144 Endocytosis 0.000937608533421924 252 9 4 0.444444444444444 0.0158730158730159
KEGG KEGG:05165 Human papillomavirus infection 0.000964907045395139 331 13 5 0.384615384615385 0.0151057401812689
KEGG KEGG:04810 Regulation of actin cytoskeleton 0.00122558900911411 216 20 5 0.25 0.0231481481481481
KEGG KEGG:05412 Arrhythmogenic right ventricular cardiomyopathy 0.00176558050620601 77 13 3 0.230769230769231 0.038961038961039
KEGG KEGG:05321 Inflammatory bowel disease 0.00183292237480099 62 115 6 0.0521739130434783 0.0967741935483871
KEGG KEGG:05130 Pathogenic Escherichia coli infection 0.0019600955106214 196 6 3 0.5 0.0153061224489796
KEGG KEGG:04510 Focal adhesion 0.00214726807673314 200 14 4 0.285714285714286 0.02
KEGG KEGG:04640 Hematopoietic cell lineage 0.00220385092936317 95 111 7 0.0630630630630631 0.0736842105263158
KEGG KEGG:05410 Hypertrophic cardiomyopathy 0.00232702719023481 90 13 3 0.230769230769231 0.0333333333333333
KEGG KEGG:04530 Tight junction 0.00232702719023481 169 84 8 0.0952380952380952 0.0473372781065089
KEGG KEGG:05414 Dilated cardiomyopathy 0.00256619898121764 95 13 3 0.230769230769231 0.0315789473684211
KEGG KEGG:05164 Influenza A 0.00280460629507248 169 8 3 0.375 0.0177514792899408
KEGG KEGG:05100 Bacterial invasion of epithelial cells 0.00360048516236439 77 73 5 0.0684931506849315 0.0649350649350649
KEGG KEGG:05152 Tuberculosis 0.00372744926129371 175 111 9 0.0810810810810811 0.0514285714285714
KEGG KEGG:05131 Shigellosis 0.00545171364230006 246 84 9 0.107142857142857 0.0365853658536585
KEGG KEGG:04611 Platelet activation 0.00577670048740969 124 14 3 0.214285714285714 0.0241935483870968
KEGG KEGG:05323 Rheumatoid arthritis 0.00631168338238547 88 111 6 0.0540540540540541 0.0681818181818182
KEGG KEGG:05132 Salmonella infection 0.00653533718235057 249 104 10 0.0961538461538462 0.0401606425702811
KEGG KEGG:04658 Th1 and Th2 cell differentiation 0.00765450595720249 89 115 6 0.0521739130434783 0.0674157303370786
KEGG KEGG:04962 Vasopressin-regulated water reabsorption 0.00770291954483709 44 44 3 0.0681818181818182 0.0681818181818182
KEGG KEGG:05340 Primary immunodeficiency 0.00795745478580276 37 115 4 0.0347826086956522 0.108108108108108
KEGG KEGG:05135 Yersinia infection 0.0116597243032831 136 35 4 0.114285714285714 0.0294117647058824
KEGG KEGG:04142 Lysosome 0.0124546095702618 128 120 7 0.0583333333333333 0.0546875
KEGG KEGG:04659 Th17 cell differentiation 0.0147442916187962 104 115 6 0.0521739130434783 0.0576923076923077
KEGG KEGG:05150 Staphylococcus aureus infection 0.0247049914994018 87 111 5 0.045045045045045 0.0574712643678161
KEGG KEGG:04666 Fc gamma R-mediated phagocytosis 0.02739106381228 96 104 5 0.0480769230769231 0.0520833333333333
MIRNA MIRNA:hsa-miR-615-3p hsa-miR-615-3p 0.00256686070071842 891 118 22 0.186440677966102 0.0246913580246914
MIRNA MIRNA:hsa-miR-326 hsa-miR-326 0.0107489114529329 136 6 3 0.5 0.0220588235294118
MIRNA MIRNA:hsa-miR-23b-3p hsa-miR-23b-3p 0.0311254036396257 319 139 11 0.079136690647482 0.0344827586206897
MIRNA MIRNA:hsa-miR-324-3p hsa-miR-324-3p 0.0311254036396257 336 136 11 0.0808823529411765 0.0327380952380952
REAC REAC:R-HSA-1236977 Endosomal/Vacuolar pathway 4.16851120594278e-08 11 81 6 0.0740740740740741 0.545454545454545
