pEpi19 program activity among Epithelial cells

Activation of pEpi19
pEpi19 gene program activation in Epithelial cells. (Top) Activation of program across all epithelial cells. (Bottom) Activation in MMRd (left), MMRp (middle), and normal epithelial cells (right).

Epithelial cell compositional overview

Overview of epithelial cell composition
Overview of epithelial cell composition. A tSNE plot colored by: (left) MMR status of epithelial cells, (middle) specimen, (righ) epithelial cell sub-type.
Gene program activation of pEpi19 by different cell subtypes
pEpi19 gene program activation among cells of different subtypes (Epithelial cells).

pEpi19 top program genes

Top genes of pEpi19 program
Bar plots showing the top genes for each gene program, ranked by (left) unique weights, (right) raw weights.

pEpi19 gene-set enrichment of top program genes (using g-profiler)

GSEA wth gene profiler of pEpi19
pEpi19 gene-set enrichment summary using g-profiler webtool.
Source termID Name Padj Tsize Qsize Overlap Precision Recall
CORUM CORUM:306 Ribosome, cytoplasmic 5.67879168270501e-44 80 29 27 0.931034482758621 0.3375
CORUM CORUM:3055 Nop56p-associated pre-rRNA complex 1.86679573786903e-29 104 28 22 0.785714285714286 0.211538461538462
CORUM CORUM:308 60S ribosomal subunit, cytoplasmic 7.37775809948509e-24 47 29 16 0.551724137931034 0.340425531914894
CORUM CORUM:338 40S ribosomal subunit, cytoplasmic 1.18230355285653e-16 31 28 11 0.392857142857143 0.354838709677419
CORUM CORUM:305 40S ribosomal subunit, cytoplasmic 2.14324695522092e-16 33 28 11 0.392857142857143 0.333333333333333
CORUM CORUM:5380 TRBP containing complex (DICER, RPL7A, EIF6, MOV10 and subunits of the 60S ribosomal particle) 1.68208561145807e-12 25 24 8 0.333333333333333 0.32
GO:BP GO:0006614 SRP-dependent cotranslational protein targeting to membrane 1.9082434017361e-58 96 29 27 0.931034482758621 0.28125
GO:BP GO:0006613 cotranslational protein targeting to membrane 6.37638774905779e-58 102 29 27 0.931034482758621 0.264705882352941
GO:BP GO:0045047 protein targeting to ER 1.0090070897552e-56 113 29 27 0.931034482758621 0.238938053097345
GO:BP GO:0072599 establishment of protein localization to endoplasmic reticulum 2.19473205172514e-56 117 29 27 0.931034482758621 0.230769230769231
GO:BP GO:0000184 nuclear-transcribed mRNA catabolic process, nonsense-mediated decay 8.04299817378131e-56 123 29 27 0.931034482758621 0.219512195121951
GO:BP GO:0070972 protein localization to endoplasmic reticulum 1.15057885181805e-53 146 29 27 0.931034482758621 0.184931506849315
GO:BP GO:0019083 viral transcription 5.48576070366253e-51 181 29 27 0.931034482758621 0.149171270718232
GO:BP GO:0019080 viral gene expression 7.52025182693135e-50 199 29 27 0.931034482758621 0.135678391959799
GO:BP GO:0006413 translational initiation 8.92518238612705e-50 201 29 27 0.931034482758621 0.134328358208955
GO:BP GO:0006612 protein targeting to membrane 1.23217668567877e-49 204 29 27 0.931034482758621 0.132352941176471
GO:BP GO:0000956 nuclear-transcribed mRNA catabolic process 4.44789064818889e-49 214 29 27 0.931034482758621 0.126168224299065
GO:BP GO:0090150 establishment of protein localization to membrane 5.05933057334963e-43 351 29 27 0.931034482758621 0.0769230769230769
GO:BP GO:0006402 mRNA catabolic process 5.76300699916213e-42 384 29 27 0.931034482758621 0.0703125
GO:BP GO:0006401 RNA catabolic process 8.46616986570104e-41 424 29 27 0.931034482758621 0.0636792452830189
GO:BP GO:0006605 protein targeting 2.35687141352397e-40 441 29 27 0.931034482758621 0.0612244897959184
GO:BP GO:0034655 nucleobase-containing compound catabolic process 2.31678757831883e-37 567 29 27 0.931034482758621 0.0476190476190476
GO:BP GO:0072594 establishment of protein localization to organelle 4.92295377592729e-37 584 29 27 0.931034482758621 0.0462328767123288
GO:BP GO:0046700 heterocycle catabolic process 1.07286870078701e-36 602 29 27 0.931034482758621 0.0448504983388704
GO:BP GO:0044270 cellular nitrogen compound catabolic process 1.33550201516176e-36 608 29 27 0.931034482758621 0.0444078947368421
GO:BP GO:0006412 translation 2.03181413485015e-36 764 29 28 0.96551724137931 0.0366492146596859
GO:BP GO:0019439 aromatic compound catabolic process 2.3629697446148e-36 623 29 27 0.931034482758621 0.043338683788122
GO:BP GO:0043043 peptide biosynthetic process 4.78686584862517e-36 790 29 28 0.96551724137931 0.0354430379746835
GO:BP GO:1901361 organic cyclic compound catabolic process 7.22677502168178e-36 651 29 27 0.931034482758621 0.0414746543778802
GO:BP GO:0072657 protein localization to membrane 1.24266558794019e-35 665 29 27 0.931034482758621 0.0406015037593985
GO:BP GO:0043604 amide biosynthetic process 4.6082117653663e-34 932 29 28 0.96551724137931 0.0300429184549356
GO:BP GO:0006518 peptide metabolic process 8.84532550500029e-34 955 29 28 0.96551724137931 0.0293193717277487
GO:BP GO:0016071 mRNA metabolic process 1.96735803601448e-32 874 29 27 0.931034482758621 0.0308924485125858
GO:BP GO:0016032 viral process 1.46619786383324e-31 942 29 27 0.931034482758621 0.0286624203821656
GO:BP GO:0044403 biological process involved in symbiotic interaction 7.41544462503474e-31 1001 29 27 0.931034482758621 0.026973026973027
GO:BP GO:0033365 protein localization to organelle 1.10412061753311e-30 1017 29 27 0.931034482758621 0.0265486725663717
GO:BP GO:0043603 cellular amide metabolic process 1.22775366185567e-30 1241 29 28 0.96551724137931 0.0225624496373892
GO:BP GO:0006886 intracellular protein transport 6.77670401895706e-29 1186 29 27 0.931034482758621 0.0227655986509275
GO:BP GO:0009057 macromolecule catabolic process 1.3175101354095e-28 1468 29 28 0.96551724137931 0.0190735694822888
GO:BP GO:0044265 cellular macromolecule catabolic process 1.75353882132456e-28 1231 29 27 0.931034482758621 0.0219333874898457
GO:BP GO:0010629 negative regulation of gene expression 1.73846586212475e-26 1460 29 27 0.931034482758621 0.0184931506849315
GO:BP GO:1901566 organonitrogen compound biosynthetic process 8.46971147522918e-26 1853 29 28 0.96551724137931 0.0151106314085267
GO:BP GO:0046907 intracellular transport 2.8622609767698e-24 1767 29 27 0.931034482758621 0.0152801358234295
GO:BP GO:0044419 biological process involved in interspecies interaction between organisms 1.98366033138643e-23 2255 29 28 0.96551724137931 0.0124168514412417
GO:BP GO:1901575 organic substance catabolic process 2.24283984545382e-23 2267 29 28 0.96551724137931 0.0123511248345831
GO:BP GO:0015031 protein transport 2.82126199491238e-23 1929 29 27 0.931034482758621 0.0139968895800933
GO:BP GO:0015833 peptide transport 4.91836987227328e-23 1971 29 27 0.931034482758621 0.0136986301369863
GO:BP GO:0044248 cellular catabolic process 5.50445522538056e-23 2347 29 28 0.96551724137931 0.011930123561994
GO:BP GO:0042886 amide transport 7.63686780569e-23 2007 29 27 0.931034482758621 0.0134529147982063
GO:BP GO:0034613 cellular protein localization 8.1971247434489e-23 2014 29 27 0.931034482758621 0.0134061569016882
GO:BP GO:0070727 cellular macromolecule localization 9.15881253425686e-23 2024 29 27 0.931034482758621 0.0133399209486166
GO:BP GO:0045184 establishment of protein localization 1.0367878598223e-22 2035 29 27 0.931034482758621 0.0132678132678133
GO:BP GO:0071705 nitrogen compound transport 3.5295372142487e-21 2322 29 27 0.931034482758621 0.0116279069767442
GO:BP GO:0009056 catabolic process 3.82536290823988e-21 2744 29 28 0.96551724137931 0.0102040816326531
GO:BP GO:0051649 establishment of localization in cell 7.50443201749134e-21 2813 29 28 0.96551724137931 0.00995378599360114
GO:BP GO:0002181 cytoplasmic translation 1.42025117840223e-19 103 27 12 0.444444444444444 0.116504854368932
GO:BP GO:0071702 organic substance transport 3.55506243934332e-19 2766 29 27 0.931034482758621 0.00976138828633406
GO:BP GO:0008104 protein localization 3.62428496793133e-19 2770 29 27 0.931034482758621 0.00974729241877256
GO:BP GO:0006820 anion transport 1.09643999045565e-18 2889 29 27 0.931034482758621 0.00934579439252336
GO:BP GO:0051641 cellular localization 4.20410331010738e-18 3541 29 28 0.96551724137931 0.00790737079920926
GO:BP GO:0006811 ion transport 1.04486710731328e-17 3661 29 28 0.96551724137931 0.00764818355640535
GO:BP GO:0033036 macromolecule localization 1.85344370552623e-17 3218 29 27 0.931034482758621 0.00839030453697949
GO:BP GO:0010605 negative regulation of macromolecule metabolic process 2.20220430811999e-17 3241 29 27 0.931034482758621 0.00833076211045974
GO:BP GO:0009892 negative regulation of metabolic process 1.43244686125799e-16 3479 29 27 0.931034482758621 0.00776085081920092
GO:BP GO:0006810 transport 2.59906625859749e-15 5224 29 29 1 0.00555130168453292
GO:BP GO:0051234 establishment of localization 5.75842335123024e-15 5372 29 29 1 0.00539836187639613
GO:BP GO:0044271 cellular nitrogen compound biosynthetic process 5.98481540308347e-14 5017 29 28 0.96551724137931 0.00558102451664341
GO:BP GO:0034645 cellular macromolecule biosynthetic process 7.10012388991476e-14 5051 29 28 0.96551724137931 0.00554345674123936
GO:BP GO:0009059 macromolecule biosynthetic process 9.85037767367626e-14 5114 29 28 0.96551724137931 0.00547516621040282
GO:BP GO:0044267 cellular protein metabolic process 1.79501883590618e-13 5229 29 28 0.96551724137931 0.00535475234270415
GO:BP GO:0016070 RNA metabolic process 3.95917545637533e-13 4710 29 27 0.931034482758621 0.00573248407643312
GO:BP GO:0048519 negative regulation of biological process 2.4893396099587e-12 5757 29 28 0.96551724137931 0.00486364425916276
GO:BP GO:0019538 protein metabolic process 3.12859059823395e-12 5808 29 28 0.96551724137931 0.00482093663911846
GO:BP GO:0010468 regulation of gene expression 5.03558532843895e-12 5196 29 27 0.931034482758621 0.00519630484988453
GO:BP GO:0090304 nucleic acid metabolic process 5.77387927815092e-12 5226 29 27 0.931034482758621 0.00516647531572905
GO:BP GO:0051179 localization 7.16401851527276e-12 6901 29 29 1 0.0042022895232575
GO:BP GO:0044249 cellular biosynthetic process 1.45769700738141e-11 6154 29 28 0.96551724137931 0.00454988625284368
GO:BP GO:0010467 gene expression 1.60745611756857e-11 6179 29 28 0.96551724137931 0.0045314775853698
GO:BP GO:1901576 organic substance biosynthetic process 2.15324924779755e-11 6248 29 28 0.96551724137931 0.00448143405889885
GO:BP GO:0009058 biosynthetic process 3.17770887238492e-11 6340 29 28 0.96551724137931 0.00441640378548896
GO:BP GO:0006139 nucleobase-containing compound metabolic process 6.40123702571316e-11 5746 29 27 0.931034482758621 0.00469892098851375
GO:BP GO:0034641 cellular nitrogen compound metabolic process 8.01523058073161e-11 6563 29 28 0.96551724137931 0.00426634161206765
GO:BP GO:0060255 regulation of macromolecule metabolic process 9.35090385685615e-11 6603 29 28 0.96551724137931 0.00424049674390429
GO:BP GO:0046483 heterocycle metabolic process 1.25153474141916e-10 5904 29 27 0.931034482758621 0.00457317073170732
GO:BP GO:0006725 cellular aromatic compound metabolic process 1.55400199510506e-10 5956 29 27 0.931034482758621 0.00453324378777703
GO:BP GO:1901564 organonitrogen compound metabolic process 1.95579609273804e-10 6792 29 28 0.96551724137931 0.00412249705535925
GO:BP GO:1901360 organic cyclic compound metabolic process 4.34077012766844e-10 6201 29 27 0.931034482758621 0.00435413642960813
