pTNI15 program activity among T/NK/ILC cells

Activation of pTNI15
pTNI15 gene program activation in T/NK/ILC cells.
Gene program activation of pTNI15 by different cell subtypes
pTNI15 gene program activation among cells of different subtypes (T/NK/ILC cells).

pTNI15 top program genes

Top genes of pTNI15 program
Bar plots showing the top genes for each gene program, ranked by (left) unique weights, (right) raw weights.

pTNI15 gene-set enrichment of top program genes (using g-profiler)

GSEA wth gene profiler of pTNI15
pTNI15 gene-set enrichment summary using g-profiler webtool.
Source termID Name Padj Tsize Qsize Overlap Precision Recall
GO:BP GO:0006457 protein folding 4.50605655749673e-19 225 40 17 0.425 0.0755555555555556
GO:BP GO:0006986 response to unfolded protein 1.43753922704532e-17 184 30 14 0.466666666666667 0.0760869565217391
GO:BP GO:0035966 response to topologically incorrect protein 3.38206716804544e-17 205 30 14 0.466666666666667 0.0682926829268293
GO:BP GO:0006458 'de novo' protein folding 3.38206716804544e-17 40 19 9 0.473684210526316 0.225
GO:BP GO:0009408 response to heat 1.21261933114635e-16 159 31 13 0.419354838709677 0.0817610062893082
GO:BP GO:0051085 chaperone cofactor-dependent protein refolding 1.03369060157444e-15 31 19 8 0.421052631578947 0.258064516129032
GO:BP GO:0061077 chaperone-mediated protein folding 1.16730871868404e-15 61 19 9 0.473684210526316 0.147540983606557
GO:BP GO:0051084 'de novo' posttranslational protein folding 2.96581990197436e-15 36 19 8 0.421052631578947 0.222222222222222
GO:BP GO:0009266 response to temperature stimulus 7.99881060903884e-15 228 31 13 0.419354838709677 0.0570175438596491
GO:BP GO:0042026 protein refolding 4.48573191010852e-14 23 20 7 0.35 0.304347826086957
GO:BP GO:0034605 cellular response to heat 1.01327731449828e-12 118 31 10 0.32258064516129 0.0847457627118644
GO:BP GO:0009628 response to abiotic stimulus 1.13015453131511e-11 1261 20 15 0.75 0.0118953211736717
GO:BP GO:1900034 regulation of cellular response to heat 3.66760000585461e-11 79 8 6 0.75 0.0759493670886076
GO:BP GO:0050790 regulation of catalytic activity 8.30223983102609e-11 2545 62 33 0.532258064516129 0.0129666011787819
GO:BP GO:0010033 response to organic substance 2.54330487681178e-10 3412 19 18 0.947368421052632 0.00527549824150059
GO:BP GO:0065009 regulation of molecular function 2.54330487681178e-10 3221 62 36 0.580645161290323 0.0111766532132878
GO:BP GO:0033554 cellular response to stress 1.39135007225806e-09 2111 16 14 0.875 0.00663192799621033
GO:BP GO:0042221 response to chemical 1.66534375307182e-09 4781 19 19 1 0.00397406400334658
GO:BP GO:0090084 negative regulation of inclusion body assembly 6.19936776261618e-09 11 123 6 0.0487804878048781 0.545454545454545
GO:BP GO:0070841 inclusion body assembly 2.66350224163918e-08 24 123 7 0.0569105691056911 0.291666666666667
GO:BP GO:0090083 regulation of inclusion body assembly 9.89159564317188e-08 17 3 3 1 0.176470588235294
GO:BP GO:0043065 positive regulation of apoptotic process 1.75256880647461e-07 604 115 20 0.173913043478261 0.033112582781457
GO:BP GO:0043068 positive regulation of programmed cell death 2.70021537789123e-07 621 115 20 0.173913043478261 0.0322061191626409
GO:BP GO:0043085 positive regulation of catalytic activity 2.78525120402536e-07 1418 40 17 0.425 0.0119887165021157
GO:BP GO:0042981 regulation of apoptotic process 2.81879561723149e-07 1549 61 22 0.360655737704918 0.0142027114267269
GO:BP GO:0010941 regulation of cell death 2.82759761899731e-07 1720 56 22 0.392857142857143 0.0127906976744186
GO:BP GO:0080135 regulation of cellular response to stress 2.82759761899731e-07 725 33 12 0.363636363636364 0.016551724137931
GO:BP GO:0097201 negative regulation of transcription from RNA polymerase II promoter in response to stress 3.23822714338043e-07 12 30 4 0.133333333333333 0.333333333333333
GO:BP GO:0006950 response to stress 3.4659058279558e-07 4170 16 15 0.9375 0.00359712230215827
GO:BP GO:0043067 regulation of programmed cell death 3.47658447432618e-07 1582 56 21 0.375 0.0132743362831858
GO:BP GO:0016032 viral process 4.02099603742863e-07 942 18 10 0.555555555555556 0.0106157112526539
GO:BP GO:0051338 regulation of transferase activity 5.78987866391481e-07 1035 62 18 0.290322580645161 0.0173913043478261
GO:BP GO:0044093 positive regulation of molecular function 6.2763599588271e-07 1771 21 13 0.619047619047619 0.00734048560135517
GO:BP GO:0044403 biological process involved in symbiotic interaction 6.58411883426529e-07 1001 18 10 0.555555555555556 0.00999000999000999
GO:BP GO:0010942 positive regulation of cell death 9.12483103310613e-07 684 115 20 0.173913043478261 0.0292397660818713
GO:BP GO:0043618 regulation of transcription from RNA polymerase II promoter in response to stress 2.04426949447417e-06 111 30 6 0.2 0.0540540540540541
GO:BP GO:0043620 regulation of DNA-templated transcription in response to stress 2.72870880785359e-06 117 30 6 0.2 0.0512820512820513
GO:BP GO:0070423 nucleotide-binding oligomerization domain containing signaling pathway 2.85800164726169e-06 40 16 4 0.25 0.1
GO:BP GO:0006915 apoptotic process 2.85800164726169e-06 1990 56 22 0.392857142857143 0.0110552763819095
GO:BP GO:0035872 nucleotide-binding domain, leucine rich repeat containing receptor signaling pathway 3.04783912700156e-06 41 16 4 0.25 0.0975609756097561
GO:BP GO:0034097 response to cytokine 3.80151419214673e-06 1226 18 10 0.555555555555556 0.00815660685154975
GO:BP GO:0080134 regulation of response to stress 4.41456338350399e-06 1443 13 9 0.692307692307692 0.00623700623700624
GO:BP GO:0034620 cellular response to unfolded protein 4.41456338350399e-06 149 14 5 0.357142857142857 0.0335570469798658
GO:BP GO:0032268 regulation of cellular protein metabolic process 4.60807996544737e-06 2541 62 26 0.419354838709677 0.0102321920503739
GO:BP GO:0070887 cellular response to chemical stimulus 5.53369317146649e-06 3393 18 14 0.777777777777778 0.00412614205717654
GO:BP GO:0008219 cell death 5.65963370620406e-06 2292 56 23 0.410714285714286 0.0100349040139616
GO:BP GO:0071310 cellular response to organic substance 5.8291335164164e-06 2776 18 13 0.722222222222222 0.00468299711815562
GO:BP GO:0031396 regulation of protein ubiquitination 6.22583606053333e-06 211 21 6 0.285714285714286 0.028436018957346
GO:BP GO:0035967 cellular response to topologically incorrect protein 6.65242316929237e-06 168 14 5 0.357142857142857 0.0297619047619048
GO:BP GO:0048583 regulation of response to stimulus 6.65242316929237e-06 4278 16 14 0.875 0.00327255726975222
GO:BP GO:0012501 programmed cell death 7.54381777672116e-06 2143 56 22 0.392857142857143 0.0102659822678488
GO:BP GO:0031324 negative regulation of cellular metabolic process 8.81007470234463e-06 2719 43 21 0.488372093023256 0.00772342773078338
GO:BP GO:0031647 regulation of protein stability 1.21853823530987e-05 300 40 8 0.2 0.0266666666666667
GO:BP GO:0080090 regulation of primary metabolic process 1.21853823530987e-05 6053 67 43 0.641791044776119 0.00710391541384437
GO:BP GO:1903320 regulation of protein modification by small protein conjugation or removal 1.21853823530987e-05 243 21 6 0.285714285714286 0.0246913580246914
GO:BP GO:0051246 regulation of protein metabolic process 1.21853823530987e-05 2704 62 26 0.419354838709677 0.00961538461538462
GO:BP GO:0051172 negative regulation of nitrogen compound metabolic process 1.21901556489872e-05 2518 43 20 0.465116279069767 0.0079428117553614
GO:BP GO:0062197 cellular response to chemical stress 1.28312464706226e-05 365 15 6 0.4 0.0164383561643836
GO:BP GO:0071900 regulation of protein serine/threonine kinase activity 1.49523069470352e-05 503 56 11 0.196428571428571 0.0218687872763419
GO:BP GO:0043549 regulation of kinase activity 1.53205127169453e-05 921 62 15 0.241935483870968 0.0162866449511401
GO:BP GO:0051345 positive regulation of hydrolase activity 1.64361989206742e-05 783 13 7 0.538461538461538 0.00893997445721584
GO:BP GO:0051131 chaperone-mediated protein complex assembly 1.64762561920522e-05 21 13 3 0.230769230769231 0.142857142857143
GO:BP GO:0071345 cellular response to cytokine stimulus 1.74364515698841e-05 1132 18 9 0.5 0.00795053003533569
GO:BP GO:0097191 extrinsic apoptotic signaling pathway 1.75141069167604e-05 223 125 11 0.088 0.0493273542600897
GO:BP GO:0002753 cytoplasmic pattern recognition receptor signaling pathway 1.76470443924601e-05 73 16 4 0.25 0.0547945205479452
GO:BP GO:0045859 regulation of protein kinase activity 1.80836558421719e-05 809 62 14 0.225806451612903 0.0173053152039555
GO:BP GO:0043488 regulation of mRNA stability 1.956683179622e-05 191 16 5 0.3125 0.0261780104712042
GO:BP GO:0030308 negative regulation of cell growth 2.23570470380748e-05 192 92 9 0.0978260869565217 0.046875
GO:BP GO:0051348 negative regulation of transferase activity 2.23570470380748e-05 310 43 8 0.186046511627907 0.0258064516129032
GO:BP GO:0006402 mRNA catabolic process 2.23570470380748e-05 384 16 6 0.375 0.015625
GO:BP GO:0043487 regulation of RNA stability 2.36373668805808e-05 201 16 5 0.3125 0.0248756218905473
GO:BP GO:0050896 response to stimulus 2.36373668805808e-05 9407 31 29 0.935483870967742 0.00308281067290316
GO:BP GO:0045926 negative regulation of growth 2.44459753391371e-05 255 92 10 0.108695652173913 0.0392156862745098
GO:BP GO:0060255 regulation of macromolecule metabolic process 2.44459753391371e-05 6603 49 35 0.714285714285714 0.00530062092988036
GO:BP GO:0031323 regulation of cellular metabolic process 2.61871689256996e-05 6269 67 43 0.641791044776119 0.00685914818950391
GO:BP GO:0002221 pattern recognition receptor signaling pathway 2.93131235412753e-05 213 16 5 0.3125 0.0234741784037559
GO:BP GO:0061013 regulation of mRNA catabolic process 2.93131235412753e-05 213 16 5 0.3125 0.0234741784037559
GO:BP GO:0006401 RNA catabolic process 3.54405068284934e-05 424 16 6 0.375 0.0141509433962264
GO:BP GO:0051171 regulation of nitrogen compound metabolic process 3.55212887338492e-05 5848 67 41 0.611940298507463 0.0070109439124487
GO:BP GO:0010556 regulation of macromolecule biosynthetic process 3.61907343521801e-05 4102 18 14 0.777777777777778 0.00341296928327645
GO:BP GO:0019222 regulation of metabolic process 3.73527353072908e-05 7148 35 28 0.8 0.00391717963066592
GO:BP GO:0006979 response to oxidative stress 3.75119101634854e-05 466 15 6 0.4 0.0128755364806867
GO:BP GO:0043281 regulation of cysteine-type endopeptidase activity involved in apoptotic process 4.2207451625282e-05 217 90 9 0.1 0.0414746543778802
GO:BP GO:2001233 regulation of apoptotic signaling pathway 4.37360942856034e-05 363 125 13 0.104 0.0358126721763085
GO:BP GO:0097190 apoptotic signaling pathway 4.60141255256738e-05 600 90 14 0.155555555555556 0.0233333333333333
GO:BP GO:2001236 regulation of extrinsic apoptotic signaling pathway 4.92993824239677e-05 159 125 9 0.072 0.0566037735849057
GO:BP GO:0031399 regulation of protein modification process 5.29089583377665e-05 1671 62 19 0.306451612903226 0.0113704368641532
GO:BP GO:0060548 negative regulation of cell death 5.29089583377665e-05 1038 17 8 0.470588235294118 0.00770712909441233
GO:BP GO:0048523 negative regulation of cellular process 5.40200281966677e-05 5139 38 25 0.657894736842105 0.00486475968087176
GO:BP GO:0032273 positive regulation of protein polymerization 5.50094697456593e-05 141 4 3 0.75 0.0212765957446809
GO:BP GO:0009892 negative regulation of metabolic process 5.57674194000231e-05 3479 31 18 0.580645161290323 0.00517390054613395
GO:BP GO:0006469 negative regulation of protein kinase activity 5.57674194000231e-05 251 43 7 0.162790697674419 0.0278884462151394
GO:BP GO:0044092 negative regulation of molecular function 6.39724619519118e-05 1219 69 17 0.246376811594203 0.0139458572600492
GO:BP GO:0061684 chaperone-mediated autophagy 6.39724619519118e-05 16 30 3 0.1 0.1875
GO:BP GO:0048522 positive regulation of cellular process 6.39724619519118e-05 5757 17 15 0.882352941176471 0.00260552371026576
GO:BP GO:1903364 positive regulation of cellular protein catabolic process 6.60062038259965e-05 154 4 3 0.75 0.0194805194805195
GO:BP GO:0032781 positive regulation of ATPase activity 6.60062038259965e-05 57 123 6 0.0487804878048781 0.105263157894737
GO:BP GO:0009889 regulation of biosynthetic process 6.60062038259965e-05 4361 18 14 0.777777777777778 0.00321027287319422
GO:BP GO:0051090 regulation of DNA-binding transcription factor activity 7.08039162118985e-05 456 61 10 0.163934426229508 0.0219298245614035
GO:BP GO:0097192 extrinsic apoptotic signaling pathway in absence of ligand 7.08039162118985e-05 71 56 5 0.0892857142857143 0.0704225352112676
GO:BP GO:0038034 signal transduction in absence of ligand 7.08039162118985e-05 71 56 5 0.0892857142857143 0.0704225352112676
GO:BP GO:0010604 positive regulation of macromolecule metabolic process 7.20172832852252e-05 3483 21 14 0.666666666666667 0.00401952339936836
GO:BP GO:0044087 regulation of cellular component biogenesis 7.27636592730588e-05 990 6 5 0.833333333333333 0.00505050505050505
GO:BP GO:2000116 regulation of cysteine-type endopeptidase activity 7.68826838388623e-05 240 90 9 0.1 0.0375
GO:BP GO:0030522 intracellular receptor signaling pathway 8.69023748153292e-05 284 16 5 0.3125 0.0176056338028169
GO:BP GO:0033673 negative regulation of kinase activity 8.69023748153292e-05 275 43 7 0.162790697674419 0.0254545454545455
GO:BP GO:0050821 protein stabilization 9.22446590946512e-05 193 40 6 0.15 0.0310880829015544
GO:BP GO:0001775 cell activation 9.60995525386876e-05 1495 14 8 0.571428571428571 0.00535117056856187
GO:BP GO:0034599 cellular response to oxidative stress 9.62287832435697e-05 316 15 5 0.333333333333333 0.0158227848101266
GO:BP GO:0002755 MyD88-dependent toll-like receptor signaling pathway 0.000101168413756296 37 16 3 0.1875 0.0810810810810811
GO:BP GO:0031329 regulation of cellular catabolic process 0.00010144207794252 866 16 7 0.4375 0.00808314087759815
GO:BP GO:0042769 DNA damage response, detection of DNA damage 0.000116163742827416 39 16 3 0.1875 0.0769230769230769
GO:BP GO:0043405 regulation of MAP kinase activity 0.000122420443779834 316 56 8 0.142857142857143 0.0253164556962025
GO:BP GO:0034655 nucleobase-containing compound catabolic process 0.000125727972993867 567 16 6 0.375 0.0105820105820106
GO:BP GO:0002274 myeloid leukocyte activation 0.000126373217817196 667 14 6 0.428571428571429 0.00899550224887556
GO:BP GO:0043254 regulation of protein-containing complex assembly 0.000129631510293963 460 6 4 0.666666666666667 0.00869565217391304
GO:BP GO:0000185 activation of MAPKKK activity 0.000131399789650783 12 56 3 0.0535714285714286 0.25
GO:BP GO:0051716 cellular response to stimulus 0.000131894928307478 7781 18 17 0.944444444444444 0.00218480915049479
GO:BP GO:0045639 positive regulation of myeloid cell differentiation 0.000131894928307478 103 7 3 0.428571428571429 0.029126213592233
GO:BP GO:0043066 negative regulation of apoptotic process 0.000138470424036002 921 16 7 0.4375 0.00760043431053203
GO:BP GO:0051240 positive regulation of multicellular organismal process 0.000138470424036002 1455 15 8 0.533333333333333 0.00549828178694158
GO:BP GO:0072594 establishment of protein localization to organelle 0.000138720557560924 584 16 6 0.375 0.0102739726027397
GO:BP GO:1902531 regulation of intracellular signal transduction 0.000138925730155527 1842 16 9 0.5625 0.00488599348534202
GO:BP GO:0006468 protein phosphorylation 0.000139480355560555 1668 56 17 0.303571428571429 0.0101918465227818
GO:BP GO:0035556 intracellular signal transduction 0.000139480355560555 2772 47 20 0.425531914893617 0.00721500721500722
GO:BP GO:0031400 negative regulation of protein modification process 0.000139806782756946 578 43 9 0.209302325581395 0.0155709342560554
GO:BP GO:0043312 neutrophil degranulation 0.000143566815400676 482 6 4 0.666666666666667 0.00829875518672199
GO:BP GO:0002283 neutrophil activation involved in immune response 0.000146171703616179 485 6 4 0.666666666666667 0.00824742268041237
GO:BP GO:0016049 cell growth 0.000148843062455865 495 92 12 0.130434782608696 0.0242424242424242
GO:BP GO:0009893 positive regulation of metabolic process 0.000148843062455865 3783 21 14 0.666666666666667 0.00370076658736453
GO:BP GO:0043069 negative regulation of programmed cell death 0.000149465450184607 943 16 7 0.4375 0.00742311770943796
GO:BP GO:0046700 heterocycle catabolic process 0.000152497178634392 602 16 6 0.375 0.00996677740863787