REAC REAC:R-HSA-983170 Antigen Presentation: Folding, assembly and peptide loading of class I MHC 1.42439556688129e-07 25 81 7 0.0864197530864197 0.28
REAC REAC:R-HSA-168256 Immune System 1.64560993485276e-07 2139 140 60 0.428571428571429 0.0280504908835905
REAC REAC:R-HSA-877300 Interferon gamma signaling 2.08677375876524e-07 87 111 11 0.0990990990990991 0.126436781609195
REAC REAC:R-HSA-1280215 Cytokine Signaling in Immune system 1.04736841035534e-06 842 9 8 0.888888888888889 0.00950118764845606
REAC REAC:R-HSA-168249 Innate Immune System 1.04736841035534e-06 1073 140 38 0.271428571428571 0.0354147250698975
REAC REAC:R-HSA-6798695 Neutrophil degranulation 1.04736841035534e-06 474 140 24 0.171428571428571 0.0506329113924051
REAC REAC:R-HSA-1280218 Adaptive Immune System 6.14967077610314e-06 800 137 30 0.218978102189781 0.0375
REAC REAC:R-HSA-909733 Interferon alpha/beta signaling 1.04579724486684e-05 66 9 4 0.444444444444444 0.0606060606060606
REAC REAC:R-HSA-913531 Interferon Signaling 1.20136363506793e-05 191 9 5 0.555555555555556 0.0261780104712042
REAC REAC:R-HSA-1236974 ER-Phagosome pathway 2.13134506932884e-05 83 9 4 0.444444444444444 0.0481927710843374
REAC REAC:R-HSA-1236975 Antigen processing-Cross presentation 2.13134506932884e-05 99 134 10 0.0746268656716418 0.101010101010101
REAC REAC:R-HSA-72695 Formation of the ternary complex, and subsequently, the 43S complex 3.74214669949583e-05 52 108 7 0.0648148148148148 0.134615384615385
REAC REAC:R-HSA-198933 Immunoregulatory interactions between a Lymphoid and a non-Lymphoid cell 6.33566025108021e-05 181 13 5 0.384615384615385 0.0276243093922652
REAC REAC:R-HSA-72702 Ribosomal scanning and start codon recognition 7.31045654332301e-05 59 108 7 0.0648148148148148 0.11864406779661
REAC REAC:R-HSA-72649 Translation initiation complex formation 7.31045654332301e-05 59 108 7 0.0648148148148148 0.11864406779661
REAC REAC:R-HSA-72662 Activation of the mRNA upon binding of the cap-binding complex and eIFs, and subsequent binding to 43S 7.72402236554344e-05 60 108 7 0.0648148148148148 0.116666666666667
REAC REAC:R-HSA-202427 Phosphorylation of CD3 and TCR zeta chains 0.000103686177938738 23 111 5 0.045045045045045 0.217391304347826
REAC REAC:R-HSA-389948 PD-1 signaling 0.000123041758511488 24 111 5 0.045045045045045 0.208333333333333
REAC REAC:R-HSA-6802948 Signaling by high-kinase activity BRAF mutants 0.000189291991772138 35 38 4 0.105263157894737 0.114285714285714
REAC REAC:R-HSA-5674135 MAP2K and MAPK activation 0.000261610547861051 39 12 3 0.25 0.0769230769230769
REAC REAC:R-HSA-6802946 Signaling by moderate kinase activity BRAF mutants 0.000326823654608285 45 12 3 0.25 0.0666666666666667
REAC REAC:R-HSA-9649948 Signaling downstream of RAS mutants 0.000326823654608285 45 12 3 0.25 0.0666666666666667
REAC REAC:R-HSA-6802955 Paradoxical activation of RAF signaling by kinase inactive BRAF 0.000326823654608285 45 12 3 0.25 0.0666666666666667
REAC REAC:R-HSA-6802949 Signaling by RAS mutants 0.000326823654608285 45 12 3 0.25 0.0666666666666667
REAC REAC:R-HSA-2682334 EPH-Ephrin signaling 0.000422580896523165 90 20 4 0.2 0.0444444444444444
REAC REAC:R-HSA-2132295 MHC class II antigen presentation 0.000542169494759341 123 136 9 0.0661764705882353 0.0731707317073171