GO:BP GO:0019222 regulation of metabolic process 7.76117981245779e-10 7148 29 28 0.96551724137931 0.00391717963066592
GO:BP GO:0044260 cellular macromolecule metabolic process 6.12525796921007e-08 8390 29 28 0.96551724137931 0.0033373063170441
GO:BP GO:0022613 ribonucleoprotein complex biogenesis 1.23901955389376e-07 446 28 9 0.321428571428571 0.0201793721973094
GO:BP GO:0042254 ribosome biogenesis 1.25930929106478e-07 307 28 8 0.285714285714286 0.0260586319218241
GO:BP GO:0006364 rRNA processing 3.3077802830738e-07 224 28 7 0.25 0.03125
GO:BP GO:0016072 rRNA metabolic process 4.41187975668029e-07 234 28 7 0.25 0.0299145299145299
GO:BP GO:0043170 macromolecule metabolic process 3.84864385098535e-06 9796 29 28 0.96551724137931 0.00285830951408738
GO:BP GO:0006807 nitrogen compound metabolic process 8.1678745935368e-06 10078 29 28 0.96551724137931 0.0027783290335384
GO:BP GO:0034470 ncRNA processing 1.51558846990418e-05 397 28 7 0.25 0.017632241813602
GO:BP GO:0044238 primary metabolic process 2.97085650334939e-05 10584 29 28 0.96551724137931 0.00264550264550265
GO:BP GO:0044237 cellular metabolic process 6.00320221070545e-05 10871 29 28 0.96551724137931 0.0025756600128783
GO:BP GO:0034660 ncRNA metabolic process 6.11406006257887e-05 493 28 7 0.25 0.0141987829614604
GO:BP GO:0050789 regulation of biological process 6.32519142712018e-05 12091 29 29 1 0.00239847820693077
GO:BP GO:0071704 organic substance metabolic process 0.000172927236733088 11326 29 28 0.96551724137931 0.00247218788627936
GO:BP GO:0065007 biological regulation 0.000330587263571518 12809 29 29 1 0.00226403310172535
GO:BP GO:0006414 translational elongation 0.000408637727645758 141 10 3 0.3 0.0212765957446809
GO:BP GO:0008152 metabolic process 0.000526056581081547 11827 29 28 0.96551724137931 0.00236746427665511
GO:BP GO:0042255 ribosome assembly 0.000871067508486814 64 27 3 0.111111111111111 0.046875
GO:BP GO:0042274 ribosomal small subunit biogenesis 0.00105075353417764 74 25 3 0.12 0.0405405405405405
GO:BP GO:0042273 ribosomal large subunit biogenesis 0.00131531339570306 74 27 3 0.111111111111111 0.0405405405405405
GO:BP GO:0022618 ribonucleoprotein complex assembly 0.00142882351119383 197 27 4 0.148148148148148 0.0203045685279188
GO:BP GO:0071826 ribonucleoprotein complex subunit organization 0.00160165628148851 204 27 4 0.148148148148148 0.0196078431372549
GO:BP GO:0006396 RNA processing 0.00370599094141479 964 28 7 0.25 0.00726141078838174
GO:BP GO:2001242 regulation of intrinsic apoptotic signaling pathway 0.00544079972003035 167 20 3 0.15 0.0179640718562874
GO:BP GO:0006417 regulation of translation 0.0148710196489239 462 23 4 0.173913043478261 0.00865800865800866
GO:BP GO:0044085 cellular component biogenesis 0.0161961445820703 3257 29 12 0.413793103448276 0.00368437212158428
GO:BP GO:0097193 intrinsic apoptotic signaling pathway 0.0218491151029514 294 20 3 0.15 0.0102040816326531
GO:BP GO:0031396 regulation of protein ubiquitination 0.0225558160755652 211 28 3 0.107142857142857 0.014218009478673
GO:BP GO:0034248 regulation of cellular amide metabolic process 0.0231678741923201 535 23 4 0.173913043478261 0.00747663551401869
GO:BP GO:0051338 regulation of transferase activity 0.0276874834177156 1035 29 6 0.206896551724138 0.00579710144927536
GO:BP GO:1903320 regulation of protein modification by small protein conjugation or removal 0.0308914559028841 243 28 3 0.107142857142857 0.0123456790123457
GO:BP GO:2001233 regulation of apoptotic signaling pathway 0.0353030309391703 363 20 3 0.15 0.00826446280991736
GO:BP GO:0034622 cellular protein-containing complex assembly 0.0359931947894349 1107 29 6 0.206896551724138 0.00542005420054201
GO:BP GO:0070925 organelle assembly 0.0452879826868863 895 27 5 0.185185185185185 0.00558659217877095
GO:CC GO:0022626 cytosolic ribosome 4.98427028497769e-58 109 29 27 0.931034482758621 0.247706422018349
GO:CC GO:0044391 ribosomal subunit 3.9298179844049e-51 190 29 27 0.931034482758621 0.142105263157895
GO:CC GO:0005840 ribosome 3.92174760080533e-48 245 29 27 0.931034482758621 0.110204081632653
GO:CC GO:1990904 ribonucleoprotein complex 9.49192430751469e-36 688 29 27 0.931034482758621 0.0392441860465116
GO:CC GO:0022625 cytosolic large ribosomal subunit 7.3385183478145e-33 57 29 16 0.551724137931034 0.280701754385965
GO:CC GO:0015934 large ribosomal subunit 2.36417185619836e-27 118 29 16 0.551724137931034 0.135593220338983
GO:CC GO:0022627 cytosolic small ribosomal subunit 1.06444396502287e-23 47 29 12 0.413793103448276 0.25531914893617
GO:CC GO:0015935 small ribosomal subunit 4.549609910574e-21 75 29 12 0.413793103448276 0.16
GO:CC GO:0005829 cytosol 1.20052627314436e-15 5303 29 29 1 0.00546860267772959
GO:CC GO:0043232 intracellular non-membrane-bounded organelle 1.24223106113008e-15 5338 29 29 1 0.00543274634694642
GO:CC GO:0043228 non-membrane-bounded organelle 1.24223106113008e-15 5346 29 29 1 0.00542461653572765
GO:CC GO:0032991 protein-containing complex 2.39226365893989e-13 5548 29 28 0.96551724137931 0.00504686373467916
GO:CC GO:0042788 polysomal ribosome 2.60763033902142e-13 34 27 7 0.259259259259259 0.205882352941176
GO:CC GO:0005844 polysome 5.50488909398709e-13 72 27 8 0.296296296296296 0.111111111111111
GO:CC GO:0005925 focal adhesion 2.23374978844159e-12 420 28 12 0.428571428571429 0.0285714285714286
GO:CC GO:0030055 cell-substrate junction 2.54609079821289e-12 427 28 12 0.428571428571429 0.0281030444964871
GO:CC GO:0070161 anchoring junction 5.91264385469556e-09 836 28 12 0.428571428571429 0.0143540669856459
GO:CC GO:0030054 cell junction 5.85500976659725e-08 2105 29 16 0.551724137931034 0.00760095011876485
GO:CC GO:0005730 nucleolus 1.28568193591483e-07 955 26 11 0.423076923076923 0.0115183246073298
GO:CC GO:0070062 extracellular exosome 7.68360123974044e-07 2176 29 15 0.517241379310345 0.00689338235294118
GO:CC GO:1903561 extracellular vesicle 1.17813942261941e-06 2261 29 15 0.517241379310345 0.00663423264042459
GO:CC GO:0043230 extracellular organelle 1.17813942261941e-06 2263 29 15 0.517241379310345 0.0066283694211224
GO:CC GO:0005737 cytoplasm 7.61643830342554e-06 11911 29 29 1 0.00243472420451683
GO:CC GO:0043229 intracellular organelle 2.90253521187137e-05 12491 29 29 1 0.00232167160355456
GO:CC GO:0031981 nuclear lumen 5.04000111313231e-05 4444 29 18 0.620689655172414 0.00405040504050405
GO:CC GO:0005615 extracellular space 7.13005823620906e-05 3594 29 16 0.551724137931034 0.00445186421814135
GO:CC GO:0014069 postsynaptic density 0.000307893096216498 334 25 5 0.2 0.0149700598802395
GO:CC GO:0032279 asymmetric synapse 0.000322992796931549 340 25 5 0.2 0.0147058823529412
GO:CC GO:0099572 postsynaptic specialization 0.0003978321692201 358 25 5 0.2 0.0139664804469274
GO:CC GO:0098984 neuron to neuron synapse 0.000426734211929251 366 25 5 0.2 0.0136612021857923
GO:CC GO:0045202 synapse 0.000506493805433572 1349 29 9 0.310344827586207 0.00667160859896219
GO:CC GO:0043226 organelle 0.000606678328205098 14008 29 29 1 0.00207024557395774
GO:CC GO:0070013 intracellular organelle lumen 0.000647484851322744 5402 29 18 0.620689655172414 0.00333209922251018
GO:CC GO:0031974 membrane-enclosed lumen 0.000924079811439461 5565 29 18 0.620689655172414 0.00323450134770889
GO:CC GO:0043233 organelle lumen 0.000924079811439461 5565 29 18 0.620689655172414 0.00323450134770889
GO:CC GO:0031982 vesicle 0.00107355753717238 4055 29 15 0.517241379310345 0.00369913686806412
GO:CC GO:0005576 extracellular region 0.00107355753717238 4567 29 16 0.551724137931034 0.00350339391285308
GO:CC GO:0005783 endoplasmic reticulum 0.00157191642534346 1982 29 10 0.344827586206897 0.00504540867810293
GO:CC GO:0005622 intracellular anatomical structure 0.00240923662915191 14790 29 29 1 0.00196078431372549
GO:CC GO:0098794 postsynapse 0.0039263147773253 639 25 5 0.2 0.00782472613458529
GO:CC GO:0005634 nucleus 0.00453143946635729 7592 29 20 0.689655172413793 0.00263435194942044
GO:CC GO:0016020 membrane 0.00604898050747387 9838 29 23 0.793103448275862 0.00233787355153486
GO:CC GO:0005654 nucleoplasm 0.0117324805431353 4102 29 13 0.448275862068966 0.00316918576304242
GO:CC GO:0012505 endomembrane system 0.0118672961598717 4640 18 10 0.555555555555556 0.0021551724137931
GO:CC GO:0043227 membrane-bounded organelle 0.0158125418762678 12858 29 26 0.896551724137931 0.00202208741639446
GO:CC GO:0043231 intracellular membrane-bounded organelle 0.0171160438027092 11296 29 24 0.827586206896552 0.00212464589235127
GO:MF GO:0003735 structural constituent of ribosome 4.66038646489337e-52 171 29 27 0.931034482758621 0.157894736842105
GO:MF GO:0005198 structural molecule activity 3.60277727734796e-35 698 29 27 0.931034482758621 0.0386819484240688
GO:MF GO:0003723 RNA binding 2.65935919306011e-22 1943 28 26 0.928571428571429 0.013381369016984
GO:MF GO:0003676 nucleic acid binding 1.32371012473958e-13 4276 28 26 0.928571428571429 0.00608044901777362
GO:MF GO:0019843 rRNA binding 4.76134695690937e-11 63 26 7 0.269230769230769 0.111111111111111
GO:MF GO:1901363 heterocyclic compound binding 1.20825882763136e-09 6228 28 26 0.928571428571429 0.00417469492614001
GO:MF GO:0097159 organic cyclic compound binding 1.43238378571077e-09 6309 28 26 0.928571428571429 0.00412109684577588
GO:MF GO:0045182 translation regulator activity 0.00105725195350954 155 11 3 0.272727272727273 0.0193548387096774
GO:MF GO:0045296 cadherin binding 0.0013247838037351 333 28 5 0.178571428571429 0.015015015015015
GO:MF GO:0050839 cell adhesion molecule binding 0.00955876641591475 546 28 5 0.178571428571429 0.00915750915750916
GO:MF GO:0003729 mRNA binding 0.00955876641591475 552 28 5 0.178571428571429 0.00905797101449275
HP HP:0012133 Erythroid hypoplasia 0.00135266407600285 25 20 4 0.2 0.16
HP HP:0012131 Abnormal number of erythroid precursors 0.00380232956329925 38 20 4 0.2 0.105263157894737
HP HP:0001972 Macrocytic anemia 0.0062661741731643 60 20 4 0.2 0.0666666666666667
HP HP:0005532 Macrocytic dyserythropoietic anemia 0.0062661741731643 23 20 3 0.15 0.130434782608696
HP HP:0001894 Thrombocytosis 0.0062661741731643 50 20 4 0.2 0.08
HP HP:0030270 Elevated red cell adenosine deaminase level 0.0062661741731643 22 20 3 0.15 0.136363636363636
HP HP:0020118 Radial artery aplasia 0.0062661741731643 22 20 3 0.15 0.136363636363636
HP HP:0031640 Abnormal radial artery morphology 0.0062661741731643 22 20 3 0.15 0.136363636363636
HP HP:0004808 Acute myeloid leukemia 0.00663357055422292 67 8 3 0.375 0.0447761194029851
HP HP:0012410 Pure red cell aplasia 0.00663357055422292 25 20 3 0.15 0.12
HP HP:0006758 Malignant genitourinary tract tumor 0.00663357055422292 26 20 3 0.15 0.115384615384615
HP HP:0040276 Adenocarcinoma of the colon 0.00682143307550484 27 20 3 0.15 0.111111111111111
HP HP:0011904 Persistence of hemoglobin F 0.00704093122700876 30 20 3 0.15 0.1
HP HP:0040275 Adenocarcinoma of the large intestine 0.00704093122700876 30 20 3 0.15 0.1
HP HP:0030272 Abnormal erythrocyte enzyme level 0.00704093122700876 29 20 3 0.15 0.103448275862069
HP HP:0001227 Abnormality of the thenar eminence 0.00704093122700876 29 20 3 0.15 0.103448275862069
HP HP:0001895 Normochromic anemia 0.00731592459626438 31 20 3 0.15 0.0967741935483871
HP HP:0001896 Reticulocytopenia 0.00790019957766958 33 20 3 0.15 0.0909090909090909