GO:BP GO:0051336 regulation of hydrolase activity 0.000152497178634392 1321 77 18 0.233766233766234 0.0136260408781226
GO:BP GO:0048518 positive regulation of biological process 0.000152954418684621 6363 44 30 0.681818181818182 0.00471475719000472
GO:BP GO:0002446 neutrophil mediated immunity 0.000152954418684621 497 6 4 0.666666666666667 0.00804828973843058
GO:BP GO:0042119 neutrophil activation 0.000153215386711115 498 6 4 0.666666666666667 0.00803212851405622
GO:BP GO:0044270 cellular nitrogen compound catabolic process 0.000156901835190964 608 16 6 0.375 0.00986842105263158
GO:BP GO:0036230 granulocyte activation 0.000157712818192192 504 6 4 0.666666666666667 0.00793650793650794
GO:BP GO:0032271 regulation of protein polymerization 0.00015863067594212 236 4 3 0.75 0.0127118644067797
GO:BP GO:0002366 leukocyte activation involved in immune response 0.00015863067594212 717 14 6 0.428571428571429 0.00836820083682008
GO:BP GO:0045732 positive regulation of protein catabolic process 0.000159689868153962 237 4 3 0.75 0.0126582278481013
GO:BP GO:0043086 negative regulation of catalytic activity 0.000159976298088626 851 56 12 0.214285714285714 0.0141010575793184
GO:BP GO:0002263 cell activation involved in immune response 0.000160082682394024 721 14 6 0.428571428571429 0.00832177531206657
GO:BP GO:0019439 aromatic compound catabolic process 0.000172413832086628 623 16 6 0.375 0.00963081861958266
GO:BP GO:2000112 regulation of cellular macromolecule biosynthetic process 0.000173860859679928 4071 18 13 0.722222222222222 0.00319331859493982
GO:BP GO:0019058 viral life cycle 0.000175852061376528 353 16 5 0.3125 0.0141643059490085
GO:BP GO:0051092 positive regulation of NF-kappaB transcription factor activity 0.000178039579378855 162 16 4 0.25 0.0246913580246914
GO:BP GO:1903311 regulation of mRNA metabolic process 0.000178039579378855 356 16 5 0.3125 0.0140449438202247
GO:BP GO:0001558 regulation of cell growth 0.000178039579378855 426 92 11 0.119565217391304 0.0258215962441315
GO:BP GO:0001819 positive regulation of cytokine production 0.000178039579378855 452 13 5 0.384615384615385 0.0110619469026549
GO:BP GO:0043299 leukocyte degranulation 0.000182983835224367 535 6 4 0.666666666666667 0.00747663551401869
GO:BP GO:0031397 negative regulation of protein ubiquitination 0.00018384404909463 83 10 3 0.3 0.036144578313253
GO:BP GO:1903362 regulation of cellular protein catabolic process 0.000187816913093632 257 4 3 0.75 0.0116731517509728
GO:BP GO:2001242 regulation of intrinsic apoptotic signaling pathway 0.000194426329604125 167 16 4 0.25 0.0239520958083832
GO:BP GO:0002275 myeloid cell activation involved in immune response 0.000195403243110548 547 6 4 0.666666666666667 0.00731261425959781
GO:BP GO:0031334 positive regulation of protein-containing complex assembly 0.000196908565257059 263 4 3 0.75 0.0114068441064639
GO:BP GO:0002444 myeloid leukocyte mediated immunity 0.000197863720881514 551 6 4 0.666666666666667 0.00725952813067151
GO:BP GO:1901361 organic cyclic compound catabolic process 0.000201399510843021 651 16 6 0.375 0.00921658986175115
GO:BP GO:2001234 negative regulation of apoptotic signaling pathway 0.00020609823973372 236 12 4 0.333333333333333 0.0169491525423729
GO:BP GO:0031326 regulation of cellular biosynthetic process 0.000207809193196316 4273 67 32 0.477611940298507 0.00748888368827522
GO:BP GO:0001932 regulation of protein phosphorylation 0.000217050025194306 1240 62 15 0.241935483870968 0.0120967741935484
GO:BP GO:0009894 regulation of catabolic process 0.00021855366743385 1033 16 7 0.4375 0.00677637947725073
GO:BP GO:0010608 posttranscriptional regulation of gene expression 0.00021855366743385 896 18 7 0.388888888888889 0.0078125
GO:BP GO:0009890 negative regulation of biosynthetic process 0.000228741594550876 1740 18 9 0.5 0.00517241379310345
GO:BP GO:0010605 negative regulation of macromolecule metabolic process 0.000228741594550876 3241 43 20 0.465116279069767 0.00617093489663684
GO:BP GO:0044419 biological process involved in interspecies interaction between organisms 0.000228741594550876 2255 18 10 0.555555555555556 0.00443458980044346
GO:BP GO:0030162 regulation of proteolysis 0.000237126262079787 752 77 13 0.168831168831169 0.0172872340425532
GO:BP GO:0051248 negative regulation of protein metabolic process 0.000250656590191044 1151 92 18 0.195652173913043 0.0156385751520417
GO:BP GO:1903321 negative regulation of protein modification by small protein conjugation or removal 0.000256185885516897 96 10 3 0.3 0.03125
GO:BP GO:0048519 negative regulation of biological process 0.000256802486199402 5757 38 25 0.657894736842105 0.00434253951710961
GO:BP GO:0043462 regulation of ATPase activity 0.000260122912990645 80 123 6 0.0487804878048781 0.075
GO:BP GO:0042325 regulation of phosphorylation 0.000264325370386842 1431 62 16 0.258064516129032 0.0111809923130678
GO:BP GO:0009059 macromolecule biosynthetic process 0.00027202546463 5114 18 14 0.777777777777778 0.00273758310520141
GO:BP GO:0051258 protein polymerization 0.000276953364202449 305 4 3 0.75 0.00983606557377049
GO:BP GO:0019221 cytokine-mediated signaling pathway 0.000281138313447935 810 9 5 0.555555555555556 0.00617283950617284
GO:BP GO:0032269 negative regulation of cellular protein metabolic process 0.000285091677526657 1082 56 13 0.232142857142857 0.0120147874306839
GO:BP GO:0006810 transport 0.000302784211791678 5224 16 13 0.8125 0.0024885145482389
GO:BP GO:0071901 negative regulation of protein serine/threonine kinase activity 0.00034857541855781 150 42 5 0.119047619047619 0.0333333333333333
GO:BP GO:0045321 leukocyte activation 0.000353448339354416 1332 14 7 0.5 0.00525525525525526
GO:BP GO:0001933 negative regulation of protein phosphorylation 0.000358386758177919 373 43 7 0.162790697674419 0.0187667560321716
GO:BP GO:0007254 JNK cascade 0.000360603991015214 195 33 5 0.151515151515152 0.0256410256410256
GO:BP GO:0051641 cellular localization 0.000362040055168413 3541 16 11 0.6875 0.00310646709968935
GO:BP GO:0051649 establishment of localization in cell 0.000364140055910713 2813 16 10 0.625 0.00355492356914326
GO:BP GO:0007179 transforming growth factor beta receptor signaling pathway 0.000370297637304964 206 16 4 0.25 0.0194174757281553
GO:BP GO:0016192 vesicle-mediated transport 0.000373435396212211 2180 16 9 0.5625 0.00412844036697248
GO:BP GO:0051128 regulation of cellular component organization 0.000375510507304827 2412 125 34 0.272 0.0140961857379768
GO:BP GO:0002443 leukocyte mediated immunity 0.000375510507304827 877 14 6 0.428571428571429 0.00684150513112885
GO:BP GO:0051726 regulation of cell cycle 0.000375510507304827 1236 7 5 0.714285714285714 0.0040453074433657
GO:BP GO:0051234 establishment of localization 0.000395596544780276 5372 16 13 0.8125 0.00241995532390171
GO:BP GO:0006605 protein targeting 0.000396797622125986 441 16 5 0.3125 0.0113378684807256
GO:BP GO:0006886 intracellular protein transport 0.000458937124504778 1186 16 7 0.4375 0.00590219224283305
GO:BP GO:2001243 negative regulation of intrinsic apoptotic signaling pathway 0.00045968375096882 100 12 3 0.25 0.03
GO:BP GO:0051129 negative regulation of cellular component organization 0.000460925626620703 759 106 15 0.141509433962264 0.0197628458498024
GO:BP GO:0051702 biological process involved in interaction with symbiont 0.000515488762568504 96 13 3 0.230769230769231 0.03125
GO:BP GO:0031331 positive regulation of cellular catabolic process 0.000515768585433651 393 4 3 0.75 0.00763358778625954
GO:BP GO:0042176 regulation of protein catabolic process 0.000538603823711389 401 4 3 0.75 0.00748129675810474
GO:BP GO:0016567 protein ubiquitination 0.000549318342589366 892 21 7 0.333333333333333 0.007847533632287
GO:BP GO:0044265 cellular macromolecule catabolic process 0.000549794002869454 1231 16 7 0.4375 0.00568643379366369
GO:BP GO:0071705 nitrogen compound transport 0.000562592139099095 2322 16 9 0.5625 0.00387596899224806
GO:BP GO:0030163 protein catabolic process 0.000579506744652454 974 9 5 0.555555555555556 0.00513347022587269
GO:BP GO:0045055 regulated exocytosis 0.000604536280935277 785 6 4 0.666666666666667 0.00509554140127389
GO:BP GO:1903507 negative regulation of nucleic acid-templated transcription 0.000628461082005507 1339 57 14 0.245614035087719 0.0104555638536221
GO:BP GO:0043154 negative regulation of cysteine-type endopeptidase activity involved in apoptotic process 0.000630747654716241 81 90 5 0.0555555555555556 0.0617283950617284
GO:BP GO:1902679 negative regulation of RNA biosynthetic process 0.000631103176643595 1341 57 14 0.245614035087719 0.0104399701715138
GO:BP GO:0042326 negative regulation of phosphorylation 0.000649444465852934 420 43 7 0.162790697674419 0.0166666666666667
GO:BP GO:0010558 negative regulation of macromolecule biosynthetic process 0.000687751677501419 1639 66 17 0.257575757575758 0.0103721781574131
GO:BP GO:0030512 negative regulation of transforming growth factor beta receptor signaling pathway 0.00070598962647338 88 16 3 0.1875 0.0340909090909091
GO:BP GO:0016310 phosphorylation 0.000713923038715999 2138 62 19 0.306451612903226 0.00888681010289991
GO:BP GO:0052548 regulation of endopeptidase activity 0.000724503659509303 437 90 10 0.111111111111111 0.022883295194508
GO:BP GO:0071560 cellular response to transforming growth factor beta stimulus 0.000727452704472335 256 16 4 0.25 0.015625
GO:BP GO:0016071 mRNA metabolic process 0.000759654666609131 874 16 6 0.375 0.0068649885583524
GO:BP GO:0009896 positive regulation of catabolic process 0.000759654666609131 464 4 3 0.75 0.00646551724137931
GO:BP GO:0071559 response to transforming growth factor beta 0.000780835516391924 262 16 4 0.25 0.0152671755725191
GO:BP GO:0007017 microtubule-based process 0.000783933581960888 881 16 6 0.375 0.00681044267877412
GO:BP GO:0032446 protein modification by small protein conjugation 0.000849000765453165 973 21 7 0.333333333333333 0.00719424460431655
GO:BP GO:0051091 positive regulation of DNA-binding transcription factor activity 0.00085476261303513 270 16 4 0.25 0.0148148148148148
GO:BP GO:0010628 positive regulation of gene expression 0.000881870737373926 1160 13 6 0.461538461538462 0.00517241379310345
GO:BP GO:2000117 negative regulation of cysteine-type endopeptidase activity 0.000899428147490365 89 90 5 0.0555555555555556 0.0561797752808989
GO:BP GO:0009968 negative regulation of signal transduction 0.000930546191899694 1364 16 7 0.4375 0.00513196480938416
GO:BP GO:0051247 positive regulation of protein metabolic process 0.000932161246124839 1564 34 11 0.323529411764706 0.00703324808184143
GO:BP GO:0006887 exocytosis 0.000934499811802951 904 6 4 0.666666666666667 0.00442477876106195
GO:BP GO:0007049 cell cycle 0.000941768806553415 1902 16 8 0.5 0.00420609884332282
GO:BP GO:0072655 establishment of protein localization to mitochondrion 0.000946714381118449 143 30 4 0.133333333333333 0.027972027972028
GO:BP GO:0045862 positive regulation of proteolysis 0.000947669916513076 378 5 3 0.6 0.00793650793650794
GO:BP GO:0008637 apoptotic mitochondrial changes 0.00096514275564606 126 13 3 0.230769230769231 0.0238095238095238
GO:BP GO:0031327 negative regulation of cellular biosynthetic process 0.00101252688264783 1707 66 17 0.257575757575758 0.00995899238429994
GO:BP GO:0032270 positive regulation of cellular protein metabolic process 0.00101252688264783 1477 25 9 0.36 0.00609343263371699
GO:BP GO:0015031 protein transport 0.00101252688264783 1929 16 8 0.5 0.00414722654224987
GO:BP GO:0019220 regulation of phosphate metabolic process 0.00101252688264783 1645 62 16 0.258064516129032 0.00972644376899696
GO:BP GO:0051174 regulation of phosphorus metabolic process 0.00101252688264783 1645 62 16 0.258064516129032 0.00972644376899696
GO:BP GO:0070585 protein localization to mitochondrion 0.00101344448599634 147 30 4 0.133333333333333 0.0272108843537415
GO:BP GO:0007041 lysosomal transport 0.00101344448599634 111 15 3 0.2 0.027027027027027
GO:BP GO:0046034 ATP metabolic process 0.00103565287455002 314 6 3 0.5 0.00955414012738853
GO:BP GO:0045637 regulation of myeloid cell differentiation 0.0010546663101755 263 7 3 0.428571428571429 0.0114068441064639
GO:BP GO:0044089 positive regulation of cellular component biogenesis 0.00106418591808572 540 4 3 0.75 0.00555555555555556
GO:BP GO:0097193 intrinsic apoptotic signaling pathway 0.00108413806439767 294 16 4 0.25 0.0136054421768707
GO:BP GO:0052547 regulation of peptidase activity 0.00108590799780084 467 90 10 0.111111111111111 0.0214132762312634
GO:BP GO:0051173 positive regulation of nitrogen compound metabolic process 0.00108969821973408 3083 9 7 0.777777777777778 0.00227051573143042
GO:BP GO:0015833 peptide transport 0.00112700022830936 1971 16 8 0.5 0.00405885337392187
GO:BP GO:0051261 protein depolymerization 0.00116730068258169 117 118 6 0.0508474576271186 0.0512820512820513
GO:BP GO:0065008 regulation of biological quality 0.00116730068258169 4131 16 11 0.6875 0.00266279351246672
GO:BP GO:0051253 negative regulation of RNA metabolic process 0.00116730068258169 1445 57 14 0.245614035087719 0.00968858131487889
GO:BP GO:0034645 cellular macromolecule biosynthetic process 0.00116757902041893 5051 18 13 0.722222222222222 0.00257374777271827
GO:BP GO:0051403 stress-activated MAPK cascade 0.00122345678560186 272 33 5 0.151515151515152 0.0183823529411765
GO:BP GO:0042886 amide transport 0.00124947159603647 2007 16 8 0.5 0.00398604882909816
GO:BP GO:0010629 negative regulation of gene expression 0.00127266680701019 1460 16 7 0.4375 0.00479452054794521
GO:BP GO:0034613 cellular protein localization 0.00127266680701019 2014 16 8 0.5 0.00397219463753724
GO:BP GO:0010648 negative regulation of cell communication 0.00130582650722907 1468 16 7 0.4375 0.00476839237057221
GO:BP GO:0070727 cellular macromolecule localization 0.00130582650722907 2024 16 8 0.5 0.00395256916996047
GO:BP GO:0009057 macromolecule catabolic process 0.00130582650722907 1468 16 7 0.4375 0.00476839237057221
GO:BP GO:2001235 positive regulation of apoptotic signaling pathway 0.00131156801029396 129 110 6 0.0545454545454545 0.0465116279069767
GO:BP GO:0023057 negative regulation of signaling 0.00131271758000813 1471 16 7 0.4375 0.00475866757307954
GO:BP GO:0045184 establishment of protein localization 0.00134016190337453 2035 16 8 0.5 0.00393120393120393
GO:BP GO:0010970 transport along microtubule 0.00140129251039948 164 30 4 0.133333333333333 0.024390243902439
GO:BP GO:0043242 negative regulation of protein-containing complex disassembly 0.00140581694564173 86 106 5 0.0471698113207547 0.0581395348837209
GO:BP GO:0033365 protein localization to organelle 0.00142207643409511 1017 16 6 0.375 0.00589970501474926
GO:BP GO:0006839 mitochondrial transport 0.00147232227535455 284 74 7 0.0945945945945946 0.0246478873239437
GO:BP GO:0031325 positive regulation of cellular metabolic process 0.00148063908694225 3274 9 7 0.777777777777778 0.00213805742211362
GO:BP GO:0031098 stress-activated protein kinase signaling cascade 0.00148621832753361 288 33 5 0.151515151515152 0.0173611111111111
GO:BP GO:2000113 negative regulation of cellular macromolecule biosynthetic process 0.00148621832753361 1628 11 6 0.545454545454545 0.00368550368550369
GO:BP GO:0001817 regulation of cytokine production 0.0015027264090275 806 13 5 0.384615384615385 0.00620347394540943
GO:BP GO:0040008 regulation of growth 0.00151066047708149 681 92 12 0.130434782608696 0.0176211453744493
GO:BP GO:0071496 cellular response to external stimulus 0.00151066047708149 322 66 7 0.106060606060606 0.0217391304347826
GO:BP GO:0043244 regulation of protein-containing complex disassembly 0.00151143110928288 125 118 6 0.0508474576271186 0.048
GO:BP GO:0071702 organic substance transport 0.001629362003341 2766 16 9 0.5625 0.00325379609544469
GO:BP GO:0017015 regulation of transforming growth factor beta receptor signaling pathway 0.00163348158862393 129 16 3 0.1875 0.0232558139534884
GO:BP GO:1902903 regulation of supramolecular fiber organization 0.00163348158862393 387 6 3 0.5 0.00775193798449612
GO:BP GO:1903844 regulation of cellular response to transforming growth factor beta stimulus 0.00174312785533638 132 16 3 0.1875 0.0227272727272727
GO:BP GO:0001816 cytokine production 0.0017902276401955 844 13 5 0.384615384615385 0.00592417061611374
GO:BP GO:2001238 positive regulation of extrinsic apoptotic signaling pathway 0.0017902276401955 48 110 4 0.0363636363636364 0.0833333333333333