REAC REAC:R-HSA-6802952 Signaling by BRAF and RAF fusions 0.000647451839481201 64 103 6 0.058252427184466 0.09375
REAC REAC:R-HSA-5663213 RHO GTPases Activate WASPs and WAVEs 0.000647451839481201 35 20 3 0.15 0.0857142857142857
REAC REAC:R-HSA-202430 Translocation of ZAP-70 to Immunological synapse 0.000819167601879017 20 111 4 0.036036036036036 0.2
REAC REAC:R-HSA-3928662 EPHB-mediated forward signaling 0.000885746945718169 40 20 3 0.15 0.075
REAC REAC:R-HSA-72689 Formation of a pool of free 40S subunits 0.00126133382345593 102 108 7 0.0648148148148148 0.0686274509803922
REAC REAC:R-HSA-6802957 Oncogenic MAPK signaling 0.00143855061208469 82 12 3 0.25 0.0365853658536585
REAC REAC:R-HSA-156827 L13a-mediated translational silencing of Ceruloplasmin expression 0.00199128410430455 112 108 7 0.0648148148148148 0.0625
REAC REAC:R-HSA-72706 GTP hydrolysis and joining of the 60S ribosomal subunit 0.00205375307988381 113 108 7 0.0648148148148148 0.0619469026548673
REAC REAC:R-HSA-983169 Class I MHC mediated antigen processing & presentation 0.00208199015617132 370 9 4 0.444444444444444 0.0108108108108108
REAC REAC:R-HSA-202403 TCR signaling 0.00208199015617132 120 137 8 0.0583941605839416 0.0666666666666667
REAC REAC:R-HSA-72766 Translation 0.00239940335441781 292 108 11 0.101851851851852 0.0376712328767123
REAC REAC:R-HSA-72613 Eukaryotic Translation Initiation 0.00260265699179253 120 108 7 0.0648148148148148 0.0583333333333333
REAC REAC:R-HSA-72737 Cap-dependent Translation Initiation 0.00260265699179253 120 108 7 0.0648148148148148 0.0583333333333333
REAC REAC:R-HSA-202424 Downstream TCR signaling 0.00315781858600842 98 137 7 0.0510948905109489 0.0714285714285714
REAC REAC:R-HSA-445355 Smooth Muscle Contraction 0.00335395716878994 38 92 4 0.0434782608695652 0.105263157894737
REAC REAC:R-HSA-879415 Advanced glycosylation endproduct receptor signaling 0.00392076714689876 13 121 3 0.0247933884297521 0.230769230769231
REAC REAC:R-HSA-202433 Generation of second messenger molecules 0.00470364319986909 35 111 4 0.036036036036036 0.114285714285714
REAC REAC:R-HSA-388841 Costimulation by the CD28 family 0.00639298364159612 67 111 5 0.045045045045045 0.0746268656716418
REAC REAC:R-HSA-9664417 Leishmania phagocytosis 0.0103705833510286 113 20 3 0.15 0.0265486725663717
REAC REAC:R-HSA-9664407 Parasite infection 0.0103705833510286 113 20 3 0.15 0.0265486725663717
REAC REAC:R-HSA-9664422 FCGR3A-mediated phagocytosis 0.0103705833510286 113 20 3 0.15 0.0265486725663717
REAC REAC:R-HSA-2029482 Regulation of actin dynamics for phagocytic cup formation 0.0110110624135081 116 20 3 0.15 0.0258620689655172
REAC REAC:R-HSA-109582 Hemostasis 0.0111372377636659 657 44 9 0.204545454545455 0.0136986301369863
REAC REAC:R-HSA-1222556 ROS and RNS production in phagocytes 0.013940717372424 36 70 3 0.0428571428571429 0.0833333333333333
REAC REAC:R-HSA-195258 RHO GTPase Effectors 0.0145576393387003 283 84 8 0.0952380952380952 0.0282685512367491
REAC REAC:R-HSA-1799339 SRP-dependent cotranslational protein targeting to membrane 0.0150830445494859 113 83 5 0.0602409638554217 0.0442477876106195
REAC REAC:R-HSA-2029480 Fcgamma receptor (FCGR) dependent phagocytosis 0.0167893325365256 140 20 3 0.15 0.0214285714285714
REAC REAC:R-HSA-8856828 Clathrin-mediated endocytosis 0.0177010370068912 144 20 3 0.15 0.0208333333333333