HP HP:0002669 Osteosarcoma 0.00790019957766958 33 20 3 0.15 0.0909090909090909
HP HP:0040273 Adenocarcinoma of the intestines 0.00852582875692888 35 20 3 0.15 0.0857142857142857
HP HP:0002488 Acute leukemia 0.00950669927780261 103 8 3 0.375 0.029126213592233
HP HP:0002863 Myelodysplasia 0.00950669927780261 101 8 3 0.375 0.0297029702970297
HP HP:0005518 Increased mean corpuscular volume 0.00950669927780261 39 20 3 0.15 0.0769230769230769
HP HP:0009944 Partial duplication of thumb phalanx 0.00950669927780261 37 20 3 0.15 0.0810810810810811
HP HP:0009999 Partial duplication of the phalanx of hand 0.00950669927780261 39 20 3 0.15 0.0769230769230769
HP HP:0001790 Nonimmune hydrops fetalis 0.0106176181463861 41 20 3 0.15 0.0731707317073171
HP HP:0009777 Absent thumb 0.0126121417682248 44 20 3 0.15 0.0681818181818182
HP HP:0025065 Abnormal mean corpuscular volume 0.0167008108064357 49 20 3 0.15 0.0612244897959184
HP HP:0000912 Sprengel anomaly 0.0170104742332192 51 20 3 0.15 0.0588235294117647
HP HP:0009942 Duplication of thumb phalanx 0.0183572697956278 53 20 3 0.15 0.0566037735849057
HP HP:0001909 Leukemia 0.0183572697956278 143 8 3 0.375 0.020979020979021
HP HP:0011902 Abnormal hemoglobin 0.0183666487235571 54 20 3 0.15 0.0555555555555556
HP HP:0010972 Anemia of inadequate production 0.0241967022158532 165 8 3 0.375 0.0181818181818182
HP HP:0001087 Developmental glaucoma 0.0262378741119212 64 20 3 0.15 0.046875
HP HP:0009380 Aplasia of the fingers 0.0266548284928931 66 20 3 0.15 0.0454545454545455
HP HP:0006749 Malignant gastrointestinal tract tumors 0.0266548284928931 66 20 3 0.15 0.0454545454545455
HP HP:0002672 Gastrointestinal carcinoma 0.0266548284928931 66 20 3 0.15 0.0454545454545455
HP HP:0001199 Triphalangeal thumb 0.0271926716472017 67 20 3 0.15 0.0447761194029851
HP HP:0001882 Leukopenia 0.0401770053690394 218 8 3 0.375 0.0137614678899083
HP HP:0004377 Hematological neoplasm 0.0480518558398665 240 8 3 0.375 0.0125
HPA HPA:0350473 pancreas; exocrine glandular cells[High] 6.23775592785001e-06 1879 27 18 0.666666666666667 0.00957956359765833
HPA HPA:0250132 hippocampus; neuronal cells[≥Medium] 0.000567199150869443 4126 25 21 0.84 0.00508967523024721
HPA HPA:0470682 skin 2; epidermal cells[≥Medium] 0.000656394523981701 4735 25 22 0.88 0.00464625131995776
HPA HPA:0350472 pancreas; exocrine glandular cells[≥Medium] 0.00264713234712286 5157 25 22 0.88 0.0042660461508629
HPA HPA:0420052 salivary gland; glandular cells[≥Medium] 0.00296538591253612 4742 25 21 0.84 0.00442851117671868
HPA HPA:0190223 esophagus; squamous epithelial cells[High] 0.005486662920693 1596 29 13 0.448275862068966 0.0081453634085213
HPA HPA:0160052 endometrium 1; glandular cells[≥Medium] 0.00578540607260917 5014 25 21 0.84 0.00418827283605903
HPA HPA:0090162 cerebellum; Purkinje cells[≥Medium] 0.00582860920395129 4047 9 9 1 0.0022238695329874
HPA HPA:0530721 spleen; cells in white pulp[≥Low] 0.00655593687776797 4249 25 19 0.76 0.00447164038597317
HPA HPA:0380511 placenta; decidual cells[≥Low] 0.00655593687776797 4716 25 20 0.8 0.00424088210347752
HPA HPA:0330222 oral mucosa; squamous epithelial cells[≥Medium] 0.00655593687776797 4254 25 19 0.76 0.00446638457921956
HPA HPA:0540053 stomach 1; glandular cells[High] 0.00655593687776797 2365 28 15 0.535714285714286 0.00634249471458774
HPA HPA:0570752 testis; elongated or late spermatids[≥Medium] 0.0072199770000642 1420 4 4 1 0.0028169014084507
HPA HPA:0110222 cervix, uterine; squamous epithelial cells[≥Medium] 0.00756297039658582 3617 29 19 0.655172413793103 0.00525297207630633
HPA HPA:0550053 stomach 2; glandular cells[High] 0.00756297039658582 2350 29 15 0.517241379310345 0.00638297872340425
HPA HPA:0620000 vagina 0.00756297039658582 5868 25 22 0.88 0.00374914792092706
HPA HPA:0250133 hippocampus; neuronal cells[High] 0.00756297039658582 1210 27 10 0.37037037037037 0.00826446280991736
HPA HPA:0620221 vagina; squamous epithelial cells[≥Low] 0.00756297039658582 5868 25 22 0.88 0.00374914792092706
HPA HPA:0310431 lymph node; germinal center cells[≥Low] 0.00840652162657928 4935 25 20 0.8 0.00405268490374873
HPA HPA:0060102 bronchus; respiratory epithelial cells[≥Medium] 0.0092255979405233 5184 29 23 0.793103448275862 0.00443672839506173
HPA HPA:0090163 cerebellum; Purkinje cells[High] 0.00936822678547865 1527 27 11 0.407407407407407 0.00720366732154551
HPA HPA:0170053 endometrium 2; glandular cells[High] 0.00936822678547865 1282 27 10 0.37037037037037 0.0078003120124805
HPA HPA:0210052 fallopian tube; glandular cells[≥Medium] 0.00936822678547865 5023 25 20 0.8 0.00398168425243878
HPA HPA:0250131 hippocampus; neuronal cells[≥Low] 0.00965346155395466 6101 25 22 0.88 0.00360596623504344
HPA HPA:0570751 testis; elongated or late spermatids[≥Low] 0.00965346155395466 1798 4 4 1 0.00222469410456062
HPA HPA:0210051 fallopian tube; glandular cells[≥Low] 0.00965346155395466 6089 25 22 0.88 0.00361307275414682
HPA HPA:0110223 cervix, uterine; squamous epithelial cells[High] 0.00965346155395466 986 29 9 0.310344827586207 0.00912778904665314
HPA HPA:0030052 appendix; glandular cells[≥Medium] 0.0113629139958842 5767 29 24 0.827586206896552 0.00416160915554014
HPA HPA:0610832 urinary bladder; urothelial cells[≥Medium] 0.0129849989869675 5819 29 24 0.827586206896552 0.00412442000343702
HPA HPA:0190222 esophagus; squamous epithelial cells[≥Medium] 0.0143005792638345 4937 15 13 0.866666666666667 0.00263317804334616
HPA HPA:0600223 tonsil; squamous epithelial cells[High] 0.0151053937782839 1442 27 10 0.37037037037037 0.00693481276005548
HPA HPA:0290402 liver; hepatocytes[≥Medium] 0.0151053937782839 3640 29 18 0.620689655172414 0.00494505494505494
HPA HPA:0600222 tonsil; squamous epithelial cells[≥Medium] 0.0151053937782839 4851 25 19 0.76 0.00391671820243249
HPA HPA:0600432 tonsil; germinal center cells[≥Medium] 0.0151053937782839 3988 25 17 0.68 0.00426278836509529
HPA HPA:0110221 cervix, uterine; squamous epithelial cells[≥Low] 0.0151053937782839 5325 25 20 0.8 0.00375586854460094
HPA HPA:0150053 duodenum; glandular cells[High] 0.0151053937782839 2767 28 15 0.535714285714286 0.00542103361040838
HPA HPA:0310000 lymph node 0.0153073627524393 6374 25 22 0.88 0.00345152180734233
HPA HPA:0100132 cerebral cortex; neuronal cells[≥Medium] 0.0153073627524393 4883 25 19 0.76 0.00389105058365759
HPA HPA:0330223 oral mucosa; squamous epithelial cells[High] 0.0153331991546049 1112 29 9 0.310344827586207 0.00809352517985612
HPA HPA:0480052 small intestine; glandular cells[≥Medium] 0.0168813436286757 6461 29 25 0.862068965517241 0.00386937006655317
HPA HPA:0090161 cerebellum; Purkinje cells[≥Low] 0.0168813436286757 5460 9 9 1 0.00164835164835165
HPA HPA:0150052 duodenum; glandular cells[≥Medium] 0.0174460267161323 6480 29 25 0.862068965517241 0.00385802469135802
HPA HPA:0420053 salivary gland; glandular cells[High] 0.0196629938909873 1418 29 10 0.344827586206897 0.00705218617771509
HPA HPA:0530722 spleen; cells in white pulp[≥Medium] 0.0196629938909873 2645 25 13 0.52 0.00491493383742911
HPA HPA:0380521 placenta; trophoblastic cells[≥Low] 0.0196629938909873 6388 16 15 0.9375 0.00234815278647464
HPA HPA:0100131 cerebral cortex; neuronal cells[≥Low] 0.0206088114316404 6566 29 25 0.862068965517241 0.00380749314651234
HPA HPA:0110051 cervix, uterine; glandular cells[≥Low] 0.021029166292729 5579 16 14 0.875 0.00250941028858218
HPA HPA:0550052 stomach 2; glandular cells[≥Medium] 0.021029166292729 6134 29 24 0.827586206896552 0.0039126181936746
HPA HPA:0380512 placenta; decidual cells[≥Medium] 0.0210815029964964 3463 27 16 0.592592592592593 0.00462027144094716
HPA HPA:0430052 seminal vesicle; glandular cells[≥Medium] 0.0210815029964964 5096 25 19 0.76 0.00372841444270016
HPA HPA:0470000 skin 2 0.0210815029964964 6608 25 22 0.88 0.00332929782082324
HPA HPA:0470681 skin 2; epidermal cells[≥Low] 0.0210815029964964 6608 25 22 0.88 0.00332929782082324
HPA HPA:0170252 endometrium 2; cells in endometrial stroma[≥Medium] 0.0210815029964964 1722 29 11 0.379310344827586 0.00638792102206736
HPA HPA:0330221 oral mucosa; squamous epithelial cells[≥Low] 0.0215521595879664 6102 25 21 0.84 0.00344149459193707
HPA HPA:0330000 oral mucosa 0.0215521595879664 6102 25 21 0.84 0.00344149459193707
HPA HPA:0540052 stomach 1; glandular cells[≥Medium] 0.0216073586135335 6201 29 24 0.827586206896552 0.003870343492985
HPA HPA:0160051 endometrium 1; glandular cells[≥Low] 0.0220896683958735 6663 29 25 0.862068965517241 0.00375206363499925
HPA HPA:0060101 bronchus; respiratory epithelial cells[≥Low] 0.0224237584682424 6226 29 24 0.827586206896552 0.00385480244137488
HPA HPA:0250000 hippocampus 0.0227394941031268 6678 25 22 0.88 0.00329439952081462
HPA HPA:0100133 cerebral cortex; neuronal cells[High] 0.0232808333869879 1785 8 5 0.625 0.00280112044817927
HPA HPA:0620222 vagina; squamous epithelial cells[≥Medium] 0.0241234569940582 3945 29 18 0.620689655172414 0.00456273764258555
HPA HPA:0090922 cerebellum; GLUC cells - cytoplasm/membrane[≥Medium] 0.0241783702304369 179 21 3 0.142857142857143 0.0167597765363128
HPA HPA:0420051 salivary gland; glandular cells[≥Low] 0.024800666057955 6744 29 25 0.862068965517241 0.00370699881376038
HPA HPA:0420000 salivary gland 0.024800666057955 6744 29 25 0.862068965517241 0.00370699881376038
HPA HPA:0050053 breast; glandular cells[High] 0.0259854936438526 1299 29 9 0.310344827586207 0.0069284064665127
HPA HPA:0110000 cervix, uterine 0.0259854936438526 6778 25 22 0.88 0.00324579521982886
HPA HPA:0350471 pancreas; exocrine glandular cells[≥Low] 0.0259854936438526 6778 25 22 0.88 0.00324579521982886
HPA HPA:0530000 spleen 0.0259854936438526 5756 25 20 0.8 0.00347463516330785
HPA HPA:0090921 cerebellum; GLUC cells - cytoplasm/membrane[≥Low] 0.0283585046500304 197 21 3 0.142857142857143 0.0152284263959391
HPA HPA:0050052 breast; glandular cells[≥Medium] 0.0289613816099137 4971 23 17 0.739130434782609 0.00341983504325086
HPA HPA:0160252 endometrium 1; cells in endometrial stroma[≥Medium] 0.0289613816099137 2142 29 12 0.413793103448276 0.00560224089635854
HPA HPA:0400052 rectum; glandular cells[≥Medium] 0.0302573177682188 6410 29 24 0.827586206896552 0.00374414976599064
HPA HPA:0040000 bone marrow 0.0304448166646698 6349 25 21 0.84 0.00330760749724366
HPA HPA:0040081 bone marrow; hematopoietic cells[≥Low] 0.0304448166646698 6349 25 21 0.84 0.00330760749724366
HPA HPA:0160000 endometrium 1 0.031259211272815 6894 25 22 0.88 0.00319118073687264
HPA HPA:0080131 caudate; neuronal cells[≥Low] 0.0336172743124009 6042 29 23 0.793103448275862 0.00380668652763985
HPA HPA:0320101 nasopharynx; respiratory epithelial cells[≥Low] 0.0366244149072028 6079 29 23 0.793103448275862 0.00378351702582662
HPA HPA:0390051 prostate; glandular cells[≥Low] 0.0378539026813854 6528 29 24 0.827586206896552 0.00367647058823529
HPA HPA:0390000 prostate 0.0378539026813854 6528 29 24 0.827586206896552 0.00367647058823529
HPA HPA:0600433 tonsil; germinal center cells[High] 0.0412270343391922 1179 29 8 0.275862068965517 0.00678541136556404
HPA HPA:0190000 esophagus 0.0412270343391922 6524 25 21 0.84 0.00321888412017167
HPA HPA:0480053 small intestine; glandular cells[High] 0.0412270343391922 2723 14 8 0.571428571428571 0.00293793609988983
HPA HPA:0310432 lymph node; germinal center cells[≥Medium] 0.0412270343391922 3209 29 15 0.517241379310345 0.00467435338111561