GO:BP GO:0045892 negative regulation of transcription, DNA-templated 0.00181096481504554 1337 57 13 0.228070175438596 0.00972326103216156
GO:BP GO:0090101 negative regulation of transmembrane receptor protein serine/threonine kinase signaling pathway 0.00187627620794511 136 16 3 0.1875 0.0220588235294118
GO:BP GO:1901576 organic substance biosynthetic process 0.00188799901111409 6248 18 14 0.777777777777778 0.00224071702944942
GO:BP GO:0070647 protein modification by small protein conjugation or removal 0.00194667123736824 1184 10 5 0.5 0.00422297297297297
GO:BP GO:1901565 organonitrogen compound catabolic process 0.00197067129375656 1358 9 5 0.555555555555556 0.00368188512518409
GO:BP GO:0042542 response to hydrogen peroxide 0.00201196528642075 150 15 3 0.2 0.02
GO:BP GO:0007167 enzyme linked receptor protein signaling pathway 0.00201999365998658 1103 16 6 0.375 0.00543970988213962
GO:BP GO:0045934 negative regulation of nucleobase-containing compound metabolic process 0.00204355355439809 1548 57 14 0.245614035087719 0.00904392764857881
GO:BP GO:0034622 cellular protein-containing complex assembly 0.00204883291906016 1107 16 6 0.375 0.00542005420054201
GO:BP GO:0045936 negative regulation of phosphate metabolic process 0.00209327047003413 543 56 8 0.142857142857143 0.0147329650092081
GO:BP GO:0010563 negative regulation of phosphorus metabolic process 0.00210769062842263 544 56 8 0.142857142857143 0.0147058823529412
GO:BP GO:0002682 regulation of immune system process 0.00210769062842263 1617 8 5 0.625 0.00309214594928881
GO:BP GO:0043280 positive regulation of cysteine-type endopeptidase activity involved in apoptotic process 0.00211280409345114 138 74 5 0.0675675675675676 0.036231884057971
GO:BP GO:0007178 transmembrane receptor protein serine/threonine kinase signaling pathway 0.00211787429807382 369 16 4 0.25 0.010840108401084
GO:BP GO:0002252 immune effector process 0.00211787429807382 1309 14 6 0.428571428571429 0.00458365164247517
GO:BP GO:0007034 vacuolar transport 0.00211787429807382 154 15 3 0.2 0.0194805194805195
GO:BP GO:0006820 anion transport 0.00213555062709783 2889 16 9 0.5625 0.00311526479750779
GO:BP GO:0009058 biosynthetic process 0.00214905749696256 6340 18 14 0.777777777777778 0.00220820189274448
GO:BP GO:0008625 extrinsic apoptotic signaling pathway via death domain receptors 0.00224163415434222 83 125 5 0.04 0.0602409638554217
GO:BP GO:0007018 microtubule-based movement 0.00238241217628721 383 16 4 0.25 0.010443864229765
GO:BP GO:1901879 regulation of protein depolymerization 0.00246304689277608 90 118 5 0.0423728813559322 0.0555555555555556
GO:BP GO:0099111 microtubule-based transport 0.00246304689277608 198 30 4 0.133333333333333 0.0202020202020202
GO:BP GO:0009409 response to cold 0.00251883252739135 48 123 4 0.032520325203252 0.0833333333333333
GO:BP GO:0065003 protein-containing complex assembly 0.00251883252739135 1680 16 7 0.4375 0.00416666666666667
GO:BP GO:0044271 cellular nitrogen compound biosynthetic process 0.002538574574614 5017 13 10 0.769230769230769 0.00199322304165836
GO:BP GO:0071363 cellular response to growth factor stimulus 0.002538574574614 731 16 5 0.3125 0.00683994528043776
GO:BP GO:0030705 cytoskeleton-dependent intracellular transport 0.00260924706447246 202 30 4 0.133333333333333 0.0198019801980198
GO:BP GO:0032984 protein-containing complex disassembly 0.00262346052569135 333 118 9 0.076271186440678 0.027027027027027
GO:BP GO:0043170 macromolecule metabolic process 0.00264529916948449 9796 13 13 1 0.00132707227439771
GO:BP GO:1902532 negative regulation of intracellular signal transduction 0.00266689046930204 549 12 4 0.333333333333333 0.00728597449908925
GO:BP GO:0019219 regulation of nucleobase-containing compound metabolic process 0.00267528051992344 4091 67 28 0.417910447761194 0.00684429234905891
GO:BP GO:0010564 regulation of cell cycle process 0.00267637244732144 809 4 3 0.75 0.00370828182941904
GO:BP GO:0017038 protein import 0.00269559258932349 205 30 4 0.133333333333333 0.0195121951219512
GO:BP GO:0044257 cellular protein catabolic process 0.00270192484191955 813 4 3 0.75 0.003690036900369
GO:BP GO:2000106 regulation of leukocyte apoptotic process 0.00272922460010884 82 74 4 0.0540540540540541 0.0487804878048781
GO:BP GO:0002224 toll-like receptor signaling pathway 0.00273591960919438 161 16 3 0.1875 0.0186335403726708
GO:BP GO:0000122 negative regulation of transcription by RNA polymerase II 0.00289847644184921 901 66 11 0.166666666666667 0.0122086570477248
GO:BP GO:0070848 response to growth factor 0.00289847644184921 759 16 5 0.3125 0.00658761528326746
GO:BP GO:0048585 negative regulation of response to stimulus 0.00290852239908565 1733 16 7 0.4375 0.00403923831506059
GO:BP GO:0018105 peptidyl-serine phosphorylation 0.00303519962877993 313 56 6 0.107142857142857 0.0191693290734824
GO:BP GO:1903706 regulation of hemopoiesis 0.00314308961829621 424 7 3 0.428571428571429 0.00707547169811321
GO:BP GO:2001056 positive regulation of cysteine-type endopeptidase activity 0.00315374634292903 154 74 5 0.0675675675675676 0.0324675324675325
GO:BP GO:0032940 secretion by cell 0.00319365422915539 1364 6 4 0.666666666666667 0.00293255131964809
GO:BP GO:0030099 myeloid cell differentiation 0.00320687837213945 428 7 3 0.428571428571429 0.00700934579439252
GO:BP GO:0046907 intracellular transport 0.00321540148136169 1767 16 7 0.4375 0.00396151669496321
GO:BP GO:0010468 regulation of gene expression 0.00324676950034475 5196 13 10 0.769230769230769 0.00192455735180908
GO:BP GO:0070925 organelle assembly 0.00344317972018135 895 4 3 0.75 0.00335195530726257
GO:BP GO:0051347 positive regulation of transferase activity 0.00345998096589044 689 61 9 0.147540983606557 0.0130624092888244
GO:BP GO:0043161 proteasome-mediated ubiquitin-dependent protein catabolic process 0.00347951239205431 434 16 4 0.25 0.00921658986175115
GO:BP GO:1903047 mitotic cell cycle process 0.00358483920738632 911 4 3 0.75 0.00329308452250274
GO:BP GO:0140352 export from cell 0.00361313136677743 1418 6 4 0.666666666666667 0.00282087447108604
GO:BP GO:0009719 response to endogenous stimulus 0.00361472543849505 1683 17 7 0.411764705882353 0.0041592394533571
GO:BP GO:0007005 mitochondrion organization 0.00377763566523 561 13 4 0.307692307692308 0.0071301247771836
GO:BP GO:0009966 regulation of signal transduction 0.00379595572582589 3165 16 9 0.5625 0.0028436018957346
GO:BP GO:0051179 localization 0.00386681885375164 6901 16 13 0.8125 0.00188378495870164
GO:BP GO:0019538 protein metabolic process 0.00386681885375164 5808 37 22 0.594594594594595 0.00378787878787879
GO:BP GO:0006919 activation of cysteine-type endopeptidase activity involved in apoptotic process 0.00391741111008098 92 74 4 0.0540540540540541 0.0434782608695652
GO:BP GO:1901575 organic substance catabolic process 0.00393271966271003 2267 34 12 0.352941176470588 0.00529333921482135
GO:BP GO:0045661 regulation of myoblast differentiation 0.00396427175190427 52 56 3 0.0535714285714286 0.0576923076923077
GO:BP GO:0006955 immune response 0.00401329276431522 2311 7 5 0.714285714285714 0.00216356555603635
GO:BP GO:0006275 regulation of DNA replication 0.00401488597870642 111 62 4 0.0645161290322581 0.036036036036036
GO:BP GO:0018209 peptidyl-serine modification 0.00409379789624178 336 56 6 0.107142857142857 0.0178571428571429
GO:BP GO:0040007 growth 0.00410836755602211 967 4 3 0.75 0.0031023784901758
GO:BP GO:0044260 cellular macromolecule metabolic process 0.00419706576090689 8390 50 35 0.7 0.00417163289630513
GO:BP GO:1902533 positive regulation of intracellular signal transduction 0.00427036922101304 1037 61 11 0.180327868852459 0.0106075216972035
GO:BP GO:0006626 protein targeting to mitochondrion 0.00427036922101304 101 30 3 0.1 0.0297029702970297
GO:BP GO:0046903 secretion 0.00427436493707005 1501 6 4 0.666666666666667 0.00266489007328448
GO:BP GO:0071897 DNA biosynthetic process 0.00429534566237217 195 16 3 0.1875 0.0153846153846154
GO:BP GO:0051239 regulation of multicellular organismal process 0.00429821812956777 2861 21 10 0.476190476190476 0.0034952813701503
GO:BP GO:0022607 cellular component assembly 0.00448021159383588 3010 6 5 0.833333333333333 0.00166112956810631
GO:BP GO:1901564 organonitrogen compound metabolic process 0.00452117158847687 6792 37 24 0.648648648648649 0.00353356890459364
GO:BP GO:0044267 cellular protein metabolic process 0.00458922733684406 5229 56 28 0.5 0.00535475234270415
GO:BP GO:2000026 regulation of multicellular organismal development 0.00464390942961263 1447 15 6 0.4 0.00414651002073255
GO:BP GO:0002376 immune system process 0.00472765741840201 3278 8 6 0.75 0.00183038438071995
GO:BP GO:0043624 cellular protein complex disassembly 0.00472765741840201 226 118 7 0.0593220338983051 0.0309734513274336
GO:BP GO:0051252 regulation of RNA metabolic process 0.00475300513467433 3822 67 26 0.388059701492537 0.00680272108843537
GO:BP GO:0044248 cellular catabolic process 0.00503460937382162 2347 34 12 0.352941176470588 0.00511291009799744
GO:BP GO:0046328 regulation of JNK cascade 0.00504738754784077 133 56 4 0.0714285714285714 0.0300751879699248
GO:BP GO:0000278 mitotic cell cycle 0.00505779148433466 1059 4 3 0.75 0.0028328611898017
GO:BP GO:0043406 positive regulation of MAP kinase activity 0.0050971339212379 234 56 5 0.0892857142857143 0.0213675213675214
GO:BP GO:0072662 protein localization to peroxisome 0.00521004698591197 69 109 4 0.036697247706422 0.0579710144927536
GO:BP GO:0072663 establishment of protein localization to peroxisome 0.00521004698591197 69 109 4 0.036697247706422 0.0579710144927536
GO:BP GO:0006625 protein targeting to peroxisome 0.00521004698591197 69 109 4 0.036697247706422 0.0579710144927536
GO:BP GO:0032755 positive regulation of interleukin-6 production 0.00533011171381942 89 85 4 0.0470588235294118 0.0449438202247191
GO:BP GO:0043933 protein-containing complex subunit organization 0.00534881294806325 1963 16 7 0.4375 0.00356597045338767
GO:BP GO:0034654 nucleobase-containing compound biosynthetic process 0.00535058722113765 4199 9 7 0.777777777777778 0.00166706358656823
GO:BP GO:0061024 membrane organization 0.00544427690868722 973 9 4 0.444444444444444 0.00411099691675231
GO:BP GO:0043407 negative regulation of MAP kinase activity 0.00544945832562013 80 42 3 0.0714285714285714 0.0375
GO:BP GO:0042592 homeostatic process 0.00545735257920751 1981 40 12 0.3 0.0060575466935891
GO:BP GO:0000302 response to reactive oxygen species 0.00575409899438191 237 15 3 0.2 0.0126582278481013
GO:BP GO:0018130 heterocycle biosynthetic process 0.00585601536682465 4269 9 7 0.777777777777778 0.00163972827360037
GO:BP GO:0097435 supramolecular fiber organization 0.00589925461777147 734 29 6 0.206896551724138 0.00817438692098093
GO:BP GO:0019438 aromatic compound biosynthetic process 0.00589925461777147 4278 9 7 0.777777777777778 0.00163627863487611
GO:BP GO:1903037 regulation of leukocyte cell-cell adhesion 0.00599674676352872 338 61 6 0.0983606557377049 0.0177514792899408
GO:BP GO:0044085 cellular component biogenesis 0.00603951329741523 3257 6 5 0.833333333333333 0.00153515505066012
GO:BP GO:0032502 developmental process 0.00603951329741523 6628 17 13 0.764705882352941 0.00196137598068799
GO:BP GO:0044249 cellular biosynthetic process 0.0061326215678619 6154 68 36 0.529411764705882 0.00584985375365616
GO:BP GO:0043574 peroxisomal transport 0.00614666323902195 73 109 4 0.036697247706422 0.0547945205479452
GO:BP GO:0051130 positive regulation of cellular component organization 0.00614666323902195 1153 4 3 0.75 0.002601908065915
GO:BP GO:1901880 negative regulation of protein depolymerization 0.00614666323902195 75 106 4 0.0377358490566038 0.0533333333333333
GO:BP GO:0071887 leukocyte apoptotic process 0.00618583865432716 108 74 4 0.0540540540540541 0.037037037037037
GO:BP GO:0010950 positive regulation of endopeptidase activity 0.0062250184730809 187 74 5 0.0675675675675676 0.0267379679144385
GO:BP GO:0002761 regulation of myeloid leukocyte differentiation 0.00646918491600455 123 66 4 0.0606060606060606 0.032520325203252
GO:BP GO:0045935 positive regulation of nucleobase-containing compound metabolic process 0.00656670833554266 1887 9 5 0.555555555555556 0.00264970853206147
GO:BP GO:1901362 organic cyclic compound biosynthetic process 0.00702017299860949 4439 9 7 0.777777777777778 0.00157693174138319
GO:BP GO:0008104 protein localization 0.00714180367579682 2770 16 8 0.5 0.00288808664259928
GO:BP GO:0007165 signal transduction 0.00725321347893803 6309 16 12 0.75 0.0019020446980504
GO:BP GO:0071704 organic substance metabolic process 0.00726332055835448 11326 37 32 0.864864864864865 0.00282535758431927
GO:BP GO:0010646 regulation of cell communication 0.00726332055835448 3543 16 9 0.5625 0.00254022015241321
GO:BP GO:0002763 positive regulation of myeloid leukocyte differentiation 0.00753942668830187 59 66 3 0.0454545454545455 0.0508474576271186
GO:BP GO:1903039 positive regulation of leukocyte cell-cell adhesion 0.00753942668830187 241 61 5 0.0819672131147541 0.020746887966805
GO:BP GO:1903506 regulation of nucleic acid-templated transcription 0.00755581191354328 3535 67 24 0.358208955223881 0.00678925035360679
GO:BP GO:0043408 regulation of MAPK cascade 0.00762029573420151 730 42 7 0.166666666666667 0.00958904109589041
GO:BP GO:0023051 regulation of signaling 0.00764270200926298 3578 16 9 0.5625 0.00251537171604248
GO:BP GO:2001141 regulation of RNA biosynthetic process 0.00764270200926298 3540 67 24 0.358208955223881 0.00677966101694915
GO:BP GO:0090092 regulation of transmembrane receptor protein serine/threonine kinase signaling pathway 0.00785568136644003 257 16 3 0.1875 0.0116731517509728
GO:BP GO:0070228 regulation of lymphocyte apoptotic process 0.00832158689587349 55 74 3 0.0405405405405405 0.0545454545454545
GO:BP GO:0010952 positive regulation of peptidase activity 0.00852106153338463 205 74 5 0.0675675675675676 0.024390243902439
GO:BP GO:0006811 ion transport 0.00884334785457572 3661 16 9 0.5625 0.00245834471455886
GO:BP GO:0007166 cell surface receptor signaling pathway 0.00884334785457572 3210 9 6 0.666666666666667 0.00186915887850467
GO:BP GO:0007159 leukocyte cell-cell adhesion 0.00894577285274483 375 61 6 0.0983606557377049 0.016
GO:BP GO:0010951 negative regulation of endopeptidase activity 0.00905237085131803 253 90 6 0.0666666666666667 0.0237154150197628
GO:BP GO:0048731 system development 0.00924511708825406 5052 17 11 0.647058823529412 0.00217735550277118
GO:BP GO:0031398 positive regulation of protein ubiquitination 0.00935919022745243 120 77 4 0.051948051948052 0.0333333333333333
GO:BP GO:0010035 response to inorganic substance 0.00939122801643865 575 17 4 0.235294117647059 0.00695652173913044
GO:BP GO:0007031 peroxisome organization 0.00941740027490874 85 109 4 0.036697247706422 0.0470588235294118
GO:BP GO:0022411 cellular component disassembly 0.00959587546883213 571 123 11 0.0894308943089431 0.0192644483362522
GO:BP GO:0045670 regulation of osteoclast differentiation 0.00973076311369021 66 66 3 0.0454545454545455 0.0454545454545455
GO:BP GO:0043525 positive regulation of neuron apoptotic process 0.00975515364231511 59 74 3 0.0405405405405405 0.0508474576271186
GO:BP GO:0032635 interleukin-6 production 0.00988871801346952 172 92 5 0.0543478260869565 0.0290697674418605
GO:BP GO:0022402 cell cycle process 0.0100807359193877 1439 4 3 0.75 0.00208478109798471
GO:BP GO:0070266 necroptotic process 0.0102045595444929 46 97 3 0.0309278350515464 0.0652173913043478
GO:BP GO:0006446 regulation of translational initiation 0.0103493114884043 80 56 3 0.0535714285714286 0.0375
GO:BP GO:0007249 I-kappaB kinase/NF-kappaB signaling 0.0104634836314429 291 16 3 0.1875 0.0103092783505155
GO:BP GO:0010467 gene expression 0.010622843130855 6179 13 10 0.769230769230769 0.00161838485191779
GO:BP GO:0045861 negative regulation of proteolysis 0.0109425011549298 359 90 7 0.0777777777777778 0.0194986072423398
GO:BP GO:0010466 negative regulation of peptidase activity 0.0113053958002588 267 90 6 0.0666666666666667 0.0224719101123595
GO:BP GO:0045445 myoblast differentiation 0.011672298185579 84 56 3 0.0535714285714286 0.0357142857142857
GO:BP GO:0010594 regulation of endothelial cell migration 0.0120977115660694 244 20 3 0.15 0.0122950819672131
GO:BP GO:0048584 positive regulation of response to stimulus 0.0122828733006739 2344 16 7 0.4375 0.00298634812286689
GO:BP GO:0046889 positive regulation of lipid biosynthetic process 0.0123330696373594 88 115 4 0.0347826086956522 0.0454545454545455