REAC REAC:R-HSA-5673001 RAF/MAP kinase cascade 0.0210245365703652 264 12 3 0.25 0.0113636363636364
REAC REAC:R-HSA-5684996 MAPK1/MAPK3 signaling 0.0218830958536583 269 12 3 0.25 0.0111524163568773
REAC REAC:R-HSA-9607240 FLT3 Signaling 0.0231102780420378 278 12 3 0.25 0.0107913669064748
REAC REAC:R-HSA-9716542 Signaling by Rho GTPases, Miro GTPases and RHOBTB3 0.0231102780420378 413 38 6 0.157894736842105 0.0145278450363196
REAC REAC:R-HSA-194315 Signaling by Rho GTPases 0.0231102780420378 413 38 6 0.157894736842105 0.0145278450363196
REAC REAC:R-HSA-216083 Integrin cell surface interactions 0.0247475962628246 84 39 3 0.0769230769230769 0.0357142857142857
REAC REAC:R-HSA-5683057 MAPK family signaling cascades 0.0300954760646298 308 12 3 0.25 0.00974025974025974
REAC REAC:R-HSA-5663202 Diseases of signal transduction by growth factor receptors and second messengers 0.0460336632228176 371 12 3 0.25 0.00808625336927224
TF TF:M00699_1 Factor: ICSBP; motif: RAARTGAAACTG; match class: 1 0.000330517535919802 47 4 3 0.75 0.0638297872340425
TF TF:M06507 Factor: ZFP90; motif: NGGGASTTTAKA 0.00210030365464388 40 9 3 0.333333333333333 0.075
TF TF:M11446 Factor: Elf-1; motif: RANSMGGAAGTR 0.00264599788153014 2915 100 34 0.34 0.011663807890223
TF TF:M00772 Factor: IRF; motif: RRAANTGAAASYGNV 0.00368953818612452 1029 15 7 0.466666666666667 0.00680272108843537
TF TF:M05989 Factor: ZNF275; motif: KGGGMCWTTAGA 0.00368953818612452 36 138 5 0.036231884057971 0.138888888888889
TF TF:M11375_1 Factor: Spi-B; motif: NAWGCGGAAGTN; match class: 1 0.00368953818612452 234 134 10 0.0746268656716418 0.0427350427350427
TF TF:M11777 Factor: RXR-gamma; motif: NRGGTCAYGACCYN 0.00368953818612452 138 17 4 0.235294117647059 0.0289855072463768
TF TF:M11783 Factor: RXR-beta; motif: RRGGTCATGACCYY 0.00393160317282031 144 17 4 0.235294117647059 0.0277777777777778
TF TF:M11387 Factor: elf5; motif: NNNNMGGAAGTN 0.00412635774420739 2598 100 30 0.3 0.0115473441108545
TF TF:M09957 Factor: IRF-2; motif: NAAANNGAAAGTGAAASTRN 0.0047880796981692 272 4 3 0.75 0.0110294117647059
TF TF:M02107 Factor: NF-YC; motif: NRGCCAATYAGMGC 0.00519887680945621 1001 12 6 0.5 0.00599400599400599
TF TF:M03580_1 Factor: Smad2; motif: AGACAN; match class: 1 0.00550772223595866 9070 72 51 0.708333333333333 0.00562293274531422
TF TF:M09956 Factor: IRF-1; motif: NAAANNGAAASTGAAASNRN 0.00550772223595866 317 4 3 0.75 0.00946372239747634
TF TF:M00287 Factor: NF-Y; motif: NNNRRCCAATSRGNNN 0.00550772223595866 1635 12 7 0.583333333333333 0.00428134556574924
TF TF:M11745_1 Factor: COUP-TF1; motif: RAGGTCANTGACCTY; match class: 1 0.00550772223595866 1954 14 8 0.571428571428571 0.00409416581371546
TF TF:M03821_1 Factor: ER-beta; motif: ANNSTGACCYRGNN; match class: 1 0.00676272964204285 1368 4 4 1 0.00292397660818713
TF TF:M08302 Factor: FOXO1A:Net; motif: RWMAACAGGAAGTN 0.00676272964204285 9303 125 82 0.656 0.00881436095883048
TF TF:M02106 Factor: NF-YA; motif: CRGCCAATCAGNRN 0.00676272964204285 1741 12 7 0.583333333333333 0.00402067777139575
TF TF:M04013 Factor: HSFY1; motif: TTCGAANSRTTCGAA 0.0079425992946474 962 9 5 0.555555555555556 0.0051975051975052
TF TF:M08957_1 Factor: NURR1:RXR-ALPHA; motif: NRGGTCRTTGACCYN; match class: 1 0.00822503280962653 3226 13 9 0.692307692307692 0.0027898326100434