HPA HPA:0190221 esophagus; squamous epithelial cells[≥Low] 0.0412270343391922 6524 25 21 0.84 0.00321888412017167
HPA HPA:0210053 fallopian tube; glandular cells[High] 0.0433381441251159 1728 29 10 0.344827586206897 0.00578703703703704
HPA HPA:0170051 endometrium 2; glandular cells[≥Low] 0.0447222404746801 6568 25 21 0.84 0.0031973203410475
HPA HPA:0610831 urinary bladder; urothelial cells[≥Low] 0.0451274068087593 7141 16 15 0.9375 0.00210054614199692
HPA HPA:0610000 urinary bladder 0.0451274068087593 7141 16 15 0.9375 0.00210054614199692
HPA HPA:0030051 appendix; glandular cells[≥Low] 0.0451274068087593 7142 16 15 0.9375 0.00210025203024363
HPA HPA:0170052 endometrium 2; glandular cells[≥Medium] 0.0487138396129539 4758 25 17 0.68 0.003572929802438
HPA HPA:0460641 skin 1; Langerhans[≥Low] 0.0487138396129539 4634 13 10 0.769230769230769 0.00215796288303841
KEGG KEGG:03010 Ribosome 2.00795440627879e-44 153 29 27 0.931034482758621 0.176470588235294
KEGG KEGG:05171 Coronavirus disease - COVID-19 1.57375513697562e-39 231 29 27 0.931034482758621 0.116883116883117
MIRNA MIRNA:hsa-miR-484 hsa-miR-484 0.000414775722505177 890 15 8 0.533333333333333 0.00898876404494382
MIRNA MIRNA:hsa-miR-92a-3p hsa-miR-92a-3p 0.000641785281196343 1404 27 12 0.444444444444444 0.00854700854700855
MIRNA MIRNA:hsa-miR-331-3p hsa-miR-331-3p 0.00105017497952329 403 18 6 0.333333333333333 0.0148883374689826
MIRNA MIRNA:hsa-miR-16-5p hsa-miR-16-5p 0.00145452514904575 1556 28 12 0.428571428571429 0.0077120822622108
MIRNA MIRNA:hsa-miR-652-3p hsa-miR-652-3p 0.00145452514904575 162 5 3 0.6 0.0185185185185185
MIRNA MIRNA:hsa-miR-615-3p hsa-miR-615-3p 0.00316215303251431 891 29 9 0.310344827586207 0.0101010101010101
MIRNA MIRNA:hsa-miR-1180-3p hsa-miR-1180-3p 0.0137520971261148 67 24 3 0.125 0.0447761194029851
MIRNA MIRNA:hsa-miR-30c-5p hsa-miR-30c-5p 0.0160604804258528 519 17 5 0.294117647058824 0.00963391136801541
MIRNA MIRNA:hsa-miR-186-5p hsa-miR-186-5p 0.0160604804258528 749 19 6 0.315789473684211 0.00801068090787717
MIRNA MIRNA:hsa-miR-548c-3p hsa-miR-548c-3p 0.0224537913228502 519 6 3 0.5 0.00578034682080925
MIRNA MIRNA:hsa-miR-100-5p hsa-miR-100-5p 0.0224537913228502 250 24 4 0.166666666666667 0.016
MIRNA MIRNA:hsa-miR-4477a hsa-miR-4477a 0.0224537913228502 139 17 3 0.176470588235294 0.0215827338129496
MIRNA MIRNA:hsa-miR-4685-5p hsa-miR-4685-5p 0.0224537913228502 124 23 3 0.130434782608696 0.0241935483870968
MIRNA MIRNA:hsa-miR-877-5p hsa-miR-877-5p 0.0224537913228502 233 10 3 0.3 0.0128755364806867
MIRNA MIRNA:hsa-miR-6837-5p hsa-miR-6837-5p 0.0224537913228502 123 23 3 0.130434782608696 0.024390243902439
MIRNA MIRNA:hsa-miR-4436b-3p hsa-miR-4436b-3p 0.0243492199774343 136 23 3 0.130434782608696 0.0220588235294118
MIRNA MIRNA:hsa-miR-7843-5p hsa-miR-7843-5p 0.0243492199774343 132 23 3 0.130434782608696 0.0227272727272727
MIRNA MIRNA:hsa-miR-296-3p hsa-miR-296-3p 0.0243492199774343 255 13 3 0.230769230769231 0.0117647058823529
MIRNA MIRNA:hsa-miR-6879-5p hsa-miR-6879-5p 0.0243492199774343 137 23 3 0.130434782608696 0.0218978102189781
MIRNA MIRNA:hsa-miR-6735-5p hsa-miR-6735-5p 0.0243492199774343 134 23 3 0.130434782608696 0.0223880597014925
MIRNA MIRNA:hsa-miR-4632-5p hsa-miR-4632-5p 0.0243492199774343 132 23 3 0.130434782608696 0.0227272727272727
MIRNA MIRNA:hsa-miR-544a hsa-miR-544a 0.0246745041425847 151 23 3 0.130434782608696 0.0198675496688742
MIRNA MIRNA:hsa-miR-7113-5p hsa-miR-7113-5p 0.0246745041425847 148 23 3 0.130434782608696 0.0202702702702703
MIRNA MIRNA:hsa-miR-125b-5p hsa-miR-125b-5p 0.0261706395210054 427 9 3 0.333333333333333 0.00702576112412178
MIRNA MIRNA:hsa-miR-744-5p hsa-miR-744-5p 0.0363287389912602 435 10 3 0.3 0.00689655172413793
MIRNA MIRNA:hsa-miR-27a-3p hsa-miR-27a-3p 0.0435295206614454 427 12 3 0.25 0.00702576112412178
MIRNA MIRNA:hsa-miR-320a hsa-miR-320a 0.0484854379306652 584 29 5 0.172413793103448 0.00856164383561644
REAC REAC:R-HSA-156902 Peptide chain elongation 1.25201380949562e-56 90 29 28 0.96551724137931 0.311111111111111
REAC REAC:R-HSA-156842 Eukaryotic Translation Elongation 2.64777376095922e-56 94 29 28 0.96551724137931 0.297872340425532
REAC REAC:R-HSA-192823 Viral mRNA Translation 9.69556035791355e-54 90 29 27 0.931034482758621 0.3
REAC REAC:R-HSA-2408557 Selenocysteine synthesis 2.31276553610655e-53 94 29 27 0.931034482758621 0.287234042553192
REAC REAC:R-HSA-72764 Eukaryotic Translation Termination 2.31276553610655e-53 94 29 27 0.931034482758621 0.287234042553192
REAC REAC:R-HSA-975956 Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC) 3.74478506660195e-53 96 29 27 0.931034482758621 0.28125
REAC REAC:R-HSA-72689 Formation of a pool of free 40S subunits 1.87610398155426e-52 102 29 27 0.931034482758621 0.264705882352941
REAC REAC:R-HSA-9633012 Response of EIF2AK4 (GCN2) to amino acid deficiency 1.87610398155426e-52 102 29 27 0.931034482758621 0.264705882352941
REAC REAC:R-HSA-156827 L13a-mediated translational silencing of Ceruloplasmin expression 3.0105390816947e-51 112 29 27 0.931034482758621 0.241071428571429
REAC REAC:R-HSA-72706 GTP hydrolysis and joining of the 60S ribosomal subunit 3.23589042301718e-51 113 29 27 0.931034482758621 0.238938053097345
REAC REAC:R-HSA-1799339 SRP-dependent cotranslational protein targeting to membrane 3.23589042301718e-51 113 29 27 0.931034482758621 0.238938053097345
REAC REAC:R-HSA-927802 Nonsense-Mediated Decay (NMD) 6.10760591074522e-51 116 29 27 0.931034482758621 0.232758620689655
REAC REAC:R-HSA-975957 Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC) 6.10760591074522e-51 116 29 27 0.931034482758621 0.232758620689655
REAC REAC:R-HSA-2408522 Selenoamino acid metabolism 7.37138961967658e-51 117 29 27 0.931034482758621 0.230769230769231
REAC REAC:R-HSA-72737 Cap-dependent Translation Initiation 1.39512941333181e-50 120 29 27 0.931034482758621 0.225
REAC REAC:R-HSA-72613 Eukaryotic Translation Initiation 1.39512941333181e-50 120 29 27 0.931034482758621 0.225
REAC REAC:R-HSA-168273 Influenza Viral RNA Transcription and Replication 2.93896071916222e-49 133 29 27 0.931034482758621 0.203007518796992
REAC REAC:R-HSA-168255 Influenza Infection 1.48483996626208e-47 152 29 27 0.931034482758621 0.177631578947368
REAC REAC:R-HSA-9711097 Cellular response to starvation 3.65970767174047e-47 157 29 27 0.931034482758621 0.171974522292994
REAC REAC:R-HSA-9010553 Regulation of expression of SLITs and ROBOs 4.27478190906976e-46 171 29 27 0.931034482758621 0.157894736842105
REAC REAC:R-HSA-6791226 Major pathway of rRNA processing in the nucleolus and cytosol 2.94498777029353e-45 183 29 27 0.931034482758621 0.147540983606557
REAC REAC:R-HSA-8868773 rRNA processing in the nucleus and cytosol 1.31717270565206e-44 193 29 27 0.931034482758621 0.139896373056995
REAC REAC:R-HSA-72312 rRNA processing 5.42808638400768e-44 203 29 27 0.931034482758621 0.133004926108374
REAC REAC:R-HSA-376176 Signaling by ROBO receptors 3.54818423818603e-43 217 29 27 0.931034482758621 0.124423963133641
REAC REAC:R-HSA-72766 Translation 2.93385347488868e-42 292 29 28 0.96551724137931 0.0958904109589041
REAC REAC:R-HSA-71291 Metabolism of amino acids and derivatives 1.01111932465772e-36 368 29 27 0.931034482758621 0.0733695652173913
REAC REAC:R-HSA-2262752 Cellular responses to stress 2.03737455750974e-34 546 29 28 0.96551724137931 0.0512820512820513
REAC REAC:R-HSA-8953897 Cellular responses to external stimuli 4.05822714315307e-34 560 29 28 0.96551724137931 0.05
REAC REAC:R-HSA-422475 Axon guidance 5.95986690061191e-32 549 29 27 0.931034482758621 0.0491803278688525
REAC REAC:R-HSA-9675108 Nervous system development 1.96370120612243e-31 574 29 27 0.931034482758621 0.0470383275261324
REAC REAC:R-HSA-8953854 Metabolism of RNA 8.09381244689657e-30 658 29 27 0.931034482758621 0.0410334346504559
REAC REAC:R-HSA-5663205 Infectious disease 2.72827514669647e-27 815 29 27 0.931034482758621 0.0331288343558282
REAC REAC:R-HSA-1266738 Developmental Biology 4.23539062372586e-24 1069 29 27 0.931034482758621 0.0252572497661366
REAC REAC:R-HSA-1643685 Disease 4.55704752554197e-20 1509 29 27 0.931034482758621 0.0178926441351889
REAC REAC:R-HSA-392499 Metabolism of proteins 7.98702287598337e-19 1961 29 28 0.96551724137931 0.014278429372769
REAC REAC:R-HSA-72695 Formation of the ternary complex, and subsequently, the 43S complex 2.96586726902818e-18 52 28 11 0.392857142857143 0.211538461538462
REAC REAC:R-HSA-72702 Ribosomal scanning and start codon recognition 1.28839534174665e-17 59 28 11 0.392857142857143 0.186440677966102
REAC REAC:R-HSA-72649 Translation initiation complex formation 1.28839534174665e-17 59 28 11 0.392857142857143 0.186440677966102
REAC REAC:R-HSA-72662 Activation of the mRNA upon binding of the cap-binding complex and eIFs, and subsequent binding to 43S 1.53489208647834e-17 60 28 11 0.392857142857143 0.183333333333333
REAC REAC:R-HSA-1430728 Metabolism 1.85802263260729e-16 2070 29 27 0.931034482758621 0.0130434782608696
REAC REAC:R-HSA-6790901 rRNA modification in the nucleus and cytosol 0.00493475177815849 60 28 3 0.107142857142857 0.05
TF TF:M02073_1 Factor: Fli-1; motif: ACCGGAAGYN; match class: 1 0.000933647929631741 1488 12 8 0.666666666666667 0.00537634408602151
TF TF:M04714 Factor: Elf-1; motif: ACTTCCGGG 0.000933647929631741 7798 29 25 0.862068965517241 0.00320595024365222
TF TF:M02053_1 Factor: ELF1; motif: NCCGGAARTN; match class: 1 0.00143956672966416 1559 13 8 0.615384615384615 0.00513149454778704
TF TF:M00025_1 Factor: Elk-1; motif: NNNNCCGGAARTNN; match class: 1 0.00143956672966416 4639 14 12 0.857142857142857 0.00258676438887691
TF TF:M08913_1 Factor: FLI-1; motif: NAYTTCCGGT; match class: 1 0.00143956672966416 3055 13 10 0.769230769230769 0.00327332242225859
TF TF:M02067_1 Factor: ER71; motif: ACCGGAARYN; match class: 1 0.00143956672966416 1619 13 8 0.615384615384615 0.00494132180358246
TF TF:M11392_1 Factor: Erg; motif: NACCGGAARYN; match class: 1 0.00168342819128953 3233 13 10 0.769230769230769 0.00309310238168883
TF TF:M11396_1 Factor: Erg; motif: NACCGGAARTN; match class: 1 0.00206547914764745 4963 14 12 0.857142857142857 0.00241789240378803
TF TF:M08760_1 Factor: ETV7; motif: NNSCGGAAGTR; match class: 1 0.00215573741833007 326 8 4 0.5 0.0122699386503067
TF TF:M02052_1 Factor: EHF; motif: CSCGGAARTN; match class: 1 0.00215573741833007 4056 14 11 0.785714285714286 0.0027120315581854
TF TF:M08913 Factor: FLI-1; motif: NAYTTCCGGT 0.00215573741833007 8322 27 23 0.851851851851852 0.00276375871184811
TF TF:M09905 Factor: SAP-1; motif: NNCCGGAAGTGN 0.00215573741833007 8273 27 23 0.851851851851852 0.00278012812764414
TF TF:M02071_1 Factor: ETV7; motif: NCCGGAANNN; match class: 1 0.00218666911776796 4465 29 18 0.620689655172414 0.00403135498320269
TF TF:M00025 Factor: Elk-1; motif: NNNNCCGGAARTNN 0.00232188573419664 10262 27 25 0.925925925925926 0.00243617228610407
TF TF:M11400_1 Factor: Fli-1; motif: NACCGGAARTN; match class: 1 0.00232188573419664 4201 14 11 0.785714285714286 0.00261842418471792
TF TF:M09992 Factor: c-Myc; motif: NCCACGTGCNN 0.00232188573419664 5627 29 20 0.689655172413793 0.00355429180735738
TF TF:M02059 Factor: ELK-1; motif: ACCGGAAGTN 0.0024466958135771 9423 27 24 0.888888888888889 0.00254695956701687
TF TF:M09606 Factor: nerf; motif: NRRNSCGGAAGNRNNNN 0.0024466958135771 6249 18 15 0.833333333333333 0.00240038406144983