GO:BP GO:0046330 positive regulation of JNK cascade 0.0123330696373594 86 56 3 0.0535714285714286 0.0348837209302326
GO:BP GO:0090287 regulation of cellular response to growth factor stimulus 0.0126256427784599 315 16 3 0.1875 0.00952380952380952
GO:BP GO:1903426 regulation of reactive oxygen species biosynthetic process 0.0126256427784599 111 92 4 0.0434782608695652 0.036036036036036
GO:BP GO:0071260 cellular response to mechanical stimulus 0.0126685325597539 80 61 3 0.0491803278688525 0.0375
GO:BP GO:0006796 phosphate-containing compound metabolic process 0.012685366522026 3087 62 20 0.32258064516129 0.00647878198898607
GO:BP GO:0071902 positive regulation of protein serine/threonine kinase activity 0.012685366522026 316 33 4 0.121212121212121 0.0126582278481013
GO:BP GO:0009967 positive regulation of signal transduction 0.0128900268868485 1598 4 3 0.75 0.00187734668335419
GO:BP GO:0006464 cellular protein modification process 0.0129488757072583 4041 62 24 0.387096774193548 0.00593912397921307
GO:BP GO:0036211 protein modification process 0.0129488757072583 4041 62 24 0.387096774193548 0.00593912397921307
GO:BP GO:0045860 positive regulation of protein kinase activity 0.0131140296223501 534 33 5 0.151515151515152 0.00936329588014981
GO:BP GO:0050794 regulation of cellular process 0.0131260961708408 11473 13 13 1 0.00113309509282664
GO:BP GO:0023052 signaling 0.0131324969930948 6810 16 12 0.75 0.00176211453744493
GO:BP GO:0097659 nucleic acid-templated transcription 0.0131324969930948 3715 67 24 0.358208955223881 0.00646029609690444
GO:BP GO:1901214 regulation of neuron death 0.0131324969930948 323 16 3 0.1875 0.00928792569659443
GO:BP GO:0022409 positive regulation of cell-cell adhesion 0.0131375467319909 284 61 5 0.0819672131147541 0.0176056338028169
GO:BP GO:0006355 regulation of transcription, DNA-templated 0.0131977526074106 3534 9 6 0.666666666666667 0.00169779286926995
GO:BP GO:0051346 negative regulation of hydrolase activity 0.0132216115323307 470 92 8 0.0869565217391304 0.0170212765957447
GO:BP GO:0007154 cell communication 0.0134124194527255 6829 16 12 0.75 0.00175721189046713
GO:BP GO:0006793 phosphorus metabolic process 0.0135972153322718 3114 62 20 0.32258064516129 0.00642260757867694
GO:BP GO:0032774 RNA biosynthetic process 0.0137157278847938 3731 67 24 0.358208955223881 0.00643259179844546
GO:BP GO:0032872 regulation of stress-activated MAPK cascade 0.013765933387745 190 56 4 0.0714285714285714 0.0210526315789474
GO:BP GO:0032147 activation of protein kinase activity 0.0142973709106374 331 33 4 0.121212121212121 0.0120845921450151
GO:BP GO:0070302 regulation of stress-activated protein kinase signaling cascade 0.014414979216249 193 56 4 0.0714285714285714 0.0207253886010363
GO:BP GO:0090304 nucleic acid metabolic process 0.0144260145357164 5226 13 9 0.692307692307692 0.00172215843857635
GO:BP GO:1903322 positive regulation of protein modification by small protein conjugation or removal 0.0144260145357164 140 77 4 0.051948051948052 0.0285714285714286
GO:BP GO:0009056 catabolic process 0.014480173503089 2744 34 12 0.352941176470588 0.0043731778425656
GO:BP GO:0097300 programmed necrotic cell death 0.0145703099556589 54 97 3 0.0309278350515464 0.0555555555555556
GO:BP GO:1903747 regulation of establishment of protein localization to mitochondrion 0.0150770816012925 72 74 3 0.0405405405405405 0.0416666666666667
GO:BP GO:1902904 negative regulation of supramolecular fiber organization 0.0152885196208933 170 106 5 0.0471698113207547 0.0294117647058824
GO:BP GO:0033036 macromolecule localization 0.0153138429274449 3218 16 8 0.5 0.00248601615910503
GO:BP GO:0034641 cellular nitrogen compound metabolic process 0.0157832973171925 6563 13 10 0.769230769230769 0.0015236934328813
GO:BP GO:0070227 lymphocyte apoptotic process 0.0161161821775925 74 74 3 0.0405405405405405 0.0405405405405405
GO:BP GO:0006351 transcription, DNA-templated 0.0161933659875021 3714 9 6 0.666666666666667 0.00161550888529887
GO:BP GO:0010647 positive regulation of cell communication 0.0161933659875021 1777 4 3 0.75 0.00168823860438942
GO:BP GO:0006508 proteolysis 0.0162268438980315 1836 16 6 0.375 0.00326797385620915
GO:BP GO:0008152 metabolic process 0.0162268438980315 11827 37 32 0.864864864864865 0.00270567345903441
GO:BP GO:0051094 positive regulation of developmental process 0.0162291792838079 1341 15 5 0.333333333333333 0.00372856077554064
GO:BP GO:0023056 positive regulation of signaling 0.0162291792838079 1782 4 3 0.75 0.00168350168350168
GO:BP GO:0008277 regulation of G protein-coupled receptor signaling pathway 0.0168544541099983 149 38 3 0.0789473684210526 0.0201342281879195
GO:BP GO:0070997 neuron death 0.0168843402730288 365 16 3 0.1875 0.00821917808219178
GO:BP GO:0022407 regulation of cell-cell adhesion 0.0169742575176319 445 61 6 0.0983606557377049 0.0134831460674157
GO:BP GO:0043542 endothelial cell migration 0.0169800290035482 290 20 3 0.15 0.0103448275862069
GO:BP GO:0001666 response to hypoxia 0.0169934889655937 367 16 3 0.1875 0.00817438692098093
GO:BP GO:0072359 circulatory system development 0.0173597128621506 1194 17 5 0.294117647058824 0.00418760469011725
GO:BP GO:0033674 positive regulation of kinase activity 0.0183356412898692 608 61 7 0.114754098360656 0.0115131578947368
GO:BP GO:0036293 response to decreased oxygen levels 0.0184686799935616 382 16 3 0.1875 0.00785340314136126
GO:BP GO:0007275 multicellular organism development 0.0185343770371724 5613 17 11 0.647058823529412 0.00195973632638518
GO:BP GO:0048545 response to steroid hormone 0.0189281329461803 349 56 5 0.0892857142857143 0.0143266475644699
GO:BP GO:0010632 regulation of epithelial cell migration 0.0189281329461803 306 20 3 0.15 0.00980392156862745
GO:BP GO:0061448 connective tissue development 0.0194016901439677 256 24 3 0.125 0.01171875
GO:BP GO:0034976 response to endoplasmic reticulum stress 0.0195563226728846 298 94 6 0.0638297872340425 0.0201342281879195
GO:BP GO:0033138 positive regulation of peptidyl-serine phosphorylation 0.0197785387815576 109 56 3 0.0535714285714286 0.0275229357798165
GO:BP GO:0031401 positive regulation of protein modification process 0.0199084311355974 1074 97 13 0.134020618556701 0.0121042830540037
GO:BP GO:0061919 process utilizing autophagic mechanism 0.0202895896830772 543 12 3 0.25 0.00552486187845304
GO:BP GO:0006914 autophagy 0.0202895896830772 543 12 3 0.25 0.00552486187845304
GO:BP GO:0032879 regulation of localization 0.0207078602222931 2872 15 7 0.466666666666667 0.00243732590529248
GO:BP GO:0070482 response to oxygen levels 0.0211368976718252 408 16 3 0.1875 0.00735294117647059
GO:BP GO:0006139 nucleobase-containing compound metabolic process 0.0212755014714007 5746 7 6 0.857142857142857 0.00104420466411417
GO:BP GO:0009891 positive regulation of biosynthetic process 0.0212755014714007 2004 92 19 0.206521739130435 0.0094810379241517
GO:BP GO:0010557 positive regulation of macromolecule biosynthetic process 0.0212755014714007 1851 17 6 0.352941176470588 0.00324149108589951
GO:BP GO:0050789 regulation of biological process 0.0213260696487574 12091 13 13 1 0.00107517988586552
GO:BP GO:0032103 positive regulation of response to external stimulus 0.0213925321150391 513 13 3 0.230769230769231 0.00584795321637427
GO:BP GO:0043412 macromolecule modification 0.0214922118895547 4257 62 24 0.387096774193548 0.00563777307963354
GO:BP GO:0000165 MAPK cascade 0.0215142119824358 935 42 7 0.166666666666667 0.00748663101604278
GO:BP GO:0071495 cellular response to endogenous stimulus 0.0219443202948142 1422 10 4 0.4 0.00281293952180028
GO:BP GO:0050863 regulation of T cell activation 0.022242491280273 337 61 5 0.0819672131147541 0.0148367952522255
GO:BP GO:0030316 osteoclast differentiation 0.022242491280273 98 66 3 0.0454545454545455 0.0306122448979592
GO:BP GO:0006807 nitrogen compound metabolic process 0.0223577951227391 10078 13 12 0.923076923076923 0.00119071244294503
GO:BP GO:0002684 positive regulation of immune system process 0.0223577951227391 1065 13 4 0.307692307692308 0.00375586854460094
GO:BP GO:0070265 necrotic cell death 0.0231832546123973 68 97 3 0.0309278350515464 0.0441176470588235
GO:BP GO:1990542 mitochondrial transmembrane transport 0.0232525749349223 114 58 3 0.0517241379310345 0.0263157894736842
GO:BP GO:0046483 heterocycle metabolic process 0.0239048939803848 5904 7 6 0.857142857142857 0.00101626016260163
GO:BP GO:0030834 regulation of actin filament depolymerization 0.0240162283641632 57 118 3 0.0254237288135593 0.0526315789473684
GO:BP GO:0009612 response to mechanical stimulus 0.0241162805088959 218 61 4 0.0655737704918033 0.018348623853211
GO:BP GO:0032874 positive regulation of stress-activated MAPK cascade 0.0241162805088959 121 56 3 0.0535714285714286 0.0247933884297521
GO:BP GO:0050870 positive regulation of T cell activation 0.0244475930677663 219 61 4 0.0655737704918033 0.0182648401826484
GO:BP GO:0006725 cellular aromatic compound metabolic process 0.0244475930677663 5956 7 6 0.857142857142857 0.0010073875083949
GO:BP GO:0098656 anion transmembrane transport 0.0244475930677663 550 13 3 0.230769230769231 0.00545454545454545
GO:BP GO:0033993 response to lipid 0.0248690381532009 918 67 9 0.134328358208955 0.00980392156862745
GO:BP GO:0070304 positive regulation of stress-activated protein kinase signaling cascade 0.0250571022641639 123 56 3 0.0535714285714286 0.024390243902439
GO:BP GO:0032501 multicellular organismal process 0.0253493124998862 7946 17 13 0.764705882352941 0.0016360432922225
GO:BP GO:0065007 biological regulation 0.0254558620718276 12809 21 20 0.952380952380952 0.00156140213912093
GO:BP GO:0051254 positive regulation of RNA metabolic process 0.0258780304298057 1714 9 4 0.444444444444444 0.00233372228704784
GO:BP GO:0007264 small GTPase mediated signal transduction 0.0260881275024519 515 119 9 0.0756302521008403 0.0174757281553398
GO:BP GO:0016070 RNA metabolic process 0.0272215417655669 4710 13 8 0.615384615384615 0.00169851380042463
GO:BP GO:0010631 epithelial cell migration 0.0277747823712854 370 20 3 0.15 0.00810810810810811
GO:BP GO:1901216 positive regulation of neuron death 0.0281002716804015 98 74 3 0.0405405405405405 0.0306122448979592
GO:BP GO:0002573 myeloid leukocyte differentiation 0.0282324631627596 213 66 4 0.0606060606060606 0.0187793427230047
GO:BP GO:0090132 epithelium migration 0.0282584358086684 373 20 3 0.15 0.00804289544235925
GO:BP GO:0065004 protein-DNA complex assembly 0.0285097216773948 252 88 5 0.0568181818181818 0.0198412698412698
GO:BP GO:0030042 actin filament depolymerization 0.0285153043253746 62 118 3 0.0254237288135593 0.0483870967741935
GO:BP GO:0090130 tissue migration 0.0290948308090671 379 20 3 0.15 0.0079155672823219
GO:BP GO:1901360 organic cyclic compound metabolic process 0.0290948308090671 6201 7 6 0.857142857142857 0.000967585873246251
GO:BP GO:0032675 regulation of interleukin-6 production 0.0294302496255033 168 85 4 0.0470588235294118 0.0238095238095238
GO:BP GO:0014070 response to organic cyclic compound 0.0297768685762539 967 44 7 0.159090909090909 0.00723888314374354
GO:BP GO:0030865 cortical cytoskeleton organization 0.0298466728212624 63 119 3 0.0252100840336134 0.0476190476190476
GO:BP GO:0032496 response to lipopolysaccharide 0.0298466728212624 338 67 5 0.0746268656716418 0.014792899408284
GO:BP GO:0048513 animal organ development 0.030092145258074 3672 3 3 1 0.000816993464052288
GO:BP GO:0016043 cellular component organization 0.0301475779874481 6566 16 11 0.6875 0.00167529698446543
GO:BP GO:0007266 Rho protein signal transduction 0.0301842530761367 136 106 4 0.0377358490566038 0.0294117647058824
GO:BP GO:0048856 anatomical structure development 0.030491640632518 6106 37 20 0.540540540540541 0.00327546675401245
GO:BP GO:0034766 negative regulation of ion transmembrane transport 0.0307379075289156 131 111 4 0.036036036036036 0.0305343511450382
GO:BP GO:0006259 DNA metabolic process 0.0309884408863176 965 16 4 0.25 0.00414507772020725
GO:BP GO:0034763 negative regulation of transmembrane transport 0.0312379613929037 132 111 4 0.036036036036036 0.0303030303030303
GO:BP GO:0044238 primary metabolic process 0.0313577682879442 10584 37 29 0.783783783783784 0.00273998488284203
GO:BP GO:1903557 positive regulation of tumor necrosis factor superfamily cytokine production 0.0315286871656887 91 85 3 0.0352941176470588 0.032967032967033
GO:BP GO:0007015 actin filament organization 0.0318771474657357 445 119 8 0.0672268907563025 0.0179775280898876
GO:BP GO:0030154 cell differentiation 0.0323769550654523 4350 17 9 0.529411764705882 0.00206896551724138
GO:BP GO:0031328 positive regulation of cellular biosynthetic process 0.0323769550654523 1967 92 18 0.195652173913043 0.00915099135739705
GO:BP GO:0006417 regulation of translation 0.034035099614718 462 18 3 0.166666666666667 0.00649350649350649
GO:BP GO:0071677 positive regulation of mononuclear cell migration 0.0342959745797463 65 125 3 0.024 0.0461538461538462
GO:BP GO:0033135 regulation of peptidyl-serine phosphorylation 0.0346533207781541 146 56 3 0.0535714285714286 0.0205479452054795
GO:BP GO:0048869 cellular developmental process 0.035039919025983 4428 17 9 0.529411764705882 0.00203252032520325
GO:BP GO:0040013 negative regulation of locomotion 0.035179135010244 401 21 3 0.142857142857143 0.00748129675810474
GO:BP GO:0071840 cellular component organization or biogenesis 0.0352736261547821 6760 16 11 0.6875 0.00162721893491124
GO:BP GO:0002237 response to molecule of bacterial origin 0.0354006226234593 361 67 5 0.0746268656716418 0.0138504155124654
GO:BP GO:0007265 Ras protein signal transduction 0.0355298928098623 349 45 4 0.0888888888888889 0.0114613180515759
GO:BP GO:0006665 sphingolipid metabolic process 0.0355298928098623 169 92 4 0.0434782608695652 0.0236686390532544
GO:BP GO:0007417 central nervous system development 0.0357857982290634 1032 16 4 0.25 0.00387596899224806
GO:BP GO:0071706 tumor necrosis factor superfamily cytokine production 0.0358634090840567 170 92 4 0.0434782608695652 0.0235294117647059
GO:BP GO:0055085 transmembrane transport 0.0362084924567284 1635 16 5 0.3125 0.00305810397553517
GO:BP GO:0043506 regulation of JUN kinase activity 0.0368694172700779 87 97 3 0.0309278350515464 0.0344827586206897
GO:BP GO:0032880 regulation of protein localization 0.0384990344580529 922 10 3 0.3 0.00325379609544469
GO:BP GO:0042327 positive regulation of phosphorylation 0.0386222329575871 927 61 8 0.131147540983607 0.00862998921251348
GO:BP GO:0002367 cytokine production involved in immune response 0.0387245278227046 94 92 3 0.0326086956521739 0.0319148936170213
GO:BP GO:0044237 cellular metabolic process 0.039765920188784 10871 13 12 0.923076923076923 0.00110385429123356
GO:BP GO:0048232 male gamete generation 0.040211072607314 570 16 3 0.1875 0.00526315789473684
GO:BP GO:0071396 cellular response to lipid 0.0406049575520267 578 61 6 0.0983606557377049 0.0103806228373702
GO:BP GO:0001525 angiogenesis 0.0411601061507899 617 15 3 0.2 0.00486223662884927
GO:BP GO:0009615 response to virus 0.0420319866346572 364 97 6 0.0618556701030928 0.0164835164835165
GO:BP GO:0050793 regulation of developmental process 0.0424554449650102 2605 15 6 0.4 0.00230326295585413
GO:BP GO:0071824 protein-DNA complex subunit organization 0.0436448656110229 294 88 5 0.0568181818181818 0.0170068027210884
GO:BP GO:0071383 cellular response to steroid hormone stimulus 0.0437704583019015 210 44 3 0.0681818181818182 0.0142857142857143
GO:BP GO:0001934 positive regulation of protein phosphorylation 0.0439286216137833 840 56 7 0.125 0.00833333333333333
GO:BP GO:0031960 response to corticosteroid 0.0439636845446751 165 56 3 0.0535714285714286 0.0181818181818182
GO:BP GO:0044070 regulation of anion transport 0.0447209309901097 896 11 3 0.272727272727273 0.00334821428571429
GO:BP GO:0034248 regulation of cellular amide metabolic process 0.0453631841809226 535 18 3 0.166666666666667 0.00560747663551402
GO:BP GO:0048871 multicellular organismal homeostasis 0.0453837789788902 530 33 4 0.121212121212121 0.00754716981132075
GO:BP GO:0006996 organelle organization 0.0453837789788902 4104 16 8 0.5 0.00194931773879142
GO:BP GO:0051704 multi-organism process 0.0454658812666113 1135 16 4 0.25 0.00352422907488987
GO:BP GO:0002440 production of molecular mediator of immune response 0.0464622425536146 189 92 4 0.0434782608695652 0.0211640211640212
GO:BP GO:0035295 tube development 0.0464622425536146 1146 16 4 0.25 0.00349040139616056