TF TF:M11741 Factor: COUP-TF1; motif: RRGGTCRNTGACCYY 0.00963249109434779 3249 25 13 0.52 0.00400123114804555
TF TF:M00051 Factor: NF-kappaB; motif: GGGGATYCCC 0.00963249109434779 6413 9 9 1 0.00140339934508031
TF TF:M07216 Factor: IRF1; motif: NNNYASTTTCACTTTCNNTTT 0.00963249109434779 440 4 3 0.75 0.00681818181818182
TF TF:M11664 Factor: IRF-2; motif: NGAAASYGAAAS 0.00963249109434779 1651 134 26 0.194029850746269 0.015748031496063
TF TF:M00339 Factor: c-Ets-1; motif: RCAGGAAGTGNNTNS 0.00963249109434779 6806 109 58 0.532110091743119 0.00852189244784014
TF TF:M11763_1 Factor: TR2; motif: RRGGTCRYGACCYY; match class: 1 0.00963249109434779 241 17 4 0.235294117647059 0.016597510373444
TF TF:M09903 Factor: elf5; motif: NNNANSAGGAAGTNN 0.00963249109434779 1243 91 17 0.186813186813187 0.0136765888978278
TF TF:M11745 Factor: COUP-TF1; motif: RAGGTCANTGACCTY 0.0099725938388711 5058 14 11 0.785714285714286 0.00217477263740609
TF TF:M00775 Factor: NF-Y; motif: NNNNRRCCAATSR 0.0099725938388711 1428 121 22 0.181818181818182 0.015406162464986
TF TF:M04738 Factor: ER-alpha; motif: AGGTCANMNTGACC 0.011265359323785 4374 135 50 0.37037037037037 0.0114311842706904
TF TF:M11781 Factor: RXR-beta; motif: RRGGTCGTGACCYY 0.0112896754112884 261 17 4 0.235294117647059 0.0153256704980843
TF TF:M11445 Factor: Elf-1; motif: NANCAGGAAGTR 0.0119366398451026 1689 98 21 0.214285714285714 0.0124333925399645
TF TF:M04788 Factor: IRF-1; motif: STTTCACTTTCNNT 0.0128398143552458 536 4 3 0.75 0.00559701492537313
TF TF:M11763 Factor: TR2; motif: RRGGTCRYGACCYY 0.0128398143552458 279 17 4 0.235294117647059 0.014336917562724
TF TF:M08887 Factor: IRF; motif: NNGAAANTGAAANN 0.0128398143552458 1267 5 4 0.8 0.00315706393054459
TF TF:M01719 Factor: OTX2; motif: NRANGGATTARNN 0.0138936559420809 489 129 12 0.0930232558139535 0.0245398773006135
TF TF:M10005 Factor: NF-YA; motif: NYRRCCAATCAGAR 0.0146775043415595 2225 6 5 0.833333333333333 0.00224719101123596
TF TF:M07256 Factor: FXR:RXR; motif: RGGTCANTGACCTN 0.0146775043415595 1642 15 7 0.466666666666667 0.00426309378806334
TF TF:M01203 Factor: SPI1; motif: NNAAWGNGGAASTNNNN 0.0153885586364569 2643 101 28 0.277227722772277 0.0105940219447597
TF TF:M08501 Factor: HOXB2:pitx1; motif: TAATKANGGGATTA 0.0168636497431983 302 7 3 0.428571428571429 0.00993377483443709
TF TF:M11375 Factor: Spi-B; motif: NAWGCGGAAGTN 0.0187204932995225 2608 114 30 0.263157894736842 0.0115030674846626
TF TF:M05946_1 Factor: PRDM16; motif: KGGTCATRACCM; match class: 1 0.0199458673645271 2282 9 6 0.666666666666667 0.00262927256792287
TF TF:M07302 Factor: NF-Y; motif: RGCCAATCRGN 0.0201055281075875 1576 12 6 0.5 0.00380710659898477
TF TF:M10073 Factor: PU.1; motif: NRAAAGAGGAAGTGRNN 0.0201055281075875 2416 101 26 0.257425742574257 0.0107615894039735
TF TF:M03812 Factor: arnt; motif: CACGYA 0.0201055281075875 4330 10 8 0.8 0.00184757505773672
TF TF:M11686 Factor: IRF-4; motif: NYGAAASYGAAACYN 0.0203150354132972 3391 137 41 0.299270072992701 0.0120908286641109
TF TF:M10006 Factor: NF-YC; motif: NNRRCCAATCAGNR 0.0213291305134477 2510 6 5 0.833333333333333 0.00199203187250996
TF TF:M09808 Factor: KLF4; motif: MCACACCCTNN 0.0213291305134477 3799 16 10 0.625 0.00263227165043432