TF TF:M03982 Factor: ETV4; motif: ACCGGAAGTN 0.0024466958135771 6826 14 13 0.928571428571429 0.00190448285965426
TF TF:M03988_1 Factor: FLI1; motif: ACCGGAARTN; match class: 1 0.00353461860320847 2950 13 9 0.692307692307692 0.00305084745762712
TF TF:M08875 Factor: E2F; motif: NNTTTCGCGCN 0.00353461860320847 6203 15 13 0.866666666666667 0.00209576011607287
TF TF:M11414_1 Factor: GABP-alpha; motif: NACCGGAAGTN; match class: 1 0.00353703434843182 442 8 4 0.5 0.00904977375565611
TF TF:M03966 Factor: ELF1; motif: AACCCGGAAGTR 0.00353703434843182 6610 25 19 0.76 0.00287443267776097
TF TF:M03975_1 Factor: ERG; motif: ACCGGAARTN; match class: 1 0.00380969055333989 4024 13 10 0.769230769230769 0.00248508946322068
TF TF:M08451_1 Factor: Elk-1:HOXA1; motif: ACCGGAAGTAATTA; match class: 1 0.00380969055333989 2584 15 9 0.6 0.00348297213622291
TF TF:M03983_1 Factor: ETV5; motif: NCCGGAWGYN; match class: 1 0.00380969055333989 537 8 4 0.5 0.0074487895716946
TF TF:M03967 Factor: ELF3; motif: WACCCGGAAGTAN 0.00380969055333989 7610 14 13 0.928571428571429 0.00170827858081472
TF TF:M02062_1 Factor: Erg; motif: ACCGGAAGTN; match class: 1 0.00380969055333989 2718 12 8 0.666666666666667 0.00294334069168506
TF TF:M10758 Factor: HOXB1; motif: NTCRTTAN 0.00380969055333989 2781 9 7 0.777777777777778 0.0025170801869831
TF TF:M11396 Factor: Erg; motif: NACCGGAARTN 0.00380969055333989 10765 27 25 0.925925925925926 0.002322340919647
TF TF:M09904 Factor: Elk-1; motif: RCCGGAAGTGN 0.00380969055333989 8164 27 22 0.814814814814815 0.00269475747182754
TF TF:M02069 Factor: Erm; motif: ACCGGAAGTN 0.00380969055333989 6892 13 12 0.923076923076923 0.00174114915844457
TF TF:M11451 Factor: Elf-1; motif: NANCCGGAAGTN 0.00380969055333989 6886 25 19 0.76 0.00275922160906186
TF TF:M03977_1 Factor: ETS1; motif: ACCGGAARYN; match class: 1 0.00380969055333989 4677 14 11 0.785714285714286 0.00235193500106906
TF TF:M10643 Factor: Homeobox; motif: NCAMTTANC 0.00380969055333989 3983 21 13 0.619047619047619 0.00326387145367813
TF TF:M11415_1 Factor: GABP-alpha; motif: NRCCGGAAGTN; match class: 1 0.00380969055333989 546 8 4 0.5 0.00732600732600733
TF TF:M03990_1 Factor: GABPA; motif: ACCGGAAGTN; match class: 1 0.00380969055333989 1206 12 6 0.5 0.00497512437810945
TF TF:M02074_1 Factor: GABPalpha; motif: RCCGGAWRYN; match class: 1 0.00380969055333989 1005 13 6 0.461538461538462 0.00597014925373134
TF TF:M02065 Factor: ER81; motif: RCCGGAARYN 0.00380969055333989 12550 29 28 0.96551724137931 0.00223107569721116
TF TF:M02065_1 Factor: ER81; motif: RCCGGAARYN; match class: 1 0.00380969055333989 6749 20 16 0.8 0.00237072158838346
TF TF:M11218 Factor: CREB1; motif: NRTGAYGCGTN 0.00380969055333989 8461 28 23 0.821428571428571 0.00271835480439664
TF TF:M11420_1 Factor: ER81; motif: NACCGGAAGTN; match class: 1 0.00380969055333989 494 8 4 0.5 0.00809716599190283
TF TF:M11404_1 Factor: Fli-1; motif: NACCGGAARTN; match class: 1 0.00380969055333989 3171 13 9 0.692307692307692 0.00283822138126774
TF TF:M04696_1 Factor: YY1; motif: GCCGCCATNTTGNNNNNGGNCN; match class: 1 0.00380969055333989 1973 27 11 0.407407407407407 0.00557526609224531
TF TF:M02063 Factor: c-ets-1; motif: ACCGGAWGTN 0.00380969055333989 7600 27 21 0.777777777777778 0.00276315789473684
TF TF:M11424 Factor: Erm; motif: NNSCGGAWGYN 0.00380969055333989 8149 29 23 0.793103448275862 0.00282243220026997
TF TF:M01752_1 Factor: ERG; motif: ACCGGAART; match class: 1 0.00380969055333989 3705 12 9 0.75 0.00242914979757085
TF TF:M02070_1 Factor: TEL1; motif: CNCGGAANNN; match class: 1 0.00380969055333989 4841 14 11 0.785714285714286 0.00227225779797562
TF TF:M01165 Factor: Elk-1; motif: RACCGGAAGTR 0.00397411517320599 7773 25 20 0.8 0.00257300913418243
TF TF:M09904_1 Factor: Elk-1; motif: RCCGGAAGTGN; match class: 1 0.00397411517320599 2743 12 8 0.666666666666667 0.002916514764856
TF TF:M10785 Factor: hoxa9; motif: RTCGTWANNN 0.00405967560758798 5632 27 18 0.666666666666667 0.00319602272727273
TF TF:M04810 Factor: USF2; motif: AAGTCACG 0.00405967560758798 5496 17 13 0.764705882352941 0.00236535662299854
TF TF:M04698_1 Factor: GABP-alpha; motif: CACTTCCGG; match class: 1 0.00417208005611444 576 8 4 0.5 0.00694444444444444
TF TF:M08760 Factor: ETV7; motif: NNSCGGAAGTR 0.00419663101606493 2349 17 9 0.529411764705882 0.00383141762452107
TF TF:M08910 Factor: C/EBPBETA; motif: KRTTGCGYAAY 0.00465087785625969 4674 17 12 0.705882352941177 0.00256739409499358
TF TF:M11221 Factor: CREB1; motif: RTGACGYGTCAN 0.00465087785625969 9677 25 22 0.88 0.00227343184871344
TF TF:M02068_1 Factor: etv3; motif: ACCGGAAGYN; match class: 1 0.00465087785625969 613 8 4 0.5 0.0065252854812398
TF TF:M03983 Factor: ETV5; motif: NCCGGAWGYN 0.00465087785625969 3129 14 9 0.642857142857143 0.00287631831255992
TF TF:M09900 Factor: Elf-1; motif: NNANCCGGAAGTGS 0.00465087785625969 5219 29 18 0.620689655172414 0.00344893657788848
TF TF:M09935 Factor: GABP-alpha; motif: NNNRCCGGAAGTGN 0.00465087785625969 4420 25 15 0.6 0.00339366515837104
TF TF:M08339 Factor: HOXB2:Elf-1; motif: SCGGAAGTMRTTA 0.00465087785625969 1690 18 8 0.444444444444444 0.00473372781065089
TF TF:M11447_1 Factor: Elf-1; motif: NAMCCGGAAGTN; match class: 1 0.00471326168828664 2593 13 8 0.615384615384615 0.00308522946394138
TF TF:M11382_1 Factor: ESE-1; motif: NWTRCGGAWGCN; match class: 1 0.00471326168828664 4112 14 10 0.714285714285714 0.00243190661478599
TF TF:M02073 Factor: Fli-1; motif: ACCGGAAGYN 0.00471326168828664 5839 13 11 0.846153846153846 0.00188388422675116
TF TF:M00916_1 Factor: CREB; motif: NNTKACGTCANNNS; match class: 1 0.00471326168828664 1692 14 7 0.5 0.0041371158392435
TF TF:M11434_1 Factor: Elk-1; motif: NRSCGGAAGNN; match class: 1 0.00471326168828664 2935 12 8 0.666666666666667 0.00272572402044293
TF TF:M08413_1 Factor: TEF-3:C/EBPdelta; motif: RGWATGYNRTTRCGYAAY; match class: 1 0.00471326168828664 1604 7 5 0.714285714285714 0.00311720698254364
TF TF:M02070 Factor: TEL1; motif: CNCGGAANNN 0.00471326168828664 10837 29 26 0.896551724137931 0.00239918796714958
TF TF:M11428 Factor: PEA3; motif: NACCGGAAGTN 0.00471326168828664 7186 25 19 0.76 0.00264403005844698
TF TF:M01752 Factor: ERG; motif: ACCGGAART 0.00478352995403687 9474 27 23 0.851851851851852 0.00242769685454929
TF TF:M11430 Factor: PEA3; motif: NACCGGAAGTN 0.00478352995403687 10865 29 26 0.896551724137931 0.00239300506212609
TF TF:M01660_1 Factor: GABP-alpha; motif: CTTCCK; match class: 1 0.00480835414492722 5133 25 16 0.64 0.00311708552503409
TF TF:M08345 Factor: HOXB2:PEA3; motif: ACCGGAAATGRN 0.00480835414492722 8027 14 13 0.928571428571429 0.00161953407250529
TF TF:M01866 Factor: C/EBPalpha; motif: NNNTTNNGCAANN 0.00495323609189306 5089 23 15 0.652173913043478 0.00294753389663981
TF TF:M11218_1 Factor: CREB1; motif: NRTGAYGCGTN; match class: 1 0.00495323609189306 2438 21 10 0.476190476190476 0.00410172272354389
TF TF:M02062 Factor: Erg; motif: ACCGGAAGTN 0.00495323609189306 8056 14 13 0.928571428571429 0.0016137040714995
TF TF:M02056 Factor: ELF4; motif: NCCGGAARTN 0.00495323609189306 5332 29 18 0.620689655172414 0.00337584396099025
TF TF:M11451_1 Factor: Elf-1; motif: NANCCGGAAGTN; match class: 1 0.00495323609189306 2112 12 7 0.583333333333333 0.00331439393939394
TF TF:M11414 Factor: GABP-alpha; motif: NACCGGAAGTN 0.00497944656974555 2907 25 12 0.48 0.00412796697626419
TF TF:M08223_1 Factor: Elk-1:OC-2; motif: RCCGGAASCGATCGATNN; match class: 1 0.00505619887819534 5853 25 17 0.68 0.00290449342217666
TF TF:M11419_1 Factor: ER81; motif: NNCCGGAWGYN; match class: 1 0.00515080118185741 1427 12 6 0.5 0.00420462508759636
TF TF:M02052 Factor: EHF; motif: CSCGGAARTN 0.00515080118185741 10107 29 25 0.862068965517241 0.00247353319481547
TF TF:M11433 Factor: Elk-1; motif: NRCCGGAAGTN 0.00515080118185741 7679 16 14 0.875 0.00182315405651778
TF TF:M11407 Factor: Pet-1; motif: NACCGGAAGTN 0.00515080118185741 772 13 5 0.384615384615385 0.00647668393782383
TF TF:M11449_1 Factor: Elf-1; motif: NANCCGGAAGTN; match class: 1 0.00541573253743383 695 8 4 0.5 0.00575539568345324
TF TF:M01660 Factor: GABP-alpha; motif: CTTCCK 0.0056672945904377 11116 21 20 0.952380952380952 0.00179920834832674
TF TF:M02066 Factor: PEA3; motif: RCCGGAAGYN 0.00579134962451632 7045 17 14 0.823529411764706 0.00198722498225692
TF TF:M11425 Factor: PEA3; motif: NACCGGAAGTN 0.00579134962451632 7428 25 19 0.76 0.00255788906838988
TF TF:M11422 Factor: Erm; motif: NRCMGGAAGTN 0.00579134962451632 4669 25 15 0.6 0.00321267937459842
TF TF:M03988 Factor: FLI1; motif: ACCGGAARTN 0.00586630333081584 8318 14 13 0.928571428571429 0.00156287569127194
TF TF:M04690_1 Factor: C/EBPbeta; motif: RTTGCGCAA; match class: 1 0.0059590160621664 3547 22 12 0.545454545454545 0.0033831406822667
TF TF:M01258 Factor: GABP; motif: CACTTCCGGNNN 0.0059590160621664 2838 13 8 0.615384615384615 0.00281888653981677
TF TF:M11437_1 Factor: SAP-1; motif: NRCCGGAWGYN; match class: 1 0.0059590160621664 456 12 4 0.333333333333333 0.0087719298245614
TF TF:M00485_1 Factor: Nkx2-2; motif: TTAAGTRSTT; match class: 1 0.0059590160621664 304 7 3 0.428571428571429 0.00986842105263158
TF TF:M03791 Factor: GABPalpha_GABPbeta; motif: CTTCCKGY 0.00607821585770661 2969 29 13 0.448275862068966 0.00437857864600876
TF TF:M02068 Factor: etv3; motif: ACCGGAAGYN 0.00613985086882366 3443 14 9 0.642857142857143 0.00261399941911124
TF TF:M02066_1 Factor: PEA3; motif: RCCGGAAGYN; match class: 1 0.00613985086882366 2283 12 7 0.583333333333333 0.00306614104248795
TF TF:M02058 Factor: SAP1A; motif: NCCGGAARYN 0.00639638991311786 842 13 5 0.384615384615385 0.00593824228028504
TF TF:M08451 Factor: Elk-1:HOXA1; motif: ACCGGAAGTAATTA 0.00651280659937082 8421 17 15 0.882352941176471 0.00178126113288208
TF TF:M11316 Factor: C/EBPbeta; motif: NRTTGCGYAAYN 0.00653476068719031 5225 28 17 0.607142857142857 0.00325358851674641
TF TF:M02044_1 Factor: YY1; motif: GCCGCCATTTTG; match class: 1 0.00653476068719031 1198 27 8 0.296296296296296 0.00667779632721202
TF TF:M02056_1 Factor: ELF4; motif: NCCGGAARTN; match class: 1 0.0066561940756578 1291 14 6 0.428571428571429 0.00464756003098373
TF TF:M11425_1 Factor: PEA3; motif: NACCGGAAGTN; match class: 1 0.0066561940756578 2330 12 7 0.583333333333333 0.00300429184549356
TF TF:M01482 Factor: Nkx3-2; motif: NNNAACCACTTAANNAN 0.00744824525555549 3670 28 14 0.5 0.00381471389645777
TF TF:M10644 Factor: Homeobox; motif: NCAMTTANC 0.00753749844148665 3682 28 14 0.5 0.00380228136882129
TF TF:M02063_1 Factor: c-ets-1; motif: ACCGGAWGTN; match class: 1 0.00753749844148665 2396 12 7 0.583333333333333 0.00292153589315526
TF TF:M10880_1 Factor: Alx-4; motif: NNCRTTAN; match class: 1 0.00753749844148665 2683 11 7 0.636363636363636 0.00260901975400671
TF TF:M07415_1 Factor: Elf-1; motif: AWCCCGGAAGTN; match class: 1 0.00753749844148665 2397 12 7 0.583333333333333 0.00292031706299541
TF TF:M12275_1 Factor: YY1; motif: NGCCGCCATYTTGN; match class: 1 0.00760194319274426 1600 27 9 0.333333333333333 0.005625
TF TF:M11400 Factor: Fli-1; motif: NACCGGAARTN 0.00760194319274426 9946 27 23 0.851851851851852 0.00231248743213352
TF TF:M09600 Factor: CREB1; motif: TKACGTCAYNN 0.00760194319274426 5324 28 17 0.607142857142857 0.00319308790383171
TF TF:M09605 Factor: Elf-1; motif: NAANCMGGAAGTGN 0.00786680285279502 5778 14 11 0.785714285714286 0.00190377293181032