GO:BP GO:0045785 positive regulation of cell adhesion 0.0464622425536146 437 61 5 0.0819672131147541 0.011441647597254
GO:BP GO:0006672 ceramide metabolic process 0.0470349351779103 104 92 3 0.0326086956521739 0.0288461538461538
GO:BP GO:0043410 positive regulation of MAPK cascade 0.0471265385317269 539 33 4 0.121212121212121 0.00742115027829314
GO:BP GO:0010243 response to organonitrogen compound 0.047694412455588 1085 17 4 0.235294117647059 0.00368663594470046
GO:BP GO:0001667 ameboidal-type cell migration 0.047694412455588 494 20 3 0.15 0.00607287449392713
GO:BP GO:0051494 negative regulation of cytoskeleton organization 0.0479388347678151 166 106 4 0.0377358490566038 0.0240963855421687
GO:BP GO:0006260 DNA replication 0.0482051813227994 286 62 4 0.0645161290322581 0.013986013986014
GO:BP GO:0001659 temperature homeostasis 0.0483313974857613 174 56 3 0.0535714285714286 0.0172413793103448
GO:BP GO:0045834 positive regulation of lipid metabolic process 0.0493372995516856 155 115 4 0.0347826086956522 0.0258064516129032
GO:CC GO:0070062 extracellular exosome 1.75879559678012e-10 2176 17 15 0.882352941176471 0.00689338235294118
GO:CC GO:1903561 extracellular vesicle 1.75879559678012e-10 2261 17 15 0.882352941176471 0.00663423264042459
GO:CC GO:0043230 extracellular organelle 1.75879559678012e-10 2263 17 15 0.882352941176471 0.0066283694211224
GO:CC GO:0005829 cytosol 3.96667394775065e-08 5303 20 19 0.95 0.00358287761644352
GO:CC GO:0005615 extracellular space 9.49353527889984e-08 3594 17 15 0.882352941176471 0.00417362270450751
GO:CC GO:0031982 vesicle 4.58660876320634e-07 4055 17 15 0.882352941176471 0.00369913686806412
GO:CC GO:1904813 ficolin-1-rich granule lumen 1.0835908886973e-06 124 14 5 0.357142857142857 0.0403225806451613
GO:CC GO:0005576 extracellular region 1.92532756372683e-06 4567 17 15 0.882352941176471 0.00328443179329976
GO:CC GO:0101002 ficolin-1-rich granule 5.07378069745708e-06 184 6 4 0.666666666666667 0.0217391304347826
GO:CC GO:0005737 cytoplasm 8.4782592183481e-06 11911 51 48 0.941176470588235 0.00402988833851062
GO:CC GO:0005739 mitochondrion 6.20564058875018e-05 1673 16 9 0.5625 0.00537955768081291
GO:CC GO:0008180 COP9 signalosome 6.20564058875018e-05 35 14 3 0.214285714285714 0.0857142857142857
GO:CC GO:0072562 blood microparticle 7.45321254586967e-05 140 14 4 0.285714285714286 0.0285714285714286
GO:CC GO:0097708 intracellular vesicle 0.00010055750830961 2428 16 10 0.625 0.00411861614497529
GO:CC GO:0031410 cytoplasmic vesicle 0.00010055750830961 2424 16 10 0.625 0.00412541254125413
GO:CC GO:0043233 organelle lumen 0.000181922094286961 5565 17 14 0.823529411764706 0.00251572327044025
GO:CC GO:0031974 membrane-enclosed lumen 0.000181922094286961 5565 17 14 0.823529411764706 0.00251572327044025
GO:CC GO:0070013 intracellular organelle lumen 0.000233305034564335 5402 9 9 1 0.00166604961125509
GO:CC GO:0005925 focal adhesion 0.000234392713008892 420 15 5 0.333333333333333 0.0119047619047619
GO:CC GO:0030055 cell-substrate junction 0.000241803947544948 427 15 5 0.333333333333333 0.0117096018735363
GO:CC GO:0030141 secretory granule 0.000276926879616232 851 14 6 0.428571428571429 0.00705052878965922
GO:CC GO:0048471 perinuclear region of cytoplasm 0.000277551021540306 735 10 5 0.5 0.00680272108843537
GO:CC GO:0101031 chaperone complex 0.000353745749171595 27 40 3 0.075 0.111111111111111
GO:CC GO:0005654 nucleoplasm 0.000462931875823869 4102 9 8 0.888888888888889 0.00195026816187226
GO:CC GO:0099503 secretory vesicle 0.000634890631371138 1020 14 6 0.428571428571429 0.00588235294117647
GO:CC GO:0005634 nucleus 0.000690736540151198 7592 17 15 0.882352941176471 0.00197576396206533
GO:CC GO:0031981 nuclear lumen 0.000750353871337166 4444 9 8 0.888888888888889 0.0018001800180018
GO:CC GO:0043231 intracellular membrane-bounded organelle 0.00108985376491233 11296 28 26 0.928571428571429 0.00230169971671388
GO:CC GO:0030139 endocytic vesicle 0.00113322681042075 306 16 4 0.25 0.0130718954248366
GO:CC GO:0043005 neuron projection 0.00114512148709555 1380 17 7 0.411764705882353 0.00507246376811594
GO:CC GO:0015630 microtubule cytoskeleton 0.00202336093211751 1307 14 6 0.428571428571429 0.00459066564651875
GO:CC GO:0043202 lysosomal lumen 0.00213422623142161 97 23 3 0.130434782608696 0.0309278350515464
GO:CC GO:0005886 plasma membrane 0.00253798880951941 5681 16 12 0.75 0.00211230417180074
GO:CC GO:0070161 anchoring junction 0.00316750987719859 836 15 5 0.333333333333333 0.00598086124401914
GO:CC GO:0071944 cell periphery 0.00316750987719859 6169 38 23 0.605263157894737 0.00372831901442697
GO:CC GO:0043232 intracellular non-membrane-bounded organelle 0.00316750987719859 5338 15 11 0.733333333333333 0.00206069689022106
GO:CC GO:0005622 intracellular anatomical structure 0.00316750987719859 14790 51 49 0.96078431372549 0.0033130493576741
GO:CC GO:0043228 non-membrane-bounded organelle 0.00316750987719859 5346 15 11 0.733333333333333 0.00205761316872428
GO:CC GO:0012505 endomembrane system 0.00317976004752667 4640 29 16 0.551724137931034 0.00344827586206897
GO:CC GO:0042995 cell projection 0.00351483697251682 2330 17 8 0.470588235294118 0.00343347639484979
GO:CC GO:0043229 intracellular organelle 0.00362236627431967 12491 30 28 0.933333333333333 0.00224161396205268
GO:CC GO:0034774 secretory granule lumen 0.00393984089851487 320 23 4 0.173913043478261 0.0125
GO:CC GO:0005768 endosome 0.00393984089851487 987 21 6 0.285714285714286 0.0060790273556231
GO:CC GO:0140513 nuclear protein-containing complex 0.00394084507768745 1249 7 4 0.571428571428571 0.00320256204963971
GO:CC GO:0060205 cytoplasmic vesicle lumen 0.00396943998271118 324 23 4 0.173913043478261 0.0123456790123457
GO:CC GO:0031983 vesicle lumen 0.00398563942786465 326 23 4 0.173913043478261 0.0122699386503067
GO:CC GO:0030425 dendrite 0.00456037601126777 638 6 3 0.5 0.00470219435736677
GO:CC GO:0097447 dendritic tree 0.00456037601126777 640 6 3 0.5 0.0046875
GO:CC GO:1990904 ribonucleoprotein complex 0.00553541519089836 688 6 3 0.5 0.00436046511627907
GO:CC GO:0005856 cytoskeleton 0.00673182133112226 2332 15 7 0.466666666666667 0.00300171526586621
GO:CC GO:0005775 vacuolar lumen 0.00705211016942707 174 23 3 0.130434782608696 0.0172413793103448
GO:CC GO:0030054 cell junction 0.00793599967031772 2105 3 3 1 0.00142517814726841
GO:CC GO:0043227 membrane-bounded organelle 0.00793599967031772 12858 17 17 1 0.00132213407995023
GO:CC GO:0044297 cell body 0.00910718976313096 592 17 4 0.235294117647059 0.00675675675675676
GO:CC GO:0036477 somatodendritic compartment 0.00964072706135101 871 6 3 0.5 0.0034443168771527
GO:CC GO:0120025 plasma membrane bounded cell projection 0.0103828367671304 2229 17 7 0.411764705882353 0.00314042171377299
GO:CC GO:0000323 lytic vacuole 0.0116211898938864 712 92 10 0.108695652173913 0.0140449438202247
GO:CC GO:0005764 lysosome 0.0116211898938864 712 92 10 0.108695652173913 0.0140449438202247
GO:CC GO:0016020 membrane 0.0149257021762879 9838 16 14 0.875 0.00142305346615166
GO:CC GO:0005783 endoplasmic reticulum 0.0173999920041004 1982 16 6 0.375 0.00302724520686176
GO:CC GO:0098552 side of membrane 0.019433984281902 619 11 3 0.272727272727273 0.00484652665589661
GO:CC GO:0032991 protein-containing complex 0.0198210357095522 5548 18 11 0.611111111111111 0.00198269646719539
GO:CC GO:0005773 vacuole 0.0224132096069195 810 92 10 0.108695652173913 0.0123456790123457
GO:CC GO:0043226 organelle 0.0224132096069195 14008 17 17 1 0.00121359223300971
GO:CC GO:0030424 axon 0.0265517254176874 660 12 3 0.25 0.00454545454545455
GO:CC GO:0005769 early endosome 0.0285457131738472 378 21 3 0.142857142857143 0.00793650793650794
GO:CC GO:0010008 endosome membrane 0.0286674752885939 505 16 3 0.1875 0.00594059405940594
GO:CC GO:0005730 nucleolus 0.0301571946327927 955 83 10 0.120481927710843 0.0104712041884817
GO:CC GO:0098852 lytic vacuole membrane 0.0352352984217888 383 92 6 0.0652173913043478 0.0156657963446475
GO:CC GO:0005765 lysosomal membrane 0.0352352984217888 383 92 6 0.0652173913043478 0.0156657963446475
GO:MF GO:0051082 unfolded protein binding 1.13270019882823e-18 112 24 12 0.5 0.107142857142857
GO:MF GO:0044183 protein folding chaperone 1.8826626006755e-14 35 14 7 0.5 0.2
GO:MF GO:0031625 ubiquitin protein ligase binding 1.8826626006755e-14 296 17 11 0.647058823529412 0.0371621621621622
GO:MF GO:0044389 ubiquitin-like protein ligase binding 2.71800172548566e-14 314 17 11 0.647058823529412 0.035031847133758
GO:MF GO:0031072 heat shock protein binding 5.98488687547055e-12 127 39 10 0.256410256410256 0.078740157480315
GO:MF GO:0051087 chaperone binding 1.67544835095266e-11 103 53 10 0.188679245283019 0.0970873786407767
GO:MF GO:0055131 C3HC4-type RING finger domain binding 3.34615348768884e-11 6 10 4 0.4 0.666666666666667
GO:MF GO:0060590 ATPase regulator activity 4.25918608614256e-10 44 77 8 0.103896103896104 0.181818181818182
GO:MF GO:0019899 enzyme binding 8.57798916569373e-10 2074 17 14 0.823529411764706 0.00675024108003857
GO:MF GO:0051787 misfolded protein binding 1.50919920500861e-07 28 14 4 0.285714285714286 0.142857142857143
GO:MF GO:0017111 nucleoside-triphosphatase activity 1.15309112986067e-06 872 18 9 0.5 0.0103211009174312
GO:MF GO:0016818 hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides 1.32547248429206e-06 930 18 9 0.5 0.00967741935483871
GO:MF GO:0016462 pyrophosphatase activity 1.32547248429206e-06 928 18 9 0.5 0.00969827586206897
GO:MF GO:0030554 adenyl nucleotide binding 1.32547248429206e-06 1578 31 14 0.451612903225806 0.00887198986058302
GO:MF GO:0016817 hydrolase activity, acting on acid anhydrides 1.32547248429206e-06 930 18 9 0.5 0.00967741935483871
GO:MF GO:0035639 purine ribonucleoside triphosphate binding 1.32547248429206e-06 1847 20 12 0.6 0.00649702219815918
GO:MF GO:0001671 ATPase activator activity 1.32547248429206e-06 25 77 5 0.0649350649350649 0.2
GO:MF GO:0032555 purine ribonucleotide binding 1.43768150276865e-06 1918 20 12 0.6 0.00625651720542232
GO:MF GO:0005524 ATP binding 1.43768150276865e-06 1501 20 11 0.55 0.00732844770153231
GO:MF GO:0017076 purine nucleotide binding 1.43768150276865e-06 1933 47 19 0.404255319148936 0.00982928091050181
GO:MF GO:0032553 ribonucleotide binding 1.51141052699525e-06 1935 20 12 0.6 0.0062015503875969
GO:MF GO:0032559 adenyl ribonucleotide binding 1.95452425068737e-06 1565 20 11 0.55 0.00702875399361022
GO:MF GO:0016887 ATPase activity 3.23804690619642e-06 488 18 7 0.388888888888889 0.014344262295082
GO:MF GO:1901265 nucleoside phosphate binding 4.59588105624105e-06 2172 20 12 0.6 0.00552486187845304
GO:MF GO:0000166 nucleotide binding 4.59588105624105e-06 2171 20 12 0.6 0.00552740672501152
GO:MF GO:0019904 protein domain specific binding 7.60634585644439e-06 710 10 6 0.6 0.00845070422535211
GO:MF GO:0097367 carbohydrate derivative binding 7.60634585644439e-06 2285 20 12 0.6 0.00525164113785558
GO:MF GO:0003723 RNA binding 9.14528425216245e-06 1943 13 9 0.692307692307692 0.00463201235203294
GO:MF GO:0030234 enzyme regulator activity 1.02113608007348e-05 1248 39 13 0.333333333333333 0.0104166666666667
GO:MF GO:0036094 small molecule binding 1.07090280175502e-05 2506 47 20 0.425531914893617 0.00798084596967279
GO:MF GO:0042826 histone deacetylase binding 1.13068832021765e-05 116 4 3 0.75 0.0258620689655172
GO:MF GO:0043168 anion binding 1.1703099809021e-05 2418 20 12 0.6 0.00496277915632754
GO:MF GO:0060589 nucleoside-triphosphatase regulator activity 1.26392712913804e-05 530 39 9 0.230769230769231 0.0169811320754717
GO:MF GO:0001664 G protein-coupled receptor binding 0.000125735674512524 292 10 4 0.4 0.0136986301369863
GO:MF GO:0098772 molecular function regulator 0.000193517060592694 2363 12 8 0.666666666666667 0.00338552687261955
GO:MF GO:1901363 heterocyclic compound binding 0.000288449241288548 6228 15 13 0.866666666666667 0.00208734746307001
GO:MF GO:0097159 organic cyclic compound binding 0.000321620904459941 6309 15 13 0.866666666666667 0.00206054842288794
GO:MF GO:0061629 RNA polymerase II-specific DNA-binding transcription factor binding 0.000534012358487921 281 67 7 0.104477611940299 0.0249110320284698
GO:MF GO:0008047 enzyme activator activity 0.000860861228504543 540 39 7 0.179487179487179 0.012962962962963
GO:MF GO:0045296 cadherin binding 0.000860861228504543 333 6 3 0.5 0.00900900900900901
GO:MF GO:0005515 protein binding 0.000860861228504543 14767 50 49 0.98 0.00331820952122977
GO:MF GO:0016787 hydrolase activity 0.00212781989989501 2615 18 9 0.5 0.00344168260038241
GO:MF GO:0050839 cell adhesion molecule binding 0.00318953316101297 546 6 3 0.5 0.00549450549450549
GO:MF GO:0140297 DNA-binding transcription factor binding 0.00326251441202594 391 67 7 0.104477611940299 0.0179028132992327
GO:MF GO:0003676 nucleic acid binding 0.00326251441202594 4276 13 9 0.692307692307692 0.00210477081384471
GO:MF GO:0002020 protease binding 0.00598725894666725 133 61 4 0.0655737704918033 0.0300751879699248
GO:MF GO:0003924 GTPase activity 0.00744899734147118 328 119 8 0.0672268907563025 0.024390243902439
GO:MF GO:0005516 calmodulin binding 0.00839623426642787 204 111 6 0.0540540540540541 0.0294117647058824
GO:MF GO:0005246 calcium channel regulator activity 0.0132114476406627 45 111 3 0.027027027027027 0.0666666666666667
GO:MF GO:0008134 transcription factor binding 0.0151103704609417 676 67 8 0.119402985074627 0.0118343195266272
GO:MF GO:0015631 tubulin binding 0.0215565537042973 376 17 3 0.176470588235294 0.00797872340425532
GO:MF GO:0043167 ion binding 0.0279374740194985 6057 15 10 0.666666666666667 0.00165098233448902
GO:MF GO:0035591 signaling adaptor activity 0.0296209723825318 70 106 3 0.0283018867924528 0.0428571428571429
GO:MF GO:0008092 cytoskeletal protein binding 0.0324958208818283 996 34 6 0.176470588235294 0.00602409638554217
GO:MF GO:0043130 ubiquitin binding 0.0330597627825259 83 96 3 0.03125 0.036144578313253
GO:MF GO:0044877 protein-containing complex binding 0.0330597627825259 1287 7 3 0.428571428571429 0.00233100233100233
GO:MF GO:0051020 GTPase binding 0.037844977241404 330 106 6 0.0566037735849057 0.0181818181818182
GO:MF GO:0032182 ubiquitin-like protein binding 0.0449242955714382 100 96 3 0.03125 0.03
GO:MF GO:0019901 protein kinase binding 0.0458773790026732 673 15 3 0.2 0.00445765230312036
GO:MF GO:0035257 nuclear hormone receptor binding 0.0471824660614651 148 67 3 0.0447761194029851 0.0202702702702703
HPA HPA:0110223 cervix, uterine; squamous epithelial cells[High] 0.0183103066815011 986 10 6 0.6 0.00608519269776876
HPA HPA:0470683 skin 2; epidermal cells[High] 0.0183103066815011 1346 17 9 0.529411764705882 0.00668647845468053
HPA HPA:0190223 esophagus; squamous epithelial cells[High] 0.0367590020227379 1596 17 9 0.529411764705882 0.0056390977443609
HPA HPA:0570763 testis; pachytene spermatocytes[High] 0.0458306439158249 822 3 3 1 0.00364963503649635
KEGG KEGG:04141 Protein processing in endoplasmic reticulum 1.57636084355623e-08 170 14 8 0.571428571428571 0.0470588235294118
KEGG KEGG:04915 Estrogen signaling pathway 1.54720230096412e-06 137 7 5 0.714285714285714 0.0364963503649635
KEGG KEGG:05134 Legionellosis 1.54720230096412e-06 57 27 6 0.222222222222222 0.105263157894737
KEGG KEGG:04612 Antigen processing and presentation 3.11314130670637e-06 69 6 4 0.666666666666667 0.0579710144927536
KEGG KEGG:05162 Measles 8.54296096397833e-05 139 14 5 0.357142857142857 0.0359712230215827
KEGG KEGG:04213 Longevity regulating pathway - multiple species 8.54296096397833e-05 62 14 4 0.285714285714286 0.0645161290322581
KEGG KEGG:04010 MAPK signaling pathway 0.000129882990083213 294 14 6 0.428571428571429 0.0204081632653061
KEGG KEGG:05145 Toxoplasmosis 0.000609469941379969 109 14 4 0.285714285714286 0.036697247706422
KEGG KEGG:03040 Spliceosome 0.00189302734903603 150 14 4 0.285714285714286 0.0266666666666667
KEGG KEGG:04137 Mitophagy - animal 0.00504313269409632 68 16 3 0.1875 0.0441176470588235
KEGG KEGG:04144 Endocytosis 0.00868467914843444 252 6 3 0.5 0.0119047619047619
KEGG KEGG:05020 Prion disease 0.0100700314430167 273 6 3 0.5 0.010989010989011
KEGG KEGG:04064 NF-kappa B signaling pathway 0.0131663924593067 102 61 5 0.0819672131147541 0.0490196078431373
MIRNA MIRNA:hsa-miR-365b-3p hsa-miR-365b-3p 0.000341204455561865 86 45 6 0.133333333333333 0.0697674418604651
MIRNA MIRNA:hsa-miR-16-5p hsa-miR-16-5p 0.000421447060086291 1556 10 8 0.8 0.0051413881748072
MIRNA MIRNA:hsa-miR-365a-3p hsa-miR-365a-3p 0.000945531248402871 123 45 6 0.133333333333333 0.0487804878048781