TF TF:M11741_1 Factor: COUP-TF1; motif: RRGGTCRNTGACCYY; match class: 1 0.0236590460232992 1014 12 5 0.416666666666667 0.00493096646942801
TF TF:M04683 Factor: NF-YA; motif: YTCTSATTGGYYRN 0.0236590460232992 1657 12 6 0.5 0.00362100181050091
TF TF:M08302_1 Factor: FOXO1A:Net; motif: RWMAACAGGAAGTN; match class: 1 0.0236590460232992 2779 115 31 0.269565217391304 0.0111550917596258
TF TF:M00341 Factor: GABP; motif: VCCGGAAGNGCR 0.023699074144151 8224 139 79 0.568345323741007 0.00960603112840467
TF TF:M11685 Factor: IRF-8; motif: NCGAAACYGAAACYN 0.023699074144151 1617 134 24 0.17910447761194 0.0148423005565863
TF TF:M09918_1 Factor: Pet-1; motif: GCNGGAAGYG; match class: 1 0.023699074144151 7159 134 69 0.514925373134328 0.00963821762816036
TF TF:M11388 Factor: elf5; motif: AANRAGGAAGTR 0.0237845575257267 660 91 11 0.120879120879121 0.0166666666666667
TF TF:M06202 Factor: ZXDB; motif: NAGGGTG 0.0238898091776644 7463 37 25 0.675675675675676 0.00334985930590915
TF TF:M06203 Factor: ZXDA; motif: NAGGGTG 0.0238898091776644 7463 37 25 0.675675675675676 0.00334985930590915
TF TF:M00971 Factor: Ets; motif: ACTTCCTS 0.0240540024918841 2349 52 16 0.307692307692308 0.00681140911025969
TF TF:M07222 Factor: NFYA; motif: AGNSYKCTGATTGGTNNR 0.0244386582705198 714 114 13 0.114035087719298 0.0182072829131653
TF TF:M11445_1 Factor: Elf-1; motif: NANCAGGAAGTR; match class: 1 0.0248473060569592 83 134 5 0.0373134328358209 0.0602409638554217
TF TF:M08955_1 Factor: FXR:RXR-ALPHA; motif: NRGGTCANRGGKN; match class: 1 0.0253198182766412 3333 107 33 0.308411214953271 0.0099009900990099
TF TF:M00258 Factor: ISGF-3; motif: CAGTTTCWCTTTYCC 0.0254427536061138 823 4 3 0.75 0.00364520048602673
TF TF:M09902 Factor: ESE-1; motif: NNANVAGGAAGTNN 0.0254427536061138 3200 98 30 0.306122448979592 0.009375
TF TF:M04018 Factor: IRF7; motif: NCGAAARYGAAANT 0.0254427536061138 619 5 3 0.6 0.00484652665589661
TF TF:M08239 Factor: ERF:FOXI1; motif: RNAAACMGGAARTN 0.0254427536061138 2246 100 24 0.24 0.0106856634016028
TF TF:M11374 Factor: Spi-B; motif: NAWGRGGAAGTR 0.0254427536061138 2512 101 26 0.257425742574257 0.0103503184713376
TF TF:M11813 Factor: PPARdelta; motif: NRRGGTCATGACCYYT 0.0254427536061138 387 17 4 0.235294117647059 0.0103359173126615
TF TF:M04482 Factor: RARA; motif: ARRGGTCANSNGAGGTCA 0.0254427536061138 3852 121 40 0.330578512396694 0.0103842159916926
TF TF:M00691_1 Factor: ATF-1; motif: CYYTGACGTCA; match class: 1 0.0265411682437895 854 4 3 0.75 0.00351288056206089
TF TF:M11811 Factor: PPARdelta; motif: NRRGGTCGYGACCYYN 0.0270857685155402 403 17 4 0.235294117647059 0.00992555831265509
TF TF:M11670 Factor: IRF-5; motif: NYGAAACCGAAACY 0.0270857685155402 871 4 3 0.75 0.0034443168771527
TF TF:M00655_1 Factor: PEA3; motif: ACWTCCK; match class: 1 0.0270857685155402 2934 107 30 0.280373831775701 0.0102249488752556
TF TF:M01967_1 Factor: Pbx; motif: NKTGATTGACRKSN; match class: 1 0.0274110353580648 889 4 3 0.75 0.00337457817772778
TF TF:M08345 Factor: HOXB2:PEA3; motif: ACCGGAAATGRN 0.0274110353580648 8027 98 57 0.581632653061224 0.00710103401021552
TF TF:M01889 Factor: Smad4; motif: TGTCTGN 0.0274110353580648 5247 50 25 0.5 0.00476462740613684
TF TF:M03834 Factor: N-Myc; motif: GSSCACGYGS 0.0274110353580648 1414 6 4 0.666666666666667 0.00282885431400283