TF TF:M11392 Factor: Erg; motif: NACCGGAARYN 0.00786680285279502 8690 14 13 0.928571428571429 0.00149597238204833
TF TF:M11447 Factor: Elf-1; motif: NAMCCGGAAGTN 0.00786680285279502 7703 25 19 0.76 0.00246657146566273
TF TF:M02055 Factor: ESE-1; motif: NSMGGAARTN 0.00790841091140156 7559 29 21 0.724137931034483 0.00277814525730917
TF TF:M03975 Factor: ERG; motif: ACCGGAARTN 0.00790841091140156 10002 27 23 0.851851851851852 0.0022995400919816
TF TF:M01078_1 Factor: c-Ets-1; motif: NNNRCCGGAWRYNNNN; match class: 1 0.00790841091140156 2448 12 7 0.583333333333333 0.00285947712418301
TF TF:M01078 Factor: c-Ets-1; motif: NNNRCCGGAWRYNNNN 0.00790841091140156 7544 29 21 0.724137931034483 0.00278366914103924
TF TF:M01214 Factor: ESE-1; motif: NSMGGAARTN 0.00790841091140156 7559 29 21 0.724137931034483 0.00277814525730917
TF TF:M11452_1 Factor: Elf-1; motif: NANGCGGAAGTR; match class: 1 0.0079578978628787 1696 8 5 0.625 0.00294811320754717
TF TF:M04698 Factor: GABP-alpha; motif: CACTTCCGG 0.0079578978628787 3196 25 12 0.48 0.00375469336670839
TF TF:M11404 Factor: Fli-1; motif: NACCGGAARTN 0.0079578978628787 8743 14 13 0.928571428571429 0.00148690380876129
TF TF:M08222 Factor: Elk-1:HOXB13; motif: ACCGGAAGTNGTAAAN 0.00799371179420193 7653 27 20 0.740740740740741 0.00261335424016725
TF TF:M11530_1 Factor: E2F-2; motif: NWTTTGGCGCCAWWNN; match class: 1 0.00811794093339273 13449 29 28 0.96551724137931 0.00208193917763402
TF TF:M11448 Factor: Elf-1; motif: NANGCGGAAGTN 0.00824590787430205 7600 29 21 0.724137931034483 0.00276315789473684
TF TF:M03990 Factor: GABPA; motif: ACCGGAAGTN 0.00827747381942343 5258 13 10 0.769230769230769 0.00190186382655002
TF TF:M11427 Factor: PEA3; motif: NACCGGAAGTN 0.00831340790195399 10585 29 25 0.862068965517241 0.00236183278223902
TF TF:M10849_1 Factor: Cdx-2; motif: NRTCGTAANNNN; match class: 1 0.00831340790195399 4497 27 15 0.555555555555556 0.00333555703802535
TF TF:M02067 Factor: ER71; motif: ACCGGAARYN 0.00884945672382477 5930 14 11 0.785714285714286 0.00185497470489039
TF TF:M08413 Factor: TEF-3:C/EBPdelta; motif: RGWATGYNRTTRCGYAAY 0.00884945672382477 6035 7 7 1 0.00115990057995029
TF TF:M02071 Factor: ETV7; motif: NCCGGAANNN 0.00884945672382477 10116 27 23 0.851851851851852 0.00227362593910637
TF TF:M11415 Factor: GABP-alpha; motif: NRCCGGAAGTN 0.00884945672382477 3257 25 12 0.48 0.00368437212158428
TF TF:M03970 Factor: ELK1; motif: ACCGGAAGTN 0.00897447154199021 4782 14 10 0.714285714285714 0.00209117524048515
TF TF:M11436 Factor: SAP-1; motif: NRNCGGAWRYN 0.00897447154199021 1431 14 6 0.428571428571429 0.00419287211740042
TF TF:M10795 Factor: HOXA10; motif: NGTCGTAAAAN 0.00905999187924074 6913 18 14 0.777777777777778 0.00202516996962245
TF TF:M03966_1 Factor: ELF1; motif: AACCCGGAAGTR; match class: 1 0.00916755002809599 1577 23 8 0.347826086956522 0.00507292327203551
TF TF:M11435 Factor: Elk-1; motif: NNCCGGAAGTN 0.00932821996831423 11728 21 20 0.952380952380952 0.00170532060027285
TF TF:M00144_1 Factor: Pax-5; motif: RRMSWGANWYCTNRAGCGKRACSRYNSM; match class: 1 0.00955124646909924 7128 25 18 0.72 0.00252525252525253
TF TF:M01770_1 Factor: XBP-1; motif: WNNGMCACGTC; match class: 1 0.00960373927505489 4554 22 13 0.590909090909091 0.0028546332894159
TF TF:M03970_1 Factor: ELK1; motif: ACCGGAAGTN; match class: 1 0.00960373927505489 1097 12 5 0.416666666666667 0.00455788514129444
TF TF:M11217 Factor: CREB1; motif: NRTGACGYN 0.00960373927505489 2783 29 12 0.413793103448276 0.00431189363995688
TF TF:M01167 Factor: SAP-1a; motif: NACCGGAAGTV 0.00960373927505489 1948 29 10 0.344827586206897 0.00513347022587269
TF TF:M02053 Factor: ELF1; motif: NCCGGAARTN 0.00960373927505489 6033 14 11 0.785714285714286 0.00182330515498094
TF TF:M11422_1 Factor: Erm; motif: NRCMGGAAGTN; match class: 1 0.00960373927505489 934 8 4 0.5 0.00428265524625268
TF TF:M01229_1 Factor: GTF2IRD1-isoform2; motif: GGGATTRNR; match class: 1 0.00960373927505489 9375 27 22 0.814814814814815 0.00234666666666667
TF TF:M11420 Factor: ER81; motif: NACCGGAAGTN 0.00960373927505489 3210 13 8 0.615384615384615 0.00249221183800623
TF TF:M00912 Factor: C/EBP; motif: NTTRCNNAANNN 0.00960373927505489 4968 23 14 0.608695652173913 0.00281803542673108
TF TF:M04743 Factor: c-Myc; motif: NSCACGTGGN 0.00960373927505489 4819 26 15 0.576923076923077 0.00311267897904129
TF TF:M00483 Factor: ATF6; motif: TGACGTGG 0.0098284485635561 2627 12 7 0.583333333333333 0.00266463646745337
TF TF:M04690 Factor: C/EBPbeta; motif: RTTGCGCAA 0.00993601165648826 3915 22 12 0.545454545454545 0.00306513409961686
TF TF:M02055_1 Factor: ESE-1; motif: NSMGGAARTN; match class: 1 0.0102052760469471 2176 14 7 0.5 0.00321691176470588
TF TF:M01214_1 Factor: ESE-1; motif: NSMGGAARTN; match class: 1 0.0102052760469471 2176 14 7 0.5 0.00321691176470588
TF TF:M04714_1 Factor: Elf-1; motif: ACTTCCGGG; match class: 1 0.0103469094675238 2659 12 7 0.583333333333333 0.00263256863482512
TF TF:M08455 Factor: ERF:T-bet; motif: TMACACCGGAAR 0.0105471494696196 374 8 3 0.375 0.00802139037433155
TF TF:M09607_1 Factor: SAP-1; motif: ACCGGAAGTNN; match class: 1 0.0105471494696196 977 8 4 0.5 0.00409416581371546
TF TF:M09901 Factor: nerf; motif: NNNCCGGAAGTGN 0.0105471494696196 5352 29 17 0.586206896551724 0.00317638266068759
TF TF:M08345_1 Factor: HOXB2:PEA3; motif: ACCGGAAATGRN; match class: 1 0.0105471494696196 2198 14 7 0.5 0.00318471337579618
TF TF:M11448_1 Factor: Elf-1; motif: NANGCGGAAGTN; match class: 1 0.010688136035 2324 10 6 0.6 0.00258175559380379
TF TF:M11221_1 Factor: CREB1; motif: RTGACGYGTCAN; match class: 1 0.010688136035 5695 21 14 0.666666666666667 0.00245829675153644
TF TF:M11430_1 Factor: PEA3; motif: NACCGGAAGTN; match class: 1 0.0107941441655637 4902 12 9 0.75 0.0018359853121175
TF TF:M11439_1 Factor: Net; motif: NRCCGGAAGTN; match class: 1 0.0108333625524909 382 8 3 0.375 0.00785340314136126
TF TF:M00017_1 Factor: ATF; motif: CNSTGACGTNNNYC; match class: 1 0.0109410986811159 2222 14 7 0.5 0.00315031503150315
TF TF:M10887 Factor: PRX-2; motif: NNCRTTAN 0.011623409320903 5715 11 9 0.818181818181818 0.0015748031496063
TF TF:M10885 Factor: PRX-2; motif: NKCGTTAN 0.011623409320903 5715 11 9 0.818181818181818 0.0015748031496063
TF TF:M02059_1 Factor: ELK-1; motif: ACCGGAAGTN; match class: 1 0.011623409320903 3759 12 8 0.666666666666667 0.00212822559191274
TF TF:M11406 Factor: Pet-1; motif: NACCGGAAGTN 0.011623409320903 1301 29 8 0.275862068965517 0.00614911606456572
TF TF:M11382 Factor: ESE-1; motif: NWTRCGGAWGCN 0.011623409320903 10339 12 12 1 0.00116065383499371
TF TF:M03969 Factor: ELF5; motif: ANSMGGAAGTN 0.011623409320903 3339 29 13 0.448275862068966 0.00389338125187182
TF TF:M09608_1 Factor: Erg; motif: NNACCGGAARTSN; match class: 1 0.011623409320903 2389 10 6 0.6 0.00251151109250733
TF TF:M01861 Factor: ATF-1; motif: TNACGTCAN 0.011623409320903 6294 28 18 0.642857142857143 0.00285986653956149
TF TF:M08377_1 Factor: meis1:Elf-1; motif: NTGCCGGAAGTN; match class: 1 0.011623409320903 5051 14 10 0.714285714285714 0.00197980597901406
TF TF:M03967_1 Factor: ELF3; motif: WACCCGGAAGTAN; match class: 1 0.011623409320903 1972 8 5 0.625 0.00253549695740365
TF TF:M00799 Factor: Myc; motif: CACGTGS 0.0117873091357179 4988 26 15 0.576923076923077 0.00300721732157177
TF TF:M01163 Factor: Elk-1; motif: AACCGGAAGTR 0.0117873091357179 5260 18 12 0.666666666666667 0.00228136882129278
TF TF:M01145 Factor: c-Myc; motif: RACCACGTGCTC 0.0119301570528501 6248 24 16 0.666666666666667 0.00256081946222791
TF TF:M00981_1 Factor: CREB,; motif: NTGACGTNA; match class: 1 0.0119722173388414 2904 29 12 0.413793103448276 0.00413223140495868
TF TF:M09935_1 Factor: GABP-alpha; motif: NNNRCCGGAAGTGN; match class: 1 0.0121836258663981 1047 8 4 0.5 0.00382043935052531
TF TF:M11320_1 Factor: C/EBPdelta; motif: NRTTGCGYAAYN; match class: 1 0.0125957524044739 2586 28 11 0.392857142857143 0.00425367362722351
TF TF:M00117 Factor: C/EBPbeta; motif: NKNTTGCNYAAYNN 0.0126048330572911 4147 19 11 0.578947368421053 0.0026525198938992
TF TF:M02069_1 Factor: Erm; motif: ACCGGAAGTN; match class: 1 0.012880705392051 1955 12 6 0.5 0.0030690537084399
TF TF:M10727 Factor: HOXB8; motif: RTCRTTAN 0.012880705392051 6289 22 15 0.681818181818182 0.00238511687072667
TF TF:M03981 Factor: ETV3; motif: ACCGGAAGTN 0.012880705392051 2327 14 7 0.5 0.0030081650193382
TF TF:M11424_1 Factor: Erm; motif: NNSCGGAWGYN; match class: 1 0.012880705392051 2835 12 7 0.583333333333333 0.00246913580246914
TF TF:M01229 Factor: GTF2IRD1-isoform2; motif: GGGATTRNR 0.012880705392051 15179 29 29 1 0.0019105342907965
TF TF:M07209 Factor: ELK4; motif: NCRCTTCCGGN 0.012880705392051 1118 13 5 0.384615384615385 0.00447227191413238
TF TF:M03977 Factor: ETS1; motif: ACCGGAARYN 0.0129661633514651 10512 27 23 0.851851851851852 0.00218797564687976
TF TF:M08910_1 Factor: C/EBPBETA; motif: KRTTGCGYAAY; match class: 1 0.0129661633514651 3194 17 9 0.529411764705882 0.00281778334376957
TF TF:M11439 Factor: Net; motif: NRCCGGAAGTN 0.0129661633514651 2568 13 7 0.538461538461538 0.00272585669781931
TF TF:M11008_1 Factor: LHX4; motif: NTCRTTAN; match class: 1 0.0129661633514651 1626 19 7 0.368421052631579 0.0043050430504305
TF TF:M10578 Factor: Barhl-1; motif: NTAAACGN 0.0129661633514651 6099 29 18 0.620689655172414 0.0029513034923758
TF TF:M10999 Factor: LIM-1; motif: NNCGTTAN 0.0135007129570842 5894 11 9 0.818181818181818 0.00152697658635901
TF TF:M07483 Factor: CXXC1; motif: KNRNAMCGMWAAMNN 0.0135007129570842 1318 23 7 0.304347826086957 0.00531107738998483
TF TF:M10647 Factor: HMX2; motif: ACCACTTAAN 0.0137524558030631 1067 28 7 0.25 0.00656044985941893
TF TF:M02074 Factor: GABPalpha; motif: RCCGGAWRYN 0.0137524558030631 4607 13 9 0.692307692307692 0.00195354894725418
TF TF:M03969_1 Factor: ELF5; motif: ANSMGGAAGTN; match class: 1 0.0137524558030631 443 8 3 0.375 0.00677200902934537
TF TF:M09905_1 Factor: SAP-1; motif: NNCCGGAAGTGN; match class: 1 0.0139477093044194 2989 29 12 0.413793103448276 0.0040147206423553
TF TF:M00236 Factor: Arnt; motif: NDDNNCACGTGNNNNN 0.0139477093044194 2210 28 10 0.357142857142857 0.00452488687782805
TF TF:M03982_1 Factor: ETV4; motif: ACCGGAAGTN; match class: 1 0.0139477093044194 2009 12 6 0.5 0.00298656047784968
TF TF:M02012_1 Factor: HIF-1alpha; motif: NCACGT; match class: 1 0.0141106991009231 1770 18 7 0.388888888888889 0.00395480225988701
TF TF:M08759_1 Factor: c-Ets-2; motif: NCCGGAAGTG; match class: 1 0.0141265748809525 2915 12 7 0.583333333333333 0.00240137221269297
TF TF:M08759 Factor: c-Ets-2; motif: NCCGGAAGTG 0.0144095741727885 8319 25 19 0.76 0.00228392835677365
TF TF:M00738_1 Factor: E2F-4:DP-1; motif: TTTSGCGC; match class: 1 0.0144556710354835 3999 20 11 0.55 0.00275068767191798
TF TF:M08222_1 Factor: Elk-1:HOXB13; motif: ACCGGAAGTNGTAAAN; match class: 1 0.0144556710354835 2063 25 9 0.36 0.00436257876878332
TF TF:M08637 Factor: TEF-3:Erg; motif: ACCGGAAATRNNNNNCATWCC 0.0145466490888506 4382 24 13 0.541666666666667 0.0029666818804199
TF TF:M01181_1 Factor: Nkx3-2; motif: TRAGTG; match class: 1 0.014595983567472 3260 14 8 0.571428571428571 0.00245398773006135
TF TF:M01861_1 Factor: ATF-1; motif: TNACGTCAN; match class: 1 0.015062966140817 1896 22 8 0.363636363636364 0.00421940928270042
TF TF:M09605_1 Factor: Elf-1; motif: NAANCMGGAAGTGN; match class: 1 0.0151306815259002 1306 12 5 0.416666666666667 0.00382848392036753