MIRNA MIRNA:hsa-miR-10a-5p hsa-miR-10a-5p 0.00502198115547146 461 6 4 0.666666666666667 0.00867678958785249
MIRNA MIRNA:hsa-miR-221-3p hsa-miR-221-3p 0.00502198115547146 366 34 7 0.205882352941176 0.0191256830601093
MIRNA MIRNA:hsa-miR-324-3p hsa-miR-324-3p 0.0078317152421542 336 9 4 0.444444444444444 0.0119047619047619
MIRNA MIRNA:hsa-miR-15a-5p hsa-miR-15a-5p 0.00969278147002381 717 10 5 0.5 0.00697350069735007
MIRNA MIRNA:hsa-miR-378a-3p hsa-miR-378a-3p 0.00969278147002381 165 88 7 0.0795454545454545 0.0424242424242424
MIRNA MIRNA:hsa-miR-7-2-3p hsa-miR-7-2-3p 0.00969278147002381 167 19 4 0.210526315789474 0.0239520958083832
MIRNA MIRNA:hsa-miR-7-1-3p hsa-miR-7-1-3p 0.0111213848843339 180 19 4 0.210526315789474 0.0222222222222222
MIRNA MIRNA:hsa-miR-30c-5p hsa-miR-30c-5p 0.0172462437336177 519 125 14 0.112 0.0269749518304432
MIRNA MIRNA:hsa-miR-4724-5p hsa-miR-4724-5p 0.019344222284606 98 16 3 0.1875 0.0306122448979592
MIRNA MIRNA:hsa-miR-30a-5p hsa-miR-30a-5p 0.0233121299973473 730 34 8 0.235294117647059 0.010958904109589
MIRNA MIRNA:hsa-miR-570-3p hsa-miR-570-3p 0.0250772936544561 178 72 6 0.0833333333333333 0.0337078651685393
MIRNA MIRNA:hsa-miR-3691-3p hsa-miR-3691-3p 0.0267990183291134 105 80 5 0.0625 0.0476190476190476
MIRNA MIRNA:hsa-miR-633 hsa-miR-633 0.0360558083379549 81 115 5 0.0434782608695652 0.0617283950617284
MIRNA MIRNA:hsa-miR-331-3p hsa-miR-331-3p 0.0360558083379549 403 24 5 0.208333333333333 0.0124069478908189
MIRNA MIRNA:hsa-miR-149-5p hsa-miR-149-5p 0.0441140991161614 394 7 3 0.428571428571429 0.00761421319796954
MIRNA MIRNA:hsa-miR-636 hsa-miR-636 0.0441140991161614 100 108 5 0.0462962962962963 0.05
MIRNA MIRNA:hsa-miR-2115-3p hsa-miR-2115-3p 0.0441140991161614 88 31 3 0.0967741935483871 0.0340909090909091
MIRNA MIRNA:hsa-miR-92a-2-5p hsa-miR-92a-2-5p 0.0441140991161614 245 115 8 0.0695652173913043 0.0326530612244898
MIRNA MIRNA:hsa-miR-30e-5p hsa-miR-30e-5p 0.0441140991161614 346 125 10 0.08 0.0289017341040462
MIRNA MIRNA:hsa-miR-183-5p hsa-miR-183-5p 0.0441140991161614 347 18 4 0.222222222222222 0.0115273775216138
MIRNA MIRNA:hsa-miR-29c-3p hsa-miR-29c-3p 0.0441140991161614 253 114 8 0.0701754385964912 0.0316205533596838
MIRNA MIRNA:hsa-miR-25-3p hsa-miR-25-3p 0.0441140991161614 515 6 3 0.5 0.0058252427184466
MIRNA MIRNA:hsa-miR-197-3p hsa-miR-197-3p 0.0467561294591113 407 111 10 0.0900900900900901 0.0245700245700246
REAC REAC:R-HSA-3371568 Attenuation phase 7.3935801153264e-12 14 6 5 0.833333333333333 0.357142857142857
REAC REAC:R-HSA-3371571 HSF1-dependent transactivation 7.84235867876875e-11 24 6 5 0.833333333333333 0.208333333333333
REAC REAC:R-HSA-3371497 HSP90 chaperone cycle for steroid hormone receptors (SHR) 8.76161005566391e-10 57 10 6 0.6 0.105263157894737
REAC REAC:R-HSA-3371556 Cellular response to heat stress 1.11482971813349e-09 87 14 7 0.5 0.0804597701149425
REAC REAC:R-HSA-2262752 Cellular responses to stress 3.00157100449919e-09 546 16 11 0.6875 0.0201465201465201
REAC REAC:R-HSA-8953897 Cellular responses to external stimuli 3.29193273115598e-09 560 16 11 0.6875 0.0196428571428571
REAC REAC:R-HSA-3371453 Regulation of HSF1-mediated heat shock response 1.4428761873461e-08 67 14 6 0.428571428571429 0.0895522388059701
REAC REAC:R-HSA-9613829 Chaperone Mediated Autophagy 1.93195485979306e-07 22 28 5 0.178571428571429 0.227272727272727
REAC REAC:R-HSA-450408 AUF1 (hnRNP D0) binds and destabilizes mRNA 9.05891907343475e-07 54 16 5 0.3125 0.0925925925925926
REAC REAC:R-HSA-5687128 MAPK6/MAPK4 signaling 7.9371293241033e-06 89 29 6 0.206896551724138 0.0674157303370786
REAC REAC:R-HSA-450531 Regulation of mRNA stability by proteins that bind AU-rich elements 7.9371293241033e-06 86 16 5 0.3125 0.0581395348837209
REAC REAC:R-HSA-9615710 Late endosomal microautophagy 8.57307932620807e-05 34 28 4 0.142857142857143 0.117647058823529
REAC REAC:R-HSA-1236382 Constitutive Signaling by Ligand-Responsive EGFR Cancer Variants 8.57307932620807e-05 17 16 3 0.1875 0.176470588235294
REAC REAC:R-HSA-9663891 Selective autophagy 8.57307932620807e-05 80 28 5 0.178571428571429 0.0625
REAC REAC:R-HSA-5637815 Signaling by Ligand-Responsive EGFR Variants in Cancer 8.57307932620807e-05 17 16 3 0.1875 0.176470588235294
REAC REAC:R-HSA-1643713 Signaling by EGFR in Cancer 0.000208164006208084 23 16 3 0.1875 0.130434782608696
REAC REAC:R-HSA-8863795 Downregulation of ERBB2 signaling 0.000304475412520838 27 16 3 0.1875 0.111111111111111
REAC REAC:R-HSA-1632852 Macroautophagy 0.000798682799603615 134 28 5 0.178571428571429 0.0373134328358209
REAC REAC:R-HSA-9646399 Aggrephagy 0.00116322287755164 44 16 3 0.1875 0.0681818181818182
REAC REAC:R-HSA-9612973 Autophagy 0.00121009488784416 149 28 5 0.178571428571429 0.0335570469798658
REAC REAC:R-HSA-1227986 Signaling by ERBB2 0.00121507386373231 46 16 3 0.1875 0.0652173913043478
REAC REAC:R-HSA-6798695 Neutrophil degranulation 0.00150448897611495 474 6 4 0.666666666666667 0.00843881856540084
REAC REAC:R-HSA-168249 Innate Immune System 0.00156385473476387 1073 16 8 0.5 0.00745573159366263
REAC REAC:R-HSA-5683057 MAPK family signaling cascades 0.00156385473476387 308 16 5 0.3125 0.0162337662337662
REAC REAC:R-HSA-9637687 Suppression of phagosomal maturation 0.00197413269040827 13 81 3 0.037037037037037 0.230769230769231
REAC REAC:R-HSA-450294 MAP kinase activation 0.00197413269040827 63 16 3 0.1875 0.0476190476190476
REAC REAC:R-HSA-1169408 ISG15 antiviral mechanism 0.0022794808435632 70 18 3 0.166666666666667 0.0428571428571429
REAC REAC:R-HSA-2559582 Senescence-Associated Secretory Phenotype (SASP) 0.0022794808435632 76 16 3 0.1875 0.0394736842105263
REAC REAC:R-HSA-168142 Toll Like Receptor 10 (TLR10) Cascade 0.0022794808435632 84 16 3 0.1875 0.0357142857142857
REAC REAC:R-HSA-448424 Interleukin-17 signaling 0.0022794808435632 71 16 3 0.1875 0.0422535211267606
REAC REAC:R-HSA-8852276 The role of GTSE1 in G2/M progression after G2 checkpoint 0.0022794808435632 79 16 3 0.1875 0.0379746835443038
REAC REAC:R-HSA-168176 Toll Like Receptor 5 (TLR5) Cascade 0.0022794808435632 84 16 3 0.1875 0.0357142857142857
REAC REAC:R-HSA-8866654 E3 ubiquitin ligases ubiquitinate target proteins 0.0022794808435632 53 109 5 0.0458715596330275 0.0943396226415094
REAC REAC:R-HSA-975871 MyD88 cascade initiated on plasma membrane 0.0022794808435632 84 16 3 0.1875 0.0357142857142857
REAC REAC:R-HSA-2565942 Regulation of PLK1 Activity at G2/M Transition 0.00230771386828748 85 16 3 0.1875 0.0352941176470588
REAC REAC:R-HSA-2559580 Oxidative Stress Induced Senescence 0.00241980512645435 87 16 3 0.1875 0.0344827586206897
REAC REAC:R-HSA-1169410 Antiviral mechanism by IFN-stimulated genes 0.00242003545683735 78 18 3 0.166666666666667 0.0384615384615385
REAC REAC:R-HSA-975138 TRAF6 mediated induction of NFkB and MAP kinases upon TLR7/8 or 9 activation 0.00253226247969214 90 16 3 0.1875 0.0333333333333333
REAC REAC:R-HSA-975155 MyD88 dependent cascade initiated on endosome 0.00255387489712671 91 16 3 0.1875 0.032967032967033
REAC REAC:R-HSA-168181 Toll Like Receptor 7/8 (TLR7/8) Cascade 0.00255387489712671 91 16 3 0.1875 0.032967032967033
REAC REAC:R-HSA-449147 Signaling by Interleukins 0.0025633399238506 446 9 4 0.444444444444444 0.00896860986547085
REAC REAC:R-HSA-168164 Toll Like Receptor 3 (TLR3) Cascade 0.0025633399238506 92 16 3 0.1875 0.0326086956521739
REAC REAC:R-HSA-166058 MyD88:MAL(TIRAP) cascade initiated on plasma membrane 0.0025633399238506 94 16 3 0.1875 0.0319148936170213
REAC REAC:R-HSA-168138 Toll Like Receptor 9 (TLR9) Cascade 0.0025633399238506 95 16 3 0.1875 0.0315789473684211
REAC REAC:R-HSA-168188 Toll Like Receptor TLR6:TLR2 Cascade 0.0025633399238506 94 16 3 0.1875 0.0319148936170213
REAC REAC:R-HSA-166166 MyD88-independent TLR4 cascade 0.00258907091415811 96 16 3 0.1875 0.03125
REAC REAC:R-HSA-937061 TRIF(TICAM1)-mediated TLR4 signaling 0.00258907091415811 96 16 3 0.1875 0.03125
REAC REAC:R-HSA-181438 Toll Like Receptor 2 (TLR2) Cascade 0.00261530262704675 97 16 3 0.1875 0.0309278350515464
REAC REAC:R-HSA-168179 Toll Like Receptor TLR1:TLR2 Cascade 0.00261530262704675 97 16 3 0.1875 0.0309278350515464
REAC REAC:R-HSA-6804757 Regulation of TP53 Degradation 0.00286404349793183 36 44 3 0.0681818181818182 0.0833333333333333
REAC REAC:R-HSA-6806003 Regulation of TP53 Expression and Degradation 0.00300327237106043 37 44 3 0.0681818181818182 0.0810810810810811
REAC REAC:R-HSA-5357956 TNFR1-induced NFkappaB signaling pathway 0.00314224836510018 30 56 3 0.0535714285714286 0.1
REAC REAC:R-HSA-8953854 Metabolism of RNA 0.00325695734137546 658 18 6 0.333333333333333 0.00911854103343465
REAC REAC:R-HSA-1169091 Activation of NF-kappaB in B cells 0.00332380348114052 67 61 4 0.0655737704918033 0.0597014925373134
REAC REAC:R-HSA-5357905 Regulation of TNFR1 signaling 0.00347550174259916 32 56 3 0.0535714285714286 0.09375
REAC REAC:R-HSA-166016 Toll Like Receptor 4 (TLR4) Cascade 0.00412180031201695 126 16 3 0.1875 0.0238095238095238
REAC REAC:R-HSA-8852135 Protein ubiquitination 0.00441705888138637 73 109 5 0.0458715596330275 0.0684931506849315
REAC REAC:R-HSA-8939211 ESR-mediated signaling 0.00457158838544772 181 12 3 0.25 0.0165745856353591
REAC REAC:R-HSA-422475 Axon guidance 0.00470745208117331 549 16 5 0.3125 0.00910746812386157
REAC REAC:R-HSA-6807070 PTEN Regulation 0.0048622783729057 138 16 3 0.1875 0.0217391304347826
REAC REAC:R-HSA-1168372 Downstream signaling events of B Cell Receptor (BCR) 0.00504412979858656 80 61 4 0.0655737704918033 0.05
REAC REAC:R-HSA-8856828 Clathrin-mediated endocytosis 0.00524243564101269 144 16 3 0.1875 0.0208333333333333
REAC REAC:R-HSA-9675108 Nervous system development 0.00524243564101269 574 16 5 0.3125 0.00871080139372822
REAC REAC:R-HSA-75893 TNF signaling 0.00575750296132234 42 56 3 0.0535714285714286 0.0714285714285714
REAC REAC:R-HSA-168898 Toll-like Receptor Cascades 0.00575750296132234 152 16 3 0.1875 0.0197368421052632
REAC REAC:R-HSA-9609507 Protein localization 0.0059794725097409 158 16 3 0.1875 0.0189873417721519
REAC REAC:R-HSA-2559583 Cellular Senescence 0.00602153428771247 159 16 3 0.1875 0.0188679245283019
REAC REAC:R-HSA-5668541 TNFR2 non-canonical NF-kB pathway 0.00688851436333389 100 56 4 0.0714285714285714 0.04
REAC REAC:R-HSA-5653656 Vesicle-mediated transport 0.00720394065114561 717 9 4 0.444444444444444 0.00557880055788006
REAC REAC:R-HSA-1280215 Cytokine Signaling in Immune system 0.00724528806689329 842 18 6 0.333333333333333 0.00712589073634204
REAC REAC:R-HSA-2454202 Fc epsilon receptor (FCERI) signaling 0.00801975895890371 182 16 3 0.1875 0.0164835164835165
REAC REAC:R-HSA-9006931 Signaling by Nuclear Receptors 0.00859061743453487 255 12 3 0.25 0.0117647058823529
REAC REAC:R-HSA-69275 G2/M Transition 0.00904019424271081 196 16 3 0.1875 0.0153061224489796
REAC REAC:R-HSA-157118 Signaling by NOTCH 0.00904378875208179 197 16 3 0.1875 0.0152284263959391
REAC REAC:R-HSA-453274 Mitotic G2-G2/M phases 0.00904378875208179 198 16 3 0.1875 0.0151515151515152
REAC REAC:R-HSA-5663205 Infectious disease 0.00925228927863832 815 9 4 0.444444444444444 0.0049079754601227
REAC REAC:R-HSA-168256 Immune System 0.00925609330578598 2139 9 6 0.666666666666667 0.00280504908835905
REAC REAC:R-HSA-9033241 Peroxisomal protein import 0.00944553900894144 60 109 4 0.036697247706422 0.0666666666666667
REAC REAC:R-HSA-977225 Amyloid fiber formation 0.0095257504519483 73 90 4 0.0444444444444444 0.0547945205479452
REAC REAC:R-HSA-1266738 Developmental Biology 0.00953919872039887 1069 16 6 0.375 0.00561272217025257
REAC REAC:R-HSA-913531 Interferon Signaling 0.010237431146373 191 18 3 0.166666666666667 0.0157068062827225
REAC REAC:R-HSA-5633007 Regulation of TP53 Activity 0.0109038990122506 160 44 4 0.0909090909090909 0.025
REAC REAC:R-HSA-9006934 Signaling by Receptor Tyrosine Kinases 0.0122025684779337 485 16 4 0.25 0.00824742268041237
REAC REAC:R-HSA-1257604 PIP3 activates AKT signaling 0.0130546598693545 249 16 3 0.1875 0.0120481927710843
REAC REAC:R-HSA-6804756 Regulation of TP53 Activity through Phosphorylation 0.0135507924400418 92 43 3 0.0697674418604651 0.0326086956521739
REAC REAC:R-HSA-3700989 Transcriptional Regulation by TP53 0.0145519902971451 360 50 6 0.12 0.0166666666666667
REAC REAC:R-HSA-9031628 NGF-stimulated transcription 0.0162295926091819 39 111 3 0.027027027027027 0.0769230769230769
REAC REAC:R-HSA-9006925 Intracellular signaling by second messengers 0.0175176784746795 289 16 3 0.1875 0.0103806228373702
REAC REAC:R-HSA-2672351 Stimuli-sensing channels 0.018632985410761 105 44 3 0.0681818181818182 0.0285714285714286
REAC REAC:R-HSA-983705 Signaling by the B Cell Receptor (BCR) 0.027493509436883 164 61 4 0.0655737704918033 0.024390243902439
REAC REAC:R-HSA-5668914 Diseases of metabolism 0.0275772764109508 241 23 3 0.130434782608696 0.012448132780083
REAC REAC:R-HSA-162599 Late Phase of HIV Life Cycle 0.0311422215808038 134 43 3 0.0697674418604651 0.0223880597014925
REAC REAC:R-HSA-68886 M Phase 0.031157395017629 371 16 3 0.1875 0.00808625336927224
REAC REAC:R-HSA-5663202 Diseases of signal transduction by growth factor receptors and second messengers 0.031157395017629 371 16 3 0.1875 0.00808625336927224
REAC REAC:R-HSA-983712 Ion channel transport 0.0452395188338393 182 97 5 0.0515463917525773 0.0274725274725275
REAC REAC:R-HSA-198725 Nuclear Events (kinase and transcription factor activation) 0.0453790848844552 61 111 3 0.027027027027027 0.0491803278688525
REAC REAC:R-HSA-446203 Asparagine N-linked glycosylation 0.0467503242384747 304 23 3 0.130434782608696 0.00986842105263158
REAC REAC:R-HSA-1643685 Disease 0.0486849938762285 1509 9 4 0.444444444444444 0.00265076209410205
TF TF:M09950_1 Factor: HSF1; motif: NRGAANNTTCYRGAA; match class: 1 1.70980218411034e-16 266 32 15 0.46875 0.056390977443609
TF TF:M11656_1 Factor: HSF1; motif: RGAANRTTCYRGAAN; match class: 1 2.6951302228349e-16 219 14 11 0.785714285714286 0.0502283105022831
TF TF:M11655_1 Factor: HSF1; motif: NGAANGTTCKRGAAN; match class: 1 3.42028328630072e-15 93 32 11 0.34375 0.118279569892473
TF TF:M11654_1 Factor: HSF1; motif: RGAANRTTCYRGAAN; match class: 1 5.22811779271513e-15 113 13 9 0.692307692307692 0.079646017699115
TF TF:M07100_1 Factor: HSF1; motif: NTTCTRGAANNTTCY; match class: 1 1.82617181331996e-14 514 32 16 0.5 0.0311284046692607
TF TF:M11655 Factor: HSF1; motif: NGAANGTTCKRGAAN 2.96247013440197e-14 1207 19 16 0.842105263157895 0.0132560066280033
TF TF:M01023_1 Factor: HSF1; motif: NTTCTRGAAVNTTCTYM; match class: 1 8.91187729249547e-14 254 14 10 0.714285714285714 0.0393700787401575
TF TF:M11654 Factor: HSF1; motif: RGAANRTTCYRGAAN 3.68088151136586e-13 1353 32 20 0.625 0.0147819660014782
TF TF:M11656 Factor: HSF1; motif: RGAANRTTCYRGAAN 1.65610487673143e-12 2033 47 27 0.574468085106383 0.0132808657156911
TF TF:M09950 Factor: HSF1; motif: NRGAANNTTCYRGAA 2.52128496003227e-11 2501 47 28 0.595744680851064 0.0111955217912835
TF TF:M07100 Factor: HSF1; motif: NTTCTRGAANNTTCY 5.93593247766654e-11 3350 47 31 0.659574468085106 0.00925373134328358
TF TF:M01023 Factor: HSF1; motif: NTTCTRGAAVNTTCTYM 6.99567718834319e-10 2721 52 29 0.557692307692308 0.0106578463800074
TF TF:M11657 Factor: HSF1; motif: NGAANRTTCKAGAAN 7.41887800350074e-10 337 102 17 0.166666666666667 0.0504451038575668
TF TF:M11662 Factor: HSF2; motif: RGAANGTTCYRGAAN 4.61629690329898e-09 272 32 10 0.3125 0.0367647058823529
TF TF:M11658 Factor: HSF4; motif: RGAANNTTCYRGAAN 5.0013796196439e-09 400 98 17 0.173469387755102 0.0425
TF TF:M11659 Factor: HSF4; motif: NGAANRTTCTAGAAN 5.02929505360733e-09 329 102 16 0.156862745098039 0.0486322188449848
TF TF:M04008 Factor: HSF1; motif: TTCTAGAAYNTTC 1.67113713064338e-08 358 102 16 0.156862745098039 0.0446927374301676
TF TF:M11662_1 Factor: HSF2; motif: RGAANGTTCYRGAAN; match class: 1 1.92886118490953e-08 12 13 4 0.307692307692308 0.333333333333333
TF TF:M00147_1 Factor: HSF2; motif: NGAANNWTCK; match class: 1 7.16401199242554e-08 4404 20 18 0.9 0.00408719346049046
TF TF:M11658_1 Factor: HSF4; motif: RGAANNTTCYRGAAN; match class: 1 1.35584937576136e-07 19 13 4 0.307692307692308 0.210526315789474
TF TF:M01244 Factor: HSF2; motif: GAANRTTCTAGAA 2.96819273562376e-07 582 102 18 0.176470588235294 0.0309278350515464
TF TF:M02017 Factor: HSF1; motif: GAANNTTCTRGNAN 9.26461757856755e-07 4046 27 20 0.740740740740741 0.00494315373208107
TF TF:M11657_1 Factor: HSF1; motif: NGAANRTTCKAGAAN; match class: 1 1.81521392235324e-06 15 31 4 0.129032258064516 0.266666666666667
TF TF:M00147 Factor: HSF2; motif: NGAANNWTCK 7.43574930819854e-06 5830 20 18 0.9 0.00308747855917667