TF TF:M00448 Factor: Zic1; motif: KGGGTGGTC 0.0295285978818782 10948 18 17 0.944444444444444 0.0015527950310559
TF TF:M09773_1 Factor: HIF1A; motif: NNACGTGCNN; match class: 1 0.0297787964315081 683 5 3 0.6 0.00439238653001464
TF TF:M07323 Factor: IRF-4; motif: KRAAMNGAAANYN 0.0299987890985561 938 4 3 0.75 0.00319829424307036
TF TF:M11390 Factor: Erg; motif: NACAGGAARTN 0.0299987890985561 2772 99 27 0.272727272727273 0.00974025974025974
TF TF:M01859_1 Factor: AP-2; motif: NNGCCTK; match class: 1 0.0299987890985561 1898 66 16 0.242424242424242 0.00842992623814542
TF TF:M09916 Factor: Erm; motif: NRRSAGGAARNGRN 0.0299987890985561 6711 103 52 0.504854368932039 0.00774847265683207
TF TF:M00007_1 Factor: Elk-1; motif: NAAACMGGAAGTNCVH; match class: 1 0.0300395657270891 1119 109 16 0.146788990825688 0.0142984807864164
TF TF:M00209 Factor: NF-Y; motif: NCTGATTGGYTASY 0.0300395657270891 3776 12 8 0.666666666666667 0.00211864406779661
TF TF:M00972 Factor: IRF; motif: RAAANTGAAAN 0.0326278241473347 1979 5 4 0.8 0.00202122283981809
TF TF:M01151 Factor: DMRT7; motif: TTGTTACAWTKTKG 0.0327274822423442 1009 14 5 0.357142857142857 0.00495540138751239
TF TF:M08299_1 Factor: FOXO1A:Elk-1; motif: RWMAACAGGAAGTN; match class: 1 0.0329370700235978 1597 110 20 0.181818181818182 0.0125234815278647
TF TF:M11800_1 Factor: NR1B2; motif: RAGGTCRTGACCTY; match class: 1 0.0329370700235978 987 4 3 0.75 0.00303951367781155
TF TF:M09911_1 Factor: c-Ets-1; motif: NNRCMGGAAGTGG; match class: 1 0.0329370700235978 208 35 4 0.114285714285714 0.0192307692307692
TF TF:M01273_1 Factor: SP4; motif: SCCCCGCCCCS; match class: 1 0.0347877492383649 1016 4 3 0.75 0.00295275590551181
TF TF:M10126 Factor: ZNF134; motif: GCCTNNNCTMATCAGKTGAAGG 0.0347877492383649 223 59 5 0.0847457627118644 0.0224215246636771
TF TF:M07379 Factor: c-Ets-2; motif: NNCTTCCTNNN 0.0347877492383649 3487 50 19 0.38 0.00544880986521365
TF TF:M09816 Factor: NFYA; motif: RRCCAATCAGN 0.0347877492383649 1969 12 6 0.5 0.00304723209751143
TF TF:M00195_1 Factor: Oct-1; motif: NNNNATGCAAATNAN; match class: 1 0.035443232524136 550 25 5 0.2 0.00909090909090909
TF TF:M11378 Factor: ESE-1; motif: ACMAGGAAGTANNNNNNNWWAWW 0.0364191035358291 3049 102 29 0.284313725490196 0.00951131518530666
TF TF:M12315 Factor: ZF5; motif: RTGCGCGTGCACGYGN 0.0364191035358291 184 18 3 0.166666666666667 0.016304347826087
TF TF:M08299 Factor: FOXO1A:Elk-1; motif: RWMAACAGGAAGTN 0.0364191035358291 7218 116 60 0.517241379310345 0.00831255195344971
TF TF:M11665 Factor: IRF-2; motif: NGAAASYGAAAS 0.036493088097132 2396 134 30 0.223880597014925 0.0125208681135225
TF TF:M04814 Factor: RelA-p65; motif: AAATCCCCT 0.0374365338607284 4528 5 5 1 0.00110424028268551
TF TF:M01733 Factor: MZF-1; motif: TGGGGAR 0.0376256511853166 11391 44 36 0.818181818181818 0.00316038978140637
TF TF:M11446_1 Factor: Elf-1; motif: RANSMGGAAGTR; match class: 1 0.0382522028919983 309 45 5 0.111111111111111 0.0161812297734628
TF TF:M01165_1 Factor: Elk-1; motif: RACCGGAAGTR; match class: 1 0.0388647695493614 2185 5 4 0.8 0.00183066361556064
TF TF:M00687 Factor: alpha-CP1; motif: CAGCCAATGAG 0.0409750538389053 2326 11 6 0.545454545454545 0.00257953568357696
TF TF:M01878_1 Factor: GATA-3; motif: AGATAA; match class: 1 0.0413993309126345 4168 74 28 0.378378378378378 0.00671785028790787