TF TF:M11692 Factor: MEF-2C; motif: CCAWATWTRG 0.0151976654852194 1103 14 5 0.357142857142857 0.00453309156844968
TF TF:M10936 Factor: CHX10; motif: NTCRTTAN 0.0151976654852194 3019 9 6 0.666666666666667 0.00198741305067903
TF TF:M10945 Factor: VSX1; motif: NTCRTTAN 0.0151976654852194 3019 9 6 0.666666666666667 0.00198741305067903
TF TF:M10563 Factor: Msx-1; motif: NTCRTTAN 0.0151976654852194 3019 9 6 0.666666666666667 0.00198741305067903
TF TF:M10942 Factor: VSX1; motif: NTCRTTAN 0.0151976654852194 3019 9 6 0.666666666666667 0.00198741305067903
TF TF:M10747 Factor: GSH2; motif: NTCRTTAN 0.0151976654852194 3019 9 6 0.666666666666667 0.00198741305067903
TF TF:M09900_1 Factor: Elf-1; motif: NNANCCGGAAGTGS; match class: 1 0.0151976654852194 1158 8 4 0.5 0.00345423143350604
TF TF:M10956_1 Factor: isx; motif: NTCRTTAA; match class: 1 0.0151976654852194 3336 11 7 0.636363636363636 0.00209832134292566
TF TF:M10874 Factor: alx3; motif: NKCRTTAN 0.0151976654852194 3019 9 6 0.666666666666667 0.00198741305067903
TF TF:M10939 Factor: CHX10; motif: NTCRTTAN 0.0151976654852194 3019 9 6 0.666666666666667 0.00198741305067903
TF TF:M01876_1 Factor: GABP-beta; motif: ASMGGAAGKGN; match class: 1 0.0152840387595063 197 18 3 0.166666666666667 0.0152284263959391
TF TF:M10938 Factor: CHX10; motif: GCYAATTAY 0.01529837937379 328 25 4 0.16 0.0121951219512195
TF TF:M09876_1 Factor: DEC1; motif: NGCACGTGAS; match class: 1 0.0153789395122263 6252 29 18 0.620689655172414 0.00287907869481766
TF TF:M03972 Factor: ELK3; motif: ACCGGAAGTN 0.0154648601344427 1211 13 5 0.384615384615385 0.00412881915772089
TF TF:M10695 Factor: HOXA6; motif: RTCRTTAN 0.0155753862736312 6486 22 15 0.681818181818182 0.00231267345050879
TF TF:M11449 Factor: Elf-1; motif: NANCCGGAAGTN 0.0157601151523686 4305 14 9 0.642857142857143 0.00209059233449477
TF TF:M11452 Factor: Elf-1; motif: NANGCGGAAGTR 0.0159090269466901 6276 29 18 0.620689655172414 0.00286806883365201
TF TF:M10628 Factor: NKX3A; motif: NTCGTTAN 0.0159344831955702 4543 21 12 0.571428571428571 0.00264142637023993
TF TF:M09812_1 Factor: MYC; motif: NNCCACGTGCNN; match class: 1 0.0161635693934979 5242 26 15 0.576923076923077 0.00286150324303701
TF TF:M10074 Factor: Spi-B; motif: NRAAAGAGGAAGTGARA 0.0163817263213428 1611 26 8 0.307692307692308 0.00496585971446307
TF TF:M11882_1 Factor: pax-6; motif: NYACGCNYSANYGMNCN; match class: 1 0.0164304746643402 11423 26 23 0.884615384615385 0.00201348157226648
TF TF:M09901_1 Factor: nerf; motif: NNNCCGGAAGTGN; match class: 1 0.016702323964796 1363 12 5 0.416666666666667 0.00366837857666911
TF TF:M10600 Factor: Dlx-7; motif: NTCRTTAN 0.016892407535952 7477 20 15 0.75 0.00200615220008025
TF TF:M11428_1 Factor: PEA3; motif: NACCGGAAGTN; match class: 1 0.0171550539609497 2146 12 6 0.5 0.00279589934762349
TF TF:M00050_1 Factor: E2F; motif: TTTSGCGC; match class: 1 0.0172569842349942 1875 18 7 0.388888888888889 0.00373333333333333
TF TF:M11437 Factor: SAP-1; motif: NRCCGGAWGYN 0.0175250631622316 2788 13 7 0.538461538461538 0.00251076040172166
TF TF:M09887 Factor: CREB1; motif: NRRTGACGTMA 0.018037593388118 5419 28 16 0.571428571428571 0.00295257427569662
TF TF:M08423_1 Factor: TEF-3:ER81; motif: ACCGGAAATRCC; match class: 1 0.018098839169606 654 14 4 0.285714285714286 0.00611620795107034
TF TF:M01165_1 Factor: Elk-1; motif: RACCGGAAGTR; match class: 1 0.0183663693409209 2185 12 6 0.5 0.00274599542334096
TF TF:M09600_1 Factor: CREB1; motif: TKACGTCAYNN; match class: 1 0.0184219791938348 1552 16 6 0.375 0.0038659793814433
TF TF:M02061 Factor: ERF; motif: ACCGGAARYN 0.0186317446904445 2579 14 7 0.5 0.00271423032183017
TF TF:M08917 Factor: GABP-ALPHA; motif: RCCGGAARTNN 0.0190988597165375 2702 29 11 0.379310344827586 0.00407105847520355
TF TF:M07056 Factor: Pitx2; motif: WNTAAWCCCA 0.0190988597165375 4685 29 15 0.517241379310345 0.0032017075773746
TF TF:M02011 Factor: HES-1; motif: GSCACGMGMC 0.0190988597165375 4259 12 8 0.666666666666667 0.00187837520544729
TF TF:M08482 Factor: FOXO1A:HOXA10; motif: RWMAACANCRTWAA 0.0190988597165375 4206 20 11 0.55 0.00261531145981931
TF TF:M00981 Factor: CREB,; motif: NTGACGTNA 0.0190988597165375 8345 29 21 0.724137931034483 0.00251647693229479
TF TF:M02114 Factor: pitx2; motif: NNTAAWCCCA 0.0190988597165375 4685 29 15 0.517241379310345 0.0032017075773746
TF TF:M04744_1 Factor: ATF-3; motif: GGCGCSSNSNGRTSACGTSA; match class: 1 0.0190988597165375 4889 28 15 0.535714285714286 0.00306811208836163
TF TF:M12350 Factor: zbtb2; motif: NTTTCCGGTAAN 0.0191038261164926 418 10 3 0.3 0.00717703349282297
TF TF:M11320 Factor: C/EBPdelta; motif: NRTTGCGYAAYN 0.0192778097632288 5477 28 16 0.571428571428571 0.00292130728501004
TF TF:M11290_1 Factor: ATF-3; motif: NATGATGTCATN; match class: 1 0.019367335346367 1872 6 4 0.666666666666667 0.00213675213675214
TF TF:M08539 Factor: ERF:HOXA3; motif: ACCGGAARYNNNNNNMATTA 0.0193956931309638 167 24 3 0.125 0.0179640718562874
TF TF:M09913 Factor: ER81; motif: NNCCGGAAGYG 0.0193956931309638 2871 13 7 0.538461538461538 0.00243817485196796
TF TF:M00178 Factor: CREB; motif: NSTGACGTMANN 0.0193956931309638 5255 29 16 0.551724137931034 0.00304471931493815
TF TF:M10643_1 Factor: Homeobox; motif: NCAMTTANC; match class: 1 0.0193956931309638 486 19 4 0.210526315789474 0.00823045267489712
TF TF:M11435_1 Factor: Elk-1; motif: NNCCGGAAGTN; match class: 1 0.0193956931309638 5745 27 16 0.592592592592593 0.00278503046127067
TF TF:M03987 Factor: FEV; motif: ACCGGAAGTN 0.0197392772277859 1318 13 5 0.384615384615385 0.00379362670713202
TF TF:M11450_1 Factor: Elf-1; motif: NANSCGGAAGTR; match class: 1 0.020140369752394 1315 8 4 0.5 0.00304182509505703
TF TF:M11433_1 Factor: Elk-1; motif: NRCCGGAAGTN; match class: 1 0.0203911346055965 2261 12 6 0.5 0.00265369305616984
TF TF:M10593 Factor: Dlx-6; motif: NTCRTTAN 0.0203911346055965 7158 21 15 0.714285714285714 0.00209555741827326
TF TF:M00428_1 Factor: E2F-1; motif: NKTSSCGC; match class: 1 0.0204905011082207 3615 11 7 0.636363636363636 0.00193637621023513
TF TF:M04691_1 Factor: Kaiso; motif: TCTCGCGAG; match class: 1 0.0206133830611286 10488 22 19 0.863636363636364 0.00181159420289855
TF TF:M09887_1 Factor: CREB1; motif: NRRTGACGTMA; match class: 1 0.0208622162767828 1616 16 6 0.375 0.00371287128712871
TF TF:M07601 Factor: C-Myc; motif: NGCCACGTGNN 0.0209152853079364 5882 29 17 0.586206896551724 0.00289017341040462
TF TF:M00039_1 Factor: CREB; motif: TGACGTMA; match class: 1 0.0210166086473147 1482 12 5 0.416666666666667 0.00337381916329285
TF TF:M11015_1 Factor: ISL2; motif: SCACTTAN; match class: 1 0.0210166086473147 579 28 5 0.178571428571429 0.00863557858376511
TF TF:M00466 Factor: HIF1; motif: NGTACGTGCNGB 0.0210166086473147 2997 27 11 0.407407407407407 0.00367033700367034
TF TF:M11419 Factor: ER81; motif: NNCCGGAWGYN 0.0210166086473147 5699 14 10 0.714285714285714 0.00175469380593087
TF TF:M08632 Factor: TEF-3:Dlx-2; motif: RMATWCYNNNYAATTA 0.0210166086473147 600 27 5 0.185185185185185 0.00833333333333333
TF TF:M10877 Factor: alx3; motif: NNCRTTAN 0.0210909565813098 4165 10 7 0.7 0.00168067226890756
TF TF:M01896 Factor: C/EBPbeta; motif: TKNNGCAANN 0.0216448609392558 4512 22 12 0.545454545454545 0.00265957446808511
TF TF:M09975 Factor: LEF-1; motif: NCCTTTSWNNTNYN 0.0216448609392558 3959 8 6 0.75 0.0015155342258146
TF TF:M08982_1 Factor: YY1; motif: NAANATGGCGNNN; match class: 1 0.0221742865748125 1662 27 8 0.296296296296296 0.00481347773766546
TF TF:M08950_1 Factor: MAX; motif: CACGTG; match class: 1 0.0224735255614386 5942 29 17 0.586206896551724 0.00286098956580276
TF TF:M11413 Factor: ER71; motif: NACCGGAARTN 0.0224735255614386 2111 13 6 0.461538461538462 0.00284225485551871
TF TF:M08950 Factor: MAX; motif: CACGTG 0.0224735255614386 5942 29 17 0.586206896551724 0.00286098956580276
TF TF:M00726 Factor: USF2; motif: CASGYG 0.0224735255614386 5942 29 17 0.586206896551724 0.00286098956580276
TF TF:M00726_1 Factor: USF2; motif: CASGYG; match class: 1 0.0224735255614386 5942 29 17 0.586206896551724 0.00286098956580276
TF TF:M09608 Factor: Erg; motif: NNACCGGAARTSN 0.0226567660531551 8152 16 13 0.8125 0.00159470068694799
TF TF:M09812 Factor: MYC; motif: NNCCACGTGCNN 0.0228764775097897 5507 26 15 0.576923076923077 0.00272380606500817
TF TF:M11432_1 Factor: Elk-1; motif: NACMGGAAGTN; match class: 1 0.0228764775097897 1525 12 5 0.416666666666667 0.00327868852459016
TF TF:M04485_1 Factor: RARG; motif: RAGGTCAASYARAGGTCA; match class: 1 0.0230589938807798 838 6 3 0.5 0.0035799522673031
TF TF:M00217 Factor: USF; motif: NCACGTGN 0.0234158659708362 4108 24 12 0.5 0.00292112950340798
TF TF:M10612 Factor: Dlx-5; motif: NTCRTTAN 0.0234158659708362 8225 21 16 0.761904761904762 0.00194528875379939
TF TF:M10603 Factor: Dlx-7; motif: NTCRTTAN 0.0234158659708362 8225 21 16 0.761904761904762 0.00194528875379939
TF TF:M09880 Factor: C/EBPalpha; motif: NRTTGTGCAAYN 0.0234540287971839 3426 28 12 0.428571428571429 0.00350262697022767
TF TF:M10625 Factor: Nkx3-2; motif: NTCGTTAN 0.0237794069793304 6062 22 14 0.636363636363636 0.0023094688221709
TF TF:M11454 Factor: ELFR; motif: NANGMGGAAGTN 0.0238287948811684 1072 24 6 0.25 0.00559701492537313
TF TF:M01185 Factor: BCL-6; motif: WRCTTTCKAGGRAT 0.0241588537495812 6054 8 7 0.875 0.00115626032375289
TF TF:M10858 Factor: En-2; motif: NTCRTTARN 0.0241588537495812 9165 12 11 0.916666666666667 0.00120021822149482
TF TF:M10575 Factor: Gbx2; motif: NTCRTTAN 0.0247449559016962 2224 9 5 0.555555555555556 0.00224820143884892
TF TF:M11457 Factor: nerf; motif: NANGCGGAAGTR 0.0247449559016962 1082 24 6 0.25 0.0055452865064695
TF TF:M03985 Factor: ETV6; motif: NSCGGAAGTR 0.0248501724565733 1136 23 6 0.260869565217391 0.00528169014084507
TF TF:M08575 Factor: GCMa:C/EBPbeta; motif: ATGCGGGTNNRTTGCGCAAY 0.0248501724565733 7026 9 8 0.888888888888889 0.00113862795331625
TF TF:M07415 Factor: Elf-1; motif: AWCCCGGAAGTN 0.0248501724565733 7978 27 19 0.703703703703704 0.00238154926046628
TF TF:M10686 Factor: HOXB7; motif: GTCRTTAN 0.0248501724565733 3712 20 10 0.5 0.00269396551724138
TF TF:M02054 Factor: ELF2; motif: CCCGGAARYN 0.0248501724565733 3066 13 7 0.538461538461538 0.00228310502283105
TF TF:M00055 Factor: N-Myc; motif: NNCCACGTGNNN 0.0248501724565733 4167 24 12 0.5 0.00287976961843053
TF TF:M08313_1 Factor: GCMa:PEA3; motif: ATRCGGGCGGAAGTR; match class: 1 0.0248801732335671 9721 25 20 0.8 0.0020574015019031
TF TF:M02064_1 Factor: c-ets-2; motif: ACCGGAWRTN; match class: 1 0.0259094414901193 4592 12 8 0.666666666666667 0.00174216027874564
TF TF:M01798 Factor: RPC155; motif: TCMNGRGTTCRAGWCC 0.026267382290368 975 27 6 0.222222222222222 0.00615384615384615
TF TF:M11427_1 Factor: PEA3; motif: NACCGGAAGTN; match class: 1 0.026267382290368 4606 12 8 0.666666666666667 0.00173686495874946
TF TF:M00615 Factor: c-Myc:Max; motif: NNNNNNNCACGTGNNNNNNN 0.026267382290368 6679 29 18 0.620689655172414 0.00269501422368618
TF TF:M00615_1 Factor: c-Myc:Max; motif: NNNNNNNCACGTGNNNNNNN; match class: 1 0.026267382290368 6679 29 18 0.620689655172414 0.00269501422368618
TF TF:M11535 Factor: E2F-4; motif: TTTTGGCGCCAWWN 0.0264500767957107 10884 29 24 0.827586206896552 0.00220507166482911
TF TF:M02054_1 Factor: ELF2; motif: CCCGGAARYN; match class: 1 0.0264500767957107 456 11 3 0.272727272727273 0.00657894736842105