TF TF:M04008_1 Factor: HSF1; motif: TTCTAGAAYNTTC; match class: 1 1.91313774363899e-05 14 13 3 0.230769230769231 0.214285714285714
TF TF:M11659_1 Factor: HSF4; motif: NGAANRTTCTAGAAN; match class: 1 1.91313774363899e-05 14 13 3 0.230769230769231 0.214285714285714
TF TF:M04010 Factor: HSF4; motif: TTCTAGAANNTTC 1.91313774363899e-05 185 13 5 0.384615384615385 0.027027027027027
TF TF:M07459_1 Factor: HSF1; motif: GAANNTTCTNGN; match class: 1 2.99131673641546e-05 413 30 8 0.266666666666667 0.0193704600484262
TF TF:M00641 Factor: HSF; motif: TTCCMGARGYTTC 4.75901429111124e-05 3599 9 9 1 0.00250069463739928
TF TF:M01244_1 Factor: HSF2; motif: GAANRTTCTAGAA; match class: 1 0.000105461391826817 25 13 3 0.230769230769231 0.12
TF TF:M07259_1 Factor: HSF1; motif: TCYAGAANNTTC; match class: 1 0.000180641113957404 732 30 9 0.3 0.0122950819672131
TF TF:M07250_1 Factor: E2F-1; motif: NNNSSCGCSAANN; match class: 1 0.000295414350655978 5515 36 24 0.666666666666667 0.0043517679057117
TF TF:M11601_1 Factor: TCF-1; motif: ACATCGRGRCGCTGW; match class: 1 0.000327107936681672 11053 33 31 0.939393939393939 0.00280466841581471
TF TF:M07259 Factor: HSF1; motif: TCYAGAANNTTC 0.000361073123514737 4742 14 12 0.857142857142857 0.00253057781526782
TF TF:M04869_1 Factor: Egr-1; motif: GCGCATGCG; match class: 1 0.000361073123514737 10253 33 30 0.909090909090909 0.00292597288598459
TF TF:M04869 Factor: Egr-1; motif: GCGCATGCG 0.000474950742804476 11232 33 31 0.939393939393939 0.00275997150997151
TF TF:M07459 Factor: HSF1; motif: GAANNTTCTNGN 0.000485425430264663 3422 20 13 0.65 0.0037989479836353
TF TF:M04001 Factor: GCM1; motif: NATGCGGGTAC 0.000529613670810359 388 13 5 0.384615384615385 0.0128865979381443
TF TF:M07358 Factor: HSF2; motif: NGGAATNTTCTNGNRN 0.000740918435905377 576 10 5 0.5 0.00868055555555556
TF TF:M11880_1 Factor: pax-6; motif: NYACGCWTSANYGMNCN; match class: 1 0.00082593326306679 7046 41 29 0.707317073170732 0.00411581038887312
TF TF:M11882_1 Factor: pax-6; motif: NYACGCNYSANYGMNCN; match class: 1 0.000838539681397426 11423 37 34 0.918918918918919 0.00297645101987219
TF TF:M08884 Factor: GCM; motif: NNNNATGMGGGN 0.00157146997808228 1185 15 7 0.466666666666667 0.00590717299578059
TF TF:M03574 Factor: GCMa; motif: CCCGCAT 0.00167350880106272 2362 15 9 0.6 0.00381033022861981
TF TF:M02017_1 Factor: HSF1; motif: GAANNTTCTRGNAN; match class: 1 0.00214999600693593 543 13 5 0.384615384615385 0.00920810313075507
TF TF:M04002 Factor: GCMb; motif: NATGCGGGTN 0.00247132025792644 1282 15 7 0.466666666666667 0.00546021840873635
TF TF:M11883 Factor: pax-6; motif: NYACGCNTSRNYGCNYN 0.00318957589164862 13445 35 34 0.971428571428571 0.00252882112309409
TF TF:M11271 Factor: JunD; motif: NRTGACGCAYN 0.00324680299177108 7009 21 17 0.80952380952381 0.00242545298901412
TF TF:M11603_1 Factor: TCF-1; motif: ACATCGRGRCGCTGW; match class: 1 0.00346302677102451 13184 33 32 0.96969696969697 0.00242718446601942
TF TF:M09732_1 Factor: RFX3; motif: NYNCCMTGGCAACM; match class: 1 0.00366473763854067 982 14 6 0.428571428571429 0.00610997963340122
TF TF:M08917 Factor: GABP-ALPHA; motif: RCCGGAARTNN 0.00394140044799596 2702 18 10 0.555555555555556 0.00370096225018505
TF TF:M00737_1 Factor: E2F-1:DP-2; motif: TTTSSCGC; match class: 1 0.00408614997825201 2933 96 30 0.3125 0.0102284350494374
TF TF:M04106 Factor: RUNX2; motif: NRACCGCAAACCGCAN 0.00466429621935051 13833 43 41 0.953488372093023 0.00296392684161064
TF TF:M04950_1 Factor: Egr-1; motif: NGCGTGCGY; match class: 1 0.00466429621935051 5551 41 24 0.585365853658537 0.00432354530715186
TF TF:M10635_1 Factor: Nkx2-3; motif: GNCGTTRAG; match class: 1 0.00466429621935051 703 3 3 1 0.0042674253200569
TF TF:M02053 Factor: ELF1; motif: NCCGGAARTN 0.00507392881112518 6033 18 14 0.777777777777778 0.00232057019724847
TF TF:M11486 Factor: CP2; motif: AACCGGTTNNAACCGGTT 0.00538314726643385 3658 55 23 0.418181818181818 0.00628758884636413
TF TF:M00986 Factor: Churchill; motif: CGGGNN 0.0055998512226536 14197 38 37 0.973684210526316 0.00260618440515602
TF TF:M09894_1 Factor: E2F-4; motif: SNGGGCGGGAANN; match class: 1 0.0055998512226536 13929 36 35 0.972222222222222 0.0025127431976452
TF TF:M11881_1 Factor: pax-6; motif: NYACGCNTSANYGCNYN; match class: 1 0.0055998512226536 7158 18 15 0.833333333333333 0.00209555741827326
TF TF:M00634 Factor: GCM; motif: CNNRCCCGCATD 0.00591161097107584 2152 15 8 0.533333333333333 0.00371747211895911
TF TF:M03824 Factor: GCMb; motif: RCCCKCAT 0.00618956978607328 1550 15 7 0.466666666666667 0.00451612903225806
TF TF:M11596 Factor: GCMb; motif: ATGCGGGYN 0.00656923484919136 737 13 5 0.384615384615385 0.0067842605156038
TF TF:M08205_1 Factor: E2F-1:Elk-1; motif: SGCGCSNNAMCGGAAGT; match class: 1 0.00673783795035145 10438 34 29 0.852941176470588 0.00277831002107683
TF TF:M02056 Factor: ELF4; motif: NCCGGAARTN 0.00686869547170679 5332 18 13 0.722222222222222 0.00243810952738185
TF TF:M11485_1 Factor: CP2; motif: AACCGGTTNNAACCGGTT; match class: 1 0.00686869547170679 6203 52 30 0.576923076923077 0.00483636949862969
TF TF:M05444 Factor: CPBP; motif: NGGGCGG 0.00686869547170679 8578 18 16 0.888888888888889 0.00186523665190021
TF TF:M00144_1 Factor: Pax-5; motif: RRMSWGANWYCTNRAGCGKRACSRYNSM; match class: 1 0.00686869547170679 7128 113 61 0.539823008849557 0.00855780022446689
TF TF:M05332 Factor: Sp2; motif: WGGGCGG 0.00686869547170679 8578 18 16 0.888888888888889 0.00186523665190021
TF TF:M05361 Factor: Sp6; motif: WGGGCGG 0.00686869547170679 8578 18 16 0.888888888888889 0.00186523665190021
TF TF:M04826_1 Factor: p300; motif: ACNTCCG; match class: 1 0.00749839798968467 15260 36 36 1 0.00235910878112713
TF TF:M08344 Factor: HOXB2:ER81; motif: ACCGGAAATGA 0.00769972866192 101 18 3 0.166666666666667 0.0297029702970297
TF TF:M08213 Factor: Elk-1:TBR2; motif: TNRCACCGGAAGN 0.00771384043306312 6273 52 30 0.576923076923077 0.00478240076518412
TF TF:M11485 Factor: CP2; motif: AACCGGTTNNAACCGGTT 0.00774499489019048 6977 52 32 0.615384615384615 0.00458649849505518
TF TF:M00146 Factor: HSF1; motif: AGAANRTTCN 0.00774499489019048 2678 20 10 0.5 0.00373412994772218
TF TF:M02074 Factor: GABPalpha; motif: RCCGGAWRYN 0.00774499489019048 4607 44 22 0.5 0.00477534187106577
TF TF:M11881 Factor: pax-6; motif: NYACGCNTSANYGCNYN 0.00858827682031868 13174 35 33 0.942857142857143 0.00250493396083194
TF TF:M08423 Factor: TEF-3:ER81; motif: ACCGGAAATRCC 0.00873167978347498 3845 18 11 0.611111111111111 0.00286085825747724
TF TF:M08913 Factor: FLI-1; motif: NAYTTCCGGT 0.00968496529353901 8322 44 31 0.704545454545455 0.00372506608988224
TF TF:M02102 Factor: NRF-1; motif: YGCGCMTGCGC 0.00971228061750577 2020 26 10 0.384615384615385 0.00495049504950495
TF TF:M10635 Factor: Nkx2-3; motif: GNCGTTRAG 0.00979571819325818 4594 16 11 0.6875 0.00239442751414889
TF TF:M03821 Factor: ER-beta; motif: ANNSTGACCYRGNN 0.0100168664506074 6456 24 17 0.708333333333333 0.00263320941759603
TF TF:M11018_1 Factor: IRX-1; motif: NACRYNNNNNNNNRYGNN; match class: 1 0.0101453308579204 15920 41 41 1 0.00257537688442211
TF TF:M00113_1 Factor: CREB; motif: NNGNTGACGTNN; match class: 1 0.0105120620658277 869 115 15 0.130434782608696 0.0172612197928654
TF TF:M02067 Factor: ER71; motif: ACCGGAARYN 0.0109488954335627 5930 58 31 0.53448275862069 0.00522765598650927
TF TF:M02066 Factor: PEA3; motif: RCCGGAAGYN 0.0110106790365324 7045 61 36 0.590163934426229 0.00511000709723208
TF TF:M03988 Factor: FLI1; motif: ACCGGAARTN 0.0110106790365324 8318 59 39 0.661016949152542 0.00468862707381582
TF TF:M09632 Factor: Kaiso; motif: GNTCTCGCGAGRNNNNGGN 0.0110106790365324 3001 53 19 0.358490566037736 0.00633122292569144
TF TF:M09608_1 Factor: Erg; motif: NNACCGGAARTSN; match class: 1 0.0110106790365324 2389 50 16 0.32 0.00669736291335287
TF TF:M09905 Factor: SAP-1; motif: NNCCGGAAGTGN 0.0115088381877217 8273 65 42 0.646153846153846 0.00507675571135018
TF TF:M09887 Factor: CREB1; motif: NRRTGACGTMA 0.0115088381877217 5419 30 18 0.6 0.0033216460601587
TF TF:M11218_1 Factor: CREB1; motif: NRTGAYGCGTN; match class: 1 0.011690876368431 2438 27 11 0.407407407407407 0.00451189499589828
TF TF:M10849_1 Factor: Cdx-2; motif: NRTCGTAANNNN; match class: 1 0.011690876368431 4497 120 45 0.375 0.0100066711140761
TF TF:M11529_1 Factor: E2F-2; motif: GCGCGCGCNCS; match class: 1 0.0117136269480506 14473 36 35 0.972222222222222 0.0024182961376356
TF TF:M11880 Factor: pax-6; motif: NYACGCWTSANYGMNCN 0.0117136269480506 13087 33 31 0.939393939393939 0.00236876289447543
TF TF:M06292 Factor: ZNF766; motif: NCGTGAAGGAAA 0.0117911612650439 146 114 6 0.0526315789473684 0.0410958904109589
TF TF:M09832 Factor: RFX1; motif: NGTTGCCATGG 0.0118355070676544 2370 4 4 1 0.00168776371308017
TF TF:M11962_1 Factor: rfx1; motif: NGTTRCCATGGYAACN; match class: 1 0.0119114789094172 3181 10 7 0.7 0.00220056585979252
TF TF:M03975_1 Factor: ERG; motif: ACCGGAARTN; match class: 1 0.0119114789094172 4024 48 21 0.4375 0.00521868787276342
TF TF:M03975 Factor: ERG; motif: ACCGGAARTN 0.0119114789094172 10002 94 65 0.691489361702128 0.00649870025994801
TF TF:M02106 Factor: NF-YA; motif: CRGCCAATCAGNRN 0.0122307690898864 1741 68 16 0.235294117647059 0.00919012062033314
TF TF:M11660 Factor: HSF2; motif: RGAAYRTTCYRGAAN 0.0122673438038895 66 89 4 0.0449438202247191 0.0606060606060606
TF TF:M05837 Factor: ZFP2; motif: NCCWCGGGRATA 0.0125819231704532 188 32 4 0.125 0.0212765957446809
TF TF:M11962 Factor: rfx1; motif: NGTTRCCATGGYAACN 0.0128330748040008 3235 10 7 0.7 0.00216383307573416
TF TF:M08377_1 Factor: meis1:Elf-1; motif: NTGCCGGAAGTN; match class: 1 0.013134776595292 5051 40 21 0.525 0.00415759255592952
TF TF:M01865 Factor: BTEB3; motif: BNRNGGGAGGNGT 0.0143498806715355 9899 35 28 0.8 0.002828568542277
TF TF:M09668_1 Factor: RelA-p65; motif: GGGRNTTTCCM; match class: 1 0.0143840731263979 513 119 11 0.092436974789916 0.0214424951267057
TF TF:M00803 Factor: E2F; motif: GGCGSG 0.0143840731263979 13190 38 35 0.921052631578947 0.00265352539802881
TF TF:M00209 Factor: NF-Y; motif: NCTGATTGGYTASY 0.014441354584336 3776 123 40 0.32520325203252 0.0105932203389831
TF TF:M10438_1 Factor: ZF5; motif: GGSGCGCGS; match class: 1 0.014441354584336 14873 115 102 0.88695652173913 0.00685806494990923
TF TF:M11486_1 Factor: CP2; motif: AACCGGTTNNAACCGGTT; match class: 1 0.0148379832531549 2952 87 26 0.298850574712644 0.00880758807588076
TF TF:M11883_1 Factor: pax-6; motif: NYACGCNTSRNYGCNYN; match class: 1 0.0154156659148107 7768 29 21 0.724137931034483 0.00270339855818744
TF TF:M01861_1 Factor: ATF-1; motif: TNACGTCAN; match class: 1 0.0154156659148107 1896 20 8 0.4 0.00421940928270042
TF TF:M04823_1 Factor: E2F-4; motif: NNTTCCCGCCNN; match class: 1 0.0154156659148107 7850 27 20 0.740740740740741 0.00254777070063694
TF TF:M00428 Factor: E2F-1; motif: NKTSSCGC 0.0166548572389829 8947 123 75 0.609756097560976 0.00838269811109869
TF TF:M08525_1 Factor: E2F-1:HES-7; motif: GGCRCGTGSYNNWNGGCGCSM; match class: 1 0.0169405350829058 15268 41 40 0.975609756097561 0.00261985852763951
TF TF:M05439_1 Factor: RREB-1; motif: GGGWCSA; match class: 1 0.017029459231707 3200 37 15 0.405405405405405 0.0046875
TF TF:M08800 Factor: ARNT; motif: YRCGTGNN 0.0179971133347585 914 22 6 0.272727272727273 0.00656455142231947
TF TF:M05916 Factor: ZNF407; motif: NGGTGAAARARC 0.0180858822563396 124 23 3 0.130434782608696 0.0241935483870968
TF TF:M10628 Factor: NKX3A; motif: NTCGTTAN 0.0180858822563396 4543 102 39 0.382352941176471 0.00858463570327977
TF TF:M00981 Factor: CREB,; motif: NTGACGTNA 0.0180858822563396 8345 119 69 0.579831932773109 0.00826842420611144
TF TF:M04691_1 Factor: Kaiso; motif: TCTCGCGAG; match class: 1 0.0180858822563396 10488 40 32 0.8 0.0030511060259344
TF TF:M11733 Factor: PXR; motif: NYGAACTSNNTGAACTC 0.0186002076452089 2983 6 5 0.833333333333333 0.00167616493462957
TF TF:M01593 Factor: Zfx; motif: SNSCAGGCCKCGSCSS 0.0186565267581155 4163 5 5 1 0.00120105693009849
TF TF:M11392 Factor: Erg; motif: NACCGGAARYN 0.0186973471661887 8690 94 58 0.617021276595745 0.00667433831990794
TF TF:M00113 Factor: CREB; motif: NNGNTGACGTNN 0.0186973471661887 4801 32 17 0.53125 0.0035409289731306
TF TF:M12000_1 Factor: AML3; motif: NNAACCGCAAWAACCGCAAN; match class: 1 0.0195453110601843 1586 14 6 0.428571428571429 0.00378310214375788
TF TF:M01770 Factor: XBP-1; motif: WNNGMCACGTC 0.0195509465124469 11003 123 87 0.707317073170732 0.00790693447241661
TF TF:M00736_1 Factor: E2F-1:DP-1; motif: TTTCSCGC; match class: 1 0.0205172439475399 4639 88 35 0.397727272727273 0.00754472946755766
TF TF:M01299 Factor: MECP2; motif: CCGGNNTTWA 0.0205172439475399 5228 82 36 0.439024390243902 0.00688599846977812
TF TF:M09600 Factor: CREB1; motif: TKACGTCAYNN 0.0205212404341363 5324 45 23 0.511111111111111 0.00432006010518407
TF TF:M00803_1 Factor: E2F; motif: GGCGSG; match class: 1 0.0206840933685446 10230 41 32 0.780487804878049 0.00312805474095797
TF TF:M00178_1 Factor: CREB; motif: NSTGACGTMANN; match class: 1 0.0206840933685446 1522 107 19 0.177570093457944 0.0124835742444152
TF TF:M00976_1 Factor: AhR,; motif: NRCGTGNGN; match class: 1 0.0213299873448853 1011 29 7 0.241379310344828 0.00692383778437191
TF TF:M08905_1 Factor: TIEG1; motif: GGSGGKGNNN; match class: 1 0.0213299873448853 1017 4 3 0.75 0.00294985250737463
TF TF:M00017 Factor: ATF; motif: CNSTGACGTNNNYC 0.0213953627820141 7226 120 62 0.516666666666667 0.00858012731801827
TF TF:M00179 Factor: ATF2; motif: VGTGACGTMACN 0.0215209021643643 6065 119 54 0.453781512605042 0.0089035449299258
TF TF:M00716_1 Factor: ZF5; motif: GSGCGCGR; match class: 1 0.0215760415702685 14106 30 29 0.966666666666667 0.00205586275343825
TF TF:M02069 Factor: Erm; motif: ACCGGAAGTN 0.0215760415702685 6892 43 26 0.604651162790698 0.00377248984329658
TF TF:M09641 Factor: NRF-1; motif: SYGCGCMTGCGCRNNGSN 0.0215760415702685 3222 27 12 0.444444444444444 0.0037243947858473
TF TF:M09732 Factor: RFX3; motif: NYNCCMTGGCAACM 0.0215760415702685 5207 14 10 0.714285714285714 0.00192049164586134
TF TF:M02062 Factor: Erg; motif: ACCGGAAGTN 0.0218813009854909 8056 59 37 0.627118644067797 0.00459285004965243
TF TF:M07206_1 Factor: E2F-1; motif: NGGGCGGGARV; match class: 1 0.0224542819677188 10849 41 33 0.804878048780488 0.00304175500046087
TF TF:M11404 Factor: Fli-1; motif: NACCGGAARTN 0.0224542819677188 8743 59 39 0.661016949152542 0.00446071142628388
TF TF:M00737 Factor: E2F-1:DP-2; motif: TTTSSCGC 0.0224542819677188 8771 41 29 0.707317073170732 0.00330635047315015
TF TF:M08225_1 Factor: Elk-1:Pax-5; motif: ACCGGAACYACGCWTSANYG; match class: 1 0.0224542819677188 7993 44 29 0.659090909090909 0.00362817465282122
TF TF:M11882 Factor: pax-6; motif: NYACGCNYSANYGMNCN 0.0224542819677188 15490 41 40 0.975609756097561 0.0025823111684958
TF TF:M08266_1 Factor: ER71:Pax-5; motif: ACCGGAACYACGCWTSANTG; match class: 1 0.0224542819677188 8979 13 12 0.923076923076923 0.00133645172068159
TF TF:M11961_1 Factor: rfx1; motif: NGTTRCCATGGYAACN; match class: 1 0.0224542819677188 4172 14 9 0.642857142857143 0.00215723873441994
TF TF:M10945 Factor: VSX1; motif: NTCRTTAN 0.0226175514287832 3019 62 20 0.32258064516129 0.00662471016893011
TF TF:M10936 Factor: CHX10; motif: NTCRTTAN 0.0226175514287832 3019 62 20 0.32258064516129 0.00662471016893011
TF TF:M08526_1 Factor: E2F-3:HES-7; motif: NNNSGCGCSNNNNNCRCGYGNN; match class: 1 0.0226175514287832 14997 36 35 0.972222222222222 0.002333800093352
TF TF:M10874 Factor: alx3; motif: NKCRTTAN 0.0226175514287832 3019 62 20 0.32258064516129 0.00662471016893011
TF TF:M10942 Factor: VSX1; motif: NTCRTTAN 0.0226175514287832 3019 62 20 0.32258064516129 0.00662471016893011
TF TF:M10939 Factor: CHX10; motif: NTCRTTAN 0.0226175514287832 3019 62 20 0.32258064516129 0.00662471016893011
TF TF:M10747 Factor: GSH2; motif: NTCRTTAN 0.0226175514287832 3019 62 20 0.32258064516129 0.00662471016893011
TF TF:M10563 Factor: Msx-1; motif: NTCRTTAN 0.0226175514287832 3019 62 20 0.32258064516129 0.00662471016893011
TF TF:M00279 Factor: MIF-1; motif: NNGTTGCWWGGYAACNGS 0.0226175514287832 11259 59 46 0.779661016949153 0.00408562039257483
TF TF:M09592_1 Factor: ATF-1; motif: NRTGACGTMAN; match class: 1 0.0226175514287832 1255 101 16 0.158415841584158 0.0127490039840637
TF TF:M00025 Factor: Elk-1; motif: NNNNCCGGAARTNN 0.0231155574617022 10262 65 47 0.723076923076923 0.00458000389787566
TF TF:M09826 Factor: BTEB3; motif: CCNNSCCNSCCCCKCCCCC 0.0231155574617022 11467 34 29 0.852941176470588 0.00252899625010901