TF TF:M07251_1 Factor: EHF; motif: BTTCCTGC; match class: 1 0.0415541572869821 1176 99 15 0.151515151515152 0.0127551020408163
TF TF:M03852_1 Factor: SREBP-2; motif: NTCACCYNNNN; match class: 1 0.0418207543271598 2246 5 4 0.8 0.00178094390026714
TF TF:M09726_1 Factor: GATAD2A; motif: CCTKTG; match class: 1 0.041870166621901 9052 74 48 0.648648648648649 0.00530269553689792
TF TF:M11807 Factor: RAR-gamma; motif: RAGGTCATGACCTY 0.0419639473234541 2046 21 8 0.380952380952381 0.00391006842619746
TF TF:M00699 Factor: ICSBP; motif: RAARTGAAACTG 0.0433936650109954 1184 4 3 0.75 0.00253378378378378
TF TF:M08760 Factor: ETV7; motif: NNSCGGAAGTR 0.0437788217818228 2349 139 30 0.215827338129496 0.0127713920817369
TF TF:M00172_1 Factor: AP-1; motif: RSTGACTNMNW; match class: 1 0.0458705109125073 152 96 5 0.0520833333333333 0.0328947368421053
TF TF:M00052_1 Factor: NF-kappaB; motif: GGGRATTTCC; match class: 1 0.0460892151586862 94 90 4 0.0444444444444444 0.0425531914893617
TF TF:M03896 Factor: EGR1; motif: NACGCCCACGCANW 0.0460892151586862 6129 6 6 1 0.000978952520802741
TF TF:M04802 Factor: c-Fos; motif: ACTCACCA 0.0480931649644998 7386 10 9 0.9 0.00121852152721365
TF TF:M10074 Factor: Spi-B; motif: NRAAAGAGGAAGTGARA 0.0496151139389534 1611 91 17 0.186813186813187 0.010552451893234
WP WP:WP4217 Ebola Virus Pathway on Host 1.93386146612573e-09 130 9 7 0.777777777777778 0.0538461538461538
WP WP:WP2328 Allograft Rejection 1.25333834628111e-08 88 9 6 0.666666666666667 0.0681818181818182
WP WP:WP183 Proteasome Degradation 2.80104298583593e-05 64 9 4 0.444444444444444 0.0625
WP WP:WP4534 Mechanoregulation and pathology of YAP/TAZ via Hippo and non-Hippo mechanisms 0.00227832325191384 47 13 3 0.230769230769231 0.0638297872340425
WP WP:WP5027 nsp1 from SARS-CoV-2 inhibits translation initiation in the host cell 0.00239513957788933 17 108 4 0.037037037037037 0.235294117647059
WP WP:WP314 Fas Ligand (FasL) pathway and Stress induction of Heat Shock Proteins (HSP) regulation 0.00352660347142035 44 19 3 0.157894736842105 0.0681818181818182
WP WP:WP2272 Pathogenic Escherichia coli infection 0.00352660347142035 55 71 5 0.0704225352112676 0.0909090909090909
WP WP:WP2118 Arrhythmogenic Right Ventricular Cardiomyopathy 0.00479871123153776 76 13 3 0.230769230769231 0.0394736842105263
WP WP:WP306 Focal Adhesion 0.00645062648787058 201 14 4 0.285714285714286 0.0199004975124378
WP WP:WP3888 VEGFA-VEGFR2 Signaling Pathway 0.0301367453722047 437 140 17 0.121428571428571 0.0389016018306636
WP WP:WP2324 AGE/RAGE pathway 0.0355612645169663 66 74 4 0.0540540540540541 0.0606060606060606
WP WP:WP107 Translation Factors 0.0497350956809029 53 108 4 0.037037037037037 0.0754716981132075
WP WP:WP23 B Cell Receptor Signaling Pathway 0.0497350956809029 98 130 6 0.0461538461538462 0.0612244897959184

pP04 transcription factor target enrichment of top program genes

TF enrichment of pP04
TFs corrosponding to activation of pP04. (Left) pearson correlation of TF expression and gene expression program activatity in Plasma cells, (right) negative log p-value for enrichment of TF binding sites among top uniqueness weighted genes for the gene program. Blue bars indicate significant TFs meeting the following criteria: FDR<0.1, overlap > 2, Corr. R > 0, permutation based p-value < 0.05.