TF TF:M12208 Factor: GATA-6; motif: WGATAACGATCW 0.0264500767957107 4281 18 10 0.555555555555556 0.00233590282644242
TF TF:M11530 Factor: E2F-2; motif: NWTTTGGCGCCAWWNN 0.026549374099225 14593 29 28 0.96551724137931 0.00191872815733571
TF TF:M03820 Factor: ER-alpha; motif: GGNNNNNNTGACCYN 0.026549374099225 2765 26 10 0.384615384615385 0.00361663652802893
TF TF:M02064 Factor: c-ets-2; motif: ACCGGAWRTN 0.0277129259358025 10939 15 14 0.933333333333333 0.001279824481214
TF TF:M07140_1 Factor: Kaiso; motif: NTCTCGCGAGANYTN; match class: 1 0.028117695026844 189 26 3 0.115384615384615 0.0158730158730159
TF TF:M07386 Factor: Lmx1; motif: RDNTAATT 0.028223522622257 6123 29 17 0.586206896551724 0.00277641678915564
TF TF:M12165_1 Factor: BTEB2; motif: NCCACRCCCN; match class: 1 0.0282708698791431 940 6 3 0.5 0.00319148936170213
TF TF:M00119_1 Factor: Max; motif: NNANCACGTGNTNN; match class: 1 0.0286869058288773 6746 29 18 0.620689655172414 0.00266824785057812
TF TF:M11450 Factor: Elf-1; motif: NANSCGGAAGTR 0.0286869058288773 5601 17 11 0.647058823529412 0.00196393501160507
TF TF:M00119 Factor: Max; motif: NNANCACGTGNTNN 0.0286869058288773 6746 29 18 0.620689655172414 0.00266824785057812
TF TF:M11075_1 Factor: Sohlh2; motif: NNCACGTGNN; match class: 1 0.0288691347453477 8043 29 20 0.689655172413793 0.00248663434042024
TF TF:M08423 Factor: TEF-3:ER81; motif: ACCGGAAATRCC 0.0289047838064957 3845 14 8 0.571428571428571 0.00208062418725618
TF TF:M10861 Factor: En-1; motif: VTCRTTAN 0.0289089207632945 3653 9 6 0.666666666666667 0.00164248562825075
TF TF:M08930_1 Factor: JUND:FRA-1; motif: RTGACGTMAY; match class: 1 0.0289089207632945 1607 4 3 0.75 0.00186683260734287
TF TF:M11325 Factor: C/EBPgamma; motif: NNTTGCGYAANN 0.0301323436848646 2708 27 10 0.37037037037037 0.00369276218611521
TF TF:M08282 Factor: Fli-1:Prrxl1; motif: ACCGGAAGTAATTAN 0.0304884924849639 2188 18 7 0.388888888888889 0.00319926873857404
TF TF:M10560 Factor: Msx-2; motif: NTCRTTAN 0.0307365538261251 4570 10 7 0.7 0.00153172866520788
TF TF:M10589 Factor: BSX; motif: NTCRTTAN 0.0307365538261251 4570 10 7 0.7 0.00153172866520788
TF TF:M09607 Factor: SAP-1; motif: ACCGGAAGTNN 0.0314269204196154 4727 25 13 0.52 0.00275015866299979
TF TF:M10027 Factor: Pax-5; motif: SCNNGGGCARCNRAGCGWGAC 0.0314269204196154 3374 26 11 0.423076923076923 0.0032602252519265
TF TF:M09606_1 Factor: nerf; motif: NRRNSCGGAAGNRNNNN; match class: 1 0.0315485921507587 1704 12 5 0.416666666666667 0.00293427230046948
TF TF:M11421 Factor: ER81; motif: NACCGGAAGTN 0.0315873310123951 2341 13 6 0.461538461538462 0.00256300726185391
TF TF:M07037 Factor: C/EBPalpha; motif: NNNNNTTKCNNAAN 0.0318926982843734 3386 7 5 0.714285714285714 0.00147666863555818
TF TF:M10692 Factor: HOXB6; motif: GTCGTTAN 0.0324438891184736 5380 9 7 0.777777777777778 0.00130111524163569
TF TF:M08306_1 Factor: GCMa:Elf-1; motif: NNCGGAARTGCKGGT; match class: 1 0.0325133459375662 231 23 3 0.130434782608696 0.012987012987013
TF TF:M08557 Factor: ER71:HOXA2; motif: RCCGGAAGNNNNNNNMATTA 0.0325133459375662 221 24 3 0.125 0.0135746606334842
TF TF:M11389 Factor: elf5; motif: GAMCCGGAAGTN 0.0325198732638658 1308 29 7 0.241379310344828 0.00535168195718654
TF TF:M08771 Factor: HOXA4; motif: RYCATTRN 0.0325198732638658 2900 18 8 0.444444444444444 0.00275862068965517
TF TF:M00740_1 Factor: Rb:E2F-1:DP-1; motif: TTTSGCGC; match class: 1 0.0325767026058395 4583 23 12 0.521739130434783 0.0026183722452542
TF TF:M11323 Factor: C/EBPgamma; motif: NRTTGCGYAANN 0.0325767026058395 1237 23 6 0.260869565217391 0.00485044462409054
TF TF:M00916 Factor: CREB; motif: NNTKACGTCANNNS 0.0325767026058395 5889 28 16 0.571428571428571 0.00271692986924775
TF TF:M08213_1 Factor: Elk-1:TBR2; motif: TNRCACCGGAAGN; match class: 1 0.0333642247235516 1417 9 4 0.444444444444444 0.00282286520818631
TF TF:M08266_1 Factor: ER71:Pax-5; motif: ACCGGAACYACGCWTSANTG; match class: 1 0.0333642247235516 8979 27 20 0.740740740740741 0.00222741953446932
TF TF:M11066_1 Factor: HES-7; motif: GNCACGYGNN; match class: 1 0.0335681225179315 8172 29 20 0.689655172413793 0.00244738130200685
TF TF:M02072 Factor: Pet-1; motif: ACCGGAWRTN 0.0340052892413815 2395 13 6 0.461538461538462 0.00250521920668058
TF TF:M11321_1 Factor: C/EBPdelta; motif: NRTTGCGYAAYN; match class: 1 0.034301524720762 1852 27 8 0.296296296296296 0.00431965442764579
TF TF:M09725 Factor: DREF; motif: CTYYCWCTTCCY 0.0349368478061224 7519 9 8 0.888888888888889 0.00106397127277564
TF TF:M09866 Factor: ATF-1; motif: NNRTGACGYMA 0.0349368478061224 3162 28 11 0.392857142857143 0.00347881087919039
TF TF:M10073 Factor: PU.1; motif: NRAAAGAGGAAGTGRNN 0.0352501971803977 2416 26 9 0.346153846153846 0.00372516556291391
TF TF:M01876 Factor: GABP-beta; motif: ASMGGAAGKGN 0.0352501971803977 2138 29 9 0.310344827586207 0.00420954162768943
TF TF:M00017 Factor: ATF; motif: CNSTGACGTNNNYC 0.0352501971803977 7226 28 18 0.642857142857143 0.00249100470523111
TF TF:M00144 Factor: Pax-5; motif: RRMSWGANWYCTNRAGCGKRACSRYNSM 0.0354986150129419 13205 26 24 0.923076923076923 0.00181749337372207
TF TF:M08295_1 Factor: FOXO1A:Elf-1; motif: NAGAAAACCGAANM; match class: 1 0.0360922460005237 4997 27 14 0.518518518518518 0.00280168100860516
TF TF:M11005_1 Factor: LHX4; motif: NNCRTTAN; match class: 1 0.0371545669727727 4203 11 7 0.636363636363636 0.00166547704020937
TF TF:M00797 Factor: HIF1; motif: GNNKACGTGCGGNN 0.037301577811646 3576 22 10 0.454545454545455 0.00279642058165548
TF TF:M10991 Factor: lmx1b; motif: CTCGTTAA 0.0374463867892926 1589 19 6 0.315789473684211 0.00377595972309629
TF TF:M10704 Factor: HoxA5; motif: RTCATTAN 0.0379072940467988 5447 18 11 0.611111111111111 0.00201946025335047
TF TF:M00118 Factor: c-Myc:Max; motif: NNACCACGTGGTNN 0.0382202621273702 6977 29 18 0.620689655172414 0.00257990540346854
TF TF:M11696 Factor: MEF-2B1; motif: CCNWATWWRG 0.0382202621273702 2268 14 6 0.428571428571429 0.00264550264550265
TF TF:M00118_1 Factor: c-Myc:Max; motif: NNACCACGTGGTNN; match class: 1 0.0382202621273702 6977 29 18 0.620689655172414 0.00257990540346854
TF TF:M00678 Factor: Tel-2; motif: YTACTTCCTG 0.039330549425468 5292 26 14 0.538461538461538 0.00264550264550265
TF TF:M00187 Factor: USF; motif: GYCACGTGNC 0.039527179812402 3775 15 8 0.533333333333333 0.00211920529801325
TF TF:M11316_1 Factor: C/EBPbeta; motif: NRTTGCGYAAYN; match class: 1 0.0397131834519056 2743 28 10 0.357142857142857 0.00364564345607
TF TF:M01863 Factor: ATF-3; motif: RTKRCGTCANN 0.0400160601284365 1885 4 3 0.75 0.00159151193633952
TF TF:M00177 Factor: CREB; motif: NSTGACGTAANN 0.0401071715935283 5221 29 15 0.517241379310345 0.00287301283279065
TF TF:M03812 Factor: arnt; motif: CACGYA 0.0401509829631271 4330 19 10 0.526315789473684 0.0023094688221709
TF TF:M00039 Factor: CREB; motif: TGACGTMA 0.0402251388382251 5222 14 9 0.642857142857143 0.00172347759479127
TF TF:M00716_1 Factor: ZF5; motif: GSGCGCGR; match class: 1 0.0405968876692721 14106 17 17 1 0.00120516092442932
TF TF:M12275 Factor: YY1; motif: NGCCGCCATYTTGN 0.0412683415550963 7043 29 18 0.620689655172414 0.00255572909271617
TF TF:M08418_1 Factor: TEF-3:Elk-1; motif: RMATWCCGGAWGT; match class: 1 0.0412683415550963 5247 14 9 0.642857142857143 0.00171526586620926
TF TF:M11002 Factor: LHX5; motif: NTCGTTAN 0.0412683415550963 1638 19 6 0.315789473684211 0.00366300366300366
TF TF:M11008 Factor: LHX4; motif: NTCRTTAN 0.0413376079094332 6586 10 8 0.8 0.00121469784391133
TF TF:M03571 Factor: C/EBPdelta; motif: TTGCNNMAN 0.0417554678175895 3711 7 5 0.714285714285714 0.00134734572891404
TF TF:M09966_1 Factor: Kaiso; motif: SARNYCTCGCGAGAN; match class: 1 0.0417554678175895 449 28 4 0.142857142857143 0.0089086859688196
TF TF:M10438 Factor: ZF5; motif: GGSGCGCGS 0.0417554678175895 16228 29 29 1 0.00178703475474489
TF TF:M08767_1 Factor: HES-1; motif: GNCACGTGNC; match class: 1 0.0421516134558669 7709 29 19 0.655172413793103 0.00246465170579842
TF TF:M04897 Factor: Fra-1; motif: ACTCATG 0.0430419096299992 2560 17 7 0.411764705882353 0.002734375
TF TF:M07380 Factor: E2F-4; motif: NTTTCSCGCC 0.0430544500019283 13022 29 26 0.896551724137931 0.00199662110274919
TF TF:M10698 Factor: HOXB5; motif: RTCRTTAN 0.0433998528203019 4697 18 10 0.555555555555556 0.00212901852246115
TF TF:M10609 Factor: Dlx-3; motif: NTCRTTAN 0.0433998528203019 4697 18 10 0.555555555555556 0.00212901852246115
TF TF:M08231_1 Factor: Elk-1:T-bet; motif: TCACACCGGAAGNN; match class: 1 0.0436437703475648 1581 9 4 0.444444444444444 0.00253004427577483
TF TF:M02012 Factor: HIF-1alpha; motif: NCACGT 0.0455079026167895 6648 22 14 0.636363636363636 0.00210589651022864
TF TF:M10755 Factor: hoxd1; motif: NTCRTTAN 0.0462642919748977 2948 19 8 0.421052631578947 0.00271370420624152
TF TF:M11012 Factor: islet1; motif: SCAMTTAN 0.0469545998058675 6170 28 16 0.571428571428571 0.00259319286871961
TF TF:M00333 Factor: ZF5; motif: NRNGNGCGCGCWN 0.0469545998058675 15072 29 28 0.96551724137931 0.00185774946921444
TF TF:M04352 Factor: HOXC10; motif: GTCRTAAAAN 0.0474245852094972 769 9 3 0.333333333333333 0.00390117035110533
TF TF:M04287 Factor: BARHL2; motif: NNTAAAYGNN 0.0474245852094972 4416 28 13 0.464285714285714 0.00294384057971014
TF TF:M08874 Factor: E2F1; motif: NNNNNGCGSSAAAN 0.0474245852094972 7201 15 11 0.733333333333333 0.00152756561588668
TF TF:M01154 Factor: c-Myc; motif: KACCACGTGSYY 0.0480476826628578 5313 24 13 0.541666666666667 0.00244682853378506
TF TF:M07034_1 Factor: ATF-1; motif: NNNTGACGTNNN; match class: 1 0.0480476826628578 1179 12 4 0.333333333333333 0.00339270568278202
TF TF:M08767 Factor: HES-1; motif: GNCACGTGNC 0.0480476826628578 7813 29 19 0.655172413793103 0.00243184436196083
TF TF:M03839 Factor: Pax-2; motif: CAYSCCTSAGT 0.0483042260630537 5052 4 4 1 0.000791765637371338
TF TF:M00421 Factor: MEIS1B:HOXA9; motif: TGACASTTTWAYRR 0.0484641370080198 6675 12 9 0.75 0.00134831460674157
TF TF:M08377 Factor: meis1:Elf-1; motif: NTGCCGGAAGTN 0.0485798752514643 11275 25 21 0.84 0.00186252771618625
TF TF:M07234_1 Factor: YY1; motif: CAARATGGCNGC; match class: 1 0.0494782868330306 1177 27 6 0.222222222222222 0.00509770603228547
TF TF:M12035_1 Factor: Tbx1; motif: NNAGGTGTGAAN; match class: 1 0.049629598846879 319 21 3 0.142857142857143 0.00940438871473354
TF TF:M07335 Factor: Six-1; motif: CTCAGVTTTCT 0.0498653877833181 1010 14 4 0.285714285714286 0.00396039603960396
TF TF:M08786_1 Factor: Tbx3; motif: AGGTGTNR; match class: 1 0.0498653877833181 466 29 4 0.137931034482759 0.00858369098712446
TF TF:M10723 Factor: HOXD8; motif: RTCRTTAN 0.0498653877833181 4249 9 6 0.666666666666667 0.00141209696399153
TF TF:M10797_1 Factor: HOXA10; motif: RGTCGTAAAAN; match class: 1 0.0498653877833181 1128 20 5 0.25 0.00443262411347518
WP WP:WP477 Cytoplasmic Ribosomal Proteins 5.54276988970519e-51 90 29 27 0.931034482758621 0.3

pEpi19 transcription factor target enrichment of top program genes

TF enrichment of pEpi19
Possible regulators of activation of pEpi19 in epithelial cells. (Left) pearson correlation of TF expression and gene expression program activatity in Epithelial cells, (right) negative log p-value for enrichment of TF binding sites among top uniqueness weighted genes for the gene program. Blue bars indicate significant TFs meeting the following criteria: FDR<0.1, overlap > 2, Corr. R > 0, permutation based p-value < 0.05.