TF TF:M11961 Factor: rfx1; motif: NGTTRCCATGGYAACN 0.0231574409328381 4244 14 9 0.642857142857143 0.00212064090480679
TF TF:M11597 Factor: GCMb; motif: ATGCGGGTN 0.0232934300486964 1192 13 5 0.384615384615385 0.00419463087248322
TF TF:M01858 Factor: AP-2beta; motif: GCNNNGGSCNGVGGGN 0.0233500013279365 7418 35 23 0.657142857142857 0.0031005661903478
TF TF:M00333_1 Factor: ZF5; motif: NRNGNGCGCGCWN; match class: 1 0.0235017518543128 12401 35 31 0.885714285714286 0.00249979840335457
TF TF:M02052_1 Factor: EHF; motif: CSCGGAARTN; match class: 1 0.0237111678977513 4056 20 11 0.55 0.0027120315581854
TF TF:M00986_1 Factor: Churchill; motif: CGGGNN; match class: 1 0.0237111678977513 10357 35 28 0.8 0.00270348556531814
TF TF:M12085 Factor: ZNF501; motif: NNNCSACGCGAACAC 0.0237111678977513 8467 37 26 0.702702702702703 0.00307074524625015
TF TF:M11400 Factor: Fli-1; motif: NACCGGAARTN 0.0239281509432209 9946 52 38 0.730769230769231 0.0038206314096119
TF TF:M11490 Factor: LBP-1; motif: NRCCGGTNNNNACCGGYN 0.024447286349159 6748 107 53 0.495327102803738 0.00785417901600474
TF TF:M01861 Factor: ATF-1; motif: TNACGTCAN 0.024447286349159 6294 119 55 0.46218487394958 0.00873848109310454
TF TF:M09892_1 Factor: E2F-1; motif: NNNNGGCGGGAARN; match class: 1 0.024819851050631 9162 35 26 0.742857142857143 0.00283780833879066
TF TF:M00695 Factor: ETF; motif: GVGGMGG 0.0251593889239843 10430 41 32 0.780487804878049 0.00306807286673058
TF TF:M04823 Factor: E2F-4; motif: NNTTCCCGCCNN 0.0256416149651293 12747 41 36 0.878048780487805 0.00282419392798305
TF TF:M07313 Factor: ATF-3; motif: SNTGACGYNATN 0.0258947289865662 2894 119 31 0.260504201680672 0.0107118175535591
TF TF:M01104 Factor: MOVO-B; motif: GNGGGGG 0.0258995753523001 10261 15 14 0.933333333333333 0.00136438943572751
TF TF:M07302 Factor: NF-Y; motif: RGCCAATCRGN 0.0261156185711664 1576 68 14 0.205882352941176 0.00888324873096447
TF TF:M12351 Factor: TIEG1; motif: NCCCNSNCCCCGCCCCC 0.0261156185711664 12302 57 47 0.824561403508772 0.00382051698910746
TF TF:M10638_1 Factor: Nkx2-3; motif: NNCGTTRWS; match class: 1 0.0261156185711664 4099 90 32 0.355555555555556 0.00780678214198585
TF TF:M11531 Factor: E2F-2; motif: GCGCGCGCGYW 0.0265790850723376 13270 35 32 0.914285714285714 0.00241145440844009
TF TF:M04027 Factor: MEIS1; motif: NTGACAN 0.0267926163103508 3387 4 4 1 0.00118098612341305
TF TF:M03558_1 Factor: P73; motif: GNNNRRRCNTGCMNNTSASN; match class: 1 0.026949151859227 822 28 6 0.214285714285714 0.0072992700729927
TF TF:M10638 Factor: Nkx2-3; motif: NNCGTTRWS 0.026949151859227 10804 66 49 0.742424242424242 0.0045353572750833
TF TF:M12160 Factor: KLF15; motif: RCCMCRCCCMCN 0.0273324427543662 12729 16 16 1 0.00125697226804934
TF TF:M09636 Factor: MAZ; motif: GGGMGGGGSSGGGGGGGGGGGG 0.0276861836997534 16244 36 36 1 0.00221620290568825
TF TF:M11434 Factor: Elk-1; motif: NRSCGGAAGNN 0.0280103662983592 8219 14 12 0.857142857142857 0.00146003163401874
TF TF:M07250 Factor: E2F-1; motif: NNNSSCGCSAANN 0.0280103662983592 10703 36 29 0.805555555555556 0.00270952069513221
TF TF:M11448_1 Factor: Elf-1; motif: NANGCGGAAGTN; match class: 1 0.0280103662983592 2324 48 14 0.291666666666667 0.00602409638554217
TF TF:M11601 Factor: TCF-1; motif: ACATCGRGRCGCTGW 0.0282149088615274 14823 33 32 0.96969696969697 0.00215880725898941
TF TF:M04106_1 Factor: RUNX2; motif: NRACCGCAAACCGCAN; match class: 1 0.0283898233000089 8372 36 25 0.694444444444444 0.00298614429049212
TF TF:M10088 Factor: TBP; motif: MTATAAAARS 0.028547887972114 4934 5 5 1 0.00101337657073368
TF TF:M11396 Factor: Erg; motif: NACCGGAARTN 0.028547887972114 10765 54 41 0.759259259259259 0.00380863910822109
TF TF:M11491 Factor: LBP9; motif: ACYRGTTNNAACYRGT 0.0291286653481682 5146 74 32 0.432432432432432 0.00621842207539837
TF TF:M04064 Factor: Pax-5; motif: NGTCACGCWTSANTGMNY 0.030098041663444 10122 117 77 0.658119658119658 0.00760719225449516
TF TF:M11298 Factor: jdp2; motif: NRTGACGTCAYN 0.0302178287362699 1597 11 5 0.454545454545455 0.00313087038196619
TF TF:M09892 Factor: E2F-1; motif: NNNNGGCGGGAARN 0.0302178287362699 13528 36 33 0.916666666666667 0.00243938497930219
TF TF:M04617 Factor: LRF; motif: NGNAGNGGGTYN 0.0303265596065537 6164 30 18 0.6 0.00292018170019468
TF TF:M08220_1 Factor: Elk-1:HOXA3; motif: ACCGGWAATKRNNTNWCNNATTAN; match class: 1 0.0303389785884428 5350 19 12 0.631578947368421 0.00224299065420561
TF TF:M06948_1 Factor: Sp2; motif: TGGGCGCGCCCA; match class: 1 0.0303389785884428 6205 68 34 0.5 0.00547945205479452
TF TF:M12187 Factor: KLF17; motif: NMCCACNCWCCCNTN 0.0303389785884428 2886 7 5 0.714285714285714 0.00173250173250173
TF TF:M11061 Factor: HES-1; motif: GGCRCGTGNC 0.0303389785884428 6271 13 10 0.769230769230769 0.00159464200287036
TF TF:M00976 Factor: AhR,; motif: NRCGTGNGN 0.0306078990803754 4351 17 10 0.588235294117647 0.00229832222477591
TF TF:M07052 Factor: NRF-1; motif: GCGCMTGCGCN 0.0306078990803754 2130 31 10 0.32258064516129 0.00469483568075117
TF TF:M08207_1 Factor: E2F-3:TBR2; motif: ANGTGYKANGGCGCSTTNNCRNNT; match class: 1 0.0306078990803754 15466 38 37 0.973684210526316 0.00239234449760766
TF TF:M08878 Factor: EGR; motif: CGCCCCCGCNN 0.0306078990803754 7483 15 12 0.8 0.00160363490578645
TF TF:M10024_1 Factor: p63; motif: NRCAWGYCCAGRCWTGYNN; match class: 1 0.0307745272788396 326 13 3 0.230769230769231 0.00920245398773006
TF TF:M01241_1 Factor: BEN; motif: CWGCGAYA; match class: 1 0.0307745272788396 2097 17 7 0.411764705882353 0.0033381020505484
TF TF:M01118 Factor: WT1; motif: SMCNCCNSC 0.0316846500591165 6808 30 19 0.633333333333333 0.00279083431257344
TF TF:M03796_1 Factor: MafA; motif: GGTCAGCAGH; match class: 1 0.0316846500591165 681 24 5 0.208333333333333 0.00734214390602056
TF TF:M10632 Factor: Nkx2-8; motif: STCGTTGAN 0.0316846500591165 4871 57 25 0.43859649122807 0.00513241634161363
TF TF:M00017_1 Factor: ATF; motif: CNSTGACGTNNNYC; match class: 1 0.031969804004477 2222 111 24 0.216216216216216 0.0108010801080108
TF TF:M03874 Factor: Hoxa9; motif: ATYAATDACATC 0.0327288277350305 2481 32 11 0.34375 0.00443369609028618
TF TF:M11401_1 Factor: Fli-1; motif: NACCGGATATCCGGTN; match class: 1 0.0327524139760625 11801 13 13 1 0.0011016015591899
TF TF:M11530 Factor: E2F-2; motif: NWTTTGGCGCCAWWNN 0.0329207356455697 14593 120 103 0.858333333333333 0.00705817857877064
TF TF:M11018 Factor: IRX-1; motif: NACRYNNNNNNNNRYGNN 0.032978470666529 16955 44 44 1 0.00259510468888234
TF TF:M07297 Factor: MAZ; motif: CCCTCCCYCYN 0.032978470666529 2964 13 7 0.538461538461538 0.00236167341430499
TF TF:M11222 Factor: CREB1; motif: NRTGAYGTCAYN 0.0330884388137253 3688 11 7 0.636363636363636 0.00189804772234273
TF TF:M00179_1 Factor: ATF2; motif: VGTGACGTMACN; match class: 1 0.0331738410123743 1778 107 20 0.186915887850467 0.0112485939257593
TF TF:M07387 Factor: LRF; motif: NGKGGGTSNCN 0.0331738410123743 5232 5 5 1 0.00095565749235474
TF TF:M04694 Factor: NRF-1; motif: CNCTGCGCATGCGC 0.0336721626598363 1548 57 12 0.210526315789474 0.00775193798449612
TF TF:M00917 Factor: CREB; motif: CNNTGACGTMA 0.0344655450475472 5578 98 42 0.428571428571429 0.007529580494801
TF TF:M03990 Factor: GABPA; motif: ACCGGAAGTN 0.0347847147777406 5258 51 24 0.470588235294118 0.00456447318372005
TF TF:M11308_1 Factor: ATF-2; motif: NRTGAYGTMAYN; match class: 1 0.0352472921848793 1225 9 4 0.444444444444444 0.00326530612244898
TF TF:M10686 Factor: HOXB7; motif: GTCRTTAN 0.0352472921848793 3712 62 22 0.354838709677419 0.00592672413793103
TF TF:M03803_1 Factor: Sox-17; motif: TTGTYY; match class: 1 0.0352472921848793 9532 9 9 1 0.000944187998321444
TF TF:M03849_1 Factor: Sox-4; motif: AACAAA; match class: 1 0.0352472921848793 9090 50 34 0.68 0.00374037403740374
TF TF:M03976 Factor: ERG; motif: ACCGGAWATCCGGT 0.0352472921848793 12803 26 24 0.923076923076923 0.00187456064984769
TF TF:M09866 Factor: ATF-1; motif: NNRTGACGYMA 0.0352472921848793 3162 30 12 0.4 0.00379506641366224
TF TF:M03989 Factor: FLI1; motif: ACCGGAAATCCGGT 0.0354054474496152 10442 18 16 0.888888888888889 0.00153227351082168
TF TF:M11401 Factor: Fli-1; motif: NACCGGATATCCGGTN 0.0356467483597469 11952 13 13 1 0.00108768406961178
TF TF:M11291_1 Factor: ATF-3; motif: NRTGACGTCAYN; match class: 1 0.0359531895283863 4408 20 11 0.55 0.00249546279491833
TF TF:M08779 Factor: PXR; motif: AGTTCANNSAGTTC 0.0366498137171765 3913 6 5 0.833333333333333 0.00127779197546639
TF TF:M00185 Factor: NF-Y; motif: TRRCCAATSRN 0.0367675437926849 870 6 3 0.5 0.00344827586206897
TF TF:M10723 Factor: HOXD8; motif: RTCRTTAN 0.0373243515492555 4249 62 24 0.387096774193548 0.00564838785596611
TF TF:M10018 Factor: NRF-1; motif: CNSTGCGCATGCGCNNS 0.0373326428568886 1816 50 12 0.24 0.0066079295154185
TF TF:M00929 Factor: MyoD; motif: CNGNRNCAGGTGNNGNAN 0.0379965607202168 1488 4 3 0.75 0.00201612903225806
TF TF:M00025_1 Factor: Elk-1; motif: NNNNCCGGAARTNN; match class: 1 0.0384028654534086 4639 67 27 0.402985074626866 0.00582021987497305
TF TF:M00916 Factor: CREB; motif: NNTKACGTCANNNS 0.038629807793759 5889 32 18 0.5625 0.00305654610290372
TF TF:M10086 Factor: TAFII250; motif: RARRWGGCGGMGGNGR 0.0386427629890138 9262 12 11 0.916666666666667 0.00118764845605701
TF TF:M05432 Factor: ZSCAN18; motif: TRRCGRCGNMCC 0.0386427629890138 4117 13 8 0.615384615384615 0.00194316249696381
TF TF:M11492 Factor: LBP9; motif: ACYRGTNNNNACYRGT 0.0386936463413024 7582 97 52 0.536082474226804 0.00685834872065418
TF TF:M01118_1 Factor: WT1; motif: SMCNCCNSC; match class: 1 0.0386936463413024 2766 30 11 0.366666666666667 0.00397686189443239
TF TF:M11435_1 Factor: Elk-1; motif: NNCCGGAAGTN; match class: 1 0.0393114613908723 5745 53 26 0.490566037735849 0.00452567449956484
TF TF:M01820_1 Factor: CREM; motif: TGACGTCASYN; match class: 1 0.0404865117504883 1879 20 7 0.35 0.00372538584353379
TF TF:M00050 Factor: E2F; motif: TTTSGCGC 0.0407286367843038 7056 18 13 0.722222222222222 0.00184240362811791
TF TF:M07084 Factor: E2F-4; motif: NGGCGGGAARN 0.0410456010231272 10834 41 32 0.780487804878049 0.0029536643898837
TF TF:M11273 Factor: JunB; motif: GATGACGTCAYC 0.0412269188032844 9017 20 16 0.8 0.00177442608406344
TF TF:M02012 Factor: HIF-1alpha; motif: NCACGT 0.0412269188032844 6648 25 16 0.64 0.00240673886883273
TF TF:M00649 Factor: MAZ; motif: GGGGAGGG 0.0412269188032844 9327 18 15 0.833333333333333 0.00160823415889353
TF TF:M03977_1 Factor: ETS1; motif: ACCGGAARYN; match class: 1 0.0412269188032844 4677 67 27 0.402985074626866 0.00577293136626042
TF TF:M11400_1 Factor: Fli-1; motif: NACCGGAARTN; match class: 1 0.0412269188032844 4201 43 18 0.418604651162791 0.00428469412044751
TF TF:M02011 Factor: HES-1; motif: GSCACGMGMC 0.0412950352466723 4259 33 15 0.454545454545455 0.00352195351021367
TF TF:M10729 Factor: HOXC-8; motif: RTCRTTAN 0.0412950352466723 3956 56 21 0.375 0.00530839231547017
TF TF:M08487 Factor: GCMa:Erg; motif: ATGCGGGCGGAARKG 0.0414936837852897 13942 18 18 1 0.0012910629751829
TF TF:M02059 Factor: ELK-1; motif: ACCGGAAGTN 0.0414936837852897 9423 44 31 0.704545454545455 0.00328982277406346
TF TF:M11218 Factor: CREB1; motif: NRTGAYGCGTN 0.0414936837852897 8461 67 41 0.611940298507463 0.00484576291218532
TF TF:M11396_1 Factor: Erg; motif: NACCGGAARTN; match class: 1 0.0414936837852897 4963 43 20 0.465116279069767 0.00402982067298005
TF TF:M08457_1 Factor: ER71:SREBP-2; motif: NTSACGTGACGGAARY; match class: 1 0.041582750656958 5591 17 11 0.647058823529412 0.0019674476837775
TF TF:M00322 Factor: c-Myc:Max; motif: GCCAYGYGSN 0.042054189586852 7873 41 26 0.634146341463415 0.00330242601295567
TF TF:M04918 Factor: Egr-1; motif: ACCGCCC 0.0422903983760856 5608 17 11 0.647058823529412 0.00196148359486448
TF TF:M08905 Factor: TIEG1; motif: GGSGGKGNNN 0.0424297187738628 5153 39 19 0.487179487179487 0.00368717252086163
TF TF:M01770_1 Factor: XBP-1; motif: WNNGMCACGTC; match class: 1 0.0424297187738628 4554 120 42 0.35 0.00922266139657444
TF TF:M11081 Factor: SREBP-1; motif: RTCRCGTGAY 0.0424297187738628 11062 42 33 0.785714285714286 0.00298318568070873
TF TF:M11179_1 Factor: ASH-2; motif: ACACGACGCN; match class: 1 0.0429487511900512 165 107 5 0.0467289719626168 0.0303030303030303
TF TF:M11491_1 Factor: LBP9; motif: ACYRGTTNNAACYRGT; match class: 1 0.0430490966521999 4149 34 15 0.441176470588235 0.00361532899493854
TF TF:M11603 Factor: TCF-1; motif: ACATCGRGRCGCTGW 0.0431740121326633 16361 33 33 1 0.0020169916264287
TF TF:M02071_1 Factor: ETV7; motif: NCCGGAANNN; match class: 1 0.0432436634244812 4465 67 26 0.388059701492537 0.00582306830907055
TF TF:M10785 Factor: hoxa9; motif: RTCGTWANNN 0.0435695477062247 5632 99 42 0.424242424242424 0.00745738636363636
TF TF:M08205 Factor: E2F-1:Elk-1; motif: SGCGCSNNAMCGGAAGT 0.0435695477062247 14429 68 60 0.882352941176471 0.00415829232795065
TF TF:M00981_1 Factor: CREB,; motif: NTGACGTNA; match class: 1 0.0435695477062247 2904 115 29 0.252173913043478 0.0099862258953168
TF TF:M03896 Factor: EGR1; motif: NACGCCCACGCANW 0.0436980206454109 6129 16 11 0.6875 0.00179474628813836
TF TF:M08583 Factor: GCMa:Max; motif: ATGCGGGTNNNNNNCACGTGN 0.0441758457399314 206 25 3 0.12 0.0145631067961165
TF TF:M00232 Factor: MEF-2A; motif: NNNNNWKCTAWAAATAGMNNNN 0.0453166201249942 1421 49 10 0.204081632653061 0.00703729767769177
TF TF:M00072_1 Factor: CP2; motif: GCHCDAMCCAG; match class: 1 0.0466012041351887 2750 15 7 0.466666666666667 0.00254545454545455
TF TF:M08759 Factor: c-Ets-2; motif: NCCGGAAGTG 0.0466012041351887 8319 18 14 0.777777777777778 0.00168289457867532
TF TF:M05327 Factor: WT1; motif: NGCGGGGGGGTSMMCYN 0.0466012041351887 5509 13 9 0.692307692307692 0.00163369032492285
TF TF:M00956 Factor: AR; motif: NNNNNNRGNACRNNGTGTTCTNNNNNN 0.0466012041351887 2717 19 8 0.421052631578947 0.00294442399705558
TF TF:M06621 Factor: ZNF479; motif: NSKACAAAMAGC 0.0467452057720918 182 29 3 0.103448275862069 0.0164835164835165
TF TF:M07460 Factor: KLF3; motif: CCMCRCCCNG 0.0474257564795891 1437 57 11 0.192982456140351 0.00765483646485734
TF TF:M05775 Factor: ZXDL; motif: NGGGGWS 0.0474257564795891 6964 87 44 0.505747126436782 0.00631820792647904
TF TF:M11078 Factor: TCFL5; motif: KCACGCGCNC 0.0474257564795891 1471 33 8 0.242424242424242 0.00543847722637661
TF TF:M03977 Factor: ETS1; motif: ACCGGAARYN 0.0477049060479668 10512 94 64 0.680851063829787 0.0060882800608828
TF TF:M11392_1 Factor: Erg; motif: NACCGGAARYN; match class: 1 0.0477049060479668 3233 43 15 0.348837209302326 0.00463965357253325
TF TF:M09895 Factor: E2F-6; motif: NGGGCGGGARRNN 0.0477049060479668 7765 36 23 0.638888888888889 0.00296200901481004
TF TF:M08891_1 Factor: NFKAPPAB; motif: NNGGGANTTCCCN; match class: 1 0.0477049060479668 181 102 5 0.0490196078431373 0.0276243093922652
TF TF:M01242 Factor: MTF-1; motif: GTGTGCANMACTTTGCGCAC 0.0477049060479668 3931 17 9 0.529411764705882 0.00228949376748919
TF TF:M04710 Factor: CHD2; motif: TCTCGCGAG 0.0477049060479668 14109 37 34 0.918918918918919 0.00240980934155504
TF TF:M01862 Factor: ATF-2; motif: NNNTGACGTNAN 0.0477049060479668 3230 20 9 0.45 0.00278637770897833
TF TF:M00807 Factor: Egr; motif: GTGGGSGCRRS 0.0481986009583121 4343 87 31 0.35632183908046 0.00713792309463504
WP WP:WP2359 Parkin-Ubiquitin Proteasomal System pathway 0.000434058536865669 70 14 4 0.285714285714286 0.0571428571428571
WP WP:WP2880 Glucocorticoid Receptor Pathway 0.000434058536865669 71 29 5 0.172413793103448 0.0704225352112676
WP WP:WP382 MAPK Signaling Pathway 0.000434058536865669 249 14 6 0.428571428571429 0.0240963855421687
WP WP:WP2884 NRF2 pathway 0.00141272753007033 145 4 3 0.75 0.0206896551724138
WP WP:WP2882 Nuclear Receptors Meta-Pathway 0.00206406415443876 321 11 5 0.454545454545455 0.0155763239875389
WP WP:WP3888 VEGFA-VEGFR2 Signaling Pathway 0.0122377140983209 437 12 5 0.416666666666667 0.011441647597254
WP WP:WP3863 T-Cell antigen Receptor (TCR) pathway during Staphylococcus aureus infection 0.0346913270745867 62 61 4 0.0655737704918033 0.0645161290322581
WP WP:WP4216 Chromosomal and microsatellite instability in colorectal cancer 0.0485375038881066 74 33 3 0.0909090909090909 0.0405405405405405

pTNI15 transcription factor target enrichment of top program genes

TF enrichment of pTNI15
TFs corrosponding to activation of pTNI15. (Left) pearson correlation of TF expression and gene expression program activatity in T/NK/ILC cells, (right) negative log p-value for enrichment of TF binding sites among top uniqueness weighted genes for the gene program. Blue bars indicate significant TFs meeting the following criteria: FDR<0.1, overlap > 2, Corr. R > 0, permutation based p-value < 0.05.